{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T19:12:28Z","timestamp":1779909148745,"version":"3.53.1"},"publisher-location":"Cham","reference-count":270,"publisher":"Springer International Publishing","isbn-type":[{"value":"9783030511395","type":"print"},{"value":"9783030511401","type":"electronic"}],"license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021]]},"DOI":"10.1007\/978-3-030-51140-1_11","type":"book-chapter","created":{"date-parts":[[2021,1,13]],"date-time":"2021-01-13T00:30:34Z","timestamp":1610497834000},"page":"151-176","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Progressive Supranuclear Palsy and Corticobasal Degeneration"],"prefix":"10.1007","author":[{"given":"David G.","family":"Coughlin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis W.","family":"Dickson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith A.","family":"Josephs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Litvan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,1,13]]},"reference":[{"issue":"2","key":"11_CR1","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1007\/s00401-011-0839-6","volume":"122","author":"KA Josephs","year":"2011","unstructured":"Josephs KA, Hodges JR, Snowden JS, Mackenzie IR, Neumann M, Mann DM et al (2011) Neuropathological background of phenotypical variability in frontotemporal dementia. Acta Neuropathol 122(2):137\u2013153","journal-title":"Acta Neuropathol"},{"issue":"6","key":"11_CR2","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1016\/S1474-4422(13)70090-5","volume":"12","author":"MG Spillantini","year":"2013","unstructured":"Spillantini MG, Goedert M (2013) Tau pathology and neurodegeneration. Lancet Neurol 12(6):609\u2013622","journal-title":"Lancet Neurol"},{"key":"11_CR3","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1017\/CBO9780511526886.012","volume-title":"The neuropathology of dementia","author":"DW Dickson","year":"2004","unstructured":"Dickson DW (2004) Sporadic tauopathies: Pick\u2019s disease, corticobasal degeneration, progressive suprnauclear palsy and argyrophilic grain disease. In: Esiri MM, Lee VMY, Trojanowski JQ (eds) The neuropathology of dementia, 2nd edn. Cambridge University Press, Cambridge\/New York, pp 227\u2013256","edition":"2"},{"issue":"7752","key":"11_CR4","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1038\/s41586-019-1026-5","volume":"568","author":"B Falcon","year":"2019","unstructured":"Falcon B, Zivanov J, Zhang W, Murzin AG, Garringer HJ, Vidal R et al (2019) Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules. Nature 568(7752):420\u2013423","journal-title":"Nature"},{"issue":"7662","key":"11_CR5","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1038\/nature23002","volume":"547","author":"AWP Fitzpatrick","year":"2017","unstructured":"Fitzpatrick AWP, Falcon B, He S, Murzin AG, Murshudov G, Garringer HJ et al (2017) Cryo-EM structures of tau filaments from Alzheimer\u2019s disease. Nature 547(7662):185\u2013190","journal-title":"Nature"},{"issue":"1","key":"11_CR6","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1007\/s00401-015-1509-x","volume":"131","author":"GG Kovacs","year":"2016","unstructured":"Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H et al (2016) Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy. Acta Neuropathol 131(1):87\u2013102","journal-title":"Acta Neuropathol"},{"issue":"6","key":"11_CR7","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1093\/jnen\/61.6.547","volume":"61","author":"T Togo","year":"2002","unstructured":"Togo T, Sahara N, Yen SH, Cookson N, Ishizawa T, Hutton M et al (2002) Argyrophilic grain disease is a sporadic 4-repeat tauopathy. J Neuropathol Exp Neurol 61(6):547\u2013556","journal-title":"J Neuropathol Exp Neurol"},{"key":"11_CR8","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1001\/archneur.1964.00460160003001","volume":"10","author":"JC Steele","year":"1964","unstructured":"Steele JC, Richardson JC, Olszewski J (1964) Progressive supranuclear palsy. A heterogenous degeneration involving the brain stem, basal ganglia and cerebellum with vertical gaze and pseudobulbar palsy, nuchal dystonia and dementia. Arch Neurol 10:333\u2013359","journal-title":"Arch Neurol"},{"key":"11_CR9","doi-asserted-by":"publisher","first-page":"xvii","DOI":"10.1002\/9781444341256","volume-title":"Neurodegeneration: the molecular pathology of dementia and movement disorders","author":"DW Dickson","year":"2011","unstructured":"Dickson DW, Hauw J-J, Agid Y, Litvan I (2011) Progressive supranuclear palsy and corticobasal degeneration. In: Dickson DW, Weller RO (eds) Neurodegeneration: the molecular pathology of dementia and movement disorders, 2nd edn. Wiley-Blackwell\/International Society of Neuropathology, Chichester\/West Sussex, p xvii, 477 p.","edition":"2"},{"issue":"7","key":"11_CR10","doi-asserted-by":"publisher","first-page":"1438","DOI":"10.1093\/brain\/124.7.1438","volume":"124","author":"U Nath","year":"2001","unstructured":"Nath U, Ben-Shlomo Y, Thomson R, Morris HR, Wood N, Lees A et al (2001) The prevalence of progressive supranuclear palsy (Steele\u2013Richardson\u2013Olszewski syndrome) in the UK. Brain 124(7):1438\u20131449","journal-title":"Brain"},{"issue":"18","key":"11_CR11","doi-asserted-by":"publisher","first-page":"1736","DOI":"10.1212\/WNL.0000000000002638","volume":"86","author":"IT Coyle-Gilchrist","year":"2016","unstructured":"Coyle-Gilchrist IT, Dick KM, Patterson K, Rodr\u00edquez PV, Wehmann E, Wilcox A et al (2016) Prevalence, characteristics, and survival of frontotemporal lobar degeneration syndromes. Neurology 86(18):1736\u20131743","journal-title":"Neurology"},{"issue":"9192","key":"11_CR12","doi-asserted-by":"publisher","first-page":"1771","DOI":"10.1016\/S0140-6736(99)04137-9","volume":"354","author":"A Schrag","year":"1999","unstructured":"Schrag A, Ben-Shlomo Y, Quinn N (1999) Prevalence of progressive supranuclear palsy and multiple system atrophy: a cross-sectional study. Lancet 354(9192):1771\u20131775","journal-title":"Lancet"},{"issue":"7","key":"11_CR13","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1002\/mds.27034","volume":"32","author":"G Respondek","year":"2017","unstructured":"Respondek G, Kurz C, Arzberger T, Compta Y, Englund E, Ferguson LW et al (2017) Which ante mortem clinical features predict progressive supranuclear palsy pathology? Mov Disord 32(7):995\u20131005","journal-title":"Mov Disord"},{"key":"11_CR14","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.parkreldis.2018.03.030","volume":"54","author":"V Fleury","year":"2018","unstructured":"Fleury V, Brindel P, Nicastro N, Burkhard PR (2018) Descriptive epidemiology of parkinsonism in the Canton of Geneva, Switzerland. Parkinsonism Relat Disord 54:30\u201339","journal-title":"Parkinsonism Relat Disord"},{"issue":"10","key":"11_CR15","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1002\/mds.20149","volume":"19","author":"M Kawashima","year":"2004","unstructured":"Kawashima M, Miyake M, Kusumi M, Adachi Y, Nakashima K (2004) Prevalence of progressive supranuclear palsy in Yonago, Japan. Mov Disord: Off J Mov Disord Soc 19(10):1239\u20131240","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"key":"11_CR16","doi-asserted-by":"publisher","first-page":"e120","DOI":"10.1016\/j.parkreldis.2015.10.282","volume":"22","author":"H Takigawa","year":"2016","unstructured":"Takigawa H, Ikeuchi T, Aiba I, Morita M, Onodera O, Shimohata T et al (2016) Japanese longitudinal biomarker study in PSP and CBD (JALPAC): a prospective multicenter PSP\/CBD cohort study in Japan. Parkinsonism Relat Disord 22:e120\u2013e1e1","journal-title":"Parkinsonism Relat Disord"},{"key":"11_CR17","unstructured":"H\u00f6glinger GU, Respondek G, Stamelou M, Kurz C, Josephs KA, Lang AE et al (2017) Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria. Mov Disord:n\/a\u2013n\/a"},{"issue":"1","key":"11_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1212\/WNL.47.1.1","volume":"47","author":"I Litvan","year":"1996","unstructured":"Litvan I, Agid Y, Calne D, Campbell G, Dubois B, Duvoisin RC et al (1996) Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): report of the NINDS-SPSP international workshop. Neurology 47(1):1\u20139","journal-title":"Neurology"},{"issue":"14","key":"11_CR19","doi-asserted-by":"publisher","first-page":"1758","DOI":"10.1002\/mds.26054","volume":"29","author":"G Respondek","year":"2014","unstructured":"Respondek G, Stamelou M, Kurz C, Ferguson LW, Rajput A, Chiu WZ et al (2014) The phenotypic spectrum of progressive supranuclear palsy: a retrospective multicenter study of 100 definite cases. Mov Disord: Off J Mov Disord Soc 29(14):1758\u20131766","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"6","key":"11_CR20","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1136\/jnnp.60.6.615","volume":"60","author":"I Litvan","year":"1996","unstructured":"Litvan I, Mangone CA, McKee A, Verny M, Parsa A, Jellinger K et al (1996) Natural history of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome) and clinical predictors of survival: a clinicopathological study. J Neurol Neurosurg Psychiatry 60(6):615\u2013620","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"7","key":"11_CR21","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1212\/WNL.36.7.1005","volume":"36","author":"E Maher","year":"1986","unstructured":"Maher E, Lees A (1986) The clinical features and natural history of the Steele-Richardson-Olszewski syndrome (progressive supranuclear palsy). Neurology 36(7):1005","journal-title":"Neurology"},{"issue":"7","key":"11_CR22","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1212\/WNL.38.7.1031","volume":"38","author":"LI Golbe","year":"1988","unstructured":"Golbe LI, Davis PH, Schoenberg BS, Duvoisin RC (1988) Prevalence and natural history of progressive supranuclear palsy. Neurology 38(7):1031","journal-title":"Neurology"},{"key":"11_CR23","volume-title":"Progressive supranuclear palsy: clinical and research approaches","author":"I Litvan","year":"1992","unstructured":"Litvan I, Agid Y (1992) Progressive supranuclear palsy: clinical and research approaches. Oxford University Press, New York"},{"issue":"2","key":"11_CR24","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1136\/jnnp.58.2.167","volume":"58","author":"S Collins","year":"1995","unstructured":"Collins S, Ahlskog J, Parisi JE, Maraganore D (1995) Progressive supranuclear palsy: neuropathologically based diagnostic clinical criteria. J Neurol Neurosurg Psychiatry 58(2):167\u2013173","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"1","key":"11_CR25","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1016\/0002-9394(71)90409-0","volume":"71","author":"W Chamberlain","year":"1971","unstructured":"Chamberlain W (1971) Restriction in upward gaze with advancing age. Am J Ophthalmol 71(1):341\u2013346","journal-title":"Am J Ophthalmol"},{"issue":"4","key":"11_CR26","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1002\/ana.410350408","volume":"35","author":"M Vidailhet","year":"1994","unstructured":"Vidailhet M, Rivaud S, Gouider-Khouja N, Pillon B, Bonnet AM, Gaymard B et al (1994) Eye movements in parkinsonian syndromes. Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc 35(4):420\u2013426","journal-title":"Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc"},{"issue":"5","key":"11_CR27","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1093\/brain\/110.5.1131","volume":"110","author":"W Gibb","year":"1987","unstructured":"Gibb W, Esiri M, Lees A (1987) Clinical and pathological features of diffuse cortical Lewy body disease (Lewy body dementia). Brain 110(5):1131\u20131153","journal-title":"Brain"},{"issue":"2","key":"11_CR28","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1002\/ana.410340215","volume":"34","author":"MP Grant","year":"1993","unstructured":"Grant MP, Cohen M, Petersen RB, Halmagyi GM, McDougall A, Tusa RJ et al (1993) Abnormal eye movements in Creutzfeldt\u2013Jakob disease. Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc 34(2):192\u2013197","journal-title":"Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc"},{"key":"11_CR29","doi-asserted-by":"crossref","unstructured":"Paulson H, Subramony S (2003) Spinocerebellar Ataxia 3\u2014Machado-Joseph disease (SCA3). In: Genetics of movement disorders. Elsevier, pp 57\u201369","DOI":"10.1016\/B978-012566652-7\/50007-1"},{"issue":"5","key":"11_CR30","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1002\/mds.26608","volume":"31","author":"N Br\u00fcggemann","year":"2016","unstructured":"Br\u00fcggemann N, Wandinger KP, Gaig C, Sprenger A, Junghanns K, Helmchen C et al (2016) Dystonia, lower limb stiffness, and upward gaze palsy in a patient with IgLON5 antibodies. Mov Disord 31(5):762\u2013764","journal-title":"Mov Disord"},{"issue":"4","key":"11_CR31","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1001\/archneurol.2011.56","volume":"68","author":"C Adams","year":"2011","unstructured":"Adams C, McKeon A, Silber MH, Kumar R (2011) Narcolepsy, REM sleep behavior disorder, and supranuclear gaze palsy associated with Ma1 and Ma2 antibodies and tonsillar carcinoma. Arch Neurol 68(4):521\u2013524","journal-title":"Arch Neurol"},{"key":"11_CR32","doi-asserted-by":"publisher","first-page":"S192","DOI":"10.1016\/S1353-8020(11)70060-8","volume":"18","author":"BF Boeve","year":"2012","unstructured":"Boeve BF (2012) Progressive supranuclear palsy. Parkinsonism Relat Disord 18:S192\u2013S1S4","journal-title":"Parkinsonism Relat Disord"},{"issue":"10","key":"11_CR33","doi-asserted-by":"publisher","first-page":"1386","DOI":"10.1136\/jnnp.2003.027367","volume":"75","author":"S Garbutt","year":"2004","unstructured":"Garbutt S, Riley D, Kumar A, Han Y, Harwood M, Leigh R (2004) Abnormalities of optokinetic nystagmus in progressive supranuclear palsy. J Neurol Neurosurg Psychiatry 75(10):1386\u20131394","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"6","key":"11_CR34","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1002\/ana.410400630","volume":"40","author":"N Quinn","year":"1996","unstructured":"Quinn N (1996) The \u201cround the houses\u201d sign in progressive supranuclear palsy. Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc 40(6):951","journal-title":"Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc"},{"key":"11_CR35","doi-asserted-by":"crossref","unstructured":"Lal V, Truong D (2019) Eye movement in movement disorders. Clin Parkinsonism Relat Disord 1:54\u201363","DOI":"10.1016\/j.prdoa.2019.08.004"},{"issue":"1","key":"11_CR36","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1111\/j.1749-6632.2002.tb02867.x","volume":"956","author":"K Kitthaweesin","year":"2002","unstructured":"Kitthaweesin K, Riley DE, Leigh RJ (2002) Vergence disorders in progressive supranuclear palsy. Ann New York Acad Sci 956(1):504\u2013507","journal-title":"Ann New York Acad Sci"},{"issue":"2","key":"11_CR37","doi-asserted-by":"publisher","first-page":"159","DOI":"10.3988\/jcn.2005.1.2.159","volume":"1","author":"WT Yoon","year":"2005","unstructured":"Yoon WT, Chung EJ, Lee SH, Kim BJ, Lee WY (2005) Clinical analysis of blepharospasm and apraxia of eyelid opening in patients with parkinsonism. J Clin Neurol 1(2):159\u2013165","journal-title":"J Clin Neurol"},{"issue":"4","key":"11_CR38","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1136\/jnnp.2005.074070","volume":"77","author":"DR Williams","year":"2006","unstructured":"Williams DR, Watt HC, Lees AJ (2006) Predictors of falls and fractures in bradykinetic rigid syndromes: a retrospective study. J Neurol Neurosurg Psychiatry 77(4):468\u2013473","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"3 Part 1","key":"11_CR39","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1212\/WNL.43.3_Part_1.563","volume":"43","author":"KJ Kluin","year":"1993","unstructured":"Kluin KJ, Foster NL, Berent S, Gilman S (1993) Perceptual analysis of speech disorders in progressive supranuclear palsy. Neurology 43(3 Part 1):563","journal-title":"Neurology"},{"issue":"2","key":"11_CR40","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1001\/archneur.58.2.259","volume":"58","author":"J M\u00fcller","year":"2001","unstructured":"M\u00fcller J, Wenning GK, Verny M, McKee A, Chaudhuri KR, Jellinger K et al (2001) Progression of dysarthria and dysphagia in postmortem-confirmed parkinsonian disorders. Arch Neurol 58(2):259\u2013264","journal-title":"Arch Neurol"},{"issue":"7","key":"11_CR41","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1016\/j.parkreldis.2005.06.003","volume":"11","author":"S Papapetropoulos","year":"2005","unstructured":"Papapetropoulos S, Singer C, McCorquodale D, Gonzalez J, Mash DC (2005) Cause, seasonality of death and co-morbidities in progressive supranuclear palsy (PSP). Parkinsonism Relat Disord 11(7):459\u2013463","journal-title":"Parkinsonism Relat Disord"},{"issue":"1","key":"11_CR42","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1097\/00005072-199601000-00010","volume":"55","author":"I Litvan","year":"1996","unstructured":"Litvan I, Hauw J, Bartko J, Lantos P, Daniel S, Horoupian D et al (1996) Validity and reliability of the preliminary NINDS neuropathologic criteria for progressive supranuclear palsy and related disorders. J Neuropathol Exp Neurol 55(1):97\u2013105","journal-title":"J Neuropathol Exp Neurol"},{"issue":"4","key":"11_CR43","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1002\/mds.25327","volume":"28","author":"G Respondek","year":"2013","unstructured":"Respondek G, Roeber S, Kretzschmar H, Troakes C, Al-Sarraj S, Gelpi E et al (2013) Accuracy of the National Institute for Neurological Disorders and Stroke\/Society for Progressive Supranuclear Palsy and neuroprotection and natural history in Parkinson plus syndromes criteria for the diagnosis of progressive supranuclear palsy. Mov Disord: Off J Mov Disord Soc 28(4):504\u2013509","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"2","key":"11_CR44","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1002\/mds.10680","volume":"19","author":"Y Osaki","year":"2004","unstructured":"Osaki Y, Ben-Shlomo Y, Lees AJ, Daniel SE, Colosimo C, Wenning G et al (2004) Accuracy of clinical diagnosis of progressive supranuclear palsy. Mov Disord 19(2):181\u2013189","journal-title":"Mov Disord"},{"issue":"6","key":"11_CR45","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1002\/mds.10211","volume":"17","author":"S Birdi","year":"2002","unstructured":"Birdi S, Rajput AH, Fenton M, Donat JR, Rozdilsky B, Robinson C et al (2002) Progressive supranuclear palsy diagnosis and confounding features: report on 16 autopsied cases. Mov Disord: Off J Mov Disord Soc 17(6):1255\u20131264","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"Pt 6","key":"11_CR46","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1093\/brain\/awh488","volume":"128","author":"DR Williams","year":"2005","unstructured":"Williams DR, de Silva R, Paviour DC, Pittman A, Watt HC, Kilford L et al (2005) Characteristics of two distinct clinical phenotypes in pathologically proven progressive supranuclear palsy: Richardson\u2019s syndrome and PSP-parkinsonism. Brain 128(Pt 6):1247\u20131258","journal-title":"Brain"},{"issue":"15","key":"11_CR47","doi-asserted-by":"publisher","first-page":"2235","DOI":"10.1002\/mds.21698","volume":"22","author":"DR Williams","year":"2007","unstructured":"Williams DR, Holton JL, Strand K, Revesz T, Lees AJ (2007) Pure akinesia with gait freezing: a third clinical phenotype of progressive supranuclear palsy. Mov Disord: Off J Mov Disord Soc 22(15):2235\u20132241","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"2","key":"11_CR48","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1159\/000068502","volume":"49","author":"B Boeve","year":"2003","unstructured":"Boeve B, Dickson D, Duffy J, Bartleson J, Trenerry M, Petersen R (2003) Progressive nonfluent aphasia and subsequent aphasic dementia associated with atypical progressive supranuclear palsy pathology. Eur Neurol 49(2):72\u201378","journal-title":"Eur Neurol"},{"issue":"4","key":"11_CR49","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1212\/WNL.53.4.795","volume":"53","author":"BF Boeve","year":"1999","unstructured":"Boeve BF, Maraganore D, Parisi JE, Ahlskog J, Graff-Radford N, Caselli RJ et al (1999) Pathologic heterogeneity in clinically diagnosed corticobasal degeneration. Neurology 53(4):795","journal-title":"Neurology"},{"issue":"4","key":"11_CR50","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1097\/01.jnen.0000218446.38158.61","volume":"65","author":"KA Josephs","year":"2006","unstructured":"Josephs KA, Katsuse O, Beccano-Kelly DA, Lin W-L, Uitti RJ, Fujino Y et al (2006) Atypical progressive supranuclear palsy with corticospinal tract degeneration. J Neuropathol Exp Neurol 65(4):396\u2013405","journal-title":"J Neuropathol Exp Neurol"},{"issue":"5","key":"11_CR51","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1002\/mds.26499","volume":"31","author":"S Koga","year":"2016","unstructured":"Koga S, Josephs KA, Ogaki K, Labb\u00e9 C, Uitti RJ, Graff-Radford N et al (2016) Cerebellar ataxia in progressive supranuclear palsy: an autopsy study of PSP-C. Mov Disord 31(5):653\u2013662","journal-title":"Mov Disord"},{"issue":"6","key":"11_CR52","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1097\/WCO.0b013e3283168ddd","volume":"21","author":"KA Josephs","year":"2008","unstructured":"Josephs KA, Duffy JR (2008) Apraxia of speech and nonfluent aphasia: a new clinical marker for corticobasal degeneration and progressive supranuclear palsy. Curr Opin Neurol 21(6):688\u2013692","journal-title":"Curr Opin Neurol"},{"issue":"6","key":"11_CR53","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1080\/13554794.2011.627345","volume":"18","author":"A Hassan","year":"2012","unstructured":"Hassan A, Parisi JE, Josephs KA (2012) Autopsy-proven progressive supranuclear palsy presenting as behavioral variant frontotemporal dementia. Neurocase 18(6):478\u2013488","journal-title":"Neurocase"},{"issue":"3","key":"11_CR54","doi-asserted-by":"publisher","first-page":"148","DOI":"10.3988\/jcn.2010.6.3.148","volume":"6","author":"HJ Han","year":"2010","unstructured":"Han HJ, Kim H, Park JH, Shin HW, Kim GU, Kim DS et al (2010) Behavioral changes as the earliest clinical manifestation of progressive supranuclear palsy. J Clin Neurol (Seoul, Korea) 6(3):148\u2013151","journal-title":"J Clin Neurol (Seoul, Korea)"},{"issue":"7","key":"11_CR55","doi-asserted-by":"publisher","first-page":"2045","DOI":"10.1093\/brain\/awq123","volume":"133","author":"H Ling","year":"2010","unstructured":"Ling H, O\u2019Sullivan SS, Holton JL, Revesz T, Massey LA, Williams DR et al (2010) Does corticobasal degeneration exist? A clinicopathological re-evaluation. Brain 133(7):2045\u20132057","journal-title":"Brain"},{"issue":"2","key":"11_CR56","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1111\/nan.12037","volume":"40","author":"H Ling","year":"2014","unstructured":"Ling H, De Silva R, Massey L, Courtney R, Hondhamuni G, Bajaj N et al (2014) Characteristics of progressive supranuclear palsy presenting with corticobasal syndrome: a cortical variant. Neuropathol Appl Neurobiol 40(2):149\u2013163","journal-title":"Neuropathol Appl Neurobiol"},{"issue":"1\u20132","key":"11_CR57","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.jns.2012.09.005","volume":"323","author":"S Nagao","year":"2012","unstructured":"Nagao S, Yokota O, Nanba R, Takata H, Haraguchi T, Ishizu H et al (2012) Progressive supranuclear palsy presenting as primary lateral sclerosis but lacking parkinsonism, gaze palsy, aphasia, or dementia. J Neurol Sci 323(1\u20132):147\u2013153","journal-title":"J Neurol Sci"},{"key":"11_CR58","doi-asserted-by":"publisher","first-page":"S34","DOI":"10.1016\/j.parkreldis.2015.09.041","volume":"22","author":"G Respondek","year":"2016","unstructured":"Respondek G, H\u00f6glinger G (2016) The phenotypic spectrum of progressive supranuclear palsy. Parkinsonism Relat Disord 22:S34\u2013SS6","journal-title":"Parkinsonism Relat Disord"},{"issue":"Pt 4","key":"11_CR59","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1093\/brain\/awf080","volume":"125","author":"AJ Hughes","year":"2002","unstructured":"Hughes AJ, Daniel SE, Ben-Shlomo Y, Lees AJ (2002) The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service. Brain 125(Pt 4):861\u2013870","journal-title":"Brain"},{"issue":"3","key":"11_CR60","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","volume":"55","author":"AJ Hughes","year":"1992","unstructured":"Hughes AJ, Daniel SE, Kilford L, Lees AJ (1992) Accuracy of clinical diagnosis of idiopathic Parkinson\u2019s disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 55(3):181\u2013184","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"6","key":"11_CR61","doi-asserted-by":"publisher","first-page":"1566","DOI":"10.1093\/brain\/awm104","volume":"130","author":"DR Williams","year":"2007","unstructured":"Williams DR, Holton JL, Strand C, Pittman A, de Silva R, Lees AJ et al (2007) Pathological tau burden and distribution distinguishes progressive supranuclear palsy-parkinsonism from Richardson\u2019s syndrome. Brain 130(6):1566\u20131576","journal-title":"Brain"},{"issue":"3","key":"11_CR62","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1002\/mds.22977","volume":"25","author":"DR Williams","year":"2010","unstructured":"Williams DR, Lees AJ (2010) What features improve the accuracy of the clinical diagnosis of progressive supranuclear palsy-parkinsonism (PSP-P)? Mov Disord 25(3):357\u2013362","journal-title":"Mov Disord"},{"issue":"5","key":"11_CR63","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1212\/WNL.0000000000000641","volume":"83","author":"CH Adler","year":"2014","unstructured":"Adler CH, Beach TG, Hentz JG, Shill HA, Caviness JN, Driver-Dunckley E et al (2014) Low clinical diagnostic accuracy of early vs advanced Parkinson disease: clinicopathologic study. Neurology 83(5):406\u2013412","journal-title":"Neurology"},{"key":"11_CR64","first-page":"25","volume":"88","author":"J Richardson","year":"1963","unstructured":"Richardson J, Steele J, Olszewski J (1963) Supranuclear opthalmoplegia, pseudobulbar palsy, nuchal dystonia and dementia. A clinical report on eight cases of \u201cheterogeneous system degeneration\u201d. Trans Am Neurol Assoc 88:25","journal-title":"Trans Am Neurol Assoc"},{"issue":"4","key":"11_CR65","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1097\/00002826-199308000-00006","volume":"16","author":"KA Nieforth","year":"1993","unstructured":"Nieforth KA, Golbe LI (1993) Retrospective study of drug response in 87 patients with progressive supranuclear palsy. Clin Neuropharmacol 16(4):338\u2013346","journal-title":"Clin Neuropharmacol"},{"issue":"2","key":"11_CR66","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/S0303-8467(02)00128-2","volume":"105","author":"E Tan","year":"2003","unstructured":"Tan E, Chan L, Wong M (2003) Levodopa-induced oromandibular dystonia in progressive supranuclear palsy. Clin Neurol Neurosurg 105(2):132\u2013134","journal-title":"Clin Neurol Neurosurg"},{"issue":"S12","key":"11_CR67","doi-asserted-by":"publisher","first-page":"S83","DOI":"10.1002\/mds.20545","volume":"20","author":"AE Lang","year":"2005","unstructured":"Lang AE (2005) Treatment of progressive supranuclear palsy and corticobasal degeneration. Mov Disord: Off J Mov Disord Soc 20(S12):S83\u2013S91","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"5","key":"11_CR68","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1002\/mds.10459","volume":"18","author":"I Litvan","year":"2003","unstructured":"Litvan I, Bhatia KP, Burn DJ, Goetz CG, Lang AE, McKeith I et al (2003) Movement disorders society scientific issues committee report: SIC task force appraisal of clinical diagnostic criteria for parkinsonian disorders. Mov Disord: Off J Mov Disord Soc 18(5):467\u2013486","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"8","key":"11_CR69","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1212\/01.wnl.0000267643.24870.26","volume":"69","author":"L Donker Kaat","year":"2007","unstructured":"Donker Kaat L, Boon AJ, Kamphorst W, Ravid R, Duivenvoorden HJ, van Swieten JC (2007) Frontal presentation in progressive supranuclear palsy. Neurology 69(8):723\u2013729","journal-title":"Neurology"},{"issue":"1","key":"11_CR70","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1212\/01.wnl.0000191307.69661.c3","volume":"66","author":"KA Josephs","year":"2006","unstructured":"Josephs KA, Petersen RC, Knopman DS, Boeve BF, Whitwell JL, Duffy JR et al (2006) Clinicopathologic analysis of frontotemporal and corticobasal degenerations and PSP. Neurology 66(1):41\u201348","journal-title":"Neurology"},{"issue":"6","key":"11_CR71","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1007\/s00401-003-0682-5","volume":"105","author":"A Mochizuki","year":"2003","unstructured":"Mochizuki A, Ueda Y, Komatsuzaki Y, Tsuchiya K, Arai T, Shoji S (2003) Progressive supranuclear palsy presenting with primary progressive aphasia--clinicopathological report of an autopsy case. Acta Neuropathol 105(6):610\u2013614","journal-title":"Acta Neuropathol"},{"issue":"8","key":"11_CR72","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1002\/mds.20478","volume":"20","author":"Y Tsuboi","year":"2005","unstructured":"Tsuboi Y, Josephs KA, Boeve BF, Litvan I, Caselli RJ, Caviness JN et al (2005) Increased tau burden in the cortices of progressive supranuclear palsy presenting with corticobasal syndrome. Mov Disord 20(8):982\u2013988","journal-title":"Mov Disord"},{"issue":"13","key":"11_CR73","doi-asserted-by":"publisher","first-page":"1954","DOI":"10.1002\/mds.21612","volume":"22","author":"Y Compta","year":"2007","unstructured":"Compta Y, Valldeoriola F, Tolosa E, Rey MJ, Mart\u00ed MJ, Valls-Sol\u00e9 J (2007) Long lasting pure freezing of gait preceding progressive supranuclear palsy: a clinicopathological study. Mov Disord 22(13):1954\u20131958","journal-title":"Mov Disord"},{"issue":"6","key":"11_CR74","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/j.parkreldis.2007.11.004","volume":"14","author":"MF Facheris","year":"2008","unstructured":"Facheris MF, Maniak S, Scaravilli F, Sch\u00fcle B, Klein C, Pramstaller PP (2008) Pure akinesia as initial presentation of PSP: a clinicopathological study. Parkinsonism Relat Disord 14(6):517\u2013519","journal-title":"Parkinsonism Relat Disord"},{"issue":"1","key":"11_CR75","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-016-0391-7","volume":"4","author":"C Kurz","year":"2016","unstructured":"Kurz C, Ebersbach G, Respondek G, Giese A, Arzberger T, H\u00f6glinger GU (2016) An autopsy-confirmed case of progressive supranuclear palsy with predominant postural instability. Acta Neuropathol Commun 4(1):120","journal-title":"Acta Neuropathol Commun"},{"issue":"9","key":"11_CR76","doi-asserted-by":"publisher","first-page":"1312","DOI":"10.1002\/mds.22583","volume":"24","author":"M Kanazawa","year":"2009","unstructured":"Kanazawa M, Shimohata T, Toyoshima Y, Tada M, Kakita A, Morita T et al (2009) Cerebellar involvement in progressive supranuclear palsy: a clinicopathological study. Mov Disord: Off J Mov Disord Soc 24(9):1312\u20131318","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"12","key":"11_CR77","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1016\/j.parkreldis.2013.07.019","volume":"19","author":"M Kanazawa","year":"2013","unstructured":"Kanazawa M, Tada M, Onodera O, Takahashi H, Nishizawa M, Shimohata T (2013) Early clinical features of patients with progressive supranuclear palsy with predominant cerebellar ataxia. Parkinsonism Relat Disord 19(12):1149\u20131151","journal-title":"Parkinsonism Relat Disord"},{"key":"11_CR78","doi-asserted-by":"crossref","unstructured":"Ali F, Martin PR, Botha H, Ahlskog JE, Bower JH, Masumoto JY et al (2019) Sensitivity and specificity of diagnostic criteria for progressive supranuclear palsy. Mov Disord 34(8):1144\u20131153","DOI":"10.1002\/mds.27619"},{"issue":"6","key":"11_CR79","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1002\/mdc3.12807","volume":"6","author":"F Ali","year":"2019","unstructured":"Ali F, Botha H, Whitwell JL, Josephs KA (2019) Utility of the movement disorders society criteria for progressive supranuclear palsy in clinical practice. Mov Disord Clin Pract 6(6):436\u2013439","journal-title":"Mov Disord Clin Pract"},{"key":"11_CR80","doi-asserted-by":"crossref","unstructured":"Shoeibi A, Litvan I, Juncos JL, Bordelon Y, Riley D, Standaert D et al (2019) Are the International Parkinson disease and Movement Disorder Society progressive supranuclear palsy (IPMDS-PSP) diagnostic criteria accurate enough to differentiate common PSP phenotypes? Parkinsonism Relat Disord. In Press","DOI":"10.1016\/j.parkreldis.2019.10.012"},{"issue":"Pt 2","key":"11_CR81","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1093\/brain\/awm301","volume":"131","author":"Z Ahmed","year":"2008","unstructured":"Ahmed Z, Josephs KA, Gonzalez J, DelleDonne A, Dickson DW (2008) Clinical and neuropathologic features of progressive supranuclear palsy with severe pallido-nigro-luysial degeneration and axonal dystrophy. Brain 131(Pt 2):460\u2013472","journal-title":"Brain"},{"issue":"4","key":"11_CR82","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1097\/WCO.0b013e32833be924","volume":"23","author":"DW Dickson","year":"2010","unstructured":"Dickson DW, Ahmed Z, Algom AA, Tsuboi Y, Josephs KA (2010) Neuropathology of variants of progressive supranuclear palsy. Curr Opin Neurol 23(4):394\u2013400","journal-title":"Curr Opin Neurol"},{"issue":"6","key":"11_CR83","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1093\/jnen\/59.6.513","volume":"59","author":"K Ishizawa","year":"2000","unstructured":"Ishizawa K, Lin WL, Tiseo P, Honer WG, Davies P, Dickson DW (2000) A qualitative and quantitative study of grumose degeneration in progressive supranuclear palsy. J Neuropathol Exp Neurol 59(6):513\u2013524","journal-title":"J Neuropathol Exp Neurol"},{"issue":"6","key":"11_CR84","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1093\/jnen\/60.6.647","volume":"60","author":"K Ishizawa","year":"2001","unstructured":"Ishizawa K, Dickson DW (2001) Microglial activation parallels system degeneration in progressive supranuclear palsy and corticobasal degeneration. J Neuropathol Exp Neurol 60(6):647\u2013657","journal-title":"J Neuropathol Exp Neurol"},{"issue":"Pt 5","key":"11_CR85","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1093\/brain\/112.5.1171","volume":"112","author":"WR Gibb","year":"1989","unstructured":"Gibb WR, Luthert PJ, Marsden CD (1989) Corticobasal degeneration. Brain 112(Pt 5):1171\u20131192","journal-title":"Brain"},{"issue":"3\u20134","key":"11_CR86","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1007\/BF00688042","volume":"71","author":"DW Dickson","year":"1986","unstructured":"Dickson DW, Yen SH, Suzuki KI, Davies P, Garcia JH, Hirano A (1986) Ballooned neurons in select neurodegenerative diseases contain phosphorylated neurofilament epitopes. Acta Neuropathol 71(3\u20134):216\u2013223","journal-title":"Acta Neuropathol"},{"key":"11_CR87","first-page":"23","volume":"92","author":"JJ Rebeiz","year":"1967","unstructured":"Rebeiz JJ, Kolodny EH, Richardson EP Jr (1967) Corticodentatonigral degeneration with neuronal achromasia: a progressive disorder of late adult life. Trans Am Neurol Assoc 92:23\u201326","journal-title":"Trans Am Neurol Assoc"},{"issue":"6","key":"11_CR88","first-page":"1496","volume":"145","author":"H Ksiezak-Reding","year":"1994","unstructured":"Ksiezak-Reding H, Morgan K, Mattiace LA, Davies P, Liu WK, Yen SH et al (1994) Ultrastructure and biochemical composition of paired helical filaments in corticobasal degeneration. Am J Pathol 145(6):1496\u20131508","journal-title":"Am J Pathol"},{"issue":"2","key":"11_CR89","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1007\/BF00294503","volume":"88","author":"H Mori","year":"1994","unstructured":"Mori H, Nishimura M, Namba Y, Oda M (1994) Corticobasal degeneration: a disease with widespread appearance of abnormal tau and neurofibrillary tangles, and its relation to progressive supranuclear palsy. Acta Neuropathol 88(2):113\u2013121","journal-title":"Acta Neuropathol"},{"issue":"4","key":"11_CR90","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1007\/BF00310383","volume":"88","author":"T Uchihara","year":"1994","unstructured":"Uchihara T, Mitani K, Mori H, Kondo H, Yamada M, Ikeda K (1994) Abnormal cytoskeletal pathology peculiar to corticobasal degeneration is different from that of Alzheimer\u2019s disease or progressive supranuclear palsy. Acta Neuropathol 88(4):379\u2013383","journal-title":"Acta Neuropathol"},{"issue":"6","key":"11_CR91","first-page":"1388","volume":"146","author":"MB Feany","year":"1995","unstructured":"Feany MB, Dickson DW (1995) Widespread cytoskeletal pathology characterizes corticobasal degeneration. Am J Pathol 146(6):1388\u20131396","journal-title":"Am J Pathol"},{"issue":"Pt 11","key":"11_CR92","doi-asserted-by":"publisher","first-page":"3264","DOI":"10.1093\/brain\/awr234","volume":"134","author":"N Kouri","year":"2011","unstructured":"Kouri N, Murray ME, Hassan A, Rademakers R, Uitti RJ, Boeve BF et al (2011) Neuropathological features of corticobasal degeneration presenting as corticobasal syndrome or Richardson syndrome. Brain 134(Pt 11):3264\u20133275","journal-title":"Brain"},{"issue":"5","key":"11_CR93","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1212\/WNL.0b013e31827f0fd1","volume":"80","author":"MJ Armstrong","year":"2013","unstructured":"Armstrong MJ, Litvan I, Lang AE, Bak TH, Bhatia KP, Borroni B et al (2013) Criteria for the diagnosis of corticobasal degeneration. Neurology 80(5):496\u2013503","journal-title":"Neurology"},{"issue":"3","key":"11_CR94","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1007\/s12031-011-9624-1","volume":"45","author":"BF Boeve","year":"2011","unstructured":"Boeve BF (2011) The multiple phenotypes of corticobasal syndrome and corticobasal degeneration: implications for further study. J Mol Neuro: MN 45(3):350\u2013353","journal-title":"J Mol Neuro: MN"},{"issue":"2","key":"11_CR95","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1002\/ana.22424","volume":"70","author":"SE Lee","year":"2011","unstructured":"Lee SE, Rabinovici GD, Mayo MC, Wilson SM, Seeley WW, DeArmond SJ et al (2011) Clinicopathological correlations in corticobasal degeneration. Ann Neurol 70(2):327\u2013340","journal-title":"Ann Neurol"},{"issue":"4","key":"11_CR96","doi-asserted-by":"publisher","first-page":"959","DOI":"10.1212\/WNL.48.4.959","volume":"48","author":"J Schneider","year":"1997","unstructured":"Schneider J, Watts R, Gearing M, Brewer R, Mirra S (1997) Corticobasal degeneration neuropathologic and clinical heterogeneity. Neurology 48(4):959\u2013968","journal-title":"Neurology"},{"issue":"9","key":"11_CR97","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.1002\/mds.22574","volume":"24","author":"WT Hu","year":"2009","unstructured":"Hu WT, Rippon GW, Boeve BF, Knopman DS, Petersen RC, Parisi JE et al (2009) Alzheimer\u2019s disease and corticobasal degeneration presenting as corticobasal syndrome. Mov Disord: Off J Mov Disord Soc 24(9):1375\u20131379","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"11","key":"11_CR98","doi-asserted-by":"publisher","first-page":"2018","DOI":"10.1002\/mds.21055","volume":"21","author":"P Chand","year":"2006","unstructured":"Chand P, Grafman J, Dickson D, Ishizawa K, Litvan I (2006) Alzheimer\u2019s disease presenting as corticobasal syndrome. Mov Disord: Off J Mov Disord Soc 21(11):2018\u20132022","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"2","key":"11_CR99","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1136\/jnnp.64.2.184","volume":"64","author":"GK Wenning","year":"1998","unstructured":"Wenning GK, Litvan I, Jankovic J, Granata R, Mangone CA, McKee A et al (1998) Natural history and survival of 14 patients with corticobasal degeneration confirmed at postmortem examination. J Neurol Neurosurg Psychiatry 64(2):184\u2013189","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"1","key":"11_CR100","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1212\/WNL.48.1.119","volume":"48","author":"I Litvan","year":"1997","unstructured":"Litvan I, Agid Y, Goetz C, Jankovic J, Wenning GK, Brandel JP et al (1997) Accuracy of the clinical diagnosis of corticobasal degeneration: a clinicopathologic study. Neurology 48(1):119\u2013125","journal-title":"Neurology"},{"key":"11_CR101","first-page":"53","volume":"82","author":"DM Togasaki","year":"2000","unstructured":"Togasaki DM, Tanner CM (2000) Epidemiologic aspects. Adv Neurol 82:53\u201359","journal-title":"Adv Neurol"},{"issue":"4","key":"11_CR102","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1007\/s00401-004-0966-4","volume":"109","author":"K Tsuchiya","year":"2005","unstructured":"Tsuchiya K, Murayama S, Mitani K, Oda T, Arima K, Mimura M et al (2005) Constant and severe involvement of Betz cells in corticobasal degeneration is not consistent with pyramidal signs: a clinicopathological study of ten autopsy cases. Acta Neuropathol 109(4):353\u2013366","journal-title":"Acta Neuropathol"},{"issue":"1","key":"11_CR103","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1111\/j.1474-7766.2004.06-189.x","volume":"4","author":"KA Josephs","year":"2004","unstructured":"Josephs KA, Rossor MN (2004) The alien limb. Pract Neurol 4(1):44\u201345","journal-title":"Pract Neurol"},{"issue":"9","key":"11_CR104","doi-asserted-by":"publisher","first-page":"1969","DOI":"10.1212\/WNL.53.9.1969","volume":"53","author":"DA Grimes","year":"1999","unstructured":"Grimes DA, Lang AE, Bergeron CB (1999) Dementia as the most common presentation of cortical-basal ganglionic degeneration. Neurology 53(9):1969\u20131974","journal-title":"Neurology"},{"issue":"7","key":"11_CR105","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1001\/archneur.55.7.957","volume":"55","author":"K Kompoliti","year":"1998","unstructured":"Kompoliti K, Goetz C, Boeve BF, Maraganore D, Ahlskog J, Marsden C et al (1998) Clinical presentation and pharmacological therapy in corticobasal degeneration. Arch Neurol 55(7):957\u2013961","journal-title":"Arch Neurol"},{"issue":"S5","key":"11_CR106","doi-asserted-by":"publisher","first-page":"S15","DOI":"10.1002\/ana.10570","volume":"54","author":"BF Boeve","year":"2003","unstructured":"Boeve BF, Lang AE, Litvan I (2003) Corticobasal degeneration and its relationship to progressive supranuclear palsy and frontotemporal dementia. Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc 54(S5):S15\u2013SS9","journal-title":"Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc"},{"issue":"16","key":"11_CR107","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.1212\/01.wnl.0000259519.78480.c3","volume":"68","author":"R Murray","year":"2007","unstructured":"Murray R, Neumann M, Forman M, Farmer J, Massimo L, Rice A et al (2007) Cognitive and motor assessment in autopsy-proven corticobasal degeneration. Neurology 68(16):1274\u20131283","journal-title":"Neurology"},{"issue":"2","key":"11_CR108","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1006\/brcg.1999.1085","volume":"40","author":"DH Jacobs","year":"1999","unstructured":"Jacobs DH, Adair JC, Macauley B, Gold M, Rothi LJG, Heilman KM (1999) Apraxia in corticobasal degeneration. Brain Cogn 40(2):336\u2013354","journal-title":"Brain Cogn"},{"issue":"3","key":"11_CR109","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1007\/s11940-009-0021-9","volume":"11","author":"SG Reich","year":"2009","unstructured":"Reich SG, Grill SE (2009) Corticobasal degeneration. Curr Treat Options Neurol 11(3):179","journal-title":"Curr Treat Options Neurol"},{"key":"11_CR110","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1016\/j.neuropsychologia.2014.09.030","volume":"64","author":"N Spotorno","year":"2014","unstructured":"Spotorno N, McMillan CT, Powers JP, Clark R, Grossman M (2014) Counting or chunking? Mathematical and heuristic abilities in patients with corticobasal syndrome and posterior cortical atrophy. Neuropsychologia 64:176\u2013183","journal-title":"Neuropsychologia"},{"issue":"Pt 6","key":"11_CR111","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.1093\/brain\/awl078","volume":"129","author":"KA Josephs","year":"2006","unstructured":"Josephs KA, Duffy JR, Strand EA, Whitwell JL, Layton KF, Parisi JE et al (2006) Clinicopathological and imaging correlates of progressive aphasia and apraxia of speech. Brain 129(Pt 6):1385\u20131398","journal-title":"Brain"},{"issue":"4","key":"11_CR112","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1002\/ana.21610","volume":"65","author":"LM Shaw","year":"2009","unstructured":"Shaw LM, Vanderstichele H, Knapik-Czajka M, Clark CM, Aisen PS, Petersen RC et al (2009) Cerebrospinal fluid biomarker signature in Alzheimer\u2019s disease neuroimaging initiative subjects. Ann Neurol 65(4):403\u2013413","journal-title":"Ann Neurol"},{"key":"11_CR113","unstructured":"Ling H, Gelpi E, Davey K, Jaunmuktane Z, Mok KY, Jabbari E et al Fulminant corticobasal degeneration: a distinct variant with predominant neuronal tau aggregates. Acta Neuropathol:1\u201318"},{"issue":"12","key":"11_CR114","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.1212\/WNL.0000000000002491","volume":"86","author":"F Rodriguez-Porcel","year":"2016","unstructured":"Rodriguez-Porcel F, Lowder L, Rademakers R, Ravenscroft T, Ghetti B, Hagen MC et al (2016) Fulminant corticobasal degeneration: Agrypnia excitata in corticobasal syndrome. Neurology 86(12):1164\u20131166","journal-title":"Neurology"},{"issue":"5","key":"11_CR115","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1002\/mds.26512","volume":"31","author":"I Litvan","year":"2016","unstructured":"Litvan I, Lees PS, Cunningham CR, Rai SN, Cambon AC, Standaert DG et al (2016) Environmental and occupational risk factors for progressive supranuclear palsy: case-control study. Mov Disord 31(5):644\u2013652","journal-title":"Mov Disord"},{"key":"11_CR116","doi-asserted-by":"publisher","first-page":"474","DOI":"10.3389\/fneur.2018.00474","volume":"9","author":"KD Kelley","year":"2018","unstructured":"Kelley KD, Checkoway H, Hall DA, Reich SG, Cunningham C, Litvan I (2018) Traumatic brain injury and firearm use and risk of progressive supranuclear palsy among veterans. Front Neurol 9:474","journal-title":"Front Neurol"},{"issue":"15","key":"11_CR117","doi-asserted-by":"publisher","first-page":"1293","DOI":"10.1212\/WNL.0000000000001997","volume":"85","author":"D Caparros-Lefebvre","year":"2015","unstructured":"Caparros-Lefebvre D, Golbe LI, Deramecourt V, Maurage CA, Huin V, Buee-Scherrer V et al (2015) A geographical cluster of progressive supranuclear palsy in northern France. Neurology 85(15):1293\u20131300","journal-title":"Neurology"},{"issue":"Pt 4","key":"11_CR118","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1093\/brain\/awf086","volume":"125","author":"D Caparros-Lefebvre","year":"2002","unstructured":"Caparros-Lefebvre D, Sergeant N, Lees A, Camuzat A, Daniel S, Lannuzel A et al (2002) Guadeloupean parkinsonism: a cluster of progressive supranuclear palsy-like tauopathy. Brain 125(Pt 4):801\u2013811","journal-title":"Brain"},{"issue":"15","key":"11_CR119","doi-asserted-by":"publisher","first-page":"2122","DOI":"10.1002\/mds.22300","volume":"23","author":"A Lannuzel","year":"2008","unstructured":"Lannuzel A, Ruberg M, Michel PP (2008) Atypical parkinsonism in the Caribbean island of Guadeloupe: etiological role of the mitochondrial complex I inhibitor annonacin. Mov Disord: Off J Mov Disord Soc 23(15):2122\u20132128","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"3","key":"11_CR120","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1002\/mds.27336","volume":"33","author":"HK Park","year":"2018","unstructured":"Park HK, Ilango S, Charriez CM, Checkoway H, Riley D, Standaert DG et al (2018) Lifetime exposure to estrogen and progressive supranuclear palsy: environmental and genetic PSP study. Mov Disord 33(3):468\u2013472","journal-title":"Mov Disord"},{"key":"11_CR121","doi-asserted-by":"publisher","first-page":"7247","DOI":"10.1038\/ncomms8247","volume":"6","author":"N Kouri","year":"2015","unstructured":"Kouri N, Ross OA, Dombroski B, Younkin CS, Serie DJ, Soto-Ortolaza A et al (2015) Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy. Nat Commun 6:7247","journal-title":"Nat Commun"},{"issue":"3","key":"11_CR122","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1159\/000319454","volume":"8","author":"JD Rohrer","year":"2011","unstructured":"Rohrer JD, Paviour D, Vandrovcova J, Hodges J, De Silva R, Rossor MN (2011) Novel L284R MAPT mutation in a family with an autosomal dominant progressive supranuclear palsy syndrome. Neurodegener Dis 8(3):149\u2013152","journal-title":"Neurodegener Dis"},{"issue":"1","key":"11_CR123","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.parkreldis.2012.06.019","volume":"19","author":"K Ogaki","year":"2013","unstructured":"Ogaki K, Li Y, Takanashi M, Ishikawa K-I, Kobayashi T, Nonaka T et al (2013) Analyses of the MAPT, PGRN, and C9orf72 mutations in Japanese patients with FTLD, PSP, and CBS. Parkinsonism Relat Disord 19(1):15\u201320","journal-title":"Parkinsonism Relat Disord"},{"issue":"4","key":"11_CR124","doi-asserted-by":"publisher","DOI":"10.1212\/NXG.0000000000000347","volume":"5","author":"S Ahmed","year":"2019","unstructured":"Ahmed S, Fairen MD, Sabir MS, Pastor P, Ding J, Ispierto L et al (2019) MAPT p.V363I mutation: a rare cause of corticobasal degeneration. Neurology Genetics 5(4):e347","journal-title":"Neurology Genetics"},{"issue":"4","key":"11_CR125","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1001\/archneur.65.4.460","volume":"65","author":"BF Boeve","year":"2008","unstructured":"Boeve BF, Hutton M (2008) Refining frontotemporal dementia with parkinsonism linked to chromosome 17: introducing FTDP-17 (MAPT) and FTDP-17 (PGRN). Arch Neurol 65(4):460\u2013464","journal-title":"Arch Neurol"},{"issue":"4","key":"11_CR126","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1093\/hmg\/8.4.711","volume":"8","author":"M Baker","year":"1999","unstructured":"Baker M, Litvan I, Houlden H, Adamson J, Dickson D, Perez-Tur J et al (1999) Association of an extended haplotype in the tau gene with progressive supranuclear palsy. Hum Mol Genet 8(4):711\u2013715","journal-title":"Hum Mol Genet"},{"issue":"12","key":"11_CR127","doi-asserted-by":"publisher","first-page":"1702","DOI":"10.1212\/WNL.56.12.1702","volume":"56","author":"H Houlden","year":"2001","unstructured":"Houlden H, Baker M, Morris H, MacDonald N (2001) Pickering\u2013Brown S, Adamson J, et al. Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype. Neurology 56(12):1702\u20131706","journal-title":"Neurology"},{"issue":"7","key":"11_CR128","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1038\/ng.859","volume":"43","author":"GU H\u00f6glinger","year":"2011","unstructured":"H\u00f6glinger GU, Melhem NM, Dickson DW, Sleiman PM, Wang L-S, Klei L et al (2011) Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. Nat Genet 43(7):699","journal-title":"Nat Genet"},{"issue":"5","key":"11_CR129","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1007\/s00401-017-1693-y","volume":"133","author":"JS Yokoyama","year":"2017","unstructured":"Yokoyama JS, Karch CM, Fan CC, Bonham LW, Kouri N, Ross OA et al (2017) Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia. Acta Neuropathol 133(5):825\u2013837","journal-title":"Acta Neuropathol"},{"issue":"9","key":"11_CR130","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1034\/j.1600-0854.2001.20903.x","volume":"2","author":"F Wendler","year":"2001","unstructured":"Wendler F, Tooze S (2001) Syntaxin 6: the promiscuous behaviour of a SNARE protein. Traffic 2(9):606\u2013611","journal-title":"Traffic"},{"issue":"5","key":"11_CR131","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1016\/S1097-2765(00)80330-5","volume":"5","author":"HP Harding","year":"2000","unstructured":"Harding HP, Zhang Y, Bertolotti A, Zeng H, Ron D (2000) Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell 5(5):897\u2013904","journal-title":"Mol Cell"},{"issue":"22","key":"11_CR132","first-page":"3951","volume":"27","author":"SH Yuan","year":"2018","unstructured":"Yuan SH, Hiramatsu N, Liu Q, Sun XV, Lenh D, Chan P et al (2018) Tauopathy-associated PERK alleles are functional hypomorphs that increase neuronal vulnerability to ER stress. Hum Mol Genet 27(22):3951\u20133963","journal-title":"Hum Mol Genet"},{"issue":"1","key":"11_CR133","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-018-0267-3","volume":"13","author":"MY Sanchez-Contreras","year":"2018","unstructured":"Sanchez-Contreras MY, Kouri N, Cook CN, Serie DJ, Heckman MG, Finch NA et al (2018) Replication of progressive supranuclear palsy genome-wide association study identifies SLCO1A2 and DUSP10 as new susceptibility loci. Mol Neurodegener 13(1):37","journal-title":"Mol Neurodegener"},{"issue":"2","key":"11_CR134","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1046\/j.1471-4159.1999.0730881.x","volume":"73","author":"DS Albers","year":"1999","unstructured":"Albers DS, Augood SJ, Martin DM, Standaert DG, Vonsattel JPG, Beal MF (1999) Evidence for oxidative stress in the subthalamic nucleus in progressive supranuclear palsy. J Neurochem 73(2):881\u2013884","journal-title":"J Neurochem"},{"issue":"2","key":"11_CR135","doi-asserted-by":"publisher","first-page":"878","DOI":"10.1046\/j.1471-4159.2000.740878.x","volume":"74","author":"DS Albers","year":"2000","unstructured":"Albers DS, Augood SJ, Park LC, Browne SE, Martin DM, Adamson J et al (2000) Frontal lobe dysfunction in progressive supranuclear palsy: evidence for oxidative stress and mitochondrial impairment. J Neurochem 74(2):878\u2013881","journal-title":"J Neurochem"},{"issue":"1","key":"11_CR136","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1006\/exnr.2000.7607","volume":"168","author":"DS Albers","year":"2001","unstructured":"Albers DS, Swerdlow RH, Manfredi G, Gajewski C, Yang L, Parker WD Jr et al (2001) Further evidence for mitochondrial dysfunction in progressive supranuclear palsy. Exp Neurol 168(1):196\u2013198","journal-title":"Exp Neurol"},{"issue":"5","key":"11_CR137","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.1002\/jnr.10062","volume":"66","author":"LC Park","year":"2001","unstructured":"Park LC, Albers DS, Xu H, Lindsay JG, Beal MF, Gibson GE (2001) Mitochondrial impairment in the cerebellum of the patients with progressive supranuclear palsy. J Neurosci Res 66(5):1028\u20131034","journal-title":"J Neurosci Res"},{"issue":"6","key":"11_CR138","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1016\/S0197-0186(01)00126-7","volume":"40","author":"DS Albers","year":"2002","unstructured":"Albers DS, Beal MF (2002) Mitochondrial dysfunction in progressive supranuclear palsy. Neurochem Int 40(6):559\u2013564","journal-title":"Neurochem Int"},{"issue":"1\u20132","key":"11_CR139","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/S0006-8993(02)02244-8","volume":"930","author":"I Cantuti-Castelvetri","year":"2002","unstructured":"Cantuti-Castelvetri I, Keller-McGandy CE, Albers DS, Beal MF, Vonsattel J-P, Standaert DG et al (2002) Expression and activity of antioxidants in the brain in progressive supranuclear palsy. Brain Res 930(1\u20132):170\u2013181","journal-title":"Brain Res"},{"issue":"5","key":"11_CR140","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1002\/1531-8257(200009)15:5<889::AID-MDS1020>3.0.CO;2-T","volume":"15","author":"P Martinelli","year":"2000","unstructured":"Martinelli P, Scaglione C, Lodi R, Iotti S, Barbiroli B (2000) Deficit of brain and skeletal muscle bioenergetics in progressive supranuclear palsy shown in vivo by phosphorus magnetic resonance spectroscopy. Mov Disord 15(5):889\u2013893","journal-title":"Mov Disord"},{"issue":"9","key":"11_CR141","doi-asserted-by":"publisher","first-page":"683","DOI":"10.1016\/j.parkreldis.2011.06.007","volume":"17","author":"R Fernandez-Botran","year":"2011","unstructured":"Fernandez-Botran R, Ahmed Z, Crespo FA, Gatenbee C, Gonzalez J, Dickson DW et al (2011) Cytokine expression and microglial activation in progressive supranuclear palsy. Parkinsonism Relat Disord 17(9):683\u2013688","journal-title":"Parkinsonism Relat Disord"},{"issue":"1","key":"11_CR142","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-018-1339-6","volume":"15","author":"C Starhof","year":"2018","unstructured":"Starhof C, Winge K, Heegaard NHH, Skogstrand K, Friis S, Hejl A (2018) Cerebrospinal fluid pro-inflammatory cytokines differentiate parkinsonian syndromes. J Neuroinflammation 15(1):305","journal-title":"J Neuroinflammation"},{"issue":"3","key":"11_CR143","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1002\/ana.410360305","volume":"36","author":"J Sian","year":"1994","unstructured":"Sian J, Dexter DT, Lees AJ, Daniel S, Agid Y, Javoy-Agid F et al (1994) Alterations in glutathione levels in Parkinson\u2019s disease and other neurodegenerative disorders affecting basal ganglia. Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc 36(3):348\u2013355","journal-title":"Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc"},{"issue":"3","key":"11_CR144","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.1523\/JNEUROSCI.2642-12.2013","volume":"33","author":"M Iba","year":"2013","unstructured":"Iba M, Guo JL, McBride JD, Zhang B, Trojanowski JQ, Lee VM-Y (2013) Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer\u2019s-like tauopathy. J Neurosci 33(3):1024\u20131037","journal-title":"J Neurosci"},{"issue":"3","key":"11_CR145","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1111\/bpa.12044","volume":"23","author":"F Clavaguera","year":"2013","unstructured":"Clavaguera F, Lavenir I, Falcon B, Frank S, Goedert M, Tolnay M (2013) \u201cPrion-like\u201d templated misfolding in tauopathies. Brain Pathol 23(3):342\u2013349","journal-title":"Brain Pathol"},{"issue":"23","key":"11_CR146","doi-asserted-by":"publisher","first-page":"9535","DOI":"10.1073\/pnas.1301175110","volume":"110","author":"F Clavaguera","year":"2013","unstructured":"Clavaguera F, Akatsu H, Fraser G, Crowther RA, Frank S, Hench J et al (2013) Brain homogenates from human tauopathies induce tau inclusions in mouse brain. Proc Natl Acad Sci 110(23):9535\u20139540","journal-title":"Proc Natl Acad Sci"},{"issue":"6","key":"11_CR147","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1016\/j.neuron.2014.04.047","volume":"82","author":"DW Sanders","year":"2014","unstructured":"Sanders DW, Kaufman SK, DeVos SL, Sharma AM, Mirbaha H, Li A et al (2014) Distinct tau prion strains propagate in cells and mice and define different tauopathies. Neuron 82(6):1271\u20131288","journal-title":"Neuron"},{"issue":"5","key":"11_CR148","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1007\/s004010051148","volume":"99","author":"A Probst","year":"2000","unstructured":"Probst A, G\u00f6tz J, Wiederhold K, Tolnay M, Mistl C, Jaton A et al (2000) Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein. Acta Neuropathol 99(5):469\u2013481","journal-title":"Acta Neuropathol"},{"issue":"11","key":"11_CR149","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.1007\/s00415-004-0549-2","volume":"251","author":"K Dujardin","year":"2004","unstructured":"Dujardin K, Defebvre L, Duhamel A, Lecouffe P, Rogelet P, Steinling M et al (2004) Cognitive and SPECT characteristics predict progression of Parkinson\u2019s disease in newly diagnosed patients. J Neurol 251(11):1383\u20131392","journal-title":"J Neurol"},{"issue":"2","key":"11_CR150","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1007\/s00401-013-1231-5","volume":"127","author":"F Clavaguera","year":"2014","unstructured":"Clavaguera F, Hench J, Lavenir I, Schweighauser G, Frank S, Goedert M et al (2014) Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice. Acta Neuropathol 127(2):299\u2013301","journal-title":"Acta Neuropathol"},{"issue":"1\u20132","key":"11_CR151","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/0304-3940(92)90227-X","volume":"143","author":"M Nishimura","year":"1992","unstructured":"Nishimura M, Namba Y, Ikeda K, Oda M (1992) Glial fibrillary tangles with straight tubules in the brains of patients with progressive supranuclear palsy. Neurosci Lett 143(1\u20132):35\u201338","journal-title":"Neurosci Lett"},{"issue":"1","key":"11_CR152","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/0304-3940(92)90145-W","volume":"135","author":"T Yamada","year":"1992","unstructured":"Yamada T, McGeer P, McGeer E (1992) Appearance of paired nucleated, tau-positive glia in patients with progressive supranuclear palsy brain tissue. Neurosci Lett 135(1):99\u2013102","journal-title":"Neurosci Lett"},{"issue":"1\u20132","key":"11_CR153","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/S0022-510X(03)00014-5","volume":"210","author":"N Kato","year":"2003","unstructured":"Kato N, Arai K, Hattori T (2003) Study of the rostral midbrain atrophy in progressive supranuclear palsy. J Neurol Sci 210(1\u20132):57\u201360","journal-title":"J Neurol Sci"},{"issue":"3","key":"11_CR154","doi-asserted-by":"publisher","first-page":"125","DOI":"10.2463\/mrms.3.125","volume":"3","author":"M Adachi","year":"2004","unstructured":"Adachi M, KAWANAMI T, OHSHIMA H, Sugai Y, Hosoya T (2004) Morning glory sign: a particular MR finding in progressive supranuclear palsy. Magn Reson Med Sci 3(3):125\u2013132","journal-title":"Magn Reson Med Sci"},{"issue":"14","key":"11_CR155","doi-asserted-by":"publisher","first-page":"1754","DOI":"10.1002\/mds.24968","volume":"27","author":"LA Massey","year":"2012","unstructured":"Massey LA, Micallef C, Paviour DC, O\u2019sullivan SS, Ling H, Williams DR et al (2012) Conventional magnetic resonance imaging in confirmed progressive supranuclear palsy and multiple system atrophy. Mov Disord 27(14):1754\u20131762","journal-title":"Mov Disord"},{"issue":"14","key":"11_CR156","doi-asserted-by":"publisher","first-page":"1754","DOI":"10.1002\/mds.24968","volume":"27","author":"LA Massey","year":"2012","unstructured":"Massey LA, Micallef C, Paviour DC, O\u2019Sullivan SS, Ling H, Williams DR et al (2012) Conventional magnetic resonance imaging in confirmed progressive supranuclear palsy and multiple system atrophy. Mov Disord: Off J Mov Disord Soc 27(14):1754\u20131762","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"10","key":"11_CR157","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1111\/ene.12212","volume":"20","author":"JL Whitwell","year":"2013","unstructured":"Whitwell JL, Jack CR Jr, Parisi JE, Gunter JL, Weigand SD, Boeve BF et al (2013) Midbrain atrophy is not a biomarker of progressive supranuclear palsy pathology. Eur J Neurol 20(10):1417\u20131422","journal-title":"Eur J Neurol"},{"issue":"20","key":"11_CR158","doi-asserted-by":"publisher","first-page":"1856","DOI":"10.1212\/WNL.0b013e318292a2d2","volume":"80","author":"LA Massey","year":"2013","unstructured":"Massey LA, Jager HR, Paviour DC, O\u2019Sullivan SS, Ling H, Williams DR et al (2013) The midbrain to pons ratio: a simple and specific MRI sign of progressive supranuclear palsy. Neurology 80(20):1856\u20131861","journal-title":"Neurology"},{"issue":"1","key":"11_CR159","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1148\/radiol.2453061703","volume":"246","author":"A Quattrone","year":"2008","unstructured":"Quattrone A, Nicoletti G, Messina D, Fera F, Condino F, Pugliese P et al (2008) MR imaging index for differentiation of progressive supranuclear palsy from Parkinson disease and the Parkinson variant of multiple system atrophy. Radiology 246(1):214\u2013221","journal-title":"Radiology"},{"issue":"5","key":"11_CR160","doi-asserted-by":"publisher","first-page":"778","DOI":"10.1002\/mds.26921","volume":"32","author":"L Moller","year":"2017","unstructured":"Moller L, Kassubek J, Sudmeyer M, Hilker R, Hattingen E, Egger K et al (2017) Manual MRI morphometry in parkinsonian syndromes. Mov Disord: Off J Mov Disord Soc 32(5):778\u2013782","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"6","key":"11_CR161","doi-asserted-by":"publisher","first-page":"2665","DOI":"10.1007\/s00330-016-4622-x","volume":"27","author":"S Nigro","year":"2017","unstructured":"Nigro S, Arabia G, Antonini A, Weis L, Marcante A, Tessitore A et al (2017) Magnetic Resonance Parkinsonism Index: diagnostic accuracy of a fully automated algorithm in comparison with the manual measurement in a large Italian multicentre study in patients with progressive supranuclear palsy. Eur Radiol 27(6):2665\u20132675","journal-title":"Eur Radiol"},{"key":"11_CR162","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1016\/j.nicl.2016.05.016","volume":"11","author":"S Zanigni","year":"2016","unstructured":"Zanigni S, Calandra-Buonaura G, Manners DN, Testa C, Gibertoni D, Evangelisti S et al (2016) Accuracy of MR markers for differentiating Progressive Supranuclear Palsy from Parkinson\u2019s disease. NeuroImage Clinical 11:736\u2013742","journal-title":"NeuroImage Clinical"},{"issue":"14","key":"11_CR163","doi-asserted-by":"publisher","first-page":"2444","DOI":"10.1002\/mds.23351","volume":"25","author":"A Hussl","year":"2010","unstructured":"Hussl A, Mahlknecht P, Scherfler C, Esterhammer R, Schocke M, Poewe W et al (2010) Diagnostic accuracy of the magnetic resonance Parkinsonism index and the midbrain-to-pontine area ratio to differentiate progressive supranuclear palsy from Parkinson\u2019s disease and the Parkinson variant of multiple system atrophy. Mov Disord: Off J Mov Disord Soc 25(14):2444\u20132449","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"6","key":"11_CR164","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1001\/archneurol.2011.107","volume":"68","author":"JL Whitwell","year":"2011","unstructured":"Whitwell JL, Master AV, Avula R, Kantarci K, Eggers SD, Edmonson HA et al (2011) Clinical correlates of white matter tract degeneration in progressive supranuclear palsy. Arch Neurol 68(6):753\u2013760","journal-title":"Arch Neurol"},{"issue":"8","key":"11_CR165","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1016\/j.parkreldis.2011.05.013","volume":"17","author":"JL Whitwell","year":"2011","unstructured":"Whitwell JL, Avula R, Master A, Vemuri P, Senjem ML, Jones DT et al (2011) Disrupted thalamocortical connectivity in PSP: a resting-state fMRI, DTI, and VBM study. Parkinsonism Relat Disord 17(8):599\u2013605","journal-title":"Parkinsonism Relat Disord"},{"issue":"5","key":"11_CR166","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1002\/ana.23844","volume":"73","author":"RC Gardner","year":"2013","unstructured":"Gardner RC, Boxer AL, Trujillo A, Mirsky JB, Guo CC, Gennatas ED et al (2013) Intrinsic connectivity network disruption in progressive supranuclear palsy. Ann Neurol 73(5):603\u2013616","journal-title":"Ann Neurol"},{"issue":"2","key":"11_CR167","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1016\/j.neurobiolaging.2006.09.019","volume":"29","author":"KA Josephs","year":"2008","unstructured":"Josephs KA, Whitwell JL, Dickson DW, Boeve BF, Knopman DS, Petersen RC et al (2008) Voxel-based morphometry in autopsy proven PSP and CBD. Neurobiol Aging 29(2):280\u2013289","journal-title":"Neurobiol Aging"},{"issue":"2","key":"11_CR168","doi-asserted-by":"publisher","first-page":"714","DOI":"10.1016\/j.neuroimage.2003.09.070","volume":"21","author":"K Gr\u00f6schel","year":"2004","unstructured":"Gr\u00f6schel K, Hauser T-K, Luft A, Patronas N, Dichgans J, Litvan I et al (2004) Magnetic resonance imaging-based volumetry differentiates progressive supranuclear palsy from corticobasal degeneration. NeuroImage 21(2):714\u2013724","journal-title":"NeuroImage"},{"issue":"4","key":"11_CR169","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1111\/jon199664222","volume":"6","author":"RA Hauser","year":"1996","unstructured":"Hauser RA, Murtaugh FR, Akhter K, Gold M, Olanow C (1996) Magnetic resonance imaging of corticobasal degeneration. J Neuroimaging 6(4):222\u2013226","journal-title":"J Neuroimaging"},{"issue":"11","key":"11_CR170","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1007\/s00234-007-0265-6","volume":"49","author":"M Koyama","year":"2007","unstructured":"Koyama M, Yagishita A, Nakata Y, Hayashi M, Bandoh M, Mizutani T (2007) Imaging of corticobasal degeneration syndrome. Neuroradiology 49(11):905\u2013912","journal-title":"Neuroradiology"},{"issue":"1","key":"11_CR171","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1001\/archneur.63.1.81","volume":"63","author":"AL Boxer","year":"2006","unstructured":"Boxer AL, Geschwind MD, Belfor N, Gorno-Tempini ML, Schauer GF, Miller BL et al (2006) Patterns of brain atrophy that differentiate corticobasal degeneration syndrome from progressive supranuclear palsy. Arch Neurol 63(1):81\u201386","journal-title":"Arch Neurol"},{"issue":"12","key":"11_CR172","doi-asserted-by":"publisher","first-page":"1881","DOI":"10.1001\/archneur.61.12.1881","volume":"61","author":"KA Josephs","year":"2004","unstructured":"Josephs KA, Tang-Wai DF, Edland SD, Knopman DS, Dickson DW, Parisi JE et al (2004) Correlation between antemortem magnetic resonance imaging findings and pathologically confirmed corticobasal degeneration. Arch Neurol 61(12):1881\u20131884","journal-title":"Arch Neurol"},{"issue":"3","key":"11_CR173","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/j.parkreldis.2009.11.013","volume":"16","author":"A Hassan","year":"2010","unstructured":"Hassan A, Whitwell JL, Boeve BF, Jack CR Jr, Parisi JE, Dickson DW et al (2010) Symmetric corticobasal degeneration (S-CBD). Parkinsonism Relat Disord 16(3):208\u2013214","journal-title":"Parkinsonism Relat Disord"},{"issue":"9","key":"11_CR174","doi-asserted-by":"publisher","first-page":"1246","DOI":"10.1002\/mds.23062","volume":"25","author":"KA Josephs","year":"2010","unstructured":"Josephs KA, Whitwell JL, Boeve BF, Knopman DS, Petersen RC, Hu WT et al (2010) Anatomical differences between CBS-corticobasal degeneration and CBS-Alzheimer\u2019s disease. Mov Disord: Off J Mov Disord Soc 25(9):1246\u20131252","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"21","key":"11_CR175","doi-asserted-by":"publisher","first-page":"1879","DOI":"10.1212\/WNL.0b013e3181feb2e8","volume":"75","author":"JL Whitwell","year":"2010","unstructured":"Whitwell JL, Jack CR Jr, Boeve BF, Parisi JE, Ahlskog JE, Drubach DA et al (2010) Imaging correlates of pathology in corticobasal syndrome. Neurology 75(21):1879\u20131887","journal-title":"Neurology"},{"issue":"12","key":"11_CR176","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.1212\/WNL.0000000000003119","volume":"87","author":"CT McMillan","year":"2016","unstructured":"McMillan CT, Boyd C, Gross RG, Weinstein J, Firn K, Toledo JB et al (2016) Multimodal imaging evidence of pathology-mediated disease distribution in corticobasal syndrome. Neurology 87(12):1227\u20131234","journal-title":"Neurology"},{"issue":"3","key":"11_CR177","doi-asserted-by":"publisher","DOI":"10.1007\/s12031-011-9533-3","volume":"45","author":"JL Whitwell","year":"2011","unstructured":"Whitwell JL, Jack CR, Parisi JE, Knopman DS, Boeve BF, Petersen RC et al (2011) Imaging signatures of molecular pathology in behavioral variant frontotemporal dementia. J Mol Neurosci 45(3):372","journal-title":"J Mol Neurosci"},{"issue":"3","key":"11_CR178","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1038\/nrneurol.2012.7","volume":"8","author":"JL Whitwell","year":"2011","unstructured":"Whitwell JL, Josephs KA (2011) Neuroimaging in frontotemporal lobar degeneration--predicting molecular pathology. Nat Rev Neurol 8(3):131\u2013142","journal-title":"Nat Rev Neurol"},{"issue":"9","key":"11_CR179","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1136\/jnnp-2012-304418","volume":"84","author":"CT McMillan","year":"2013","unstructured":"McMillan CT, Irwin DJ, Avants BB, Powers J, Cook PA, Toledo JB et al (2013) White matter imaging helps dissociate tau from TDP-43 in frontotemporal lobar degeneration. J Neurol Neurosurg Psychiatry 84(9):949\u2013955","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"2","key":"11_CR180","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1016\/j.parkreldis.2013.10.023","volume":"20","author":"H Botha","year":"2014","unstructured":"Botha H, Whitwell JL, Madhaven A, Senjem ML, Lowe V, Josephs KA (2014) The pimple sign of progressive supranuclear palsy syndrome. Parkinsonism Relat Disord 20(2):180\u2013185","journal-title":"Parkinsonism Relat Disord"},{"issue":"4","key":"11_CR181","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1007\/s00415-014-7256-4","volume":"261","author":"N Zalewski","year":"2014","unstructured":"Zalewski N, Botha H, Whitwell JL, Lowe V, Dickson DW, Josephs KA (2014) FDG-PET in pathologically confirmed spontaneous 4R-tauopathy variants. J Neurol 261(4):710\u2013716","journal-title":"J Neurol"},{"issue":"1","key":"11_CR182","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/S1474-4422(14)70252-2","volume":"14","author":"VL Villemagne","year":"2015","unstructured":"Villemagne VL, Fodero-Tavoletti MT, Masters CL, Rowe CC (2015) Tau imaging: early progress and future directions. Lancet Neurol 14(1):114\u2013124","journal-title":"Lancet Neurol"},{"issue":"5","key":"11_CR183","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1002\/ana.24517","volume":"78","author":"M Marqui\u00e9","year":"2015","unstructured":"Marqui\u00e9 M, Normandin MD, Vanderburg CR, Costantino IM, Bien EA, Rycyna LG et al (2015) Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue. Ann Neurol 78(5):787\u2013800","journal-title":"Ann Neurol"},{"issue":"3","key":"11_CR184","first-page":"781","volume":"140","author":"L Passamonti","year":"2017","unstructured":"Passamonti L, Vazquez Rodriguez P, Hong YT, Allinson KS, Williamson D, Borchert RJ et al (2017) 18F-AV-1451 positron emission tomography in Alzheimer\u2019s disease and progressive supranuclear palsy. Brain 140(3):781\u2013791","journal-title":"Brain"},{"issue":"3","key":"11_CR185","first-page":"748","volume":"140","author":"MJ Pontecorvo","year":"2017","unstructured":"Pontecorvo MJ, Devous Sr MD, Navitsky M, Lu M, Salloway S, Schaerf FW et al (2017) Relationships between flortaucipir PET tau binding and amyloid burden, clinical diagnosis, age and cognition. Brain 140(3):748\u2013763","journal-title":"Brain"},{"issue":"2","key":"11_CR186","doi-asserted-by":"publisher","first-page":"299","DOI":"10.2967\/jnumed.117.194282","volume":"59","author":"IM Nasrallah","year":"2018","unstructured":"Nasrallah IM, Chen YJ, Hsieh M-K, Phillips JS, Ternes K, Stockbower GE et al (2018) 18F-Flortaucipir PET\/MRI correlations in nonamnestic and amnestic variants of Alzheimer disease. J Nucl Med 59(2):299\u2013306","journal-title":"J Nucl Med"},{"issue":"5","key":"11_CR187","doi-asserted-by":"publisher","first-page":"1551","DOI":"10.1093\/brain\/aww027","volume":"139","author":"R Ossenkoppele","year":"2016","unstructured":"Ossenkoppele R, Schonhaut DR, Sch\u00f6ll M, Lockhart SN, Ayakta N, Baker SL et al (2016) Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer\u2019s disease. Brain 139(5):1551\u20131567","journal-title":"Brain"},{"issue":"1","key":"11_CR188","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-016-0315-6","volume":"4","author":"VJ Lowe","year":"2016","unstructured":"Lowe VJ, Curran G, Fang P, Liesinger AM, Josephs KA, Parisi JE et al (2016) An autoradiographic evaluation of AV-1451 tau PET in dementia. Acta Neuropathol Commun 4(1):58","journal-title":"Acta Neuropathol Commun"},{"issue":"12","key":"11_CR189","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1002\/acn3.366","volume":"3","author":"WR Bevan Jones","year":"2016","unstructured":"Bevan Jones WR, Cope TE, Passamonti L, Fryer TD, Hong YT, Aigbirhio F et al (2016) [18F]AV-1451 PET in behavioral variant frontotemporal dementia due to MAPT mutation. Ann Clin Trans Neurol 3(12):940\u2013947","journal-title":"Ann Clin Trans Neurol"},{"issue":"1","key":"11_CR190","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1002\/mds.26844","volume":"32","author":"H Cho","year":"2017","unstructured":"Cho H, Choi JY, Hwang MS, Lee SH, Ryu YH, Lee MS et al (2017) Subcortical 18 F-AV-1451 binding patterns in progressive supranuclear palsy. Mov Disord: Off J Mov Disord Soc 32(1):134\u2013140","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"1","key":"11_CR191","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1002\/mds.26813","volume":"32","author":"R Smith","year":"2017","unstructured":"Smith R, Schain M, Nilsson C, Strandberg O, Olsson T, Hagerstrom D et al (2017) Increased basal ganglia binding of 18 F-AV-1451 in patients with progressive supranuclear palsy. Mov Disord: Off J Mov Disord Soc 32(1):108\u2013114","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"1","key":"11_CR192","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1002\/mds.26834","volume":"32","author":"JL Whitwell","year":"2017","unstructured":"Whitwell JL, Lowe VJ, Tosakulwong N, Weigand SD, Senjem ML, Schwarz CG et al (2017) [18 F]AV-1451 tau positron emission tomography in progressive supranuclear palsy. Mov Disord: Off J Mov Disord Soc 32(1):124\u2013133","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"key":"11_CR193","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2019.102152","volume":"25","author":"JL Whitwell","year":"2020","unstructured":"Whitwell JL, Tosakulwong N, Botha H, Ali F, Clark HM, Duffy JR et al (2020) Brain volume and flortaucipir analysis of progressive supranuclear palsy clinical variants. NeuroImage: Clinical 25:102152","journal-title":"NeuroImage: Clinical"},{"issue":"6","key":"11_CR194","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1007\/s00401-016-1640-3","volume":"132","author":"CT McMillan","year":"2016","unstructured":"McMillan CT, Irwin DJ, Nasrallah I, Phillips JS, Spindler M, Rascovsky K et al (2016) Multimodal evaluation demonstrates in vivo (18)F-AV-1451 uptake in autopsy-confirmed corticobasal degeneration. Acta Neuropathol 132(6):935\u2013937","journal-title":"Acta Neuropathol"},{"issue":"5","key":"11_CR195","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1007\/s00415-018-8815-x","volume":"265","author":"F Ali","year":"2018","unstructured":"Ali F, Whitwell JL, Martin PR, Senjem ML, Knopman DS, Jack CR et al (2018) [(18)F] AV-1451 uptake in corticobasal syndrome: the influence of beta-amyloid and clinical presentation. J Neurol 265(5):1079\u20131088","journal-title":"J Neurol"},{"issue":"1","key":"11_CR196","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1002\/mds.20668","volume":"21","author":"A Gerhard","year":"2006","unstructured":"Gerhard A, Trender-Gerhard I, Turkheimer F, Quinn NP, Bhatia KP, Brooks DJ (2006) In vivo imaging of microglial activation with [11C](R)-PK11195 PET in progressive supranuclear palsy. Mov Disord: Off J Mov Disord Soc 21(1):89\u201393","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"10","key":"11_CR197","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.1002\/mds.20162","volume":"19","author":"A Gerhard","year":"2004","unstructured":"Gerhard A, Watts J, Trender-Gerhard I, Turkheimer F, Banati RB, Bhatia K et al (2004) In vivo imaging of microglial activation with [11C](R)-PK11195 PET in corticobasal degeneration. Mov Disord: Off J Mov Disord Soc 19(10):1221\u20131226","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"2","key":"11_CR198","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1007\/s004010000283","volume":"101","author":"T Arai","year":"2001","unstructured":"Arai T, Ikeda K, Akiyama H, Shikamoto Y, Tsuchiya K, Yagishita S et al (2001) Distinct isoforms of tau aggregated in neurons and glial cells in brains of patients with Pick\u2019s disease, corticobasal degeneration and progressive supranuclear palsy. Acta Neuropathol 101(2):167\u2013173","journal-title":"Acta Neuropathol"},{"issue":"1","key":"11_CR199","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/S0022-510X(00)00480-9","volume":"183","author":"K Urakami","year":"2001","unstructured":"Urakami K, Wada K, Arai H, Sasaki H, Kanai M, Shoji M et al (2001) Diagnostic significance of tau protein in cerebrospinal fluid from patients with corticobasal degeneration or progressive supranuclear palsy. J Neurol Sci 183(1):95\u201398","journal-title":"J Neurol Sci"},{"issue":"11","key":"11_CR200","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.1001\/archneurol.2012.1654","volume":"69","author":"S Hall","year":"2012","unstructured":"Hall S, \u00d6hrfelt A, Constantinescu R, Andreasson U, Surova Y, Bostrom F et al (2012) Accuracy of a panel of 5 cerebrospinal fluid biomarkers in the differential diagnosis of patients with dementia and\/or parkinsonian disorders. Arch Neurol 69(11):1445\u20131452","journal-title":"Arch Neurol"},{"issue":"22","key":"11_CR201","doi-asserted-by":"publisher","first-page":"1796","DOI":"10.1212\/01.wnl.0000335941.68602.39","volume":"71","author":"B Borroni","year":"2008","unstructured":"Borroni B, Malinverno M, Gardoni F, Alberici A, Parnetti L, Premi E et al (2008) Tau forms in CSF as a reliable biomarker for progressive supranuclear palsy. Neurology 71(22):1796\u20131803","journal-title":"Neurology"},{"issue":"16","key":"11_CR202","doi-asserted-by":"publisher","first-page":"1443","DOI":"10.1212\/WNL.0b013e318210e671","volume":"76","author":"HB Kuiperij","year":"2011","unstructured":"Kuiperij HB, Borroni B, Verbeek MM, Gardoni F, Malinverno M, Padovani A et al (2011) Tau forms in CSF as a reliable biomarker for progressive supranuclear palsy. Neurology 76(16):1443","journal-title":"Neurology"},{"key":"11_CR203","doi-asserted-by":"crossref","unstructured":"Khalil M, Teunissen CE, Otto M, Piehl F, Sormani MP, Gattringer T et al (2018) Neurofilaments as biomarkers in neurological disorders. Nat Rev Neurol:1","DOI":"10.1038\/s41582-018-0058-z"},{"issue":"10","key":"11_CR204","doi-asserted-by":"publisher","first-page":"930","DOI":"10.1212\/WNL.0000000000003680","volume":"88","author":"O Hansson","year":"2017","unstructured":"Hansson O, Janelidze S, Hall S, Magdalinou N, Lees AJ, Andreasson U et al (2017) Blood-based NfL: a biomarker for differential diagnosis of parkinsonian disorder. Neurology 88(10):930\u2013937","journal-title":"Neurology"},{"issue":"1","key":"11_CR205","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1002\/mds.870130116","volume":"13","author":"B Holmberg","year":"1998","unstructured":"Holmberg B, Rosengren L, Karlsson JE, Johnels B (1998) Increased cerebrospinal fluid levels of neurofilament protein in progressive supranuclear palsy and multiple-system atrophy compared with Parkinson\u2019s disease. Mov Disord: Off J Mov Disord Soc 13(1):70\u201377","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"13","key":"11_CR206","doi-asserted-by":"publisher","first-page":"e1479","DOI":"10.1212\/WNL.0000000000007179","volume":"92","author":"TM Marques","year":"2019","unstructured":"Marques TM, van Rumund A, Oeckl P, Kuiperij HB, Esselink RA, Bloem BR et al (2019) Serum NFL discriminates Parkinson disease from atypical parkinsonisms. Neurology 92(13):e1479\u2013e1e86","journal-title":"Neurology"},{"issue":"1\u20132","key":"11_CR207","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.jns.2015.03.041","volume":"352","author":"W Sako","year":"2015","unstructured":"Sako W, Murakami N, Izumi Y, Kaji R (2015) Neurofilament light chain level in cerebrospinal fluid can differentiate Parkinson\u2019s disease from atypical parkinsonism: evidence from a meta-analysis. J Neurol Sci 352(1\u20132):84\u201387","journal-title":"J Neurol Sci"},{"issue":"3","key":"11_CR208","first-page":"216","volume":"3","author":"JC Rojas","year":"2016","unstructured":"Rojas JC, Karydas A, Bang J, Tsai RM, Blennow K, Liman V et al (2016) Plasma neurofilament light chain predicts progression in progressive supranuclear palsy. Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc 3(3):216\u2013225","journal-title":"Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc"},{"issue":"10","key":"11_CR209","doi-asserted-by":"publisher","first-page":"1655","DOI":"10.1515\/cclm-2015-1195","volume":"54","author":"J Kuhle","year":"2016","unstructured":"Kuhle J, Barro C, Andreasson U, Derfuss T, Lindberg R, Sandelius A et al (2016) Comparison of three analytical platforms for quantification of the neurofilament light chain in blood samples: ELISA, electrochemiluminescence immunoassay and Simoa. Clin Chem Lab Med 54(10):1655\u20131661","journal-title":"Clin Chem Lab Med"},{"issue":"1","key":"11_CR210","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-018-0508-2","volume":"6","author":"BR Groveman","year":"2018","unstructured":"Groveman BR, Orr\u00f9 CD, Hughson AG, Raymond LD, Zanusso G, Ghetti B et al (2018) Rapid and ultra-sensitive quantitation of disease-associated \u03b1-synuclein seeds in brain and cerebrospinal fluid by \u03b1Syn RT-QuIC. Acta Neuropathol Commun 6(1):7","journal-title":"Acta Neuropathol Commun"},{"issue":"4","key":"11_CR211","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1007\/s00401-018-1947-3","volume":"137","author":"A Kraus","year":"2019","unstructured":"Kraus A, Saijo E, Metrick MA 2nd, Newell K, Sigurdson CJ, Zanusso G et al (2019) Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease. Acta Neuropathol 137(4):585\u2013598","journal-title":"Acta Neuropathol"},{"issue":"5","key":"11_CR212","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1007\/s00401-017-1692-z","volume":"133","author":"E Saijo","year":"2017","unstructured":"Saijo E, Ghetti B, Zanusso G, Oblak A, Furman JL, Diamond MI et al (2017) Ultrasensitive and selective detection of 3-repeat tau seeding activity in Pick disease brain and cerebrospinal fluid. Acta Neuropathol 133(5):751\u2013765","journal-title":"Acta Neuropathol"},{"issue":"1","key":"11_CR213","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1007\/s00401-019-02080-2","volume":"139","author":"E Saijo","year":"2020","unstructured":"Saijo E, Metrick MA, Koga S, Parchi P, Litvan I, Spina S et al (2020) 4-repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration. Acta Neuropathol 139(1):63\u201377","journal-title":"Acta Neuropathol"},{"issue":"8","key":"11_CR214","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1212\/WNL.40.8.1203","volume":"40","author":"D Riley","year":"1990","unstructured":"Riley D, Lang A, Ae L, Resch L, Ashby P, Hornykiewicz O et al (1990) Cortical-basal ganglionic degeneration. Neurology 40(8):1203","journal-title":"Neurology"},{"issue":"3","key":"11_CR215","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1002\/ana.410130308","volume":"13","author":"JA Jackson","year":"1983","unstructured":"Jackson JA, Jankovic J, Ford J (1983) Progressive supranuclear palsy: clinical features and response to treatment in 16 patients. Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc 13(3):273\u2013278","journal-title":"Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc"},{"key":"11_CR216","doi-asserted-by":"crossref","unstructured":"Stowe R, Ives N, Clarke CE, Ferreira J, Hawker RJ, Shah L et al (2008) Dopamine agonist therapy in early Parkinson\u2019s disease. Cochrane Database Syst Rev (2):CD006564","DOI":"10.1002\/14651858.CD006564.pub2"},{"issue":"8","key":"11_CR217","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1001\/archneur.55.8.1099","volume":"55","author":"K Kompoliti","year":"1998","unstructured":"Kompoliti K, Goetz C, Litvan I, Jellinger K, Verny M (1998) Pharmacological therapy in progressive supranuclear palsy. Arch Neurol 55(8):1099\u20131102","journal-title":"Arch Neurol"},{"issue":"9","key":"11_CR218","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1111\/j.1532-5415.1996.tb02940.x","volume":"44","author":"PA Engel","year":"1996","unstructured":"Engel PA (1996) Treatment of progressive supranuclear palsy with amitriptyline: therapeutic and toxic effects. J Am Geriatr Soc 44(9):1072\u20131074","journal-title":"J Am Geriatr Soc"},{"issue":"4","key":"11_CR219","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/S1353-8020(97)00022-9","volume":"3","author":"A Rajrut","year":"1997","unstructured":"Rajrut A, Uitti R, Fenton M, George D (1997) Amantadine effectiveness in multiple system atrophy and progressive supranuclear palsy. Parkinsonism Relat Disord 3(4):211\u2013214","journal-title":"Parkinsonism Relat Disord"},{"issue":"7","key":"11_CR220","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1056\/NEJM199908123410721","volume":"341","author":"A Daniele","year":"1999","unstructured":"Daniele A, Moro E, Bentivoglio AR (1999) Zolpidem in progressive supranuclear palsy. N Engl J Med 341(7):543\u2013544","journal-title":"N Engl J Med"},{"issue":"3","key":"11_CR221","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.jocn.2009.05.038","volume":"17","author":"C Cotter","year":"2010","unstructured":"Cotter C, Armytage T, Crimmins D (2010) The use of zolpidem in the treatment of progressive supranuclear palsy. J Clin Neurosci 17(3):385\u2013386","journal-title":"J Clin Neurosci"},{"issue":"2","key":"11_CR222","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1046\/j.1468-1331.2002.0354g.x","volume":"9","author":"BJ Mayr","year":"2002","unstructured":"Mayr BJ, Bonelli RM, Niederwieser G, K\u00f6ltringer P, Reisecker F (2002) Zolpidem in progressive supranuclear palsy. Eur J Neurol 9(2):184\u2013185","journal-title":"Eur J Neurol"},{"issue":"3","key":"11_CR223","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1007\/s004150200009","volume":"249","author":"J M\u00fcller","year":"2002","unstructured":"M\u00fcller J, Wenning G, Wissel J, Seppi K, Poewe W (2002) Botulinum toxin treatment in atypical parkinsonian disorders associated with disabling focal dystonia. J Neurol 249(3):300\u2013304","journal-title":"J Neurol"},{"issue":"5","key":"11_CR224","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/S0003-9993(97)90169-6","volume":"78","author":"F Piccione","year":"1997","unstructured":"Piccione F, Mancini E, Tonin P, Bizzarini M (1997) Botulinum toxin treatment of apraxia of eyelid opening in progressive supranuclear palsy: report of two cases. Arch Phys Med Rehabil 78(5):525\u2013529","journal-title":"Arch Phys Med Rehabil"},{"issue":"2","key":"11_CR225","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1002\/mds.1038","volume":"16","author":"Z Vanek","year":"2001","unstructured":"Vanek Z, Jankovic J (2001) Dystonia in corticobasal degeneration. Mov Disord: Off J Mov Disord Soc 16(2):252\u2013257","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"2","key":"11_CR226","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1002\/ana.410350218","volume":"35","author":"KB Polo","year":"1994","unstructured":"Polo KB, Jabbari B (1994) Botulinum toxin-A improves the rigidity of progressive supranuclear palsy. Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc 35(2):237\u2013239","journal-title":"Ann Neurol: Off J Am Neurol Assoc Child Neurol Soc"},{"key":"11_CR227","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1016\/S0072-9752(07)01249-3","volume":"89","author":"BF Boeve","year":"2008","unstructured":"Boeve BF, Josephs KA, Drubach DA (2008) Current and future management of the corticobasal syndrome and corticobasal degeneration. Handb Clin Neurol 89:533\u2013548","journal-title":"Handb Clin Neurol"},{"issue":"12","key":"11_CR228","doi-asserted-by":"publisher","first-page":"1631","DOI":"10.1007\/s00702-009-0301-2","volume":"116","author":"T Kov\u00e1cs","year":"2009","unstructured":"Kov\u00e1cs T, Farsang M, Vitaszil E, Barsi P, Gy\u00f6rke T, Szirmai I et al (2009) Levetiracetam reduces myoclonus in corticobasal degeneration: report of two cases. J Neural Transm 116(12):1631","journal-title":"J Neural Transm"},{"issue":"2","key":"11_CR229","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1007\/s10072-014-1950-y","volume":"36","author":"MT G\u00f3mez-Caravaca","year":"2015","unstructured":"G\u00f3mez-Caravaca MT, C\u00e1ceres-Redondo MT, Huertas-Fern\u00e1ndez I, Vargas-Gonz\u00e1lez L, Carrillo F, Carballo M et al (2015) The use of botulinum toxin in the treatment of sialorrhea in parkinsonian disorders. Neurol Sci 36(2):275\u2013279","journal-title":"Neurol Sci"},{"issue":"6","key":"11_CR230","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1002\/mds.10276","volume":"17","author":"HC Hyson","year":"2002","unstructured":"Hyson HC, Johnson AM, Jog MS (2002) Sublingual atropine for sialorrhea secondary to parkinsonism: a pilot study. Mov Disord: Off J Mov Disord Soc 17(6):1318\u20131320","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"3","key":"11_CR231","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1212\/WNL.57.3.467","volume":"57","author":"I Litvan","year":"2001","unstructured":"Litvan I, Phipps M, Pharr VL, Hallett M, Grafman J, Salazar A (2001) Randomized placebo-controlled trial of donepezil in patients with progressive supranuclear palsy. Neurology 57(3):467\u2013473","journal-title":"Neurology"},{"issue":"1","key":"11_CR232","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1097\/01.JGP.0000231744.69631.33","volume":"15","author":"MF Mendez","year":"2007","unstructured":"Mendez MF, Shapira JS, McMurtray A, Licht E (2007) Preliminary findings: behavioral worsening on donepezil in patients with frontotemporal dementia. Am J Geriatr Psychiatry 15(1):84\u201387","journal-title":"Am J Geriatr Psychiatry"},{"issue":"2","key":"11_CR233","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/S1474-4422(12)70320-4","volume":"12","author":"AL Boxer","year":"2013","unstructured":"Boxer AL, Knopman DS, Kaufer DI, Grossman M, Onyike C, Graf-Radford N et al (2013) Memantine in patients with frontotemporal lobar degeneration: a multicentre, randomised, double-blind, placebo-controlled trial. Lancet Neurol 12(2):149\u2013156","journal-title":"Lancet Neurol"},{"issue":"3","key":"11_CR234","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1097\/WAD.0b013e318197852f","volume":"23","author":"AL Boxer","year":"2009","unstructured":"Boxer AL, Lipton AM, Womack K, Merrilees J, Neuhaus J, Pavlic D et al (2009) An open label study of memantine treatment in three subtypes of frontotemporal lobar degeneration. Alzheimer Dis Assoc Disord 23(3):211","journal-title":"Alzheimer Dis Assoc Disord"},{"issue":"11","key":"11_CR235","doi-asserted-by":"publisher","first-page":"2255","DOI":"10.1185\/03007995.2014.940040","volume":"30","author":"GL Pattee","year":"2014","unstructured":"Pattee GL, Wymer JP, Lomen-Hoerth C, Appel SH, Formella AE, Pope LE (2014) An open-label multicenter study to assess the safety of dextromethorphan\/quinidine in patients with pseudobulbar affect associated with a range of underlying neurological conditions. Curr Med Res Opin 30(11):2255\u20132265","journal-title":"Curr Med Res Opin"},{"issue":"2","key":"11_CR236","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0170927","volume":"12","author":"I Clerici","year":"2017","unstructured":"Clerici I, Ferrazzoli D, Maestri R, Bossio F, Zivi I, Canesi M et al (2017) Rehabilitation in progressive supranuclear palsy: effectiveness of two multidisciplinary treatments. PLoS One 12(2):e0170927","journal-title":"PLoS One"},{"issue":"12","key":"11_CR237","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.2522\/ptj.20070302","volume":"88","author":"C Zampieri","year":"2008","unstructured":"Zampieri C, Di Fabio RP (2008) Balance and eye movement training to improve gait in people with progressive supranuclear palsy: quasi-randomized clinical trial. Phys Ther 88(12):1460\u20131473","journal-title":"Phys Ther"},{"issue":"8","key":"11_CR238","doi-asserted-by":"publisher","first-page":"1078","DOI":"10.2522\/ptj.20060166","volume":"87","author":"TM Steffen","year":"2007","unstructured":"Steffen TM, Boeve BF, Mollinger-Riemann LA, Petersen CM (2007) Long-term locomotor training for gait and balance in a patient with mixed progressive supranuclear palsy and corticobasal degeneration. Phys Ther 87(8):1078\u20131087","journal-title":"Phys Ther"},{"issue":"1\u20132","key":"11_CR239","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1155\/2013\/824302","volume":"26","author":"M Henry","year":"2013","unstructured":"Henry M, Meese M, Truong S, Babiak M, Miller B, Gorno-Tempini M (2013) Treatment for apraxia of speech in nonfluent variant primary progressive aphasia. Behav Neurol 26(1\u20132):77\u201388","journal-title":"Behav Neurol"},{"issue":"1","key":"11_CR240","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1159\/000341602","volume":"2","author":"L Farrajota","year":"2012","unstructured":"Farrajota L, Maruta C, Maroco J, Martins IP, Guerreiro M, De Mendonca A (2012) Speech therapy in primary progressive aphasia: a pilot study. Dement Geriatr Cogn Disord Extra 2(1):321\u2013331","journal-title":"Dement Geriatr Cogn Disord Extra"},{"key":"11_CR241","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.parkreldis.2016.10.013","volume":"34","author":"L Wiblin","year":"2017","unstructured":"Wiblin L, Lee M, Burn D (2017) Palliative care and its emerging role in multiple system atrophy and progressive supranuclear palsy. Parkinsonism Relat Disord 34:7\u201314","journal-title":"Parkinsonism Relat Disord"},{"issue":"1","key":"11_CR242","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/S0165-0173(00)00019-9","volume":"33","author":"L Bu\u00e9e","year":"2000","unstructured":"Bu\u00e9e L, Bussi\u00e8re T, Bu\u00e9e-Scherrer V, Delacourte A, Hof PR (2000) Tau protein isoforms, phosphorylation and role in neurodegenerative disorders. Brain Res Rev 33(1):95\u2013130","journal-title":"Brain Res Rev"},{"key":"11_CR243","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.clineuro.2016.04.021","volume":"146","author":"L Leclair-Visonneau","year":"2016","unstructured":"Leclair-Visonneau L, Rouaud T, Debilly B, Durif F, Houeto JL, Kreisler A et al (2016) Randomized placebo-controlled trial of sodium valproate in progressive supranuclear palsy. Clin Neurol Neurosurg 146:35\u201339","journal-title":"Clin Neurol Neurosurg"},{"issue":"10","key":"11_CR244","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1038\/nm.3951","volume":"21","author":"S-W Min","year":"2015","unstructured":"Min S-W, Chen X, Tracy TE, Li Y, Zhou Y, Wang C et al (2015) Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Nat Med 21(10):1154","journal-title":"Nat Med"},{"issue":"4","key":"11_CR245","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1038\/nchembio.797","volume":"8","author":"SA Yuzwa","year":"2012","unstructured":"Yuzwa SA, Shan X, Macauley MS, Clark T, Skorobogatko Y, Vosseller K et al (2012) Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation. Nat Chem Biol 8(4):393\u2013399","journal-title":"Nat Chem Biol"},{"issue":"52","key":"11_CR246","doi-asserted-by":"publisher","first-page":"15120","DOI":"10.1073\/pnas.1606899113","volume":"113","author":"AC Wang","year":"2016","unstructured":"Wang AC, Jensen EH, Rexach JE, Vinters HV, Hsieh-Wilson LC (2016) Loss of O-GlcNAc glycosylation in forebrain excitatory neurons induces neurodegeneration. Proc Natl Acad Sci U S A 113(52):15120\u201315125","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"7","key":"11_CR247","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1016\/S1474-4422(14)70088-2","volume":"13","author":"AL Boxer","year":"2014","unstructured":"Boxer AL, Lang AE, Grossman M, Knopman DS, Miller BL, Schneider LS et al (2014) Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2\/3 trial. Lancet Neurol 13(7):676\u2013685","journal-title":"Lancet Neurol"},{"key":"11_CR248","unstructured":"Boxer AMZ, Tsai R, Koestler M, Rojas J, Ljubenkov P, Rosen H et al (2017) A phase 1B, randomized, double-blind, placebo-controlled, sequential cohort, dose-ranging study of the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of TPI 287 (abeotaxane) in patients with primary four repeat tauopathies: corticobasal syndrome or progressive supranuclear palsy; or the secondary tauopathy, Alzheimer\u2019s disease. J Prev Alz Dis 4(4):282\u2013428"},{"issue":"11","key":"11_CR249","doi-asserted-by":"publisher","first-page":"3601","DOI":"10.1523\/JNEUROSCI.4922-11.2012","volume":"32","author":"B Zhang","year":"2012","unstructured":"Zhang B, Carroll J, Trojanowski JQ, Yao Y, Iba M, Potuzak JS et al (2012) The microtubule-stabilizing agent, epothilone D, reduces axonal dysfunction, neurotoxicity, cognitive deficits, and Alzheimer-like pathology in an interventional study with aged tau transgenic mice. J Neurosci Off J Soc Neurosci 32(11):3601\u20133611","journal-title":"J Neurosci Off J Soc Neurosci"},{"issue":"2","key":"11_CR250","doi-asserted-by":"publisher","first-page":"705","DOI":"10.3233\/JAD-142874","volume":"44","author":"CM Wischik","year":"2015","unstructured":"Wischik CM, Staff RT, Wischik DJ, Bentham P, Murray AD, Storey JM et al (2015) Tau aggregation inhibitor therapy: an exploratory phase 2 study in mild or moderate Alzheimer\u2019s disease. J Alzheimer\u2019s Disease: JAD 44(2):705\u2013720","journal-title":"J Alzheimer\u2019s Disease: JAD"},{"issue":"Pt 1","key":"11_CR251","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1093\/brain\/awn291","volume":"132","author":"G Bensimon","year":"2009","unstructured":"Bensimon G, Ludolph A, Agid Y, Vidailhet M, Payan C, Leigh PN (2009) Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: the NNIPPS study. Brain 132(Pt 1):156\u2013171","journal-title":"Brain"},{"issue":"5","key":"11_CR252","doi-asserted-by":"publisher","first-page":"e266","DOI":"10.1212\/NXI.0000000000000266","volume":"3","author":"D Apetauerova","year":"2016","unstructured":"Apetauerova D, Scala SA, Hamill RW, Simon DK, Pathak S, Ruthazer R et al (2016) CoQ10 in progressive supranuclear palsy: a randomized, placebo-controlled, double-blind trial. Neurology(R) Neuroimmunol Neuroinflammation 3(5):e266","journal-title":"Neurology(R) Neuroimmunol Neuroinflammation"},{"issue":"8","key":"11_CR253","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1007\/s00415-016-8169-1","volume":"263","author":"G Nuebling","year":"2016","unstructured":"Nuebling G, Hensler M, Paul S, Zwergal A, Crispin A, Lorenzl S (2016) PROSPERA: a randomized, controlled trial evaluating rasagiline in progressive supranuclear palsy. J Neurol 263(8):1565\u20131574","journal-title":"J Neurol"},{"issue":"7","key":"11_CR254","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1002\/mds.22023","volume":"23","author":"M Stamelou","year":"2008","unstructured":"Stamelou M, Reuss A, Pilatus U, Magerkurth J, Niklowitz P, Eggert KM et al (2008) Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, placebo-controlled trial. Mov Disord: Off J Mov Disord Soc 23(7):942\u2013949","journal-title":"Mov Disord: Off J Mov Disord Soc"},{"issue":"2","key":"11_CR255","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1016\/j.neurobiolaging.2014.09.007","volume":"36","author":"J Bright","year":"2015","unstructured":"Bright J, Hussain S, Dang V, Wright S, Cooper B, Byun T et al (2015) Human secreted tau increases amyloid-beta production. Neurobiol Aging 36(2):693\u2013709","journal-title":"Neurobiol Aging"},{"key":"11_CR256","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1016\/j.trci.2018.10.007","volume":"4","author":"IA Qureshi","year":"2018","unstructured":"Qureshi IA, Tirucherai G, Ahlijanian MK, Kolaitis G, Bechtold C, Grundman M (2018) A randomized, single ascending dose study of intravenous BIIB092 in healthy participants. Alzheimer\u2019s & Dement: Transl Res Clin Interv 4:746\u2013755","journal-title":"Alzheimer\u2019s & Dement: Transl Res Clin Interv"},{"issue":"6","key":"11_CR257","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1016\/S1474-4422(19)30139-5","volume":"18","author":"AL Boxer","year":"2019","unstructured":"Boxer AL, Qureshi I, Ahlijanian M, Grundman M, Golbe LI, Litvan I et al (2019) Safety of the tau-directed monoclonal antibody BIIB092 in progressive supranuclear palsy: a randomised, placebo-controlled, multiple ascending dose phase 1b trial. Lancet Neurol 18(6):549\u2013558","journal-title":"Lancet Neurol"},{"key":"11_CR258","doi-asserted-by":"crossref","unstructured":"Dam T, Boxer A, Golbe LI, H\u00f6glinger G, Morris HR, Litvan I et al (2018) Efficacy and safety of BIIB092 in patients with progressive supranuclear palsy: passport phase 2 study design (P6. 073). AAN Enterprises","DOI":"10.1212\/WNL.90.15_supplement.P6.073"},{"issue":"7","key":"11_CR259","first-page":"P599","volume":"13","author":"K Budur","year":"2017","unstructured":"Budur K, West T, Braunstein JB, Fogelman I, Bordelon YM, Litvan I et al (2017) Results of a phase 1, single ascending dose, placebo-controlled study of ABBV-8E12 in patients with progressive supranuclear palsy and phase 2 study design in early Alzheimer\u2019s disease. Alzheimers Dement 13(7):P599\u2013P600","journal-title":"Alzheimers Dement"},{"issue":"04","key":"11_CR260","first-page":"236","volume":"4","author":"T West","year":"2017","unstructured":"West T, Hu Y, Verghese P, Bateman R, Braunstein J, Fogelman I et al (2017) Preclinical and clinical development of ABBV-8E12, a humanized anti-tau antibody, for treatment of Alzheimer\u2019s disease and other tauopathies. J Prev Alzheimers Dis 4(04):236\u2013241","journal-title":"J Prev Alzheimers Dis"},{"issue":"4","key":"11_CR261","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1111\/j.1471-4159.2011.07337.x","volume":"118","author":"A Boutajangout","year":"2011","unstructured":"Boutajangout A, Ingadottir J, Davies P, Sigurdsson EM (2011) Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain. J Neurochem 118(4):658\u2013667","journal-title":"J Neurochem"},{"issue":"39","key":"11_CR262","doi-asserted-by":"publisher","first-page":"34457","DOI":"10.1074\/jbc.M111.229633","volume":"286","author":"X Chai","year":"2011","unstructured":"Chai X, Wu S, Murray TK, Kinley R, Cella CV, Sims H et al (2011) Passive immunization with anti-Tau antibodies in two transgenic models: reduction of Tau pathology and delay of disease progression. J Biol Chem 286(39):34457\u201334467","journal-title":"J Biol Chem"},{"issue":"5","key":"11_CR263","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0125614","volume":"10","author":"S Sankaranarayanan","year":"2015","unstructured":"Sankaranarayanan S, Barten DM, Vana L, Devidze N, Yang L, Cadelina G et al (2015) Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models. PLoS One 10(5):e0125614","journal-title":"PLoS One"},{"issue":"1","key":"11_CR264","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1111\/jnc.12821","volume":"132","author":"A Ittner","year":"2015","unstructured":"Ittner A, Bertz J, Suh LS, Stevens CH, Gotz J, Ittner LM (2015) Tau-targeting passive immunization modulates aspects of pathology in tau transgenic mice. J Neurochem 132(1):135\u2013145","journal-title":"J Neurochem"},{"issue":"s1","key":"11_CR265","doi-asserted-by":"publisher","first-page":"S97","DOI":"10.3233\/JAD-132477","volume":"40","author":"DL Castillo-Carranza","year":"2014","unstructured":"Castillo-Carranza DL, Gerson JE, Sengupta U, Guerrero-Mu\u00f1oz MJ, Lasagna-Reeves CA, Kayed R (2014) Specific targeting of tau oligomers in htau mice prevents cognitive impairment and tau toxicity following injection with brain-derived tau oligomeric seeds. J Alzheimers Dis 40(s1):S97\u2013S111","journal-title":"J Alzheimers Dis"},{"key":"11_CR266","doi-asserted-by":"publisher","DOI":"10.1038\/srep00700","volume":"2","author":"CA Lasagna-Reeves","year":"2012","unstructured":"Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Guerrero-Munoz MJ, Kiritoshi T, Neugebauer V et al (2012) Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau. Sci Rep 2:700","journal-title":"Sci Rep"},{"issue":"3","key":"11_CR267","doi-asserted-by":"publisher","first-page":"243","DOI":"10.4161\/mabs.3.3.15234","volume":"3","author":"T Igawa","year":"2011","unstructured":"Igawa T, Tsunoda H, Kuramochi T, Sampei Z, Ishii S, Hattori K (2011) Engineering the variable region of therapeutic IgG antibodies. MAbs 3(3):243\u2013252","journal-title":"MAbs"},{"issue":"5","key":"11_CR268","doi-asserted-by":"publisher","first-page":"343","DOI":"10.2174\/156652321405140926160602","volume":"14","author":"H Xu","year":"2014","unstructured":"Xu H, Rosler TW, Carlsson T, de Andrade A, Fiala O, Hollerhage M et al (2014) Tau silencing by siRNA in the P301S mouse model of tauopathy. Curr Gene Ther 14(5):343\u2013351","journal-title":"Curr Gene Ther"},{"key":"11_CR269","doi-asserted-by":"publisher","DOI":"10.1038\/mtna.2014.30","volume":"3","author":"R Sud","year":"2014","unstructured":"Sud R, Geller ET, Schellenberg GD (2014) Antisense-mediated exon skipping decreases tau protein expression: a potential therapy for tauopathies. Mol Ther Nucleic Acids 3:e180","journal-title":"Mol Ther Nucleic Acids"},{"issue":"5","key":"11_CR270","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1016\/j.neuron.2016.04.042","volume":"90","author":"KM Schoch","year":"2016","unstructured":"Schoch KM, DeVos SL, Miller RL, Chun SJ, Norrbom M, Wozniak DF et al (2016) Increased 4R-tau induces pathological changes in a human-tau mouse model. Neuron 90(5):941\u2013947","journal-title":"Neuron"}],"container-title":["Advances in Experimental Medicine and Biology","Frontotemporal Dementias"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-030-51140-1_11","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T07:20:45Z","timestamp":1724311245000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-030-51140-1_11"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"ISBN":["9783030511395","9783030511401"],"references-count":270,"URL":"https:\/\/doi.org\/10.1007\/978-3-030-51140-1_11","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"13 January 2021","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}