{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T05:44:47Z","timestamp":1780379087882,"version":"3.54.1"},"publisher-location":"Cham","reference-count":360,"publisher":"Springer International Publishing","isbn-type":[{"value":"9783030573614","type":"print"},{"value":"9783030573621","type":"electronic"}],"license":[{"start":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T00:00:00Z","timestamp":1605657600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,11,18]],"date-time":"2020-11-18T00:00:00Z","timestamp":1605657600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021]]},"DOI":"10.1007\/978-3-030-57362-1_11","type":"book-chapter","created":{"date-parts":[[2020,11,17]],"date-time":"2020-11-17T03:02:50Z","timestamp":1605582170000},"page":"245-301","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Novel Functions and Virus\u2013Host Interactions Implicated in Pathogenesis and Replication of Human Herpesvirus 8"],"prefix":"10.1007","author":[{"given":"Young Bong","family":"Choi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Cousins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Nicholas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,11,18]]},"reference":[{"issue":"23","key":"11_CR1","doi-asserted-by":"publisher","first-page":"12139","DOI":"10.1128\/JVI.00884-10","volume":"84","author":"JR Abend","year":"2010","unstructured":"Abend JR, Uldrick T, Ziegelbauer JM (2010) Regulation of tumor necrosis factor-like weak inducer of apoptosis receptor protein (TWEAKR) expression by Kaposi\u2019s sarcoma-associated herpesvirus microRNA prevents TWEAK-induced apoptosis and inflammatory cytokine expression. J Virol 84(23):12139\u201312151. https:\/\/doi.org\/10.1128\/JVI.00884-10","journal-title":"J Virol"},{"issue":"21","key":"11_CR2","doi-asserted-by":"publisher","first-page":"11663","DOI":"10.1128\/JVI.01147-12","volume":"86","author":"JR Abend","year":"2012","unstructured":"Abend JR, Ramalingam D, Kieffer-Kwon P, Uldrick TS, Yarchoan R, Ziegelbauer JM (2012) Kaposi\u2019s sarcoma-associated herpesvirus microRNAs target IRAK1 and MYD88, two components of the toll-like receptor\/interleukin-1R signaling cascade, to reduce inflammatory-cytokine expression. J Virol 86(21):11663\u201311674. https:\/\/doi.org\/10.1128\/JVI.01147-12","journal-title":"J Virol"},{"key":"11_CR3","doi-asserted-by":"publisher","unstructured":"Abere B, Samarina N, Gramolelli S, Ruckert J, Gerold G, Pich A et al (2018) Kaposi\u2019s sarcoma-associated herpesvirus nonstructural membrane protein pK15 recruits the class II phosphatidylinositol 3-Kinase PI3K-C2alpha to activate productive viral replication. J Virol 92(17). https:\/\/doi.org\/10.1128\/jvi.00544-18","DOI":"10.1128\/jvi.00544-18"},{"issue":"1","key":"11_CR4","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1016\/0042-6822(92)91247-R","volume":"190","author":"JC Albrecht","year":"1992","unstructured":"Albrecht JC, Nicholas J, Cameron KR, Newman C, Fleckenstein B, Honess RW (1992) Herpesvirus saimiri has a gene specifying a homologue of the cellular membrane glycoprotein CD59. Virology 190(1):527\u2013530","journal-title":"Virology"},{"issue":"7","key":"11_CR5","doi-asserted-by":"publisher","first-page":"3388","DOI":"10.1128\/JVI.74.7.3388-3398.2000","volume":"74","author":"L Alexander","year":"2000","unstructured":"Alexander L, Denekamp L, Knapp A, Auerbach MR, Damania B, Desrosiers RC (2000) The primary sequence of rhesus monkey rhadinovirus isolate 26-95: sequence similarities to Kaposi\u2019s sarcoma-associated herpesvirus and rhesus monkey rhadinovirus isolate 17577. J Virol 74(7):3388\u20133398","journal-title":"J Virol"},{"issue":"1\u20133","key":"11_CR6","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/S0171-2985(97)80035-6","volume":"198","author":"T Alonzi","year":"1997","unstructured":"Alonzi T, Gorgoni B, Screpanti I, Gulino A, Poli V (1997) Interleukin-6 and CAAT\/enhancer binding protein beta-deficient mice act as tools to dissect the IL-6 signalling pathway and IL-6 regulation. Immunobiology 198(1\u20133):144\u2013156","journal-title":"Immunobiology"},{"issue":"8","key":"11_CR7","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1038\/nm0897-917","volume":"3","author":"G Ambrosini","year":"1997","unstructured":"Ambrosini G, Adida C, Altieri DC (1997) A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med 3(8):917\u2013921","journal-title":"Nat Med"},{"issue":"22","key":"11_CR8","doi-asserted-by":"publisher","first-page":"3371","DOI":"10.1038\/sj.onc.1206407","volume":"22","author":"J An","year":"2003","unstructured":"An J, Sun Y, Sun R, Rettig MB (2003) Kaposi\u2019s sarcoma-associated herpesvirus encoded vFLIP induces cellular IL-6 expression: the role of the NF-kappaB and JNK\/AP1 pathways. Oncogene 22(22):3371\u20133385. https:\/\/doi.org\/10.1038\/sj.onc.1206407","journal-title":"Oncogene"},{"issue":"5","key":"11_CR9","doi-asserted-by":"publisher","first-page":"3862","DOI":"10.1074\/jbc.M407435200","volume":"280","author":"FQ An","year":"2005","unstructured":"An FQ, Compitello N, Horwitz E, Sramkoski M, Knudsen ES, Renne R (2005) The latency-associated nuclear antigen of Kaposi\u2019s sarcoma-associated herpesvirus modulates cellular gene expression and protects lymphoid cells from p16 INK4A-induced cell cycle arrest. J Biol Chem 280(5):3862\u20133874. https:\/\/doi.org\/10.1074\/jbc.M407435200","journal-title":"J Biol Chem"},{"issue":"11","key":"11_CR10","doi-asserted-by":"publisher","first-page":"e1005985","DOI":"10.1371\/journal.ppat.1005985","volume":"12","author":"PM Anders","year":"2016","unstructured":"Anders PM, Zhang Z, Bhende PM, Giffin L, Damania B (2016) The KSHV K1 protein modulates AMPK function to enhance cell survival. PLoS Pathog 12(11):e1005985. https:\/\/doi.org\/10.1371\/journal.ppat.1005985","journal-title":"PLoS Pathog"},{"issue":"43","key":"11_CR11","doi-asserted-by":"publisher","first-page":"33416","DOI":"10.1074\/jbc.M003929200","volume":"275","author":"JE Angell","year":"2000","unstructured":"Angell JE, Lindner DJ, Shapiro PS, Hofmann ER, Kalvakolanu DV (2000) Identification of GRIM-19, a novel cell death-regulatory gene induced by the interferon-beta and retinoic acid combination, using a genetic approach. J Biol Chem 275(43):33416\u201333426. https:\/\/doi.org\/10.1074\/jbc.M003929200","journal-title":"J Biol Chem"},{"issue":"12","key":"11_CR12","doi-asserted-by":"publisher","first-page":"4247","DOI":"10.1182\/blood.V94.12.4247","volume":"94","author":"Y Aoki","year":"1999","unstructured":"Aoki Y, Tosato G (1999) Role of vascular endothelial growth factor\/vascular permeability factor in the pathogenesis of Kaposi\u2019s sarcoma-associated herpesvirus-infected primary effusion lymphomas. Blood 94(12):4247\u20134254","journal-title":"Blood"},{"issue":"2","key":"11_CR13","doi-asserted-by":"publisher","first-page":"115","DOI":"10.2174\/1568005033481222","volume":"3","author":"Y Aoki","year":"2003","unstructured":"Aoki Y, Tosato G (2003) Targeted inhibition of angiogenic factors in AIDS-related disorders. Curr Drug Targets Infect Disord 3(2):115\u2013128","journal-title":"Curr Drug Targets Infect Disord"},{"issue":"12","key":"11_CR14","doi-asserted-by":"publisher","first-page":"4034","DOI":"10.1182\/blood.V93.12.4034.412k38_4034_4043","volume":"93","author":"Y Aoki","year":"1999","unstructured":"Aoki Y, Jaffe ES, Chang Y, Jones K, Teruya-Feldstein J, Moore PS et al (1999) Angiogenesis and hematopoiesis induced by Kaposi\u2019s sarcoma-associated herpesvirus-encoded interleukin-6. Blood 93(12):4034\u20134043","journal-title":"Blood"},{"issue":"4","key":"11_CR15","doi-asserted-by":"publisher","first-page":"1599","DOI":"10.1182\/blood.V96.4.1599.h8001599_1599_1601","volume":"96","author":"Y Aoki","year":"2000","unstructured":"Aoki Y, Yarchoan R, Braun J, Iwamoto A, Tosato G (2000) Viral and cellular cytokines in AIDS-related malignant lymphomatous effusions. Blood 96(4):1599\u20131601","journal-title":"Blood"},{"issue":"10","key":"11_CR16","doi-asserted-by":"publisher","first-page":"3042","DOI":"10.1182\/blood.V98.10.3042","volume":"98","author":"Y Aoki","year":"2001","unstructured":"Aoki Y, Narazaki M, Kishimoto T, Tosato G (2001) Receptor engagement by viral interleukin-6 encoded by Kaposi sarcoma-associated herpesvirus. Blood 98(10):3042\u20133049","journal-title":"Blood"},{"issue":"4","key":"11_CR17","doi-asserted-by":"publisher","first-page":"1535","DOI":"10.1182\/blood-2002-07-2130","volume":"101","author":"Y Aoki","year":"2003","unstructured":"Aoki Y, Feldman GM, Tosato G (2003) Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma. Blood 101(4):1535\u20131542. https:\/\/doi.org\/10.1182\/blood-2002-07-2130","journal-title":"Blood"},{"issue":"35","key":"11_CR18","doi-asserted-by":"publisher","first-page":"23272","DOI":"10.1074\/jbc.M109.033290","volume":"284","author":"C Areste","year":"2009","unstructured":"Areste C, Mutocheluh M, Blackbourn DJ (2009) Identification of caspase-mediated decay of interferon regulatory factor-3, exploited by a Kaposi sarcoma-associated herpesvirus immunoregulatory protein. J Biol Chem 284(35):23272\u201323285. https:\/\/doi.org\/10.1074\/jbc.M109.033290","journal-title":"J Biol Chem"},{"issue":"7","key":"11_CR19","doi-asserted-by":"publisher","first-page":"2648","DOI":"10.1182\/blood.V88.7.2648.bloodjournal8872648","volume":"88","author":"L Arvanitakis","year":"1996","unstructured":"Arvanitakis L, Mesri EA, Nador RG, Said JW, Asch AS, Knowles DM et al (1996) Establishment and characterization of a primary effusion (body cavity-based) lymphoma cell line (BC-3) harboring kaposi\u2019s sarcoma-associated herpesvirus (KSHV\/HHV-8) in the absence of Epstein-Barr virus. Blood 88(7):2648\u20132654","journal-title":"Blood"},{"issue":"6662","key":"11_CR20","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1038\/34193","volume":"391","author":"C Bais","year":"1998","unstructured":"Bais C, Santomasso B, Coso O, Arvanitakis L, Raaka EG, Gutkind JS et al (1998) G-protein-coupled receptor of Kaposi\u2019s sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator. Nature 391(6662):86\u201389. https:\/\/doi.org\/10.1038\/34193","journal-title":"Nature"},{"issue":"1","key":"11_CR21","doi-asserted-by":"publisher","first-page":"e1004581","DOI":"10.1371\/journal.ppat.1004581","volume":"11","author":"G Ballon","year":"2015","unstructured":"Ballon G, Akar G, Cesarman E (2015) Systemic expression of Kaposi sarcoma herpesvirus (KSHV) Vflip in endothelial cells leads to a profound proinflammatory phenotype and myeloid lineage remodeling in vivo. PLoS Pathog 11(1):e1004581. https:\/\/doi.org\/10.1371\/journal.ppat.1004581","journal-title":"PLoS Pathog"},{"issue":"5762","key":"11_CR22","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1126\/science.1120541","volume":"311","author":"AJ Barbera","year":"2006","unstructured":"Barbera AJ, Chodaparambil JV, Kelley-Clarke B, Joukov V, Walter JC, Luger K et al (2006) The nucleosomal surface as a docking station for Kaposi\u2019s sarcoma herpesvirus LANA. Science 311(5762):856\u2013861. https:\/\/doi.org\/10.1126\/science.1120541","journal-title":"Science"},{"issue":"20","key":"11_CR23","doi-asserted-by":"publisher","first-page":"16199","DOI":"10.1074\/jbc.M111.335216","volume":"287","author":"P Baresova","year":"2012","unstructured":"Baresova P, Pitha PM, Lubyova B (2012) Kaposi sarcoma-associated herpesvirus vIRF-3 protein binds to F-box of Skp2 protein and acts as a regulator of c-Myc protein function and stability. J Biol Chem 287(20):16199\u201316208. https:\/\/doi.org\/10.1074\/jbc.M111.335216","journal-title":"J Biol Chem"},{"issue":"3","key":"11_CR24","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1128\/MCB.01011-13","volume":"34","author":"P Baresova","year":"2014","unstructured":"Baresova P, Musilova J, Pitha PM, Lubyova B (2014) p53 tumor suppressor protein stability and transcriptional activity are targeted by Kaposi\u2019s sarcoma-associated herpesvirus-encoded viral interferon regulatory factor 3. Mol Cell Biol 34(3):386\u2013399. https:\/\/doi.org\/10.1128\/MCB.01011-13","journal-title":"Mol Cell Biol"},{"issue":"2","key":"11_CR25","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/S0092-8674(04)00045-5","volume":"116","author":"DP Bartel","year":"2004","unstructured":"Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116(2):281\u2013297","journal-title":"Cell"},{"issue":"43","key":"11_CR26","doi-asserted-by":"publisher","first-page":"33189","DOI":"10.1074\/jbc.C000318200","volume":"275","author":"M Bartoli","year":"2000","unstructured":"Bartoli M, Gu X, Tsai NT, Venema RC, Brooks SE, Marrero MB et al (2000) Vascular endothelial growth factor activates STAT proteins in aortic endothelial cells. J Biol Chem 275(43):33189\u201333192. https:\/\/doi.org\/10.1074\/jbc.C000318200","journal-title":"J Biol Chem"},{"issue":"2","key":"11_CR27","first-page":"62","volume":"4","author":"C Belanger","year":"2001","unstructured":"Belanger C, Gravel A, Tomoiu A, Janelle ME, Gosselin J, Tremblay MJ et al (2001) Human herpesvirus 8 viral FLICE-inhibitory protein inhibits Fas-mediated apoptosis through binding and prevention of procaspase-8 maturation. J Hum Virol. 4(2):62\u201373","journal-title":"J Hum Virol."},{"issue":"6","key":"11_CR28","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1016\/j.chom.2009.11.008","volume":"6","author":"P Bellare","year":"2009","unstructured":"Bellare P, Ganem D (2009) Regulation of KSHV lytic switch protein expression by a virus-encoded microRNA: an evolutionary adaptation that fine-tunes lytic reactivation. Cell Host Microbe 6(6):570\u2013575. https:\/\/doi.org\/10.1016\/j.chom.2009.11.008","journal-title":"Cell Host Microbe"},{"issue":"14","key":"11_CR29","doi-asserted-by":"publisher","first-page":"7097","DOI":"10.1128\/JVI.03390-14","volume":"89","author":"P Bellare","year":"2015","unstructured":"Bellare P, Dufresne A, Ganem D (2015) Inefficient codon usage impairs mRNA accumulation: the case of the v-FLIP gene of Kaposi\u2019s sarcoma-associated herpesvirus. J Virol 89(14):7097\u20137107. https:\/\/doi.org\/10.1128\/JVI.03390-14","journal-title":"J Virol"},{"issue":"4","key":"11_CR30","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1073\/pnas.94.4.1172","volume":"94","author":"J Bertin","year":"1997","unstructured":"Bertin J, Armstrong RC, Ottilie S, Martin DA, Wang Y, Banks S et al (1997) Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis. Proc Natl Acad Sci U S A. 94(4):1172\u20131176","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"6","key":"11_CR31","doi-asserted-by":"publisher","first-page":"a003129","DOI":"10.1101\/cshperspect.a003129","volume":"1","author":"G Berx","year":"2009","unstructured":"Berx G, van Roy F (2009) Involvement of members of the cadherin superfamily in cancer. Cold Spring Harb Perspect Biol 1(6):a003129. https:\/\/doi.org\/10.1101\/cshperspect.a003129","journal-title":"Cold Spring Harb Perspect Biol"},{"issue":"5336","key":"11_CR32","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1126\/science.278.5336.290","volume":"278","author":"C Boshoff","year":"1997","unstructured":"Boshoff C, Endo Y, Collins PD, Takeuchi Y, Reeves JD, Schweickart VL et al (1997) Angiogenic and HIV-inhibitory functions of KSHV-encoded chemokines. Science 278(5336):290\u2013294","journal-title":"Science"},{"issue":"19","key":"11_CR33","doi-asserted-by":"publisher","first-page":"9877","DOI":"10.1128\/JVI.05558-11","volume":"85","author":"IW Boss","year":"2011","unstructured":"Boss IW, Nadeau PE, Abbott JR, Yang Y, Mergia A, Renne R (2011) A Kaposi\u2019s sarcoma-associated herpesvirus-encoded ortholog of microRNA miR-155 induces human splenic B-cell expansion in NOD\/LtSz-scid IL2Rgammanull mice. J Virol 85(19):9877\u20139886. https:\/\/doi.org\/10.1128\/JVI.05558-11","journal-title":"J Virol"},{"issue":"3","key":"11_CR34","doi-asserted-by":"publisher","first-page":"e00668","DOI":"10.1128\/mBio.00668-15","volume":"6","author":"S Botto","year":"2015","unstructured":"Botto S, Totonchy JE, Gustin JK, Moses AV (2015) Kaposi sarcoma herpesvirus induces HO-1 during De Novo infection of endothelial cells via viral miRNA-dependent and -independent mechanisms. MBio. 6(3):e00668. https:\/\/doi.org\/10.1128\/mBio.00668-15","journal-title":"MBio."},{"issue":"5628","key":"11_CR35","doi-asserted-by":"publisher","first-page":"2101","DOI":"10.1126\/science.1083901","volume":"300","author":"MJ Boulanger","year":"2003","unstructured":"Boulanger MJ, Chow DC, Brevnova EE, Garcia KC (2003) Hexameric structure and assembly of the interleukin-6\/IL-6 alpha-receptor\/gp130 complex. Science 300(5628):2101\u20132104. https:\/\/doi.org\/10.1126\/science.1083901","journal-title":"Science"},{"issue":"2","key":"11_CR36","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1016\/j.jmb.2003.10.070","volume":"335","author":"MJ Boulanger","year":"2004","unstructured":"Boulanger MJ, Chow DC, Brevnova E, Martick M, Sandford G, Nicholas J et al (2004) Molecular mechanisms for viral mimicry of a human cytokine: activation of gp130 by HHV-8 interleukin-6. J Mol Biol 335(2):641\u2013654","journal-title":"J Mol Biol"},{"issue":"6495","key":"11_CR37","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1038\/371355a0","volume":"371","author":"RJ Bram","year":"1994","unstructured":"Bram RJ, Crabtree GR (1994) Calcium signalling in T cells stimulated by a cyclophilin B-binding protein. Nature 371(6495):355\u2013358. https:\/\/doi.org\/10.1038\/371355a0","journal-title":"Nature"},{"issue":"Pt 5","key":"11_CR38","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1099\/vir.0.81598-0","volume":"87","author":"MM Brinkmann","year":"2006","unstructured":"Brinkmann MM, Schulz TF (2006) Regulation of intracellular signalling by the terminal membrane proteins of members of the Gammaherpesvirinae. J Gen Virol 87(Pt 5):1047\u20131074. https:\/\/doi.org\/10.1099\/vir.0.81598-0","journal-title":"J Gen Virol"},{"issue":"17","key":"11_CR39","doi-asserted-by":"publisher","first-page":"9346","DOI":"10.1128\/JVI.77.17.9346-9358.2003","volume":"77","author":"MM Brinkmann","year":"2003","unstructured":"Brinkmann MM, Glenn M, Rainbow L, Kieser A, Henke-Gendo C, Schulz TF (2003) Activation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi\u2019s sarcoma-associated herpesvirus K15 membrane protein. J Virol 77(17):9346\u20139358","journal-title":"J Virol"},{"issue":"1","key":"11_CR40","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1128\/JVI.00648-06","volume":"81","author":"MM Brinkmann","year":"2007","unstructured":"Brinkmann MM, Pietrek M, Dittrich-Breiholz O, Kracht M, Schulz TF (2007) Modulation of host gene expression by the K15 protein of Kaposi\u2019s sarcoma-associated herpesvirus. J Virol 81(1):42\u201358. https:\/\/doi.org\/10.1128\/JVI.00648-06","journal-title":"J Virol"},{"issue":"15","key":"11_CR41","doi-asserted-by":"publisher","first-page":"8532","DOI":"10.1128\/JVI.77.15.8532-8540.2003","volume":"77","author":"HJ Brown","year":"2003","unstructured":"Brown HJ, Song MJ, Deng H, Wu TT, Cheng G, Sun R (2003) NF-kappaB inhibits gammaherpesvirus lytic replication. J Virol 77(15):8532\u20138540","journal-title":"J Virol"},{"issue":"34","key":"11_CR42","doi-asserted-by":"publisher","first-page":"4979","DOI":"10.1038\/sj.onc.1210299","volume":"26","author":"D Bubman","year":"2007","unstructured":"Bubman D, Guasparri I, Cesarman E (2007) Deregulation of c-Myc in primary effusion lymphoma by Kaposi\u2019s sarcoma herpesvirus latency-associated nuclear antigen. Oncogene 26(34):4979\u20134986. https:\/\/doi.org\/10.1038\/sj.onc.1210299","journal-title":"Oncogene"},{"issue":"1","key":"11_CR43","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/BF01757344","volume":"69","author":"R Burger","year":"1994","unstructured":"Burger R, Wendler J, Antoni K, Helm G, Kalden JR, Gramatzki M (1994) Interleukin-6 production in B-cell neoplasias and Castleman\u2019s disease: evidence for an additional paracrine loop. Ann Hematol 69(1):25\u201331","journal-title":"Ann Hematol"},{"issue":"6","key":"11_CR44","doi-asserted-by":"publisher","first-page":"1858","DOI":"10.1182\/blood.V91.6.1858","volume":"91","author":"R Burger","year":"1998","unstructured":"Burger R, Neipel F, Fleckenstein B, Savino R, Ciliberto G, Kalden JR et al (1998) Human herpesvirus type 8 interleukin-6 homologue is functionally active on human myeloma cells. Blood 91(6):1858\u20131863","journal-title":"Blood"},{"issue":"5","key":"11_CR45","doi-asserted-by":"publisher","first-page":"2345","DOI":"10.1128\/JVI.75.5.2345-2352.2001","volume":"75","author":"L Burysek","year":"2001","unstructured":"Burysek L, Pitha PM (2001) Latently expressed human herpesvirus 8-encoded interferon regulatory factor 2 inhibits double-stranded RNA-activated protein kinase. J Virol 75(5):2345\u20132352. https:\/\/doi.org\/10.1128\/JVI.75.5.2345-2352.2001","journal-title":"J Virol"},{"issue":"9","key":"11_CR46","doi-asserted-by":"publisher","first-page":"7334","DOI":"10.1128\/JVI.73.9.7334-7342.1999","volume":"73","author":"L Burysek","year":"1999","unstructured":"Burysek L, Yeow WS, Lubyova B, Kellum M, Schafer SL, Huang YQ et al (1999a) Functional analysis of human herpesvirus 8-encoded viral interferon regulatory factor 1 and its association with cellular interferon regulatory factors and p300. J Virol 73(9):7334\u20137342","journal-title":"J Virol"},{"issue":"1","key":"11_CR47","first-page":"19","volume":"2","author":"L Burysek","year":"1999","unstructured":"Burysek L, Yeow WS, Pitha PM (1999b) Unique properties of a second human herpesvirus 8-encoded interferon regulatory factor (vIRF-2). J Hum Virol. 2(1):19\u201332","journal-title":"J Hum Virol."},{"issue":"15","key":"11_CR48","doi-asserted-by":"publisher","first-page":"5570","DOI":"10.1073\/pnas.0408192102","volume":"102","author":"X Cai","year":"2005","unstructured":"Cai X, Lu S, Zhang Z, Gonzalez CM, Damania B, Cullen BR (2005) Kaposi\u2019s sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. Proc Natl Acad Sci U S A. 102(15):5570\u20135575. https:\/\/doi.org\/10.1073\/pnas.0408192102","journal-title":"Proc Natl Acad Sci U S A."},{"key":"11_CR49","first-page":"137","volume":"312","author":"M Cannon","year":"2007","unstructured":"Cannon M (2007) The KSHV and other human herpesviral G protein-coupled receptors. Curr Top Microbiol Immunol 312:137\u2013156","journal-title":"Curr Top Microbiol Immunol"},{"issue":"2","key":"11_CR50","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1038\/sj.onc.1207021","volume":"23","author":"ML Cannon","year":"2004","unstructured":"Cannon ML, Cesarman E (2004) The KSHV G protein-coupled receptor signals via multiple pathways to induce transcription factor activation in primary effusion lymphoma cells. Oncogene 23(2):514\u2013523. https:\/\/doi.org\/10.1038\/sj.onc.1207021","journal-title":"Oncogene"},{"issue":"1","key":"11_CR51","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1128\/JVI.77.1.57-67.2003","volume":"77","author":"M Cannon","year":"2003","unstructured":"Cannon M, Philpott NJ, Cesarman E (2003) The Kaposi\u2019s sarcoma-associated herpesvirus G protein-coupled receptor has broad signaling effects in primary effusion lymphoma cells. J Virol 77(1):57\u201367","journal-title":"J Virol"},{"issue":"5\u20136","key":"11_CR52","doi-asserted-by":"publisher","first-page":"447","DOI":"10.3109\/10428190009148391","volume":"36","author":"A Carbone","year":"2000","unstructured":"Carbone A, Cilia AM, Gloghini A, Capello D, Perin T, Bontempo D et al (2000) Primary effusion lymphoma cell lines harbouring human herpesvirus type-8. Leuk Lymphoma 36(5\u20136):447\u2013456. https:\/\/doi.org\/10.3109\/10428190009148391","journal-title":"Leuk Lymphoma"},{"issue":"7","key":"11_CR53","doi-asserted-by":"publisher","first-page":"2718","DOI":"10.1182\/blood-2006-03-012500","volume":"109","author":"E Caselli","year":"2007","unstructured":"Caselli E, Fiorentini S, Amici C, Di Luca D, Caruso A, Santoro MG (2007) Human herpesvirus 8 acute infection of endothelial cells induces monocyte chemoattractant protein 1-dependent capillary-like structure formation: role of the IKK\/NF-kappaB pathway. Blood 109(7):2718\u20132726. https:\/\/doi.org\/10.1182\/blood-2006-03-012500","journal-title":"Blood"},{"issue":"11","key":"11_CR54","doi-asserted-by":"publisher","first-page":"5565","DOI":"10.1128\/JVI.02723-09","volume":"84","author":"S Chandriani","year":"2010","unstructured":"Chandriani S, Ganem D (2010) Array-based transcript profiling and limiting-dilution reverse transcription-PCR analysis identify additional latent genes in Kaposi\u2019s sarcoma-associated herpesvirus. J Virol 84(11):5565\u20135573. https:\/\/doi.org\/10.1128\/JVI.02723-09","journal-title":"J Virol"},{"issue":"4","key":"11_CR55","first-page":"215","volume":"5","author":"Y Chang","year":"1996","unstructured":"Chang Y, Moore PS (1996) Kaposi\u2019s Sarcoma (KS)-associated herpesvirus and its role in KS. Infect Agents Dis 5(4):215\u2013222","journal-title":"Infect Agents Dis"},{"issue":"6590","key":"11_CR56","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1038\/382410a0","volume":"382","author":"Y Chang","year":"1996","unstructured":"Chang Y, Moore PS, Talbot SJ, Boshoff CH, Zarkowska T, Godden K et al (1996) Cyclin encoded by KS herpesvirus. Nature 382(6590):410. https:\/\/doi.org\/10.1038\/382410a0","journal-title":"Nature"},{"issue":"1","key":"11_CR57","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/S1097-2765(05)00021-3","volume":"6","author":"BN Chau","year":"2000","unstructured":"Chau BN, Cheng EH, Kerr DA, Hardwick JM (2000) Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1. Mol Cell 6(1):31\u201340","journal-title":"Mol Cell"},{"issue":"42","key":"11_CR58","doi-asserted-by":"publisher","first-page":"5738","DOI":"10.1038\/sj.onc.1202976","volume":"18","author":"PM Chaudhary","year":"1999","unstructured":"Chaudhary PM, Jasmin A, Eby MT, Hood L (1999) Modulation of the NF-kappa B pathway by virally encoded death effector domains-containing proteins. Oncogene 18(42):5738\u20135746. https:\/\/doi.org\/10.1038\/sj.onc.1202976","journal-title":"Oncogene"},{"issue":"12","key":"11_CR59","doi-asserted-by":"publisher","first-page":"6281","DOI":"10.1074\/jbc.M115.710632","volume":"291","author":"S Chavoshi","year":"2016","unstructured":"Chavoshi S, Egorova O, Lacdao IK, Farhadi S, Sheng Y, Saridakis V (2016) Identification of Kaposi Sarcoma Herpesvirus (KSHV) vIRF1 Protein as a Novel Interaction Partner of Human Deubiquitinase USP7. J Biol Chem 291(12):6281\u20136291. https:\/\/doi.org\/10.1074\/jbc.M115.710632","journal-title":"J Biol Chem"},{"issue":"19","key":"11_CR60","doi-asserted-by":"publisher","first-page":"9811","DOI":"10.1128\/JVI.00872-06","volume":"80","author":"D Chen","year":"2006","unstructured":"Chen D, Nicholas J (2006) Structural requirements for gp80 independence of human herpesvirus 8 interleukin-6 (vIL-6) and evidence for gp80 stabilization of gp130 signaling complexes induced by vIL-6. J Virol 80(19):9811\u20139821. https:\/\/doi.org\/10.1128\/JVI.00872-06","journal-title":"J Virol"},{"issue":"15","key":"11_CR61","doi-asserted-by":"publisher","first-page":"7979","DOI":"10.1128\/JVI.00375-15","volume":"89","author":"D Chen","year":"2015","unstructured":"Chen D, Nicholas J (2015) Promotion of endoplasmic reticulum-associated degradation of procathepsin D by human herpesvirus 8-encoded viral interleukin-6. J Virol 89(15):7979\u20137990. https:\/\/doi.org\/10.1128\/JVI.00375-15","journal-title":"J Virol"},{"issue":"1","key":"11_CR62","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1084\/jem.188.1.193","volume":"188","author":"S Chen","year":"1998","unstructured":"Chen S, Bacon KB, Li L, Garcia GE, Xia Y, Lo D et al (1998) In vivo inhibition of CC and CX3C chemokine-induced leukocyte infiltration and attenuation of glomerulonephritis in Wistar-Kyoto (WKY) rats by vMIP-II. J Exp Med 188(1):193\u2013198","journal-title":"J Exp Med"},{"issue":"12","key":"11_CR63","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1593\/neo.09494","volume":"11","author":"X Chen","year":"2009","unstructured":"Chen X, Cheng L, Jia X, Zeng Y, Yao S, Lv Z et al (2009a) Human immunodeficiency virus type 1 Tat accelerates Kaposi sarcoma-associated herpesvirus Kaposin A-mediated tumorigenesis of transformed fibroblasts in vitro as well as in nude and immunocompetent mice. Neoplasia. 11(12):1272\u20131284","journal-title":"Neoplasia."},{"issue":"2","key":"11_CR64","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1128\/JVI.01517-08","volume":"83","author":"D Chen","year":"2009","unstructured":"Chen D, Sandford G, Nicholas J (2009b) Intracellular signaling mechanisms and activities of human herpesvirus 8 interleukin-6. J Virol 83(2):722\u2013733. https:\/\/doi.org\/10.1128\/JVI.01517-08","journal-title":"J Virol"},{"issue":"8","key":"11_CR65","doi-asserted-by":"publisher","first-page":"3898","DOI":"10.1128\/JVI.01321-09","volume":"84","author":"W Chen","year":"2010","unstructured":"Chen W, Hilton IB, Staudt MR, Burd CE, Dittmer DP (2010) Distinct p53, p53:LANA, and LANA complexes in Kaposi\u2019s Sarcoma\u2013associated Herpesvirus Lymphomas. J Virol 84(8):3898\u20133908. https:\/\/doi.org\/10.1128\/JVI.01321-09","journal-title":"J Virol"},{"issue":"3","key":"11_CR66","doi-asserted-by":"publisher","first-page":"1577","DOI":"10.1128\/JVI.05782-11","volume":"86","author":"D Chen","year":"2012","unstructured":"Chen D, Cousins E, Sandford G, Nicholas J (2012) Human herpesvirus 8 viral interleukin-6 interacts with splice variant 2 of vitamin K epoxide reductase complex subunit 1. J Virol 86(3):1577\u20131588. https:\/\/doi.org\/10.1128\/JVI.05782-11","journal-title":"J Virol"},{"issue":"22","key":"11_CR67","doi-asserted-by":"publisher","first-page":"33363","DOI":"10.18632\/oncotarget.9221","volume":"7","author":"M Chen","year":"2016","unstructured":"Chen M, Sun F, Han L, Qu Z (2016) Kaposi\u2019s sarcoma herpesvirus (KSHV) microRNA K12-1 functions as an oncogene by activating NF-kappaB\/IL-6\/STAT3 signaling. Oncotarget. 7(22):33363\u201333373. https:\/\/doi.org\/10.18632\/oncotarget.9221","journal-title":"Oncotarget."},{"key":"11_CR68","doi-asserted-by":"publisher","unstructured":"Chen D, Xiang Q, Nicholas J (2017) Human herpesvirus 8 interleukin-6 interacts with calnexin cycle components and promotes protein folding. J Virol 91(22). https:\/\/doi.org\/10.1128\/jvi.00965-17","DOI":"10.1128\/jvi.00965-17"},{"issue":"2","key":"11_CR69","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1073\/pnas.94.2.690","volume":"94","author":"EH Cheng","year":"1997","unstructured":"Cheng EH, Nicholas J, Bellows DS, Hayward GS, Guo HG, Reitz MS et al (1997) A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak. Proc Natl Acad Sci U S A. 94(2):690\u2013694","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"13","key":"11_CR70","doi-asserted-by":"publisher","first-page":"6501","DOI":"10.1128\/JVI.02396-07","volume":"82","author":"YB Choi","year":"2008","unstructured":"Choi YB, Nicholas J (2008) Autocrine and paracrine promotion of cell survival and virus replication by human herpesvirus 8 chemokines. J Virol 82(13):6501\u20136513. https:\/\/doi.org\/10.1128\/JVI.02396-07","journal-title":"J Virol"},{"issue":"2","key":"11_CR71","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1016\/j.virol.2009.11.024","volume":"397","author":"YB Choi","year":"2010","unstructured":"Choi YB, Nicholas J (2010a) Induction of angiogenic chemokine CCL2 by human herpesvirus 8 chemokine receptor. Virology 397(2):369\u2013378. https:\/\/doi.org\/10.1016\/j.virol.2009.11.024","journal-title":"Virology"},{"issue":"8","key":"11_CR72","doi-asserted-by":"publisher","first-page":"e1001031","DOI":"10.1371\/journal.ppat.1001031","volume":"6","author":"YB Choi","year":"2010","unstructured":"Choi YB, Nicholas J (2010b) Bim nuclear translocation and inactivation by viral interferon regulatory factor. PLoS Pathog 6(8):e1001031. https:\/\/doi.org\/10.1371\/journal.ppat.1001031","journal-title":"PLoS Pathog"},{"issue":"1","key":"11_CR73","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1128\/JVI.74.1.436-446.2000","volume":"74","author":"JK Choi","year":"2000","unstructured":"Choi JK, Lee BS, Shim SN, Li M, Jung JU (2000) Identification of the novel K15 gene at the rightmost end of the Kaposi\u2019s sarcoma-associated herpesvirus genome. J Virol 74(1):436\u2013446","journal-title":"J Virol"},{"issue":"6","key":"11_CR74","doi-asserted-by":"publisher","first-page":"e1002748","DOI":"10.1371\/journal.ppat.1002748","volume":"8","author":"YB Choi","year":"2012","unstructured":"Choi YB, Sandford G, Nicholas J (2012) Human herpesvirus 8 interferon regulatory factor-mediated BH3-only protein inhibition via Bid BH3-B mimicry. PLoS Pathog 8(6):e1002748. https:\/\/doi.org\/10.1371\/journal.ppat.1002748","journal-title":"PLoS Pathog"},{"issue":"5","key":"11_CR75","doi-asserted-by":"publisher","first-page":"e1007058","DOI":"10.1371\/journal.ppat.1007058","volume":"14","author":"YB Choi","year":"2018","unstructured":"Choi YB, Choi Y, Harhaj EW (2018) Peroxisomes support human herpesvirus 8 latency by stabilizing the viral oncogenic protein vFLIP via the MAVS-TRAF complex. PLoS Pathog 14(5):e1007058. https:\/\/doi.org\/10.1371\/journal.ppat.1007058","journal-title":"PLoS Pathog"},{"issue":"5511","key":"11_CR76","doi-asserted-by":"publisher","first-page":"2150","DOI":"10.1126\/science.1058308","volume":"291","author":"D Chow","year":"2001","unstructured":"Chow D, He X, Snow AL, Rose-John S, Garcia KC (2001) Structure of an extracellular gp130 cytokine receptor signaling complex. Science 291(5511):2150\u20132155. https:\/\/doi.org\/10.1126\/science.1058308","journal-title":"Science"},{"issue":"36","key":"11_CR77","doi-asserted-by":"publisher","first-page":"12885","DOI":"10.1073\/pnas.0408577102","volume":"102","author":"P Chugh","year":"2005","unstructured":"Chugh P, Matta H, Schamus S, Zachariah S, Kumar A, Richardson JA et al (2005) Constitutive NF-kappaB activation, normal Fas-induced apoptosis, and increased incidence of lymphoma in human herpes virus 8 K13 transgenic mice. Proc Natl Acad Sci U S A. 102(36):12885\u201312890. https:\/\/doi.org\/10.1073\/pnas.0408577102","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"1\u20132","key":"11_CR78","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.imlet.2008.06.011","volume":"120","author":"M Cirone","year":"2008","unstructured":"Cirone M, Lucania G, Aleandri S, Borgia G, Trivedi P, Cuomo L et al (2008) Suppression of dendritic cell differentiation through cytokines released by Primary Effusion Lymphoma cells. Immunol Lett 120(1\u20132):37\u201341. https:\/\/doi.org\/10.1016\/j.imlet.2008.06.011","journal-title":"Immunol Lett"},{"issue":"1","key":"11_CR79","doi-asserted-by":"publisher","first-page":"e1004597","DOI":"10.1371\/journal.ppat.1004597","volume":"11","author":"JA Corcoran","year":"2015","unstructured":"Corcoran JA, Johnston BP, McCormick C (2015) Viral activation of MK2-hsp27-p115RhoGEF-RhoA signaling axis causes cytoskeletal rearrangements, p-body disruption and ARE-mRNA stabilization. PLoS Pathog 11(1):e1004597. https:\/\/doi.org\/10.1371\/journal.ppat.1004597","journal-title":"PLoS Pathog"},{"issue":"19","key":"11_CR80","doi-asserted-by":"publisher","first-page":"10816","DOI":"10.1128\/JVI.02047-13","volume":"87","author":"E Cousins","year":"2013","unstructured":"Cousins E, Nicholas J (2013) Role of human herpesvirus 8 interleukin-6-activated gp130 signal transducer in primary effusion lymphoma cell growth and viability. J Virol 87(19):10816\u201310827. https:\/\/doi.org\/10.1128\/JVI.02047-13","journal-title":"J Virol"},{"issue":"20","key":"11_CR81","doi-asserted-by":"publisher","first-page":"12167","DOI":"10.1128\/JVI.01751-14","volume":"88","author":"E Cousins","year":"2014","unstructured":"Cousins E, Gao Y, Sandford G, Nicholas J (2014) Human herpesvirus 8 viral interleukin-6 signaling through gp130 promotes virus replication in primary effusion lymphoma and endothelial cells. J Virol 88(20):12167\u201312172. https:\/\/doi.org\/10.1128\/JVI.01751-14","journal-title":"J Virol"},{"issue":"36","key":"11_CR82","doi-asserted-by":"publisher","first-page":"33805","DOI":"10.1074\/jbc.M104631200","volume":"276","author":"JP Couty","year":"2001","unstructured":"Couty JP, Geras-Raaka E, Weksler BB, Gershengorn MC (2001) Kaposi\u2019s sarcoma-associated herpesvirus G protein-coupled receptor signals through multiple pathways in endothelial cells. J Biol Chem 276(36):33805\u201333811. https:\/\/doi.org\/10.1074\/jbc.M104631200","journal-title":"J Biol Chem"},{"issue":"2\u20133","key":"11_CR83","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/S0014-5793(00)02393-0","volume":"489","author":"MP Crump","year":"2001","unstructured":"Crump MP, Elisseeva E, Gong J, Clark-Lewis I, Sykes BD (2001) Structure\/function of human herpesvirus-8 MIP-II (1-71) and the antagonist N-terminal segment (1-10). FEBS Lett 489(2\u20133):171\u2013175","journal-title":"FEBS Lett"},{"issue":"Pt 6","key":"11_CR84","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.1099\/vir.0.19015-0","volume":"84","author":"C Cunningham","year":"2003","unstructured":"Cunningham C, Barnard S, Blackbourn DJ, Davison AJ (2003) Transcription mapping of human herpesvirus 8 genes encoding viral interferon regulatory factors. J Gen Virol 84(Pt 6):1471\u20131483. https:\/\/doi.org\/10.1099\/vir.0.19015-0","journal-title":"J Gen Virol"},{"issue":"31","key":"11_CR85","doi-asserted-by":"publisher","first-page":"21569","DOI":"10.1074\/jbc.274.31.21569","volume":"274","author":"DJ Dairaghi","year":"1999","unstructured":"Dairaghi DJ, Fan RA, McMaster BE, Hanley MR, Schall TJ (1999) HHV8-encoded vMIP-I selectively engages chemokine receptor CCR8. Agonist and antagonist profiles of viral chemokines. J Biol Chem 274(31):21569\u201321574","journal-title":"J Biol Chem"},{"issue":"6","key":"11_CR86","doi-asserted-by":"publisher","first-page":"5123","DOI":"10.1128\/JVI.73.6.5123-5131.1999","volume":"73","author":"B Damania","year":"1999","unstructured":"Damania B, Li M, Choi JK, Alexander L, Jung JU, Desrosiers RC (1999) Identification of the R1 oncogene and its protein product from the rhadinovirus of rhesus monkeys. J Virol 73(6):5123\u20135131","journal-title":"J Virol"},{"issue":"9","key":"11_CR87","first-page":"2010","volume":"63","author":"DP Dittmer","year":"2003","unstructured":"Dittmer DP (2003) Transcription profile of Kaposi\u2019s sarcoma-associated herpesvirus in primary Kaposi\u2019s sarcoma lesions as determined by real-time PCR arrays. Cancer Res 63(9):2010\u20132015","journal-title":"Cancer Res"},{"issue":"7","key":"11_CR88","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1084\/jem.190.7.1025","volume":"190","author":"M Djerbi","year":"1999","unstructured":"Djerbi M, Screpanti V, Catrina AI, Bogen B, Biberfeld P, Grandien A (1999) The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors. J Exp Med 190(7):1025\u20131032","journal-title":"J Exp Med"},{"issue":"4","key":"11_CR89","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1016\/j.chom.2010.03.008","volume":"7","author":"L Dolken","year":"2010","unstructured":"Dolken L, Malterer G, Erhard F, Kothe S, Friedel CC, Suffert G et al (2010) Systematic analysis of viral and cellular microRNA targets in cells latently infected with human gamma-herpesviruses by RISC immunoprecipitation assay. Cell Host Microbe 7(4):324\u2013334. https:\/\/doi.org\/10.1016\/j.chom.2010.03.008","journal-title":"Cell Host Microbe"},{"issue":"16","key":"11_CR90","doi-asserted-by":"publisher","first-page":"11943","DOI":"10.1074\/jbc.275.16.11943","volume":"275","author":"J Domin","year":"2000","unstructured":"Domin J, Gaidarov I, Smith ME, Keen JH, Waterfield MD (2000) The class II phosphoinositide 3-kinase PI3K-C2alpha is concentrated in the trans-Golgi network and present in clathrin-coated vesicles. J Biol Chem 275(16):11943\u201311950","journal-title":"J Biol Chem"},{"issue":"4","key":"11_CR91","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1038\/sj.leu.2401371","volume":"13","author":"HG Drexler","year":"1999","unstructured":"Drexler HG, Meyer C, Gaidano G, Carbone A (1999) Constitutive cytokine production by primary effusion (body cavity-based) lymphoma-derived cell lines. Leukemia 13(4):634\u2013640","journal-title":"Leukemia"},{"issue":"3","key":"11_CR92","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1093\/emboj\/18.3.644","volume":"18","author":"M Ellis","year":"1999","unstructured":"Ellis M, Chew YP, Fallis L, Freddersdorf S, Boshoff C, Weiss RA et al (1999) Degradation of p27(Kip) cdk inhibitor triggered by Kaposi\u2019s sarcoma virus cyclin-cdk6 complex. EMBO J 18(3):644\u2013653. https:\/\/doi.org\/10.1093\/emboj\/18.3.644","journal-title":"EMBO J"},{"key":"11_CR93","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1016\/S0083-6729(08)00624-9","volume":"80","author":"HM El-Shewy","year":"2009","unstructured":"El-Shewy HM, Luttrell LM (2009) Insulin-like growth factor-2\/mannose-6 phosphate receptors. Vitam Horm 80:667\u2013697. https:\/\/doi.org\/10.1016\/S0083-6729(08)00624-9","journal-title":"Vitam Horm"},{"issue":"1","key":"11_CR94","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1016\/S1359-6101(97)00037-3","volume":"9","author":"B Ensoli","year":"1998","unstructured":"Ensoli B, Sturzl M (1998) Kaposi\u2019s sarcoma: a result of the interplay among inflammatory cytokines, angiogenic factors and viral agents. Cytokine Growth Factor Rev 9(1):63\u201383","journal-title":"Cytokine Growth Factor Rev"},{"issue":"10","key":"11_CR95","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.1016\/S0959-8049(01)00121-6","volume":"37","author":"B Ensoli","year":"2001","unstructured":"Ensoli B, Sgadari C, Barillari G, Sirianni MC, Sturzl M, Monini P (2001) Biology of Kaposi\u2019s sarcoma. Eur J Cancer 37(10):1251\u20131269","journal-title":"Eur J Cancer"},{"issue":"Pt 6","key":"11_CR96","doi-asserted-by":"publisher","first-page":"1463","DOI":"10.1099\/vir.0.19014-0","volume":"84","author":"M Esteban","year":"2003","unstructured":"Esteban M, Garcia MA, Domingo-Gil E, Arroyo J, Nombela C, Rivas C (2003) The latency protein LANA2 from Kaposi\u2019s sarcoma-associated herpesvirus inhibits apoptosis induced by dsRNA-activated protein kinase but not RNase L activation. J Gen Virol 84(Pt 6):1463\u20131470. https:\/\/doi.org\/10.1099\/vir.0.19014-0","journal-title":"J Gen Virol"},{"issue":"22","key":"11_CR97","doi-asserted-by":"publisher","first-page":"11491","DOI":"10.1128\/JVI.76.22.11491-11504.2002","volume":"76","author":"P Feng","year":"2002","unstructured":"Feng P, Park J, Lee BS, Lee SH, Bram RJ, Jung JU (2002) Kaposi\u2019s sarcoma-associated herpesvirus mitochondrial K7 protein targets a cellular calcium-modulating cyclophilin ligand to modulate intracellular calcium concentration and inhibit apoptosis. J Virol 76(22):11491\u201311504","journal-title":"J Virol"},{"issue":"9","key":"11_CR98","doi-asserted-by":"publisher","first-page":"3938","DOI":"10.1128\/MCB.24.9.3938-3948.2004","volume":"24","author":"P Feng","year":"2004","unstructured":"Feng P, Scott CW, Cho NH, Nakamura H, Chung YH, Monteiro MJ et al (2004) Kaposi\u2019s sarcoma-associated herpesvirus K7 protein targets a ubiquitin-like\/ubiquitin-associated domain-containing protein to promote protein degradation. Mol Cell Biol 24(9):3938\u20133948","journal-title":"Mol Cell Biol"},{"issue":"Pt 18","key":"11_CR99","doi-asserted-by":"publisher","first-page":"3721","DOI":"10.1242\/jcs.00691","volume":"116","author":"N Field","year":"2003","unstructured":"Field N, Low W, Daniels M, Howell S, Daviet L, Boshoff C et al (2003) KSHV vFLIP binds to IKK-gamma to activate IKK. J Cell Sci 116(Pt 18):3721\u20133728. https:\/\/doi.org\/10.1242\/jcs.00691","journal-title":"J Cell Sci"},{"issue":"6","key":"11_CR100","doi-asserted-by":"publisher","first-page":"4024","DOI":"10.4049\/jimmunol.175.6.4024","volume":"175","author":"CA Fielding","year":"2005","unstructured":"Fielding CA, McLoughlin RM, Colmont CS, Kovaleva M, Harris DA, Rose-John S et al (2005) Viral IL-6 blocks neutrophil infiltration during acute inflammation. J Immunol. 175(6):4024\u20134029","journal-title":"J Immunol."},{"issue":"3","key":"11_CR101","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1038\/sj.cdd.4402292","volume":"15","author":"AM Flanagan","year":"2008","unstructured":"Flanagan AM, Letai A (2008) BH3 domains define selective inhibitory interactions with BHRF-1 and KSHV BCL-2. Cell Death Differ 15(3):580\u2013588. https:\/\/doi.org\/10.1038\/sj.cdd.4402292","journal-title":"Cell Death Differ"},{"issue":"6764","key":"11_CR102","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1038\/47266","volume":"402","author":"J Friborg Jr","year":"1999","unstructured":"Friborg J Jr, Kong W, Hottiger MO, Nabel GJ (1999) p53 inhibition by the LANA protein of KSHV protects against cell death. Nature 402(6764):889\u2013894. https:\/\/doi.org\/10.1038\/47266","journal-title":"Nature"},{"issue":"14","key":"11_CR103","doi-asserted-by":"publisher","first-page":"8019","DOI":"10.1128\/JVI.77.14.8019-8030.2003","volume":"77","author":"M Fujimuro","year":"2003","unstructured":"Fujimuro M, Hayward SD (2003) The latency-associated nuclear antigen of Kaposi\u2019s sarcoma-associated herpesvirus manipulates the activity of glycogen synthase kinase-3beta. J Virol 77(14):8019\u20138030","journal-title":"J Virol"},{"issue":"3","key":"11_CR104","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1038\/nm829","volume":"9","author":"M Fujimuro","year":"2003","unstructured":"Fujimuro M, Wu FY, ApRhys C, Kajumbula H, Young DB, Hayward GS et al (2003) A novel viral mechanism for dysregulation of beta-catenin in Kaposi\u2019s sarcoma-associated herpesvirus latency. Nat Med 9(3):300\u2013306. https:\/\/doi.org\/10.1038\/nm829","journal-title":"Nat Med"},{"issue":"6","key":"11_CR105","doi-asserted-by":"publisher","first-page":"3092","DOI":"10.1128\/JVI.80.6.3092-3097.2006","volume":"80","author":"S Fuld","year":"2006","unstructured":"Fuld S, Cunningham C, Klucher K, Davison AJ, Blackbourn DJ (2006) Inhibition of interferon signaling by the Kaposi\u2019s sarcoma-associated herpesvirus full-length viral interferon regulatory factor 2 protein. J Virol 80(6):3092\u20133097. https:\/\/doi.org\/10.1128\/JVI.80.6.3092-3097.2006","journal-title":"J Virol"},{"issue":"3\u20134","key":"11_CR106","doi-asserted-by":"publisher","first-page":"257","DOI":"10.3109\/10428199709039013","volume":"24","author":"G Gaidano","year":"1997","unstructured":"Gaidano G, Pastore C, Gloghini A, Volpe G, Capello D, Polito P et al (1997) Human herpesvirus type-8 (HHV-8) in haematopoietic neoplasia. Leuk Lymphoma 24(3\u20134):257\u2013266. https:\/\/doi.org\/10.3109\/10428199709039013","journal-title":"Leuk Lymphoma"},{"key":"11_CR107","doi-asserted-by":"publisher","unstructured":"Gallo A, Lampe M, Gunther T, Brune W (2017) The viral Bcl-2 homologs of Kaposi\u2019s sarcoma-associated herpesvirus and rhesus rhadinovirus share an essential role for viral replication. J Virol 91(6). https:\/\/doi.org\/10.1128\/jvi.01875-16","DOI":"10.1128\/jvi.01875-16"},{"key":"11_CR108","doi-asserted-by":"publisher","unstructured":"Garrigues HJ, Howard K, Barcy S, Ikoma M, Moses AV, Deutsch GH et al (2017) Full-length isoforms of Kaposi\u2019s sarcoma-associated herpesvirus latency-associated nuclear antigen accumulate in the cytoplasm of cells undergoing the lytic cycle of replication. J Virol 91(24). https:\/\/doi.org\/10.1128\/jvi.01532-17","DOI":"10.1128\/jvi.01532-17"},{"key":"11_CR109","doi-asserted-by":"publisher","unstructured":"Gay LA, Sethuraman S, Thomas M, Turner PC, Renne R (2018) Modified cross-linking, ligation, and sequencing of hybrids (qCLASH) identifies Kaposi\u2019s sarcoma-associated herpesvirus MicroRNA targets in endothelial cells. J Virol 92(8). https:\/\/doi.org\/10.1128\/jvi.02138-17","DOI":"10.1128\/jvi.02138-17"},{"issue":"10","key":"11_CR110","doi-asserted-by":"publisher","first-page":"5298","DOI":"10.1128\/JVI.00098-15","volume":"89","author":"A Gelgor","year":"2015","unstructured":"Gelgor A, Kalt I, Bergson S, Brulois KF, Jung JU, Sarid R (2015) Viral Bcl-2 encoded by the Kaposi\u2019s sarcoma-associated herpesvirus is vital for virus reactivation. J Virol 89(10):5298\u20135307. https:\/\/doi.org\/10.1128\/JVI.00098-15","journal-title":"J Virol"},{"issue":"1","key":"11_CR111","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1084\/jem.191.1.129","volume":"191","author":"R Glas","year":"2000","unstructured":"Glas R, Franksson L, Une C, Eloranta ML, Ohlen C, Orn A et al (2000) Recruitment and activation of natural killer (NK) cells in vivo determined by the target cell phenotype. An adaptive component of NK cell-mediated responses. J Exp Med 191(1):129\u2013138","journal-title":"J Exp Med"},{"issue":"8","key":"11_CR112","doi-asserted-by":"publisher","first-page":"6953","DOI":"10.1128\/JVI.73.8.6953-6963.1999","volume":"73","author":"M Glenn","year":"1999","unstructured":"Glenn M, Rainbow L, Aurade F, Davison A, Schulz TF (1999) Identification of a spliced gene from Kaposi\u2019s sarcoma-associated herpesvirus encoding a protein with similarities to latent membrane proteins 1 and 2A of Epstein-Barr virus. J Virol 73(8):6953\u20136963","journal-title":"J Virol"},{"issue":"6","key":"11_CR113","doi-asserted-by":"publisher","first-page":"2510","DOI":"10.1182\/blood-2004-08-3052","volume":"105","author":"A Godfrey","year":"2005","unstructured":"Godfrey A, Anderson J, Papanastasiou A, Takeuchi Y, Boshoff C (2005) Inhibiting primary effusion lymphoma by lentiviral vectors encoding short hairpin RNA. Blood 105(6):2510\u20132518. https:\/\/doi.org\/10.1182\/blood-2004-08-3052","journal-title":"Blood"},{"issue":"14","key":"11_CR114","doi-asserted-by":"publisher","first-page":"1903","DOI":"10.1097\/QAD.0000000000001567","volume":"31","author":"PH Goncalves","year":"2017","unstructured":"Goncalves PH, Uldrick TS, Yarchoan R (2017a) HIV-associated Kaposi sarcoma and related diseases. AIDS. 31(14):1903\u20131916. https:\/\/doi.org\/10.1097\/QAD.0000000000001567","journal-title":"AIDS."},{"issue":"1","key":"11_CR115","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1097\/COH.0000000000000330","volume":"12","author":"PH Goncalves","year":"2017","unstructured":"Goncalves PH, Ziegelbauer J, Uldrick TS, Yarchoan R (2017b) Kaposi sarcoma herpesvirus-associated cancers and related diseases. Curr Opin HIV AIDS. 12(1):47\u201356. https:\/\/doi.org\/10.1097\/COH.0000000000000330","journal-title":"Curr Opin HIV AIDS."},{"issue":"18","key":"11_CR116","doi-asserted-by":"publisher","first-page":"5016","DOI":"10.1158\/1078-0432.CCR-12-3510","volume":"19","author":"R Gopalakrishnan","year":"2013","unstructured":"Gopalakrishnan R, Matta H, Chaudhary PM (2013) A purine scaffold HSP90 inhibitor BIIB021 has selective activity against KSHV-associated primary effusion lymphoma and blocks vFLIP K13-induced NF-kappaB. Clin Cancer Res 19(18):5016\u20135026. https:\/\/doi.org\/10.1158\/1078-0432.CCR-12-3510","journal-title":"Clin Cancer Res"},{"issue":"10","key":"11_CR117","doi-asserted-by":"publisher","first-page":"5229","DOI":"10.1128\/JVI.00202-10","volume":"84","author":"E Gottwein","year":"2010","unstructured":"Gottwein E, Cullen BR (2010) A human herpesvirus microRNA inhibits p21 expression and attenuates p21-mediated cell cycle arrest. J Virol 84(10):5229\u20135237. https:\/\/doi.org\/10.1128\/JVI.00202-10","journal-title":"J Virol"},{"issue":"7172","key":"11_CR118","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.1038\/nature05992","volume":"450","author":"E Gottwein","year":"2007","unstructured":"Gottwein E, Mukherjee N, Sachse C, Frenzel C, Majoros WH, Chi JT et al (2007) A viral microRNA functions as an orthologue of cellular miR-155. Nature 450(7172):1096\u20131099. https:\/\/doi.org\/10.1038\/nature05992","journal-title":"Nature"},{"issue":"5","key":"11_CR119","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/j.chom.2011.09.012","volume":"10","author":"E Gottwein","year":"2011","unstructured":"Gottwein E, Corcoran DL, Mukherjee N, Skalsky RL, Hafner M, Nusbaum JD et al (2011) Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines. Cell Host Microbe 10(5):515\u2013526. https:\/\/doi.org\/10.1016\/j.chom.2011.09.012","journal-title":"Cell Host Microbe"},{"issue":"1","key":"11_CR120","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.virol.2007.12.044","volume":"375","author":"C Grossmann","year":"2008","unstructured":"Grossmann C, Ganem D (2008) Effects of NFkappaB activation on KSHV latency and lytic reactivation are complex and context-dependent. Virology 375(1):94\u2013102. https:\/\/doi.org\/10.1016\/j.virol.2007.12.044","journal-title":"Virology"},{"issue":"14","key":"11_CR121","doi-asserted-by":"publisher","first-page":"7179","DOI":"10.1128\/JVI.01603-05","volume":"80","author":"C Grossmann","year":"2006","unstructured":"Grossmann C, Podgrabinska S, Skobe M, Ganem D (2006) Activation of NF-kappaB by the latent vFLIP gene of Kaposi\u2019s sarcoma-associated herpesvirus is required for the spindle shape of virus-infected endothelial cells and contributes to their proinflammatory phenotype. J Virol 80(14):7179\u20137185. https:\/\/doi.org\/10.1128\/JVI.01603-05","journal-title":"J Virol"},{"issue":"7","key":"11_CR122","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1084\/jem.20031467","volume":"199","author":"I Guasparri","year":"2004","unstructured":"Guasparri I, Keller SA, Cesarman E (2004) KSHV vFLIP is essential for the survival of infected lymphoma cells. J Exp Med 199(7):993\u20131003. https:\/\/doi.org\/10.1084\/jem.20031467","journal-title":"J Exp Med"},{"issue":"1","key":"11_CR123","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1038\/sj.embor.7400580","volume":"7","author":"I Guasparri","year":"2006","unstructured":"Guasparri I, Wu H, Cesarman E (2006) The KSHV oncoprotein vFLIP contains a TRAF-interacting motif and requires TRAF2 and TRAF3 for signalling. EMBO Rep 7(1):114\u2013119. https:\/\/doi.org\/10.1038\/sj.embor.7400580","journal-title":"EMBO Rep"},{"issue":"4","key":"11_CR124","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1038\/sj.leu.2405081","volume":"22","author":"L Haddad","year":"2008","unstructured":"Haddad L, El Hajj H, Abou-Merhi R, Kfoury Y, Mahieux R, El-Sabban M et al (2008) KSHV-transformed primary effusion lymphoma cells induce a VEGF-dependent angiogenesis and establish functional gap junctions with endothelial cells. Leukemia 22(4):826\u2013834. https:\/\/doi.org\/10.1038\/sj.leu.2405081","journal-title":"Leukemia"},{"issue":"8","key":"11_CR125","doi-asserted-by":"publisher","first-page":"e1002884","DOI":"10.1371\/journal.ppat.1002884","volume":"8","author":"I Haecker","year":"2012","unstructured":"Haecker I, Gay LA, Yang Y, Hu J, Morse AM, McIntyre LM et al (2012) Ago HITS-CLIP expands understanding of Kaposi\u2019s sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas. PLoS Pathog 8(8):e1002884. https:\/\/doi.org\/10.1371\/journal.ppat.1002884","journal-title":"PLoS Pathog"},{"issue":"2","key":"11_CR126","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1101\/gad.553410","volume":"24","author":"A Hansen","year":"2010","unstructured":"Hansen A, Henderson S, Lagos D, Nikitenko L, Coulter E, Roberts S et al (2010) KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming. Genes Dev 24(2):195\u2013205. https:\/\/doi.org\/10.1101\/gad.553410","journal-title":"Genes Dev"},{"key":"11_CR127","first-page":"1","volume":"312","author":"GS Hayward","year":"2007","unstructured":"Hayward GS, Zong JC (2007) Modern evolutionary history of the human KSHV genome. Curr Top Microbiol Immunol 312:1\u201342","journal-title":"Curr Top Microbiol Immunol"},{"issue":"Pt 2","key":"11_CR128","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1042\/bj3340297","volume":"334","author":"PC Heinrich","year":"1998","unstructured":"Heinrich PC, Behrmann I, Muller-Newen G, Schaper F, Graeve L (1998) Interleukin-6-type cytokine signalling through the gp130\/Jak\/STAT pathway. Biochem J 334(Pt 2):297\u2013314","journal-title":"Biochem J"},{"issue":"Pt 1","key":"11_CR129","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1042\/BJ20030407","volume":"374","author":"PC Heinrich","year":"2003","unstructured":"Heinrich PC, Behrmann I, Haan S, Hermanns HM, Muller-Newen G, Schaper F (2003) Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem J 374(Pt 1):1\u201320. https:\/\/doi.org\/10.1042\/BJ20030407","journal-title":"Biochem J"},{"issue":"23","key":"11_CR130","doi-asserted-by":"publisher","first-page":"12255","DOI":"10.1128\/JVI.01484-10","volume":"84","author":"K Heinzelmann","year":"2010","unstructured":"Heinzelmann K, Scholz BA, Nowak A, Fossum E, Kremmer E, Haas J et al (2010) Kaposi\u2019s sarcoma-associated herpesvirus viral interferon regulatory factor 4 (vIRF4\/K10) is a novel interaction partner of CSL\/CBF1, the major downstream effector of Notch signaling. J Virol 84(23):12255\u201312264. https:\/\/doi.org\/10.1128\/JVI.01484-10","journal-title":"J Virol"},{"issue":"7","key":"11_CR131","doi-asserted-by":"publisher","first-page":"4295","DOI":"10.1093\/nar\/gkt082","volume":"41","author":"K Hew","year":"2013","unstructured":"Hew K, Dahlroth SL, Venkatachalam R, Nasertorabi F, Lim BT, Cornvik T et al (2013) The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor. Nucleic Acids Res 41(7):4295\u20134306. https:\/\/doi.org\/10.1093\/nar\/gkt082","journal-title":"Nucleic Acids Res"},{"issue":"15","key":"11_CR132","doi-asserted-by":"publisher","first-page":"9621","DOI":"10.1074\/jbc.272.15.9621","volume":"272","author":"S Hu","year":"1997","unstructured":"Hu S, Vincenz C, Buller M, Dixit VM (1997) A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis. J Biol Chem 272(15):9621\u20139624","journal-title":"J Biol Chem"},{"issue":"9","key":"11_CR133","doi-asserted-by":"publisher","first-page":"e1005171","DOI":"10.1371\/journal.ppat.1005171","volume":"11","author":"M Hu","year":"2015","unstructured":"Hu M, Wang C, Li W, Lu W, Bai Z, Qin D et al (2015) A KSHV microRNA directly targets G protein-coupled receptor kinase 2 to promote the migration and invasion of endothelial cells by inducing CXCR2 and activating AKT signaling. PLoS Pathog 11(9):e1005171. https:\/\/doi.org\/10.1371\/journal.ppat.1005171","journal-title":"PLoS Pathog"},{"issue":"3","key":"11_CR134","doi-asserted-by":"publisher","first-page":"1158","DOI":"10.1128\/JVI.01392-15","volume":"90","author":"H Hu","year":"2016","unstructured":"Hu H, Dong J, Liang D, Gao Z, Bai L, Sun R et al (2016) Genome-wide mapping of the binding sites and structural analysis of Kaposi\u2019s sarcoma-associated herpesvirus viral interferon regulatory factor 2 reveal that it is a DNA-binding transcription factor. J Virol 90(3):1158\u20131168. https:\/\/doi.org\/10.1128\/JVI.01392-15","journal-title":"J Virol"},{"issue":"6","key":"11_CR135","doi-asserted-by":"publisher","first-page":"3428","DOI":"10.1073\/pnas.062525799","volume":"99","author":"Q Huang","year":"2002","unstructured":"Huang Q, Petros AM, Virgin HW, Fesik SW, Olejniczak ET (2002) Solution structure of a Bcl-2 homolog from Kaposi sarcoma virus. Proc Natl Acad Sci U S A. 99(6):3428\u20133433. https:\/\/doi.org\/10.1073\/pnas.062525799","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"1","key":"11_CR136","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1128\/JVI.01903-15","volume":"90","author":"KY Hwang","year":"2016","unstructured":"Hwang KY, Choi YB (2016) Modulation of Mitochondrial Antiviral Signaling by Human Herpesvirus 8 Interferon Regulatory Factor 1. J Virol 90(1):506\u2013520. https:\/\/doi.org\/10.1128\/JVI.01903-15","journal-title":"J Virol"},{"issue":"3","key":"11_CR137","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1111\/j.1365-2141.1994.tb04777.x","volume":"86","author":"T Ishiyama","year":"1994","unstructured":"Ishiyama T, Nakamura S, Akimoto Y, Koike M, Tomoyasu S, Tsuruoka N et al (1994) Immunodeficiency and IL-6 production by peripheral blood monocytes in multicentric Castleman\u2019s disease. Br J Haematol 86(3):483\u2013489","journal-title":"Br J Haematol"},{"key":"11_CR138","doi-asserted-by":"publisher","first-page":"19","DOI":"10.3389\/fimmu.2011.00019","volume":"2","author":"SR Jacobs","year":"2011","unstructured":"Jacobs SR, Damania B (2011) The viral interferon regulatory factors of KSHV: immunosuppressors or oncogenes? Front Immunol 2:19. https:\/\/doi.org\/10.3389\/fimmu.2011.00019","journal-title":"Front Immunol"},{"issue":"6","key":"11_CR139","doi-asserted-by":"publisher","first-page":"2430","DOI":"10.1128\/MCB.26.6.2430-2440.2006","volume":"26","author":"A Jarviluoma","year":"2006","unstructured":"Jarviluoma A, Child ES, Sarek G, Sirimongkolkasem P, Peters G, Ojala PM et al (2006) Phosphorylation of the cyclin-dependent kinase inhibitor p21Cip1 on serine 130 is essential for viral cyclin-mediated bypass of a p21Cip1-imposed G1 arrest. Mol Cell Biol 26(6):2430\u20132440. https:\/\/doi.org\/10.1128\/MCB.26.6.2430-2440.2006","journal-title":"Mol Cell Biol"},{"issue":"2","key":"11_CR140","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1128\/JVI.75.2.891-902.2001","volume":"75","author":"RG Jenner","year":"2001","unstructured":"Jenner RG, Alba MM, Boshoff C, Kellam P (2001) Kaposi\u2019s sarcoma-associated herpesvirus latent and lytic gene expression as revealed by DNA arrays. J Virol 75(2):891\u2013902. https:\/\/doi.org\/10.1128\/JVI.75.2.891-902.2001","journal-title":"J Virol"},{"issue":"8","key":"11_CR141","doi-asserted-by":"publisher","first-page":"2871","DOI":"10.1182\/blood.V94.8.2871.420k25_2871_2879","volume":"94","author":"KD Jones","year":"1999","unstructured":"Jones KD, Aoki Y, Chang Y, Moore PS, Yarchoan R, Tosato G (1999) Involvement of interleukin-10 (IL-10) and viral IL-6 in the spontaneous growth of Kaposi\u2019s sarcoma herpesvirus-associated infected primary effusion lymphoma cells. Blood 94(8):2871\u20132879","journal-title":"Blood"},{"key":"11_CR142","doi-asserted-by":"publisher","unstructured":"Jones T, Ramos da Silva S, Bedolla R, Ye F, Zhou F, Gao SJ (2014) Viral cyclin promotes KSHV-induced cellular transformation and tumorigenesis by overriding contact inhibition. Cell Cycle 13(5):845\u201358. https:\/\/doi.org\/10.4161\/cc.27758","DOI":"10.4161\/cc.27758"},{"issue":"15","key":"11_CR143","doi-asserted-by":"publisher","first-page":"8282","DOI":"10.1128\/JVI.00235-07","volume":"81","author":"CH Joo","year":"2007","unstructured":"Joo CH, Shin YC, Gack M, Wu L, Levy D, Jung JU (2007) Inhibition of interferon regulatory factor 7 (IRF7)-mediated interferon signal transduction by the Kaposi\u2019s sarcoma-associated herpesvirus viral IRF homolog vIRF3. J Virol 81(15):8282\u20138292. https:\/\/doi.org\/10.1128\/JVI.00235-07","journal-title":"J Virol"},{"key":"11_CR144","doi-asserted-by":"publisher","unstructured":"Journo G, Tushinsky C, Shterngas A, Avital N, Eran Y, Karpuj MV et al (2018) Modulation of cellular CpG DNA methylation by Kaposi\u2019s sarcoma-associated herpesvirus. J Virol 92(16). https:\/\/doi.org\/10.1128\/jvi.00008-18","DOI":"10.1128\/jvi.00008-18"},{"issue":"2","key":"11_CR145","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1080\/00313020410001671957","volume":"36","author":"R Karim","year":"2004","unstructured":"Karim R, Tse G, Putti T, Scolyer R, Lee S (2004) The significance of the Wnt pathway in the pathology of human cancers. Pathology. 36(2):120\u2013128. https:\/\/doi.org\/10.1080\/00313020410001671957","journal-title":"Pathology."},{"issue":"2","key":"11_CR146","first-page":"108","volume":"71","author":"K Kawa","year":"2000","unstructured":"Kawa K (2000) Epstein-Barr virus\u2013associated diseases in humans. Int J Hematol 71(2):108\u2013117","journal-title":"Int J Hematol"},{"issue":"19","key":"11_CR147","doi-asserted-by":"publisher","first-page":"9150","DOI":"10.1073\/pnas.90.19.9150","volume":"90","author":"KM Kaye","year":"1993","unstructured":"Kaye KM, Izumi KM, Kieff E (1993) Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformation. Proc Natl Acad Sci U S A. 90(19):9150\u20139154","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"7","key":"11_CR148","doi-asserted-by":"publisher","first-page":"2537","DOI":"10.1182\/blood.V96.7.2537.h8002537_2537_2542","volume":"96","author":"SA Keller","year":"2000","unstructured":"Keller SA, Schattner EJ, Cesarman E (2000) Inhibition of NF-kappaB induces apoptosis of KSHV-infected primary effusion lymphoma cells. Blood 96(7):2537\u20132542","journal-title":"Blood"},{"issue":"8","key":"11_CR149","doi-asserted-by":"publisher","first-page":"e0135560","DOI":"10.1371\/journal.pone.0135560","volume":"10","author":"P Kieffer-Kwon","year":"2015","unstructured":"Kieffer-Kwon P, Happel C, Uldrick TS, Ramalingam D, Ziegelbauer JM (2015) KSHV MicroRNAs repress tropomyosin 1 and increase anchorage-independent growth and endothelial tube formation. PLoS ONE 10(8):e0135560. https:\/\/doi.org\/10.1371\/journal.pone.0135560","journal-title":"PLoS ONE"},{"issue":"3","key":"11_CR150","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1016\/j.bbrc.2016.01.087","volume":"470","author":"Y Kim","year":"2016","unstructured":"Kim Y, Cha S, Seo T (2016) Activation of the phosphatidylinositol 3-kinase\/Akt pathway by viral interferon regulatory factor 2 of Kaposi\u2019s sarcoma-associated herpesvirus. Biochem Biophys Res Commun 470(3):650\u2013656. https:\/\/doi.org\/10.1016\/j.bbrc.2016.01.087","journal-title":"Biochem Biophys Res Commun"},{"issue":"4","key":"11_CR151","doi-asserted-by":"publisher","first-page":"1243","DOI":"10.1182\/blood.V86.4.1243.bloodjournal8641243","volume":"86","author":"T Kishimoto","year":"1995","unstructured":"Kishimoto T, Akira S, Narazaki M, Taga T (1995) Interleukin-6 family of cytokines and gp130. Blood 86(4):1243\u20131254","journal-title":"Blood"},{"issue":"5332","key":"11_CR152","doi-asserted-by":"publisher","first-page":"1656","DOI":"10.1126\/science.277.5332.1656","volume":"277","author":"TN Kledal","year":"1997","unstructured":"Kledal TN, Rosenkilde MM, Coulin F, Simmons G, Johnsen AH, Alouani S et al (1997) A broad-spectrum chemokine antagonist encoded by Kaposi\u2019s sarcoma-associated herpesvirus. Science 277(5332):1656\u20131659","journal-title":"Science"},{"issue":"2","key":"11_CR153","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/S1097-2765(00)00040-X","volume":"6","author":"MF Kleijnen","year":"2000","unstructured":"Kleijnen MF, Shih AH, Zhou P, Kumar S, Soccio RE, Kedersha NL et al (2000) The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome. Mol Cell 6(2):409\u2013419","journal-title":"Mol Cell"},{"issue":"4","key":"11_CR154","doi-asserted-by":"publisher","first-page":"833","DOI":"10.1016\/S1097-2765(01)00227-1","volume":"7","author":"S Kliche","year":"2001","unstructured":"Kliche S, Nagel W, Kremmer E, Atzler C, Ege A, Knorr T et al (2001) Signaling by human herpesvirus 8 kaposin A through direct membrane recruitment of cytohesin-1. Mol Cell 7(4):833\u2013843","journal-title":"Mol Cell"},{"issue":"17","key":"11_CR155","doi-asserted-by":"publisher","first-page":"8510","DOI":"10.1128\/JVI.00420-06","volume":"80","author":"M Kovaleva","year":"2006","unstructured":"Kovaleva M, Bussmeyer I, Rabe B, Grotzinger J, Sudarman E, Eichler J et al (2006) Abrogation of viral interleukin-6 (vIL-6)-induced signaling by intracellular retention and neutralization of vIL-6 with an anti-vIL-6 single-chain antibody selected by phage display. J Virol 80(17):8510\u20138520. https:\/\/doi.org\/10.1128\/JVI.00420-06","journal-title":"J Virol"},{"issue":"20","key":"11_CR156","doi-asserted-by":"publisher","first-page":"9637","DOI":"10.1128\/JVI.74.20.9637-9645.2000","volume":"74","author":"A Krithivas","year":"2000","unstructured":"Krithivas A, Young DB, Liao G, Greene D, Hayward SD (2000) Human herpesvirus 8 LANA interacts with proteins of the mSin3 corepressor complex and negatively regulates Epstein-Barr virus gene expression in dually infected PEL cells. J Virol 74(20):9637\u20139645","journal-title":"J Virol"},{"issue":"4","key":"11_CR157","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/j.molcel.2005.02.003","volume":"17","author":"T Kuwana","year":"2005","unstructured":"Kuwana T, Bouchier-Hayes L, Chipuk JE, Bonzon C, Sullivan BA, Green DR et al (2005) BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Mol Cell 17(4):525\u2013535. https:\/\/doi.org\/10.1016\/j.molcel.2005.02.003","journal-title":"Mol Cell"},{"issue":"1","key":"11_CR158","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1006\/viro.1997.8713","volume":"236","author":"M Lagunoff","year":"1997","unstructured":"Lagunoff M, Ganem D (1997) The structure and coding organization of the genomic termini of Kaposi\u2019s sarcoma-associated herpesvirus. Virology 236(1):147\u2013154","journal-title":"Virology"},{"issue":"13","key":"11_CR159","doi-asserted-by":"publisher","first-page":"5891","DOI":"10.1128\/JVI.75.13.5891-5898.2001","volume":"75","author":"M Lagunoff","year":"2001","unstructured":"Lagunoff M, Lukac DM, Ganem D (2001) Immunoreceptor tyrosine-based activation motif-dependent signaling by Kaposi\u2019s sarcoma-associated herpesvirus K1 protein: effects on lytic viral replication. J Virol 75(13):5891\u20135898. https:\/\/doi.org\/10.1128\/JVI.75.13.5891-5898.2001","journal-title":"J Virol"},{"issue":"9","key":"11_CR160","doi-asserted-by":"publisher","first-page":"e1007253","DOI":"10.1371\/journal.ppat.1007253","volume":"14","author":"F Lang","year":"2018","unstructured":"Lang F, Sun Z, Pei Y, Singh RK, Jha HC, Robertson ES (2018) Shugoshin 1 is dislocated by KSHV-encoded LANA inducing aneuploidy. PLoS Pathog 14(9):e1007253. https:\/\/doi.org\/10.1371\/journal.ppat.1007253","journal-title":"PLoS Pathog"},{"issue":"2","key":"11_CR161","doi-asserted-by":"publisher","first-page":"277","DOI":"10.4161\/15384101.2014.980657","volume":"14","author":"MV Laura","year":"2015","unstructured":"Laura MV, de la Cruz-Herrera CF, Ferreiros A, Baz-Martinez M, Lang V, Vidal A et al (2015) KSHV latent protein LANA2 inhibits sumo2 modification of p53. Cell Cycle 14(2):277\u2013282. https:\/\/doi.org\/10.4161\/15384101.2014.980657","journal-title":"Cell Cycle"},{"issue":"4","key":"11_CR162","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1038\/nm0498-435","volume":"4","author":"H Lee","year":"1998","unstructured":"Lee H, Veazey R, Williams K, Li M, Guo J, Neipel F et al (1998a) Deregulation of cell growth by the K1 gene of Kaposi\u2019s sarcoma-associated herpesvirus. Nat Med 4(4):435\u2013440","journal-title":"Nat Med"},{"issue":"9","key":"11_CR163","doi-asserted-by":"publisher","first-page":"5219","DOI":"10.1128\/MCB.18.9.5219","volume":"18","author":"H Lee","year":"1998","unstructured":"Lee H, Guo J, Li M, Choi JK, DeMaria M, Rosenzweig M et al (1998b) Identification of an immunoreceptor tyrosine-based activation motif of K1 transforming protein of Kaposi\u2019s sarcoma-associated herpesvirus. Mol Cell Biol 18(9):5219\u20135228","journal-title":"Mol Cell Biol"},{"issue":"6956","key":"11_CR164","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1038\/nature01957","volume":"425","author":"Y Lee","year":"2003","unstructured":"Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J et al (2003a) The nuclear RNase III Drosha initiates microRNA processing. Nature 425(6956):415\u2013419. https:\/\/doi.org\/10.1038\/nature01957","journal-title":"Nature"},{"issue":"1","key":"11_CR165","doi-asserted-by":"publisher","first-page":"243","DOI":"10.4049\/jimmunol.170.1.243","volume":"170","author":"BJ Lee","year":"2003","unstructured":"Lee BJ, Koszinowski UH, Sarawar SR, Adler H (2003b) A gammaherpesvirus G protein-coupled receptor homologue is required for increased viral replication in response to chemokines and efficient reactivation from latency. J Immunol. 170(1):243\u2013251","journal-title":"J Immunol."},{"issue":"14","key":"11_CR166","doi-asserted-by":"publisher","first-page":"8072","DOI":"10.1128\/JVI.77.14.8072-8086.2003","volume":"77","author":"BS Lee","year":"2003","unstructured":"Lee BS, Connole M, Tang Z, Harris NL, Jung JU (2003c) Structural analysis of the Kaposi\u2019s sarcoma-associated herpesvirus K1 protein. J Virol 77(14):8072\u20138086","journal-title":"J Virol"},{"issue":"19","key":"11_CR167","doi-asserted-by":"publisher","first-page":"12173","DOI":"10.1128\/JVI.79.19.12173-12184.2005","volume":"79","author":"BS Lee","year":"2005","unstructured":"Lee BS, Lee SH, Feng P, Chang H, Cho NH, Jung JU (2005) Characterization of the Kaposi\u2019s sarcoma-associated herpesvirus K1 signalosome. J Virol 79(19):12173\u201312184. https:\/\/doi.org\/10.1128\/JVI.79.19.12173-12184.2005","journal-title":"J Virol"},{"issue":"11","key":"11_CR168","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.1038\/ncb1980","volume":"11","author":"JS Lee","year":"2009","unstructured":"Lee JS, Li Q, Lee JY, Lee SH, Jeong JH, Lee HR et al (2009a) FLIP-mediated autophagy regulation in cell death control. Nat Cell Biol 11(11):1355\u20131362. https:\/\/doi.org\/10.1038\/ncb1980","journal-title":"Nat Cell Biol"},{"issue":"9","key":"11_CR169","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1089\/jir.2009.0067","volume":"29","author":"HR Lee","year":"2009","unstructured":"Lee HR, Kim MH, Lee JS, Liang C, Jung JU (2009b) Viral interferon regulatory factors. J Interferon Cytokine Res 29(9):621\u2013627. https:\/\/doi.org\/10.1089\/jir.2009.0067","journal-title":"J Interferon Cytokine Res"},{"issue":"13","key":"11_CR170","doi-asserted-by":"publisher","first-page":"6739","DOI":"10.1128\/JVI.02353-08","volume":"83","author":"HR Lee","year":"2009","unstructured":"Lee HR, Toth Z, Shin YC, Lee JS, Chang H, Gu W et al (2009c) Kaposi\u2019s sarcoma-associated herpesvirus viral interferon regulatory factor 4 targets MDM2 to deregulate the p53 tumor suppressor pathway. J Virol 83(13):6739\u20136747. https:\/\/doi.org\/10.1128\/JVI.02353-08","journal-title":"J Virol"},{"issue":"12","key":"11_CR171","doi-asserted-by":"publisher","first-page":"1336","DOI":"10.1038\/nsmb.2142","volume":"18","author":"HR Lee","year":"2011","unstructured":"Lee HR, Choi WC, Lee S, Hwang J, Hwang E, Guchhait K et al (2011) Bilateral inhibition of HAUSP deubiquitinase by a viral interferon regulatory factor protein. Nat Struct Mol Biol 18(12):1336\u20131344. https:\/\/doi.org\/10.1038\/nsmb.2142","journal-title":"Nat Struct Mol Biol"},{"key":"11_CR172","doi-asserted-by":"publisher","unstructured":"Lee HR, Li F, Choi UY, Yu HR, Aldrovandi GM, Feng P et al (2018) Deregulation of HDAC5 by viral interferon regulatory factor 3 plays an essential role in Kaposi\u2019s sarcoma-associated herpesvirus-induced lymphangiogenesis. MBio 9(1). https:\/\/doi.org\/10.1128\/mbio.02217-17","DOI":"10.1128\/mbio.02217-17"},{"issue":"2","key":"11_CR173","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1038\/ncb2019","volume":"12","author":"X Lei","year":"2010","unstructured":"Lei X, Bai Z, Ye F, Xie J, Kim CG, Huang Y et al (2010) Regulation of NF-kappaB inhibitor IkappaBalpha and viral replication by a KSHV microRNA. Nat Cell Biol 12(2):193\u2013199. https:\/\/doi.org\/10.1038\/ncb2019","journal-title":"Nat Cell Biol"},{"issue":"21","key":"11_CR174","doi-asserted-by":"publisher","first-page":"11698","DOI":"10.1128\/JVI.06855-11","volume":"86","author":"X Lei","year":"2012","unstructured":"Lei X, Zhu Y, Jones T, Bai Z, Huang Y, Gao SJ (2012) A Kaposi\u2019s sarcoma-associated herpesvirus microRNA and its variants target the transforming growth factor beta pathway to promote cell survival. J Virol 86(21):11698\u201311711. https:\/\/doi.org\/10.1128\/JVI.06855-11","journal-title":"J Virol"},{"issue":"3","key":"11_CR175","doi-asserted-by":"publisher","first-page":"1984","DOI":"10.1128\/jvi.71.3.1984-1991.1997","volume":"71","author":"M Li","year":"1997","unstructured":"Li M, Lee H, Yoon DW, Albrecht JC, Fleckenstein B, Neipel F et al (1997) Kaposi\u2019s sarcoma-associated herpesvirus encodes a functional cyclin. J Virol 71(3):1984\u20131991","journal-title":"J Virol"},{"issue":"21","key":"11_CR176","doi-asserted-by":"publisher","first-page":"8254","DOI":"10.1128\/MCB.20.21.8254-8263.2000","volume":"20","author":"M Li","year":"2000","unstructured":"Li M, Damania B, Alvarez X, Ogryzko V, Ozato K, Jung JU (2000) Inhibition of p300 histone acetyltransferase by viral interferon regulatory factor. Mol Cell Biol 20(21):8254\u20138263","journal-title":"Mol Cell Biol"},{"issue":"23","key":"11_CR177","doi-asserted-by":"publisher","first-page":"11880","DOI":"10.1128\/JVI.76.23.11880-11888.2002","volume":"76","author":"H Li","year":"2002","unstructured":"Li H, Komatsu T, Dezube BJ, Kaye KM (2002a) The Kaposi\u2019s sarcoma-associated herpesvirus K12 transcript from a primary effusion lymphoma contains complex repeat elements, is spliced, and initiates from a novel promoter. J Virol 76(23):11880\u201311888","journal-title":"J Virol"},{"issue":"6881","key":"11_CR178","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1038\/nature737","volume":"416","author":"M Li","year":"2002","unstructured":"Li M, Chen D, Shiloh A, Luo J, Nikolaev AY, Qin J et al (2002b) Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. Nature 416(6881):648\u2013653. https:\/\/doi.org\/10.1038\/nature737","journal-title":"Nature"},{"issue":"6","key":"11_CR179","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1016\/S1097-2765(04)00157-1","volume":"13","author":"M Li","year":"2004","unstructured":"Li M, Brooks CL, Kon N, Gu W (2004) A dynamic role of HAUSP in the p53-Mdm2 pathway. Mol Cell 13(6):879\u2013886","journal-title":"Mol Cell"},{"issue":"2","key":"11_CR180","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1038\/cmi.2012.62","volume":"10","author":"J Li","year":"2013","unstructured":"Li J, Wan Y, Ji Q, Fang Y, Wu Y (2013) The role of microRNAs in B-cell development and function. Cell Mol Immunol 10(2):107\u2013112. https:\/\/doi.org\/10.1038\/cmi.2012.62","journal-title":"Cell Mol Immunol"},{"issue":"22","key":"11_CR181","doi-asserted-by":"publisher","first-page":"32286","DOI":"10.18632\/oncotarget.8591","volume":"7","author":"W Li","year":"2016","unstructured":"Li W, Jia X, Shen C, Zhang M, Xu J, Shang Y et al (2016a) A KSHV microRNA enhances viral latency and induces angiogenesis by targeting GRK2 to activate the CXCR2\/AKT pathway. Oncotarget 7(22):32286\u201332305. https:\/\/doi.org\/10.18632\/oncotarget.8591","journal-title":"Oncotarget"},{"issue":"4","key":"11_CR182","doi-asserted-by":"publisher","first-page":"e1005605","DOI":"10.1371\/journal.ppat.1005605","volume":"12","author":"W Li","year":"2016","unstructured":"Li W, Yan Q, Ding X, Shen C, Hu M, Zhu Y et al (2016b) The SH3BGR\/STAT3 Pathway Regulates Cell Migration and Angiogenesis Induced by a Gammaherpesvirus MicroRNA. PLoS Pathog 12(4):e1005605. https:\/\/doi.org\/10.1371\/journal.ppat.1005605","journal-title":"PLoS Pathog"},{"issue":"38","key":"11_CR183","doi-asserted-by":"publisher","first-page":"5407","DOI":"10.1038\/onc.2017.139","volume":"36","author":"W Li","year":"2017","unstructured":"Li W, Hu M, Wang C, Lu H, Chen F, Xu J et al (2017) A viral microRNA downregulates metastasis suppressor CD82 and induces cell invasion and angiogenesis by activating the c-Met signaling. Oncogene 36(38):5407\u20135420. https:\/\/doi.org\/10.1038\/onc.2017.139","journal-title":"Oncogene"},{"key":"11_CR184","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02026-18","author":"Q Li","year":"2018","unstructured":"Li Q, Chen D, Xiang Q, Nicholas J (2018) Insulin-like growth factor 2 receptor expression is promoted by human herpesvirus 8-encoded interleukin-6 and contributes to viral latency and productive replication. J Virol. https:\/\/doi.org\/10.1128\/JVI.02026-18","journal-title":"J Virol"},{"key":"11_CR185","doi-asserted-by":"publisher","unstructured":"Li T, Zhu Y, Cheng F, Lu C, Jung JU, Gao SJ (2019) Oncogenic Kaposi\u2019s sarcoma-associated herpesvirus upregulates argininosuccinate synthase 1, a rate-limiting enzyme of the citrulline-nitric oxide cycle, to activate the STAT3 pathway and promote growth transformation. J Virol 93(4). https:\/\/doi.org\/10.1128\/jvi.01599-18","DOI":"10.1128\/jvi.01599-18"},{"issue":"7","key":"11_CR186","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1038\/ncb1426","volume":"8","author":"C Liang","year":"2006","unstructured":"Liang C, Feng P, Ku B, Dotan I, Canaani D, Oh BH et al (2006) Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol 8(7):688\u2013699. https:\/\/doi.org\/10.1038\/ncb1426","journal-title":"Nat Cell Biol"},{"key":"11_CR187","doi-asserted-by":"publisher","first-page":"271","DOI":"10.3389\/fmicb.2011.00271","volume":"2","author":"D Liang","year":"2011","unstructured":"Liang D, Lin X, Lan K (2011a) Looking at Kaposi\u2019s Sarcoma-Associated Herpesvirus-Host Interactions from a microRNA Viewpoint. Front Microbiol. 2:271. https:\/\/doi.org\/10.3389\/fmicb.2011.00271","journal-title":"Front Microbiol."},{"issue":"5","key":"11_CR188","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1038\/cr.2011.5","volume":"21","author":"D Liang","year":"2011","unstructured":"Liang D, Gao Y, Lin X, He Z, Zhao Q, Deng Q et al (2011b) A human herpesvirus miRNA attenuates interferon signaling and contributes to maintenance of viral latency by targeting IKKepsilon. Cell Res 21(5):793\u2013806. https:\/\/doi.org\/10.1038\/cr.2011.5","journal-title":"Cell Res"},{"issue":"22","key":"11_CR189","doi-asserted-by":"publisher","first-page":"12499","DOI":"10.1128\/JVI.01898-13","volume":"87","author":"Q Liang","year":"2013","unstructured":"Liang Q, Chang B, Brulois KF, Castro K, Min CK, Rodgers MA et al (2013) Kaposi\u2019s sarcoma-associated herpesvirus K7 modulates Rubicon-mediated inhibition of autophagosome maturation. J Virol 87(22):12499\u201312503. https:\/\/doi.org\/10.1128\/JVI.01898-13","journal-title":"J Virol"},{"issue":"10","key":"11_CR190","doi-asserted-by":"publisher","first-page":"5308","DOI":"10.1128\/JVI.00102-15","volume":"89","author":"Q Liang","year":"2015","unstructured":"Liang Q, Chang B, Lee P, Brulois KF, Ge J, Shi M et al (2015) Identification of the essential role of viral Bcl-2 for Kaposi\u2019s sarcoma-associated herpesvirus lytic replication. J Virol 89(10):5308\u20135317. https:\/\/doi.org\/10.1128\/JVI.00102-15","journal-title":"J Virol"},{"key":"11_CR191","doi-asserted-by":"publisher","unstructured":"Liang Q, Wei D, Chung B, Brulois KF, Guo C, Dong S et al (2018) Novel role of vBcl2 in the virion assembly of Kaposi\u2019s sarcoma-associated herpesvirus. J Virol 92(4). https:\/\/doi.org\/10.1128\/jvi.00914-17","DOI":"10.1128\/jvi.00914-17"},{"issue":"35","key":"11_CR192","doi-asserted-by":"publisher","first-page":"9874","DOI":"10.1021\/bi700357s","volume":"46","author":"CS Lim","year":"2007","unstructured":"Lim CS, Seet BT, Ingham RJ, Gish G, Matskova L, Winberg G et al (2007) The K15 protein of Kaposi\u2019s sarcoma-associated herpesvirus recruits the endocytic regulator intersectin 2 through a selective SH3 domain interaction. Biochemistry 46(35):9874\u20139885. https:\/\/doi.org\/10.1021\/bi700357s","journal-title":"Biochemistry"},{"issue":"7","key":"11_CR193","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1038\/sj.onc.1204163","volume":"20","author":"R Lin","year":"2001","unstructured":"Lin R, Genin P, Mamane Y, Sgarbanti M, Battistini A, Harrington WJ Jr et al (2001) HHV-8 encoded vIRF-1 represses the interferon antiviral response by blocking IRF-3 recruitment of the CBP\/p300 coactivators. Oncogene 20(7):800\u2013811. https:\/\/doi.org\/10.1038\/sj.onc.1204163","journal-title":"Oncogene"},{"issue":"1","key":"11_CR194","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.jviromet.2007.02.010","volume":"143","author":"CW Lin","year":"2007","unstructured":"Lin CW, Tu PF, Hsiao NW, Chang CY, Wan L, Lin YT et al (2007) Identification of a novel septin 4 protein binding to human herpesvirus 8 kaposin A protein using a phage display cDNA library. J Virol Methods 143(1):65\u201372. https:\/\/doi.org\/10.1016\/j.jviromet.2007.02.010","journal-title":"J Virol Methods"},{"issue":"1","key":"11_CR195","doi-asserted-by":"publisher","first-page":"e16224","DOI":"10.1371\/journal.pone.0016224","volume":"6","author":"X Lin","year":"2011","unstructured":"Lin X, Liang D, He Z, Deng Q, Robertson ES, Lan K (2011) miR-K12-7-5p encoded by Kaposi\u2019s sarcoma-associated herpesvirus stabilizes the latent state by targeting viral ORF50\/RTA. PLoS ONE 6(1):e16224. https:\/\/doi.org\/10.1371\/journal.pone.0016224","journal-title":"PLoS ONE"},{"issue":"1","key":"11_CR196","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.plasmid.2007.01.003","volume":"58","author":"SE Lindner","year":"2007","unstructured":"Lindner SE, Sugden B (2007) The plasmid replicon of Epstein-Barr virus: mechanistic insights into efficient, licensed, extrachromosomal replication in human cells. Plasmid 58(1):1\u201312. https:\/\/doi.org\/10.1016\/j.plasmid.2007.01.003","journal-title":"Plasmid"},{"issue":"22","key":"11_CR197","doi-asserted-by":"publisher","first-page":"10933","DOI":"10.1128\/JVI.75.22.10933-10940.2001","volume":"75","author":"C Liu","year":"2001","unstructured":"Liu C, Okruzhnov Y, Li H, Nicholas J (2001) Human herpesvirus 8 (HHV-8)-encoded cytokines induce expression of and autocrine signaling by vascular endothelial growth factor (VEGF) in HHV-8-infected primary-effusion lymphoma cell lines and mediate VEGF-independent antiapoptotic effects. J Virol 75(22):10933\u201310940. https:\/\/doi.org\/10.1128\/JVI.75.22.10933-10940.2001","journal-title":"J Virol"},{"issue":"16","key":"11_CR198","doi-asserted-by":"publisher","first-page":"13745","DOI":"10.1074\/jbc.M110480200","volume":"277","author":"L Liu","year":"2002","unstructured":"Liu L, Eby MT, Rathore N, Sinha SK, Kumar A, Chaudhary PM (2002) The human herpes virus 8-encoded viral FLICE inhibitory protein physically associates with and persistently activates the Ikappa B kinase complex. J Biol Chem 277(16):13745\u201313751. https:\/\/doi.org\/10.1074\/jbc.M110480200","journal-title":"J Biol Chem"},{"issue":"5","key":"11_CR199","doi-asserted-by":"publisher","first-page":"2460","DOI":"10.1128\/JVI.78.5.2460-2471.2004","volume":"78","author":"C Liu","year":"2004","unstructured":"Liu C, Sandford G, Fei G, Nicholas J (2004) Galpha protein selectivity determinant specified by a viral chemokine receptor-conserved region in the C tail of the human herpesvirus 8\u00a0g protein-coupled receptor. J Virol 78(5):2460\u20132471","journal-title":"J Virol"},{"issue":"9","key":"11_CR200","doi-asserted-by":"publisher","first-page":"4722","DOI":"10.1128\/JVI.02548-06","volume":"81","author":"J Liu","year":"2007","unstructured":"Liu J, Martin H, Shamay M, Woodard C, Tang QQ, Hayward SD (2007a) Kaposi\u2019s sarcoma-associated herpesvirus LANA protein downregulates nuclear glycogen synthase kinase 3 activity and consequently blocks differentiation. J Virol 81(9):4722\u20134731. https:\/\/doi.org\/10.1128\/JVI.02548-06","journal-title":"J Virol"},{"issue":"19","key":"11_CR201","doi-asserted-by":"publisher","first-page":"10451","DOI":"10.1128\/JVI.00804-07","volume":"81","author":"J Liu","year":"2007","unstructured":"Liu J, Martin HJ, Liao G, Hayward SD (2007b) The Kaposi\u2019s sarcoma-associated herpesvirus LANA protein stabilizes and activates c-Myc. J Virol 81(19):10451\u201310459. https:\/\/doi.org\/10.1128\/JVI.00804-07","journal-title":"J Virol"},{"issue":"3","key":"11_CR202","doi-asserted-by":"publisher","first-page":"1372","DOI":"10.1128\/JVI.06245-11","volume":"86","author":"Y Liu","year":"2012","unstructured":"Liu Y, Sun R, Lin X, Liang D, Deng Q, Lan K (2012) Kaposi\u2019s sarcoma-associated herpesvirus-encoded microRNA miR-K12-11 attenuates transforming growth factor beta signaling through suppression of SMAD5. J Virol 86(3):1372\u20131381. https:\/\/doi.org\/10.1128\/JVI.06245-11","journal-title":"J Virol"},{"key":"11_CR203","doi-asserted-by":"publisher","unstructured":"Liu X, Happel C, Ziegelbauer JM (2017) Kaposi\u2019s sarcoma-associated herpesvirus MicroRNAs target GADD45B to protect infected cells from cell cycle arrest and apoptosis. J Virol 91(3). https:\/\/doi.org\/10.1128\/jvi.02045-16","DOI":"10.1128\/jvi.02045-16"},{"issue":"53","key":"11_CR204","doi-asserted-by":"publisher","first-page":"41328","DOI":"10.1074\/jbc.M110.146852","volume":"285","author":"F Louafi","year":"2010","unstructured":"Louafi F, Martinez-Nunez RT, Sanchez-Elsner T (2010) MicroRNA-155 targets SMAD2 and modulates the response of macrophages to transforming growth factor-\u03b2. J Biol Chem 285(53):41328\u201341336. https:\/\/doi.org\/10.1074\/jbc.M110.146852","journal-title":"J Biol Chem"},{"issue":"2","key":"11_CR205","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1002\/immu.200310025","volume":"33","author":"J Louahed","year":"2003","unstructured":"Louahed J, Struyf S, Demoulin JB, Parmentier M, Van Snick J, Van Damme J et al (2003) CCR8-dependent activation of the RAS\/MAPK pathway mediates anti-apoptotic activity of I-309\/ CCL1 and vMIP-I. Eur J Immunol 33(2):494\u2013501. https:\/\/doi.org\/10.1002\/immu.200310025","journal-title":"Eur J Immunol"},{"issue":"6","key":"11_CR206","doi-asserted-by":"publisher","first-page":"2697","DOI":"10.1128\/JVI.01997-09","volume":"84","author":"F Lu","year":"2010","unstructured":"Lu F, Stedman W, Yousef M, Renne R, Lieberman PM (2010a) Epigenetic regulation of Kaposi\u2019s sarcoma-associated herpesvirus latency by virus-encoded microRNAs that target Rta and the cellular Rbl2-DNMT pathway. J Virol 84(6):2697\u20132706. https:\/\/doi.org\/10.1128\/JVI.01997-09","journal-title":"J Virol"},{"issue":"10","key":"11_CR207","doi-asserted-by":"publisher","first-page":"784","DOI":"10.1038\/embor.2010.132","volume":"11","author":"CC Lu","year":"2010","unstructured":"Lu CC, Li Z, Chu CY, Feng J, Feng J, Sun R et al (2010b) MicroRNAs encoded by Kaposi\u2019s sarcoma-associated herpesvirus regulate viral life cycle. EMBO Rep 11(10):784\u2013790. https:\/\/doi.org\/10.1038\/embor.2010.132","journal-title":"EMBO Rep"},{"issue":"17","key":"11_CR208","doi-asserted-by":"publisher","first-page":"8194","DOI":"10.1128\/JVI.74.17.8194-8201.2000","volume":"74","author":"B Lubyova","year":"2000","unstructured":"Lubyova B, Pitha PM (2000) Characterization of a novel human herpesvirus 8-encoded protein, vIRF-3, that shows homology to viral and cellular interferon regulatory factors. J Virol 74(17):8194\u20138201","journal-title":"J Virol"},{"issue":"44","key":"11_CR209","doi-asserted-by":"publisher","first-page":"31944","DOI":"10.1074\/jbc.M706430200","volume":"282","author":"B Lubyova","year":"2007","unstructured":"Lubyova B, Kellum MJ, Frisancho JA, Pitha PM (2007) Stimulation of c-Myc transcriptional activity by vIRF-3 of Kaposi sarcoma-associated herpesvirus. J Biol Chem 282(44):31944\u201331953. https:\/\/doi.org\/10.1074\/jbc.M706430200","journal-title":"J Biol Chem"},{"issue":"5654","key":"11_CR210","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1126\/science.1090599","volume":"303","author":"E Lund","year":"2004","unstructured":"Lund E, Guttinger S, Calado A, Dahlberg JE, Kutay U (2004) Nuclear export of microRNA precursors. Science 303(5654):95\u201398. https:\/\/doi.org\/10.1126\/science.1090599","journal-title":"Science"},{"key":"11_CR211","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1186\/1743-422X-5-50","volume":"5","author":"HR Luttichau","year":"2008","unstructured":"Luttichau HR (2008) The herpesvirus 8 encoded chemokines vCCL2 (vMIP-II) and vCCL3 (vMIP-III) target the human but not the murine lymphotactin receptor. Virol J. 5:50. https:\/\/doi.org\/10.1186\/1743-422X-5-50","journal-title":"Virol J."},{"issue":"4","key":"11_CR212","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.1002\/1521-4141(200104)31:4<1217::AID-IMMU1217>3.0.CO;2-S","volume":"31","author":"HR Luttichau","year":"2001","unstructured":"Luttichau HR, Lewis IC, Gerstoft J, Schwartz TW (2001) The herpesvirus 8-encoded chemokine vMIP-II, but not the poxvirus-encoded chemokine MC148, inhibits the CCR10 receptor. Eur J Immunol 31(4):1217\u20131220. https:\/\/doi.org\/10.1002\/1521-4141(200104)31:4%3c1217:AID-IMMU1217%3e3.0.CO;2-S","journal-title":"Eur J Immunol"},{"issue":"24","key":"11_CR213","doi-asserted-by":"publisher","first-page":"17794","DOI":"10.1074\/jbc.M702001200","volume":"282","author":"HR Luttichau","year":"2007","unstructured":"Luttichau HR, Johnsen AH, Jurlander J, Rosenkilde MM, Schwartz TW (2007) Kaposi sarcoma-associated herpes virus targets the lymphotactin receptor with both a broad spectrum antagonist vCCL2 and a highly selective and potent agonist vCCL3. J Biol Chem 282(24):17794\u201317805. https:\/\/doi.org\/10.1074\/jbc.M702001200","journal-title":"J Biol Chem"},{"issue":"33","key":"11_CR214","doi-asserted-by":"publisher","first-page":"4842","DOI":"10.1038\/sj.onc.1210287","volume":"26","author":"X Ma","year":"2007","unstructured":"Ma X, Kalakonda S, Srinivasula SM, Reddy SP, Platanias LC, Kalvakolanu DV (2007) GRIM-19 associates with the serine protease HtrA2 for promoting cell death. Oncogene 26(33):4842\u20134849. https:\/\/doi.org\/10.1038\/sj.onc.1210287","journal-title":"Oncogene"},{"issue":"31","key":"11_CR215","doi-asserted-by":"publisher","first-page":"E4306","DOI":"10.1073\/pnas.1503831112","volume":"112","author":"Z Ma","year":"2015","unstructured":"Ma Z, Jacobs SR, West JA, Stopford C, Zhang Z, Davis Z et al (2015) Modulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses. Proc Natl Acad Sci U S A. 112(31):E4306\u2013E4315. https:\/\/doi.org\/10.1073\/pnas.1503831112","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"8\u20139","key":"11_CR216","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1515\/BC.2011.089","volume":"392","author":"Y Mandel-Gutfreund","year":"2011","unstructured":"Mandel-Gutfreund Y, Kosti I, Larisch S (2011) ARTS, the unusual septin: structural and functional aspects. Biol Chem 392(8\u20139):783\u2013790. https:\/\/doi.org\/10.1515\/BC.2011.089","journal-title":"Biol Chem"},{"issue":"3","key":"11_CR217","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1093\/emboj\/18.3.654","volume":"18","author":"DJ Mann","year":"1999","unstructured":"Mann DJ, Child ES, Swanton C, Laman H, Jones N (1999) Modulation of p27(Kip1) levels by the cyclin encoded by Kaposi\u2019s sarcoma-associated herpesvirus. EMBO J 18(3):654\u2013663. https:\/\/doi.org\/10.1093\/emboj\/18.3.654","journal-title":"EMBO J"},{"issue":"17","key":"11_CR218","doi-asserted-by":"publisher","first-page":"8849","DOI":"10.1128\/JVI.00339-09","volume":"83","author":"L Marcos-Villar","year":"2009","unstructured":"Marcos-Villar L, Lopitz-Otsoa F, Gallego P, Munoz-Fontela C, Gonzalez-Santamaria J, Campagna M et al (2009) Kaposi\u2019s sarcoma-associated herpesvirus protein LANA2 disrupts PML oncogenic domains and inhibits PML-mediated transcriptional repression of the survivin gene. J Virol 83(17):8849\u20138858. https:\/\/doi.org\/10.1128\/JVI.00339-09","journal-title":"J Virol"},{"issue":"4","key":"11_CR219","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1038\/onc.2012.603","volume":"33","author":"L Marcos-Villar","year":"2014","unstructured":"Marcos-Villar L, Gallego P, Munoz-Fontela C, de la Cruz-Herrera CF, Campagna M, Gonzalez D et al (2014) Kaposi\u2019s sarcoma-associated herpesvirus lana2 protein interacts with the pocket proteins and inhibits their sumoylation. Oncogene 33(4):495\u2013503. https:\/\/doi.org\/10.1038\/onc.2012.603","journal-title":"Oncogene"},{"issue":"4","key":"11_CR220","doi-asserted-by":"publisher","first-page":"e1006335","DOI":"10.1371\/journal.ppat.1006335","volume":"13","author":"G Mariggio","year":"2017","unstructured":"Mariggio G, Koch S, Zhang G, Weidner-Glunde M, Ruckert J, Kati S et al (2017) Kaposi sarcoma herpesvirus (KSHV) latency-associated nuclear antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency. PLoS Pathog 13(4):e1006335. https:\/\/doi.org\/10.1371\/journal.ppat.1006335","journal-title":"PLoS Pathog"},{"issue":"25","key":"11_CR221","doi-asserted-by":"publisher","first-page":"9399","DOI":"10.1073\/pnas.0308016101","volume":"101","author":"H Matta","year":"2004","unstructured":"Matta H, Chaudhary PM (2004) Activation of alternative NF-kappa B pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1 beta-converting enzyme inhibitory protein (vFLIP). Proc Natl Acad Sci U S A 101(25):9399\u20139404. https:\/\/doi.org\/10.1073\/pnas.0308016101","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"34","key":"11_CR222","doi-asserted-by":"publisher","first-page":"24858","DOI":"10.1074\/jbc.M700118200","volume":"282","author":"H Matta","year":"2007","unstructured":"Matta H, Mazzacurati L, Schamus S, Yang T, Sun Q, Chaudhary PM (2007) Kaposi\u2019s sarcoma-associated herpesvirus (KSHV) oncoprotein K13 bypasses TRAFs and directly interacts with the IkappaB kinase complex to selectively activate NF-kappaB without JNK activation. J Biol Chem 282(34):24858\u201324865. https:\/\/doi.org\/10.1074\/jbc.M700118200","journal-title":"J Biol Chem"},{"issue":"9","key":"11_CR223","doi-asserted-by":"publisher","first-page":"1250","DOI":"10.1086\/503052","volume":"193","author":"S Mbulaiteye","year":"2006","unstructured":"Mbulaiteye S, Marshall V, Bagni RK, Wang CD, Mbisa G, Bakaki PM et al (2006) Molecular evidence for mother-to-child transmission of Kaposi sarcoma-associated herpesvirus in Uganda and K1 gene evolution within the host. J Infect Dis 193(9):1250\u20131257. https:\/\/doi.org\/10.1086\/503052","journal-title":"J Infect Dis"},{"issue":"5710","key":"11_CR224","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1126\/science.1105779","volume":"307","author":"C McCormick","year":"2005","unstructured":"McCormick C, Ganem D (2005) The kaposin B protein of KSHV activates the p38\/MK2 pathway and stabilizes cytokine mRNAs. Science 307(5710):739\u2013741. https:\/\/doi.org\/10.1126\/science.1105779","journal-title":"Science"},{"issue":"12","key":"11_CR225","doi-asserted-by":"publisher","first-page":"6165","DOI":"10.1128\/JVI.02331-05","volume":"80","author":"C McCormick","year":"2006","unstructured":"McCormick C, Ganem D (2006) Phosphorylation and function of the kaposin B direct repeats of Kaposi\u2019s sarcoma-associated herpesvirus. J Virol 80(12):6165\u20136170. https:\/\/doi.org\/10.1128\/JVI.02331-05","journal-title":"J Virol"},{"issue":"10","key":"11_CR226","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1038\/nrc2888","volume":"10","author":"EA Mesri","year":"2010","unstructured":"Mesri EA, Cesarman E, Boshoff C (2010) Kaposi\u2019s sarcoma and its associated herpesvirus. Nat Rev Cancer 10(10):707\u2013719. https:\/\/doi.org\/10.1038\/nrc2888","journal-title":"Nat Rev Cancer"},{"issue":"11","key":"11_CR227","doi-asserted-by":"publisher","first-page":"4068","DOI":"10.1073\/pnas.87.11.4068","volume":"87","author":"SA Miles","year":"1990","unstructured":"Miles SA, Rezai AR, Salazar-Gonzalez JF, Vander Meyden M, Stevens RH, Logan DM et al (1990) AIDS Kaposi sarcoma-derived cells produce and respond to interleukin 6. Proc Natl Acad Sci U S A. 87(11):4068\u20134072","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"1","key":"11_CR228","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/S1535-6108(02)00237-4","volume":"3","author":"S Montaner","year":"2003","unstructured":"Montaner S, Sodhi A, Molinolo A, Bugge TH, Sawai ET, He Y et al (2003) Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi\u2019s sarcomagenesis and can promote the tumorigenic potential of viral latent genes. Cancer Cell 3(1):23\u201336","journal-title":"Cancer Cell"},{"issue":"9","key":"11_CR229","doi-asserted-by":"publisher","first-page":"2903","DOI":"10.1182\/blood-2003-12-4436","volume":"104","author":"S Montaner","year":"2004","unstructured":"Montaner S, Sodhi A, Servitja JM, Ramsdell AK, Barac A, Sawai ET et al (2004) The small GTPase Rac1 links the Kaposi sarcoma-associated herpesvirus vGPCR to cytokine secretion and paracrine neoplasia. Blood 104(9):2903\u20132911. https:\/\/doi.org\/10.1182\/blood-2003-12-4436","journal-title":"Blood"},{"issue":"5293","key":"11_CR230","doi-asserted-by":"publisher","first-page":"1739","DOI":"10.1126\/science.274.5293.1739","volume":"274","author":"PS Moore","year":"1996","unstructured":"Moore PS, Boshoff C, Weiss RA, Chang Y (1996) Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV. Science 274(5293):1739\u20131744","journal-title":"Science"},{"issue":"3","key":"11_CR231","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1002\/1096-9071(200007)61:3<332::AID-JMV8>3.0.CO;2-3","volume":"61","author":"Y Mori","year":"2000","unstructured":"Mori Y, Nishimoto N, Ohno M, Inagi R, Dhepakson P, Amou K et al (2000) Human herpesvirus 8-encoded interleukin-6 homologue (viral IL-6) induces endogenous human IL-6 secretion. J Med Virol 61(3):332\u2013335","journal-title":"J Med Virol"},{"issue":"1","key":"11_CR232","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.yexcr.2005.08.022","volume":"311","author":"C Munoz-Fontela","year":"2005","unstructured":"Munoz-Fontela C, Collado M, Rodriguez E, Garcia MA, Alvarez-Barrientos A, Arroyo J et al (2005) Identification of a nuclear export signal in the KSHV latent protein LANA2 mediating its export from the nucleus. Exp Cell Res 311(1):96\u2013105. https:\/\/doi.org\/10.1016\/j.yexcr.2005.08.022","journal-title":"Exp Cell Res"},{"issue":"3","key":"11_CR233","doi-asserted-by":"publisher","first-page":"1511","DOI":"10.1128\/JVI.01816-06","volume":"81","author":"C Munoz-Fontela","year":"2007","unstructured":"Munoz-Fontela C, Marcos-Villar L, Gallego P, Arroyo J, Da Costa M, Pomeranz KM et al (2007) Latent protein LANA2 from Kaposi\u2019s sarcoma-associated herpesvirus interacts with 14-3-3 proteins and inhibits FOXO3a transcription factor. J Virol 81(3):1511\u20131516. https:\/\/doi.org\/10.1128\/JVI.01816-06","journal-title":"J Virol"},{"issue":"6","key":"11_CR234","doi-asserted-by":"publisher","first-page":"4980","DOI":"10.1128\/JVI.72.6.4980-4988.1998","volume":"72","author":"S Muralidhar","year":"1998","unstructured":"Muralidhar S, Pumfery AM, Hassani M, Sadaie MR, Kishishita M, Brady JN et al (1998) Identification of kaposin (open reading frame K12) as a human herpesvirus 8 (Kaposi\u2019s sarcoma-associated herpesvirus) transforming gene. J Virol 72(6):4980\u20134988","journal-title":"J Virol"},{"issue":"3","key":"11_CR235","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/S1386-6532(99)00081-5","volume":"16","author":"S Muralidhar","year":"2000","unstructured":"Muralidhar S, Veytsmann G, Chandran B, Ablashi D, Doniger J, Rosenthal LJ (2000) Characterization of the human herpesvirus 8 (Kaposi\u2019s sarcoma-associated herpesvirus) oncogene, kaposin (ORF K12). J Clin Virol 16(3):203\u2013213","journal-title":"J Clin Virol"},{"issue":"8","key":"11_CR236","doi-asserted-by":"publisher","first-page":"3307","DOI":"10.1128\/jvi.63.8.3307-3314.1989","volume":"63","author":"SC Murthy","year":"1989","unstructured":"Murthy SC, Trimble JJ, Desrosiers RC (1989) Deletion mutants of herpesvirus saimiri define an open reading frame necessary for transformation. J Virol 63(8):3307\u20133314","journal-title":"J Virol"},{"issue":"Pt 10","key":"11_CR237","doi-asserted-by":"publisher","first-page":"2394","DOI":"10.1099\/vir.0.034322-0","volume":"92","author":"M Mutocheluh","year":"2011","unstructured":"Mutocheluh M, Hindle L, Areste C, Chanas SA, Butler LM, Lowry K et al (2011) Kaposi\u2019s sarcoma-associated herpesvirus viral interferon regulatory factor-2 inhibits type 1 interferon signalling by targeting interferon-stimulated gene factor-3. J Gen Virol 92(Pt 10):2394\u20132398. https:\/\/doi.org\/10.1099\/vir.0.034322-0","journal-title":"J Gen Virol"},{"issue":"4","key":"11_CR238","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/j.chom.2009.03.003","volume":"5","author":"D Nachmani","year":"2009","unstructured":"Nachmani D, Stern-Ginossar N, Sarid R, Mandelboim O (2009) Diverse herpesvirus microRNAs target the stress-induced immune ligand MICB to escape recognition by natural killer cells. Cell Host Microbe 5(4):376\u2013385. https:\/\/doi.org\/10.1016\/j.chom.2009.03.003","journal-title":"Cell Host Microbe"},{"issue":"16","key":"11_CR239","doi-asserted-by":"publisher","first-page":"7572","DOI":"10.1128\/JVI.75.16.7572-7582.2001","volume":"75","author":"H Nakamura","year":"2001","unstructured":"Nakamura H, Li M, Zarycki J, Jung JU (2001) Inhibition of p53 tumor suppressor by viral interferon regulatory factor. J Virol 75(16):7572\u20137582. https:\/\/doi.org\/10.1128\/JVI.75.16.7572-7582.2001","journal-title":"J Virol"},{"issue":"7","key":"11_CR240","doi-asserted-by":"publisher","first-page":"4205","DOI":"10.1128\/JVI.77.7.4205-4220.2003","volume":"77","author":"H Nakamura","year":"2003","unstructured":"Nakamura H, Lu M, Gwack Y, Souvlis J, Zeichner SL, Jung JU (2003) Global changes in Kaposi\u2019s sarcoma-associated virus gene expression patterns following expression of a tetracycline-inducible Rta transactivator. J Virol 77(7):4205\u20134220","journal-title":"J Virol"},{"issue":"5","key":"11_CR241","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1007\/s00705-002-0971-7","volume":"148","author":"K Nakano","year":"2003","unstructured":"Nakano K, Isegawa Y, Zou P, Tadagaki K, Inagi R, Yamanishi K (2003) Kaposi\u2019s sarcoma-associated herpesvirus (KSHV)-encoded vMIP-I and vMIP-II induce signal transduction and chemotaxis in monocytic cells. Arch Virol 148(5):871\u2013890. https:\/\/doi.org\/10.1007\/s00705-002-0971-7","journal-title":"Arch Virol"},{"issue":"16","key":"11_CR242","doi-asserted-by":"publisher","first-page":"2837","DOI":"10.1182\/blood-2013-01-479972","volume":"122","author":"U Nayar","year":"2013","unstructured":"Nayar U, Lu P, Goldstein RL, Vider J, Ballon G, Rodina A et al (2013) Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies. Blood 122(16):2837\u20132847. https:\/\/doi.org\/10.1182\/blood-2013-01-479972","journal-title":"Blood"},{"issue":"1","key":"11_CR243","doi-asserted-by":"publisher","first-page":"839","DOI":"10.1128\/jvi.71.1.839-842.1997","volume":"71","author":"F Neipel","year":"1997","unstructured":"Neipel F, Albrecht JC, Ensser A, Huang YQ, Li JJ, Friedman-Kien AE et al (1997a) Human herpesvirus 8 encodes a homolog of interleukin-6. J Virol 71(1):839\u2013842","journal-title":"J Virol"},{"issue":"6","key":"11_CR244","doi-asserted-by":"publisher","first-page":"4187","DOI":"10.1128\/jvi.71.6.4187-4192.1997","volume":"71","author":"F Neipel","year":"1997","unstructured":"Neipel F, Albrecht JC, Fleckenstein B (1997b) Cell-homologous genes in the Kaposi\u2019s sarcoma-associated rhadinovirus human herpesvirus 8: determinants of its pathogenicity? J Virol 71(6):4187\u20134192","journal-title":"J Virol"},{"issue":"7","key":"11_CR245","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1089\/jir.2005.25.373","volume":"25","author":"J Nicholas","year":"2005","unstructured":"Nicholas J (2005) Human gammaherpesvirus cytokines and chemokine receptors. J Interferon Cytokine Res 25(7):373\u2013383. https:\/\/doi.org\/10.1089\/jir.2005.25.373","journal-title":"J Interferon Cytokine Res"},{"issue":"3","key":"11_CR246","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1038\/nm0397-287","volume":"3","author":"J Nicholas","year":"1997","unstructured":"Nicholas J, Ruvolo VR, Burns WH, Sandford G, Wan X, Ciufo D et al (1997) Kaposi\u2019s sarcoma-associated human herpesvirus-8 encodes homologues of macrophage inflammatory protein-1 and interleukin-6. Nat Med 3(3):287\u2013292","journal-title":"Nat Med"},{"key":"11_CR247","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1093\/oxfordjournals.jncimonographs.a024179","volume":"23","author":"J Nicholas","year":"1998","unstructured":"Nicholas J, Zong JC, Alcendor DJ, Ciufo DM, Poole LJ, Sarisky RT et al (1998) Novel organizational features, captured cellular genes, and strain variability within the genome of KSHV\/HHV8. J Natl Cancer Inst Monogr. 23:79\u201388","journal-title":"J Natl Cancer Inst Monogr."},{"key":"11_CR248","first-page":"185","volume":"312","author":"MK Offermann","year":"2007","unstructured":"Offermann MK (2007) Kaposi sarcoma herpesvirus-encoded interferon regulator factors. Curr Top Microbiol Immunol 312:185\u2013209","journal-title":"Curr Top Microbiol Immunol"},{"issue":"2","key":"11_CR249","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1053\/beha.1999.0068","volume":"13","author":"M Okano","year":"2000","unstructured":"Okano M (2000) Haematological associations of Epstein-Barr virus infection. Baillieres Best Pract Res Clin Haematol. 13(2):199\u2013214. https:\/\/doi.org\/10.1053\/beha.1999.0068","journal-title":"Baillieres Best Pract Res Clin Haematol."},{"issue":"6","key":"11_CR250","doi-asserted-by":"publisher","first-page":"2069","DOI":"10.1182\/blood.V96.6.2069.h8002069_2069_2073","volume":"96","author":"E Oksenhendler","year":"2000","unstructured":"Oksenhendler E, Carcelain G, Aoki Y, Boulanger E, Maillard A, Clauvel JP et al (2000) High levels of human herpesvirus 8 viral load, human interleukin-6, interleukin-10, and C reactive protein correlate with exacerbation of multicentric castleman disease in HIV-infected patients. Blood 96(6):2069\u20132073","journal-title":"Blood"},{"issue":"22","key":"11_CR251","doi-asserted-by":"publisher","first-page":"12680","DOI":"10.1128\/JVI.00556-07","volume":"81","author":"J Park","year":"2007","unstructured":"Park J, Lee MS, Yoo SM, Jeong KW, Lee D, Choe J et al (2007) Identification of the DNA sequence interacting with Kaposi\u2019s sarcoma-associated herpesvirus viral interferon regulatory factor 1. J Virol 81(22):12680\u201312684. https:\/\/doi.org\/10.1128\/JVI.00556-07","journal-title":"J Virol"},{"issue":"18","key":"11_CR252","doi-asserted-by":"publisher","first-page":"8660","DOI":"10.1128\/JVI.75.18.8660-8673.2001","volume":"75","author":"S Pati","year":"2001","unstructured":"Pati S, Cavrois M, Guo HG, Foulke JS Jr, Kim J, Feldman RA et al (2001) Activation of NF-kappaB by the human herpesvirus 8 chemokine receptor ORF74: evidence for a paracrine model of Kaposi\u2019s sarcoma pathogenesis. J Virol 75(18):8660\u20138673","journal-title":"J Virol"},{"issue":"6","key":"11_CR253","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1016\/j.cell.2005.07.002","volume":"122","author":"S Pattingre","year":"2005","unstructured":"Pattingre S, Tassa A, Qu X, Garuti R, Liang XH, Mizushima N et al (2005) Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 122(6):927\u2013939. https:\/\/doi.org\/10.1016\/j.cell.2005.07.002","journal-title":"Cell"},{"issue":"3","key":"11_CR254","doi-asserted-by":"publisher","first-page":"1589","DOI":"10.1128\/JVI.05754-11","volume":"86","author":"N Paudel","year":"2012","unstructured":"Paudel N, Sadagopan S, Balasubramanian S, Chandran B (2012) Kaposi\u2019s sarcoma-associated herpesvirus latency-associated nuclear antigen and angiogenin interact with common host proteins, including annexin A2, which is essential for survival of latently infected cells. J Virol 86(3):1589\u20131607. https:\/\/doi.org\/10.1128\/JVI.05754-11","journal-title":"J Virol"},{"issue":"10","key":"11_CR255","doi-asserted-by":"publisher","first-page":"4843","DOI":"10.1128\/JVI.75.10.4843-4853.2001","volume":"75","author":"M Paulose-Murphy","year":"2001","unstructured":"Paulose-Murphy M, Ha NK, Xiang C, Chen Y, Gillim L, Yarchoan R et al (2001) Transcription program of human herpesvirus 8 (kaposi\u2019s sarcoma-associated herpesvirus). J Virol 75(10):4843\u20134853. https:\/\/doi.org\/10.1128\/JVI.75.10.4843-4853.2001","journal-title":"J Virol"},{"issue":"22","key":"11_CR256","doi-asserted-by":"publisher","first-page":"14457","DOI":"10.1128\/JVI.79.22.14457-14464.2005","volume":"79","author":"M Pearce","year":"2005","unstructured":"Pearce M, Matsumura S, Wilson AC (2005) Transcripts encoding K12, v-FLIP, v-cyclin, and the microRNA cluster of Kaposi\u2019s sarcoma-associated herpesvirus originate from a common promoter. J Virol 79(22):14457\u201314464. https:\/\/doi.org\/10.1128\/JVI.79.22.14457-14464.2005","journal-title":"J Virol"},{"issue":"4","key":"11_CR257","doi-asserted-by":"publisher","first-page":"1912","DOI":"10.1128\/JVI.01757-06","volume":"81","author":"CE Petre","year":"2007","unstructured":"Petre CE, Sin SH, Dittmer DP (2007) Functional p53 signaling in Kaposi\u2019s sarcoma-associated herpesvirus lymphomas: implications for therapy. J Virol 81(4):1912\u20131922. https:\/\/doi.org\/10.1128\/JVI.01757-06","journal-title":"J Virol"},{"issue":"5671","key":"11_CR258","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1126\/science.1096781","volume":"304","author":"S Pfeffer","year":"2004","unstructured":"Pfeffer S, Zavolan M, Grasser FA, Chien M, Russo JJ, Ju J et al (2004) Identification of virus-encoded microRNAs. Science 304(5671):734\u2013736. https:\/\/doi.org\/10.1126\/science.1096781","journal-title":"Science"},{"issue":"4","key":"11_CR259","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1038\/nmeth746","volume":"2","author":"S Pfeffer","year":"2005","unstructured":"Pfeffer S, Sewer A, Lagos-Quintana M, Sheridan R, Sander C, Grasser FA et al (2005) Identification of microRNAs of the herpesvirus family. Nat Methods 2(4):269\u2013276. https:\/\/doi.org\/10.1038\/nmeth746","journal-title":"Nat Methods"},{"issue":"2","key":"11_CR260","doi-asserted-by":"publisher","first-page":"1140","DOI":"10.1128\/JVI.01362-10","volume":"85","author":"N Philpott","year":"2011","unstructured":"Philpott N, Bakken T, Pennell C, Chen L, Wu J, Cannon M (2011) The Kaposi\u2019s sarcoma-associated herpesvirus G protein-coupled receptor contains an immunoreceptor tyrosine-based inhibitory motif that activates Shp2. J Virol 85(2):1140\u20131144. https:\/\/doi.org\/10.1128\/JVI.01362-10","journal-title":"J Virol"},{"issue":"16","key":"11_CR261","doi-asserted-by":"publisher","first-page":"8231","DOI":"10.1128\/JVI.01696-09","volume":"84","author":"M Pietrek","year":"2010","unstructured":"Pietrek M, Brinkmann MM, Glowacka I, Enlund A, Havemeier A, Dittrich-Breiholz O et al (2010) Role of the Kaposi\u2019s sarcoma-associated herpesvirus K15 SH3 binding site in inflammatory signaling and B-cell activation. J Virol 84(16):8231\u20138240. https:\/\/doi.org\/10.1128\/JVI.01696-09","journal-title":"J Virol"},{"issue":"10","key":"11_CR262","doi-asserted-by":"publisher","first-page":"4005","DOI":"10.3390\/v6104005","volume":"6","author":"K Plaisance-Bonstaff","year":"2014","unstructured":"Plaisance-Bonstaff K, Choi HS, Beals T, Krueger BJ, Boss IW, Gay LA et al (2014) KSHV miRNAs decrease expression of lytic genes in latently infected PEL and endothelial cells by targeting host transcription factors. Viruses. 6(10):4005\u20134023. https:\/\/doi.org\/10.3390\/v6104005","journal-title":"Viruses."},{"issue":"12","key":"11_CR263","doi-asserted-by":"publisher","first-page":"1823","DOI":"10.1038\/sj.onc.1205360","volume":"21","author":"G Platt","year":"2002","unstructured":"Platt G, Carbone A, Mittnacht S (2002) p16INK4a loss and sensitivity in KSHV associated primary effusion lymphoma. Oncogene 21(12):1823\u20131831. https:\/\/doi.org\/10.1038\/sj.onc.1205360","journal-title":"Oncogene"},{"key":"11_CR264","doi-asserted-by":"publisher","first-page":"73","DOI":"10.3389\/fmicb.2012.00073","volume":"3","author":"MN Polizzotto","year":"2012","unstructured":"Polizzotto MN, Uldrick TS, Hu D, Yarchoan R (2012) Clinical manifestations of Kaposi sarcoma herpesvirus lytic activation: multicentric castleman disease (KSHV-MCD) and the KSHV inflammatory cytokine syndrome. Front Microbiol 3:73. https:\/\/doi.org\/10.3389\/fmicb.2012.00073","journal-title":"Front Microbiol"},{"issue":"8","key":"11_CR265","doi-asserted-by":"publisher","first-page":"6646","DOI":"10.1128\/JVI.73.8.6646-6660.1999","volume":"73","author":"LJ Poole","year":"1999","unstructured":"Poole LJ, Zong JC, Ciufo DM, Alcendor DJ, Cannon JS, Ambinder R et al (1999) Comparison of genetic variability at multiple loci across the genomes of the major subtypes of Kaposi\u2019s sarcoma-associated herpesvirus reveals evidence for recombination and for two distinct types of open reading frame K15 alleles at the right-hand end. J Virol 73(8):6646\u20136660","journal-title":"J Virol"},{"issue":"12","key":"11_CR266","doi-asserted-by":"publisher","first-page":"6621","DOI":"10.1128\/JVI.78.12.6621-6635.2004","volume":"78","author":"VP Pozharskaya","year":"2004","unstructured":"Pozharskaya VP, Weakland LL, Zimring JC, Krug LT, Unger ER, Neisch A et al (2004) Short duration of elevated vIRF-1 expression during lytic replication of human herpesvirus 8 limits its ability to block antiviral responses induced by alpha interferon in BCBL-1 cells. J Virol 78(12):6621\u20136635. https:\/\/doi.org\/10.1128\/JVI.78.12.6621-6635.2004","journal-title":"J Virol"},{"issue":"12","key":"11_CR267","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1093\/jnci\/94.12.926","volume":"94","author":"O Prakash","year":"2002","unstructured":"Prakash O, Tang ZY, Peng X, Coleman R, Gill J, Farr G et al (2002) Tumorigenesis and aberrant signaling in transgenic mice expressing the human herpesvirus-8 K1 gene. J Natl Cancer Inst 94(12):926\u2013935","journal-title":"J Natl Cancer Inst"},{"issue":"12","key":"11_CR268","doi-asserted-by":"publisher","first-page":"1835","DOI":"10.1038\/onc.2009.460","volume":"29","author":"V Punj","year":"2010","unstructured":"Punj V, Matta H, Schamus S, Tamewitz A, Anyang B, Chaudhary PM (2010) Kaposi\u2019s sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 suppresses CXCR4 expression by upregulating miR-146a. Oncogene 29(12):1835\u20131844. https:\/\/doi.org\/10.1038\/onc.2009.460","journal-title":"Oncogene"},{"issue":"6","key":"11_CR269","doi-asserted-by":"publisher","first-page":"1262","DOI":"10.1002\/ijc.21969","volume":"119","author":"P Pyakurel","year":"2006","unstructured":"Pyakurel P, Pak F, Mwakigonja AR, Kaaya E, Heiden T, Biberfeld P (2006) Lymphatic and vascular origin of Kaposi\u2019s sarcoma spindle cells during tumor development. Int J Cancer 119(6):1262\u20131267. https:\/\/doi.org\/10.1002\/ijc.21969","journal-title":"Int J Cancer"},{"issue":"1","key":"11_CR270","doi-asserted-by":"publisher","first-page":"e1000742","DOI":"10.1371\/journal.ppat.1000742","volume":"6","author":"Z Qin","year":"2010","unstructured":"Qin Z, Freitas E, Sullivan R, Mohan S, Bacelieri R, Branch D et al (2010a) Upregulation of xCT by KSHV-encoded microRNAs facilitates KSHV dissemination and persistence in an environment of oxidative stress. PLoS Pathog 6(1):e1000742. https:\/\/doi.org\/10.1371\/journal.ppat.1000742","journal-title":"PLoS Pathog"},{"issue":"1","key":"11_CR271","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1189\/jlb.0409251","volume":"87","author":"Z Qin","year":"2010","unstructured":"Qin Z, Kearney P, Plaisance K, Parsons CH (2010b) Pivotal advance: Kaposi\u2019s sarcoma-associated herpesvirus (KSHV)-encoded microRNA specifically induce IL-6 and IL-10 secretion by macrophages and monocytes. J Leukoc Biol 87(1):25\u201334","journal-title":"J Leukoc Biol"},{"issue":"8","key":"11_CR272","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1016\/j.tim.2017.02.002","volume":"25","author":"J Qin","year":"2017","unstructured":"Qin J, Li W, Gao SJ, Lu C (2017) KSHV microRNAs: Tricks of the Devil. Trends Microbiol 25(8):648\u2013661. https:\/\/doi.org\/10.1016\/j.tim.2017.02.002","journal-title":"Trends Microbiol"},{"issue":"10","key":"11_CR273","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.1038\/80459","volume":"6","author":"SA Radkov","year":"2000","unstructured":"Radkov SA, Kellam P, Boshoff C (2000) The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells. Nat Med 6(10):1121\u20131127. https:\/\/doi.org\/10.1038\/80459","journal-title":"Nat Med"},{"issue":"8","key":"11_CR274","doi-asserted-by":"publisher","first-page":"4249","DOI":"10.1128\/JVI.03687-14","volume":"89","author":"D Ramalingam","year":"2015","unstructured":"Ramalingam D, Happel C, Ziegelbauer JM (2015) Kaposi\u2019s sarcoma-associated herpesvirus microRNAs repress breakpoint cluster region protein expression, enhance Rac1 activity, and increase in vitro angiogenesis. J Virol 89(8):4249\u20134261. https:\/\/doi.org\/10.1128\/JVI.03687-14","journal-title":"J Virol"},{"issue":"6","key":"11_CR275","doi-asserted-by":"publisher","first-page":"e39438","DOI":"10.1371\/journal.pone.0039438","volume":"7","author":"K Ritthipichai","year":"2012","unstructured":"Ritthipichai K, Nan Y, Bossis I, Zhang Y (2012) Viral FLICE inhibitory protein of rhesus monkey rhadinovirus inhibits apoptosis by enhancing autophagosome formation. PLoS ONE 7(6):e39438. https:\/\/doi.org\/10.1371\/journal.pone.0039438","journal-title":"PLoS ONE"},{"issue":"1","key":"11_CR276","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1128\/JVI.75.1.429-438.2001","volume":"75","author":"C Rivas","year":"2001","unstructured":"Rivas C, Thlick AE, Parravicini C, Moore PS, Chang Y (2001) Kaposi\u2019s sarcoma-associated herpesvirus LANA2 is a B-cell-specific latent viral protein that inhibits p53. J Virol 75(1):429\u2013438. https:\/\/doi.org\/10.1128\/JVI.75.1.429-438.2001","journal-title":"J Virol"},{"issue":"13","key":"11_CR277","doi-asserted-by":"publisher","first-page":"1582","DOI":"10.1038\/sj.onc.1204191","volume":"20","author":"MM Rosenkilde","year":"2001","unstructured":"Rosenkilde MM, Waldhoer M, Luttichau HR, Schwartz TW (2001) Virally encoded 7TM receptors. Oncogene 20(13):1582\u20131593. https:\/\/doi.org\/10.1038\/sj.onc.1204191","journal-title":"Oncogene"},{"issue":"3","key":"11_CR278","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1007\/BF01625423","volume":"117","author":"WK Roth","year":"1991","unstructured":"Roth WK (1991) HIV-associated Kaposi\u2019s sarcoma: new developments in epidemiology and molecular pathology. J Cancer Res Clin Oncol 117(3):186\u2013191","journal-title":"J Cancer Res Clin Oncol"},{"issue":"25","key":"11_CR279","doi-asserted-by":"publisher","first-page":"14862","DOI":"10.1073\/pnas.93.25.14862","volume":"93","author":"JJ Russo","year":"1996","unstructured":"Russo JJ, Bohenzky RA, Chien MC, Chen J, Yan M, Maddalena D et al (1996) Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8). Proc Natl Acad Sci U S A. 93(25):14862\u201314867","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"7","key":"11_CR280","doi-asserted-by":"publisher","first-page":"3342","DOI":"10.1128\/JVI.02052-08","volume":"83","author":"S Sadagopan","year":"2009","unstructured":"Sadagopan S, Sharma-Walia N, Veettil MV, Bottero V, Levine R, Vart RJ et al (2009) Kaposi\u2019s sarcoma-associated herpesvirus upregulates angiogenin during infection of human dermal microvascular endothelial cells, which induces 45S rRNA synthesis, antiapoptosis, cell proliferation, migration, and angiogenesis. J Virol 83(7):3342\u20133364. https:\/\/doi.org\/10.1128\/JVI.02052-08","journal-title":"J Virol"},{"issue":"6","key":"11_CR281","doi-asserted-by":"publisher","first-page":"2666","DOI":"10.1128\/JVI.01532-10","volume":"85","author":"S Sadagopan","year":"2011","unstructured":"Sadagopan S, Valiya Veettil M, Paudel N, Bottero V, Chandran B (2011) Kaposi\u2019s sarcoma-associated herpesvirus-induced angiogenin plays roles in latency via the phospholipase C gamma pathway: blocking angiogenin inhibits latent gene expression and induces the lytic cycle. J Virol 85(6):2666\u20132685. https:\/\/doi.org\/10.1128\/JVI.01532-10","journal-title":"J Virol"},{"issue":"46","key":"11_CR282","doi-asserted-by":"publisher","first-page":"4835","DOI":"10.1038\/onc.2011.648","volume":"31","author":"S Sadagopan","year":"2012","unstructured":"Sadagopan S, Veettil MV, Chakraborty S, Sharma-Walia N, Paudel N, Bottero V et al (2012) Angiogenin functionally interacts with p53 and regulates p53-mediated apoptosis and cell survival. Oncogene 31(46):4835\u20134847. https:\/\/doi.org\/10.1038\/onc.2011.648","journal-title":"Oncogene"},{"issue":"7","key":"11_CR283","doi-asserted-by":"publisher","first-page":"5722","DOI":"10.1128\/JVI.73.7.5722-5730.1999","volume":"73","author":"R Sadler","year":"1999","unstructured":"Sadler R, Wu L, Forghani B, Renne R, Zhong W, Herndier B et al (1999) A complex translational program generates multiple novel proteins from the latently expressed kaposin (K12) locus of Kaposi\u2019s sarcoma-associated herpesvirus. J Virol 73(7):5722\u20135730","journal-title":"J Virol"},{"issue":"14","key":"11_CR284","doi-asserted-by":"publisher","first-page":"7299","DOI":"10.1128\/JVI.78.14.7299-7310.2004","volume":"78","author":"S Sakakibara","year":"2004","unstructured":"Sakakibara S, Ueda K, Nishimura K, Do E, Ohsaki E, Okuno T et al (2004) Accumulation of heterochromatin components on the terminal repeat sequence of Kaposi\u2019s sarcoma-associated herpesvirus mediated by the latency-associated nuclear antigen. J Virol 78(14):7299\u20137310. https:\/\/doi.org\/10.1128\/JVI.78.14.7299-7310.2004","journal-title":"J Virol"},{"key":"11_CR285","first-page":"15","volume":"28","author":"F Samaniego","year":"2001","unstructured":"Samaniego F, Pati S, Karp JE, Prakash O, Bose D (2001) Human herpesvirus 8 K1-associated nuclear factor-kappa B-dependent promoter activity: role in Kaposi\u2019s sarcoma inflammation? J Natl Cancer Inst Monogr. 28:15\u201323","journal-title":"J Natl Cancer Inst Monogr."},{"issue":"14","key":"11_CR286","doi-asserted-by":"publisher","first-page":"9301","DOI":"10.1128\/JVI.79.14.9301-9305.2005","volume":"79","author":"MA Samols","year":"2005","unstructured":"Samols MA, Hu J, Skalsky RL, Renne R (2005) Cloning and identification of a microRNA cluster within the latency-associated region of Kaposi\u2019s sarcoma-associated herpesvirus. J Virol 79(14):9301\u20139305. https:\/\/doi.org\/10.1128\/JVI.79.14.9301-9305.2005","journal-title":"J Virol"},{"issue":"5","key":"11_CR287","doi-asserted-by":"publisher","first-page":"e65","DOI":"10.1371\/journal.ppat.0030065","volume":"3","author":"MA Samols","year":"2007","unstructured":"Samols MA, Skalsky RL, Maldonado AM, Riva A, Lopez MC, Baker HV et al (2007) Identification of cellular genes targeted by KSHV-encoded microRNAs. PLoS Pathog 3(5):e65. https:\/\/doi.org\/10.1371\/journal.ppat.0030065","journal-title":"PLoS Pathog"},{"issue":"24","key":"11_CR288","doi-asserted-by":"publisher","first-page":"13009","DOI":"10.1128\/JVI.01399-09","volume":"83","author":"G Sandford","year":"2009","unstructured":"Sandford G, Choi YB, Nicholas J (2009) Role of ORF74-encoded viral G protein-coupled receptor in human herpesvirus 8 lytic replication. J Virol 83(24):13009\u201313014. https:\/\/doi.org\/10.1128\/JVI.01399-09","journal-title":"J Virol"},{"issue":"2","key":"11_CR289","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1182\/blood-2005-06-2534","volume":"107","author":"G Sarek","year":"2006","unstructured":"Sarek G, Jarviluoma A, Ojala PM (2006) KSHV viral cyclin inactivates p27KIP1 through Ser10 and Thr187 phosphorylation in proliferating primary effusion lymphomas. Blood 107(2):725\u2013732. https:\/\/doi.org\/10.1182\/blood-2005-06-2534","journal-title":"Blood"},{"issue":"3","key":"11_CR290","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1038\/nm0397-293","volume":"3","author":"R Sarid","year":"1997","unstructured":"Sarid R, Sato T, Bohenzky RA, Russo JJ, Chang Y (1997) Kaposi\u2019s sarcoma-associated herpesvirus encodes a functional bcl-2 homologue. Nat Med 3(3):293\u2013298","journal-title":"Nat Med"},{"issue":"9","key":"11_CR291","doi-asserted-by":"publisher","first-page":"4530","DOI":"10.1128\/JVI.02123-10","volume":"85","author":"K Schmidt","year":"2011","unstructured":"Schmidt K, Wies E, Neipel F (2011) Kaposi\u2019s sarcoma-associated herpesvirus viral interferon regulatory factor 3 inhibits gamma interferon and major histocompatibility complex class II expression. J Virol 85(9):4530\u20134537. https:\/\/doi.org\/10.1128\/JVI.02123-10","journal-title":"J Virol"},{"issue":"1","key":"11_CR292","doi-asserted-by":"publisher","first-page":"505","DOI":"10.4049\/jimmunol.167.1.505","volume":"167","author":"M Schwarz","year":"2001","unstructured":"Schwarz M, Murphy PM (2001) Kaposi\u2019s sarcoma-associated herpesvirus G protein-coupled receptor constitutively activates NF-kappa B and induces proinflammatory cytokine and chemokine production via a C-terminal signaling determinant. J Immunol. 167(1):505\u2013513","journal-title":"J Immunol."},{"issue":"2","key":"11_CR293","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/S0092-8674(03)00759-1","volume":"115","author":"DS Schwarz","year":"2003","unstructured":"Schwarz DS, Hutvagner G, Du T, Xu Z, Aronin N, Zamore PD (2003) Asymmetry in the assembly of the RNAi enzyme complex. Cell 115(2):199\u2013208","journal-title":"Cell"},{"issue":"4","key":"11_CR294","doi-asserted-by":"publisher","first-page":"3040","DOI":"10.1128\/JVI.73.4.3040-3053.1999","volume":"73","author":"RP Searles","year":"1999","unstructured":"Searles RP, Bergquam EP, Axthelm MK, Wong SW (1999) Sequence and genomic analysis of a Rhesus macaque rhadinovirus with similarity to Kaposi\u2019s sarcoma-associated herpesvirus\/human herpesvirus 8. J Virol 73(4):3040\u20133053","journal-title":"J Virol"},{"issue":"19","key":"11_CR295","doi-asserted-by":"publisher","first-page":"2501","DOI":"10.1101\/gad.836800","volume":"14","author":"R Sears","year":"2000","unstructured":"Sears R, Nuckolls F, Haura E, Taya Y, Tamai K, Nevins JR (2000) Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev 14(19):2501\u20132514","journal-title":"Genes Dev"},{"issue":"1","key":"11_CR296","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1006\/bbrc.2000.2393","volume":"270","author":"T Seo","year":"2000","unstructured":"Seo T, Lee D, Lee B, Chung JH, Choe J (2000) Viral interferon regulatory factor 1 of Kaposi\u2019s sarcoma-associated herpesvirus (human herpesvirus 8) binds to, and inhibits transactivation of CREB-binding protein. Biochem Biophys Res Commun 270(1):23\u201327. https:\/\/doi.org\/10.1006\/bbrc.2000.2393","journal-title":"Biochem Biophys Res Commun"},{"issue":"13","key":"11_CR297","doi-asserted-by":"publisher","first-page":"6193","DOI":"10.1128\/JVI.75.13.6193-6198.2001","volume":"75","author":"T Seo","year":"2001","unstructured":"Seo T, Park J, Lee D, Hwang SG, Choe J (2001) Viral interferon regulatory factor 1 of Kaposi\u2019s sarcoma-associated herpesvirus binds to p53 and represses p53-dependent transcription and apoptosis. J Virol 75(13):6193\u20136198. https:\/\/doi.org\/10.1128\/JVI.75.13.6193-6198.2001","journal-title":"J Virol"},{"issue":"17","key":"11_CR298","doi-asserted-by":"publisher","first-page":"8797","DOI":"10.1128\/JVI.76.17.8797-8807.2002","volume":"76","author":"T Seo","year":"2002","unstructured":"Seo T, Lee D, Shim YS, Angell JE, Chidambaram NV, Kalvakolanu DV et al (2002) Viral interferon regulatory factor 1 of Kaposi\u2019s sarcoma-associated herpesvirus interacts with a cell death regulator, GRIM19, and inhibits interferon\/retinoic acid-induced cell death. J Virol 76(17):8797\u20138807","journal-title":"J Virol"},{"issue":"5","key":"11_CR299","doi-asserted-by":"publisher","first-page":"1738","DOI":"10.1158\/0008-5472.CAN-04-2374","volume":"65","author":"T Seo","year":"2005","unstructured":"Seo T, Park J, Choe J (2005) Kaposi\u2019s sarcoma-associated herpesvirus viral IFN regulatory factor 1 inhibits transforming growth factor-beta signaling. Cancer Res 65(5):1738\u20131747. https:\/\/doi.org\/10.1158\/0008-5472.CAN-04-2374","journal-title":"Cancer Res"},{"issue":"39","key":"11_CR300","doi-asserted-by":"publisher","first-page":"14554","DOI":"10.1073\/pnas.0604469103","volume":"103","author":"M Shamay","year":"2006","unstructured":"Shamay M, Krithivas A, Zhang J, Hayward SD (2006) Recruitment of the de novo DNA methyltransferase Dnmt3a by Kaposi\u2019s sarcoma-associated herpesvirus LANA. Proc Natl Acad Sci U S A. 103(39):14554\u201314559. https:\/\/doi.org\/10.1073\/pnas.0604469103","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"2","key":"11_CR301","doi-asserted-by":"publisher","first-page":"e1000777","DOI":"10.1371\/journal.ppat.1000777","volume":"6","author":"N Sharma-Walia","year":"2010","unstructured":"Sharma-Walia N, Paul AG, Bottero V, Sadagopan S, Veettil MV, Kerur N et al (2010) Kaposi\u2019s sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasion. PLoS Pathog 6(2):e1000777. https:\/\/doi.org\/10.1371\/journal.ppat.1000777","journal-title":"PLoS Pathog"},{"issue":"2","key":"11_CR302","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1128\/JVI.76.2.802-816.2002","volume":"76","author":"TV Sharp","year":"2002","unstructured":"Sharp TV, Wang HW, Koumi A, Hollyman D, Endo Y, Ye H et al (2002) K15 protein of Kaposi\u2019s sarcoma-associated herpesvirus is latently expressed and binds to HAX-1, a protein with antiapoptotic function. J Virol 76(2):802\u2013816","journal-title":"J Virol"},{"issue":"49","key":"11_CR303","doi-asserted-by":"publisher","first-page":"45979","DOI":"10.1074\/jbc.M104783200","volume":"276","author":"LW Shepard","year":"2001","unstructured":"Shepard LW, Yang M, Xie P, Browning DD, Voyno-Yasenetskaya T, Kozasa T et al (2001) Constitutive activation of NF-kappa B and secretion of interleukin-8 induced by the G protein-coupled receptor of Kaposi\u2019s sarcoma-associated herpesvirus involve G alpha(13) and RhoA. J Biol Chem 276(49):45979\u201345987. https:\/\/doi.org\/10.1074\/jbc.M104783200","journal-title":"J Biol Chem"},{"issue":"7","key":"11_CR304","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1158\/1541-7786.MCR-07-0072","volume":"5","author":"WS Shim","year":"2007","unstructured":"Shim WS, Ho IA, Wong PE (2007) Angiopoietin: a TIE(d) balance in tumor angiogenesis. Mol Cancer Res 5(7):655\u2013665. https:\/\/doi.org\/10.1158\/1541-7786.MCR-07-0072","journal-title":"Mol Cancer Res"},{"issue":"5","key":"11_CR305","doi-asserted-by":"publisher","first-page":"2257","DOI":"10.1128\/JVI.80.5.2257-2266.2006","volume":"80","author":"YC Shin","year":"2006","unstructured":"Shin YC, Nakamura H, Liang X, Feng P, Chang H, Kowalik TF et al (2006) Inhibition of the ATM\/p53 signal transduction pathway by Kaposi\u2019s sarcoma-associated herpesvirus interferon regulatory factor 1. J Virol 80(5):2257\u20132266. https:\/\/doi.org\/10.1128\/JVI.80.5.2257-2266.2006","journal-title":"J Virol"},{"issue":"6","key":"11_CR306","doi-asserted-by":"publisher","first-page":"1751","DOI":"10.1158\/0008-5472.CAN-07-2766","volume":"68","author":"YC Shin","year":"2008","unstructured":"Shin YC, Joo CH, Gack MU, Lee HR, Jung JU (2008) Kaposi\u2019s sarcoma-associated herpesvirus viral IFN regulatory factor 3 stabilizes hypoxia-inducible factor-1 alpha to induce vascular endothelial growth factor expression. Cancer Res 68(6):1751\u20131759. https:\/\/doi.org\/10.1158\/0008-5472.CAN-07-2766","journal-title":"Cancer Res"},{"issue":"23","key":"11_CR307","doi-asserted-by":"publisher","first-page":"12836","DOI":"10.1128\/JVI.01804-07","volume":"81","author":"RL Skalsky","year":"2007","unstructured":"Skalsky RL, Samols MA, Plaisance KB, Boss IW, Riva A, Lopez MC et al (2007) Kaposi\u2019s sarcoma-associated herpesvirus encodes an ortholog of miR-155. J Virol 81(23):12836\u201312845. https:\/\/doi.org\/10.1128\/JVI.01804-07","journal-title":"J Virol"},{"key":"11_CR308","doi-asserted-by":"publisher","unstructured":"Smith CG, Kharkwal H, Wilson DW (2017) Expression and subcellular localization of the Kaposi\u2019s sarcoma-associated herpesvirus K15P protein during latency and lytic reactivation in primary effusion lymphoma cells. J Virol 91(21). https:\/\/doi.org\/10.1128\/jvi.01370-17","DOI":"10.1128\/jvi.01370-17"},{"issue":"1","key":"11_CR309","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1128\/jvi.71.1.715-719.1997","volume":"71","author":"KA Staskus","year":"1997","unstructured":"Staskus KA, Zhong W, Gebhard K, Herndier B, Wang H, Renne R et al (1997) Kaposi\u2019s sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cells. J Virol 71(1):715\u2013719","journal-title":"J Virol"},{"issue":"5836","key":"11_CR310","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1126\/science.1140956","volume":"317","author":"N Stern-Ginossar","year":"2007","unstructured":"Stern-Ginossar N, Elefant N, Zimmermann A, Wolf DG, Saleh N, Biton M et al (2007) Host immune system gene targeting by a viral miRNA. Science 317(5836):376\u2013381. https:\/\/doi.org\/10.1126\/science.1140956","journal-title":"Science"},{"issue":"9","key":"11_CR311","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1038\/ni.1642","volume":"9","author":"N Stern-Ginossar","year":"2008","unstructured":"Stern-Ginossar N, Gur C, Biton M, Horwitz E, Elboim M, Stanietsky N et al (2008) Human microRNAs regulate stress-induced immune responses mediated by the receptor NKG2D. Nat Immunol 9(9):1065\u20131073. https:\/\/doi.org\/10.1038\/ni.1642","journal-title":"Nat Immunol"},{"issue":"4","key":"11_CR312","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1182\/blood.V95.4.1151.004k37_1151_1157","volume":"95","author":"JT Stine","year":"2000","unstructured":"Stine JT, Wood C, Hill M, Epp A, Raport CJ, Schweickart VL et al (2000) KSHV-encoded CC chemokine vMIP-III is a CCR4 agonist, stimulates angiogenesis, and selectively chemoattracts TH2 cells. Blood 95(4):1151\u20131157","journal-title":"Blood"},{"issue":"1","key":"11_CR313","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1002\/(SICI)1097-0215(19970703)72:1<68::AID-IJC10>3.0.CO;2-6","volume":"72","author":"M Sturzl","year":"1997","unstructured":"Sturzl M, Blasig C, Schreier A, Neipel F, Hohenadl C, Cornali E et al (1997) Expression of HHV-8 latency-associated T0.7 RNA in spindle cells and endothelial cells of AIDS-associated, classical and African Kaposi\u2019s sarcoma. Int J Cancer 72(1):68\u201371","journal-title":"Int J Cancer"},{"issue":"3","key":"11_CR314","doi-asserted-by":"publisher","first-page":"2232","DOI":"10.1128\/JVI.73.3.2232-2242.1999","volume":"73","author":"R Sun","year":"1999","unstructured":"Sun R, Lin SF, Staskus K, Gradoville L, Grogan E, Haase A et al (1999) Kinetics of Kaposi\u2019s sarcoma-associated herpesvirus gene expression. J Virol 73(3):2232\u20132242","journal-title":"J Virol"},{"issue":"19","key":"11_CR315","doi-asserted-by":"publisher","first-page":"2717","DOI":"10.1038\/sj.onc.1209298","volume":"25","author":"Q Sun","year":"2006","unstructured":"Sun Q, Matta H, Lu G, Chaudhary PM (2006) Induction of IL-8 expression by human herpesvirus 8 encoded vFLIP K13 via NF-kappaB activation. Oncogene 25(19):2717\u20132726. https:\/\/doi.org\/10.1038\/sj.onc.1209298","journal-title":"Oncogene"},{"issue":"13","key":"11_CR316","doi-asserted-by":"publisher","first-page":"7367","DOI":"10.1128\/JVI.00554-14","volume":"88","author":"Z Sun","year":"2014","unstructured":"Sun Z, Xiao B, Jha HC, Lu J, Banerjee S, Robertson ES (2014) Kaposi\u2019s sarcoma-associated herpesvirus-encoded LANA can induce chromosomal instability through targeted degradation of the mitotic checkpoint kinase Bub1. J Virol 88(13):7367\u20137378. https:\/\/doi.org\/10.1128\/JVI.00554-14","journal-title":"J Virol"},{"key":"11_CR317","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.bcp.2016.05.012","volume":"114","author":"M Szpakowska","year":"2016","unstructured":"Szpakowska M, Dupuis N, Baragli A, Counson M, Hanson J, Piette J et al (2016) Human herpesvirus 8-encoded chemokine vCCL2\/vMIP-II is an agonist of the atypical chemokine receptor ACKR3\/CXCR7. Biochem Pharmacol 114:14\u201321. https:\/\/doi.org\/10.1016\/j.bcp.2016.05.012","journal-title":"Biochem Pharmacol"},{"issue":"6685","key":"11_CR318","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1038\/31261","volume":"393","author":"K Tachibana","year":"1998","unstructured":"Tachibana K, Hirota S, Iizasa H, Yoshida H, Kawabata K, Kataoka Y et al (1998) The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. Nature 393(6685):591\u2013594. https:\/\/doi.org\/10.1038\/31261","journal-title":"Nature"},{"issue":"3","key":"11_CR319","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1111\/j.1349-7006.2007.00720.x","volume":"99","author":"A Takaoka","year":"2008","unstructured":"Takaoka A, Tamura T, Taniguchi T (2008) Interferon regulatory factor family of transcription factors and regulation of oncogenesis. Cancer Sci 99(3):467\u2013478. https:\/\/doi.org\/10.1111\/j.1349-7006.2007.00720.x","journal-title":"Cancer Sci"},{"issue":"1","key":"11_CR320","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.18632\/oncotarget.23456","volume":"9","author":"S Thakker","year":"2018","unstructured":"Thakker S, Strahan RC, Scurry AN, Uppal T, Verma SC (2018) KSHV LANA upregulates the expression of epidermal growth factor like domain 7 to promote angiogenesis. Oncotarget. 9(1):1210\u20131228. https:\/\/doi.org\/10.18632\/oncotarget.23456","journal-title":"Oncotarget."},{"issue":"2","key":"11_CR321","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1007\/s10456-009-9147-3","volume":"12","author":"M Thomas","year":"2009","unstructured":"Thomas M, Augustin HG (2009) The role of the Angiopoietins in vascular morphogenesis. Angiogenesis 12(2):125\u2013137. https:\/\/doi.org\/10.1007\/s10456-009-9147-3","journal-title":"Angiogenesis"},{"issue":"6624","key":"11_CR322","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1038\/386517a0","volume":"386","author":"M Thome","year":"1997","unstructured":"Thome M, Schneider P, Hofmann K, Fickenscher H, Meinl E, Neipel F et al (1997) Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors. Nature 386(6624):517\u2013521. https:\/\/doi.org\/10.1038\/386517a0","journal-title":"Nature"},{"issue":"3","key":"11_CR323","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1089\/10445490252925413","volume":"21","author":"B Tomkowicz","year":"2002","unstructured":"Tomkowicz B, Singh SP, Cartas M, Srinivasan A (2002) Human herpesvirus-8 encoded Kaposin: subcellular localization using immunofluorescence and biochemical approaches. DNA Cell Biol 21(3):151\u2013162. https:\/\/doi.org\/10.1089\/10445490252925413","journal-title":"DNA Cell Biol"},{"issue":"1","key":"11_CR324","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1089\/dna.2005.24.10","volume":"24","author":"B Tomkowicz","year":"2005","unstructured":"Tomkowicz B, Singh SP, Lai D, Singh A, Mahalingham S, Joseph J et al (2005) Mutational analysis reveals an essential role for the LXXLL motif in the transformation function of the human herpesvirus-8 oncoprotein, kaposin. DNA Cell Biol 24(1):10\u201320. https:\/\/doi.org\/10.1089\/dna.2005.24.10","journal-title":"DNA Cell Biol"},{"issue":"4","key":"11_CR325","doi-asserted-by":"publisher","first-page":"1918","DOI":"10.1128\/JVI.78.4.1918-1927.2004","volume":"78","author":"CC Tomlinson","year":"2004","unstructured":"Tomlinson CC, Damania B (2004) The K1 protein of Kaposi\u2019s sarcoma-associated herpesvirus activates the Akt signaling pathway. J Virol 78(4):1918\u20131927","journal-title":"J Virol"},{"issue":"2","key":"11_CR326","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1128\/JVI.00869-08","volume":"83","author":"YH Tsai","year":"2009","unstructured":"Tsai YH, Wu MF, Wu YH, Chang SJ, Lin SF, Sharp TV et al (2009) The M type K15 protein of Kaposi\u2019s sarcoma-associated herpesvirus regulates microRNA expression via its SH2-binding motif to induce cell migration and invasion. J Virol 83(2):622\u2013632. https:\/\/doi.org\/10.1128\/JVI.00869-08","journal-title":"J Virol"},{"issue":"2","key":"11_CR327","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1128\/JVI.02013-09","volume":"84","author":"JL Umbach","year":"2010","unstructured":"Umbach JL, Cullen BR (2010) In-depth analysis of Kaposi\u2019s sarcoma-associated herpesvirus microRNA expression provides insights into the mammalian microRNA-processing machinery. J Virol 84(2):695\u2013703. https:\/\/doi.org\/10.1128\/JVI.02013-09","journal-title":"J Virol"},{"key":"11_CR328","first-page":"101","volume":"312","author":"SC Verma","year":"2007","unstructured":"Verma SC, Lan K, Robertson E (2007) Structure and function of latency-associated nuclear antigen. Curr Top Microbiol Immunol 312:101\u2013136","journal-title":"Curr Top Microbiol Immunol"},{"issue":"3","key":"11_CR329","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/S1535-6108(02)00123-X","volume":"2","author":"EW s","year":"2002","unstructured":"Verschuren EW, Klefstrom J, Evan GI, Jones N (2002) The oncogenic potential of Kaposi\u2019s sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo. Cancer Cell 2(3):229\u2013241","journal-title":"Cancer Cell"},{"issue":"Pt 6","key":"11_CR330","doi-asserted-by":"publisher","first-page":"1347","DOI":"10.1099\/vir.0.79812-0","volume":"85","author":"EW Verschuren","year":"2004","unstructured":"Verschuren EW, Jones N, Evan GI (2004a) The cell cycle and how it is steered by Kaposi\u2019s sarcoma-associated herpesvirus cyclin. J Gen Virol 85(Pt 6):1347\u20131361. https:\/\/doi.org\/10.1099\/vir.0.79812-0","journal-title":"J Gen Virol"},{"issue":"2","key":"11_CR331","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1158\/0008-5472.CAN-03-1863","volume":"64","author":"EW Verschuren","year":"2004","unstructured":"Verschuren EW, Hodgson JG, Gray JW, Kogan S, Jones N, Evan GI (2004b) The role of p53 in suppression of KSHV cyclin-induced lymphomagenesis. Cancer Res 64(2):581\u2013589","journal-title":"Cancer Res"},{"issue":"7","key":"11_CR332","doi-asserted-by":"publisher","first-page":"3343","DOI":"10.1128\/JVI.78.7.3343-3351.2004","volume":"78","author":"D Verzijl","year":"2004","unstructured":"Verzijl D, Fitzsimons CP, Van Dijk M, Stewart JP, Timmerman H, Smit MJ et al (2004) Differential activation of murine herpesvirus 68- and Kaposi\u2019s sarcoma-associated herpesvirus-encoded ORF74 G protein-coupled receptors by human and murine chemokines. J Virol 78(7):3343\u20133351","journal-title":"J Virol"},{"issue":"1","key":"11_CR334","doi-asserted-by":"publisher","first-page":"3203","DOI":"10.1038\/s41467-019-11164-2","volume":"10","author":"MT Vo","year":"2019","unstructured":"Vo MT, Smith BJ, Nicholas J, Choi YB (2019) Activation of NIX-mediated mitophagy by an interferon regulatory factor homologue of human herpesvirus. Nat Commun. 10(1):3203. https:\/\/doi.org\/10.1038\/s41467-019-11164-2","journal-title":"Nat Commun."},{"issue":"11","key":"11_CR335","doi-asserted-by":"publisher","first-page":"2602","DOI":"10.1093\/emboj\/21.11.2602","volume":"21","author":"HW Wang","year":"2002","unstructured":"Wang HW, Sharp TV, Koumi A, Koentges G, Boshoff C (2002) Characterization of an anti-apoptotic glycoprotein encoded by Kaposi\u2019s sarcoma-associated herpesvirus which resembles a spliced variant of human survivin. EMBO J 21(11):2602\u20132615. https:\/\/doi.org\/10.1093\/emboj\/21.11.2602","journal-title":"EMBO J"},{"issue":"7","key":"11_CR336","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1038\/ng1384","volume":"36","author":"HW Wang","year":"2004","unstructured":"Wang HW, Trotter MW, Lagos D, Bourboulia D, Henderson S, Makinen T et al (2004) Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma. Nat Genet 36(7):687\u2013693. https:\/\/doi.org\/10.1038\/ng1384","journal-title":"Nat Genet"},{"issue":"7","key":"11_CR337","doi-asserted-by":"publisher","first-page":"3658","DOI":"10.1158\/0008-5472.CAN-05-3680","volume":"66","author":"L Wang","year":"2006","unstructured":"Wang L, Dittmer DP, Tomlinson CC, Fakhari FD, Damania B (2006) Immortalization of primary endothelial cells by the K1 protein of Kaposi\u2019s sarcoma-associated herpesvirus. Cancer Res 66(7):3658\u20133666. https:\/\/doi.org\/10.1158\/0008-5472.CAN-05-3680","journal-title":"Cancer Res"},{"issue":"4","key":"11_CR338","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1159\/000332402","volume":"35","author":"HR Wang","year":"2012","unstructured":"Wang HR, Chen DL, Zhao M, Shu SW, Xiong SX, Gan XD et al (2012) C-reactive protein induces interleukin-6 and thrombospondin-1 protein and mRNA expression through activation of nuclear factor-kB in HK-2 cells. Kidney Blood Press Res. 35(4):211\u2013219. https:\/\/doi.org\/10.1159\/000332402","journal-title":"Kidney Blood Press Res."},{"issue":"8","key":"11_CR339","doi-asserted-by":"publisher","first-page":"2458","DOI":"10.1002\/1521-4141(200108)31:8<2458::AID-IMMU2458>3.0.CO;2-L","volume":"31","author":"KS Weber","year":"2001","unstructured":"Weber KS, Grone HJ, Rocken M, Klier C, Gu S, Wank R et al (2001) Selective recruitment of Th2-type cells and evasion from a cytotoxic immune response mediated by viral macrophage inhibitory protein-II. Eur J Immunol 31(8):2458\u20132466. https:\/\/doi.org\/10.1002\/1521-4141(200108)31:8%3c2458:AID-IMMU2458%3e3.0.CO;2-L","journal-title":"Eur J Immunol"},{"issue":"Pt 1","key":"11_CR340","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1099\/vir.0.19465-0","volume":"85","author":"D Whitby","year":"2004","unstructured":"Whitby D, Marshall VA, Bagni RK, Wang CD, Gamache CJ, Guzman JR et al (2004) Genotypic characterization of Kaposi\u2019s sarcoma-associated herpesvirus in asymptomatic infected subjects from isolated populations. J Gen Virol 85(Pt 1):155\u2013163. https:\/\/doi.org\/10.1099\/vir.0.19465-0","journal-title":"J Gen Virol"},{"issue":"1","key":"11_CR341","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1182\/blood-2007-05-092288","volume":"111","author":"E Wies","year":"2008","unstructured":"Wies E, Mori Y, Hahn A, Kremmer E, Sturzl M, Fleckenstein B et al (2008) The viral interferon-regulatory factor-3 is required for the survival of KSHV-infected primary effusion lymphoma cells. Blood 111(1):320\u2013327. https:\/\/doi.org\/10.1182\/blood-2007-05-092288","journal-title":"Blood"},{"issue":"13","key":"11_CR342","doi-asserted-by":"publisher","first-page":"8525","DOI":"10.1074\/jbc.M809252200","volume":"284","author":"E Wies","year":"2009","unstructured":"Wies E, Hahn AS, Schmidt K, Viebahn C, Rohland N, Lux A et al (2009) The Kaposi\u2019s sarcoma-associated herpesvirus-encoded vIRF-3 inhibits cellular IRF-5. J Biol Chem 284(13):8525\u20138538. https:\/\/doi.org\/10.1074\/jbc.M809252200","journal-title":"J Biol Chem"},{"issue":"6","key":"11_CR343","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1016\/j.ceb.2005.10.001","volume":"17","author":"SN Willis","year":"2005","unstructured":"Willis SN, Adams JM (2005) Life in the balance: how BH3-only proteins induce apoptosis. Curr Opin Cell Biol 17(6):617\u2013625. https:\/\/doi.org\/10.1016\/j.ceb.2005.10.001","journal-title":"Curr Opin Cell Biol"},{"issue":"3","key":"11_CR344","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.1128\/JVI.80.3.1385-1392.2006","volume":"80","author":"EL Wong","year":"2006","unstructured":"Wong EL, Damania B (2006) Transcriptional regulation of the Kaposi\u2019s sarcoma-associated herpesvirus K15 gene. J Virol 80(3):1385\u20131392. https:\/\/doi.org\/10.1128\/JVI.80.3.1385-1392.2006","journal-title":"J Virol"},{"issue":"2","key":"11_CR345","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1128\/JVI.00694-11","volume":"86","author":"X Xi","year":"2012","unstructured":"Xi X, Persson LM, O\u2019Brien MW, Mohr I, Wilson AC (2012) Cooperation between viral interferon regulatory factor 4 and RTA to activate a subset of Kaposi\u2019s sarcoma-associated herpesvirus lytic promoters. J Virol 86(2):1021\u20131033. https:\/\/doi.org\/10.1128\/JVI.00694-11","journal-title":"J Virol"},{"key":"11_CR346","doi-asserted-by":"publisher","unstructured":"Xiang Q, Ju H, Li Q, Mei SC, Chen D, Choi YB et al (2018) Human herpesvirus 8 interferon regulatory factors 1 and 3 mediate replication and latency activities via interactions with USP7 deubiquitinase. J Virol 92(7). https:\/\/doi.org\/10.1128\/jvi.02003-17","DOI":"10.1128\/jvi.02003-17"},{"issue":"3","key":"11_CR347","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1084\/jem.191.3.445","volume":"191","author":"TY Yang","year":"2000","unstructured":"Yang TY, Chen SC, Leach MW, Manfra D, Homey B, Wiekowski M et al (2000) Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi\u2019s sarcoma. J Exp Med 191(3):445\u2013454","journal-title":"J Exp Med"},{"issue":"8","key":"11_CR348","doi-asserted-by":"publisher","first-page":"e1001046","DOI":"10.1371\/journal.ppat.1001046","volume":"6","author":"J Yoo","year":"2010","unstructured":"Yoo J, Kang J, Lee HN, Aguilar B, Kafka D, Lee S et al (2010) Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi\u2019s sarcoma herpes virus. PLoS Pathog 6(8):e1001046. https:\/\/doi.org\/10.1371\/journal.ppat.1001046","journal-title":"PLoS Pathog"},{"issue":"4","key":"11_CR349","doi-asserted-by":"publisher","first-page":"1360","DOI":"10.1182\/blood.V74.4.1360.1360","volume":"74","author":"K Yoshizaki","year":"1989","unstructured":"Yoshizaki K, Matsuda T, Nishimoto N, Kuritani T, Taeho L, Aozasa K et al (1989) Pathogenic significance of interleukin-6 (IL-6\/BSF-2) in Castleman\u2019s disease. Blood 74(4):1360\u20131367","journal-title":"Blood"},{"issue":"33","key":"11_CR350","doi-asserted-by":"publisher","first-page":"5108","DOI":"10.1038\/sj.onc.1206556","volume":"22","author":"LS Young","year":"2003","unstructured":"Young LS, Murray PG (2003) Epstein-Barr virus and oncogenesis: from latent genes to tumours. Oncogene 22(33):5108\u20135121. https:\/\/doi.org\/10.1038\/sj.onc.1206556","journal-title":"Oncogene"},{"issue":"17","key":"11_CR351","doi-asserted-by":"publisher","first-page":"9779","DOI":"10.1073\/pnas.1630797100","volume":"100","author":"Y Zeng","year":"2003","unstructured":"Zeng Y, Yi R, Cullen BR (2003) MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc Natl Acad Sci U S A. 100(17):9779\u20139784. https:\/\/doi.org\/10.1073\/pnas.1630797100","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"3","key":"11_CR352","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1158\/1535-7163.MCT-07-2036","volume":"7","author":"YJ Zhang","year":"2008","unstructured":"Zhang YJ, Bonaparte RS, Patel D, Stein DA, Iversen PL (2008) Blockade of viral interleukin-6 expression of Kaposi\u2019s sarcoma-associated herpesvirus. Mol Cancer Ther 7(3):712\u2013720. https:\/\/doi.org\/10.1158\/1535-7163.MCT-07-2036","journal-title":"Mol Cancer Ther"},{"issue":"8","key":"11_CR353","doi-asserted-by":"publisher","first-page":"E1034","DOI":"10.1073\/pnas.1516812113","volume":"113","author":"G Zhang","year":"2016","unstructured":"Zhang G, Chan B, Samarina N, Abere B, Weidner-Glunde M, Buch A et al (2016a) Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS. Proc Natl Acad Sci U S A. 113(8):E1034\u2013E1043. https:\/\/doi.org\/10.1073\/pnas.1516812113","journal-title":"Proc Natl Acad Sci U S A."},{"issue":"17","key":"11_CR354","doi-asserted-by":"publisher","first-page":"7657","DOI":"10.1128\/JVI.03102-15","volume":"90","author":"Z Zhang","year":"2016","unstructured":"Zhang Z, Chen W, Sanders MK, Brulois KF, Dittmer DP, Damania B (2016b) The K1 protein of Kaposi\u2019s sarcoma-associated herpesvirus augments viral lytic replication. J Virol 90(17):7657\u20137666. https:\/\/doi.org\/10.1128\/JVI.03102-15","journal-title":"J Virol"},{"issue":"10","key":"11_CR355","doi-asserted-by":"publisher","first-page":"e1067","DOI":"10.1371\/journal.pone.0001067","volume":"2","author":"J Zhao","year":"2007","unstructured":"Zhao J, Punj V, Matta H, Mazzacurati L, Schamus S, Yang Y et al (2007) K13 blocks KSHV lytic replication and deregulates vIL6 and hIL6 expression: a model of lytic replication induced clonal selection in viral oncogenesis. PLoS ONE 2(10):e1067. https:\/\/doi.org\/10.1371\/journal.pone.0001067","journal-title":"PLoS ONE"},{"issue":"13","key":"11_CR356","doi-asserted-by":"publisher","first-page":"6641","DOI":"10.1073\/pnas.93.13.6641","volume":"93","author":"W Zhong","year":"1996","unstructured":"Zhong W, Wang H, Herndier B, Ganem D (1996) Restricted expression of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi sarcoma. Proc Natl Acad Sci U S A. 93(13):6641\u20136646","journal-title":"Proc Natl Acad Sci U S A."},{"key":"11_CR357","doi-asserted-by":"publisher","unstructured":"Zhu Y, Ramos da Silva S, He M, Liang Q, Lu C, Feng P et al (2016) An oncogenic virus promotes cell survival and cellular transformation by suppressing glycolysis. PLoS Pathog 12(5):e1005648. https:\/\/doi.org\/10.1371\/journal.ppat.1005648","DOI":"10.1371\/journal.ppat.1005648"},{"issue":"2","key":"11_CR358","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/j.cbi.2010.06.012","volume":"188","author":"D Ziech","year":"2010","unstructured":"Ziech D, Franco R, Pappa A, Malamou-Mitsi V, Georgakila S, Georgakilas AG et al (2010) The role of epigenetics in environmental and occupational carcinogenesis. Chem Biol Interact 188(2):340\u2013349. https:\/\/doi.org\/10.1016\/j.cbi.2010.06.012","journal-title":"Chem Biol Interact"},{"issue":"1","key":"11_CR359","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1038\/ng.266","volume":"41","author":"JM Ziegelbauer","year":"2009","unstructured":"Ziegelbauer JM, Sullivan CS, Ganem D (2009) Tandem array-based expression screens identify host mRNA targets of virus-encoded microRNAs. Nat Genet 41(1):130\u2013134. https:\/\/doi.org\/10.1038\/ng.266","journal-title":"Nat Genet"},{"issue":"1","key":"11_CR360","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1128\/JVI.72.1.701-707.1998","volume":"72","author":"JC Zimring","year":"1998","unstructured":"Zimring JC, Goodbourn S, Offermann MK (1998) Human herpesvirus 8 encodes an interferon regulatory factor (IRF) homolog that represses IRF-1-mediated transcription. J Virol 72(1):701\u2013707","journal-title":"J Virol"},{"issue":"5","key":"11_CR361","doi-asserted-by":"publisher","first-page":"4156","DOI":"10.1128\/JVI.73.5.4156-4170.1999","volume":"73","author":"JC Zong","year":"1999","unstructured":"Zong JC, Ciufo DM, Alcendor DJ, Wan X, Nicholas J, Browning PJ et al (1999) High-level variability in the ORF-K1 membrane protein gene at the left end of the Kaposi\u2019s sarcoma-associated herpesvirus genome defines four major virus subtypes and multiple variants or clades in different human populations. J Virol 73(5):4156\u20134170","journal-title":"J Virol"}],"container-title":["Recent Results in Cancer Research","Viruses and Human Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-030-57362-1_11","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,27]],"date-time":"2023-01-27T01:06:31Z","timestamp":1674781591000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-030-57362-1_11"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,18]]},"ISBN":["9783030573614","9783030573621"],"references-count":360,"URL":"https:\/\/doi.org\/10.1007\/978-3-030-57362-1_11","relation":{},"ISSN":["0080-0015","2197-6767"],"issn-type":[{"value":"0080-0015","type":"print"},{"value":"2197-6767","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,18]]},"assertion":[{"value":"18 November 2020","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}