{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T10:15:44Z","timestamp":1752228944139},"publisher-location":"Totowa, NJ","reference-count":15,"publisher":"Humana Press","isbn-type":[{"type":"print","value":"9781607617556"},{"type":"electronic","value":"9781607617563"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010]]},"DOI":"10.1007\/978-1-60761-756-3_14","type":"book-chapter","created":{"date-parts":[[2010,8,10]],"date-time":"2010-08-10T20:53:15Z","timestamp":1281473595000},"page":"215-229","source":"Crossref","is-referenced-by-count":11,"title":["Transcription Factor Sequestration by Polyglutamine Proteins"],"prefix":"10.1007","author":[{"given":"Tomoyuki","family":"Yamanaka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuyuki","family":"Nukina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2010,7,7]]},"reference":[{"key":"14_CR1_14","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1016\/0092-8674(93)90585-E","volume":"72","author":"The Huntington\u2019s Disease Collaborative Research and Group","year":"1993","unstructured":"The Huntington\u2019s Disease Collaborative Research and Group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington\u2019s disease chromosomes. Cell 72:971\u2013983","journal-title":"Cell"},{"key":"14_CR2_14","doi-asserted-by":"publisher","first-page":"958","DOI":"10.1038\/sj.embor.7400250","volume":"5","author":"C Landles","year":"2004","unstructured":"Landles C, Bates GP (2004) Huntingtin and the molecular pathogenesis of Huntington\u2019s disease. Fourth in molecular medicine review series. EMBO Rep 5:958\u2013963","journal-title":"EMBO Rep"},{"key":"14_CR3_14","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.tig.2004.01.008","volume":"20","author":"SH Li","year":"2004","unstructured":"Li SH, Li XJ (2004) Huntingtin-protein interactions and the pathogenesis of Huntington\u2019s disease. Trends Genet 20:146\u2013154","journal-title":"Trends Genet"},{"key":"14_CR4_14","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1016\/S0968-0004(03)00168-3","volume":"28","author":"P Harjes","year":"2003","unstructured":"Harjes P, Wanker EE (2003) The hunt for huntingtin function: interaction partners tell many different stories. Trends Biochem Sci 28:425\u2013433","journal-title":"Trends Biochem Sci"},{"key":"14_CR5_14","doi-asserted-by":"publisher","first-page":"1911","DOI":"10.1093\/hmg\/11.17.1911","volume":"11","author":"R Luthi-Carter","year":"2002","unstructured":"Luthi-Carter R, Hanson SA, Strand AD, Bergstrom DA, Chun W, Peters NL, Woods AM, Chan EY, Kooperberg C, Krainc D, Young AB, Tapscott SJ, Olson JM (2002) Dysregulation of gene expression in the R6\/2 model of polyglutamine disease: parallel changes in muscle and brain. Hum Mol Genet 11:1911\u20131926","journal-title":"Hum Mol Genet"},{"key":"14_CR6_14","doi-asserted-by":"publisher","first-page":"1939","DOI":"10.1093\/hmg\/11.17.1939","volume":"11","author":"EY Chan","year":"2002","unstructured":"Chan EY, Luthi-Carter R, Strand A, Solano SM, Hanson SA, DeJohn MM, Kooperberg C, Chase KO, DiFiglia M, Young AB, Leavitt BR, Cha JH, Aronin N, Hayden MR, Olson JM (2002) Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington\u2019s disease. Hum Mol Genet 11:1939\u20131951","journal-title":"Hum Mol Genet"},{"key":"14_CR7_14","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1111\/j.1471-4159.2005.03035.x","volume":"93","author":"S Kotliarova","year":"2005","unstructured":"Kotliarova S, Jana NR, Sakamoto N, Kurosawa M, Miyazaki H, Nekooki M, Doi H, Machida Y, Wong HK, Suzuki T, Uchikawa C, Kotliarov Y, Uchida K, Nagao Y, Nagaoka U, Tamaoka A, Oyanagi K, Oyama F, Nukina N (2005) Decreased expression of hypotha-lamic neuropeptides in Huntington disease transgenic mice with expanded polyglutamine-EGFP fluorescent aggregates. J Neurochem 93:641\u2013653","journal-title":"J Neurochem"},{"key":"14_CR8_14","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/S0168-9525(03)00074-X","volume":"19","author":"KL Sugars","year":"2003","unstructured":"Sugars KL, Rubinsztein DC (2003) Transcriptional abnormalities in Huntington disease. Trends Genet 19:233\u2013238","journal-title":"Trends Genet"},{"key":"14_CR9_14","doi-asserted-by":"publisher","first-page":"2183","DOI":"10.1101\/gad.1436506","volume":"20","author":"BE Riley","year":"2006","unstructured":"Riley BE, Orr HT (2006) Polyglutamine neurodegenerative diseases and regulation of transcription: assembling the puzzle. Genes Dev 20:2183\u20132192","journal-title":"Genes Dev"},{"key":"14_CR10_14","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/S0166-2236(00)01609-X","volume":"23","author":"JH Cha","year":"2000","unstructured":"Cha JH (2000) Transcriptional dysregulation in Huntington\u2019s disease. Trends Neurosci 23:387\u2013392","journal-title":"Trends Neurosci"},{"key":"14_CR11_14","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1038\/emboj.2008.23","volume":"27","author":"T Yamanaka","year":"2008","unstructured":"Yamanaka T, Miyazaki H, Oyama F, Kurosawa M, Washizu C, Doi H, Nukina N (2008) Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor. EMBO J 27:827\u2013839","journal-title":"EMBO J"},{"key":"14_CR12_14","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.febslet.2004.06.077","volume":"571","author":"H Doi","year":"2004","unstructured":"Doi H, Mitsui K, Kurosawa M, Machida Y, Kuroiwa Y, Nukina N (2004) Identification of ubiquitin-interacting proteins in purified polyglutamine aggregates. FEBS Lett 571:171\u2013176","journal-title":"FEBS Lett"},{"key":"14_CR13_14","doi-asserted-by":"publisher","first-page":"41452","DOI":"10.1074\/jbc.M303354200","volume":"278","author":"A Busch","year":"2003","unstructured":"Busch A, Engemann S, Lurz R, Okazawa H, Lehrach H, Wanker EE (2003) Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington\u2019s disease. J Biol Chem 278:41452\u201341461","journal-title":"J Biol Chem"},{"key":"14_CR14_14","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1016\/S0092-8674(00)80514-0","volume":"90","author":"E Scherzinger","year":"1997","unstructured":"Scherzinger E, Lurz R, Turmaine M, Mangiarini L, Hollenbach B, Hasenbank R, Bates GP, Davies SW, Lehrach H, Wanker EE (1997) Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo. Cell 90:549\u2013558","journal-title":"Cell"},{"key":"14_CR15_14","doi-asserted-by":"crossref","first-page":"4736","DOI":"10.1128\/MCB.8.11.4736","volume":"8","author":"DD Mosser","year":"1988","unstructured":"Mosser DD, Theodorakis NG, Morimoto RI (1988) Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells. Mol Cell Biol 8:4736\u20134744","journal-title":"Mol Cell Biol"}],"container-title":["Methods in Molecular Biology","Protein Misfolding and Cellular Stress in Disease and Aging"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-60761-756-3_14","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,18]],"date-time":"2019-03-18T01:48:39Z","timestamp":1552873719000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-60761-756-3_14"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"ISBN":["9781607617556","9781607617563"],"references-count":15,"URL":"https:\/\/doi.org\/10.1007\/978-1-60761-756-3_14","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"type":"print","value":"1064-3745"},{"type":"electronic","value":"1940-6029"}],"subject":[],"published":{"date-parts":[[2010]]}}}