{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T06:56:43Z","timestamp":1771657003035,"version":"3.50.1"},"publisher-location":"Cham","reference-count":215,"publisher":"Springer International Publishing","isbn-type":[{"value":"9783030151379","type":"print"},{"value":"9783030151386","type":"electronic"}],"license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019]]},"DOI":"10.1007\/978-3-030-15138-6_11","type":"book-chapter","created":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T14:10:00Z","timestamp":1558620600000},"page":"267-302","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Mechanisms of Inflammasome Signaling, microRNA Induction and Resolution of Inflammation by Helicobacter pylori"],"prefix":"10.1007","author":[{"given":"Suneesh Kumar","family":"Pachathundikandi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Blaser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steffen","family":"Backert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,5,24]]},"reference":[{"key":"11_CR1","doi-asserted-by":"publisher","first-page":"3706","DOI":"10.4049\/jimmunol.1200591","volume":"190","author":"CC Allison","year":"2013","unstructured":"Allison CC, Ferrand J, McLeod L, Hassan M, Kaparakis-Liaskos M, Grubman A, Bhathal PS, Dev A, Sievert W, Jenkins BJ, Ferrero RL (2013) Nucleotide oligomerization domain 1 enhances IFN-\u03b3 signaling in gastric epithelial cells during Helicobacter pylori infection and exacerbates disease severity. J Immunol 190:3706\u20133715. https:\/\/doi.org\/10.4049\/jimmunol.1200591","journal-title":"J Immunol"},{"key":"11_CR2","doi-asserted-by":"publisher","first-page":"4653","DOI":"10.1242\/dev.02073","volume":"132","author":"I Alvarez-Garcia","year":"2005","unstructured":"Alvarez-Garcia I, Miska EA (2005) MicroRNA functions in animal development and human disease. Development 132:4653\u20134662. https:\/\/doi.org\/10.1242\/dev.02073","journal-title":"Development"},{"key":"11_CR3","doi-asserted-by":"publisher","first-page":"1092","DOI":"10.1172\/jci27177","volume":"116","author":"A Amedei","year":"2006","unstructured":"Amedei A, Cappon A, Codolo G, Cabrelle A, Polenghi A, Benagiano M, Tasca E, Azzurri A, D\u2019Elios MM, Del Prete G, de Bernard M (2006) The neutrophil-activating protein of Helicobacter pylori promotes Th1 immune responses. J Clin Invest 116:1092\u20131101. https:\/\/doi.org\/10.1172\/jci27177","journal-title":"J Clin Invest"},{"key":"11_CR4","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1053\/j.gastro.2007.11.009","volume":"134","author":"MR Amieva","year":"2008","unstructured":"Amieva MR, El-Omar EM (2008) Host-bacterial interactions in Helicobacter pylori infection. Gastroenterology 134:306\u2013323. https:\/\/doi.org\/10.1053\/j.gastro.2007.11.009","journal-title":"Gastroenterology"},{"key":"11_CR5","doi-asserted-by":"publisher","first-page":"9247","DOI":"10.1073\/pnas.0502040102","volume":"102","author":"E Andersen-Nissen","year":"2005","unstructured":"Andersen-Nissen E, Smith KD, Strobe KL, Barrett SLR, Cookson BT, Logan SM, Aderem A (2005) Evasion of Toll-like receptor 5 by flagellated bacteria. Proc Natl Acad Sci USA 102:9247\u20139252. https:\/\/doi.org\/10.1073\/pnas.0502040102","journal-title":"Proc Natl Acad Sci USA"},{"key":"11_CR6","doi-asserted-by":"publisher","first-page":"2367","DOI":"10.1002\/ijc.24219","volume":"124","author":"T Ando","year":"2009","unstructured":"Ando T, Yoshida T, Enomoto S, Asada K, Tatematsu M, Ichinose M, Sugiyama T, Ushijima T (2009) DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: its possible involvement in the formation of epigenetic field defect. Int J Cancer 124:2367\u20132374. https:\/\/doi.org\/10.1002\/ijc.24219","journal-title":"Int J Cancer"},{"key":"11_CR7","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1111\/j.0105-2896.2004.00202.x","volume":"202","author":"E Andreakos","year":"2004","unstructured":"Andreakos E, Foxwell B, Feldmann M (2004) Is targeting Toll-like receptors and their signaling pathway a useful therapeutic approach to modulating cytokine-driven inflammation? Immunol Rev 202:250\u2013265. https:\/\/doi.org\/10.1111\/j.0105-2896.2004.00202.x","journal-title":"Immunol Rev"},{"key":"11_CR8","doi-asserted-by":"publisher","first-page":"3860","DOI":"10.1016\/j.celrep.2017.12.015","volume":"21","author":"IC Arnold","year":"2017","unstructured":"Arnold IC, Zhang X, Urban S, Artola-Bor\u00e1n M, Manz MG, Ottemann KM, M\u00fcller A (2017) NLRP3 controls the development of gastrointestinal CD11b+ dendritic cells in the steady state and during chronic bacterial infection. Cell Reports 21:3860\u20133872. https:\/\/doi.org\/10.1016\/j.celrep.2017.12.015","journal-title":"Cell Reports"},{"key":"11_CR9","doi-asserted-by":"publisher","first-page":"2475","DOI":"10.1172\/jci38605","volume":"119","author":"JC Atherton","year":"2009","unstructured":"Atherton JC, Blaser MJ (2009) Coadaptation of Helicobacter pylori and humans: ancient history, modern implications. J Clin Invest 119:2475\u20132487. https:\/\/doi.org\/10.1172\/jci38605","journal-title":"J Clin Invest"},{"issue":"2","key":"11_CR10","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.tibs.2007.10.006","volume":"33","author":"S Backert","year":"2008","unstructured":"Backert S, Feller SM, Wessler S (2008) Emerging roles of Abl family tyrosine kinases in microbial pathogenesis. Trends Biochem Sci 33(2):80\u201390. https:\/\/doi.org\/10.1016\/j.tibs.2007.10.006","journal-title":"Trends Biochem Sci"},{"key":"11_CR11","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/j.tim.2010.08.003","volume":"18","author":"S Backert","year":"2010","unstructured":"Backert S, Naumann M (2010) What a disorder: proinflammatory signaling pathways induced by Helicobacter pylori. Trends Microbiol 18:479\u2013486. https:\/\/doi.org\/10.1016\/j.tim.2010.08.003","journal-title":"Trends Microbiol"},{"issue":"6","key":"11_CR12","doi-asserted-by":"publisher","first-page":"955","DOI":"10.2217\/fmb.15.32","volume":"10","author":"S Backert","year":"2015","unstructured":"Backert S, Tegtmeyer N, Fischer W (2015) Composition, structure and function of the Helicobacter pylori cag pathogenicity island encoded type IV secretion system. Future Microbiol 10(6):955\u2013965. https:\/\/doi.org\/10.2217\/fmb.15.32","journal-title":"Future Microbiol"},{"key":"11_CR13","doi-asserted-by":"publisher","first-page":"1715","DOI":"10.1084\/jem.20051782","volume":"202","author":"A Bafica","year":"2005","unstructured":"Bafica A, Scanga CA, Feng CG, Leifer C, Cheever A, Sher A (2005) TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis. J Exp Med 202:1715\u20131724. https:\/\/doi.org\/10.1084\/jem.20051782","journal-title":"J Exp Med"},{"key":"11_CR14","doi-asserted-by":"publisher","first-page":"5823","DOI":"10.1074\/jbc.m110.192393","volume":"286","author":"K Bansal","year":"2011","unstructured":"Bansal K, Balaji KN (2011) Intracellular pathogen sensor NOD2 programs macrophages to trigger notch1 activation. J Biol Chem 286:5823\u20135835. https:\/\/doi.org\/10.1074\/jbc.m110.192393","journal-title":"J Biol Chem"},{"key":"11_CR15","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.1053\/j.gastro.2016.08.014","volume":"151","author":"RM Barrozo","year":"2016","unstructured":"Barrozo RM, Hansen LM, Lam AM, Skoog EC, Martin ME, Cai LP, Lin Y, Latoscha A, Suerbaum S, Canfield DR, Solnick JV (2016) CagY is an immune-sensitive regulator of the Helicobacter pylori type IV secretion system. Gastroenterology 151:1164\u20131175.e3. https:\/\/doi.org\/10.1053\/j.gastro.2016.08.014","journal-title":"Gastroenterology"},{"key":"11_CR16","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1007\/BF02592984","volume":"26","author":"D Basso","year":"1996","unstructured":"Basso D, Scrigner M, Toma A, Navaglia F, Di Mario F, Rugge M, Plebani M (1996) Helicobacter pylori infection enhances mucosal interleukin-1 beta, interleukin-6, and the soluble receptor of interleukin-2. Int J Clin Lab Res 26:207\u2013210","journal-title":"Int J Clin Lab Res"},{"key":"11_CR17","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1046\/j.1365-2249.1999.00968.x","volume":"117","author":"J Bauditz","year":"1999","unstructured":"Bauditz J, Ortner M, Bierbaum M, Niedobitek G, Lochs H, Schreiber S (1999) Production of IL-12 in gastritis relates to infection with Helicobacter pylori. Clin Exp Immunol 117:316\u2013323","journal-title":"Clin Exp Immunol"},{"key":"11_CR18","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1038\/mi.2016.60","volume":"10","author":"S Beceiro","year":"2017","unstructured":"Beceiro S, Radin JN, Chatuvedi R, Piazuelo MB, Horvarth DJ, Cortado H, Gu Y, Dixon B, Gu C, Lange I, Koomoa D-L, Wilson KT, Algood HMS, Partida-S\u00e1nchez S (2017) TRPM2 ion channels regulate macrophage polarization and gastric inflammation during Helicobacter pylori infection. Mucosal Immunol 10:493\u2013507. https:\/\/doi.org\/10.1038\/mi.2016.60","journal-title":"Mucosal Immunol"},{"key":"11_CR19","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1182\/blood-2008-07-019307","volume":"113","author":"BA Beutler","year":"2008","unstructured":"Beutler BA (2008) TLRs and innate immunity. Blood 113:1399\u20131407. https:\/\/doi.org\/10.1182\/blood-2008-07-019307","journal-title":"Blood"},{"key":"11_CR20","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1111\/j.1574-695x.1993.tb00344.x","volume":"6","author":"S Birkholz","year":"1993","unstructured":"Birkholz S, Knipp U, Nietzki C, Adamek RJ, Opferkuch W (1993) Immunological activity of lipopolysaccharide of Helicobacter pylori on human peripheral mononuclear blood cells in comparison to lipopolysaccharides of other intestinal bacteria. FEMS Immunol Med Microbiol 6:317\u2013324. https:\/\/doi.org\/10.1111\/j.1574-695x.1993.tb00344.x","journal-title":"FEMS Immunol Med Microbiol"},{"key":"11_CR21","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1136\/jcp.54.4.285","volume":"54","author":"K Bodger","year":"2001","unstructured":"Bodger K, Bromelow K, Wyatt JI, Heatley RV (2001) Interleukin 10 in Helicobacter pylori associated gastritis: immunohistochemical localisation and in vitro effects on cytokine secretion. J Clin Pathol 54:285\u2013292","journal-title":"J Clin Pathol"},{"key":"11_CR22","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1038\/mi.2016.131","volume":"10","author":"KM Brawner","year":"2017","unstructured":"Brawner KM, Kumar R, Serrano CA, Ptacek T, Lefkowitz E, Morrow CD, Zhi D, Kyanam-Kabir-Baig KR, Smythies LE, Harris PR, Smith PD (2017) Helicobacter pylori infection is associated with an altered gastric microbiota in children. Mucosal Immunol 10:1169\u20131177. https:\/\/doi.org\/10.1038\/mi.2016.131","journal-title":"Mucosal Immunol"},{"issue":"1","key":"11_CR23","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.femsle.2005.06.008","volume":"249","author":"M Brisslert","year":"2005","unstructured":"Brisslert M, Enarsson K, Lundin S, Karlsson A, Kusters JG, Svennerholm AM, Backert S, Quiding-J\u00e4rbrink M (2005) Helicobacter pylori induce neutrophil transendothelial migration: role of the bacterial HP-NAP. FEMS Microbiol Lett 249(1):95\u2013103","journal-title":"FEMS Microbiol Lett"},{"key":"11_CR24","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1038\/nrmicro2266","volume":"8","author":"CE Bryant","year":"2010","unstructured":"Bryant CE, Spring DR, Gangloff M, Gay NJ (2010) The molecular basis of the host response to lipopolysaccharide. Nat Rev Microbiol 8:8\u201314. https:\/\/doi.org\/10.1038\/nrmicro2266","journal-title":"Nat Rev Microbiol"},{"key":"11_CR25","doi-asserted-by":"publisher","first-page":"1424","DOI":"10.3748\/wjg.v20.i6.1424","volume":"20","author":"ACT Cadamuro","year":"2014","unstructured":"Cadamuro ACT, Rossi AFT, Maniezzo NM, Silva AE (2014) Helicobacter pylori infection: host immune response, implications on gene expression and microRNAs. World J Gastroenterol 20:1424\u20131437. https:\/\/doi.org\/10.3748\/wjg.v20.i6.1424","journal-title":"World J Gastroenterol"},{"key":"11_CR26","doi-asserted-by":"publisher","first-page":"e01243","DOI":"10.1128\/mbio.01243-14","volume":"5","author":"A Carbo","year":"2014","unstructured":"Carbo A, Olivares-Villag\u00f3mez D, Hontecillas R, Bassaganya-Riera J, Chaturvedi R, Piazuelo MB, Delgado A, Washington MK, Wilson KT, Algood HMS (2014) Systems modeling of the role of interleukin-21 in the maintenance of effector CD4+ T cell responses during chronic Helicobacter pylori infection. MBio 5:e01243\u2013e01214. https:\/\/doi.org\/10.1128\/mbio.01243-14","journal-title":"MBio"},{"key":"11_CR27","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1002\/eji.200737635","volume":"38","author":"R Caruso","year":"2008","unstructured":"Caruso R, Fina D, Paoluzi OA, Del Vecchio Blanco G, Stolfi C, Rizzo A, Caprioli F, Sarra M, Andrei F, Fantini MC, MacDonald TT, Pallone F, Monteleone G (2008) IL-23-mediated regulation of IL-17 production in Helicobacter pylori-infected gastric mucosa. Eur J Immunol 38:470\u2013478. https:\/\/doi.org\/10.1002\/eji.200737635","journal-title":"Eur J Immunol"},{"key":"11_CR28","doi-asserted-by":"publisher","first-page":"5957","DOI":"10.4049\/jimmunol.178.9.5957","volume":"178","author":"R Caruso","year":"2007","unstructured":"Caruso R, Fina D, Peluso I, Fantini MC, Tosti C, Del Vecchio Blanco G, Paoluzi OA, Caprioli F, Andrei F, Stolfi C, Romano M, Ricci V, MacDonald TT, Pallone F, Monteleone G (2007) IL-21 is highly produced in Helicobacter pylori-infected gastric mucosa and promotes gelatinases synthesis. J Immunol 178:5957\u20135965","journal-title":"J Immunol"},{"key":"11_CR29","doi-asserted-by":"publisher","first-page":"188","DOI":"10.5009\/gnl13371","volume":"9","author":"H Chang","year":"2015","unstructured":"Chang H, Kim N, Park JH, Nam RH, Choi YJ, Lee HS, Yoon H, Shin CM, Park YS, Kim JM, Lee DH (2015a) Different microRNA expression levels in gastric cancer depending on Helicobacter pylori infection. Gut Liver 9:188\u2013196. https:\/\/doi.org\/10.5009\/gnl13371","journal-title":"Gut Liver"},{"key":"11_CR30","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1111\/hel.12220","volume":"20","author":"H Chang","year":"2015","unstructured":"Chang H, Kim N, Park JH, Nam RH, Choi YJ, Park SM, Choi YJ, Yoon H, Shin CM, Lee DH (2015b) Helicobacter pylori might induce TGF-\u03b21-mediated EMT by means of cagE. Helicobacter 20:438\u2013448. https:\/\/doi.org\/10.1111\/hel.12220","journal-title":"Helicobacter"},{"key":"11_CR31","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1007\/s00253-012-4034-z","volume":"96","author":"L-L Chang","year":"2012","unstructured":"Chang L-L, Wang S-W, Wu I-C, Yu F-J, Su Y-C, Chen Y-P, Wu D-C, Kuo C-H, Hung C-H (2012) Impaired dendritic cell maturation and IL-10 production following H. pylori stimulation in gastric cancer patients. Appl Microbiol Biotechnol 96:211\u2013220. https:\/\/doi.org\/10.1007\/s00253-012-4034-z","journal-title":"Appl Microbiol Biotechnol"},{"key":"11_CR32","doi-asserted-by":"publisher","first-page":"e58514","DOI":"10.1371\/journal.pone.0058514","volume":"8","author":"P Chattoraj","year":"2013","unstructured":"Chattoraj P, Yang Q, Khandai A, Al-Hendy O, Ismail N (2013) TLR2 and Nod2 mediate resistance or susceptibility to fatal intracellular Ehrlichia infection in murine models of ehrlichiosis. PLoS ONE 8:e58514. https:\/\/doi.org\/10.1371\/journal.pone.0058514","journal-title":"PLoS ONE"},{"key":"11_CR33","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.bbrc.2017.01.110","volume":"484","author":"G Chen","year":"2017","unstructured":"Chen G, Tang N, Wang C, Xiao L, Yu M, Zhao L, Cai H, Han L, Xie C, Zhang Y (2017) TNF-\u03b1-inducing protein of Helicobacter pylori induces epithelial-mesenchymal transition (EMT) in gastric cancer cells through activation of IL-6\/STAT3 signaling pathway. Biochem Biophys Res Commun 484:311\u2013317. https:\/\/doi.org\/10.1016\/j.bbrc.2017.01.110","journal-title":"Biochem Biophys Res Commun"},{"key":"11_CR34","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1046\/j.1440-1746.2001.02459.x","volume":"16","author":"W Chen","year":"2001","unstructured":"Chen W, Shu D, Chadwick VS (2001) Helicobacter pylori infection: mechanism of colonization and functional dyspepsia Reduced colonization of gastric mucosa by Helicobacter pylori in mice deficient in interleukin-10. J Gastroenterol Hepatol 16:377\u2013383","journal-title":"J Gastroenterol Hepatol"},{"key":"11_CR35","first-page":"607","volume":"19","author":"SF Cheng","year":"2015","unstructured":"Cheng SF, Li L, Wang LM (2015) miR-155 and miR-146b negatively regulates IL6 in Helicobacter pylori (cagA+) infected gastroduodenal ulcer. Eur Rev Med Pharmacol Sci 19:607\u2013613","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"11_CR36","doi-asserted-by":"publisher","first-page":"392","DOI":"10.5009\/gnl16265","volume":"11","author":"J-W Chung","year":"2017","unstructured":"Chung J-W, Jeong SH, Lee SM, Pak JH, Lee GH, Jeong J-Y, Kim J-H (2017) Expression of microRNA in host cells infected with Helicobacter pylori. Gut Liver 11:392\u2013400. https:\/\/doi.org\/10.5009\/gnl16265","journal-title":"Gut Liver"},{"key":"11_CR37","doi-asserted-by":"publisher","first-page":"1550","DOI":"10.1136\/gutjnl-2013-306253","volume":"63","author":"KW Cook","year":"2014","unstructured":"Cook KW, Letley DP, Ingram RJM, Staples E, Skjoldmose H, Atherton JC, Robinson K (2014) CCL20\/CCR6-mediated migration of regulatory T cells to the Helicobacter pylori-infected human gastric mucosa. Gut 63:1550\u20131559. https:\/\/doi.org\/10.1136\/gutjnl-2013-306253","journal-title":"Gut"},{"key":"11_CR38","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1038\/nm.2069","volume":"16","author":"R Cooney","year":"2010","unstructured":"Cooney R, Baker J, Brain O, Danis B, Pichulik T, Allan P, Ferguson DJP, Campbell BJ, Jewell D, Simmons A (2010) NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med 16:90\u201397. https:\/\/doi.org\/10.1038\/nm.2069","journal-title":"Nat Med"},{"key":"11_CR39","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1186\/s12879-018-3368-2","volume":"18","author":"AC Cort\u00e9s-M\u00e1rquez","year":"2018","unstructured":"Cort\u00e9s-M\u00e1rquez AC, Mendoza-Elizalde S, Arenas-Huertero F, Trillo-Tinoco J, Valencia-Mayoral P, Consuelo-S\u00e1nchez A, Zarate-Franco J, Dionicio-Avenda\u00f1o AR, de Jes\u00fas Herrera-Esquivel J, Recinos-Carrera EG, Col\u00edn-Valverde C, Rivera-Guti\u00e9rrez S, Reyes-L\u00f3pez A, Vigueras-Galindo JC, Vel\u00e1zquez-Guadarrama N (2018) Differential expression of miRNA-146a and miRNA-155 in gastritis induced by Helicobacter pylori infection in paediatric patients, adults, and an animal model. BMC Infect Dis 18:463. https:\/\/doi.org\/10.1186\/s12879-018-3368-2","journal-title":"BMC Infect Dis"},{"key":"11_CR40","doi-asserted-by":"publisher","first-page":"e1002454","DOI":"10.1371\/journal.ppat.1002454","volume":"7","author":"TW Cullen","year":"2011","unstructured":"Cullen TW, Giles DK, Wolf LN, Ecobichon C, Boneca IG, Trent MS (2011) Helicobacter pylori versus the host: remodeling of the bacterial outer membrane is required for survival in the gastric mucosa. PLoS Pathog 7:e1002454. https:\/\/doi.org\/10.1371\/journal.ppat.1002454","journal-title":"PLoS Pathog"},{"key":"11_CR41","doi-asserted-by":"publisher","first-page":"e12859","DOI":"10.1111\/cmi.12859","volume":"20","author":"C Datta","year":"2018","unstructured":"Datta C, Subuddhi A, Kumar M, Lepcha TT, Chakraborty S, Jana K, Ghosh Z, Mukhopadhyay AK, Basu J, Kundu M (2018) Genome-wide mRNA-miRNA profiling uncovers a role of the microRNA miR-29b-1-5p\/PHLPP1 signalling pathway in Helicobacter pylori-driven matrix metalloproteinase production in gastric epithelial cells. Cell Microbiol 20:e12859. https:\/\/doi.org\/10.1111\/cmi.12859","journal-title":"Cell Microbiol"},{"key":"11_CR42","doi-asserted-by":"publisher","unstructured":"dela Pena-Ponce MG, Jimenez MT, Hansen LM, Solnick JV, Miller LA (2017) The Helicobacter pylori type IV secretion system promotes IL-8 synthesis in a model of pediatric airway epithelium via p 38 MAP kinase. PLOS ONE 12:e0183324. https:\/\/doi.org\/10.1371\/journal.pone.0183324","DOI":"10.1371\/journal.pone.0183324"},{"key":"11_CR43","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1146\/annurev.immunol.021908.132612","volume":"27","author":"CA Dinarello","year":"2009","unstructured":"Dinarello CA (2009) Immunological and inflammatory functions of the Interleukin-1 family. Annu Rev Immunol 27:519\u2013550. https:\/\/doi.org\/10.1146\/annurev.immunol.021908.132612","journal-title":"Annu Rev Immunol"},{"key":"11_CR44","doi-asserted-by":"publisher","first-page":"e69384","DOI":"10.1371\/journal.pone.0069384","volume":"8","author":"H Ding","year":"2013","unstructured":"Ding H, Nedrud JG, Blanchard TG, Zagorski BM, Li G, Shiu J, Xu J, Czinn SJ (2013) Th1-mediated immunity against Helicobacter pylori can compensate for lack of Th17 cells and can protect mice in the absence of immunization. PLoS ONE 8:e69384. https:\/\/doi.org\/10.1371\/journal.pone.0069384","journal-title":"PLoS ONE"},{"issue":"4","key":"11_CR45","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1128\/CMR.10.4.720","volume":"10","author":"BE Dunn","year":"1997","unstructured":"Dunn BE, Cohen H, Blaser MJ (1997) Helicobacter pylori. Clin Microbiol Rev 10(4):720\u2013741","journal-title":"Clin Microbiol Rev"},{"key":"11_CR46","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1128\/iai.69.2.1025-1031.2001","volume":"69","author":"KA Eaton","year":"2001","unstructured":"Eaton KA, Mefford ME (2001) Cure of Helicobacter pylori infection and resolution of gastritis by adoptive transfer of splenocytes in mice. Infect Immun 69:1025\u20131031. https:\/\/doi.org\/10.1128\/iai.69.2.1025-1031.2001","journal-title":"Infect Immun"},{"key":"11_CR47","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1046\/j.1365-2249.2000.01374.x","volume":"122","author":"M Eck","year":"2000","unstructured":"Eck M, Schmausser B, Scheller K, Toksoy A, Kraus M, Menzel T, M\u00fcller-Hermelink HK, Gillitzer R (2000) CXC chemokines Gro(alpha)\/IL-8 and IP-10\/MIG in Helicobacter pylori gastritis. Clin Exp Immunol 122:192\u2013199","journal-title":"Clin Exp Immunol"},{"key":"11_CR48","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1038\/35006081","volume":"404","author":"EM El-Omar","year":"2000","unstructured":"El-Omar EM, Carrington M, Chow WH, McColl KE, Bream JH, Young HA, Herrera J, Lissowska J, Yuan CC, Rothman N, Lanyon G, Martin M, Fraumeni JF, Rabkin CS (2000) Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 404:398\u2013402. https:\/\/doi.org\/10.1038\/35006081","journal-title":"Nature"},{"key":"11_CR49","doi-asserted-by":"publisher","first-page":"1193","DOI":"10.1016\/S0016-5085(03)00157-4","volume":"124","author":"EM El-Omar","year":"2003","unstructured":"El-Omar EM, Rabkin CS, Gammon MD, Vaughan TL, Risch HA, Schoenberg JB, Stanford JL, Mayne ST, Goedert J, Blot WJ, Fraumeni JF, Chow W-H (2003) Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms. Gastroenterology 124:1193\u20131201","journal-title":"Gastroenterology"},{"key":"11_CR50","doi-asserted-by":"publisher","first-page":"11810","DOI":"10.1073\/pnas.1410579111","volume":"111","author":"DB Engler","year":"2014","unstructured":"Engler DB, Reuter S, van Wijck Y, Urban S, Kyburz A, Maxeiner J, Martin H, Yogev N, Waisman A, Gerhard M, Cover TL, Taube C, M\u00fcller A (2014) Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10. Proc Natl Acad Sci USA 111:11810\u201311815. https:\/\/doi.org\/10.1073\/pnas.1410579111","journal-title":"Proc Natl Acad Sci USA"},{"key":"11_CR51","doi-asserted-by":"publisher","first-page":"4915","DOI":"10.18632\/oncotarget.6642","volume":"7","author":"M Fassan","year":"2016","unstructured":"Fassan M, Saraggi D, Balsamo L, Cascione L, Castoro C, Coati I, De Bernard M, Farinati F, Guzzardo V, Valeri N, Zambon CF, Rugge M (2016) Let-7c down-regulation in Helicobacter pylori-related gastric carcinogenesis. Oncotarget 7:4915\u20134924. https:\/\/doi.org\/10.18632\/oncotarget.6642","journal-title":"Oncotarget"},{"key":"11_CR52","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1093\/infdis\/jiv467","volume":"213","author":"RM Ferreira","year":"2016","unstructured":"Ferreira RM, Pinto-Ribeiro I, Wen X, Marcos-Pinto R, Dinis-Ribeiro M, Carneiro F, Figueiredo C (2016) Helicobacter pylori cagA promoter region sequences influence CagA expression and Interleukin 8 secretion. J Infect Dis 213:669\u2013673. https:\/\/doi.org\/10.1093\/infdis\/jiv467","journal-title":"J Infect Dis"},{"key":"11_CR53","doi-asserted-by":"publisher","unstructured":"Ferwerda G, Kramer M, de\u2004Jong D, Piccini A, Joosten LA, DevesaGiner I, Girardin SE, Adema GJ, van der Meer JWM, Kullberg B-J, Rubartelli A, Netea MG (2008) Engagement of NOD2 has a dual effect on proIL-1\u03b2 mRNA transcription and secretion of bioactive IL-1\u03b2. Eur J Immunol 38:184\u2013191. https:\/\/doi.org\/10.1002\/eji.200737103","DOI":"10.1002\/eji.200737103"},{"key":"11_CR54","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1038\/ni.2231","volume":"13","author":"L Franchi","year":"2012","unstructured":"Franchi L, Mu\u00f1oz-Planillo R, N\u00fa\u00f1ez G (2012) Sensing and reacting to microbes through the inflammasomes. Nat Immunol 13:325\u2013332. https:\/\/doi.org\/10.1038\/ni.2231","journal-title":"Nat Immunol"},{"key":"11_CR55","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1128\/IAI.71.2.910-921.2003","volume":"71","author":"CA Garhart","year":"2003","unstructured":"Garhart CA, Heinzel FP, Czinn SJ, Nedrud JG (2003) Vaccine-induced reduction of Helicobacter pylori colonization in mice is interleukin-12 dependent but gamma interferon and inducible nitric oxide synthase independent. Infect Immun 71:910\u2013921","journal-title":"Infect Immun"},{"key":"11_CR56","doi-asserted-by":"publisher","first-page":"2441","DOI":"10.3892\/or.2016.4572","volume":"35","author":"Y Geng","year":"2016","unstructured":"Geng Y, Lu X, Wu X, Xue L, Wang X, Xu J (2016) MicroRNA-27b suppresses Helicobacter pylori-induced gastric tumorigenesis through negatively regulating Frizzled7. Oncol Rep 35:2441\u20132450. https:\/\/doi.org\/10.3892\/or.2016.4572","journal-title":"Oncol Rep"},{"key":"11_CR57","doi-asserted-by":"publisher","first-page":"1914","DOI":"10.1086\/386289","volume":"189","author":"AT Gewirtz","year":"2004","unstructured":"Gewirtz AT, Yu Y, Krishna US, Israel DA, Lyons SL, Peek RM (2004) Helicobacter pylori flagellin evades toll-like receptor 5-mediated innate immunity. J Infect Dis 189:1914\u20131920. https:\/\/doi.org\/10.1086\/386289","journal-title":"J Infect Dis"},{"key":"11_CR58","first-page":"883","volume":"89","author":"P Gionchetti","year":"1994","unstructured":"Gionchetti P, Vaira D, Campieri M, Holton J, Menegatti M, Belluzzi A, Bertinelli E, Ferretti M, Brignola C, Miglioli M (1994) Enhanced mucosal interleukin-6 and -8 in Helicobacter pylori-positive dyspeptic patients. Am J Gastroenterol 89:883\u2013887","journal-title":"Am J Gastroenterol"},{"key":"11_CR59","doi-asserted-by":"publisher","first-page":"8869","DOI":"10.1074\/jbc.c200651200","volume":"278","author":"SE Girardin","year":"2003","unstructured":"Girardin SE, Boneca IG, Viala J, Chamaillard M, Labigne A, Thomas G, Philpott DJ, Sansonetti PJ (2003) Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem 278:8869\u20138872. https:\/\/doi.org\/10.1074\/jbc.c200651200","journal-title":"J Biol Chem"},{"key":"11_CR60","doi-asserted-by":"publisher","unstructured":"Giza DE, Vasilescu C, Calin GA (2014) Key principles of miRNA involvement in human diseases. Discoveries (Craiova) 2:e34. https:\/\/doi.org\/10.15190\/d.2014.26","DOI":"10.15190\/d.2014.26"},{"key":"11_CR61","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1074\/jbc.m307858200","volume":"279","author":"AP Gobert","year":"2004","unstructured":"Gobert AP, Bambou J-C, Werts C, Balloy V, Chignard M, Moran AP, Ferrero RL (2004) Helicobacter pylori heat shock protein 60 mediates Interleukin-6 production by macrophages via a Toll-like receptor (TLR)-2-, TLR-4-, and myeloid differentiation factor 88-independent mechanism. J Biol Chem 279:245\u2013250. https:\/\/doi.org\/10.1074\/jbc.m307858200","journal-title":"J Biol Chem"},{"key":"11_CR62","doi-asserted-by":"publisher","first-page":"3013","DOI":"10.4049\/jimmunol.1401075","volume":"193","author":"AP Gobert","year":"2014","unstructured":"Gobert AP, Verriere T, Asim M, Barry DP, Piazuelo MB, de Sablet T, Delgado AG, Bravo LE, Correa P, Peek RM Jr, Chaturvedi R, Wilson KT (2014) Heme oxygenase-1 dysregulates macrophage polarization and the immune response to Helicobacter pylori. J Immunol 193:3013\u20133022. https:\/\/doi.org\/10.4049\/jimmunol.1401075","journal-title":"J Immunol"},{"key":"11_CR63","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1016\/j.tim.2016.02.005","volume":"24","author":"AP Gobert","year":"2016","unstructured":"Gobert AP, Wilson KT (2016) The immune battle against Helicobacter pylori infection: no offense. Trends Microbiol 24:366\u2013376. https:\/\/doi.org\/10.1016\/j.tim.2016.02.005","journal-title":"Trends Microbiol"},{"key":"11_CR64","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1038\/ni.1778","volume":"10","author":"SI Gringhuis","year":"2009","unstructured":"Gringhuis SI, den Dunnen J, Litjens M, van der Vlist M, Geijtenbeek TBH (2009) Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori. Nat Immunol 10:1081\u20131088. https:\/\/doi.org\/10.1038\/ni.1778","journal-title":"Nat Immunol"},{"key":"11_CR65","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1016\/j.immuni.2007.03.012","volume":"26","author":"SI Gringhuis","year":"2007","unstructured":"Gringhuis SI, den Dunnen J, Litjens M, van het Hof B, van Kooyk Y, Geijtenbeek TBH (2007) C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 Kinase-dependent acetylation of transcription factor NF-\u03baB. Immunity 26:605\u2013616. https:\/\/doi.org\/10.1016\/j.immuni.2007.03.012","journal-title":"Immunity"},{"key":"11_CR66","doi-asserted-by":"publisher","unstructured":"Gringhuis SI, Kaptein TM, Wevers BA, Mesman AW, Geijtenbeek TBH (2014) Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKK\u03b5- and CYLD-dependent Bcl3 activation. Nature Communications 5. https:\/\/doi.org\/10.1038\/ncomms4898","DOI":"10.1038\/ncomms4898"},{"key":"11_CR67","doi-asserted-by":"publisher","first-page":"4163","DOI":"10.1128\/IAI.71.7.4163-4166.2003","volume":"71","author":"DG Guiney","year":"2003","unstructured":"Guiney DG, Hasegawa P, Cole SP (2003) Helicobacter pylori preferentially induces interleukin 12 (IL-12) rather than IL-6 or IL-10 in human dendritic cells. Infect Immun 71:4163\u20134166","journal-title":"Infect Immun"},{"key":"11_CR68","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1038\/nm.3893","volume":"21","author":"H Guo","year":"2015","unstructured":"Guo H, Callaway JB, Ting JP-Y (2015) Inflammasomes: mechanism of action, role in disease and therapeutics. Nat Med 21:677\u2013687. https:\/\/doi.org\/10.1038\/nm.3893","journal-title":"Nat Med"},{"key":"11_CR69","doi-asserted-by":"crossref","first-page":"4229","DOI":"10.1128\/IAI.65.10.4229-4235.1997","volume":"65","author":"HA Haeberle","year":"1997","unstructured":"Haeberle HA, Kubin M, Bamford KB, Garofalo R, Graham DY, El-Zaatari F, Karttunen R, Crowe SE, Reyes VE, Ernst PB (1997) Differential stimulation of interleukin-12 (IL-12) and IL-10 by live and killed Helicobacter pylori in vitro and association of IL-12 production with gamma interferon-producing T cells in the human gastric mucosa. Infect Immun 65:4229\u20134235","journal-title":"Infect Immun"},{"key":"11_CR70","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1038\/ni.2749","volume":"14","author":"H Hara","year":"2013","unstructured":"Hara H, Tsuchiya K, Kawamura I, Fang R, Hernandez-Cuellar E, Shen Y, Mizuguchi J, Schweighoffer E, Tybulewicz V, Mitsuyama M (2013) Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity. Nat Immunol 14:1247\u20131255. https:\/\/doi.org\/10.1038\/ni.2749","journal-title":"Nat Immunol"},{"key":"11_CR71","doi-asserted-by":"publisher","first-page":"1536","DOI":"10.1136\/gutjnl-2011-301625","volume":"62","author":"Y Hayashi","year":"2013","unstructured":"Hayashi Y, Tsujii M, Wang J, Kondo J, Akasaka T, Jin Y, Li W, Nakamura T, Nishida T, Iijima H, Tsuji S, Kawano S, Hayashi N, Takehara T (2013) CagA mediates epigenetic regulation to attenuate let-7 expression in Helicobacter pylori-related carcinogenesis. Gut 62:1536\u20131546. https:\/\/doi.org\/10.1136\/gutjnl-2011-301625","journal-title":"Gut"},{"key":"11_CR72","doi-asserted-by":"publisher","unstructured":"Hedl M, Abraham C (2013) NLRP1 and NLRP3 inflammasomes are essential for distinct outcomes of decreased cytokines but enhanced bacterial killing upon chronic Nod2 stimulation. Am J Physiol-Gastrointest Liver Physiol 304:G583\u2013G596. https:\/\/doi.org\/10.1152\/ajpgi.00297.2012","DOI":"10.1152\/ajpgi.00297.2012"},{"key":"11_CR73","doi-asserted-by":"publisher","first-page":"e1003251","DOI":"10.1371\/journal.ppat.1003251","volume":"9","author":"I Hitkova","year":"2013","unstructured":"Hitkova I, Yuan G, Anderl F, Gerhard M, Kirchner T, Reu S, R\u00f6cken C, Sch\u00e4fer C, Schmid RM, Vogelmann R, Ebert MPA, Burgermeister E (2013) Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis. PLoS Pathog 9:e1003251. https:\/\/doi.org\/10.1371\/journal.ppat.1003251","journal-title":"PLoS Pathog"},{"key":"11_CR74","doi-asserted-by":"publisher","first-page":"e60363","DOI":"10.1371\/journal.pone.0060363","volume":"8","author":"DJ Horvath","year":"2013","unstructured":"Horvath DJ, Radin JN, Cho SH, Washington MK, Algood HMS (2013) The Interleukin-17 Receptor B subunit is essential for the Th2 response to Helicobacter pylori, but not for control of bacterial burden. PLoS ONE 8:e60363. https:\/\/doi.org\/10.1371\/journal.pone.0060363","journal-title":"PLoS ONE"},{"key":"11_CR75","doi-asserted-by":"publisher","first-page":"56","DOI":"10.3389\/fimmu.2012.00056","volume":"3","author":"DJ Horvath","year":"2012","unstructured":"Horvath DJ, Washington MK, Cope VA, Algood HMS (2012) IL-23 contributes to control of chronic Helicobacter pylori infection and the development of T Helper responses in a mouse model. Front Immunol 3:56. https:\/\/doi.org\/10.3389\/fimmu.2012.00056","journal-title":"Front Immunol"},{"key":"11_CR76","doi-asserted-by":"publisher","first-page":"7803","DOI":"10.1073\/pnas.0802726105","volume":"105","author":"L-C Hsu","year":"2008","unstructured":"Hsu L-C, Ali SR, McGillivray S, Tseng P-H, Mariathasan S, Humke EW, Eckmann L, Powell JJ, Nizet V, Dixit VM, Karin M (2008) A NOD2-NALP1 complex mediates caspase-1-dependent IL-1 secretion in response to Bacillus anthracis infection and muramyl dipeptide. Proc Natl Acad Sci 105:7803\u20137808. https:\/\/doi.org\/10.1073\/pnas.0802726105","journal-title":"Proc Natl Acad Sci"},{"key":"11_CR77","doi-asserted-by":"publisher","unstructured":"Hussain K, Letley DP, Greenaway AB, Kenefeck R, Winter JA, Tomlinson W, Rhead J, Staples E, Kaneko K, Atherton JC, Robinson K (2016) Helicobacter pylori-mediated protection from allergy is associated with IL-10-secreting peripheral blood regulatory T cells. Front Immunol 7. https:\/\/doi.org\/10.3389\/fimmu.2016.00071","DOI":"10.3389\/fimmu.2016.00071"},{"key":"11_CR78","doi-asserted-by":"publisher","first-page":"1406","DOI":"10.4049\/jimmunol.173.2.1406","volume":"173","author":"S Ishihara","year":"2004","unstructured":"Ishihara S, Rumi MAK, Kadowaki Y, Ortega-Cava CF, Yuki T, Yoshino N, Miyaoka Y, Kazumori H, Ishimura N, Amano Y, Kinoshita Y (2004) Essential role of MD-2 in TLR4-dependent signaling during Helicobacter pylori-associated gastritis. J Immunol 173:1406\u20131416","journal-title":"J Immunol"},{"key":"11_CR79","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1007\/s10875-011-9626-3","volume":"32","author":"H Isomoto","year":"2012","unstructured":"Isomoto H, Matsushima K, Inoue N, Hayashi T, Nakayama T, Kunizaki M, Hidaka S, Nakayama M, Hisatsune J, Nakashima M, Nagayasu T, Nakao K, Hirayama T (2012) Interweaving microRNAs and proinflammatory cytokines in gastric mucosa with reference to H. pylori infection. J Clin Immunol 32:290\u2013299. https:\/\/doi.org\/10.1007\/s10875-011-9626-3","journal-title":"J Clin Immunol"},{"key":"11_CR80","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1046\/j.1523-5378.2003.00154.x","volume":"8","author":"T Itoh","year":"2003","unstructured":"Itoh T, Yoshida M, Chiba T, Kita T, Wakatsuki Y (2003) A coordinated cytotoxic effect of IFN-gamma and cross-reactive antibodies in the pathogenesis of Helicobacter pylori gastritis. Helicobacter 8:268\u2013278","journal-title":"Helicobacter"},{"key":"11_CR81","doi-asserted-by":"publisher","first-page":"43","DOI":"10.5009\/gnl.2010.4.1.43","volume":"4","author":"Y Jo","year":"2010","unstructured":"Jo Y, Han SU, Kim YJ, Kim JH, Kim ST, Kim S-J, Hahm K-B (2010) Suppressed gastric mucosal TGF-\u03b21 increases susceptibility to H. pylori-induced gastric inflammation and ulceration: A stupid host defense response. Gut and Liver 4:43\u201353. https:\/\/doi.org\/10.5009\/gnl.2010.4.1.43","journal-title":"Gut and Liver"},{"key":"11_CR82","doi-asserted-by":"publisher","first-page":"316","DOI":"10.4049\/jimmunol.1302476","volume":"192","author":"R Kaebisch","year":"2014","unstructured":"Kaebisch R, Mej\u00edas-Luque R, Prinz C, Gerhard M (2014) Helicobacter pylori cytotoxin-associated gene A impairs human dendritic cell maturation and function through IL-10-mediated activation of STAT3. J Immunol 192:316\u2013323. https:\/\/doi.org\/10.4049\/jimmunol.1302476","journal-title":"J Immunol"},{"key":"11_CR83","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2220\/biomedres.37.21","volume":"37","author":"S Kameoka","year":"2016","unstructured":"Kameoka S, Kameyama T, Hayashi T, Sato S, Ohnishi N, Hayashi T, Murata-Kamiya N, Higashi H, Hatakeyama M, Takaoka A (2016) Helicobacter pylori induces IL-1\u03b2 protein through the inflammasome activation in differentiated macrophagic cells. Biomed Res 37:21\u201327. https:\/\/doi.org\/10.2220\/biomedres.37.21","journal-title":"Biomed Res"},{"key":"11_CR84","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1111\/j.1523-5378.2008.00612.x","volume":"13","author":"A Kandulski","year":"2008","unstructured":"Kandulski A, Wex T, Kuester D, Peitz U, Gebert I, Roessner A, Malfertheiner P (2008) Naturally occurring regulatory T cells (CD4+, CD25 high, FOXP3+) in the antrum and cardia are associated with higher Helicobacter pylori colonization and increased gene expression of TGF-beta1. Helicobacter 13:295\u2013303. https:\/\/doi.org\/10.1111\/j.1523-5378.2008.00612.x","journal-title":"Helicobacter"},{"key":"11_CR85","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1002\/path.4866","volume":"241","author":"DW Kang","year":"2017","unstructured":"Kang DW, Yang ES, Noh YN, Hwang WC, Jo S-Y, Suh Y-A, Park WS, Choi K-Y, Min DS (2017) MicroRNA-320a and microRNA-4496 attenuate Helicobacter pylori cytotoxin-associated gene A (CagA)-induced cancer-initiating potential and chemoresistance by targeting \u03b2-catenin and ATP-binding cassette, subfamily G, member 2. J Pathol 241:614\u2013625. https:\/\/doi.org\/10.1002\/path.4866","journal-title":"J Pathol"},{"key":"11_CR86","doi-asserted-by":"publisher","first-page":"G73","DOI":"10.1152\/ajpgi.00139.2005","volume":"291","author":"JY Kao","year":"2006","unstructured":"Kao JY, Rathinavelu S, Eaton KA, Bai L, Zavros Y, Takami M, Pierzchala A, Merchant JL (2006) Helicobacter pylori-secreted factors inhibit dendritic cell IL-12 secretion: a mechanism of ineffective host defense. Am J Physiol Gastrointest Liver Physiol 291:G73\u2013G81. https:\/\/doi.org\/10.1152\/ajpgi.00139.2005","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"11_CR87","doi-asserted-by":"publisher","first-page":"1046","DOI":"10.1053\/j.gastro.2009.11.043","volume":"138","author":"JY Kao","year":"2010","unstructured":"Kao JY, Zhang M, Miller MJ, Mills JC, Wang B, Liu M, Eaton KA, Zou W, Berndt BE, Cole TS, Takeuchi T, Owyang SY, Luther J (2010) Helicobacter pylori immune escape is mediated by dendritic cell-induced Treg skewing and Th17 suppression in mice. Gastroenterology 138:1046\u20131054. https:\/\/doi.org\/10.1053\/j.gastro.2009.11.043","journal-title":"Gastroenterology"},{"key":"11_CR88","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/j.cytogfr.2011.09.003","volume":"22","author":"K Kersse","year":"2011","unstructured":"Kersse K, Bertrand MJM, Lamkanfi M, Vandenabeele P (2011) NOD-like receptors and the innate immune system: Coping with danger, damage and death. Cytokine Growth Factor Rev 22:257\u2013276. https:\/\/doi.org\/10.1016\/j.cytogfr.2011.09.003","journal-title":"Cytokine Growth Factor Rev"},{"key":"11_CR89","doi-asserted-by":"publisher","first-page":"4497","DOI":"10.1038\/ncomms5497","volume":"5","author":"K Kiga","year":"2014","unstructured":"Kiga K, Mimuro H, Suzuki M, Shinozaki-Ushiku A, Kobayashi T, Sanada T, Kim M, Ogawa M, Iwasaki YW, Kayo H, Fukuda-Yuzawa Y, Yashiro M, Fukayama M, Fukao T, Sasakawa C (2014) Epigenetic silencing of miR-210 increases the proliferation of gastric epithelium during chronic Helicobacter pylori infection. Nat Commun 5:4497. https:\/\/doi.org\/10.1038\/ncomms5497","journal-title":"Nat Commun"},{"key":"11_CR90","doi-asserted-by":"publisher","first-page":"2650","DOI":"10.1002\/eji.201243281","volume":"43","author":"D-J Kim","year":"2013","unstructured":"Kim D-J, Park J-H, Franchi L, Backert S, N\u00fa\u00f1ez G (2013) The Cag pathogenicity island and interaction between TLR2\/NOD2 and NLRP3 regulate IL-1\u03b2 production in Helicobacter pylori infected dendritic cells: Immunity to infection. Eur J Immunol 43:2650\u20132658. https:\/\/doi.org\/10.1002\/eji.201243281","journal-title":"Eur J Immunol"},{"key":"11_CR91","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1186\/1471-2180-12-175","volume":"12","author":"SH Kim","year":"2012","unstructured":"Kim SH, Sierra RA, McGee DJ, Zabaleta J (2012) Transcriptional profiling of gastric epithelial cells infected with wild type or arginase-deficient Helicobacter pylori. BMC Microbiol 12:175. https:\/\/doi.org\/10.1186\/1471-2180-12-175","journal-title":"BMC Microbiol"},{"key":"11_CR92","doi-asserted-by":"publisher","first-page":"3297","DOI":"10.1172\/jci79337","volume":"125","author":"KN Koch","year":"2015","unstructured":"Koch KN, Hartung ML, Urban S, Kyburz A, Bahlmann AS, Lind J, Backert S, Taube C, M\u00fcller A (2015) Helicobacter urease-induced activation of the TLR2\/NLRP3\/IL-18 axis protects against asthma. J Clin Invest 125:3297\u20133302. https:\/\/doi.org\/10.1172\/jci79337","journal-title":"J Clin Invest"},{"key":"11_CR93","doi-asserted-by":"publisher","first-page":"E1153","DOI":"10.1073\/pnas.1116125109","volume":"109","author":"M Koch","year":"2012","unstructured":"Koch M, Mollenkopf H-J, Klemm U, Meyer TF (2012) Induction of microRNA-155 is TLR- and type IV secretion system-dependent in macrophages and inhibits DNA-damage induced apoptosis. Proc Natl Acad Sci USA 109:E1153\u2013E1162. https:\/\/doi.org\/10.1073\/pnas.1116125109","journal-title":"Proc Natl Acad Sci USA"},{"key":"11_CR94","doi-asserted-by":"publisher","first-page":"3949","DOI":"10.1038\/onc.2011.558","volume":"31","author":"D Kong","year":"2012","unstructured":"Kong D, Piao Y-S, Yamashita S, Oshima H, Oguma K, Fushida S, Fujimura T, Minamoto T, Seno H, Yamada Y, Satou K, Ushijima T, Ishikawa T-O, Oshima M (2012) Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells. Oncogene 31:3949\u20133960. https:\/\/doi.org\/10.1038\/onc.2011.558","journal-title":"Oncogene"},{"key":"11_CR95","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1128\/CDLI.10.1.22-29.2003","volume":"10","author":"S Krauss-Etschmann","year":"2003","unstructured":"Krauss-Etschmann S, Sammler E, Koletzko S, Konstantopoulos N, Aust D, Gebert B, Luckow B, Reinhardt D, Schendel DJ (2003) Chemokine receptor 5 expression in gastric mucosa of Helicobacter pylori-infected and noninfected children. Clin Diagn Lab Immunol 10:22\u201329","journal-title":"Clin Diagn Lab Immunol"},{"key":"11_CR97","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1038\/nri2936","volume":"11","author":"M Lamkanfi","year":"2011","unstructured":"Lamkanfi M (2011) Emerging inflammasome effector mechanisms. Nat Rev Immunol 11:213\u2013220. https:\/\/doi.org\/10.1038\/nri2936","journal-title":"Nat Rev Immunol"},{"key":"11_CR98","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1038\/nri3452","volume":"13","author":"E Latz","year":"2013","unstructured":"Latz E, Xiao TS, Stutz A (2013) Activation and regulation of the inflammasomes. Nat Rev Immunol 13:397\u2013411. https:\/\/doi.org\/10.1038\/nri3452","journal-title":"Nat Rev Immunol"},{"key":"11_CR99","doi-asserted-by":"publisher","unstructured":"Lee JW, Kim N, Park JH, Kim HJ, Chang H, Kim JM, Kim J-W, Lee DH (2017) Differential microRNA expression between gastric cancer tissue and non-cancerous gastric mucosa according to Helicobacter pylori Status. J Cancer Prev 22:33\u201339. https:\/\/doi.org\/10.15430\/jcp.2017.22.1.33","DOI":"10.15430\/jcp.2017.22.1.33"},{"key":"11_CR100","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1016\/0092-8674(93)90529-Y","volume":"75","author":"RC Lee","year":"1993","unstructured":"Lee RC, Feinbaum RL, Ambros V (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75:843\u2013854","journal-title":"Cell"},{"key":"11_CR101","doi-asserted-by":"publisher","first-page":"4655","DOI":"10.1007\/s11033-011-1257-5","volume":"39","author":"N Li","year":"2012","unstructured":"Li N, Xu X, Xiao B, Zhu E-D, Li B-S, Liu Z, Tang B, Zou Q-M, Liang H-P, Mao X-H (2012) Helicobacter pylori related proinflammatory cytokines contribute to the induction of miR-146a in human gastric epithelial cells. Mol Biol Rep 39:4655\u20134661. https:\/\/doi.org\/10.1007\/s11033-011-1257-5","journal-title":"Mol Biol Rep"},{"key":"11_CR102","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1080\/00365520600554477","volume":"41","author":"Z Li","year":"2006","unstructured":"Li Z, Li J (2006) Local expressions of TGF-beta1, TGF-beta1RI, CTGF, and Smad-7 in Helicobacter pylori-associated gastritis. Scand J Gastroenterol 41:1007\u20131012. https:\/\/doi.org\/10.1080\/00365520600554477","journal-title":"Scand J Gastroenterol"},{"key":"11_CR103","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1177\/1753425909357970","volume":"17","author":"A Lindgren","year":"2011","unstructured":"Lindgren A, Pavlovic V, Flach C-F, Sj\u00f6ling A, Lundin S (2011) Interferon-gamma secretion is induced in IL-12 stimulated human NK cells by recognition of Helicobacter pylori or TLR2 ligands. Innate Immun 17:191\u2013203. https:\/\/doi.org\/10.1177\/1753425909357970","journal-title":"Innate Immun"},{"key":"11_CR104","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1007\/s00535-012-0609-9","volume":"48","author":"Z Liu","year":"2013","unstructured":"Liu Z, Wang D, Hu Y, Zhou G, Zhu C, Yu Q, Chi Y, Cao Y, Jia C, Zou Q (2013) MicroRNA-146a negatively regulates PTGS2 expression induced by Helicobacter pylori in human gastric epithelial cells. J Gastroenterol 48:86\u201392. https:\/\/doi.org\/10.1007\/s00535-012-0609-9","journal-title":"J Gastroenterol"},{"key":"11_CR105","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1016\/j.micinf.2010.06.002","volume":"12","author":"Z Liu","year":"2010","unstructured":"Liu Z, Xiao B, Tang B, Li B, Li N, Zhu E, Guo G, Gu J, Zhuang Y, Liu X, Ding H, Zhao X, Guo H, Mao X, Zou Q (2010) Up-regulated microRNA-146a negatively modulate Helicobacter pylori-induced inflammatory response in human gastric epithelial cells. Microbes Infect 12:854\u2013863. https:\/\/doi.org\/10.1016\/j.micinf.2010.06.002","journal-title":"Microbes Infect"},{"key":"11_CR106","doi-asserted-by":"publisher","first-page":"4954","DOI":"10.1091\/mbc.e05-05-0426","volume":"16","author":"H Lu","year":"2005","unstructured":"Lu H, Wu JY, Kudo T, Ohno T, Graham DY, Yamaoka Y (2005) Regulation of interleukin-6 promoter activation in gastric epithelial cells infected with Helicobacter pylori. Mol Biol Cell 16:4954\u20134966. https:\/\/doi.org\/10.1091\/mbc.e05-05-0426","journal-title":"Mol Biol Cell"},{"key":"11_CR107","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1016\/j.cell.2010.08.012","volume":"142","author":"L-F Lu","year":"2010","unstructured":"Lu L-F, Boldin MP, Chaudhry A, Lin L-L, Taganov KD, Hanada T, Yoshimura A, Baltimore D, Rudensky AY (2010) Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses. Cell 142:914\u2013929. https:\/\/doi.org\/10.1016\/j.cell.2010.08.012","journal-title":"Cell"},{"key":"11_CR108","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.1128\/iai.69.3.1714-1721.2001","volume":"69","author":"B Lucas","year":"2001","unstructured":"Lucas B, Bumann D, Walduck A, Koesling J, Develioglu L, Meyer TF, Aebischer T (2001) Adoptive transfer of CD4+ T cells specific for subunit A of Helicobacter pylori urease reduces H. pylori stomach colonization in mice in the absence of interleukin-4 (IL-4)\/IL-13 receptor signaling. Infect Immun 69:1714\u20131721. https:\/\/doi.org\/10.1128\/iai.69.3.1714-1721.2001","journal-title":"Infect Immun"},{"key":"11_CR109","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1080\/09168451.2014.895661","volume":"78","author":"L Ma","year":"2014","unstructured":"Ma L, Chen Y, Zhang B, Liu G (2014) Increased microRNA-223 in Helicobacter pylori-associated gastric cancer contributed to cancer cell proliferation and migration. Biosci Biotechnol Biochem 78:602\u2013608. https:\/\/doi.org\/10.1080\/09168451.2014.895661","journal-title":"Biosci Biotechnol Biochem"},{"key":"11_CR110","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1126\/science.1103685","volume":"307","author":"S Maeda","year":"2005","unstructured":"Maeda S (2005) Nod2 mutation in Crohn\u2019s disease potentiates NF- B activity and IL-1 processing. Science 307:734\u2013738. https:\/\/doi.org\/10.1126\/science.1103685","journal-title":"Science"},{"key":"11_CR111","doi-asserted-by":"publisher","first-page":"44856","DOI":"10.1074\/jbc.m105381200","volume":"276","author":"S Maeda","year":"2001","unstructured":"Maeda S, Akanuma M, Mitsuno Y, Hirata Y, Ogura K, Yoshida H, Shiratori Y, Omata M (2001) Distinct mechanism of Helicobacter pylori mediated NF-kappa B activation between gastric cancer cells and monocytic cells. J Biol Chem 276:44856\u201344864. https:\/\/doi.org\/10.1074\/jbc.m105381200","journal-title":"J Biol Chem"},{"key":"11_CR112","doi-asserted-by":"publisher","first-page":"1967","DOI":"10.1084\/jem.20071632","volume":"205","author":"J Maelfait","year":"2008","unstructured":"Maelfait J, Vercammen E, Janssens S, Schotte P, Haegman M, Magez S, Beyaert R (2008) Stimulation of Toll-like receptor 3 and 4 induces interleukin-1\u03b2 maturation by caspase-8. J Exp Med 205:1967\u20131973. https:\/\/doi.org\/10.1084\/jem.20071632","journal-title":"J Exp Med"},{"key":"11_CR113","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1038\/s41575-018-0054-1","volume":"15","author":"SM Man","year":"2018","unstructured":"Man SM (2018) Inflammasomes in the gastrointestinal tract: infection, cancer and gut microbiota homeostasis. Nat Rev Gastroenterol Hepatol 15:721\u2013737. https:\/\/doi.org\/10.1038\/s41575-018-0054-1","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"11_CR114","doi-asserted-by":"publisher","unstructured":"Mandell L, Moran AP, Cocchiarella A, Houghton J, Taylor N, Fox JG, Wang TC, Kurt-Jones EA (2004) Intact gram-negative Helicobacter pylori, Helicobacter felis, and Helicobacter hepaticus bacteria activate innate immunity via toll-like receptor 2 but not toll-like receptor 4. Infect Immun 72:6446\u20136454. https:\/\/doi.org\/10.1128\/iai.72.11.6446-6454.2004","DOI":"10.1128\/iai.72.11.6446-6454.2004"},{"key":"11_CR115","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1038\/nri1997","volume":"7","author":"S Mariathasan","year":"2007","unstructured":"Mariathasan S, Monack DM (2007) Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation. Nat Rev Immunol 7:31\u201340. https:\/\/doi.org\/10.1038\/nri1997","journal-title":"Nat Rev Immunol"},{"key":"11_CR116","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1038\/nature04515","volume":"440","author":"S Mariathasan","year":"2006","unstructured":"Mariathasan S, Weiss DS, Newton K, McBride J, O\u2019Rourke K, Roose-Girma M, Lee WP, Weinrauch Y, Monack DM, Dixit VM (2006) Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440:228\u2013232. https:\/\/doi.org\/10.1038\/nature04515","journal-title":"Nature"},{"key":"11_CR117","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.dld.2007.11.021","volume":"40","author":"B Marotti","year":"2008","unstructured":"Marotti B, Rocco A, De Colibus P, Compare D, de Nucci G, Staibano S, Tatangelo F, Romano M, Nardone G (2008) Interleukin-13 mucosal production in Helicobacter pylori-related gastric diseases. Dig Liver Dis 40:240\u2013247. https:\/\/doi.org\/10.1016\/j.dld.2007.11.021","journal-title":"Dig Liver Dis"},{"key":"11_CR118","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/S1097-2765(02)00599-3","volume":"10","author":"F Martinon","year":"2002","unstructured":"Martinon F, Burns K, Tschopp J (2002) The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 10:417\u2013426","journal-title":"Mol Cell"},{"key":"11_CR119","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1111\/j.1523-5378.2005.00349.x","volume":"10","author":"Y Matsumoto","year":"2005","unstructured":"Matsumoto Y, Blanchard TG, Drakes ML, Basu M, Redline RW, Levine AD, Czinn SJ (2005) Eradication of Helicobacter pylori and resolution of gastritis in the gastric mucosa of IL-10-deficient mice. Helicobacter 10:407\u2013415. https:\/\/doi.org\/10.1111\/j.1523-5378.2005.00349.x","journal-title":"Helicobacter"},{"key":"11_CR120","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1002\/ijc.25348","volume":"128","author":"K Matsushima","year":"2011","unstructured":"Matsushima K, Isomoto H, Inoue N, Nakayama T, Hayashi T, Nakayama M, Nakao K, Hirayama T, Kohno S (2011) microRNA signatures in Helicobacter pylori-infected gastric mucosa. Int J Cancer 128:361\u2013370. https:\/\/doi.org\/10.1002\/ijc.25348","journal-title":"Int J Cancer"},{"key":"11_CR121","doi-asserted-by":"publisher","first-page":"e42170","DOI":"10.1371\/journal.pone.0042170","volume":"7","author":"BC Mercier","year":"2012","unstructured":"Mercier BC, Ventre E, Fogeron M-L, Debaud A-L, Tomkowiak M, Marvel J, Bonnefoy N (2012) NOD1 cooperates with TLR2 to enhance T cell receptor-mediated activation in CD8 T cells. PLoS ONE 7:e42170. https:\/\/doi.org\/10.1371\/journal.pone.0042170","journal-title":"PLoS ONE"},{"key":"11_CR122","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1111\/j.1600-065x.2011.01044.x","volume":"243","author":"EA Miao","year":"2011","unstructured":"Miao EA, Rajan JV, Aderem A (2011) Caspase-1-induced pyroptotic cell death: Caspase-1-induced pyroptotic cell death. Immunol Rev 243:206\u2013214. https:\/\/doi.org\/10.1111\/j.1600-065x.2011.01044.x","journal-title":"Immunol Rev"},{"key":"11_CR123","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1007\/s00262-014-1550-y","volume":"63","author":"L Miao","year":"2014","unstructured":"Miao L, Liu K, Xie M, Xing Y, Xi T (2014) miR-375 inhibits Helicobacter pylori-induced gastric carcinogenesis by blocking JAK2-STAT3 signaling. Cancer Immunol Immunother 63:699\u2013711. https:\/\/doi.org\/10.1007\/s00262-014-1550-y","journal-title":"Cancer Immunol Immunother"},{"key":"11_CR124","doi-asserted-by":"publisher","first-page":"1535","DOI":"10.1586\/17474124.2015.1095089","volume":"9","author":"M Miftahussurur","year":"2015","unstructured":"Miftahussurur M, Yamaoka Y (2015) Helicobacter pylori virulence genes and host genetic polymorphisms as risk factors for peptic ulcer disease. Expert Rev Gastroenterol Hepatol 9:1535\u20131547. https:\/\/doi.org\/10.1586\/17474124.2015.1095089","journal-title":"Expert Rev Gastroenterol Hepatol"},{"key":"11_CR125","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1128\/cmr.00046-08","volume":"22","author":"TH Mogensen","year":"2009","unstructured":"Mogensen TH (2009) Pathogen recognition and inflammatory signaling in innate immune defenses. Clin Microbiol Rev 22:240\u2013273. https:\/\/doi.org\/10.1128\/cmr.00046-08","journal-title":"Clin Microbiol Rev"},{"key":"11_CR126","doi-asserted-by":"publisher","first-page":"6453","DOI":"10.1128\/jb.179.20.6453-6463.1997","volume":"179","author":"AP Moran","year":"1997","unstructured":"Moran AP, Lindner B, Walsh EJ (1997) Structural characterization of the lipid A component of Helicobacter pylori rough- and smooth-form lipopolysaccharides. J Bacteriol 179:6453\u20136463","journal-title":"J Bacteriol"},{"key":"11_CR127","doi-asserted-by":"publisher","first-page":"1391","DOI":"10.1053\/j.gastro.2017.12.008","volume":"154","author":"P Morey","year":"2018","unstructured":"Morey P, Pfannkuch L, Pang E, Boccellato F, Sigal M, Imai-Matsushima A, Dyer V, Koch M, Mollenkopf H-J, Schlaermann P, Meyer TF (2018) Helicobacter pylori depletes cholesterol in gastric glands to prevent interferon gamma signaling and escape the inflammatory response. Gastroenterology 154:1391\u20131404.e9. https:\/\/doi.org\/10.1053\/j.gastro.2017.12.008","journal-title":"Gastroenterology"},{"key":"11_CR128","doi-asserted-by":"publisher","first-page":"5584","DOI":"10.4049\/jimmunol.1302865","volume":"193","author":"F Munari","year":"2014","unstructured":"Munari F, Fassan M, Capitani N, Codolo G, Vila-Caballer M, Pizzi M, Rugge M, Della Bella C, Troilo A, D\u2019Elios S, Baldari CT, D\u2019Elios MM, de Bernard M (2014) Cytokine BAFF released by Helicobacter pylori-infected macrophages triggers the Th17 response in human chronic gastritis. J Immunol 193:5584\u20135594. https:\/\/doi.org\/10.4049\/jimmunol.1302865","journal-title":"J Immunol"},{"key":"11_CR129","doi-asserted-by":"publisher","first-page":"2881","DOI":"10.1128\/iai.01517-13","volume":"82","author":"P Mustapha","year":"2014","unstructured":"Mustapha P, Paris I, Garcia M, Tran CT, Cremniter J, Garnier M, Faure J-P, Barthes T, Boneca IG, Morel F, Lecron J-C, Burucoa C, Bodet C (2014) Chemokines and antimicrobial peptides have a cag\u2014dependent early response to Helicobacter pylori infection in primary human gastric epithelial cells. Infect Immun 82:2881\u20132889. https:\/\/doi.org\/10.1128\/iai.01517-13","journal-title":"Infect Immun"},{"key":"11_CR130","doi-asserted-by":"publisher","first-page":"1666","DOI":"10.1093\/infdis\/jiv270","volume":"212","author":"H Nagashima","year":"2015","unstructured":"Nagashima H, Iwatani S, Cruz M, Jim\u00e9nez Abreu JA, Uchida T, Mahachai V, Vilaichone R-K, Graham DY, Yamaoka Y (2015) Toll-like receptor 10 in Helicobacter pylori infection. J Infect Dis 212:1666\u20131676. https:\/\/doi.org\/10.1093\/infdis\/jiv270","journal-title":"J Infect Dis"},{"key":"11_CR131","doi-asserted-by":"publisher","unstructured":"Naumann M, Sokolova O, Tegtmeyer N, Backert S (2017) Helicobacter pylori: a paradigm pathogen for subverting host cell signal transmission. Trends Microbiol 25(4):316\u2013328. https:\/\/doi.org\/10.1016\/j.tim.2016.12.004","DOI":"10.1016\/j.tim.2016.12.004"},{"key":"11_CR132","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1136\/gutjnl-2014-307175","volume":"65","author":"GZ Ng","year":"2016","unstructured":"Ng GZ, Menheniott TR, Every AL, Stent A, Judd LM, Chionh YT, Dhar P, Komen JC, Giraud AS, Wang TC, McGuckin MA, Sutton P (2016) The MUC1 mucin protects against Helicobacter pylori pathogenesis in mice by regulation of the NLRP3 inflammasome. Gut 65:1087\u20131099. https:\/\/doi.org\/10.1136\/gutjnl-2014-307175","journal-title":"Gut"},{"key":"11_CR133","doi-asserted-by":"publisher","first-page":"113","DOI":"10.3164\/jcbn.15-38","volume":"57","author":"TT Nguyen","year":"2015","unstructured":"Nguyen TT, Kim S-J, Park JM, Hahm KB, Lee H-J (2015) Repressed TGF-\u03b2 signaling through CagA-Smad3 interaction as pathogenic mechanisms of Helicobacter pylori-associated gastritis. J Clin Biochem Nutr 57:113\u2013120. https:\/\/doi.org\/10.3164\/jcbn.15-38","journal-title":"J Clin Biochem Nutr"},{"key":"11_CR134","doi-asserted-by":"publisher","first-page":"G786","DOI":"10.1152\/ajpgi.00279.2013","volume":"305","author":"JM Noto","year":"2013","unstructured":"Noto JM, Piazuelo MB, Chaturvedi R, Bartel CA, Thatcher EJ, Delgado A, Romero-Gallo J, Wilson KT, Correa P, Patton JG, Peek RM (2013) Strain-specific suppression of microRNA-320 by carcinogenic Helicobacter pylori promotes expression of the antiapoptotic protein Mcl-1. Am J Physiol Gastrointest Liver Physiol 305:G786\u2013G796. https:\/\/doi.org\/10.1152\/ajpgi.00279.2013","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"11_CR135","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1111\/j.1574-695x.2006.00105.x","volume":"47","author":"M Obonyo","year":"2006","unstructured":"Obonyo M, Cole SP, Datta SK, Guiney DG (2006) Evidence for interleukin-1-independent stimulation of interleukin-12 and down-regulation by interleukin-10 in Helicobacter pylori-infected murine dendritic cells deficient in the interleukin-1 receptor. FEMS Immunol Med Microbiol 47:414\u2013419. https:\/\/doi.org\/10.1111\/j.1574-695x.2006.00105.x","journal-title":"FEMS Immunol Med Microbiol"},{"key":"11_CR136","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1111\/j.1523-5378.2006.00400.x","volume":"11","author":"S Odenbreit","year":"2006","unstructured":"Odenbreit S, Linder S, Gebert-Vogl B, Rieder G, Moran AP, Haas R (2006) Interleukin-6 induction by Helicobacter pylori in human macrophages is dependent on phagocytosis. Helicobacter 11:196\u2013207","journal-title":"Helicobacter"},{"key":"11_CR137","doi-asserted-by":"publisher","first-page":"3047","DOI":"10.1073\/pnas.1211248110","volume":"110","author":"M Oertli","year":"2013","unstructured":"Oertli M, Noben M, Engler DB, Semper RP, Reuter S, Maxeiner J, Gerhard M, Taube C, M\u00fcller A (2013) Helicobacter pylori \u03b3-glutamyl transpeptidase and vacuolating cytotoxin promote gastric persistence and immune tolerance. Proc Natl Acad Sci USA 110:3047\u20133052. https:\/\/doi.org\/10.1073\/pnas.1211248110","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5","key":"11_CR138","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1002\/emmm.201202382","volume":"5","author":"A Ortega-G\u00f3mez","year":"2013","unstructured":"Ortega-G\u00f3mez A, Perretti M, Soehnlein O (2013) Resolution of inflammation: an integrated view. EMBO Mol Med 5(5):661\u2013674. https:\/\/doi.org\/10.1002\/emmm.201202382","journal-title":"EMBO Mol Med"},{"key":"11_CR139","doi-asserted-by":"publisher","first-page":"778","DOI":"10.1053\/j.gastro.2018.01.009","volume":"154","author":"K Pachathundikandi","year":"2018","unstructured":"Pachathundikandi K, Backert S (2018a) Heptose 1,7-bisphosphate directed TIFA oligomerization: a novel PAMP-recognizing signaling platform in the control of bacterial infections. Gastroenterology 154:778\u2013783. https:\/\/doi.org\/10.1053\/j.gastro.2018.01.009","journal-title":"Gastroenterology"},{"key":"11_CR140","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1093\/infdis\/jiw154","volume":"214","author":"SK Pachathundikandi","year":"2016","unstructured":"Pachathundikandi SK, Backert S (2016) Differential expression of interleukin 1\u03b2 during Helicobacter pylori infection of Toll-like Receptor 2 (TLR2)- and TLR10-expressing HEK293 cell lines. J Infect Dis 214:166\u2013167. https:\/\/doi.org\/10.1093\/infdis\/jiw154","journal-title":"J Infect Dis"},{"key":"11_CR141","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1177\/1753425917738043","volume":"24","author":"SK Pachathundikandi","year":"2018","unstructured":"Pachathundikandi SK, Backert S (2018b) Helicobacter pylori controls NLRP3 expression by regulating hsa-miR-223-3p and IL-10 in cultured and primary human immune cells. Innate Immun 24:11\u201323. https:\/\/doi.org\/10.1177\/1753425917738043","journal-title":"Innate Immun"},{"key":"11_CR96","doi-asserted-by":"publisher","first-page":"e19614","DOI":"10.1371\/journal.pone.0019614","volume":"6","author":"SK Pachathundikandi","year":"2011","unstructured":"Pachathundikandi SK, Brandt S, Madassery J, Backert S (2011) Induction of TLR-2 and TLR-5 expression by Helicobacter pylori switches cagPAI-dependent signalling leading to the secretion of IL-8 and TNF-\u03b1. PLoS ONE 6:e19614. https:\/\/doi.org\/10.1371\/journal.pone.0019614","journal-title":"PLoS ONE"},{"key":"11_CR142","doi-asserted-by":"publisher","first-page":"192420","DOI":"10.1155\/2015\/192420","volume":"2015","author":"SK Pachathundikandi","year":"2015","unstructured":"Pachathundikandi SK, Lind J, Tegtmeyer N, El-Omar EM, Backert S (2015) Interplay of the gastric pathogen Helicobacter pylori with Toll-like receptors. Biomed Res Int 2015:192420. https:\/\/doi.org\/10.1155\/2015\/192420","journal-title":"Biomed Res Int"},{"key":"11_CR143","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1007\/978-3-319-41171-2_6","volume":"397","author":"SK Pachathundikandi","year":"2016","unstructured":"Pachathundikandi SK, M\u00fcller A, Backert S (2016) Inflammasome activation by Helicobacter pylori and its implications for persistence and immunity. Curr Top Microbiol Immunol 397:117\u201331. https:\/\/doi.org\/10.1007\/978-3-319-41171-2_6","journal-title":"Curr Top Microbiol Immunol"},{"key":"11_CR144","doi-asserted-by":"publisher","first-page":"454","DOI":"10.4161\/gmic.27001","volume":"4","author":"SK Pachathundikandi","year":"2013","unstructured":"Pachathundikandi SK, Tegtmeyer N, Backert S (2013) Signal transduction of Helicobacter pylori during interaction with host cell protein receptors of epithelial and immune cells. Gut Microbes 4:454\u2013474. https:\/\/doi.org\/10.4161\/gmic.27001","journal-title":"Gut Microbes"},{"key":"11_CR145","doi-asserted-by":"publisher","first-page":"1288","DOI":"10.3389\/fimmu.2017.01288","volume":"8","author":"M Pagliari","year":"2017","unstructured":"Pagliari M, Munari F, Toffoletto M, Lonardi S, Chemello F, Codolo G, Millino C, Della Bella C, Pacchioni B, Vermi W, Fassan M, de Bernard M, Cagnin S (2017) Helicobacter pylori affects the antigen presentation activity of macrophages modulating the expression of the immune receptor CD300E through miR-4270. Front Immunol 8:1288. https:\/\/doi.org\/10.3389\/fimmu.2017.01288","journal-title":"Front Immunol"},{"key":"11_CR146","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1128\/IAI.71.2.794-800.2003","volume":"71","author":"K Panthel","year":"2003","unstructured":"Panthel K, Faller G, Haas R (2003) Colonization of C57BL\/6J and BALB\/c wild-type and knockout mice with Helicobacter pylori: effect of vaccination and implications for innate and acquired immunity. Infect Immun 71:794\u2013800","journal-title":"Infect Immun"},{"key":"11_CR147","doi-asserted-by":"publisher","first-page":"1738","DOI":"10.1128\/iai.01446-06","volume":"75","author":"A Pellican\u00f2","year":"2007","unstructured":"Pellican\u00f2 A, Sebkova L, Monteleone G, Guarnieri G, Imeneo M, Pallone F, Luzza F (2007) Interleukin-12 drives the Th1 signaling pathway in Helicobacter pylori-infected human gastric mucosa. Infect Immun 75:1738\u20131744. https:\/\/doi.org\/10.1128\/iai.01446-06","journal-title":"Infect Immun"},{"key":"11_CR148","doi-asserted-by":"publisher","first-page":"e88270","DOI":"10.1371\/journal.pone.0088270","volume":"9","author":"L-S Peng","year":"2014","unstructured":"Peng L-S, Zhuang Y, Li W-H, Zhou Y-Y, Wang T-T, Chen N, Cheng P, Li B-S, Guo H, Yang S-M, Chen W-S, Zou Q-M (2014) Elevated interleukin-32 expression is associated with Helicobacter pylori-related gastritis. PLoS ONE 9:e88270. https:\/\/doi.org\/10.1371\/journal.pone.0088270","journal-title":"PLoS ONE"},{"key":"11_CR149","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1128\/IAI.63.4.1183-1187.1995","volume":"63","author":"GI P\u00e9rez-P\u00e9rez","year":"1995","unstructured":"P\u00e9rez-P\u00e9rez GI, Shepherd VL, Morrow JD, Blaser MJ (1995) Activation of human THP-1 cells and rat bone marrow-derived macrophages by Helicobacter pylori lipopolysaccharide. Infect Immun 63:1183\u20131187","journal-title":"Infect Immun"},{"key":"11_CR150","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1111\/hel.12298","volume":"21","author":"J-Y Piao","year":"2016","unstructured":"Piao J-Y, Lee HG, Kim S-J, Kim D-H, Han H-J, Ngo H-K-C, Park S-A, Woo J-H, Lee J-S, Na H-K, Cha Y-N, Surh Y-J (2016) Helicobacter pylori activates IL-6-STAT3 signaling in human gastric cancer cells: potential roles for reactive oxygen species. Helicobacter 21:405\u2013416. https:\/\/doi.org\/10.1111\/hel.12298","journal-title":"Helicobacter"},{"key":"11_CR151","doi-asserted-by":"publisher","first-page":"e53798","DOI":"10.1371\/journal.pone.0053798","volume":"8","author":"IV Pinchuk","year":"2013","unstructured":"Pinchuk IV, Morris KT, Nofchissey RA, Earley RB, Wu J-Y, Ma TY, Beswick EJ (2013) Stromal cells induce Th17 during Helicobacter pylori infection and in the gastric tumor microenvironment. PLoS ONE 8:e53798. https:\/\/doi.org\/10.1371\/journal.pone.0053798","journal-title":"PLoS ONE"},{"key":"11_CR152","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1038\/nrc2857","volume":"10","author":"DB Polk","year":"2010","unstructured":"Polk DB, Peek RM (2010) Helicobacter pylori: gastric cancer and beyond. Nat Rev Cancer 10:403\u2013414. https:\/\/doi.org\/10.1038\/nrc2857","journal-title":"Nat Rev Cancer"},{"key":"11_CR153","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/1478-811x-11-77","volume":"11","author":"G Posselt","year":"2013","unstructured":"Posselt G, Backert S, Wessler S (2013) The functional interplay of Helicobacter pylori factors with gastric epithelial cells induces a multi-step process in pathogenesis. Cell Commun Signal 11:77. https:\/\/doi.org\/10.1186\/1478-811x-11-77","journal-title":"Cell Commun Signal"},{"key":"11_CR154","doi-asserted-by":"publisher","first-page":"e15018","DOI":"10.1371\/journal.pone.0015018","volume":"5","author":"M Quiding-J\u00e4rbrink","year":"2010","unstructured":"Quiding-J\u00e4rbrink M, Raghavan S, Sundquist M (2010) Enhanced M1 macrophage polarization in human Helicobacter pylori associated atrophic gastritis and in vaccinated mice. PLoS ONE 5:e15018. https:\/\/doi.org\/10.1371\/journal.pone.0015018","journal-title":"PLoS ONE"},{"key":"11_CR155","doi-asserted-by":"publisher","first-page":"2247","DOI":"10.1053\/j.gastro.2009.02.066","volume":"136","author":"R Rad","year":"2009","unstructured":"Rad R, Ballhorn W, Voland P, Eisen\u00e4cher K, Mages J, Rad L, Ferstl R, Lang R, Wagner H, Schmid RM, Bauer S, Prinz C, Kirschning CJ, Krug A (2009) Extracellular and intracellular pattern recognition receptors cooperate in the recognition of Helicobacter pylori. Gastroenterology 136:2247\u20132257. https:\/\/doi.org\/10.1053\/j.gastro.2009.02.066","journal-title":"Gastroenterology"},{"key":"11_CR156","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1053\/j.gastro.2007.04.071","volume":"133","author":"R Rad","year":"2007","unstructured":"Rad R, Brenner L, Krug A, Voland P, Mages J, Lang R, Schwendy S, Reindl W, Dossumbekova A, Ballhorn W, Wagner H, Schmid RM, Bauer S, Prinz C (2007) Toll-like receptor-dependent activation of antigen-presenting cells affects adaptive immunity to Helicobacter pylori. Gastroenterology 133:150\u2013163.e3. https:\/\/doi.org\/10.1053\/j.gastro.2007.04.071","journal-title":"Gastroenterology"},{"key":"11_CR157","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1128\/iai.02370-14","volume":"83","author":"GJ Rapsinski","year":"2015","unstructured":"Rapsinski GJ, Wynosky-Dolfi MA, Oppong GO, Tursi SA, Wilson RP, Brodsky IE, T\u00fckel \u00c7 (2015) Toll-like receptor 2 and NLRP3 cooperate to recognize a functional bacterial amyloid, curli. Infect Immun 83:693\u2013701. https:\/\/doi.org\/10.1128\/iai.02370-14","journal-title":"Infect Immun"},{"key":"11_CR158","doi-asserted-by":"publisher","first-page":"25179","DOI":"10.1074\/jbc.m400967200","volume":"279","author":"SH Rhee","year":"2004","unstructured":"Rhee SH, Keates AC, Moyer MP, Pothoulakis C (2004) MEK is a key modulator for TLR5-induced interleukin-8 and MIP3alpha gene expression in non-transformed human colonic epithelial cells. J Biol Chem 279:25179\u201325188. https:\/\/doi.org\/10.1074\/jbc.m400967200","journal-title":"J Biol Chem"},{"key":"11_CR159","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1159\/000368232","volume":"7","author":"D Rizzuti","year":"2015","unstructured":"Rizzuti D, Ang M, Sokollik C, Wu T, Abdullah M, Greenfield L, Fattouh R, Reardon C, Tang M, Diao J, Schindler C, Cattral M, Jones NL (2015) Helicobacter pylori inhibits dendritic cell maturation via interleukin-10-mediated activation of the signal transducer and activator of transcription 3 pathway. J Innate Immun 7:199\u2013211. https:\/\/doi.org\/10.1159\/000368232","journal-title":"J Innate Immun"},{"key":"11_CR160","doi-asserted-by":"publisher","first-page":"e19324","DOI":"10.1371\/journal.pone.0019324","volume":"6","author":"B Romi","year":"2011","unstructured":"Romi B, Soldaini E, Pancotto L, Castellino F, Del Giudice G, Schiavetti F (2011) Helicobacter pylori induces activation of human peripheral \u03b3\u03b4+ T lymphocytes. PLoS ONE 6:e19324. https:\/\/doi.org\/10.1371\/journal.pone.0019324","journal-title":"PLoS ONE"},{"key":"11_CR161","doi-asserted-by":"publisher","first-page":"1444","DOI":"10.1111\/cmi.12587","volume":"18","author":"AFT Rossi","year":"2016","unstructured":"Rossi AFT, Cadamuro ACT, Biselli-P\u00e9rico JM, Leite KRM, Severino FE, Reis PP, Cordeiro JA, Silva AE (2016) Interaction between inflammatory mediators and miRNAs in Helicobacter pylori infection. Cell Microbiol 18:1444\u20131458. https:\/\/doi.org\/10.1111\/cmi.12587","journal-title":"Cell Microbiol"},{"key":"11_CR162","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1053\/j.gastro.2010.08.044","volume":"140","author":"Y Saito","year":"2011","unstructured":"Saito Y, Suzuki H, Tsugawa H, Suzuki S, Matsuzaki J, Hirata K, Hibi T (2011) Dysfunctional gastric emptying with down-regulation of muscle-specific microRNAs in Helicobacter pylori-infected mice. Gastroenterology 140:189\u2013198. https:\/\/doi.org\/10.1053\/j.gastro.2010.08.044","journal-title":"Gastroenterology"},{"key":"11_CR163","doi-asserted-by":"publisher","first-page":"3795","DOI":"10.1128\/iai.00637-12","volume":"80","author":"K Sakitani","year":"2012","unstructured":"Sakitani K, Hirata Y, Hayakawa Y, Serizawa T, Nakata W, Takahashi R, Kinoshita H, Sakamoto K, Nakagawa H, Akanuma M, Yoshida H, Maeda S, Koike K (2012) Role of interleukin-32 in Helicobacter pylori-induced gastric inflammation. Infect Immun 80:3795\u20133803. https:\/\/doi.org\/10.1128\/iai.00637-12","journal-title":"Infect Immun"},{"key":"11_CR164","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1038\/nrmicro3016","volume":"11","author":"NR Salama","year":"2013","unstructured":"Salama NR, Hartung ML, M\u00fcller A (2013) Life in the human stomach: persistence strategies of the bacterial pathogen Helicobacter pylori. Nat Rev Microbiol 11:385\u2013399. https:\/\/doi.org\/10.1038\/nrmicro3016","journal-title":"Nat Rev Microbiol"},{"key":"11_CR165","doi-asserted-by":"publisher","first-page":"6773","DOI":"10.1128\/iai.72.12.6773-6779.2004","volume":"72","author":"B Schmausser","year":"2004","unstructured":"Schmausser B, Josenhans C, Endrich S, Suerbaum S, Sitaru C, Andrulis M, Br\u00e4ndlein S, Rieckmann P, M\u00fcller-Hermelink HK, Eck M (2004) Downregulation of CXCR1 and CXCR2 expression on human neutrophils by Helicobacter pylori: a new pathomechanism in H. pylori infection? Infect Immun 72:6773\u20136779. https:\/\/doi.org\/10.1128\/iai.72.12.6773-6779.2004","journal-title":"Infect Immun"},{"key":"11_CR166","doi-asserted-by":"publisher","first-page":"1273","DOI":"10.1096\/fj.201601222r","volume":"31","author":"CN Serhan","year":"2017","unstructured":"Serhan CN (2017) Treating inflammation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms. FASEB J 31:1273\u20131288. https:\/\/doi.org\/10.1096\/fj.201601222r","journal-title":"FASEB J"},{"key":"11_CR167","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1038\/mi.2012.133","volume":"6","author":"C Serrano","year":"2013","unstructured":"Serrano C, Wright SW, Bimczok D, Shaffer CL, Cover TL, Venegas A, Salazar MG, Smythies LE, Harris PR, Smith PD (2013) Downregulated Th17 responses are associated with reduced gastritis in Helicobacter pylori-infected children. Mucosal Immunol 6:950\u2013959. https:\/\/doi.org\/10.1038\/mi.2012.133","journal-title":"Mucosal Immunol"},{"key":"11_CR168","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1096\/fj.201701456rr","volume":"33","author":"L Shao","year":"2019","unstructured":"Shao L, Chen Z, Soutto M, Zhu S, Lu H, Romero-Gallo J, Peek R, Zhang S, El-Rifai W (2019) Helicobacter pylori-induced miR-135b-5p promotes cisplatin resistance in gastric cancer. FASEB J 33:264\u2013274. https:\/\/doi.org\/10.1096\/fj.201701456rr","journal-title":"FASEB J"},{"key":"11_CR169","doi-asserted-by":"publisher","first-page":"5121","DOI":"10.4049\/jimmunol.0901115","volume":"184","author":"Y Shi","year":"2010","unstructured":"Shi Y, Liu X-F, Zhuang Y, Zhang J-Y, Liu T, Yin Z, Wu C, Mao X-H, Jia K-R, Wang F-J, Guo H, Flavell RA, Zhao Z, Liu K-Y, Xiao B, Guo Y, Zhang W-J, Zhou W-Y, Guo G, Zou Q-M (2010) Helicobacter pylori-induced Th17 responses modulate Th1 cell responses, benefit bacterial growth, and contribute to pathology in mice. J Immunol 184:5121\u20135129. https:\/\/doi.org\/10.4049\/jimmunol.0901115","journal-title":"J Immunol"},{"key":"11_CR170","doi-asserted-by":"publisher","first-page":"136","DOI":"10.3748\/wjg.v11.i1.136","volume":"11","author":"S-C Shih","year":"2005","unstructured":"Shih S-C (2005) Expression patterns of transforming growth factor-beta and its receptors in gastric mucosa of patients with refractory gastric ulcer. World J Gastroenterol 11:136. https:\/\/doi.org\/10.3748\/wjg.v11.i1.136","journal-title":"World J Gastroenterol"},{"key":"11_CR171","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1046\/j.1523-5378.2002.00077.x","volume":"7","author":"T Shimoyama","year":"2002","unstructured":"Shimoyama T, Fukuda S, Liu Q, Nakaji S, Fukuda Y, Sugawara K (2002) Production of chemokines and reactive oxygen species by human neutrophils stimulated by Helicobacter pylori. Helicobacter 7:170\u2013174","journal-title":"Helicobacter"},{"key":"11_CR172","doi-asserted-by":"publisher","first-page":"988","DOI":"10.1007\/s00535-012-0562-7","volume":"47","author":"A Shiotani","year":"2012","unstructured":"Shiotani A, Uedo N, Iishi H, Murao T, Kanzaki T, Kimura Y, Kamada T, Kusunoki H, Inoue K, Haruma K (2012) Helicobacter pylori eradication did not improve dysregulation of specific oncogenic miRNAs in intestinal metaplastic glands. J Gastroenterol 47:988\u2013998. https:\/\/doi.org\/10.1007\/s00535-012-0562-7","journal-title":"J Gastroenterol"},{"key":"11_CR173","doi-asserted-by":"publisher","unstructured":"Sj\u00f6kvist Ottsj\u00f6 L, Flach C-F, Nilsson S, Malefyt R de W, Walduck AK, Raghavan S (2015) Defining the roles of IFN-\u03b3 and IL-17A in inflammation and protection against Helicobacter pylori infection. PLoS ONE 10:e0131444. https:\/\/doi.org\/10.1371\/journal.pone.0131444","DOI":"10.1371\/journal.pone.0131444"},{"key":"11_CR174","doi-asserted-by":"publisher","first-page":"e12514","DOI":"10.1111\/hel.12514","volume":"23","author":"O Sjomina","year":"2018","unstructured":"Sjomina O, Pavlova J, Niv Y, Leja M (2018) Epidemiology of Helicobacter pylori infection. Helicobacter 23:e12514. https:\/\/doi.org\/10.1111\/hel.12514","journal-title":"Helicobacter"},{"key":"11_CR175","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1007\/s10787-017-0360-1","volume":"25","author":"BL Slomiany","year":"2017","unstructured":"Slomiany BL, Slomiany A (2017) Role of LPS-elicited signaling in triggering gastric mucosal inflammatory responses to Helicobacter pylori: modulatory effect of ghrelin. Inflammopharmacology 25:415\u2013429. https:\/\/doi.org\/10.1007\/s10787-017-0360-1","journal-title":"Inflammopharmacology"},{"key":"11_CR176","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1038\/ni1011","volume":"4","author":"KD Smith","year":"2003","unstructured":"Smith KD, Andersen-Nissen E, Hayashi F, Strobe K, Bergman MA, Barrett SL, Cookson BT, Aderem A (2003a) Toll-like receptor 5 recognizes a conserved site on flagellin required for protofilament formation and bacterial motility. Nat Immunol 4:1247\u20131253. https:\/\/doi.org\/10.1038\/ni1011","journal-title":"Nat Immunol"},{"key":"11_CR177","doi-asserted-by":"publisher","first-page":"32552","DOI":"10.1074\/jbc.m305536200","volume":"278","author":"MF Smith","year":"2003","unstructured":"Smith MF, Mitchell A, Li G, Ding S, Fitzmaurice AM, Ryan K, Crowe S, Goldberg JB (2003b) Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-kappa B activation and chemokine expression by epithelial cells. J Biol Chem 278:32552\u201332560. https:\/\/doi.org\/10.1074\/jbc.m305536200","journal-title":"J Biol Chem"},{"key":"11_CR178","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1002\/1521-4141(200102)31:2<396::aid-immu396>3.0.co;2-y","volume":"31","author":"F Sommer","year":"2001","unstructured":"Sommer F, Faller G, R\u00f6llinghoff M, Kirchner T, Mak TW, Lohoff M (2001) Lack of gastritis and of an adaptive immune response in interferon regulatory factor-1-deficient mice infected with Helicobacter pylori. Eur J Immunol 31:396\u2013402. https:\/\/doi.org\/10.1002\/1521-4141(200102)31:2%3c396:aid-immu396%3e3.0.co;2-y","journal-title":"Eur J Immunol"},{"key":"11_CR179","doi-asserted-by":"publisher","first-page":"e61250","DOI":"10.1371\/journal.pone.0061250","volume":"8","author":"M Song","year":"2013","unstructured":"Song M, Su H, Zhang L, Ma J, Li J, Pan K, You W (2013) Genetic polymorphisms of miR-146a and miR-27a, Helicobacter pylori infection, and risk of gastric lesions in a Chinese population. PLoS ONE 8:e61250. https:\/\/doi.org\/10.1371\/journal.pone.0061250","journal-title":"PLoS ONE"},{"key":"11_CR180","doi-asserted-by":"publisher","first-page":"7012","DOI":"10.1128\/jb.00667-08","volume":"190","author":"CM Stead","year":"2008","unstructured":"Stead CM, Beasley A, Cotter RJ, Trent MS (2008) Deciphering the unusual acylation pattern of Helicobacter pylori lipid A. J Bacteriol 190:7012\u20137021. https:\/\/doi.org\/10.1128\/jb.00667-08","journal-title":"J Bacteriol"},{"key":"11_CR181","doi-asserted-by":"publisher","first-page":"3496","DOI":"10.1128\/IAI.71.6.3496-3502.2003","volume":"71","author":"B Su","year":"2003","unstructured":"Su B, Ceponis PJM, Lebel S, Huynh H, Sherman PM (2003) Helicobacter pylori activates Toll-like receptor 4 expression in gastrointestinal epithelial cells. Infect Immun 71:3496\u20133502","journal-title":"Infect Immun"},{"key":"11_CR182","doi-asserted-by":"publisher","first-page":"1677","DOI":"10.1111\/j.1440-1746.2011.06817.x","volume":"26","author":"M Sugimoto","year":"2011","unstructured":"Sugimoto M, Ohno T, Graham DY, Yamaoka Y (2011) Helicobacter pylori outer membrane proteins on gastric mucosal interleukin 6 and 11 expression in Mongolian gerbils: OMPs of H. pylori and gerbils. J Gastroenterol Hepatol 26:1677\u20131684. https:\/\/doi.org\/10.1111\/j.1440-1746.2011.06817.x","journal-title":"J Gastroenterol Hepatol"},{"key":"11_CR183","doi-asserted-by":"publisher","first-page":"160","DOI":"10.3389\/fimmu.2016.00160","volume":"7","author":"MA Sugimoto","year":"2016","unstructured":"Sugimoto MA, Sousa LP, Pinho V, Perretti M, Teixeira MM (2016) Resolution of inflammation: what controls its onset? Front Immunol 7:160. https:\/\/doi.org\/10.3389\/fimmu.2016.00160","journal-title":"Front Immunol"},{"key":"11_CR184","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1016\/j.cell.2010.01.022","volume":"140","author":"O Takeuchi","year":"2010","unstructured":"Takeuchi O, Akira S (2010) Pattern recognition receptors and inflammation. Cell 140:805\u2013820. https:\/\/doi.org\/10.1016\/j.cell.2010.01.022","journal-title":"Cell"},{"key":"11_CR185","doi-asserted-by":"publisher","unstructured":"Tang B, Li N, Gu J, Zhuang Y, Li Q, Wang HG, Fang Y, Yu B, Zhang JY, Xie QH,Chen L, Jiang XJ, Xiao B, Zou QM, Mao XH (2012) Compromised autophagy by MIR30B benefits the intracellular survival of Helicobacter pylori. Autophagy 8:1045\u20131057. https:\/\/doi.org\/10.4161\/auto.20159","DOI":"10.4161\/auto.20159"},{"key":"11_CR186","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1111\/cas.13462","volume":"109","author":"G Teng","year":"2018","unstructured":"Teng G, Dai Y, Chu Y, Li J, Zhang H, Wu T, Shuai X, Wang W (2018) Helicobacter pylori induces caudal-type homeobox protein 2 and cyclooxygenase 2 expression by modulating microRNAs in esophageal epithelial cells. Cancer Sci 109:297\u2013307. https:\/\/doi.org\/10.1111\/cas.13462","journal-title":"Cancer Sci"},{"key":"11_CR187","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.1128\/iai.73.3.1523-1531.2005","volume":"73","author":"AM Torok","year":"2005","unstructured":"Torok AM, Bouton AH, Goldberg JB (2005) Helicobacter pylori induces interleukin-8 secretion by Toll-like receptor 2- and Toll-like receptor 5-dependent and -independent pathways. Infect Immun 73:1523\u20131531. https:\/\/doi.org\/10.1128\/iai.73.3.1523-1531.2005","journal-title":"Infect Immun"},{"key":"11_CR188","doi-asserted-by":"publisher","first-page":"4531","DOI":"10.1128\/jb.00146-06","volume":"188","author":"AX Tran","year":"2006","unstructured":"Tran AX, Whittimore JD, Wyrick PB, McGrath SC, Cotter RJ, Trent MS (2006) The lipid A 1-phosphatase of Helicobacter pylori is required for resistance to the antimicrobial peptide polymyxin. J Bacteriol 188:4531\u20134541. https:\/\/doi.org\/10.1128\/jb.00146-06","journal-title":"J Bacteriol"},{"key":"11_CR189","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1038\/ni.1823","volume":"11","author":"LH Travassos","year":"2010","unstructured":"Travassos LH, Carneiro LAM, Ramjeet M, Hussey S, Kim Y-G, Magalh\u00e3es JG, Yuan L, Soares F, Chea E, Le Bourhis L, Boneca IG, Allaoui A, Jones NL, Nu\u00f1ez G, Girardin SE, Philpott DJ (2010) Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol 11:55\u201362. https:\/\/doi.org\/10.1038\/ni.1823","journal-title":"Nat Immunol"},{"key":"11_CR190","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1080\/21505594.2015.1043505","volume":"6","author":"C-C Tsai","year":"2015","unstructured":"Tsai C-C, Kuo T-Y, Hong Z-W, Yeh Y-C, Shih K-S, Du S-Y, Fu H-W (2015) Helicobacter pylori neutrophil-activating protein induces release of histamine and interleukin-6 through G protein-mediated MAPKs and PI3 K\/Akt pathways in HMC-1 cells. Virulence 6:755\u2013765. https:\/\/doi.org\/10.1080\/21505594.2015.1043505","journal-title":"Virulence"},{"key":"11_CR191","doi-asserted-by":"publisher","unstructured":"Varga MG, Shaffer CL, Sierra JC, Suarez G, Piazuelo MB, Whitaker ME, Romero-Gallo J, Krishna US, Delgado A, Gomez MA, Good JAD, Almqvist F, Skaar EP, Correa P, Wilson KT, Hadjifrangiskou M, Peek RM (2016) Pathogenic Helicobacter pylori strains translocate DNA and activate TLR9 via the cancer-associated cag type IV secretion system. Oncogene 35:6262\u20136269. https:\/\/doi.org\/10.1038\/onc.2016.158","DOI":"10.1038\/onc.2016.158"},{"key":"11_CR192","doi-asserted-by":"publisher","unstructured":"Wang F, Liu J, Zou Y, Jiao Y, Huang Y, Fan L, Li X, Yu H, He C, Wei W, Wang H, Sun G (2017) MicroRNA-143-3p, up-regulated in Helicobacter pylori-positive gastric cancer, suppresses tumor growth, migration and invasion by directly targeting AKT2. Oncotarget 8:28711\u201328724. https:\/\/doi.org\/10.18632\/oncotarget.15646","DOI":"10.18632\/oncotarget.15646"},{"key":"11_CR193","doi-asserted-by":"publisher","first-page":"4149","DOI":"10.4049\/jimmunol.1400594","volume":"193","author":"Y-C Wang","year":"2014","unstructured":"Wang Y-C, Chen C-L, Sheu B-S, Yang Y-J, Tseng P-C, Hsieh C-Y, Lin C-F (2014) Helicobacter pylori infection activates Src homology-2 domain-containing phosphatase 2 to suppress IFN-\u03b3 signaling. J Immunol 193:4149\u20134158. https:\/\/doi.org\/10.4049\/jimmunol.1400594","journal-title":"J Immunol"},{"key":"11_CR194","doi-asserted-by":"publisher","first-page":"137","DOI":"10.2147\/jir.s64888","volume":"8","author":"JR White","year":"2015","unstructured":"White JR, Winter JA, Robinson K (2015) Differential inflammatory response to Helicobacter pylori infection: etiology and clinical outcomes. J Inflamm Res 8:137\u2013147. https:\/\/doi.org\/10.2147\/jir.s64888","journal-title":"J Inflamm Res"},{"key":"11_CR195","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1016\/0092-8674(93)90530-4","volume":"75","author":"B Wightman","year":"1993","unstructured":"Wightman B, Ha I, Ruvkun G (1993) Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75:855\u2013862","journal-title":"Cell"},{"key":"11_CR196","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1053\/j.gastro.2007.05.008","volume":"133","author":"KT Wilson","year":"2007","unstructured":"Wilson KT, Crabtree JE (2007) Immunology of Helicobacter pylori: insights into the failure of the immune response and perspectives on vaccine studies. Gastroenterology 133:288\u2013308. https:\/\/doi.org\/10.1053\/j.gastro.2007.05.008","journal-title":"Gastroenterology"},{"key":"11_CR197","doi-asserted-by":"publisher","first-page":"5583","DOI":"10.7314\/APJCP.2014.15.14.5583","volume":"15","author":"K Wu","year":"2014","unstructured":"Wu K, Yang L, Li C, Zhu C-H, Wang X, Yao Y, Jia Y-J (2014) MicroRNA-146a enhances Helicobacter pylori induced cell apoptosis in human gastric cancer epithelial cells. Asian Pac J Cancer Prev 15:5583\u20135586","journal-title":"Asian Pac J Cancer Prev"},{"key":"11_CR198","first-page":"1494","volume":"58","author":"MS Wu","year":"1998","unstructured":"Wu MS, Lee CW, Shun CT, Wang HP, Lee WJ, Sheu JC, Lin JT (1998) Clinicopathological significance of altered loci of replication error and microsatellite instability-associated mutations in gastric cancer. Cancer Res 58:1494\u20131497","journal-title":"Cancer Res"},{"key":"11_CR199","doi-asserted-by":"publisher","first-page":"30","DOI":"10.4103\/1319-3767.173756","volume":"22","author":"K Wu","year":"2016","unstructured":"Wu K, Zhu C, Yao Y, Wang X, Song J, Zhai J (2016) MicroRNA-155-enhanced autophagy in human gastric epithelial cell in response to Helicobacter pylori. Saudi J Gastroenterol 22:30\u201336. https:\/\/doi.org\/10.4103\/1319-3767.173756","journal-title":"Saudi J Gastroenterol"},{"key":"11_CR200","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1086\/605443","volume":"200","author":"B Xiao","year":"2009","unstructured":"Xiao B, Liu Z, Li B-S, Tang B, Li W, Guo G, Shi Y, Wang F, Wu Y, Tong W-D, Guo H, Mao X-H, Zou Q-M (2009) Induction of microRNA-155 during Helicobacter pylori infection and its negative regulatory role in the inflammatory response. J Infect Dis 200:916\u2013925. https:\/\/doi.org\/10.1086\/605443","journal-title":"J Infect Dis"},{"key":"11_CR201","doi-asserted-by":"publisher","first-page":"e0168822","DOI":"10.1371\/journal.pone.0168822","volume":"12","author":"G Xie","year":"2017","unstructured":"Xie G, Li W, Li R, Wu K, Zhao E, Zhang Y, Zhang P, Shi L, Wang D, Yin Y, Deng R, Tao K (2017) Helicobacter pylori promote B7-H1 expression by suppressing miR-152 and miR-200b in gastric cancer cells. PLoS ONE 12:e0168822. https:\/\/doi.org\/10.1371\/journal.pone.0168822","journal-title":"PLoS ONE"},{"key":"11_CR202","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1136\/gut.42.5.609","volume":"42","author":"Y Yamaoka","year":"1998","unstructured":"Yamaoka Y, Kita M, Kodama T, Sawai N, Tanahashi T, Kashima K, Imanishi J (1998) Chemokines in the gastric mucosa in Helicobacter pylori infection. Gut 42:609\u2013617","journal-title":"Gut"},{"key":"11_CR203","doi-asserted-by":"publisher","first-page":"3978","DOI":"10.3748\/wjg.v22.i15.3978","volume":"22","author":"X-J Yang","year":"2016","unstructured":"Yang X-J, Si R-H, Liang Y-H, Ma B-Q, Jiang Z-B, Wang B, Gao P (2016) Mir-30d increases intracellular survival of Helicobacter pylori through inhibition of autophagy pathway. World J Gastroenterol 22:3978\u20133991. https:\/\/doi.org\/10.3748\/wjg.v22.i15.3978","journal-title":"World J Gastroenterol"},{"key":"11_CR204","doi-asserted-by":"publisher","first-page":"2120","DOI":"10.1002\/ijc.29268","volume":"136","author":"F Ye","year":"2015","unstructured":"Ye F, Tang C, Shi W, Qian J, Xiao S, Gu M, Dang Y, Liu J, Chen Y, Shi R, Zhang G (2015) A MDM2-dependent positive-feedback loop is involved in inhibition of miR-375 and miR-106b induced by Helicobacter pylori lipopolysaccharide. Int J Cancer 136:2120\u20132131. https:\/\/doi.org\/10.1002\/ijc.29268","journal-title":"Int J Cancer"},{"key":"11_CR205","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1111\/j.1574-695x.2007.00288.x","volume":"51","author":"S Yokota","year":"2007","unstructured":"Yokota S, Ohnishi T, Muroi M, Tanamoto K, Fujii N, Amano K (2007) Highly-purified Helicobacter pylori LPS preparations induce weak inflammatory reactions and utilize Toll-like receptor 2 complex but not Toll-like receptor 4 complex. FEMS Immunol Med Microbiol 51:140\u2013148. https:\/\/doi.org\/10.1111\/j.1574-695x.2007.00288.x","journal-title":"FEMS Immunol Med Microbiol"},{"key":"11_CR206","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.1128\/iai.73.3.1482-1490.2005","volume":"73","author":"CH Yun","year":"2005","unstructured":"Yun CH, Lundgren A, Azem J, Sj\u00f6ling A, Holmgren J, Svennerholm A-M, Lundin BS (2005) Natural killer cells and Helicobacter pylori infection: bacterial antigens and interleukin-12 act synergistically to induce gamma interferon production. Infect Immun 73:1482\u20131490. https:\/\/doi.org\/10.1128\/iai.73.3.1482-1490.2005","journal-title":"Infect Immun"},{"key":"11_CR207","doi-asserted-by":"publisher","first-page":"1004621","DOI":"10.1371\/journal.ppat.1004621","volume":"11","author":"XS Zhang","year":"2015","unstructured":"Zhang XS, Tegtmeyer N, Traube L, Jindal S, Perez-Perez G, Sticht H, Backert S, Blaser MJ (2015) A specific A\/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interaction. PloS Pathog 11:1004621. https:\/\/doi.org\/10.1371\/journal.ppat.1004621","journal-title":"PloS Pathog"},{"key":"11_CR208","doi-asserted-by":"publisher","unstructured":"Zhang YM, Noto JM, Hammond CE, Barth JL, Argraves WS, Backert S, Peek RM Jr,Smolka AJ (2014) Helicobacter pylori-induced posttranscriptional regulation of H-K-ATPase \u03b1-subunit gene expression by miRNA. Am J Physiol Gastrointest Liver Physiol 306:G606-613. https:\/\/doi.org\/10.1152\/ajpgi.00333.2013","DOI":"10.1152\/ajpgi.00333.2013"},{"key":"11_CR209","doi-asserted-by":"publisher","first-page":"1358","DOI":"10.1038\/labinvest.2008.94","volume":"88","author":"Z Zhang","year":"2008","unstructured":"Zhang Z, Li Z, Gao C, Chen P, Chen J, Liu W, Xiao S, Lu H (2008) miR-21 plays a pivotal role in gastric cancer pathogenesis and progression. Lab Invest 88:1358\u20131366. https:\/\/doi.org\/10.1038\/labinvest.2008.94","journal-title":"Lab Invest"},{"key":"11_CR210","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1099\/jmm.0.46882-0","volume":"56","author":"Y Zhao","year":"2007","unstructured":"Zhao Y, Yokota K, Ayada K, Yamamoto Y, Okada T, Shen L, Oguma K (2007) Helicobacter pylori heat-shock protein 60 induces interleukin-8 via a Toll-like receptor (TLR)2 and mitogen-activated protein (MAP) kinase pathway in human monocytes. J Med Microbiol 56:154\u2013164. https:\/\/doi.org\/10.1099\/jmm.0.46882-0","journal-title":"J Med Microbiol"},{"key":"11_CR211","doi-asserted-by":"publisher","first-page":"e101457","DOI":"10.1371\/journal.pone.0101457","volume":"9","author":"X Zhou","year":"2014","unstructured":"Zhou X, Li L, Su J, Zhang G (2014a) Decreased miR-204 in Helicobacter pylori-associated gastric cancer promotes cancer cell proliferation and invasion by targeting SOX4. PLoS ONE 9:e101457. https:\/\/doi.org\/10.1371\/journal.pone.0101457","journal-title":"PLoS ONE"},{"key":"11_CR212","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1038\/s41392-018-0006-9","volume":"3","author":"X Zhou","year":"2018","unstructured":"Zhou X, Li X, Wu M (2018) miRNAs reshape immunity and inflammatory responses in bacterial infection. Signal Transduct Target Ther 3:14. https:\/\/doi.org\/10.1038\/s41392-018-0006-9","journal-title":"Signal Transduct Target Ther"},{"key":"11_CR213","doi-asserted-by":"publisher","unstructured":"Zhou X, Xu G, Yin C, Jin W, Zhang G (2014b) Down-regulation of miR-203 induced by Helicobacter pylori infection promotes the proliferation and invasion of gastric cancer by targeting CASK. Oncotarget 5:11631\u201311640. https:\/\/doi.org\/10.18632\/oncotarget.2600","DOI":"10.18632\/oncotarget.2600"},{"key":"11_CR214","doi-asserted-by":"publisher","first-page":"e35147","DOI":"10.1371\/journal.pone.0035147","volume":"7","author":"Y Zhu","year":"2012","unstructured":"Zhu Y, Jiang Q, Lou X, Ji X, Wen Z, Wu J, Tao H, Jiang T, He W, Wang C, Du Q, Zheng S, Mao J, Huang J (2012) microRNAs up-regulated by CagA of Helicobacter pylori induce intestinal metaplasia of gastric epithelial cells. PLoS ONE 7:e35147. https:\/\/doi.org\/10.1371\/journal.pone.0035147","journal-title":"PLoS ONE"},{"key":"11_CR215","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.1136\/gutjnl-2014-307020","volume":"64","author":"Y Zhuang","year":"2015","unstructured":"Zhuang Y, Cheng P, Liu X, Peng L, Li B, Wang T, Chen N, Li W, Shi Y, Chen W, Pang KC, Zeng M, Mao X, Yang S, Guo H, Guo G, Liu T, Zuo Q, Yang H, Yang L, Mao F, Lv Y, Zou Q (2015) A pro-inflammatory role for Th22 cells in Helicobacter pylori-associated gastritis. Gut 64:1368\u20131378. https:\/\/doi.org\/10.1136\/gutjnl-2014-307020","journal-title":"Gut"}],"container-title":["Current Topics in Microbiology and Immunology","Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter pylori"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-030-15138-6_11","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,14]],"date-time":"2020-12-14T22:49:59Z","timestamp":1607986199000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-030-15138-6_11"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"ISBN":["9783030151379","9783030151386"],"references-count":215,"URL":"https:\/\/doi.org\/10.1007\/978-3-030-15138-6_11","relation":{},"ISSN":["0070-217X","2196-9965"],"issn-type":[{"value":"0070-217X","type":"print"},{"value":"2196-9965","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]},"assertion":[{"value":"24 May 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}