{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T06:47:40Z","timestamp":1726037260885},"publisher-location":"Cham","reference-count":118,"publisher":"Springer International Publishing","isbn-type":[{"type":"print","value":"9783030186159"},{"type":"electronic","value":"9783030186166"}],"license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019]]},"DOI":"10.1007\/978-3-030-18616-6_1","type":"book-chapter","created":{"date-parts":[[2019,7,11]],"date-time":"2019-07-11T21:02:41Z","timestamp":1562878961000},"page":"3-20","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Form and Function in the\u00a0Digenea"],"prefix":"10.1007","author":[{"given":"Alba","family":"Cort\u00e9s Carbonell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernard","family":"Fried","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,7,12]]},"reference":[{"key":"1_CR1","doi-asserted-by":"publisher","first-page":"e2949","DOI":"10.1371\/journal.pntd.0002949","volume":"8","author":"LF Andrade","year":"2014","unstructured":"Andrade LF, Mourao Mde M, Geraldo JA, Coelho FS, Silva LL, Neves RH, Volpini A, Machado-Silva JR, Araujo N, Nacif-Pimenta R, Caffrey CR, Oliveira G (2014) Regulation of Schistosoma mansoni development and reproduction by the mitogen-activated protein kinase signaling pathway. PLoS Negl Trop Dis 8:e2949","journal-title":"PLoS Negl Trop Dis"},{"key":"1_CR2","doi-asserted-by":"publisher","first-page":"615","DOI":"10.2478\/s11686-014-0281-8","volume":"59","author":"L Antonelli","year":"2014","unstructured":"Antonelli L, Quilichini Y, Foata J, Marchand B (2014) Topography and ultrastructure of the tegument of Aphallus tubarium (Rodolphi, 1819) Poche, 1926 (Digenea: Cryptogonimidae), intestinal parasite of the common Dentex dentex (Linnaeus 1758) from Valinco Gulf. Acta Parasitol 59:615\u2013624","journal-title":"Acta Parasitol"},{"key":"1_CR3","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.actatropica.2014.12.003","volume":"143","author":"P Anuracpreeda","year":"2015","unstructured":"Anuracpreeda P, Phutong S, Ngamniyom A, Panyarachun B, Sobhon P (2015) Surface topography and ultrastructural architecture of the tegument of adult Carmyerius spatiosus Brandes, 1898. Acta Trop 143:18\u201328","journal-title":"Acta Trop"},{"key":"1_CR4","doi-asserted-by":"publisher","first-page":"2757","DOI":"10.1007\/s00436-016-5024-3","volume":"115","author":"P Anuracpreeda","year":"2016","unstructured":"Anuracpreeda P, Chawengkirttikul R, Sobhon P (2016) Surface histology, topography, and ultrastructure of the tegument of adult Orthocoelium parvipapillatum (Stiles & Goldberger, 1910). Parasitol Res 115:2757\u20132769","journal-title":"Parasitol Res"},{"key":"1_CR5","doi-asserted-by":"publisher","first-page":"e744","DOI":"10.7717\/peerj.744","volume":"3","author":"AJ Bakhoum","year":"2015","unstructured":"Bakhoum AJ, Quilichini Y, Justine JL, Bray RA, Ba CT, Marchand B (2015) Ultrastructural study of sperm cells in Acanthocolpidae: the case of Stephanostomum murielae and Stephanostomoides tenuis (Digenea). Peer J 3:e744","journal-title":"Peer J"},{"key":"1_CR6","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/bs.apar.2017.04.001","volume":"98","author":"AJS Bakhoum","year":"2017","unstructured":"Bakhoum AJS, Miquel J, Ndiaye PI, Justine JL, Falchi A, Ba CT, Marchand B, Quilichini Y (2017) Advances in spermatological characters in the Digenea: review and proposal of spermatozoa models and their phylogenetic importance. Adv Parasitol 98:111\u2013165","journal-title":"Adv Parasitol"},{"key":"1_CR7","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1111\/j.1476-5381.1966.tb01845.x","volume":"26","author":"LR Barker","year":"1966","unstructured":"Barker LR, Bueding E, Timms AR (1966) The possible role of acetylcholine in Schistosoma mansoni. Br J Pharmacol Chemother 26:656\u2013665","journal-title":"Br J Pharmacol Chemother"},{"key":"1_CR8","doi-asserted-by":"publisher","first-page":"e1000769","DOI":"10.1371\/journal.ppat.1000769","volume":"6","author":"S Beckmann","year":"2010","unstructured":"Beckmann S, Buro C, Dissous C, Hirzmann J, Grevelding CG (2010a) The Syk kinase SmTK4 of Schistosoma mansoni is involved in the regulation of spermatogenesis and oogenesis. PLoS Pathog 6:e1000769","journal-title":"PLoS Pathog"},{"key":"1_CR9","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1017\/S0031182010000053","volume":"137","author":"S Beckmann","year":"2010","unstructured":"Beckmann S, Quack T, Burmeister C, Buro C, Long T, Dissous C, Grevelding CG (2010b) Schistosoma mansoni: signal transduction processes during the development of the reproductive organs. Parasitology 137:497\u2013520","journal-title":"Parasitology"},{"key":"1_CR10","doi-asserted-by":"publisher","first-page":"42325","DOI":"10.1074\/jbc.M110.210336","volume":"286","author":"S Beckmann","year":"2011","unstructured":"Beckmann S, Hahnel S, Cailliau K, Vanderstraete M, Browaeys E, Dissous C, Grevelding CG (2011) Characterization of the Src\/Abl hybrid kinase SmTK6 of Schistosoma mansoni. J Biol Chem 286:42325\u201342336","journal-title":"J Biol Chem"},{"key":"1_CR11","doi-asserted-by":"publisher","first-page":"e52519","DOI":"10.1371\/journal.pone.0052519","volume":"7","author":"S Beckmann","year":"2012","unstructured":"Beckmann S, Quack T, Dissous C, Cailliau K, Lang G, Grevelding CG (2012) Discovery of platyhelminth-specific alpha\/beta-integrin families and evidence for their role in reproduction in Schistosoma mansoni. PLoS One 7:e52519","journal-title":"PLoS One"},{"key":"1_CR12","first-page":"327","volume-title":"Principles of comparative anatomy of invertebrates","author":"WN Beklemishev","year":"1969","unstructured":"Beklemishev WN (1969) Origin and development of the excretory apparatus. In: Kabata Z (ed) Principles of comparative anatomy of invertebrates, vol 2. Oliver & Boyd, Edinburgh, pp 327\u2013352"},{"key":"1_CR13","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1016\/j.jprot.2014.02.012","volume":"105","author":"D Bernal","year":"2014","unstructured":"Bernal D, Trelis M, Montaner S, Cantalapiedra F, Galiano A, Hackenberg M, Marcilla A (2014) Surface analysis of Dicrocoelium dendriticum. The molecular characterization of exosomes reveals the presence of miRNAs. J Proteomics 105:232\u2013241","journal-title":"J Proteomics"},{"key":"1_CR14","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/B978-0-12-415915-0.00009-1","volume-title":"Human parasitology","author":"BJ Bogitsh","year":"2013","unstructured":"Bogitsh BJ, Carter CE, Oeltmann TN (2013) General characteristics of the Trematoda. In: Bogitsh BJ, Carter CE, Oeltmann TN (eds) Human parasitology, 4th edn. Academic Press, Waltham, pp 153\u2013178","edition":"4"},{"key":"1_CR15","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1002\/jmor.20700","volume":"278","author":"A Born-Torrijos","year":"2017","unstructured":"Born-Torrijos A, Holzer AS, Raga JA, van Beest GS, Yoneva A (2017) Description of embryonic development and ultrastructure in miracidia of Cardiocephaloides longicollis (Digenea, Strigeidae) in relation to active host finding strategy in a marine environment. J Morphol 278:1137\u20131148","journal-title":"J Morphol"},{"key":"1_CR16","doi-asserted-by":"publisher","first-page":"e1003448","DOI":"10.1371\/journal.ppat.1003448","volume":"9","author":"C Buro","year":"2013","unstructured":"Buro C, Oliveira KC, Lu Z, Leutner S, Beckmann S, Dissous C, Cailliau K, Verjovski-Almeida S, Grevelding CG (2013) Transcriptome analyses of inhibitor-treated schistosome females provide evidence for cooperating Src-kinase and TGFbeta receptor pathways controlling mitosis and eggshell formation. PLoS Pathog 9:e1003448","journal-title":"PLoS Pathog"},{"key":"1_CR17","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.exppara.2016.12.002","volume":"180","author":"C Buro","year":"2017","unstructured":"Buro C, Burmeister C, Quack T, Grevelding CG (2017) Identification and first characterization of SmEps8, a potential interaction partner of SmTK3 and SER transcribed in the gonads of Schistosoma mansoni. Exp Parasitol 180:55\u201363","journal-title":"Exp Parasitol"},{"key":"1_CR18","doi-asserted-by":"publisher","first-page":"e1004116","DOI":"10.1371\/journal.ppat.1004116","volume":"10","author":"VC Carneiro","year":"2014","unstructured":"Carneiro VC, de Abreu da Silva IC, Torres EJ, Caby S, Lancelot J, Vanderstraete M, Furdas SD, Jung M, Pierce RJ, Fantappie MR (2014) Epigenetic changes modulate schistosome egg formation and are a novel target for reducing transmission of schistosomiasis. PLoS Pathog 10:e1004116","journal-title":"PLoS Pathog"},{"key":"1_CR19","doi-asserted-by":"publisher","first-page":"1636","DOI":"10.1093\/infdis\/jiv291","volume":"212","author":"S Chaiyadet","year":"2015","unstructured":"Chaiyadet S, Sotillo J, Smout M, Cantacessi C, Jones MK, Johnson MS, Turnbull L, Whitchurch CB, Potriquet J, Laohaviroj M, Mulvenna J, Brindley PJ, Bethony JM, Laha T, Sripa B, Loukas A (2015) Carcinogenic liver fluke secretes extracellular vesicles that promote cholangiocytes to adopt a tumorigenic phenotype. J Infect Dis 212:1636\u20131645","journal-title":"J Infect Dis"},{"key":"1_CR20","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1016\/j.ijpddr.2016.06.001","volume":"6","author":"JD Chan","year":"2016","unstructured":"Chan JD, Acharya S, Day TA, Marchant JS (2016a) Pharmacological profiling an abundantly expressed schistosome serotonergic GPCR identifies nuciferine as a potent antagonist. Int J Parasitol Drugs Drug Resist 6:364\u2013370","journal-title":"Int J Parasitol Drugs Drug Resist"},{"key":"1_CR21","doi-asserted-by":"publisher","first-page":"e1005651","DOI":"10.1371\/journal.ppat.1005651","volume":"12","author":"JD Chan","year":"2016","unstructured":"Chan JD, McCorvy JD, Acharya S, Johns ME, Day TA, Roth BL, Marchant JS (2016b) A miniaturized screen of a Schistosoma mansoni serotonergic G protein-coupled receptor identifies novel classes of parasite-selective inhibitors. PLoS Pathog 12:e1005651","journal-title":"PLoS Pathog"},{"key":"1_CR22","doi-asserted-by":"publisher","first-page":"e12473","DOI":"10.7554\/eLife.12473","volume":"5","author":"JJ Collins III","year":"2016","unstructured":"Collins JJ III, Wendt GR, Iyer H, Newmark PA (2016) Stem cell progeny contribute to the schistosome host-parasite interface. Elife 5:e12473","journal-title":"Elife"},{"key":"1_CR23","doi-asserted-by":"publisher","first-page":"e0005773","DOI":"10.1371\/journal.pntd.0005773","volume":"11","author":"A Cort\u00e9s","year":"2017","unstructured":"Cort\u00e9s A, Sotillo J, Mu\u00f1oz-Antol\u00ed C, Molina-Dur\u00e1n J, Esteban JG, Toledo R (2017) Antibody trapping: a novel mechanism of parasite immune evasion by the trematode Echinostoma caproni. PLoS Negl Trop Dis 11:e0005773","journal-title":"PLoS Negl Trop Dis"},{"key":"1_CR24","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1186\/s13059-015-0632-2","volume":"16","author":"K Cwiklinski","year":"2015","unstructured":"Cwiklinski K, Dalton JP, Dufresne PJ, La Course J, Williams DJ, Hodgkinson J, Paterson S (2015a) The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution. Genome Biol 16:71","journal-title":"Genome Biol"},{"key":"1_CR25","doi-asserted-by":"publisher","first-page":"3258","DOI":"10.1074\/mcp.M115.053934","volume":"14","author":"K Cwiklinski","year":"2015","unstructured":"Cwiklinski K, de la Torre-Escudero E, Trelis M, Bernal D, Dufresne PJ, Brennan GP, O\u2019Neill S, Tort J, Paterson S, Marcilla A, Dalton JP, Robinson MW (2015b) The extracellular vesicles of the helminth pathogen, Fasciola hepatica: biogenesis pathways and cargo molecules involved in parasite pathogenesis. Mol Cell Proteomics 14:3258\u20133273","journal-title":"Mol Cell Proteomics"},{"key":"1_CR26","doi-asserted-by":"publisher","first-page":"e316","DOI":"10.7717\/peerj.316","volume":"2","author":"AA Da\u2019dara","year":"2014","unstructured":"Da\u2019dara AA, Bhardwaj R, Ali YB, Skelly PJ (2014) Schistosome tegumental ecto-apyrase (SmATPDase1) degrades exogenous pro-inflammatory and pro-thrombotic nucleotides. Peer J 2:e316","journal-title":"Peer J"},{"key":"1_CR27","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.ijpara.2015.12.007","volume":"46","author":"IC Silva de Abreu da","year":"2016","unstructured":"de Abreu da Silva IC, Carneiro VC, Vicentino AR, Aguilera EA, Mohana-Borges R, Thiengo S, Fernandez MA, Fantappie MR (2016) The distinct C-terminal acidic domains of HMGB proteins are functionally relevant in Schistosoma mansoni. Int J Parasitol 46:253\u2013262","journal-title":"Int J Parasitol"},{"key":"1_CR28","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1186\/s13071-017-2453-5","volume":"10","author":"H Ding","year":"2017","unstructured":"Ding H, Liu F, Zhu L, Wu F, Liu Q, He S, Shao W, Du Y, Ren C, Shen J, Liu M (2017) Tyrosine kinase 4 is involved in the reproduction of the platyhelminth parasite Schistosoma japonicum. Parasit Vectors 10:498","journal-title":"Parasit Vectors"},{"key":"1_CR29","doi-asserted-by":"publisher","first-page":"7104","DOI":"10.1523\/JNEUROSCI.0378-08.2008","volume":"28","author":"JS Dittman","year":"2008","unstructured":"Dittman JS, Kaplan JM (2008) Behavioral impact of neurotransmitter-activated G-protein-coupled receptors: muscarinic and GABAB receptors regulate Caenorhabditis elegans locomotion. J Neurosci 28:7104\u20137112","journal-title":"J Neurosci"},{"key":"1_CR30","doi-asserted-by":"publisher","first-page":"dmm033563","DOI":"10.1242\/dmm.033563","volume":"11","author":"N El-Sakkary","year":"2018","unstructured":"El-Sakkary N, Chen S, Arkin MR, Caffrey CR, Ribeiro P (2018) Octopamine signaling in the metazoan pathogen Schistosoma mansoni: localization, small-molecule screening and opportunities for drug development. Dis Model Mech 11:dmm033563. \n                    https:\/\/doi.org\/10.1242\/dmm.033563","journal-title":"Dis Model Mech"},{"key":"1_CR31","doi-asserted-by":"publisher","first-page":"1395","DOI":"10.1016\/j.ijpara.2010.04.006","volume":"40","author":"F El-Shehabi","year":"2010","unstructured":"El-Shehabi F, Ribeiro P (2010) Histamine signalling in Schistosoma mansoni: immunolocalisation and characterisation of a new histamine-responsive receptor (SmGPR-2). Int J Parasitol 40:1395\u20131406","journal-title":"Int J Parasitol"},{"key":"1_CR32","doi-asserted-by":"publisher","first-page":"e1523","DOI":"10.1371\/journal.pntd.0001523","volume":"6","author":"F El-Shehabi","year":"2012","unstructured":"El-Shehabi F, Taman A, Moali LS, El-Sakkary N, Ribeiro P (2012) A novel G protein-coupled receptor of Schistosoma mansoni (SmGPR-3) is activated by dopamine and is widely expressed in the nervous system. PLoS Negl Trop Dis 6:e1523","journal-title":"PLoS Negl Trop Dis"},{"key":"1_CR33","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1002\/(SICI)1096-9861(19960916)373:2<220::AID-CNE5>3.0.CO;2-5","volume":"373","author":"KS Eriksson","year":"1996","unstructured":"Eriksson KS, Johnston RN, Shaw C, Halton DW, Panula PA (1996) Widespread distribution of histamine in the nervous system of a trematode flatworm. J Comp Neurol 373:220\u2013227","journal-title":"J Comp Neurol"},{"key":"1_CR34","doi-asserted-by":"publisher","first-page":"2780","DOI":"10.1096\/fj.09-130757","volume":"23","author":"Z Faghiri","year":"2009","unstructured":"Faghiri Z, Skelly PJ (2009) The role of tegumental aquaporin from the human parasitic worm, Schistosoma mansoni, in osmoregulation and drug uptake. FASEB J 23:2780\u20132789","journal-title":"FASEB J"},{"key":"1_CR35","doi-asserted-by":"publisher","first-page":"753","DOI":"10.4155\/fmc.15.21","volume":"7","author":"LG Ferreira","year":"2015","unstructured":"Ferreira LG, Oliva G, Andricopulo AD (2015) Target-based molecular modeling strategies for schistosomiasis drug discovery. Future Med Chem 7:753\u2013764","journal-title":"Future Med Chem"},{"key":"1_CR36","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1007\/s00436-012-3162-9","volume":"112","author":"JJ Filippi","year":"2013","unstructured":"Filippi JJ, Quilichini Y, Marchand B (2013) Topography and ultrastructure of the tegument of Deropristis inflata Molin, 1859 (Digenea: Deropristidae), a parasite of the European eel Anguilla anguilla (Osteichthyes: Anguillidae). Parasitol Res 112:517\u2013528","journal-title":"Parasitol Res"},{"key":"1_CR37","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1017\/S003118200300427X","volume":"128","author":"HL Fletcher","year":"2004","unstructured":"Fletcher HL, Hoey EM, Orr N, Trudgett A, Fairweather I, Robinson MW (2004) The occurrence and significance of triploidy in the liver fluke, Fasciola hepatica. Parasitology 128:69\u201372","journal-title":"Parasitology"},{"key":"1_CR38","first-page":"1","volume-title":"Advances in trematode biology","author":"B Fried","year":"1997","unstructured":"Fried B (1997) An overview of the biology of trematodes. In: Fried B, Graczyk TK (eds) Advances in trematode biology. CRC, Boca Raton, pp 1\u201330"},{"key":"1_CR39","first-page":"141","volume-title":"Microscopic anatomy of invertebrates","author":"B Fried","year":"1991","unstructured":"Fried B, Haseeb MA (1991) Platyhelminthes, Aspidogastrea, Monogenea, and Digenea. In: Harrison FW, Bogitsh BJ (eds) Microscopic anatomy of invertebrates, vol 3. Wiley and Liss, New York, pp 141\u2013209"},{"key":"1_CR40","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.biochi.2014.11.013","volume":"108","author":"A Geadkaew","year":"2015","unstructured":"Geadkaew A, von Bulow J, Beitz E, Tesana S, Vichasri Grams S, Grams R (2015) Bi-functionality of Opisthorchis viverrini aquaporins. Biochimie 108:149\u2013159","journal-title":"Biochimie"},{"key":"1_CR41","doi-asserted-by":"publisher","first-page":"e1006147","DOI":"10.1371\/journal.ppat.1006147","volume":"13","author":"V Gelmedin","year":"2017","unstructured":"Gelmedin V, Morel M, Hahnel S, Cailliau K, Dissou SC, Grevelding CG (2017) Evidence for integrin - venus kinase receptor 1 alliance in the ovary of Schistosoma mansoni females controlling cell survival. PLoS Pathog 13:e1006147","journal-title":"PLoS Pathog"},{"key":"1_CR42","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1051\/parasite\/2016057","volume":"23","author":"S Greani","year":"2016","unstructured":"Greani S, Quilichini Y, Marchand B (2016) Ultrastructural study of vitellogenesis and oogenesis of Crepidostomum metoecus (Digenea, Allocreadiidae), intestinal parasite of Salmo trutta (Pisces, Teleostei). Parasite 23:47","journal-title":"Parasite"},{"key":"1_CR43","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1016\/j.parint.2013.02.006","volume":"62","author":"RM Greenberg","year":"2013","unstructured":"Greenberg RM (2013) ABC multidrug transporters in schistosomes and other parasitic flatworms. Parasitol Int 62:647\u2013653","journal-title":"Parasitol Int"},{"key":"1_CR44","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1007\/s40588-014-0007-6","volume":"1","author":"RM Greenberg","year":"2014","unstructured":"Greenberg RM (2014) Ion channels and drug transporters as targets for anthelmintics. Curr Clin Microbiol Rep 1:51\u201360","journal-title":"Curr Clin Microbiol Rep"},{"key":"1_CR45","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.molbiopara.2017.01.007","volume":"213","author":"S Hahnel","year":"2017","unstructured":"Hahnel S, Parker-Manuel R, Dissous C, Cailliau K, Grevelding CG (2017) First characterization of SmOPG1, a novel protein involved in gonad-associated processes in Schistosoma mansoni. Mol Biochem Parasitol 213:22\u201325","journal-title":"Mol Biochem Parasitol"},{"key":"1_CR46","doi-asserted-by":"publisher","first-page":"e1006718","DOI":"10.1371\/journal.ppat.1006718","volume":"14","author":"S Hahnel","year":"2018","unstructured":"Hahnel S, Wheeler N, Lu Z, Wangwiwatsin A, McVeigh P, Maule A, Berriman M, Day T, Ribeiro P, Grevelding CG (2018) Tissue-specific transcriptome analyses provide new insights into GPCR signalling in adult Schistosoma mansoni. PLoS Pathog 14:e1006718","journal-title":"PLoS Pathog"},{"key":"1_CR47","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/j.micron.2003.12.001","volume":"35","author":"DW Halton","year":"2004","unstructured":"Halton DW (2004) Microscopy and the helminth parasite. Micron 35:361\u2013390","journal-title":"Micron"},{"key":"1_CR48","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1139\/z03-221","volume":"82","author":"DW Halton","year":"2004","unstructured":"Halton DW, Maule AG (2004) Flatworm nerve-muscle: structural and functional analysis. Can J Zool 82:316\u2013333","journal-title":"Can J Zool"},{"key":"1_CR49","doi-asserted-by":"publisher","first-page":"5212","DOI":"10.1038\/s41598-017-05602-8","volume":"7","author":"Q Han","year":"2017","unstructured":"Han Q, Jia B, Hong Y, Cao X, Zhai Q, Lu K, Li H, Zhu C, Fu Z, Shi Y, Lin J (2017) Suppression of VAMP2 alters morphology of the tegument and affects glucose uptake, development and reproduction of Schistosoma japonicum. Sci Rep 7:5212","journal-title":"Sci Rep"},{"key":"1_CR50","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.vetpar.2016.03.011","volume":"221","author":"RE Hanna","year":"2016","unstructured":"Hanna RE, Moffett D, Forster FI, Trudgett AG, Brennan GP, Fairweather I (2016) Fasciola hepatica: a light and electron microscope study of the ovary and of the development of oocytes within eggs in the uterus provides an insight into reproductive strategy. Vet Parasitol 221:93\u2013103","journal-title":"Vet Parasitol"},{"key":"1_CR51","doi-asserted-by":"publisher","first-page":"10","DOI":"10.2307\/3226778","volume":"112","author":"LA Hertel","year":"1993","unstructured":"Hertel LA (1993) Excretion and osmoregulation in the flatworms. Trans Am Microsc Soc 112:10\u201317","journal-title":"Trans Am Microsc Soc"},{"key":"1_CR52","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1016\/0014-4894(84)90035-3","volume":"58","author":"SD Holmes","year":"1984","unstructured":"Holmes SD, Fairweather I (1984) Fasciola hepatica: the effects of neuropharmacological agents upon in vitro motility. Exp Parasitol 58:194\u2013208","journal-title":"Exp Parasitol"},{"key":"1_CR53","doi-asserted-by":"publisher","first-page":"e54732","DOI":"10.1371\/journal.pone.0054732","volume":"8","author":"Y Huang","year":"2013","unstructured":"Huang Y, Chen W, Wang X, Liu H, Chen Y, Guo L, Luo F, Sun J, Mao Q, Liang P, Xie Z, Zhou C, Tian Y, Lv X, Huang L, Zhou J, Hu Y, Li R, Zhang F, Lei H, Li W, Hu X, Liang C, Xu J, Li X, Yu X (2013) The carcinogenic liver fluke, Clonorchis sinensis: new assembly, reannotation and analysis of the genome and characterization of tissue transcriptomes. PLoS One 8:e54732","journal-title":"PLoS One"},{"key":"1_CR54","doi-asserted-by":"publisher","first-page":"35030","DOI":"10.1038\/srep35030","volume":"6","author":"Y Huang","year":"2016","unstructured":"Huang Y, Li W, Lu W, Xiong C, Yang Y, Yan H, Liu KC, Cao P (2016) Cloning and in vitro characterization of a Schistosoma japonicum aquaglyceroporin that functions in osmoregulation. Sci Rep 6:35030","journal-title":"Sci Rep"},{"key":"1_CR55","doi-asserted-by":"publisher","first-page":"e3265","DOI":"10.1371\/journal.pntd.0003265","volume":"8","author":"RS Kasinathan","year":"2014","unstructured":"Kasinathan RS, Sharma LK, Cunningham C, Webb TR, Greenberg RM (2014) Inhibition or knockdown of ABC transporters enhances susceptibility of adult and juvenile schistosomes to praziquantel. PLoS Negl Trop Dis 8:e3265","journal-title":"PLoS Negl Trop Dis"},{"issue":"sup1","key":"1_CR056","doi-asserted-by":"publisher","first-page":"S9","DOI":"10.1517\/17460441.2.S1.S9","volume":"2","author":"Jennifer Keiser","year":"2007","unstructured":"Keiser J, Utzinger J (2007) Advances in the discovery and development of trematocidal drugs. Expert Opin Drug Discov 2(sup1):S9\u2013S23","journal-title":"Expert Opinion on Drug Discovery"},{"key":"1_CR055","doi-asserted-by":"crossref","unstructured":"Kotze AC, Hunt PW, Skuce P, von Samson-Himmelstjerna G, Martin RJ, Sager H, Kr\u00fccken J, Hodgkinson J, Lespine A, Jex AR, Gilleard JS, Beech RN, Wolstenholme AJ, Demeler J, Robertson AP, Charvet CL, Neveu C, Kaminsky R, Rufener L, Alberich M, Menez C, Prichard RK (2014) Int J Parasitol Drugs Drug Resist 4:164\u2013184","DOI":"10.1016\/j.ijpddr.2014.07.007"},{"key":"1_CR56","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1016\/j.pt.2016.03.002","volume":"32","author":"JM Kelley","year":"2016","unstructured":"Kelley JM, Elliott TP, Beddoe T, Anderson G, Skuce P, Spithill TW (2016) Current threat of triclabendazole resistance in Fasciola hepatica. Trends Parasitol 32:458\u2013469","journal-title":"Trends Parasitol"},{"key":"1_CR57","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1186\/s12862-015-0468-0","volume":"15","author":"DY Krupenko","year":"2015","unstructured":"Krupenko DY, Dobrovolskij AA (2015) Somatic musculature in trematode hermaphroditic generation. BMC Evol Biol 15:189","journal-title":"BMC Evol Biol"},{"key":"1_CR58","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1016\/j.parint.2017.02.002","volume":"66","author":"D Krupenko","year":"2017","unstructured":"Krupenko D, Gonchar A (2017a) Musculature arrangement and locomotion in notocotylid cercariae (Digenea: Notocotylidae) from mud snail Ecrobia ventrosa (Montagu, 1803). Parasitol Int 66:262\u2013271","journal-title":"Parasitol Int"},{"key":"1_CR59","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1016\/j.parint.2017.06.008","volume":"66","author":"D Krupenko","year":"2017","unstructured":"Krupenko D, Gonchar A (2017b) Ventral concavity and musculature arrangement in notocotylid maritae (Digenea: Notocotylidae). Parasitol Int 66:660\u2013665","journal-title":"Parasitol Int"},{"key":"1_CR60","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1007\/s11010-008-9833-2","volume":"317","author":"S Kumkate","year":"2008","unstructured":"Kumkate S, Chunchob S, Janvilisri T (2008) Expression of ATP-binding cassette multidrug transporters in the giant liver fluke Fasciola gigantica and their possible involvement in the transport of bile salts and anthelmintics. Mol Cell Biochem 317:77\u201384","journal-title":"Mol Cell Biochem"},{"key":"1_CR61","doi-asserted-by":"publisher","first-page":"1653","DOI":"10.1111\/bph.12898","volume":"172","author":"CY Leow","year":"2015","unstructured":"Leow CY, Willis C, Hofmann A, Jones MK (2015) Structure-function analysis of apical membrane-associated molecules of the tegument of schistosome parasites of humans: prospects for identification of novel targets for parasite control. Br J Pharmacol 172:1653\u20131663","journal-title":"Br J Pharmacol"},{"key":"1_CR62","first-page":"190","volume":"49","author":"C Levron","year":"2004","unstructured":"Levron C, Ternengo S, Marchand B (2004) Spermiogenesis and sperm ultrastructure of Poracanthium furcatum (Digenea, Opecoelidae), a parasite of Mullus surmuletus (Pisces, Teleostei). Acta Parasitol 49:190\u2013200","journal-title":"Acta Parasitol"},{"key":"1_CR63","doi-asserted-by":"publisher","first-page":"e2337","DOI":"10.1371\/journal.pntd.0002337","volume":"7","author":"XH Li","year":"2013","unstructured":"Li XH, de Castro-Borges W, Parker-Manuel S, Vance GM, Demarco R, Neves LX, Evans GJ, Wilson RA (2013) The schistosome oesophageal gland: initiator of blood processing. PLoS Negl Trop Dis 7:e2337","journal-title":"PLoS Negl Trop Dis"},{"key":"1_CR64","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1186\/s13071-014-0565-8","volume":"7","author":"XH Li","year":"2014","unstructured":"Li XH, Stark M, Vance GM, Cao JP, Wilson RA (2014) The anterior esophageal region of Schistosoma japonicum is a secretory organ. Parasit Vectors 7:565","journal-title":"Parasit Vectors"},{"key":"1_CR65","doi-asserted-by":"publisher","first-page":"e0006235","DOI":"10.1371\/journal.pntd.0006235","volume":"12","author":"XH Li","year":"2018","unstructured":"Li XH, DeMarco R, Neves LX, James SR, Newling K, Ashton PD, Cao JP, Wilson RA, Castro-Borges W (2018) Microexon gene transcriptional profiles and evolution provide insights into blood processing by the Schistosoma japonicum esophagus. PLoS Negl Trop Dis 12:e0006235","journal-title":"PLoS Negl Trop Dis"},{"key":"1_CR66","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1017\/CBO9781139794749.020","volume-title":"Parasite diversity and diversification: evolutionary ecology meets phylogenetics","author":"DTJ Littlewood","year":"2015","unstructured":"Littlewood DTJ, Bray RA, Waeschenbach A (2015) Phylogenetic patterns of diversity in cestodes and trematodes. In: Morand S, Krasnov B, Littlewood DTJ (eds) Parasite diversity and diversification: evolutionary ecology meets phylogenetics. Cambridge University Press, Cambridge, pp 304\u2013319"},{"key":"1_CR67","doi-asserted-by":"publisher","first-page":"31150","DOI":"10.1038\/srep31150","volume":"6","author":"Z Lu","year":"2016","unstructured":"Lu Z, Sessler F, Holroyd N, Hahnel S, Quack T, Berriman M, Grevelding CG (2016) Schistosome sex matters: a deep view into gonad-specific and pairing-dependent transcriptomes reveals a complex gender interplay. Sci Rep 6:31150","journal-title":"Sci Rep"},{"key":"1_CR68","doi-asserted-by":"publisher","first-page":"e1004181","DOI":"10.1371\/journal.ppat.1004181","volume":"10","author":"K MacDonald","year":"2014","unstructured":"MacDonald K, Buxton S, Kimber MJ, Day TA, Robertson AP, Ribeiro P (2014) Functional characterization of a novel family of acetylcholine-gated chloride channels in Schistosoma mansoni. PLoS Pathog 10:e1004181","journal-title":"PLoS Pathog"},{"key":"1_CR69","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.molbiopara.2015.09.001","volume":"202","author":"K MacDonald","year":"2015","unstructured":"MacDonald K, Kimber MJ, Day TA, Ribeiro P (2015) A constitutively active G protein-coupled acetylcholine receptor regulates motility of larval Schistosoma mansoni. Mol Biochem Parasitol 202:29\u201337","journal-title":"Mol Biochem Parasitol"},{"key":"1_CR70","doi-asserted-by":"publisher","first-page":"e45974","DOI":"10.1371\/journal.pone.0045974","volume":"7","author":"A Marcilla","year":"2012","unstructured":"Marcilla A, Trelis M, Cort\u00e9s A, Sotillo J, Cantalapiedra F, M\u00ednguez MT, Valero ML, S\u00e1nchez del Pino MM, Mu\u00f1oz-Antol\u00ed C, Toledo R, Bernal D (2012) Extracellular vesicles from parasitic helminths contain specific excretory\/secretory proteins and are internalized in intestinal host cells. PLoS One 7:e45974","journal-title":"PLoS One"},{"key":"1_CR71","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/978-1-4419-6902-6_4","volume-title":"Neuropeptide systems as targets for parasite and pest control","author":"NJ Marks","year":"2010","unstructured":"Marks NJ, Maule AG (2010) Neuropeptides in helminths: occurrence and distribution. In: Geary TG, Maule AG (eds) Neuropeptide systems as targets for parasite and pest control. Springer Nature, Gewerbestrasse, pp 49\u201377"},{"key":"1_CR72","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/j.pt.2016.02.004","volume":"32","author":"P Matou\u0161kov\u00e1","year":"2016","unstructured":"Matou\u0161kov\u00e1 P, Vok\u0159\u00e1l I, Lamka J, Sk\u00e1lov\u00e1 L (2016) The role of xenobiotic-metabolizing enzymes in anthelmintic deactivation and resistance in helminths. Trends Parasitol 32:481\u2013491","journal-title":"Trends Parasitol"},{"key":"1_CR73","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.ijpddr.2011.10.004","volume":"2","author":"P McVeigh","year":"2011","unstructured":"McVeigh P, Atkinson L, Marks NJ, Mousley A, Dalzell JJ, Sluder A, Hammerland L, Maule AG (2011) Parasite neuropeptide biology: seeding rational drug target selection? Int J Parasitol Drugs Drug Resist 2:76\u201391","journal-title":"Int J Parasitol Drugs Drug Resist"},{"key":"1_CR74","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.ijpddr.2018.01.001","volume":"8","author":"P McVeigh","year":"2018","unstructured":"McVeigh P, McCammick E, McCusker P, Wells D, Hodgkinson J, Paterson S, Mousley A, Marks NJ, Maule AG (2018a) Profiling G protein-coupled receptors of Fasciola hepatica identifies orphan rhodopsins unique to phylum Platyhelminthes. Int J Parasitol Drugs Drug Resist 8:87\u2013103","journal-title":"Int J Parasitol Drugs Drug Resist"},{"key":"1_CR75","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1016\/j.pt.2017.11.010","volume":"34","author":"P McVeigh","year":"2018","unstructured":"McVeigh P, McCusker P, Robb E, Wells D, Gardiner E, Mousley A, Marks NJ, Maule AG (2018b) Reasons to be nervous about flukicide discovery. Trends Parasitol 34:184\u2013196","journal-title":"Trends Parasitol"},{"key":"1_CR76","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.molbiopara.2009.04.007","volume":"167","author":"SM Messerli","year":"2009","unstructured":"Messerli SM, Kasinathan RS, Morgan W, Spranger S, Greenberg RM (2009) Schistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibility. Mol Biochem Parasitol 167:54\u201359","journal-title":"Mol Biochem Parasitol"},{"key":"1_CR77","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/s004360050047","volume":"86","author":"J Miquel","year":"2000","unstructured":"Miquel J, Nourrisson C, Marchand B (2000) Ultrastructure of spermiogenesis and the spermatozoon of Opecoeloides furcatus (Trematoda, Digenea, Opecoelidae), a parasite of Mullus barbatus (Pisces, Teleostei). Parasitol Res 86:301\u2013310","journal-title":"Parasitol Res"},{"key":"1_CR78","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.molbiopara.2017.07.001","volume":"216","author":"VA Mordvinov","year":"2017","unstructured":"Mordvinov VA, Ershov NI, Pirozhkova DS, Pakharukov YV, Pakharukova MY (2017) ABC transporters in the liver fluke Opisthorchis felineus. Mol Biochem Parasitol 216:60\u201368","journal-title":"Mol Biochem Parasitol"},{"key":"1_CR79","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.tice.2016.12.007","volume":"49","author":"PI Ndiaye","year":"2017","unstructured":"Ndiaye PI, Quilichini Y, Marigo AM, Ba CT, Tkach VV, Marchand B (2017) Ultrastructural characteristics of the mature spermatozoon of the digenean Sclerodistomum italicum (Stossich, 1893) (Hemiuroidea, Sclerodistomidae) intestinal parasite of Hypocanthus amia (Teleostei, Carangidae). Tissue Cell 49:15\u201321","journal-title":"Tissue Cell"},{"key":"1_CR80","first-page":"117","volume-title":"Advances in trematode biology","author":"PM Nollen","year":"1997","unstructured":"Nollen PM (1997) Reproductive physiology and behavior of digenetic trematodes. In: Fried B, Graczyk TK (eds) Advances in trematode biology. CRC, Boca Raton, pp 117\u2013147"},{"key":"1_CR81","doi-asserted-by":"publisher","first-page":"e0004258","DOI":"10.1371\/journal.pntd.0004258","volume":"9","author":"MY Pakharukova","year":"2015","unstructured":"Pakharukova MY, Vavilin VA, Sripa B, Laha T, Brindley PJ, Mordvinov VA (2015) Functional analysis of the unique cytochrome P450 of the liver fluke Opisthorchis felineus. PLoS Negl Trop Dis 9:e0004258","journal-title":"PLoS Negl Trop Dis"},{"key":"1_CR82","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.molbiopara.2012.11.008","volume":"187","author":"N Patocka","year":"2013","unstructured":"Patocka N, Ribeiro P (2013) The functional role of a serotonin transporter in Schistosoma mansoni elucidated through immunolocalization and RNA interference (RNAi). Mol Biochem Parasitol 187:32\u201342","journal-title":"Mol Biochem Parasitol"},{"key":"1_CR83","doi-asserted-by":"publisher","first-page":"e1003878","DOI":"10.1371\/journal.ppat.1003878","volume":"10","author":"N Patocka","year":"2014","unstructured":"Patocka N, Sharma N, Rashid M, Ribeiro P (2014) Serotonin signaling in Schistosoma mansoni: a serotonin-activated G protein-coupled receptor controls parasite movement. PLoS Pathog 10:e1003878","journal-title":"PLoS Pathog"},{"key":"1_CR84","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/978-1-4939-0915-5_1","volume-title":"Digenetic trematodes","author":"RC Peoples","year":"2014","unstructured":"Peoples RC, Fried B (2014) Form and function in the Digenea. In: Toledo R, Fried B (eds) Digenetic trematodes, 1st edn. Springer, New York, pp 3\u201320","edition":"1"},{"key":"1_CR85","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1017\/S0022149X15000310","volume":"90","author":"A Petrov","year":"2016","unstructured":"Petrov A, Podvyaznaya I (2016) Muscle architecture during the course of development of Diplostomum pseudospathaceum Niewiadomska, 1984 (Trematoda, Diplostomidae) from cercariae to metacercariae. J Helminthol 90:321\u2013336","journal-title":"J Helminthol"},{"key":"1_CR86","doi-asserted-by":"publisher","first-page":"e0140147","DOI":"10.1371\/journal.pone.0140147","volume":"10","author":"A Pinto-Almeida","year":"2015","unstructured":"Pinto-Almeida A, Mendes T, Armada A, Belo S, Carrilho E, Viveiros M, Afonso A (2015) The role of efflux pumps in Schistosoma mansoni praziquantel resistant phenotype. PLoS One 10:e0140147","journal-title":"PLoS One"},{"key":"1_CR87","doi-asserted-by":"publisher","first-page":"e1939","DOI":"10.1371\/journal.pntd.0001939","volume":"6","author":"S Piratae","year":"2012","unstructured":"Piratae S, Tesana S, Jones MK, Brindley PJ, Loukas A, Lovas E, Eursitthichai V, Sripa B, Thanasuwan S, Laha T (2012) Molecular characterization of a tetraspanin from the human liver fluke, Opisthorchis viverrini. PLoS Negl Trop Dis 6:e1939","journal-title":"PLoS Negl Trop Dis"},{"key":"1_CR88","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1007\/s00436-006-0167-2","volume":"99","author":"IM Podvyaznaya","year":"2006","unstructured":"Podvyaznaya IM (2006) An ultrastructural study of alimentary tract development in the cercariae of Diplostomum pseudospathaceum (Digenea: Diplostomidae). Parasitol Res 99:362\u2013367","journal-title":"Parasitol Res"},{"key":"1_CR89","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1111\/j.1463-6395.2010.00486.x","volume":"92","author":"I Podvyaznaya","year":"2011","unstructured":"Podvyaznaya I (2011) An ultrastructural study of alimentary tract development in the cercariae of Prosorhynchoides borealis (Digenea, Bucephalidae). Acta Zool 92:170\u2013178","journal-title":"Acta Zool"},{"key":"1_CR90","doi-asserted-by":"publisher","first-page":"e0005559","DOI":"10.1371\/journal.pntd.0005559","volume":"11","author":"AV Protasio","year":"2017","unstructured":"Protasio AV, van Dongen S, Collins J, Quintais L, Ribeiro DM, Sessler F, Hunt M, Rinaldi G, Collins JJ, Enright AJ, Berriman M (2017) MiR-277\/4989 regulate transcriptional landscape during juvenile to adult transition in the parasitic helminth Schistosoma mansoni. PLoS Negl Trop Dis 11:e0005559","journal-title":"PLoS Negl Trop Dis"},{"key":"1_CR91","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/j.parint.2010.06.002","volume":"59","author":"Y Quilichini","year":"2010","unstructured":"Quilichini Y, Foata J, Justine JL, Bray RA, Marchand B (2010) Ultrastructural study of the spermatozoon of Heterolebes maculosus (Digenea, Opistholebetidae), a parasite of the porcupinefish Diodon hystrix (Pisces, Teleostei). Parasitol Int 59:427\u2013434","journal-title":"Parasitol Int"},{"key":"1_CR92","doi-asserted-by":"publisher","first-page":"S19","DOI":"10.1017\/S0031182005008565","volume":"131","author":"P Ribeiro","year":"2005","unstructured":"Ribeiro P, El-Shehabi F, Patocka N (2005) Classical transmitters and their receptors in flatworms. Parasitology 131:S19\u2013S40","journal-title":"Parasitology"},{"issue":"6","key":"1_CR092","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/j.parint.2013.06.003","volume":"62","author":"Paula Ribeiro","year":"2013","unstructured":"Ribeiro P, Patocka N (2013) Neurotransmitter transporters in schistosomes: structure, function and prospects for drug discovery. Parasitol Int 62:629\u2013638","journal-title":"Parasitology International"},{"key":"1_CR93","first-page":"219","volume-title":"Foundations of parasitology","author":"LS Roberts","year":"2009","unstructured":"Roberts LS, Janovy J Jr (2009) Trematoda: form, function, and classification of Digeneans. In: Roberts LS, Janovy J Jr (eds) Foundations of parasitology, 8th edn. McGraw-Hill, Dubuque, pp 219\u2013245","edition":"8"},{"key":"1_CR94","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1017\/S0031182003004177","volume":"128","author":"H Sato","year":"2004","unstructured":"Sato H, Kusel JR, Thornhill J (2004) Excretion of fluorescent substrates of mammalian multidrug resistance-associated protein (MRP) in the Schistosoma mansoni excretory system. Parasitology 128:43\u201352","journal-title":"Parasitology"},{"key":"1_CR95","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/S0065-308X(06)63003-0","volume":"63","author":"PJ Skelly","year":"2006","unstructured":"Skelly PJ, Wilson AR (2006) Making sense of the schistosome surface. Adv Parasitol 63:185\u2013284","journal-title":"Adv Parasitol"},{"key":"1_CR96","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1080\/14789450.2017.1271327","volume":"14","author":"J Sotillo","year":"2017","unstructured":"Sotillo J, Doolan D, Loukas A (2017) Recent advances in proteomic applications for schistosomiasis research: potential clinical impact. Exp Rev Proteomics 14:171\u2013183","journal-title":"Exp Rev Proteomics"},{"key":"1_CR97","doi-asserted-by":"publisher","first-page":"478","DOI":"10.2478\/s11686-013-0161-7","volume":"58","author":"Z \u015awiderski","year":"2013","unstructured":"\u015awiderski Z, Montoliu I, Feliu C, Gibson DI, Miquel J (2013) A transmission electron microscopical study of the tegument of Maritrema feliui (Digenea: Microphallidae). Acta Parasitol 58:478\u2013485","journal-title":"Acta Parasitol"},{"key":"1_CR98","doi-asserted-by":"publisher","first-page":"1651","DOI":"10.1016\/j.ijpara.2010.07.009","volume":"40","author":"S Takamiya","year":"2010","unstructured":"Takamiya S, Fukuda K, Nakamura T, Aoki T, Sugiyama H (2010) Paragonimus westermani possesses aerobic and anaerobic mitochondria in different tissues, adapting to fluctuating oxygen tension in microaerobic habitats. Int J Parasitol 40:1651\u20131658","journal-title":"Int J Parasitol"},{"key":"1_CR99","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1186\/1756-3305-7-224","volume":"7","author":"S Thanasuwan","year":"2014","unstructured":"Thanasuwan S, Piratae S, Brindley PJ, Loukas A, Kaewkes S, Laha T (2014) Suppression of aquaporin, a mediator of water channel control in the carcinogenic liver fluke, Opisthorchis viverrini. Parasit Vectors 7:224","journal-title":"Parasit Vectors"},{"key":"1_CR100","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/j.parint.2018.04.009","volume":"67","author":"VV Tkach","year":"2018","unstructured":"Tkach VV, Achatz TJ, Hildebrand J, Greiman SE (2018) Convoluted history and confusing morphology: molecular phylogenetic analysis of dicrocoeliids reveals true systematic position of the Anenterotrematidae Yamaguti, 1958 (Platyhelminthes, Digenea). Parasitol Int 67:501\u2013508","journal-title":"Parasitol Int"},{"key":"1_CR101","doi-asserted-by":"publisher","first-page":"123","DOI":"10.2478\/s11686-010-0024-4","volume":"55","author":"OO Tolstenkov","year":"2010","unstructured":"Tolstenkov OO, Terenina NB, Serbina EA, Kreshchenko ND, Maklakova L, Jashina A (2010) The spatial relationship between the musculature and the 5-HT and FMRFamide immunoreactivities in cercaria, metacercaria and adult Opisthorchis felineus (Digenea). Acta Parasitol 55:123\u2013132","journal-title":"Acta Parasitol"},{"key":"1_CR102","doi-asserted-by":"publisher","first-page":"e1000840","DOI":"10.1371\/journal.ppat.1000840","volume":"6","author":"MH Tran","year":"2010","unstructured":"Tran MH, Freitas TC, Cooper L, Gaze S, Gatton ML, Jones MK, Lovas E, Pearce EJ, Loukas A (2010) Suppression of mRNAs encoding tegument tetraspanins from Schistosoma mansoni results in impaired tegument turnover. PLoS Pathog 6:e1000840","journal-title":"PLoS Pathog"},{"key":"1_CR103","unstructured":"Travassos L (1944) [Revis\u00e3o da familia Dicrocoeliidae Odhner, 1910] Imprensa Nacional (in Portuguese)"},{"key":"1_CR104","first-page":"561","volume":"27","author":"L Travassos","year":"1955","unstructured":"Travassos L (1955) S\u00f4bre dois novos Dicrocoeliidae de Chiroptera. An Acad Bras Cienc 27:561\u2013565. (in Portuguese)","journal-title":"An Acad Bras Cienc"},{"key":"1_CR0105","doi-asserted-by":"crossref","unstructured":"Vale N, Gouveia MJ, Rinaldi G, Brindley PJ, G\u00e4rtner F, Correia da Costa JM (2017) Praziquantel for schistosomiasis: single-drug metabolism revisited, mode of action, and resistance. Antimicrob Agents Chemother 61:e02582\u201316","DOI":"10.1128\/AAC.02582-16"},{"key":"1_CR105","doi-asserted-by":"publisher","first-page":"1477","DOI":"10.1016\/S0020-7519(99)00072-7","volume":"29","author":"L Herwerden van","year":"1999","unstructured":"van Herwerden L, Blair D, Agatsuma T (1999) Genetic diversity in parthenogenetic triploid Paragonimus westermani. Int J Parasitol 29:1477\u20131482","journal-title":"Int J Parasitol"},{"key":"1_CR106","doi-asserted-by":"publisher","first-page":"e1004138","DOI":"10.1371\/journal.ppat.1004138","volume":"10","author":"M Vanderstraete","year":"2014","unstructured":"Vanderstraete M, Gouignard N, Cailliau K, Morel M, Hahnel S, Leutner S, Beckmann S, Grevelding CG, Dissous C (2014) Venus kinase receptors control reproduction in the platyhelminth parasite Schistosoma mansoni. PLoS Pathog 10:e1004138","journal-title":"PLoS Pathog"},{"key":"1_CR107","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/S0166-6851(02)00249-9","volume":"126","author":"J Vicogne","year":"2003","unstructured":"Vicogne J, Pin JP, Lardans V, Capron M, Noel C, Dissous C (2003) An unusual receptor tyrosine kinase of Schistosoma mansoni contains a Venus Flytrap module. Mol Biochem Parasitol 126:51\u201362","journal-title":"Mol Biochem Parasitol"},{"key":"1_CR108","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1017\/S0031182000050873","volume":"86","author":"PJ Whitfield","year":"1983","unstructured":"Whitfield PJ, Evans NA (1983) Parthenogenesis and asexual multiplication among parasitic platyhelminths. Parasitology 86:121\u2013160","journal-title":"Parasitology"},{"key":"1_CR109","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.molbiopara.2012.08.008","volume":"186","author":"R Wilkinson","year":"2012","unstructured":"Wilkinson R, Law CJ, Hoey EM, Fairweather I, Brennan GP, Trudgett A (2012) An amino acid substitution in Fasciola hepatica P-glycoprotein from triclabendazole-resistant and triclabendazole-susceptible populations. Mol Biochem Parasitol 186:69\u201372","journal-title":"Mol Biochem Parasitol"},{"key":"1_CR110","doi-asserted-by":"publisher","first-page":"e0004272","DOI":"10.1371\/journal.pntd.0004272","volume":"9","author":"RA Wilson","year":"2015","unstructured":"Wilson RA, Li XH, MacDonald S, Neves LX, Vitoriano-Souza J, Leite LC, Farias LP, James S, Ashton PD, DeMarco R, Castro-Borges W (2015) The schistosome esophagus is a 'hotspot' for microexon and lysosomal hydrolase gene expression: implications for blood processing. PLoS Negl Trop Dis 9:e0004272","journal-title":"PLoS Negl Trop Dis"},{"key":"1_CR111","doi-asserted-by":"publisher","first-page":"13434","DOI":"10.1038\/srep13434","volume":"5","author":"C Wu","year":"2015","unstructured":"Wu C, Hou N, Piao X, Liu S, Cai P, Xiao Y, Chen Q (2015) Non-immune immunoglobulins shield Schistosoma japonicum from host immunorecognition. Sci Rep 5:13434","journal-title":"Sci Rep"},{"key":"1_CR112","doi-asserted-by":"publisher","first-page":"e66396","DOI":"10.1371\/journal.pone.0066396","volume":"8","author":"Y Xiong","year":"2013","unstructured":"Xiong Y, Zhang M, Hong Y, Wei M, Ai D, Meng P, Han Y, Fu Z, Shi Y, Yang J, Lin J (2013) Characterization analysis of Schistosoma japonicum plasma membrane repair relative gene myoferlin. PLoS One 8:e66396","journal-title":"PLoS One"},{"key":"1_CR113","doi-asserted-by":"publisher","first-page":"4378","DOI":"10.1038\/ncomms5378","volume":"5","author":"ND Young","year":"2014","unstructured":"Young ND, Nagarajan N, Lin SJ, Korhonen PK, Jex AR, Hall RS, Safavi-Hemami H, Kaewkong W, Bertrand D, Gao S, Seet Q, Wongkham S, The BT, Wongkham C, Intapan PM, Maleewong W, Yang X, Hu M, Wang Z, Hofmann A, Sternberg PW, Tan P, Wang J, Gasser RB (2014) The Opisthorchis viverrini genome provides insights into life in the bile duct. Nat Commun 5:4378","journal-title":"Nat Commun"},{"key":"1_CR114","doi-asserted-by":"publisher","first-page":"e1005423","DOI":"10.1371\/journal.ppat.1005423","volume":"12","author":"L Zhu","year":"2016","unstructured":"Zhu L, Zhao J, Wang J, Hu C, Peng J, Luo R, Zhou C, Liu J, Lin J, Jin Y, Davis RE, Cheng G (2016) MicroRNAs are involved in the regulation of ovary development in the pathogenic blood fluke Schistosoma japonicum. PLoS Pathog 12:e1005423","journal-title":"PLoS Pathog"}],"container-title":["Advances in Experimental Medicine and Biology","Digenetic Trematodes"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-030-18616-6_1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,11]],"date-time":"2019-07-11T21:09:24Z","timestamp":1562879364000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-030-18616-6_1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"ISBN":["9783030186159","9783030186166"],"references-count":118,"URL":"https:\/\/doi.org\/10.1007\/978-3-030-18616-6_1","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"type":"print","value":"0065-2598"},{"type":"electronic","value":"2214-8019"}],"subject":[],"published":{"date-parts":[[2019]]},"assertion":[{"value":"12 July 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}