{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T08:24:01Z","timestamp":1794385441550,"version":"4.9.0"},"publisher-location":"Totowa, NJ","reference-count":32,"publisher":"Humana Press","isbn-type":[{"value":"9781617790119","type":"print"},{"value":"9781617790126","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011]]},"DOI":"10.1007\/978-1-61779-012-6_15","type":"book-chapter","created":{"date-parts":[[2011,2,11]],"date-time":"2011-02-11T18:15:45Z","timestamp":1297448145000},"page":"245-265","source":"Crossref","is-referenced-by-count":5,"title":["Evaluation of Antibacterial Activity of Proteins and Peptides Using a Specific Animal Model for Wound Healing"],"prefix":"10.1007","author":[{"given":"Ramar Perumal","family":"Samy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maung Maung","family":"Thwin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent T. K.","family":"Chow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ho","family":"Bow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ponnampalam","family":"Gopalakrishnakone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,1,14]]},"reference":[{"key":"15_CR1_15","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1126\/science.276.5309.75","volume":"276","author":"P Martin","year":"1997","unstructured":"Martin, P. (1997) Wound healing-aiming for perfect skin regeneration. Science 276: 75\u201381.","journal-title":"Science"},{"key":"15_CR2_15","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1007\/978-3-7643-7650-5_5","volume-title":"Progress in Inflammation Research- Angiogenesis in Inflammation: Mechanisms and Clinical Correlates","author":"P Auguste","year":"2008","unstructured":"Auguste, P., Vincent, F., Gabbiani, G., Desmouli\u00e8re, A. (2008) The fibroblast and myofibroblast in inflammatory angiogenesis. In: Seed MP and Walsh DA (eds) Progress in Inflammation Research- Angiogenesis in Inflammation: Mechanisms and Clinical Correlates, Birkh\u00e4user Basel, Springer pp 59\u201382."},{"key":"15_CR3_15","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1016\/j.tcb.2005.09.002","volume":"15","author":"P Martin","year":"2005","unstructured":"Martin, P., Leibovich, S. J. (2005) Inflammatory cells during wound repair: the good, the bad and the ugly. Trends Cell Biol. 15: 599\u2013607.","journal-title":"Trends Cell Biol."},{"key":"15_CR4_15","doi-asserted-by":"crossref","first-page":"7556","DOI":"10.4049\/jimmunol.166.12.7556","volume":"166","author":"R Abe","year":"2001","unstructured":"Abe, R., Donnelly, S. C., Peng, T., Bucala, R., Metz, C. N. (2001) Peripheral blood fibrocytes: differentiation pathway and migration to wound sites. J Immunol. 166: 7556\u20137562.","journal-title":"J Immunol."},{"key":"15_CR5_15","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1016\/j.biocel.2003.10.005","volume":"36","author":"TE Quan","year":"2004","unstructured":"Quan, T. E., Cowper, S., Wu, S. P., Bockenstedt, L. K., Bucala, R. (2004) Circulating fibrocytes: collagen-secreting cells of the peripheral blood. Int J Biochem Cell Biol. 36: 598\u2013606.","journal-title":"Int J Biochem Cell Biol."},{"key":"15_CR6_15","doi-asserted-by":"publisher","first-page":"S114","DOI":"10.1086\/320184","volume":"(Suppl 2) 32","author":"DJ Diekema","year":"2001","unstructured":"Diekema, D. J., Pfaller, M. A., Schmitz, F. J., Smayevsky, J., Bell, J., Jones, R. N., Beach, M. (2001) Survey of infections due to Staphylococcus species: frequency of occurrence and antimicrobial susceptibility of isolates collected in the United States, Canada, Latin America, Europe, and the Western Pacific region for the SENTRY Antimicrobial Surveillance Program, 1997-1999. Clin Infect Dis. 32: S114\u2013S132.","journal-title":"Clin Infect Dis."},{"key":"15_CR7_15","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1002\/path.1898","volume":"208","author":"H Komatsuzawa","year":"2006","unstructured":"Komatsuzawa, H., Ouhara, K., Yamada, S., Fujiwara, T., Sayama, K., Koji Hashimoto, K., Motoyuki Sugai, M. (2006) Innate defences against methicillin-resistant Staphylococcus aureus (MRSA) infection. J Pathol. 208: 249\u2013260.","journal-title":"J Pathol."},{"key":"15_CR8_15","first-page":"67","volume-title":"Fifty years of antimicrobials: past perspectives and future trends","author":"H Z\u00e4hner","year":"1995","unstructured":"Z\u00e4hner, H., Fiedler. H. P. (1995) The need for new antibiotics: possible ways forward. In: Hunter P. A., Darby G. K., Russell N. J. (eds.) Fifty years of antimicrobials: past perspectives and future trends. Cambridge University Press, Cambridge, England, pp 67\u201385."},{"key":"15_CR9_15","doi-asserted-by":"publisher","first-page":"1414","DOI":"10.1086\/317489","volume":"31","author":"RA Bonomo","year":"2000","unstructured":"Bonomo, R. A. (2000) Multiple antibiotic-resistant bacteria in long-term-care facilities: an emerging problem in the practice of infectious diseases. Clin Infect Dis. 31: 1414\u20131422.","journal-title":"Clin Infect Dis."},{"key":"15_CR10_15","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1067\/mic.2000.106904","volume":"28","author":"AH Wong","year":"2000","unstructured":"Wong, A. H., Wenzel, R. P., Edmond. M. B. (2000) Epidemiology of bacteriuria caused by vancomycin-resistant enterococci-a retrospective study. Am J Infect Control. 28: 277\u2013281.","journal-title":"Am J Infect Control"},{"key":"15_CR11_15","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/S0924-8579(01)00378-8","volume":"18","author":"JD Williams","year":"2001","unstructured":"Williams, J. D. (2001) Antibiotic resistance in hospital pathogens-acquisition or spread?. Int J Antimicrob Agents. 18: 295\u2013298.","journal-title":"Int. J Antimicrob Agents"},{"key":"15_CR12_15","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1002\/1097-0282(2000)55:1<31::AID-BIP40>3.0.CO;2-9","volume":"55","author":"R Gennaro","year":"2000","unstructured":"Gennaro, R., Zanetti, M. (2000) Structural features and biological activities of the cathelicidin-derived antimicrobial peptides. Biopolymers. 55: 31\u201349.","journal-title":"Biopolymers"},{"key":"15_CR13_15","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1189\/jlb.0403147","volume":"75","author":"M Zanetti","year":"2004","unstructured":"Zanetti M. (2004) Cathelicidins, multifunctional peptides of the innate immunity. J Leukoc Biol. 75: 39\u201348.","journal-title":"J Leukoc Biol."},{"key":"15_CR14_15","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1046\/j.1432-1327.1998.2530452.x","volume":"253","author":"L Paramo","year":"1998","unstructured":"Paramo, L., Lomonte, B., Pizarro-Cerda, J., Bengoechea, J. A., Gorvel, J. P., Moreno, E. (1998) Bactericidal activity of Lys49 and Asp49 myotoxic phospholipases A2 from Bothrops asper snake venom: synthetic Lys49 myotoxin II-(115\u2013129)- peptide identifies its bactericidal region. Eur J Biochem. 253: 452\u2013461.","journal-title":"Eur J Biochem."},{"key":"15_CR15_15","doi-asserted-by":"publisher","first-page":"885","DOI":"10.1016\/j.toxicon.2003.11.008","volume":"42","author":"B Lomonte","year":"2003","unstructured":"Lomonte, B., Angulo, Y., Calderon, L. (2003) An overview of Lysine-49 phospholipase A2 myotoxins from crotalid snake venoms and their structural determinants of myotoxic action. Toxicon. 42: 885\u2013901.","journal-title":"Toxicon"},{"key":"15_CR16_15","doi-asserted-by":"crossref","first-page":"29867","DOI":"10.1016\/S0021-9258(18)43961-0","volume":"269","author":"B Lomonte","year":"1994","unstructured":"Lomonte, B., Moreno, E., Tarkowski, A., Hanson, L. A., Maccarana, M. (1994) Neutralizing interaction between heparins and myotoxin II, a Lys-49 phospholipase A2 from Bothrops asper snake venom. J Biol Chem. 269: 29867\u201329873.","journal-title":"J Biol Chem."},{"key":"15_CR17_15","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1007\/978-1-60761-594-1_19","volume":"618","author":"L Zhang","year":"2010","unstructured":"Zhang, L., Falla, T.J. (2010) Potential therapeutic application of host defense peptides. Methods Mol Biol. 618: 303\u2013327.","journal-title":"Methods Mol Biol."},{"key":"15_CR18_15","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1038\/227680a0","volume":"227","author":"UK Laemmli","year":"1970","unstructured":"Laemmli, U.K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage. Nature 227: 680\u2013685.","journal-title":"Nature"},{"key":"15_CR19_15","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Ann Biochem. 72: 248\u2013254.","journal-title":"Ann Biochem."},{"key":"15_CR20_15","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/S0065-2911(08)60145-9","volume":"37","author":"RE Hancock","year":"1995","unstructured":"Hancock, R. E., Fall, T., Brown, M. (1995). Cationic bactericidal peptides. Advance Microb Physiol. 37: 135\u2013175.","journal-title":"Advance Microb Physiol."},{"key":"15_CR21_15","unstructured":"National Committee for Clinical Laboratory Standards. (1997). Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically. Approved Standard M7-A4. National Committee for Clinical Standards, Wayne, Pennsyvania, USA."},{"key":"15_CR22_15","first-page":"1","volume":"1442","author":"K Matsuzaki","year":"1999","unstructured":"Matsuzaki, K. (1999) Why and how peptide-lipid interactions utilized for self-defense?. Magainins and tachyplesins as archetypes. Biochim Biophys Acta 1442: 1\u201310.","journal-title":"Magainins and tachyplesins as archetypes. Biochim Biophys Acta"},{"key":"15_CR23_15","doi-asserted-by":"publisher","first-page":"3165","DOI":"10.1210\/en.2003-1698","volume":"145","author":"S Yenugu","year":"2004","unstructured":"Yenugu, S., Hamil, K. G., Radhakrishnan, Y., French, F. S., Hall, S. H. (2004) The androgen regulated epididymal sperm-binding protein, ESC42, Is an antimicrobial beta-defensin. Endocrinol. 145: 3165\u20133173.","journal-title":"Endocrinol."},{"key":"15_CR24_15","doi-asserted-by":"publisher","first-page":"3435","DOI":"10.1128\/AAC.49.8.3435-3441.2005","volume":"49","author":"E Kugelberg","year":"2005","unstructured":"Kugelberg, E., Norstrom, T., Petersen, T. K., Duvold, T., Andersson, D. I., Hughes, D. (2005) Establishment of a superficial skin infection model in mice by using Staphylococcus aureus and Streptococcus pyogenes. Antimicrob Agents Chemother. 49: 3435\u20133441.","journal-title":"Antimicrob Agents Chemother."},{"key":"15_CR25_15","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1038\/35106587","volume":"414","author":"V Nizet","year":"2001","unstructured":"Nizet, V., Ohtake, T., Lauth, X., Trowbridge, J., Rudisill, J., Dorschner, R.A. (2001) Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature 414: 454\u2013457.","journal-title":"Nature"},{"key":"15_CR26_15","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1093\/jac\/dki125","volume":"55","author":"B Godin","year":"2005","unstructured":"Godin, B., Touitou, E., Rubinstein, E., Athamna, A., Athamna, M. (2005) A new approach for treatment of deep skin infections by an ethosomal antibiotic preparation: an in vivo study. J Antimicrob Chemother. 55: 989\u2013994.","journal-title":"J Antimicrob Chemother."},{"key":"15_CR27_15","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1093\/jac\/25.suppl_B.7","volume":"25","author":"M Faber","year":"1990","unstructured":"Faber, M., Rosdahl, V.T. (1990) Susceptibility to fusidic acid among Danish Staphylococcus aureus strains and fusidic add consumption. J Antimicrob Chemother 25: 7\u201314.","journal-title":"J Antimic Chemother"},{"key":"15_CR28_15","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1136\/bmj.324.7331.203","volume":"324","author":"S Koning","year":"2002","unstructured":"Koning, S., van Suijlekom-Smit, L. W. A., Nouwen, J. L., Verduin, C. M., Bernsen, R. M. D., Oranje, A. P., Thomas, S., van der Wouden, J. C. (2002) Fusidic acid cream in the treatment of impetigo in general practice: double blind randomized placebo controlled trial. BMJ. 324: 203\u2013206.","journal-title":"BMJ"},{"key":"15_CR29_15","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1016\/S0300-9084(01)01282-2","volume":"83","author":"VM Rodrigues","year":"2001","unstructured":"Rodrigues, V. M., Soares, A. M., Andriao-Escarso, S. H., Franceschi, A. M., Rucavado, A., Gutierrez, J. M. (2001) Pathological alterations induced by neuwiedase, a metalloproteinase isolated from Bothrops neuwiedi snake venom. Biochimie. 83: 471\u2013479.","journal-title":"Biochimie"},{"key":"15_CR30_15","doi-asserted-by":"publisher","first-page":"851","DOI":"10.1016\/j.toxicon.2004.08.021","volume":"44","author":"G D\u2019Suzea","year":"2004","unstructured":"D\u2019Suzea, G., Salazarb, V., D\u0131aza, P., Sevcika, C., Azpuruac, H., Bracho, N. (2004) Histopha\u00adtological changes and inflammatory response induced by Tityus discrepans scorpion venom in rams. Toxicon. 44: 851\u2013860.","journal-title":"Toxicon"},{"key":"15_CR31_15","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1159\/000095867","volume":"220","author":"M Pache","year":"2006","unstructured":"Pache, M., Meyer, P. (2006) Morphological changes of the retrobulbar optic nerve and its meningeal sheaths in glaucoma. Opthalmologica. 220: 393\u2013396.","journal-title":"Opthalmologica"},{"key":"15_CR32_15","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1007\/s00441-008-0591-y","volume":"332","author":"DF Egging","year":"2008","unstructured":"Egging, D. F., van Vlijmen-Willems, I., Choi, J., Peeters, A. C. T. M., van Rens, D., Veit, G., Koch, M., Davis, E. C., Schalkwijk, J. (2008) Analysis of obstetric complications and uterine connective tissue in tenascin-X-deficient humans and mice. Cell Tissue Res. 332: 523\u2013532.","journal-title":"Cell Tissue Res."}],"container-title":["Methods in Molecular Biology","Drug Design and Discovery"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-61779-012-6_15.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,18]],"date-time":"2021-11-18T18:12:32Z","timestamp":1637259152000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-1-61779-012-6_15"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011]]},"ISBN":["9781617790119","9781617790126"],"references-count":32,"URL":"https:\/\/doi.org\/10.1007\/978-1-61779-012-6_15","relation":{"is-part-of":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1007\/978-1-61779-012-6","asserted-by":"object"}]},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"value":"1064-3745","type":"print"},{"value":"1940-6029","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011]]}}}