{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T22:58:10Z","timestamp":1743029890672,"version":"3.40.3"},"publisher-location":"Totowa, NJ","reference-count":46,"publisher":"Humana Press","isbn-type":[{"type":"print","value":"9781617797668"},{"type":"electronic","value":"9781617797675"}],"license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012]]},"DOI":"10.1007\/978-1-61779-767-5_22","type":"book-chapter","created":{"date-parts":[[2012,3,27]],"date-time":"2012-03-27T16:33:44Z","timestamp":1332866024000},"page":"349-362","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Using Mini-genes to Identify Factors That Modulate Alternative Splicing"],"prefix":"10.1007","author":[{"given":"Robert","family":"Morse","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrian G.","family":"Todd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip J.","family":"Young","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,2,24]]},"reference":[{"key":"22_CR1_22","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1038\/nsb887","volume":"10","author":"L Cartegni","year":"2003","unstructured":"Cartegni L, Krainer AR (2003) Correction of disease-associated exon skipping by synthetic exon-specific activators. Nat Struct Biol 10:120\u2013125","journal-title":"Nat Struct Biol"},{"key":"22_CR2_22","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1016\/S0955-0674(00)00212-X","volume":"13","author":"ML Hastings","year":"2001","unstructured":"Hastings ML, Krainer AR (2001) Pre-mRNA splicing in the new millennium. Curr Opin Cell Biol 13:302\u2013309","journal-title":"Curr Opin Cell Biol"},{"key":"22_CR3_22","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1093\/hmg\/ddl449","volume":"16","author":"AJ Law","year":"2007","unstructured":"Law AJ, Kleinman JE, Weinberger DR, Weickert CS (2007) Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia. Hum Mol Genet 16:129\u2013141","journal-title":"Hum Mol Genet"},{"key":"22_CR4_22","doi-asserted-by":"publisher","first-page":"2779","DOI":"10.1093\/hmg\/ddi311","volume":"14","author":"A Matsuda","year":"2005","unstructured":"Matsuda A, Hirota T, Akahoshi M, Shimizu M, Tamari M, Miyatake A, Takahashi A, Nakashima K, Takahashi N, Obara K et al (2005) Coding SNP in tenascin-C Fn-III-D domain associates with adult asthma. Hum Mol Genet 14:2779\u20132786","journal-title":"Hum Mol Genet"},{"key":"22_CR5_22","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1093\/hmg\/ddg131","volume":"12","author":"F Pagani","year":"2003","unstructured":"Pagani F, Stuani C, Tzetis M, Kanavakis E, Efthymiadou A, Doudounakis S, Casals T, Baralle FE (2003) New type of disease causing mutations: the example of the composite exonic regulatory elements of splicing in CFTR exon 12. Hum Mol Genet 12:1111\u20131120","journal-title":"Hum Mol Genet"},{"key":"22_CR6_22","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1093\/hmg\/ddi151","volume":"14","author":"M Pele","year":"2005","unstructured":"Pele M, Tiret L, Kessler JL, Blot S, Panthier JJ (2005) SINE exonic insertion in the PTPLA gene leads to multiple splicing defects and segregates with the autosomal recessive centronuclear myopathy in dogs. Hum Mol Genet 14:1417\u20131427","journal-title":"Hum Mol Genet"},{"key":"22_CR7_22","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.1093\/hmg\/ddn439","volume":"18","author":"SA Shabalina","year":"2009","unstructured":"Shabalina SA, Zaykin DV, Gris P, Ogurtsov AY, Gauthier J, Shibata K, Tchivileva IE, Belfer I, Mishra B, Kiselycznyk C et al (2009) Expansion of the human mu-opioid receptor gene architecture: novel functional variants. Hum Mol Genet 18:1037\u20131051","journal-title":"Hum Mol Genet"},{"key":"22_CR8_22","doi-asserted-by":"publisher","first-page":"2919","DOI":"10.1093\/hmg\/ddi323","volume":"14","author":"M Shimizu","year":"2005","unstructured":"Shimizu M, Matsuda A, Yanagisawa K, Hirota T, Akahoshi M, Inomata N, Ebe K, Tanaka K, Sugiura H, Nakashima K et al (2005) Functional SNPs in the distal promoter of the ST2 gene are associated with atopic dermatitis. Hum Mol Genet 14:2919\u20132927","journal-title":"Hum Mol Genet"},{"key":"22_CR9_22","doi-asserted-by":"publisher","first-page":"2121","DOI":"10.1093\/hmg\/ddg222","volume":"12","author":"Y Yang","year":"2003","unstructured":"Yang Y, Swaminathan S, Martin BK, Sharan SK (2003) Aberrant splicing induced by missense mutations in BRCA1: clues from a humanized mouse model. Hum Mol Genet 12:2121\u20132131","journal-title":"Hum Mol Genet"},{"key":"22_CR10_22","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1093\/hmg\/11.5.577","volume":"11","author":"PJ Young","year":"2002","unstructured":"Young PJ, DiDonato CJ, Hu D, Kothary R, Androphy EJ, Lorson CL (2002) SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1. Hum Mol Genet 11:577\u2013587","journal-title":"Hum Mol Genet"},{"key":"22_CR11_22","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1093\/hmg\/ddm365","volume":"17","author":"F Zou","year":"2008","unstructured":"Zou F, Gopalraj RK, Lok J, Zhu H, Ling IF, Simpson JF, Tucker HM, Kelly JF, Younkin SG, Dickson DW et al (2008) Sex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer\u2019s disease. Hum Mol Genet 17:929\u2013935","journal-title":"Hum Mol Genet"},{"key":"22_CR12_22","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1002\/humu.20135","volume":"25","author":"P Griseri","year":"2005","unstructured":"Griseri P, Bachetti T, Puppo F, Lantieri F, Ravazzolo R, Devoto M, Ceccherini I (2005) A common haplotype at the 5\u2032 end of the RET proto-oncogene, overrepresented in Hirschsprung patients, is associated with reduced gene expression. Hum Mutat 25:189\u2013195","journal-title":"Hum Mutat"},{"key":"22_CR13_22","doi-asserted-by":"publisher","first-page":"6307","DOI":"10.1073\/pnas.96.11.6307","volume":"96","author":"CL Lorson","year":"1999","unstructured":"Lorson CL, Hahnen E, Androphy EJ, Wirth B (1999) A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy. Proc Natl Acad Sci USA 96:6307\u20136311","journal-title":"Proc Natl Acad Sci USA"},{"key":"22_CR14_22","doi-asserted-by":"publisher","first-page":"9618","DOI":"10.1073\/pnas.160181697","volume":"97","author":"Y Hofmann","year":"2000","unstructured":"Hofmann Y, Lorson CL, Stamm S, Androphy EJ, Wirth B (2000) Htra2-beta 1 stimulates an exonic splicing enhancer and can restore full-length SMN expression to survival motor neuron 2 (SMN2). Proc Natl Acad Sci USA 97:9618\u20139623","journal-title":"Proc Natl Acad Sci USA"},{"key":"22_CR15_22","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1093\/hmg\/9.2.259","volume":"9","author":"CL Lorson","year":"2000","unstructured":"Lorson CL, Androphy EJ (2000) An exonic enhancer is required for inclusion of an essential exon in the SMA-determining gene SMN. Hum Mol Genet 9:259\u2013265","journal-title":"Hum Mol Genet"},{"key":"22_CR16_22","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/0092-8674(95)90460-3","volume":"80","author":"S Lefebvre","year":"1995","unstructured":"Lefebvre S, Burglen L, Reboullet S, Clermont O, Burlet P, Viollet L, Benichou B, Cruaud C, Millasseau P, Zeviani M (1995) Identification and characterization of a spinal muscular atrophy-determining gene. Cell 80:155\u2013165","journal-title":"Cell"},{"key":"22_CR17_22","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1006\/nbdi.1996.0010","volume":"3","author":"TO Crawford","year":"1996","unstructured":"Crawford TO, Pardo CA (1996) The neurobiology of childhood spinal muscular atrophy. Neurobiol Dis 3:97\u2013110","journal-title":"Neurobiol Dis"},{"key":"22_CR18_22","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1038\/nrn2670","volume":"10","author":"AH Burghes","year":"2009","unstructured":"Burghes AH, Beattie CE (2009) Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick? Nat Rev Neurosci 10:597\u2013609","journal-title":"Nat Rev Neurosci"},{"key":"22_CR19_22","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/s00401-008-0411-1","volume":"116","author":"G Simic","year":"2008","unstructured":"Simic G (2008) Pathogenesis of proximal autosomal recessive spinal muscular atrophy. Acta Neuropathol 116:223\u2013234","journal-title":"Acta Neuropathol"},{"key":"22_CR20_22","doi-asserted-by":"publisher","first-page":"4906","DOI":"10.1093\/hmg\/ddq425","volume":"19","author":"FM Jodelka","year":"2010","unstructured":"Jodelka FM, Ebert AD, Duelli DM, Hastings ML (2010) A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2. Hum Mol Genet 19:4906\u201317","journal-title":"Hum Mol Genet"},{"key":"22_CR21_22","doi-asserted-by":"publisher","first-page":"1712","DOI":"10.1086\/302160","volume":"63","author":"DW Parsons","year":"1998","unstructured":"Parsons DW, McAndrew PE, Iannaccone ST, Mendell JR, Burghes AH, Prior TW (1998) Intragenic telSMN mutations: frequency, distribution, evidence of a founder effect, and modification of the spinal muscular atrophy phenotype by cenSMN copy number. Am J Hum Genet 63:1712\u20131723","journal-title":"Am J Hum Genet"},{"key":"22_CR22_22","doi-asserted-by":"publisher","first-page":"1102","DOI":"10.1086\/301608","volume":"61","author":"B Wirth","year":"1997","unstructured":"Wirth B, Schmidt T, Hahnen E, Rudnik-Sch\u00f6neborn S, Krawczak M, M\u00fcller-Myhsok B, Sch\u00f6nling J, Zerres K (1997) De novo rearrangements found in 2% of index patients with spinal muscular atrophy: mutational mechanisms, parental origin, mutation rate, and implications for genetic counseling. Am J Hum Genet 61:1102\u20131111","journal-title":"Am J Hum Genet"},{"key":"22_CR23_22","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1016\/S0960-8966(97)00450-1","volume":"7","author":"K Talbot","year":"1997","unstructured":"Talbot K, Rodrigues NR, Ignatius J, Muntoni F, Davies KE (1997) Gene conversion at the SMN locus in autosomal recessive spinal muscular atrophy does not predict a mild phenotype. Neuromuscul Disord 7:198\u2013201","journal-title":"Neuromuscul Disord"},{"key":"22_CR24_22","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1093\/hmg\/6.3.497","volume":"6","author":"K Talbot","year":"1997","unstructured":"Talbot K, Ponting CP, Theodosiou AM, Rodrigues NR, Surtees R, Mountford R, Davies KE (1997) Missense mutation clustering in the survival motor neuron gene: a role for a conserved tyrosine and glycine rich region of the protein in RNA metabolism? Hum Mol Genet 6:497\u2013500","journal-title":"Hum Mol Genet"},{"key":"22_CR25_22","doi-asserted-by":"publisher","first-page":"1411","DOI":"10.1086\/515465","volume":"60","author":"PE McAndrew","year":"1997","unstructured":"McAndrew PE, Parsons DW, Simard LR, Rochette C, Ray PN, Mendell JR, Prior TW, Burghes AH (1997) Identification of proximal spinal muscular atrophy carriers and patients by analysis of SMNT and SMNC gene copy number. Am J Hum Genet 60:1411\u20131422","journal-title":"Am J Hum Genet"},{"key":"22_CR26_22","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1086\/513886","volume":"61","author":"L Campbell","year":"1997","unstructured":"Campbell L, Potter A, Ignatius J, Dubowitz V, Davies K (1997) Genomic variation and gene conversion in spinal muscular atrophy: implications for disease process and clinical phenotype. Am J Hum Genet 61:40\u201350","journal-title":"Am J Hum Genet"},{"key":"22_CR27_22","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1093\/hmg\/5.3.359","volume":"5","author":"CH Wang","year":"1996","unstructured":"Wang CH, Xu J, Carter TA, Ross BM, Dominski MK, Bellcross CA, Penchaszadeh GK, Munsat TL, Gilliam TC (1996) Characterization of survival motor neuron (SMNT) gene deletions in asymptomatic carriers of spinal muscular atrophy. Hum Mol Genet 5:359\u2013365","journal-title":"Hum Mol Genet"},{"key":"22_CR28_22","doi-asserted-by":"publisher","first-page":"1727","DOI":"10.1093\/hmg\/5.11.1727","volume":"5","author":"DW Parsons","year":"1996","unstructured":"Parsons DW, McAndrew PE, Monani UR, Mendell JR, Burghes AH, Prior TW (1996) An 11 base pair duplication in exon 6 of the SMN gene produces a type I spinal muscular atrophy (SMA) phenotype: further evidence for SMN as the primary SMA-determining gene. Hum Mol Genet 5:1727\u20131732","journal-title":"Hum Mol Genet"},{"key":"22_CR29_22","doi-asserted-by":"publisher","first-page":"1971","DOI":"10.1093\/hmg\/5.12.1971","volume":"5","author":"C Brahe","year":"1996","unstructured":"Brahe C, Clermont O, Zappata S, Tiziano F, Melki J, Neri G (1996) Frameshift mutation in the survival motor neuron gene in a severe case of SMA type I. Hum Mol Genet 5:1971\u20131976","journal-title":"Hum Mol Genet"},{"key":"22_CR30_22","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1093\/hmg\/7.10.1531","volume":"7","author":"S Lefebvre","year":"1998","unstructured":"Lefebvre S, Burglen L, Fr\u00e9zal J, Munnich A, Melki J (1998) The role of the SMN gene in proximal spinal muscular atrophy. Hum Mol Genet 7:1531\u20131536","journal-title":"Hum Mol Genet"},{"key":"22_CR31_22","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1038\/ng0797-265","volume":"16","author":"S Lefebvre","year":"1997","unstructured":"Lefebvre S, Burlet P, Liu Q, Bertrandy S, Clermont O, Munnich A, Dreyfuss G, Melki J (1997) Correlation between severity and SMN protein level in spinal muscular atrophy. Nat Genet 16:265\u2013269","journal-title":"Nat Genet"},{"key":"22_CR32_22","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1093\/hmg\/8.7.1177","volume":"8","author":"UR Monani","year":"1999","unstructured":"Monani UR, Lorson CL, Parsons DW, Prior TW, Androphy EJ, Burghes AH, McPherson JD (1999) A single nucleotide difference that alters splicing patterns distinguishes the SMA gene SMN1 from the copy gene SMN2. Hum Mol Genet 8:1177\u20131183","journal-title":"Hum Mol Genet"},{"key":"22_CR33_22","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1038\/ng0598-63","volume":"19","author":"CL Lorson","year":"1998","unstructured":"Lorson CL, Strasswimmer J, Yao JM, Baleja JD, Hahnen E, Wirth B, Le T, Burghes AH, Androphy EJ (1998) SMN oligomerization defect correlates with spinal muscular atrophy severity. Nat Genet 19:63\u201366","journal-title":"Nat Genet"},{"key":"22_CR34_22","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1261\/rna.1273209","volume":"15","author":"M Martins de Araujo","year":"2009","unstructured":"Martins de Araujo M, Bonnal S, Hastings ML, Krainer AR, Valcarcel J (2009) Differential 3\u2032 splice site recognition of SMN1 and SMN2 transcripts by U2AF and U2 snRNP. RNA 15:515\u2013523","journal-title":"RNA"},{"key":"22_CR35_22","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1086\/498853","volume":"78","author":"L Cartegni","year":"2006","unstructured":"Cartegni L, Hastings ML, Calarco JA, de Stanchina E, Krainer AR (2006) Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2. Am J Hum Genet 78:63\u201377","journal-title":"Am J Hum Genet"},{"key":"22_CR36_22","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1038\/ng854","volume":"30","author":"L Cartegni","year":"2002","unstructured":"Cartegni L, Krainer AR (2002) Disruption of an SF2\/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1. Nat Genet 30:377\u2013384","journal-title":"Nat Genet"},{"key":"22_CR37_22","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1016\/j.ajhg.2009.08.002","volume":"85","author":"TW Prior","year":"2009","unstructured":"Prior TW, Krainer AR, Hua Y, Swoboda KJ, Snyder PC, Bridgeman SJ, Burghes AH, Kissel JT (2009) A positive modifier of spinal muscular atrophy in the SMN2 gene. Am J Hum Genet 85:408\u2013413","journal-title":"Am J Hum Genet"},{"key":"22_CR38_22","doi-asserted-by":"publisher","first-page":"5797","DOI":"10.1073\/pnas.0801692105","volume":"105","author":"C Zhang","year":"2008","unstructured":"Zhang C, Li WH, Krainer AR, Zhang MQ (2008) RNA landscape of evolution for optimal exon and intron discrimination. Proc Natl Acad Sci USA 105:5797\u20135802","journal-title":"Proc Natl Acad Sci USA"},{"key":"22_CR39_22","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1046\/j.1469-1809.2000.6450375.x","volume":"64","author":"RJ Janssen","year":"2000","unstructured":"Janssen RJ, Wevers RA, Haussler M, Luyten JA, Steenbergen-Spanjers GC, Hoffmann GF, Nagatsu T, Van den Heuvel LP (2000) A branch site mutation leading to aberrant splicing of the human tyrosine hydroxylase gene in a child with a severe extrapyramidal movement disorder. Ann Hum Genet 64:375\u2013382","journal-title":"Ann Hum Genet"},{"key":"22_CR40_22","first-page":"586","volume":"3","author":"Q Wu","year":"1997","unstructured":"Wu Q, Krainer AR (1997) Splicing of a divergent subclass of AT-AC introns requires the major spliceosomal snRNAs. RNA 3:586\u2013601","journal-title":"RNA"},{"key":"22_CR41_22","doi-asserted-by":"publisher","first-page":"e538","DOI":"10.1371\/journal.pone.0000538","volume":"2","author":"ML Hastings","year":"2007","unstructured":"Hastings ML, Allemand E, Duelli DM, Myers MP, Krainer AR (2007) Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65). PLoS One 2:e538","journal-title":"PLoS One"},{"key":"22_CR42_22","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1083\/jcb.138.2.225","volume":"138","author":"JF Caceres","year":"1997","unstructured":"Caceres JF, Misteli T, Screaton GR, Spector DL, Krainer AR (1997) Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specificity. J Cell Biol 138:225\u2013238","journal-title":"J Cell Biol"},{"key":"22_CR43_22","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1083\/jcb.143.2.297","volume":"143","author":"T Misteli","year":"1998","unstructured":"Misteli T, Caceres JF, Clement JQ, Krainer AR, Wilkinson MF, Spector DL (1998) Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo. J Cell Biol 143:297\u2013307","journal-title":"J Cell Biol"},{"key":"22_CR44_22","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1038\/ng1207","volume":"34","author":"T Kashima","year":"2003","unstructured":"Kashima T, Manley JL (2003) A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy. Nat Genet 34:460\u2013463","journal-title":"Nat Genet"},{"key":"22_CR45_22","doi-asserted-by":"publisher","first-page":"3149","DOI":"10.1093\/hmg\/ddm276","volume":"16","author":"T Kashima","year":"2007","unstructured":"Kashima T, Rao N, David CJ, Manley JL (2007) hnRNP A1 functions with specificity in repression of SMN2 exon 7 splicing. Hum Mol Genet 16:3149\u20133159","journal-title":"Hum Mol Genet"},{"key":"22_CR46_22","doi-asserted-by":"publisher","first-page":"3426","DOI":"10.1073\/pnas.0700343104","volume":"104","author":"T Kashima","year":"2007","unstructured":"Kashima T, Rao N, Manley JL (2007) An intronic element contributes to splicing repression in spinal muscular atrophy. Proc Natl Acad Sci USA 104:3426\u20133431","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Methods in Molecular Biology","Exon Skipping"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-1-61779-767-5_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T22:27:50Z","timestamp":1675204070000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-1-61779-767-5_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012]]},"ISBN":["9781617797668","9781617797675"],"references-count":46,"URL":"https:\/\/doi.org\/10.1007\/978-1-61779-767-5_22","relation":{},"ISSN":["1064-3745","1940-6029"],"issn-type":[{"type":"print","value":"1064-3745"},{"type":"electronic","value":"1940-6029"}],"subject":[],"published":{"date-parts":[[2012]]},"assertion":[{"value":"24 February 2012","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}