{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T07:13:12Z","timestamp":1794381192465,"version":"4.9.0"},"publisher-location":"Totowa, NJ","reference-count":34,"publisher":"Humana Press","isbn-type":[{"value":"9781607618447","type":"print"},{"value":"9781607618454","type":"electronic"}],"license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010]]},"DOI":"10.1007\/978-1-60761-845-4_17","type":"book-chapter","created":{"date-parts":[[2010,9,20]],"date-time":"2010-09-20T18:17:36Z","timestamp":1285006656000},"page":"209-224","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["A Microarray-Based Method to Perform Nucleic Acid Selections"],"prefix":"10.1007","author":[{"given":"Olga","family":"Aminova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew D.","family":"Disney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,8,19]]},"reference":[{"key":"17_CR1_17","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1038\/346818a0","volume":"346","author":"AD Ellington","year":"1990","unstructured":"Ellington, A. D., and Szostak, J. W. (1990) In vitro selection of RNA molecules that bind specific ligands, Nature\n                        346, 818\u2013822.","journal-title":"Nature"},{"key":"17_CR2_17","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1038\/355850a0","volume":"355","author":"AD Ellington","year":"1992","unstructured":"Ellington, A. D., and Szostak, J. W. (1992) Selection in vitro of single-stranded DNA molecules that fold into specific ligand-binding structures, Nature\n                        355, 850\u2013852.","journal-title":"Nature"},{"key":"17_CR3_17","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1021\/cr960009c","volume":"97","author":"SE Osborne","year":"1997","unstructured":"Osborne, S. E., and Ellington, A. D. (1997) Nucleic acid selection and the challenge of combinatorial chemistry, Chem. Rev.\n                        97, 349\u2013370.","journal-title":"Chem. Rev."},{"key":"17_CR4_17","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1126\/science.2200121","volume":"249","author":"C Tuerk","year":"1990","unstructured":"Tuerk, C., and Gold, L. (1990) Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase, Science\n                        249, 505\u2013510.","journal-title":"Science"},{"key":"17_CR5_17","doi-asserted-by":"publisher","first-page":"2525","DOI":"10.1016\/S0968-0896(01)00028-1","volume":"9","author":"JC Cox","year":"2001","unstructured":"Cox, J. C., and Ellington, A. D. (2001) Automated selection of anti-protein aptamers, Bioorg. Med. Chem.\n                        9, 2525\u20132531.","journal-title":"Bioorg. Med. Chem."},{"key":"17_CR6_17","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/0378-1119(93)90246-Y","volume":"137","author":"L Giver","year":"1993","unstructured":"Giver, L., Bartel, D. P., Zapp, M. L., Green, M. R., and Ellington, A. D. (1993) Selection and design of high-affinity RNA ligands for HIV-1 REV, Gene\n                        137, 19\u201324.","journal-title":"Gene"},{"key":"17_CR7_17","doi-asserted-by":"publisher","first-page":"4937","DOI":"10.1074\/jbc.275.7.4937","volume":"275","author":"JR Hesselberth","year":"2000","unstructured":"Hesselberth, J. R., Miller, D., Robertus, J., and Ellington, A. D. (2000) In vitro selection of RNA molecules that inhibit the activity of ricin A-chain, J. Biol. Chem.\n                        275, 4937\u20134942.","journal-title":"J. Biol. Chem."},{"key":"17_CR8_17","doi-asserted-by":"publisher","first-page":"15416","DOI":"10.1073\/pnas.2136683100","volume":"100","author":"DA Daniels","year":"2003","unstructured":"Daniels, D. A., Chen, H., Hicke, B. J., Swiderek, K. M., and Gold, L. (2003) A tenascin-C aptamer identified by tumor cell SELEX: Systematic evolution of ligands by exponential enrichment, Proc. Natl. Acad. Sci. U.S.A.\n                        100, 15416\u201315421.","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"17_CR9_17","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1016\/j.tibtech.2008.02.005","volume":"26","author":"M Minunni","year":"2008","unstructured":"Minunni, M., Scarano, S., and Mascini, M. (2008) Affinity-based biosensors as promising tools for gene doping detection, Trends Biotechnol.\n                        26, 236\u2013243.","journal-title":"Trends Biotechnol."},{"key":"17_CR10_17","doi-asserted-by":"publisher","first-page":"3715","DOI":"10.1021\/cr0306743","volume":"107","author":"M Famulok","year":"2007","unstructured":"Famulok, M., Hartig, J. S., and Mayer, G. (2007) Functional aptamers and aptazymes in biotechnology, diagnostics, and therapy, Chem. Rev.\n                        107, 3715\u20133743.","journal-title":"Chem. Rev."},{"key":"17_CR11_17","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.cellimm.2008.04.001","volume":"251","author":"CC Wu","year":"2008","unstructured":"Wu, C. C., Sabet, M., Hayashi, T., Tawatao, R., Fierer, J., Carson, D. A., Guiney, D. G., and Corr, M. (2008) In vivo efficacy of a phosphodiester TLR-9 aptamer and its beneficial effect in a pulmonary anthrax infection model, Cell Immunol.\n                        251, 78\u201385.","journal-title":"Cell Immunol."},{"key":"17_CR12_17","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.coph.2007.12.005","volume":"8","author":"AD Keefe","year":"2008","unstructured":"Keefe, A. D., and Schaub, R. G. (2008) Aptamers as candidate therapeutics for cardiovascular indications, Curr. Opin. Pharmacol.\n                        8, 147\u2013152.","journal-title":"Curr. Opin. Pharmacol."},{"key":"17_CR13_17","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1038\/371031a0","volume":"371","author":"JR Lorsch","year":"1994","unstructured":"Lorsch, J. R., and Szostak, J. W. (1994) In vitro evolution of new ribozymes with polynucleotide kinase activity, Nature\n                        371, 31\u201336.","journal-title":"Nature"},{"key":"17_CR14_17","doi-asserted-by":"publisher","first-page":"1411","DOI":"10.1126\/science.7690155","volume":"261","author":"DP Bartel","year":"1993","unstructured":"Bartel, D. P., and Szostak, J. W. (1993) Isolation of new ribozymes from a large pool of random sequences [see comment], Science\n                        261, 1411\u20131418.","journal-title":"Science"},{"key":"17_CR15_17","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1021\/ja037832s","volume":"126","author":"SD Mendonsa","year":"2004","unstructured":"Mendonsa, S. D., and Bowser, M. T. (2004) In vitro evolution of functional DNA using capillary electrophoresis, J. Am. Chem. Soc.\n                        126, 20\u201321.","journal-title":"J. Am. Chem. Soc."},{"key":"17_CR16_17","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/BF00996358","volume":"20","author":"SJ Klug","year":"1994","unstructured":"Klug, S. J., and Famulok, M. (1994) All you wanted to know about SELEX, Mol. Biol. Rep.\n                        20, 97\u2013107.","journal-title":"Mol. Biol. Rep."},{"key":"17_CR17_17","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1126\/science.270.5235.467","volume":"270","author":"M Schena","year":"1995","unstructured":"Schena, M., Shalon, D., Davis, R. W., and Brown, P. O. (1995) Quantitative monitoring of gene expression patterns with a complementary DNA microarray, Science\n                        270, 467\u2013470.","journal-title":"Science"},{"key":"17_CR18_17","doi-asserted-by":"crossref","first-page":"1760","DOI":"10.1126\/science.289.5485.1760","volume":"289","author":"G MacBeath","year":"2000","unstructured":"MacBeath, G., and Schreiber, S. L. (2000) Printing proteins as microarrays for high-throughput function determination, Science\n                        289, 1760\u20131763.","journal-title":"Science"},{"key":"17_CR19_17","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1016\/S1074-5521(02)00124-2","volume":"9","author":"BT Houseman","year":"2002","unstructured":"Houseman, B. T., and Mrksich, M. (2002) Carbohydrate arrays for the evaluation of protein binding and enzymatic modification, Chem. Biol.\n                        9, 400\u2013401.","journal-title":"Chem. Biol."},{"key":"17_CR20_17","doi-asserted-by":"publisher","first-page":"1882","DOI":"10.1002\/cbic.200600260","volume":"7","author":"OJ Barrett","year":"2006","unstructured":"Barrett, O. J., Childs, J. L., and Disney, M. D. (2006) Chemical microarrays to identify ligands that bind pathogenic cells, Chembiochem\n                        7, 1882\u20131885.","journal-title":"Chembiochem"},{"key":"17_CR21_17","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1002\/anie.200353236","volume":"43","author":"MD Disney","year":"2004","unstructured":"Disney, M. D., Magnet, S., Blanchard, J. S., and Seeberger, P. H. (2004) Aminoglycoside microarrays to study antibiotic resistance, Angew. Chem. Int. Ed.\n                        43, 1591\u20131594.","journal-title":"Angew. Chem. Int. Ed."},{"key":"17_CR22_17","doi-asserted-by":"publisher","first-page":"2344","DOI":"10.1038\/nprot.2006.282","volume":"1","author":"JE Bradner","year":"2006","unstructured":"Bradner, J. E., McPherson, O. M., and Koehler, A. N. (2006) A method for the covalent capture and screening of diverse small molecules in a microarray format, Nat. Prot.\n                        1, 2344\u20132352.","journal-title":"Nat. Prot."},{"key":"17_CR23_17","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.cbpa.2006.11.031","volume":"11","author":"JL Duffner","year":"2007","unstructured":"Duffner, J. L., Clemons, P. A., and Koehler, A. N. (2007) A pipeline for ligand discovery using small-molecule microarrays, Curr. Opin. Chem. Biol.\n                        11, 74\u201382.","journal-title":"Curr. Opin. Chem. Biol."},{"key":"17_CR24_17","doi-asserted-by":"publisher","first-page":"7967","DOI":"10.1021\/ja991083q","volume":"121","author":"G MacBeath","year":"1999","unstructured":"MacBeath, G., Koehler, A. N., and Schreiber, S. L. (1999) Printing small molecules as microarrays and detecting protein-ligand interactions en masse, J. Am. Chem. Soc.\n                        121, 7967\u20137968.","journal-title":"J. Am. Chem. Soc."},{"key":"17_CR25_17","doi-asserted-by":"publisher","first-page":"E66","DOI":"10.1093\/nar\/28.12.e66","volume":"28","author":"V Afanassiev","year":"2000","unstructured":"Afanassiev, V., Hannemann, V., and Wolfl, S. (2000) Preparation of DNA and protein micro arrays on glass slides coated with an agarose film, Nucleic Acids Res.\n                        28, E66.","journal-title":"Nucleic Acids Res."},{"key":"17_CR26_17","doi-asserted-by":"crossref","first-page":"286","DOI":"10.2144\/04372MT02","volume":"37","author":"M Dufva","year":"2004","unstructured":"Dufva, M., Petronis, S., Jensen, L. B., Krag, C., and Christensen, C. B. (2004) Characterization of an inexpensive, nontoxic, and highly sensitive microarray substrate. Biotechniques\n                        37, 286\u2013292, 294, 296.","journal-title":"Biotechniques"},{"key":"17_CR27_17","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1021\/cb700174r","volume":"2","author":"JL Childs-Disney","year":"2007","unstructured":"Childs-Disney, J. L., Wu, M., Pushechnikov, A., Aminova, O., and Disney, M. D. (2007) A small molecule microarray platform to select RNA internal loop-ligand interactions, ACS Chem. Biol.\n                        2, 745\u2013754.","journal-title":"ACS Chem. Biol."},{"key":"17_CR28_17","doi-asserted-by":"publisher","first-page":"11185","DOI":"10.1021\/ja803234t","volume":"130","author":"MD Disney","year":"2008","unstructured":"Disney, M. D., Labuda, L. P., Paul, D. J., Poplawski, S. G., Pushechnikov, A., Tran, T., Velagapudi, S. P., Wu, M., and Childs-Disney, J. L. (2008) Two-dimensional combinatorial screening identifies specific aminoglycoside-RNA internal loop partners, J. Am. Chem. Soc.\n                        130, 11185\u201311194.","journal-title":"J. Am. Chem. Soc."},{"key":"17_CR29_17","doi-asserted-by":"publisher","first-page":"2853","DOI":"10.1021\/ol0493094","volume":"6","author":"TR Chan","year":"2004","unstructured":"Chan, T. R., Hilgraf, R., Sharpless, B., and Fokin, V. V. (2004) Polytriazoles as copper(I)-stabilizing ligand in catalysis, Org. Lett.\n                        6, 2853\u20132855.","journal-title":"Org. Lett."},{"key":"17_CR30_17","doi-asserted-by":"publisher","first-page":"2004","DOI":"10.1002\/1521-3773(20010601)40:11<2004::AID-ANIE2004>3.0.CO;2-5","volume":"40","author":"HC Kolb","year":"2001","unstructured":"Kolb, H. C., Finn, M. G., and Sharpless, K. B. (2001) Click chemistry: diverse chemical function from a few good reactions, Angew. Chem. Int. Ed.\n                        40, 2004\u20132021.","journal-title":"Angew. Chem. Int. Ed."},{"key":"17_CR31_17","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/0076-6879(89)80091-6","volume":"180","author":"JF Milligan","year":"1989","unstructured":"Milligan, J. F., and Uhlenbeck, O. C. (1989) Synthesis of small RNAs using T7 RNA polymerase, Methods Enzymol.\n                        180, 51\u201362.","journal-title":"Methods Enzymol."},{"key":"17_CR32_17","unstructured":"Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning, Vol. 1, Cold Spring Harbor, NY."},{"key":"17_CR33_17","doi-asserted-by":"publisher","first-page":"3468","DOI":"10.1021\/bi9825091","volume":"38","author":"N Peyret","year":"1999","unstructured":"Peyret, N., Seneviratne, P. A., Allawi, H. T., and SantaLucia Jr, J. (1999) Nearest-neighbor thermodynamics and NMR of DNA sequences with internal A-A, C-C, G-G, and T-T mismatches, Biochemistry\n                        38, 3468\u20133477.","journal-title":"Biochemistry"},{"key":"17_CR34_17","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.1073\/pnas.95.4.1460","volume":"95","author":"J SantaLucia Jr","year":"1998","unstructured":"SantaLucia Jr, J. (1998) A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics, Proc. Natl. Acad. Sci. U.S.A.\n                        95, 1460\u20131465.","journal-title":"Proc. Natl. Acad. Sci. U.S.A."}],"container-title":["Methods in Molecular Biology","Small Molecule Microarrays"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-60761-845-4_17","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T21:16:16Z","timestamp":1676668576000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-60761-845-4_17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010]]},"ISBN":["9781607618447","9781607618454"],"references-count":34,"URL":"https:\/\/doi.org\/10.1007\/978-1-60761-845-4_17","relation":{"is-part-of":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1007\/978-1-60761-845-4","asserted-by":"object"}]},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010]]},"assertion":[{"value":"19 August 2010","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}