{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T13:43:37Z","timestamp":1783691017708,"version":"3.55.0"},"publisher-location":"Cham","reference-count":172,"publisher":"Springer International Publishing","isbn-type":[{"value":"9783030151379","type":"print"},{"value":"9783030151386","type":"electronic"}],"license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019]]},"DOI":"10.1007\/978-3-030-15138-6_4","type":"book-chapter","created":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T14:10:00Z","timestamp":1558620600000},"page":"77-106","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["MALT Lymphoma as a Model of Chronic Inflammation-Induced Gastric Tumor Development"],"prefix":"10.1007","author":[{"given":"Lukas","family":"Marcelis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Tousseyn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Sagaert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,5,24]]},"reference":[{"key":"4_CR1","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1002\/1098-2264(2000)9999:9999<::AID-GCC1048>3.0.CO;2-B","volume":"29","author":"R Achuthan","year":"2000","unstructured":"Achuthan R, Bell SM, Leek JP et al (2000) Novel translocation of the BCL10 gene in a case of mucosa associated lymphoid tissue lymphoma. Genes Chromosomes Cancer 29:347\u2013349. https:\/\/doi.org\/10.1002\/1098-2264(2000)9999:9999%3c:AID-GCC1048%3e3.0.CO;2-B","journal-title":"Genes Chromosomes Cancer"},{"key":"4_CR2","doi-asserted-by":"publisher","first-page":"3286","DOI":"10.1111\/febs.13325","volume":"282","author":"IS Afonina","year":"2015","unstructured":"Afonina IS, Elton L, Carpentier I, Beyaert R (2015) MALT1\u2014a universal soldier: multiple strategies to ensure NF-\u03baB activation and target gene expression. FEBS J 282:3286\u20133297. https:\/\/doi.org\/10.1111\/febs.13325","journal-title":"FEBS J"},{"key":"4_CR3","doi-asserted-by":"publisher","first-page":"4014","DOI":"10.1182\/blood.V98.1.250","volume":"95","author":"B Alpen","year":"2000","unstructured":"Alpen B, Neubauer A, Dierlamm J et al (2000) Translocation t(11;18) absent in early gastric marginal zone B-cell lymphoma of MALT type responding to eradication of Helicobacter pylori infection. Blood 95:4014\u20134015. https:\/\/doi.org\/10.1182\/blood.V98.1.250","journal-title":"Blood"},{"key":"4_CR4","doi-asserted-by":"publisher","first-page":"3949","DOI":"10.1182\/blood-2011-11-389908","volume":"120","author":"SM Ansell","year":"2012","unstructured":"Ansell SM, Akasaka T, McPhail E et al (2012) t(X;14)(p 11;q32) in MALT lymphoma involving GPR34 reveals a role for GPR34 in tumor cell growth. Blood 120:3949\u20133957. https:\/\/doi.org\/10.1182\/blood-2011-11-389908","journal-title":"Blood"},{"key":"4_CR5","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.beha.2016.09.003","volume":"30","author":"AJ Arribas","year":"2017","unstructured":"Arribas AJ, Bertoni F (2017) Methylation patterns in marginal zone lymphoma. Best Pract Res Clin Haematol 30:24\u201331. https:\/\/doi.org\/10.1016\/j.beha.2016.09.003","journal-title":"Best Pract Res Clin Haematol"},{"key":"4_CR6","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1620\/tjem.228.223.Correspondence","volume":"228","author":"N Asano","year":"2012","unstructured":"Asano N, Iijima K, Terai S et al (2012) Eradication therapy is effective for Helicobacter pylori-negative gastric mucosa-associated lymphoid tissue lymphoma. Tohoku J Exp Med 228:223\u2013227. https:\/\/doi.org\/10.1620\/tjem.228.223.Correspondence","journal-title":"Tohoku J Exp Med"},{"issue":"2","key":"4_CR7","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.tibs.2007.10.006","volume":"33","author":"S Backert","year":"2008","unstructured":"Backert S, Feller SM, Wessler S (2008) Emerging roles of Abl family tyrosine kinases in microbial pathogenesis. Trends Biochem Sci 33(2):80\u201390. https:\/\/doi.org\/10.1016\/j.tibs.2007.10.006","journal-title":"Trends Biochem Sci"},{"key":"4_CR8","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/j.tim.2010.08.003","volume":"18","author":"S Backert","year":"2010","unstructured":"Backert S, Naumann M (2010) What a disorder: proinflammatory signaling pathways induced by Helicobacter pylori. Trends Microbiol 18:479\u2013486. https:\/\/doi.org\/10.1016\/j.tim.2010.08.003","journal-title":"Trends Microbiol"},{"key":"4_CR9","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1007\/978-3-319-75241-9_8","volume":"413","author":"S Backert","year":"2017","unstructured":"Backert S, Haas R, Gerhard M, Naumann M (2017) The Helicobacter pylori type IV secretion system encoded by the cag Pathogenicity Island: architecture, function, and signaling. Curr Top Microbiol Immunol 413:187\u2013220. https:\/\/doi.org\/10.1007\/978-3-319-75241-9_8","journal-title":"Curr Top Microbiol Immunol"},{"key":"4_CR10","doi-asserted-by":"publisher","first-page":"184","DOI":"10.3324\/haematol.2011.052639","volume":"97","author":"M Baens","year":"2012","unstructured":"Baens M, Ferreiro JF, Tousseyn T et al (2012) t(X;14)(p 11.4;q32.33) is recurrent in marginal zone lymphoma and up-regulates GPR34. Haematologica 97:184\u2013188. https:\/\/doi.org\/10.3324\/haematol.2011.052639","journal-title":"Haematologica"},{"key":"4_CR11","doi-asserted-by":"publisher","first-page":"5270","DOI":"10.1158\/0008-5472.CAN-05-4590","volume":"66","author":"M Baens","year":"2006","unstructured":"Baens M, Fevery S, Sagaert X et al (2006) Selective expansion of marginal zone B cells in Emicro-API2-MALT1 mice is linked to enhanced IkappaB kinase gamma polyubiquitination. Cancer Res 66:5270\u20135277. https:\/\/doi.org\/10.1158\/0008-5472.CAN-05-4590","journal-title":"Cancer Res"},{"key":"4_CR12","doi-asserted-by":"publisher","first-page":"1433","DOI":"10.1016\/S0002-9440(10)65012-2","volume":"156","author":"M Baens","year":"2000","unstructured":"Baens M, Maes B, Steyls A et al (2000) The product of the t(11;18), an API2-MLT fusion, marks nearly half of gastric MALT type lymphomas without large cell proliferation. Am J Pathol 156:1433\u20131439. https:\/\/doi.org\/10.1016\/S0002-9440(10)65012-2","journal-title":"Am J Pathol"},{"key":"4_CR13","doi-asserted-by":"publisher","first-page":"8820","DOI":"10.1038\/297365a0","volume":"61","author":"AH Banham","year":"2001","unstructured":"Banham AH, Beasley N, Campo E et al (2001) The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p. Cancer Res 61:8820\u20138829. https:\/\/doi.org\/10.1038\/297365a0","journal-title":"Cancer Res"},{"key":"4_CR14","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1158\/1078-0432.1065.11.3","volume":"11","author":"AH Banham","year":"2005","unstructured":"Banham AH, Connors JM, Brown PJ et al (2005) Expression of the FOXP1 transcription factor is strongly associated with inferior survival in patients with diffuse large B-cell lymphoma. Clin Cancer Res 11:1065\u20131072","journal-title":"Clin Cancer Res"},{"key":"4_CR15","doi-asserted-by":"publisher","first-page":"2933","DOI":"10.1182\/blood-2004-03-1209","volume":"104","author":"SL Barrans","year":"2004","unstructured":"Barrans SL, Fenton JAL, Banham A et al (2004) Strong expression of FOXP1 identifies a distinct subset of diffuse large B-cell lymphoma (DLBCL) patients with poor outcome. Blood 104:2933\u20132935. https:\/\/doi.org\/10.1182\/blood-2004-03-1209","journal-title":"Blood"},{"key":"4_CR16","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1002\/gcc.1150","volume":"31","author":"TFE Barth","year":"2001","unstructured":"Barth TFE, Bentz M, Leithuser F et al (2001) Molecular-cytogenetic comparison of mucosa-associated marginal zone B-cell lymphoma and large B-cell lymphoma arising in the gastro-intestinal tract. Genes Chromosom Cancer 31:316\u2013325. https:\/\/doi.org\/10.1002\/gcc.1150","journal-title":"Genes Chromosom Cancer"},{"key":"4_CR17","doi-asserted-by":"publisher","first-page":"806","DOI":"10.1111\/j.1469-0691.2009.02960.x","volume":"15","author":"C Belair","year":"2009","unstructured":"Belair C, Belair C, Darfeuille F et al (2009) Helicobacter pylori and gastric cancer: possible role of microRNAs in this intimate relationship. Clin Microbiol Infect 15:806\u2013812. https:\/\/doi.org\/10.1111\/j.1469-0691.2009.02960.x","journal-title":"Clin Microbiol Infect"},{"key":"4_CR18","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.it.2004.03.008","volume":"25","author":"G Bonizzi","year":"2004","unstructured":"Bonizzi G, Karin M (2004) The two NF-\u03baB activation pathways and their role in innate and adaptive immunity. Trends Immunol 25:280\u2013288. https:\/\/doi.org\/10.1016\/j.it.2004.03.008","journal-title":"Trends Immunol"},{"key":"4_CR19","doi-asserted-by":"publisher","first-page":"3723","DOI":"10.4049\/jimmunol.1402254","volume":"194","author":"F Bornancin","year":"2015","unstructured":"Bornancin F, Renner F, Touil R et al (2015) Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation. J Immunol 194:3723\u20133734. https:\/\/doi.org\/10.4049\/jimmunol.1402254","journal-title":"J Immunol"},{"key":"4_CR20","doi-asserted-by":"publisher","first-page":"9300","DOI":"10.1073\/pnas.0409873102","volume":"102","author":"S Brandt","year":"2005","unstructured":"Brandt S, Kwok T, Hartig R, K\u00f6nig W, Backert S (2005) NF-B activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein. Proc Natl Acad Sci 102:9300\u20139305. https:\/\/doi.org\/10.1073\/pnas.0409873102","journal-title":"Proc Natl Acad Sci"},{"key":"4_CR21","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1007\/s00417-011-1885-4","volume":"250","author":"J Cai","year":"2012","unstructured":"Cai J, Liu X, Cheng J et al (2012) MicroRNA-200 is commonly repressed in conjunctival MALT lymphoma, and targets cyclin E2. Graefes Arch Clin Exp Ophthalmol 250:523\u2013531. https:\/\/doi.org\/10.1007\/s00417-011-1885-4","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"4_CR22","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1111\/1469-0691.12545","volume":"20","author":"S Coeuret","year":"2014","unstructured":"Coeuret S, de La Blanchardi\u00e8re A, Saguet-Rysanek V et al (2014) Campylobacter coli cultured from the stools of a patient with immunoproliferative small intestinal disease. Clin Microbiol Infect 20:908\u2013911. https:\/\/doi.org\/10.1111\/1469-0691.12545","journal-title":"Clin Microbiol Infect"},{"key":"4_CR23","doi-asserted-by":"publisher","first-page":"1159","DOI":"10.1016\/0016-5085(91)90063-Q","volume":"101","author":"SB Cogliatti","year":"1991","unstructured":"Cogliatti SB, Schmid U, Schumacher U et al (1991) Primary B-cell gastric lymphoma: a clinicopathological study of 145 patients. Gastroenterology 101:1159\u20131170. https:\/\/doi.org\/10.1016\/0016-5085(91)90063-Q","journal-title":"Gastroenterology"},{"key":"4_CR24","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1093\/annonc\/mdq416","volume":"22","author":"A Conconi","year":"2011","unstructured":"Conconi A, Martinelli G, Lopez-Guillermo A et al (2011) Clinical activity of bortezomib in relapsed\/refractory MALT lymphomas: results of a phase II study of the international extranodal lymphoma study group (IELSG). Ann Oncol 22:689\u2013695. https:\/\/doi.org\/10.1093\/annonc\/mdq416","journal-title":"Ann Oncol"},{"key":"4_CR25","first-page":"259","volume-title":"WHO classification of tumours of haematopoietic and lymphoid tissues, Revised 4t","author":"JR Cook","year":"2017","unstructured":"Cook JR, M\u00fcller-Hermelink HK, Isaacson PG et al (2017) Extranodal marginal zone lymphoma of lymphoma of- mucosa-associated lymphoid tissue (MALT) lymphoma. In: Swerdlow SH, Campo E, Harris NL et al (eds) WHO classification of tumours of haematopoietic and lymphoid tissues, Revised 4t. IARC, Lyon, pp 259\u2013262"},{"key":"4_CR26","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1038\/ni1561","volume":"9","author":"B Coornaert","year":"2008","unstructured":"Coornaert B, Baens M, Heyninck K et al (2008) T cell antigen receptor stimulation induces MALT1 paracaspase\u2014mediated cleavage of the NF-\u03baB inhibitor A20. Nat Immunol 9:263\u2013271. https:\/\/doi.org\/10.1038\/ni1561","journal-title":"Nat Immunol"},{"key":"4_CR27","doi-asserted-by":"publisher","first-page":"1656","DOI":"10.1136\/gut.52.11.1655","volume":"52","author":"C Copie-Bergman","year":"2003","unstructured":"Copie-Bergman C, Gaulard P, Lavergne-Slove A et al (2003) Proposal for a new histological grading system for post-treatment evaluation of gastric MALT lymphoma. Gut 52:1656. https:\/\/doi.org\/10.1136\/gut.52.11.1655","journal-title":"Gut"},{"key":"4_CR28","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1038\/nature01322","volume":"420","author":"LM Coussens","year":"2009","unstructured":"Coussens LM, Werb Z (2009) Inflammation and cancer. Nature 420:860\u2013867. https:\/\/doi.org\/10.1038\/nature01322","journal-title":"Nature"},{"key":"4_CR29","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1182\/blood-2009-06-228015","volume":"115","author":"VJ Craig","year":"2010","unstructured":"Craig VJ, Arnold I, Gerke C et al (2010) Gastric MALT lymphoma B cells express polyreactive, somatically mutated immunoglobulins. Blood 115:581\u2013591. https:\/\/doi.org\/10.1182\/blood-2009-06-228015","journal-title":"Blood"},{"key":"4_CR30","doi-asserted-by":"crossref","first-page":"3578","DOI":"10.1182\/blood.V96.10.3578","volume":"96","author":"V Re De","year":"2000","unstructured":"De Re V, De Vita S, Marzotto A et al (2000) Sequence analysis of the immunoglobulin antigen receptor of hepatitis C virus-associated non-Hodgkin lymphomas suggests that the malignant cells are derived from the rheumatoid factor-producing cells that occur mainly in type II cryoglobulinemia. Blood 96:3578\u20133584","journal-title":"Blood"},{"key":"4_CR31","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.beha.2017.11.001","volume":"31","author":"I Defrancesco","year":"2018","unstructured":"Defrancesco I, Arcaini L (2018) Overview on the management of non-gastric MALT lymphomas. Best Pract Res Clin Haematol 31:57\u201364. https:\/\/doi.org\/10.1016\/j.beha.2017.11.001","journal-title":"Best Pract Res Clin Haematol"},{"key":"4_CR32","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3109\/10428194.2012.723211","volume":"8194","author":"A Degroote","year":"2012","unstructured":"Degroote A, Knippenberg L, Vander Borght S et al (2012) Analysis of microsatellite instability in gastric mucosa-associated lymphoid tissue lymphoma. Leuk Lymphoma 8194:1\u20137. https:\/\/doi.org\/10.3109\/10428194.2012.723211","journal-title":"Leuk Lymphoma"},{"key":"4_CR33","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.molmed.2015.12.004","volume":"22","author":"A Demeyer","year":"2016","unstructured":"Demeyer A, Staal J, Beyaert R (2016) Targeting MALT1 proteolytic activity in immunity, inflammation and disease: good or bad? Trends Mol Med 22:135\u2013150. https:\/\/doi.org\/10.1016\/j.molmed.2015.12.004","journal-title":"Trends Mol Med"},{"key":"4_CR34","doi-asserted-by":"crossref","first-page":"3601","DOI":"10.1182\/blood.V93.11.3601","volume":"93","author":"J Dierlamm","year":"1999","unstructured":"Dierlamm J, Baens M, Wlodarska I et al (1999) The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas. Blood 93:3601\u20133609","journal-title":"Blood"},{"key":"4_CR35","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1016\/0140-6736(92)90280-G","volume":"339","author":"C Doglioni","year":"1992","unstructured":"Doglioni C, Wotherspoon AC, Moschini A et al (1992) High incidence of primary gastric lymphoma in northeastern Italy. Lancet (London, England) 339:834\u2013835","journal-title":"Lancet (London, England)"},{"key":"4_CR36","doi-asserted-by":"publisher","first-page":"26029","DOI":"10.1074\/jbc.M513057200","volume":"281","author":"W Dong","year":"2006","unstructured":"Dong W, Liu Y, Peng J et al (2006) The IRAK-1-BCL10-MALT1-TRAF6-TAK1 cascade mediates signaling to NF-\u03baB from toll-like receptor 4. J Biol Chem 281:26029\u201326040. https:\/\/doi.org\/10.1074\/jbc.M513057200","journal-title":"J Biol Chem"},{"key":"4_CR37","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1093\/annonc\/mds643","volume":"24","author":"M Dreyling","year":"2013","unstructured":"Dreyling M, Thieblemont C, Gallamini A et al (2013) Esmo consensus conferences: guidelines on malignant lymphoma. Part 2: marginal zone lymphoma, mantle cell lymphoma, peripheral T-cell lymphoma. Ann Oncol 24:857\u2013877. https:\/\/doi.org\/10.1093\/annonc\/mds643","journal-title":"Ann Oncol"},{"key":"4_CR38","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.semcancer.2016.07.003","volume":"39","author":"M Du","year":"2016","unstructured":"Du M (2016) MALT lymphoma: a paradigm of NF-\u03baB dysregulation. Semin Cancer Biol 39:49\u201360. https:\/\/doi.org\/10.1016\/j.semcancer.2016.07.003","journal-title":"Semin Cancer Biol"},{"key":"4_CR39","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.1016\/S0016-5085(97)70028-3","volume":"112","author":"M Eck","year":"1997","unstructured":"Eck M, Schmausser B, Haas R et al (1997) MALT-type lymphoma of the stomach is associated with Helicobacter pylori strains expressing the CagA protein. Gastroenterology 112:1482\u20131486. https:\/\/doi.org\/10.1016\/S0016-5085(97)70028-3","journal-title":"Gastroenterology"},{"key":"4_CR40","doi-asserted-by":"publisher","unstructured":"Fern\u00e1ndez C, Bellosillo B, Ferraro M et al (2017) MicroRNAs 142\u20133p, miR-155 and miR-203 are deregulated in gastric MALT lymphomas compared to chronic gastritis. Cancer Genomics Proteomics 14:75\u201382. https:\/\/doi.org\/10.21873\/cgp.20020","DOI":"10.21873\/cgp.20020"},{"key":"4_CR41","doi-asserted-by":"publisher","first-page":"670","DOI":"10.3324\/haematol.12221","volume":"93","author":"BI Ferreira","year":"2008","unstructured":"Ferreira BI, Garc\u00eda JF, Suela J et al (2008) Comparative genome profiling across subtypes of low-grade B-cell lymphoma identifies type-specific and common aberrations that target genes with a role in B-cell neoplasia. Haematologica 93:670\u2013679. https:\/\/doi.org\/10.3324\/haematol.12221","journal-title":"Haematologica"},{"key":"4_CR42","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1038\/nrclinonc.2009.147","volume":"6","author":"AJM Ferreri","year":"2009","unstructured":"Ferreri AJM, Dolcetti R, Magnino S et al (2009) Chlamydial infection: The link with ocular adnexal lymphomas. Nat Rev Clin Oncol 6:658\u2013669. https:\/\/doi.org\/10.1038\/nrclinonc.2009.147","journal-title":"Nat Rev Clin Oncol"},{"key":"4_CR43","doi-asserted-by":"publisher","first-page":"1191","DOI":"10.1053\/gast.2000.19579","volume":"119","author":"W Fischbach","year":"2000","unstructured":"Fischbach W, Dragosics B, Kolve-Goebeler ME et al (2000) Primary gastric B-cell lymphoma: results of a prospective multicenter study. Gastroenterology 119:1191\u20131202. https:\/\/doi.org\/10.1053\/gast.2000.19579","journal-title":"Gastroenterology"},{"key":"4_CR44","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1136\/gut.53.1.34","volume":"53","author":"W Fischbach","year":"2004","unstructured":"Fischbach W, Goebeler-Kolve M-E, Dragosics B et al (2004) Long term outcome of patients with gastric marginal zone B cell lymphoma of mucosa associated lymphoid tissue (MALT) following exclusive Helicobacter pylori eradication therapy: experience from a large prospective series. Gut 53:34\u201337. https:\/\/doi.org\/10.1136\/gut.53.1.34","journal-title":"Gut"},{"key":"4_CR45","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1136\/gut.2006.096420","volume":"56","author":"W Fischbach","year":"2007","unstructured":"Fischbach W, Goebeler ME, Ruskone-Fourmestraux A et al (2007) Most patients with minimal histological residuals of gastric MALT lymphoma after successful eradication of Helicobacter pylori can be managed safely by a watch and wait strategy: experience from a large international series. Gut 56:1685\u20131687. https:\/\/doi.org\/10.1136\/gut.2006.096420","journal-title":"Gut"},{"key":"4_CR46","doi-asserted-by":"publisher","first-page":"E117","DOI":"10.1002\/ijc.27774","volume":"132","author":"L Flossbach","year":"2013","unstructured":"Flossbach L, Holzmann K, Mattfeldt T et al (2013) High-resolution genomic profiling reveals clonal evolution and competition in gastrointestinal marginal zone B-cell lymphoma and its large cell variant. Int J Cancer 132:E117\u2013127. https:\/\/doi.org\/10.1002\/ijc.27774","journal-title":"Int J Cancer"},{"key":"4_CR47","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1002\/gcc.20464","volume":"46","author":"N Fukuhara","year":"2007","unstructured":"Fukuhara N, Nakamura T, Nakagawa M et al (2007) Chromosomal imbalances are associated with outcome of Helicobacter pylori eradication in t(11;18)(q21;q21) negative gastric mucosa-associated lymphoid tissue lymphomas. Genes Chromosomes Cancer 46:784\u2013790. https:\/\/doi.org\/10.1002\/gcc.20464","journal-title":"Genes Chromosomes Cancer"},{"key":"4_CR48","first-page":"51","volume":"11","author":"N Gebauer","year":"2014","unstructured":"Gebauer N, Kuba J, Senft A et al (2014) MicroRNA-150 Is up-regulated in extranodal marginal zone lymphoma of MALT type. Cancer Genomics Proteomics 11:51\u201356","journal-title":"Cancer Genomics Proteomics"},{"key":"4_CR49","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fimmu.2018.01539","volume":"9","author":"T Gehring","year":"2018","unstructured":"Gehring T, Seeholzer T, Krappmann D (2018) BCL10\u2014Bridging CARDs to immune activation. Front Immunol 9:1\u201310. https:\/\/doi.org\/10.3389\/fimmu.2018.01539","journal-title":"Front Immunol"},{"key":"4_CR50","doi-asserted-by":"publisher","first-page":"2463","DOI":"10.1073\/pnas.95.5.2463","volume":"95","author":"T Goossens","year":"1998","unstructured":"Goossens T, Klein U, Kuppers R (1998) Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease. Proc Natl Acad Sci 95:2463\u20132468. https:\/\/doi.org\/10.1073\/pnas.95.5.2463","journal-title":"Proc Natl Acad Sci"},{"key":"4_CR51","doi-asserted-by":"publisher","first-page":"14596","DOI":"10.1073\/pnas.1105020108","volume":"108","author":"S Hailfinger","year":"2011","unstructured":"Hailfinger S, Nogai H, Pelzer C et al (2011) Malt1-dependent RelB cleavage promotes canonical NF-B activation in lymphocytes and lymphoma cell lines. Proc Natl Acad Sci 108:14596\u201314601. https:\/\/doi.org\/10.1073\/pnas.1105020108","journal-title":"Proc Natl Acad Sci"},{"key":"4_CR52","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1159\/000212058","volume":"26","author":"SL Han","year":"2009","unstructured":"Han SL, Wu XL, Wan L et al (2009) FOXP1 expression predicts polymorphic histology and poor prognosis in gastric mucosa-associated lymphoid tissue lymphomas. Dig Surg 26:156\u2013162. https:\/\/doi.org\/10.1159\/000212058","journal-title":"Dig Surg"},{"key":"4_CR53","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1182\/blood-2003-05-1545","volume":"103","author":"CP Hans","year":"2004","unstructured":"Hans CP, Weisenburger DD, Greiner TC et al (2004) Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray. Blood 103:275\u2013282. https:\/\/doi.org\/10.1182\/blood-2003-05-1545","journal-title":"Blood"},{"key":"4_CR54","doi-asserted-by":"publisher","first-page":"1300","DOI":"10.1038\/sj.leu.2404244","volume":"20","author":"E Haralambieva","year":"2006","unstructured":"Haralambieva E, Adam P, Ventura R et al (2006) Genetic rearrangement of FOXP1 is predominantly detected in a subset of diffuse large B-cell lymphomas with extranodal presentation. Leukemia 20:1300\u20131333. https:\/\/doi.org\/10.1038\/sj.leu.2404244","journal-title":"Leukemia"},{"key":"4_CR55","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.celrep.2015.08.074","volume":"13","author":"ML Hartung","year":"2015","unstructured":"Hartung ML, Gruber DC, Koch KN et al (2015) H. pylori-induced DNA strand breaks are introduced by nucleotide excision repair endonucleases and promote NF-\u03baB target gene expression. Cell Rep 13:70\u201379. https:\/\/doi.org\/10.1016\/j.celrep.2015.08.074","journal-title":"Cell Rep"},{"key":"4_CR56","doi-asserted-by":"publisher","first-page":"1865","DOI":"10.1016\/j.ejca.2009.03.010","volume":"45","author":"S Hellmig","year":"2009","unstructured":"Hellmig S, Bartscht T, Fischbach W et al (2009) Germline variations of the MALT1 gene as risk factors in the development of primary gastric B-cell lymphoma. Eur J Cancer 45:1865\u20131870. https:\/\/doi.org\/10.1016\/j.ejca.2009.03.010","journal-title":"Eur J Cancer"},{"key":"4_CR57","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1111\/j.1523-5378.2006.00460.x","volume":"11","author":"SS Hong","year":"2006","unstructured":"Hong SS, Jung HY, Choi KD et al (2006) A prospective analysis of low-grade gastric MALT lymphoma after Helicobacter pylori eradication. Helicobacter 11:569\u2013573. https:\/\/doi.org\/10.1111\/j.1523-5378.2006.00460.x","journal-title":"Helicobacter"},{"key":"4_CR58","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.bbrc.2005.06.058","volume":"334","author":"Y Hosokawa","year":"2005","unstructured":"Hosokawa Y, Suzuki H, Nakagawa M et al (2005) API2-MALT1 fusion protein induces transcriptional activation of the API2 gene through NF-\u03baB binding elements: Evidence for a positive feed-back loop pathway resulting in unremitting NF-\u03baB activation. Biochem Biophys Res Commun 334:51\u201360. https:\/\/doi.org\/10.1016\/j.bbrc.2005.06.058","journal-title":"Biochem Biophys Res Commun"},{"key":"4_CR59","first-page":"285","volume":"142","author":"T Hussell","year":"1993","unstructured":"Hussell T, Isaacson PG, Crabtree JE et al (1993a) Immunoglobulin specificity of low grade B cell gastrointestinal lymphoma of mucosa-associated lymphoid tissue (MALT) type. Am J Pathol 142:285\u2013292","journal-title":"Am J Pathol"},{"key":"4_CR60","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1016\/0140-6736(93)91408-E","volume":"342","author":"T Hussell","year":"1993","unstructured":"Hussell T, Isaacson PG, Spencer J, Crabtree JE (1993b) The response of cells from low-grade B-cell gastric lymphomas of mucosa-associated lymphoid tissue to Helicobacter pylori. Lancet 342:571\u2013574. https:\/\/doi.org\/10.1016\/0140-6736(93)91408-E","journal-title":"Lancet"},{"key":"4_CR61","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1016\/j.micpath.2018.01.040","volume":"116","author":"A Jafarzadeh","year":"2018","unstructured":"Jafarzadeh A, Larussa T, Nemati M, Jalapour S (2018) T cell subsets play an important role in the determination of the clinical outcome of Helicobacter pylori infection. Microb Pathog 116:227\u2013236. https:\/\/doi.org\/10.1016\/j.micpath.2018.01.040","journal-title":"Microb Pathog"},{"key":"4_CR62","doi-asserted-by":"publisher","first-page":"3872","DOI":"10.1200\/JCO.2002.05.117","volume":"20","author":"G J\u00e4ger","year":"2002","unstructured":"J\u00e4ger G, Neumeister P, Brezinschek R et al (2002) Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type with cladribine: a phase II study. J Clin Oncol 20:3872\u20133877. https:\/\/doi.org\/10.1200\/JCO.2002.05.117","journal-title":"J Clin Oncol"},{"key":"4_CR63","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1002\/gcc.20264","volume":"45","author":"J Jiang","year":"2006","unstructured":"Jiang J, Eun JL, Schmittgen TD (2006) Increased expression of microRNA-155 in Epstein-Barr virus transformed lymphoblastoid cell lines. Genes Chromosom Cancer 45:103\u2013106. https:\/\/doi.org\/10.1002\/gcc.20264","journal-title":"Genes Chromosom Cancer"},{"key":"4_CR64","doi-asserted-by":"publisher","first-page":"1967","DOI":"10.1038\/sj.leu.2401918","volume":"14","author":"J Kalla","year":"2000","unstructured":"Kalla J, Stilgenbauer S, Schaffner C et al (2000) Heterogeneity of the API2-MALT1 gene rearrangement in MALT-type lymphoma. Leukemia 14:1967\u20131974. https:\/\/doi.org\/10.1038\/sj.leu.2401918","journal-title":"Leukemia"},{"key":"4_CR65","doi-asserted-by":"publisher","first-page":"3519","DOI":"10.1128\/IAI.01314-05","volume":"74","author":"M Kaparakis","year":"2006","unstructured":"Kaparakis M, Laurie KL, Wijburg O et al (2006) CD4+ CD25+ regulatory T cells modulate the T-cell and antibody responses in Helicobacter-Infected BALB\/c mice. Infect Immun 74:3519\u20133529. https:\/\/doi.org\/10.1128\/IAI.01314-05","journal-title":"Infect Immun"},{"key":"4_CR66","doi-asserted-by":"publisher","first-page":"353","DOI":"10.3324\/haematol.2012.065995","volume":"98","author":"B Kiesewetter","year":"2013","unstructured":"Kiesewetter B, Troch M, Dolak W et al (2013) A phase II study of lenalidomide in patients with extranodal marginal zone B-cell lymphoma of the mucosa associated lymphoid tissue (MALT lymphoma). Haematologica 98:353\u2013356. https:\/\/doi.org\/10.3324\/haematol.2012.065995","journal-title":"Haematologica"},{"key":"4_CR67","doi-asserted-by":"publisher","first-page":"e3","DOI":"10.1042\/BJ20120414","volume":"444","author":"D Kirchhofer","year":"2012","unstructured":"Kirchhofer D, Vucic D (2012) Protease activity of MALT1: a mystery unravelled. Biochem J 444:e3\u2013e5. https:\/\/doi.org\/10.1042\/BJ20120414","journal-title":"Biochem J"},{"key":"4_CR68","doi-asserted-by":"publisher","first-page":"3874","DOI":"10.1200\/JCO.2001.19.18.3874","volume":"19","author":"P Koch","year":"2001","unstructured":"Koch P, del Valle F, Berdel WE et al (2001) Primary gastrointestinal non-Hodgkin\u2019s lymphoma: II. Combined surgical and conservative or conservative management only in localized gastric lymphoma\u2013results of the prospective German Multicenter Study GIT NHL 01\/92. J Clin Oncol 19:3874\u20133883. https:\/\/doi.org\/10.1200\/JCO.2001.19.18.3874","journal-title":"J Clin Oncol"},{"key":"4_CR69","doi-asserted-by":"publisher","first-page":"7050","DOI":"10.1200\/JCO.2005.04.031","volume":"23","author":"P Koch","year":"2005","unstructured":"Koch P, Probst A, Berdel WE et al (2005) Treatment results in localized primary gastric lymphoma: data of patients registered within the German multicenter study (GIT NHL 02\/96). J Clin Oncol 23:7050\u20137059. https:\/\/doi.org\/10.1200\/JCO.2005.04.031","journal-title":"J Clin Oncol"},{"key":"4_CR70","doi-asserted-by":"publisher","first-page":"547","DOI":"10.3892\/ijo","volume":"35","author":"T Kondo","year":"2009","unstructured":"Kondo T, Oka T, Sato H et al (2009) Accumulation of aberrant CpG hypermethylation by Helicobacter pylori infection promotes development and progression of gastric MALT lymphoma. Int J Oncol 35:547\u2013557. https:\/\/doi.org\/10.3892\/ijo","journal-title":"Int J Oncol"},{"key":"4_CR71","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.semcancer.2016.05.002","volume":"39","author":"D Krappmann","year":"2016","unstructured":"Krappmann D, Vincendeau M (2016) Mechanisms of NF-\u03baB deregulation in lymphoid malignancies. Semin Cancer Biol 39:3\u201314. https:\/\/doi.org\/10.1016\/j.semcancer.2016.05.002","journal-title":"Semin Cancer Biol"},{"key":"4_CR72","doi-asserted-by":"publisher","first-page":"e125","DOI":"10.1038\/bcj.2013.22","volume":"3","author":"S-H Kuo","year":"2013","unstructured":"Kuo S-H, Chen L-T, Lin C-W et al (2013) Detection of the Helicobacter pylori CagA protein in gastric mucosa-associated lymphoid tissue lymphoma cells: clinical and biological significance. Blood Cancer J 3:e125. https:\/\/doi.org\/10.1038\/bcj.2013.22","journal-title":"Blood Cancer J"},{"key":"4_CR73","doi-asserted-by":"publisher","first-page":"1064","DOI":"10.3324\/haematol.2011.040402","volume":"96","author":"I Kwee","year":"2011","unstructured":"Kwee I, Rancoita PMV, Rinaldi A et al (2011) Genomic profiles of MALT lymphomas: variability across anatomical sites. Haematologica 96:1064\u20131066. https:\/\/doi.org\/10.3324\/haematol.2011.040402","journal-title":"Haematologica"},{"key":"4_CR74","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1056\/NEJMoa031887","volume":"350","author":"M Lecuit","year":"2004","unstructured":"Lecuit M, Abachin E, Martin A et al (2004) Immunoproliferative small intestinal disease associated with Campylobacter jejuni. N Engl J Med 350:239\u2013248. https:\/\/doi.org\/10.1056\/NEJMoa031887","journal-title":"N Engl J Med"},{"key":"4_CR75","doi-asserted-by":"publisher","first-page":"940","DOI":"10.3109\/10428194.2012.729832","volume":"54","author":"M L\u00e9vy","year":"2013","unstructured":"L\u00e9vy M, Copie-Bergman C, Amiot A et al (2013) Rituximab and chlorambucil versus rituximab alone in gastric mucosa-associated lymphoid tissue lymphoma according to t(11;18) status: a monocentric non-randomized observational study. Leuk Lymphoma 54:940\u2013944. https:\/\/doi.org\/10.3109\/10428194.2012.729832","journal-title":"Leuk Lymphoma"},{"key":"4_CR76","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1038\/nri910","volume":"2","author":"Q Li","year":"2002","unstructured":"Li Q, Verma IM (2002) NF-\u03baB regulation in the immune system. Nat Rev Immunol 2:725\u2013734. https:\/\/doi.org\/10.1038\/nri910","journal-title":"Nat Rev Immunol"},{"key":"4_CR77","doi-asserted-by":"publisher","first-page":"1621","DOI":"10.1038\/cdd.2017.89","volume":"24","author":"MCC Lim","year":"2017","unstructured":"Lim MCC, Maubach G, Sokolova O, Feige MH, Diezko R, Buchbinder J, Backert S, Schl\u00fcter D, Lavrik IN, Naumann M (2017) Pathogen-induced ubiquitin-editing enzyme A20 bifunctionally shuts off NF-\u03baB and caspase-8-dependent apoptotic cell death. Cell Death Differ 24:1621\u20131631. https:\/\/doi.org\/10.1038\/cdd.2017.89","journal-title":"Cell Death Differ"},{"key":"4_CR78","doi-asserted-by":"publisher","first-page":"5740","DOI":"10.1158\/0008-5472.CAN-09-4690","volume":"70","author":"W-C Lin","year":"2010","unstructured":"Lin W-C, Tsai H-F, Kuo S-H et al (2010) Translocation of Helicobacter pylori CagA into Human B lymphocytes, the origin of mucosa-associated lymphoid tissue lymphoma. Cancer Res 70:5740\u20135748. https:\/\/doi.org\/10.1158\/0008-5472.CAN-09-4690","journal-title":"Cancer Res"},{"key":"4_CR79","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/S0140-6736(00)03571-6","volume":"357","author":"H Liu","year":"2001","unstructured":"Liu H, Ruskon-Fourmestraux A, Lavergne-Slove A et al (2001a) Resistance of t(11;18) positive gastric mucosa-associated lymphoid tissue lymphoma to Helicobacter pylori eradication therapy. Lancet (London, England) 357:39\u201340. https:\/\/doi.org\/10.1016\/S0140-6736(00)03571-6","journal-title":"Lancet (London, England)"},{"key":"4_CR80","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1182\/blood.V98.4.1182","volume":"98","author":"H Liu","year":"2001","unstructured":"Liu H, Ye H, Dogan A et al (2001b) T(11;18)(q21;q21) is associated with advanced mucosa-associated lymphoid tissue lymphoma that expresses nuclear BCL10. Blood 98:1182\u20131187","journal-title":"Blood"},{"key":"4_CR81","doi-asserted-by":"publisher","first-page":"5643","DOI":"10.1038\/sj.onc.1210342","volume":"26","author":"PC Lucas","year":"2007","unstructured":"Lucas PC, Kuffa P, Gu S et al (2007) A dual role for the API2 moiety in API2-MALT1-dependent NF-\u03baB activation: heterotypic oligomerization and TRAF2 recruitment. Oncogene 26:5643\u20135654. https:\/\/doi.org\/10.1038\/sj.onc.1210342","journal-title":"Oncogene"},{"key":"4_CR82","doi-asserted-by":"publisher","first-page":"19012","DOI":"10.1074\/jbc.M009984200","volume":"276","author":"PC Lucas","year":"2001","unstructured":"Lucas PC, Yonezumi M, Inohara N et al (2001) Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway. J Biol Chem 276:19012\u201319019. https:\/\/doi.org\/10.1074\/jbc.M009984200","journal-title":"J Biol Chem"},{"key":"4_CR83","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1038\/nri799","volume":"2","author":"F Martin","year":"2002","unstructured":"Martin F, Kearney JF (2002) Marginal-zone B cells. Nat Rev Immunol 2:323\u2013335. https:\/\/doi.org\/10.1038\/nri799","journal-title":"Nat Rev Immunol"},{"issue":"5","key":"4_CR84","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.1016\/j.jaci.2013.10.045","volume":"133","author":"ML McKinnon","year":"2014","unstructured":"McKinnon ML, Rozmus J, Fung SY et al (2014) Combined immunodeficiency associated with homozygous MALT1 mutations. J Allergy Clin Immunol 133(5):1458\u20131462. https:\/\/doi.org\/10.1016\/j.jaci.2013.10.045","journal-title":"J Allergy Clin Immunol"},{"key":"4_CR85","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1038\/modpathol.3800505","volume":"19","author":"KO Min","year":"2006","unstructured":"Min KO, Seo EJ, Kwon HJ et al (2006) Methylation of p16(INK4A) and p57(KIP2) are involved in the development and progression of gastric MALT lymphomas. Mod Pathol 19:141\u2013148. https:\/\/doi.org\/10.1038\/modpathol.3800505","journal-title":"Mod Pathol"},{"key":"4_CR86","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1177\/2050640615612934","volume":"4","author":"J Moleiro","year":"2016","unstructured":"Moleiro J, Ferreira S, Lage P, Dias Pereira A (2016) Gastric malt lymphoma: Analysis of a series of consecutive patients over 20\u00a0years. United Eur Gastroenterol J 4:395\u2013402. https:\/\/doi.org\/10.1177\/2050640615612934","journal-title":"United Eur Gastroenterol J"},{"key":"4_CR87","doi-asserted-by":"publisher","unstructured":"Morgner A, Lehn N, Andersen LP et al (2000) Helicobacter heilmannii\u2014associated primary gastric low-grade. Gastroenterology 5:821\u2013828. https:\/\/doi.org\/10.1053\/gg.2000.7032","DOI":"10.1053\/gg.2000.7032"},{"key":"4_CR88","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1016\/S0002-9440(10)64948-6","volume":"156","author":"M Motegi","year":"2000","unstructured":"Motegi M, Yonezumi M, Suzuki H et al (2000) API2-MALT1 chimeric transcripts involved in mucosa-associated lymphoid tissue type lymphoma predict heterogeneous products. Am J Pathol 156:807\u2013812. https:\/\/doi.org\/10.1016\/S0002-9440(10)64948-6","journal-title":"Am J Pathol"},{"key":"4_CR89","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1053\/hupa.2003.98","volume":"34","author":"HK M\u00fcller-Hermelink","year":"2003","unstructured":"M\u00fcller-Hermelink HK (2003) Genetic and molecular genetic studies in the diagnosis of B-cell lymphomas: marginal zone lymphomas. Hum Pathol 34:336\u2013340. https:\/\/doi.org\/10.1053\/hupa.2003.98","journal-title":"Hum Pathol"},{"key":"4_CR90","doi-asserted-by":"publisher","first-page":"4210","DOI":"10.1182\/blood-2004-12-4785","volume":"106","author":"M Nakagawa","year":"2005","unstructured":"Nakagawa M, Hosokawa Y, Yonezumi M et al (2005) MALT1 contains nuclear export signals and regulates cytoplasmic localization of BCL10. Blood 106:4210\u20134216. https:\/\/doi.org\/10.1182\/blood-2004-12-4785","journal-title":"Blood"},{"key":"4_CR91","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1016\/j.tim.2016.12.004","volume":"25","author":"M Naumann","year":"2017","unstructured":"Naumann M, Sokolova O, Tegtmeyer N, Backert S (2017) Helicobacter pylori: a paradigm pathogen for subverting host cell signal transmission. Trends Microbiol 25:316\u2013328. https:\/\/doi.org\/10.1016\/j.tim.2016.12.004","journal-title":"Trends Microbiol"},{"key":"4_CR92","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/ncomms6908","volume":"6","author":"Z Nie","year":"2015","unstructured":"Nie Z, Du MQ, McAllister-Lucas LM et al (2015) Conversion of the LIMA1 tumour suppressor into an oncogenic LMO-like protein by API2-MALT1 in MALT lymphoma. Nat Commun 6:1\u201313. https:\/\/doi.org\/10.1038\/ncomms6908","journal-title":"Nat Commun"},{"key":"4_CR93","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1111\/j.1440-1746.2008.05553.x","volume":"23","author":"JL O\u2019Rourke","year":"2008","unstructured":"O\u2019Rourke JL (2008) Gene expression profiling in Helicobacter-induced MALT lymphoma with reference to antigen drive and protective immunization. J Gastroenterol Hepatol 23:151\u2013156. https:\/\/doi.org\/10.1111\/j.1440-1746.2008.05553.x","journal-title":"J Gastroenterol Hepatol"},{"key":"4_CR94","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1093\/jrr\/rrw044","volume":"58","author":"Y Ohkubo","year":"2017","unstructured":"Ohkubo Y, Saito Y, Ushijima H et al (2017) Radiotherapy for localized gastric mucosa-associated lymphoid tissue lymphoma: Long-term outcomes over 10 years. J Radiat Res 58:537\u2013542. https:\/\/doi.org\/10.1093\/jrr\/rrw044","journal-title":"J Radiat Res"},{"key":"4_CR95","doi-asserted-by":"publisher","first-page":"7162","DOI":"10.4049\/jimmunol.175.11.7162","volume":"175","author":"T Ohmae","year":"2005","unstructured":"Ohmae T, Hirata Y, Maeda S et al (2005) Helicobacter pylori activates NF-kappaB via the alternative pathway in B lymphocytes. J Immunol 175:7162\u20137169. https:\/\/doi.org\/10.4049\/jimmunol.175.11.7162","journal-title":"J Immunol"},{"key":"4_CR96","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1111\/j.1365-2141.2008.07284.x","volume":"143","author":"G Packham","year":"2008","unstructured":"Packham G (2008) The role of NF-\u03baB in lymphoid malignancies. Br J Haematol 143:3\u201315. https:\/\/doi.org\/10.1111\/j.1365-2141.2008.07284.x","journal-title":"Br J Haematol"},{"key":"4_CR97","doi-asserted-by":"publisher","first-page":"1267","DOI":"10.1056\/NEJM199405053301803","volume":"330","author":"J Parsonnet","year":"1994","unstructured":"Parsonnet J, Hansen S, Rodriguez L et al (1994) Helicobacter pylori infection and gastric lymphoma. N Engl J Med 330:1267\u20131271. https:\/\/doi.org\/10.1056\/NEJM199405053301803","journal-title":"N Engl J Med"},{"key":"4_CR98","doi-asserted-by":"publisher","unstructured":"Petrakis G, Kostopoulos I, Venizelos I et al (2017) Expression of the activation markers Blimp1, Foxp1 and pStat3 in extranodal diffuse large B-cell lymphomas. Histol Histopathol 32:825\u2013834. https:\/\/doi.org\/10.14670\/HH-11-852","DOI":"10.14670\/HH-11-852"},{"key":"4_CR99","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1146\/annurev.immunol.23.021704.115728","volume":"23","author":"S Pillai","year":"2005","unstructured":"Pillai S, Cariappa A, Moran ST (2005) Marginal zone B cells. Annu Rev Immunol 23:161\u2013196. https:\/\/doi.org\/10.1146\/annurev.immunol.23.021704.115728","journal-title":"Annu Rev Immunol"},{"key":"4_CR100","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1016\/S1097-2765(02)00697-4","volume":"10","author":"JL Pomerantz","year":"2002","unstructured":"Pomerantz JL, Baltimore D (2002) Two pathways to NF-kappa B. Mol Cell 10:693\u2013695","journal-title":"Mol Cell"},{"key":"4_CR101","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1186\/1478-811X-11-77","volume":"11","author":"G Posselt","year":"2013","unstructured":"Posselt G, Backert S, Wessler S (2013) The functional interplay of Helicobacter pylori factors with gastric epithelial cells induces a multi-step process in pathogenesis. Cell Commun Signal 11:77. https:\/\/doi.org\/10.1186\/1478-811X-11-77","journal-title":"Cell Commun Signal"},{"key":"4_CR102","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1016\/j.molcel.2013.08.032","volume":"51","author":"Q Qiao","year":"2013","unstructured":"Qiao Q, Yang C, Zheng C et al (2013) Structural architecture of the CARMA1\/Bcl10\/MALT1 signalosome: nucleation-induced filamentous assembly. Mol Cell 51:766\u2013779. https:\/\/doi.org\/10.1016\/j.molcel.2013.08.032","journal-title":"Mol Cell"},{"key":"4_CR103","doi-asserted-by":"publisher","first-page":"1628","DOI":"10.1016\/0016-5085(92)91723-H","volume":"102","author":"T Radaszkiewicz","year":"1992","unstructured":"Radaszkiewicz T, Dragosics B, Bauer P (1992) Gastrointestinal malignant lymphomas of the mucosa-associated lymphoid tissue: factors relevant to prognosis. Gastroenterology 102:1628\u20131638. https:\/\/doi.org\/10.1016\/0016-5085(92)91723-H","journal-title":"Gastroenterology"},{"key":"4_CR104","doi-asserted-by":"publisher","first-page":"3349","DOI":"10.1158\/1078-0432.CCR-04-2282","volume":"11","author":"M Raderer","year":"2005","unstructured":"Raderer M, Streubel B, Woehrer S et al (2005) High relapse rate in patients with MALT lymphoma warrants lifelong follow-up. Clin Cancer Res 11:3349\u20133352. https:\/\/doi.org\/10.1158\/1078-0432.CCR-04-2282","journal-title":"Clin Cancer Res"},{"key":"4_CR105","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1007\/s00277-014-2298-3","volume":"94","author":"M Raderer","year":"2015","unstructured":"Raderer M, W\u00f6hrer S, Kiesewetter B et al (2015) Antibiotic treatment as sole management of Helicobacter pylori-negative gastric MALT lymphoma: a single center experience with prolonged follow-up. Ann Hematol 94:969\u2013973. https:\/\/doi.org\/10.1007\/s00277-014-2298-3","journal-title":"Ann Hematol"},{"key":"4_CR106","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1038\/nri1944","volume":"6","author":"DJ Rawlings","year":"2006","unstructured":"Rawlings DJ, Sommer K, Moreno-Garc\u00eda ME (2006) The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes. Nat Rev Immunol 6:799\u2013812. https:\/\/doi.org\/10.1038\/nri1944","journal-title":"Nat Rev Immunol"},{"key":"4_CR107","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1038\/ni1568","volume":"9","author":"F Rebeaud","year":"2008","unstructured":"Rebeaud F, Hailfinger S, Posevitz-Fejfar A et al (2008) The proteolytic activity of the paracaspase MALT1 is key in T cell activation. Nat Immunol 9:272\u2013281. https:\/\/doi.org\/10.1038\/ni1568","journal-title":"Nat Immunol"},{"key":"4_CR108","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1016\/S0002-9440(10)64988-7","volume":"156","author":"ED Remstein","year":"2000","unstructured":"Remstein ED, James CD, Kurtine PJ (2000) Incidence and subtype specificity of API2-MALT1 fusion translocations in extranodal, nodal, and splenic marginal zone lymphomas. Am J Pathol 156:1183\u20131188. https:\/\/doi.org\/10.1016\/S0002-9440(10)64988-7","journal-title":"Am J Pathol"},{"key":"4_CR109","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1038\/sj.leu.2403185","volume":"18","author":"ED Remstein","year":"2004","unstructured":"Remstein ED, Kurtin PJ, Einerson RR et al (2004) Primary pulmonary MALT lymphomas show frequent and heterogeneous cytogenetic abnormalities, including aneuploidy and translocations involving API2 and MALT1 and IGH and MALT1. Leukemia 18:156\u2013160. https:\/\/doi.org\/10.1038\/sj.leu.2403185","journal-title":"Leukemia"},{"key":"4_CR110","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1111\/j.1365-2141.2008.07237.x","volume":"142","author":"A Roehle","year":"2008","unstructured":"Roehle A, Hoefig KP, Repsilber D et al (2008) MicroRNA signatures characterize diffuse large B-cell lymphomas and follicular lymphomas. Br J Haematol 142:732\u2013744. https:\/\/doi.org\/10.1111\/j.1365-2141.2008.07237.x","journal-title":"Br J Haematol"},{"key":"4_CR111","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/S0046-8177(00)80233-6","volume":"31","author":"E Roggero","year":"2000","unstructured":"Roggero E, Zucca E, Mainetti C, Bertoni F (2000) Eradication of Borrelia burgdorferi infection in primary marginal zone B-cell lymphoma of the skin. Hum Pathol 31:263\u2013268","journal-title":"Hum Pathol"},{"key":"4_CR112","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1126\/science.1198946","volume":"331","author":"S Rosebeck","year":"2011","unstructured":"Rosebeck S, Madden L, Jin X et al (2011a) Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation. Science 331:468\u2013472. https:\/\/doi.org\/10.1126\/science.1198946","journal-title":"Science"},{"key":"4_CR113","doi-asserted-by":"publisher","first-page":"2485","DOI":"10.4161\/cc.10.15.16923","volume":"10","author":"S Rosebeck","year":"2011","unstructured":"Rosebeck S, Rehman AO, Lucas PC, McAllister-Lucas LM (2011b) From MALT lymphoma to the CBM signalosome: three decades of discovery. Cell Cycle 10:2485\u20132496. https:\/\/doi.org\/10.4161\/cc.10.15.16923","journal-title":"Cell Cycle"},{"key":"4_CR114","doi-asserted-by":"publisher","first-page":"6914","DOI":"10.1093\/emboj\/16.23.6914","volume":"16","author":"N Roy","year":"1997","unstructured":"Roy N, Deveraux QL, Takahashi R et al (1997) The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J 16:6914\u20136925. https:\/\/doi.org\/10.1093\/emboj\/16.23.6914","journal-title":"EMBO J"},{"key":"4_CR115","doi-asserted-by":"publisher","unstructured":"Ruefli-Brasse AA (2003) Regulation of NF-B-dependent lymphocyte activation and development by paracaspase. Science (80-) 302:1581\u20131584. https:\/\/doi.org\/10.1126\/science.1090769","DOI":"10.1126\/science.1090769"},{"key":"4_CR116","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/S0092-8674(01)00189-1","volume":"104","author":"J Ruland","year":"2001","unstructured":"Ruland J, Duncan GS, Elia A et al (2001) Bcl10 is a positive regulator of antigen receptor-induced activation of NF-\u03baB and neural tube closure. Cell 104:33\u201342. https:\/\/doi.org\/10.1016\/S0092-8674(01)00189-1","journal-title":"Cell"},{"key":"4_CR117","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1016\/S1074-7613(03)00293-0","volume":"19","author":"J Ruland","year":"2003","unstructured":"Ruland J, Duncan GS, Wakeham A, Mak TW (2003) Differential requirement for Malt1 in T and B cell antigen receptor signaling. Immunity 19:749\u2013758. https:\/\/doi.org\/10.1016\/S1074-7613(03)00293-0","journal-title":"Immunity"},{"key":"4_CR118","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.radonc.2015.08.029","volume":"117","author":"A Ruskon\u00e9-Fourmestraux","year":"2015","unstructured":"Ruskon\u00e9-Fourmestraux A, Matysiak-Budnik T, Fabiani B et al (2015) Exclusive moderate-dose radiotherapy in gastric marginal zone B-cell MALT lymphoma: results of a prospective study with a long term follow-up. Radiother Oncol 117:178\u2013182. https:\/\/doi.org\/10.1016\/j.radonc.2015.08.029","journal-title":"Radiother Oncol"},{"key":"4_CR119","doi-asserted-by":"publisher","first-page":"2490","DOI":"10.1200\/JCO.2006.05.6150","volume":"24","author":"X Sagaert","year":"2006","unstructured":"Sagaert X, De Paepe P, Libbrecht L et al (2006a) Forkhead box protein P1 expression in mucosa-associated lymphoid tissue lymphomas predicts poor prognosis and transformation to diffuse large B-cell lymphoma. J Clin Oncol 24:2490\u20132497. https:\/\/doi.org\/10.1200\/JCO.2006.05.6150","journal-title":"J Clin Oncol"},{"key":"4_CR120","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/modpathol.3800523","volume":"19","author":"X Sagaert","year":"2006","unstructured":"Sagaert X, Laurent M, Baens M et al (2006b) MALT1 and BCL10 aberrations in MALT lymphomas and their effect on the expression of BCL10 in the tumour cells. Mod Pathol 19:225\u2013232. https:\/\/doi.org\/10.1038\/modpathol.3800523","journal-title":"Mod Pathol"},{"key":"4_CR121","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1038\/modpathol.2009.182","volume":"23","author":"X Sagaert","year":"2010","unstructured":"Sagaert X, Tousseyn T, Vanhentenrijk V et al (2010a) Comparative expressed sequence hybridization studies of t(11;18)(q21;q21)-positive and-negative gastric MALT lymphomas reveal both unique and overlapping gene programs. Mod Pathol 23:458\u2013469. https:\/\/doi.org\/10.1038\/modpathol.2009.182","journal-title":"Mod Pathol"},{"key":"4_CR122","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1038\/nrgastro.2010.58","volume":"7","author":"X Sagaert","year":"2010","unstructured":"Sagaert X, Van Cutsem E, De Hertogh G et al (2010b) Gastric MALT lymphoma: a model of chronic inflammation-induced tumor development. Nat Rev Gastroenterol Hepatol 7:336\u2013346. https:\/\/doi.org\/10.1038\/nrgastro.2010.58","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"4_CR123","doi-asserted-by":"publisher","first-page":"e47396","DOI":"10.1371\/journal.pone.0047396","volume":"7","author":"Y Saito","year":"2012","unstructured":"Saito Y, Suzuki H, Tsugawa H et al (2012) Overexpression of miR-142-5p and miR-155 in gastric mucosa-associated lymphoid tissue (MALT) lymphoma resistant to Helicobacter pylori eradication. PLoS ONE 7:e47396. https:\/\/doi.org\/10.1371\/journal.pone.0047396","journal-title":"PLoS ONE"},{"key":"4_CR124","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1007\/s12308-017-0302-2","volume":"10","author":"MI Schreuder","year":"2017","unstructured":"Schreuder MI, van den Brand M, Hebeda KM et al (2017) Novel developments in the pathogenesis and diagnosis of extranodal marginal zone lymphoma. J Hematop 10:91\u2013107. https:\/\/doi.org\/10.1007\/s12308-017-0302-2","journal-title":"J Hematop"},{"key":"4_CR125","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/0092-8674(86)90346-6","volume":"46","author":"R Sen","year":"1986","unstructured":"Sen R, Baltimore D (1986) Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 46:705\u2013716","journal-title":"Cell"},{"key":"4_CR126","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1038\/nri1629","volume":"5","author":"U Siebenlist","year":"2005","unstructured":"Siebenlist U, Brown K, Claudio E (2005) Control of lymphocyte development by nuclear factor-\u03baB. Nat Rev Immunol 5:435\u2013445. https:\/\/doi.org\/10.1038\/nri1629","journal-title":"Nat Rev Immunol"},{"key":"4_CR127","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1038\/modpathol.2008.194","volume":"22","author":"DH Sinn","year":"2009","unstructured":"Sinn DH, Kim YH, Lee EJ et al (2009) Methylation and API2\/MALT1 fusion in colorectal extranodal marginal zone lymphoma. Mod Pathol 22:314\u2013320. https:\/\/doi.org\/10.1038\/modpathol.2008.194","journal-title":"Mod Pathol"},{"key":"4_CR128","doi-asserted-by":"publisher","first-page":"1742","DOI":"10.1038\/emboj.2011.85","volume":"30","author":"J Staal","year":"2011","unstructured":"Staal J, Driege Y, Bekaert T et al (2011) T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1. EMBO J 30:1742\u20131752. https:\/\/doi.org\/10.1038\/emboj.2011.85","journal-title":"EMBO J"},{"key":"4_CR129","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1182\/blood.V99.1.3","volume":"99","author":"P Starostik","year":"2002","unstructured":"Starostik P, Patzner J, Greiner A et al (2002) Gastric marginal zone B-cell lymphomas of MALT type develop along 2 distinct pathogenetic pathways. Blood 99:3\u20139. https:\/\/doi.org\/10.1182\/blood.V99.1.3","journal-title":"Blood"},{"key":"4_CR130","doi-asserted-by":"publisher","first-page":"1086","DOI":"10.1093\/annonc\/mdn760","volume":"20","author":"A Stathis","year":"2009","unstructured":"Stathis A, Chini C, Bertoni F et al (2009) Long-term outcome following Helicobacter pylori eradication in a retrospective study of 105 patients with localized gastric marginal zone B-cell lymphoma of MALT type. Ann Oncol 20:1086\u20131093. https:\/\/doi.org\/10.1093\/annonc\/mdn760","journal-title":"Ann Oncol"},{"key":"4_CR131","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1182\/blood-2008-12-195453","volume":"114","author":"A Stefanovic","year":"2009","unstructured":"Stefanovic A, Lossos IS (2009) Extranodal marginal zone lymphoma of the ocular adnexa. Blood 114:501\u2013510. https:\/\/doi.org\/10.1182\/blood-2008-12-195453","journal-title":"Blood"},{"key":"4_CR132","doi-asserted-by":"publisher","first-page":"2335","DOI":"10.1182\/blood-2002-09-2963","volume":"101","author":"B Streubel","year":"2003","unstructured":"Streubel B, Lamprecht A, Dierlamm J et al (2003) T(14;18)(q32;q21) involving IGH and MALT1 is a frequent chromosomal aberration in MALT lymphoma. Blood 101:2335\u20132339. https:\/\/doi.org\/10.1182\/blood-2002-09-2963","journal-title":"Blood"},{"key":"4_CR133","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1038\/sj.leu.2403644","volume":"19","author":"B Streubel","year":"2005","unstructured":"Streubel B, Vinatzer U, Lamprecht A et al (2005) T(3;14)(p14.1;q32) involving IGH and FOXP1 is a novel recurrent chromosomal aberration in MALT lymphoma. Leukemia 19:652\u2013658. https:\/\/doi.org\/10.1038\/sj.leu.2403644","journal-title":"Leukemia"},{"key":"4_CR134","doi-asserted-by":"publisher","first-page":"1884","DOI":"10.1053\/gast.2001.25305","volume":"120","author":"T Sugiyama","year":"2001","unstructured":"Sugiyama T, Asaka M, Nakamura T et al (2001) API2-MALT1 chimeric transcript is a predictive marker for the responsiveness of H. pylori eradication treatment in low-grade gastric MALT lymphoma [1] (multiple letters). Gastroenterology 120:1884\u20131885. https:\/\/doi.org\/10.1053\/gast.2001.25305","journal-title":"Gastroenterology"},{"key":"4_CR135","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1016\/S1097-2765(04)00236-9","volume":"14","author":"L Sun","year":"2004","unstructured":"Sun L, Deng L, Ea CK et al (2004) The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes. Mol Cell 14:289\u2013301. https:\/\/doi.org\/10.1016\/S1097-2765(04)00236-9","journal-title":"Mol Cell"},{"key":"4_CR136","unstructured":"Swerdlow SH, Campo E, Harris NL et al (2008) WHO classification of tumours of haematopoietic and lymphoid tissues, Revised 4th edn, Revised 4t. World Health Organization"},{"key":"4_CR137","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1111\/mmi.13707","volume":"105","author":"N Tegtmeyer","year":"2017","unstructured":"Tegtmeyer N, Neddermann M, Asche CI, Backert S (2017) Subversion of host kinases: a key network in cellular signaling hijacked by Helicobacter pylori CagA. Mol Microbiol 105:358\u2013372. https:\/\/doi.org\/10.1111\/mmi.13707","journal-title":"Mol Microbiol"},{"key":"4_CR138","doi-asserted-by":"publisher","first-page":"1624","DOI":"10.1200\/JCO.1997.15.4.1624","volume":"15","author":"C Thieblemont","year":"1997","unstructured":"Thieblemont C, Bastion Y, Berger F et al (1997) Mucosa-associated lymphoid tissue gastrointestinal and nongastrointestinal lymphoma behavior: analysis of 108 patients. J Clin Oncol 15:1624\u20131630. https:\/\/doi.org\/10.1200\/JCO.1997.15.4.1624","journal-title":"J Clin Oncol"},{"key":"4_CR139","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1182\/blood.V95.3.802.003k19_802_806","volume":"95","author":"C Thieblemont","year":"2000","unstructured":"Thieblemont C, Berger F, Dumontet C et al (2000) Mucosa-associated lymphoid tissue lymphoma is a disseminated disease in one third of 158 patients analyzed. Blood 95:802\u2013806","journal-title":"Blood"},{"key":"4_CR140","doi-asserted-by":"publisher","first-page":"1409","DOI":"10.1182\/blood-2017-03-771915","volume":"130","author":"C Thieblemont","year":"2017","unstructured":"Thieblemont C, Cascione L, Conconi A et al (2017) A MALT lymphoma prognostic index. Blood 130:1409\u20131417. https:\/\/doi.org\/10.1182\/blood-2017-03-771915","journal-title":"Blood"},{"key":"4_CR141","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1210\/jcem.87.1.8156","volume":"87","author":"C Thieblemont","year":"2002","unstructured":"Thieblemont C, Mayer A, Dumontet C et al (2002) Primary thyroid lymphoma is a heterogeneous disease. J Clin Endocrinol Metab 87:105\u2013111. https:\/\/doi.org\/10.1210\/jcem.87.1.8156","journal-title":"J Clin Endocrinol Metab"},{"key":"4_CR142","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1038\/nri1352","volume":"4","author":"M Thome","year":"2004","unstructured":"Thome M (2004) CARMA1, BCL-10 and MALT1 in lymphocyte development and activation. Nat Rev Immunol 4:348\u2013359. https:\/\/doi.org\/10.1038\/nri1352","journal-title":"Nat Rev Immunol"},{"key":"4_CR143","doi-asserted-by":"publisher","unstructured":"Thome M, Charton JE, Pelzer C, Hailfinger S (2010) Antigen receptor signaling to NF-kappaB via CARMA1, BCL10, and MALT1. Cold Spring Harb Perspect Biol 2. https:\/\/doi.org\/10.1101\/cshperspect.a003004","DOI":"10.1101\/cshperspect.a003004"},{"key":"4_CR144","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1007\/s00428-012-1215-1","volume":"460","author":"C Thorns","year":"2012","unstructured":"Thorns C, Kuba J, Bernard V et al (2012) Deregulation of a distinct set of microRNAs is associated with transformation of gastritis into MALT lymphoma. Virchows Arch 460:371\u2013377. https:\/\/doi.org\/10.1007\/s00428-012-1215-1","journal-title":"Virchows Arch"},{"key":"4_CR145","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1111\/j.1349-7006.2009.01128.x","volume":"100","author":"S Toracchio","year":"2009","unstructured":"Toracchio S, Ota H, de Jong D et al (2009) Translocation t(11;18)(q21;q21) in gastric B-cell lymphomas. Cancer Sci 100:881\u2013887. https:\/\/doi.org\/10.1111\/j.1349-7006.2009.01128.x","journal-title":"Cancer Sci"},{"key":"4_CR146","doi-asserted-by":"publisher","first-page":"738","DOI":"10.3324\/haematol.2008.001537","volume":"94","author":"M Troch","year":"2009","unstructured":"Troch M, Jonak C, M\u00fcllauer L et al (2009) A phase II study of bortezomib in patients with MALT lymphoma. Haematologica 94:738\u2013742. https:\/\/doi.org\/10.3324\/haematol.2008.001537","journal-title":"Haematologica"},{"key":"4_CR147","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1016\/j.jaci.2014.06.015","volume":"134","author":"SE Turvey","year":"2014","unstructured":"Turvey SE, Durandy A, Fischer A et al (2014) The CARD11-BCL10-MALT1 (CBM) signalosome complex: stepping into the limelight of human primary immunodeficiency. J Allergy Clin Immunol 134:276\u2013284. https:\/\/doi.org\/10.1016\/j.jaci.2014.06.015","journal-title":"J Allergy Clin Immunol"},{"key":"4_CR148","doi-asserted-by":"publisher","first-page":"2671","DOI":"10.1084\/jem.20091802","volume":"206","author":"MW Tusche","year":"2009","unstructured":"Tusche MW, Ward LA, Vu F et al (2009) Differential requirement of MALT1 for BAFF-induced outcomes in B cell subsets. J Exp Med 206:2671\u20132683. https:\/\/doi.org\/10.1084\/jem.20091802","journal-title":"J Exp Med"},{"key":"4_CR149","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1016\/S1097-2765(00)00094-0","volume":"6","author":"AG Uren","year":"2000","unstructured":"Uren AG, O\u2019Rourke K, Aravind L et al (2000) Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma. Mol Cell 6:961\u2013967. https:\/\/doi.org\/10.1016\/S1097-2765(00)00094-0","journal-title":"Mol Cell"},{"key":"4_CR150","doi-asserted-by":"publisher","first-page":"3431","DOI":"10.1182\/blood-2014-01-553412","volume":"124","author":"M Keimpema van","year":"2014","unstructured":"van Keimpema M, Gruneberg LJ, Mokry M et al (2014) FOXP1 directly represses transcription of proapoptotic genes and cooperates with NF-B to promote survival of human B cells. Blood 124:3431\u20133440. https:\/\/doi.org\/10.1182\/blood-2014-01-553412","journal-title":"Blood"},{"key":"4_CR151","doi-asserted-by":"publisher","first-page":"2098","DOI":"10.1182\/blood-2015-02-626176","volume":"126","author":"M Keimpema van","year":"2015","unstructured":"van Keimpema M, Gr\u00fcneberg LJ, Mokry M et al (2015) The forkhead transcription factor FOXP1 represses human plasma cell differentiation. Blood 126:2098\u20132109. https:\/\/doi.org\/10.1182\/blood-2015-02-626176","journal-title":"Blood"},{"key":"4_CR152","doi-asserted-by":"publisher","first-page":"6426","DOI":"10.1158\/1078-0432.CCR-08-0702","volume":"14","author":"U Vinatzer","year":"2008","unstructured":"Vinatzer U, Gollinger M, M\u00fcllauer L et al (2008) Mucosa-associated lymphoid tissue lymphoma: novel translocations including rearrangements of ODZ2, JMJD2C, and CNN3. Clin Cancer Res 14:6426\u20136431. https:\/\/doi.org\/10.1158\/1078-0432.CCR-08-0702","journal-title":"Clin Cancer Res"},{"issue":"1","key":"4_CR153","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1046\/j.1365-2249.2004.02338.x","volume":"135","author":"K Watanabe","year":"2004","unstructured":"Watanabe K, Murakami K, Sato R et al (2004) CTLA-4 blockade inhibits induction of Helicobacter pylori-associated. Clin Exp Immunol 135(1):29\u201334. https:\/\/doi.org\/10.1046\/j.1365-2249.2004.02338.x","journal-title":"Clin Exp Immunol"},{"key":"4_CR154","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/S0092-8674(00)80957-5","volume":"96","author":"TG Willis","year":"1999","unstructured":"Willis TG, Jadayel DM, Du MQ et al (1999) Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types. Cell 96:35\u201345. https:\/\/doi.org\/10.1016\/S0092-8674(00)80957-5","journal-title":"Cell"},{"key":"4_CR155","doi-asserted-by":"publisher","first-page":"1299","DOI":"10.1038\/sj.leu.2403813","volume":"19","author":"I Wlodarska","year":"2005","unstructured":"Wlodarska I, Veyt E, De Paepe P et al (2005) FOXP1, a gene highly expressed in a subset of diffuse large B-cell lymphoma, is recurrently targeted by genomic aberrations. Leukemia 19:1299\u20131305. https:\/\/doi.org\/10.1038\/sj.leu.2403813","journal-title":"Leukemia"},{"key":"4_CR156","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1016\/0140-6736(91)92035-Z","volume":"338","author":"AC Wotherspoon","year":"1991","unstructured":"Wotherspoon AC, Ortiz-Hidalgo C, Falzon MR, Isaacson PG (1991) Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma. Lancet (London, England) 338:1175\u20131176","journal-title":"Lancet (London, England)"},{"key":"4_CR157","doi-asserted-by":"publisher","first-page":"8018","DOI":"10.1200\/JCO.2005.02.3903","volume":"23","author":"T W\u00fcndisch","year":"2005","unstructured":"W\u00fcndisch T, Thiede C, Morgner A et al (2005) Long-term follow-up of gastric MALT lymphoma after Helicobacter pylori eradication. J Clin Oncol 23:8018\u20138024. https:\/\/doi.org\/10.1200\/JCO.2005.02.3903","journal-title":"J Clin Oncol"},{"key":"4_CR158","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.cell.2007.07.021","volume":"131","author":"C Xiao","year":"2007","unstructured":"Xiao C, Calado DP, Galler G et al (2007) MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb. Cell 131:146\u2013159. https:\/\/doi.org\/10.1016\/j.cell.2007.07.021","journal-title":"Cell"},{"key":"4_CR159","doi-asserted-by":"publisher","first-page":"1147","DOI":"10.1016\/S0002-9440(10)64630-5","volume":"157","author":"H Ye","year":"2000","unstructured":"Ye H, Dogan A, Karran L et al (2000) BCL 10 expression in normal and neoplastic lymphoid tissue: nuclear localization in MALT lymphoma. Am J Pathol 157:1147\u20131154. https:\/\/doi.org\/10.1016\/S0002-9440(10)64630-5","journal-title":"Am J Pathol"},{"key":"4_CR160","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1002\/path.1715","volume":"205","author":"H Ye","year":"2005","unstructured":"Ye H, Gong L, Liu H et al (2005) MALT lymphoma with t(14;18)(q32;q21)\/IGH-MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression. J Pathol 205:293\u2013301. https:\/\/doi.org\/10.1002\/path.1715","journal-title":"J Pathol"},{"key":"4_CR161","doi-asserted-by":"publisher","first-page":"1012","DOI":"10.1182\/blood-2002-11-3502","volume":"102","author":"H Ye","year":"2003","unstructured":"Ye H, Liu H, Attygalle A et al (2003) Variable frequencies of t(11;18)(q21;q21) in MALT lymphomas of different sites: significant association with CagA strains of H pylori in gastric MALT lymphoma. Blood 102:1012\u20131018. https:\/\/doi.org\/10.1182\/blood-2002-11-3502","journal-title":"Blood"},{"key":"4_CR162","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.blre.2016.10.001","volume":"31","author":"L Yu","year":"2017","unstructured":"Yu L, Li L, Medeiros LJ, Young KH (2017) NF-\u03baB signaling pathway and its potential as a target for therapy in lymphoid neoplasms. Blood Rev 31:77\u201392. https:\/\/doi.org\/10.1016\/j.blre.2016.10.001","journal-title":"Blood Rev"},{"key":"4_CR163","doi-asserted-by":"publisher","first-page":"5185","DOI":"10.4049\/jimmunol.1102952","volume":"189","author":"M Yu","year":"2012","unstructured":"Yu M, Chen Y, He Y et al (2012) Critical role of B cell lymphoma 10 in BAFF-regulated NF-\u03baB activation and survival of anergic B cells. J Immunol 189:5185\u20135193. https:\/\/doi.org\/10.4049\/jimmunol.1102952","journal-title":"J Immunol"},{"key":"4_CR164","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1007\/s13277-011-0192-3","volume":"32","author":"L Zhai","year":"2011","unstructured":"Zhai L, Zhao Y, Ye S et al (2011) Expression of PIK3CA and FOXP1 in gastric and intestinal non-Hodgkin\u2019s lymphoma of mucosa-associated lymphoid tissue type. Tumor Biol 32:913\u2013920. https:\/\/doi.org\/10.1007\/s13277-011-0192-3","journal-title":"Tumor Biol"},{"key":"4_CR165","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.cell.2016.12.012","volume":"168","author":"Q Zhang","year":"2017","unstructured":"Zhang Q, Lenardo MJ, Baltimore D (2017) 30 years of NF-\u03baB: a blossoming of relevance to human pathobiology. Cell 168:37\u201357. https:\/\/doi.org\/10.1016\/j.cell.2016.12.012","journal-title":"Cell"},{"key":"4_CR166","doi-asserted-by":"publisher","first-page":"e1004621","DOI":"10.1371\/journal.ppat.1004621","volume":"11","author":"XS Zhang","year":"2015","unstructured":"Zhang XS, Tegtmeyer N, Traube L, Jindal S, Perez-Perez G, Sticht H, Backert S, Blaser MJ (2015) A specific A\/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interaction. PloS Pathog 11:e1004621. https:\/\/doi.org\/10.1371\/journal.ppat.1004621","journal-title":"PloS Pathog"},{"key":"4_CR167","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1016\/j.ccr.2005.04.012","volume":"7","author":"H Zhou","year":"2005","unstructured":"Zhou H, Du MQ, Dixit VM (2005) Constitutive NF-\u03baB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity. Cancer Cell 7:425\u2013431. https:\/\/doi.org\/10.1016\/j.ccr.2005.04.012","journal-title":"Cancer Cell"},{"key":"4_CR168","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1111\/j.1365-2141.2006.05969.x","volume":"133","author":"Y Zhou","year":"2006","unstructured":"Zhou Y, Ye H, Martin-Subero JI et al (2006) Distinct comparative genomic hybridisation profiles in gastric mucosa-associated lymphoid tissue lymphomas with and without t(11;18)(q21;q21). Br J Haematol 133:35\u201342. https:\/\/doi.org\/10.1111\/j.1365-2141.2006.05969.x","journal-title":"Br J Haematol"},{"key":"4_CR169","doi-asserted-by":"publisher","first-page":"2489","DOI":"10.1182\/blood-2002-04-1279.Supported","volume":"101","author":"E Zucca","year":"2003","unstructured":"Zucca E, Conconi A, Pedrinis E et al (2003) Nongastric marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue. Arbor Cienc Pensam Y Cult 101:2489\u20132495. https:\/\/doi.org\/10.1182\/blood-2002-04-1279.Supported","journal-title":"Arbor Cienc Pensam Y Cult"},{"key":"4_CR170","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1093\/annonc\/mdt343","volume":"24","author":"E Zucca","year":"2013","unstructured":"Zucca E, Copie-Bergman C, Ricardi U et al (2013) Gastric marginal zone lymphoma of MALT type: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 24:145\u2013148. https:\/\/doi.org\/10.1093\/annonc\/mdt343","journal-title":"Ann Oncol"},{"key":"4_CR171","first-page":"147","volume":"85","author":"E Zucca","year":"2000","unstructured":"Zucca E, Roggero E, Maggi-Solc\u00e0 N, Conconi A (2000) Prevalence of Helicobacter pylori and hepatitis C virus infections among non-Hodgkin\u2019s lymphoma patients in Southern Switzerland. Haematologica 85:147\u2013153","journal-title":"Haematologica"},{"key":"4_CR172","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.cgh.2009.07.017","volume":"8","author":"A Zullo","year":"2010","unstructured":"Zullo A, Hassan C, Cristofari F et al (2010) Effects of helicobacter pylori eradication on early stage gastric mucosa-associated lymphoid tissue lymphoma. Clin Gastroenterol Hepatol 8:105\u2013110. https:\/\/doi.org\/10.1016\/j.cgh.2009.07.017","journal-title":"Clin Gastroenterol Hepatol"}],"container-title":["Current Topics in Microbiology and Immunology","Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter pylori"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-030-15138-6_4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,18]],"date-time":"2022-09-18T14:12:41Z","timestamp":1663510361000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-030-15138-6_4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"ISBN":["9783030151379","9783030151386"],"references-count":172,"URL":"https:\/\/doi.org\/10.1007\/978-3-030-15138-6_4","relation":{},"ISSN":["0070-217X","2196-9965"],"issn-type":[{"value":"0070-217X","type":"print"},{"value":"2196-9965","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]},"assertion":[{"value":"24 May 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}