{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:27:27Z","timestamp":1774398447688,"version":"3.50.1"},"publisher-location":"Cham","reference-count":47,"publisher":"Springer International Publishing","isbn-type":[{"value":"9783030631062","type":"print"},{"value":"9783030631079","type":"electronic"}],"license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021]]},"DOI":"10.1007\/978-3-030-63107-9_6","type":"book-chapter","created":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T01:01:46Z","timestamp":1613696506000},"page":"65-81","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Multi Sensorial Stimulation Lab: A New Approach for Severe Dementia"],"prefix":"10.1007","author":[{"given":"Alberto","family":"Boccadamo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"De Luca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Palam\u00e0","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Sancarlo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Leone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Diraco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Siciliano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Toma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Maffia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lidia","family":"De Riccardis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo","family":"D\u2019Alessandro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianfranco","family":"Borrelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"Pistoia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,2,17]]},"reference":[{"key":"6_CR1","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/S0197-4580(00)00124-X","volume":"21","author":"H Akiyama","year":"2000","unstructured":"Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM et al (2000) Inflammation and Alzheimer\u2019s disease. Neurobiol Aging 21:383\u2013421","journal-title":"Neurobiol Aging"},{"issue":"1","key":"6_CR2","first-page":"27","volume":"35","author":"E Almirall","year":"2010","unstructured":"Almirall E, Casadesus-Masanell R (2010) Open versus closed innovation: a model of discovery and divergence. Acad Manag Rev 35(1):27\u201347","journal-title":"Acad Manag Rev"},{"issue":"3","key":"6_CR3","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1037\/1089-2680.10.3.229","volume":"10","author":"BM Appelhans","year":"2006","unstructured":"Appelhans BM, Luecken LJ (2006) Heart rate variability as an index of regulated emotional responding. Rev Gen Psychol 10(3):229\u2013240","journal-title":"Rev Gen Psychol"},{"issue":"2","key":"6_CR4","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/j.emj.2017.01.005","volume":"35","author":"L Ardito","year":"2017","unstructured":"Ardito L, Messeni Petruzzelli A (2017) Breadth of external knowledge sourcing and product innovation: the moderating role of strategic human resource practices. Eur Manag J 35(2):261\u2013272","journal-title":"Eur Manag J"},{"key":"6_CR5","unstructured":"American Psychiatric Association (1952) Manuale diagnostico e statistico dei disturbi mentali quinta edizione DSM V. Raffaello Cortina Editore, pp 687\u2013746"},{"issue":"2","key":"6_CR6","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1017\/S0954579401002012","volume":"13","author":"T Beauchaine","year":"2001","unstructured":"Beauchaine T (2001) Vagal tone, development, and Gray\u2019s motivational theory: toward an integrated model of autonomic nervous system functioning in psychopathology. Dev Psychopathol 13(2):183\u2013214","journal-title":"Dev Psychopathol"},{"issue":"4","key":"6_CR7","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1037\/0033-295X.98.4.459","volume":"98","author":"GG Berntson","year":"1991","unstructured":"Berntson GG, Cacioppo JT, Quigley KS (1991) Autonomic determinism: the modes of autonomic control, the doctrine of autonomic space, and the laws of autonomic constraint. Psychol Rev 98(4):459","journal-title":"Psychol Rev"},{"issue":"2","key":"6_CR8","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1111\/j.1469-8986.1993.tb01731.x","volume":"30","author":"GG Berntson","year":"1993","unstructured":"Berntson GG, Cacioppo JT, Quigley KS (1993) Respiratory sinus arrhythmia: autonomic origins, physiological mechanisms, and psychophysiological implications. Psychophysiology 30(2):183\u2013196","journal-title":"Psychophysiology"},{"key":"6_CR9","volume-title":"Opening up healthcare innovation: innovation solutions for a 21st century healthcare system","author":"J Bessant","year":"2012","unstructured":"Bessant J, K\u00fcnne C, M\u00f6slein K (2012) Opening up healthcare innovation: innovation solutions for a 21st century healthcare system. AIM Research, United Kingdom"},{"issue":"1","key":"6_CR10","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.technovation.2010.03.002","volume":"31","author":"M Bianchi","year":"2011","unstructured":"Bianchi M, Cavaliere A, Chiaroni D, Frattini F, Chiesa V (2011) Organisational modes for open innovation in the bio-pharmaceutical industry: an exploratory analysis. Technovation 31(1):22\u201333","journal-title":"Technovation"},{"key":"6_CR11","volume-title":"Handbook of psychophysiology","author":"JT Cacioppo","year":"2007","unstructured":"Cacioppo JT, Tassinary LG, Berntson GG (2007) Handbook of psychophysiology. Cambridge University Press, New York, NY"},{"key":"6_CR12","doi-asserted-by":"crossref","unstructured":"Casacci P, Pistoia M, Leone A, Caroppo A, Siciliano P (2015) Alzheimer patient\u2019s home rehabilitation through ICT advanced technologies: the ALTRUISM project. In: And\u00f2 B, Siciliano P, Marletta V, Monteri\u00f9 A (eds) Ambient assisted living. Bio-systems and biorobotics, vol 11. Springer, Cham","DOI":"10.1007\/978-3-319-18374-9_35"},{"issue":"10","key":"6_CR13","doi-asserted-by":"publisher","first-page":"1895","DOI":"10.1109\/TBME.2007.894731","volume":"54","author":"S Chang","year":"2007","unstructured":"Chang S, Li SJ, Chiang MJ, Hu SJ, Hsyu MC (2007) Fractal dimension estimation via spectral distribution function and its application to physiological signals. IEEE Trans Biomed Eng 54(10):1895\u20131898","journal-title":"IEEE Trans Biomed Eng"},{"key":"6_CR14","doi-asserted-by":"crossref","unstructured":"Chung JC, Lai CK (2002) Snoezelen for dementia. Cochrane Database System Rev (4)","DOI":"10.1002\/14651858.CD003152"},{"issue":"3","key":"6_CR15","first-page":"33","volume":"45","author":"H Chesbrough","year":"2003","unstructured":"Chesbrough H (2003) The logic of open innovation: managing intellectual property. California Manag Rev 45(3):33\u201358","journal-title":"California Manag Rev"},{"key":"6_CR16","unstructured":"Chesbrough H, Bogers M (2014) Explicating open innovation: clarifying an emerging paradigm for understanding innovation. In: Chesbrough H, Vanhaverbeke W, West J (eds) New frontiers in open innovation. Oxford University Press, Oxford, pp 3\u201328"},{"issue":"3","key":"6_CR17","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1111\/j.1467-9310.2006.00428.x","volume":"36","author":"H Chesbrough","year":"2006","unstructured":"Chesbrough H, Crowther AK (2006) Beyond high tech: early adopters of open innovation in other industries. R&D Manag 36(3):229\u2013236","journal-title":"R&D Manag"},{"key":"6_CR18","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1742-2094-9-179","volume":"9","author":"DH Cribbs","year":"2012","unstructured":"Cribbs DH, Berchtold NC, Perreau V, Coleman PD, Rogers J, Tenner AJ et al (2012) Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study. J Neuroinflamm 9:1\u201318","journal-title":"J Neuroinflamm"},{"issue":"6","key":"6_CR19","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1016\/j.respol.2010.01.013","volume":"39","author":"L Dahlander","year":"2010","unstructured":"Dahlander L, Gann DM (2010) How open is innovation? Res Policy 39(6):699\u2013709","journal-title":"Res Policy"},{"key":"6_CR20","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1089\/tmj.2013.0166","volume":"20","author":"MM Davis","year":"2014","unstructured":"Davis MM, Freeman M, Kaye J, Vuckovic N, Buckley DI (2014) A systematic review of clinician and staff views on the acceptability of incorporating remote monitoring tech-nology into primary care. Telemed E-Health 20:428\u2013438","journal-title":"Telemed E-Health"},{"key":"6_CR21","doi-asserted-by":"crossref","unstructured":"Dawson ME, Schell AM, Filion DL (2007) The electrodermal system. In: Handbook of psychophysiology, vol 2, pp 200\u2013223","DOI":"10.1017\/CBO9780511546396.007"},{"issue":"3\/4","key":"6_CR22","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1504\/IJTM.2010.035980","volume":"52","author":"E Enkel","year":"2010","unstructured":"Enkel E (2010) Attributes required for profiting from open innovation in networks. Int J Technol Manag 52(3\/4):344\u2013371","journal-title":"Int J Technol Manag"},{"key":"6_CR23","doi-asserted-by":"crossref","unstructured":"Farooq K, Khan BS, Niazi MA, Leslie SJ, Hussain A (2017) Clinical decision support systems: a visual survey","DOI":"10.31449\/inf.v42i4.1571"},{"key":"6_CR24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.cmpb.2018.04.005","volume":"161","author":"O Faust","year":"2018","unstructured":"Faust O, Hagiwara Y, Hong TJ, Lih OS, Acharya UR (2018) Deep learning for healthcare applications based on physiological signals: a review. Comput Methods Programs Biomed 161:1\u201313","journal-title":"Comput Methods Programs Biomed"},{"key":"6_CR25","doi-asserted-by":"crossref","unstructured":"Goldstein S, Naglieri JA, Princiotta D, Otero TM (2014) Introduction: a history of executive functioning as a theoretical and clinical construct. In: Handbook of executive functioning. Springer, New York, NY, pp 3\u201312","DOI":"10.1007\/978-1-4614-8106-5_1"},{"issue":"2","key":"6_CR26","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.biopsycho.2005.11.014","volume":"74","author":"P Grossman","year":"2007","unstructured":"Grossman P, Taylor EW (2007) Toward understanding respiratory sinus arrhythmia: relations to cardiac vagal tone, evolution and biobehavioral functions. Biol Psychol 74(2):263\u2013285","journal-title":"Biol Psychol"},{"issue":"1","key":"6_CR27","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.technovation.2010.10.002","volume":"31","author":"EK Huizingh","year":"2011","unstructured":"Huizingh EK (2011) Open innovation: state of the art and future perspectives. Technovation 31(1):2\u20139","journal-title":"Technovation"},{"key":"6_CR28","doi-asserted-by":"publisher","first-page":"326","DOI":"10.2174\/1570159X14666151208112754","volume":"14","author":"JYY Szeto","year":"2016","unstructured":"Szeto JYY, Lewis SJG (2016) Current treatment options for Alzheimer\u2019s disease and Parkinson\u2019s disease dementia. Curr Neuropharmacol 14:326\u2013338","journal-title":"Curr Neuropharmacol"},{"key":"6_CR29","unstructured":"Kim JW, Stewart R, Kang HJ, Bae KY, Kim SW, Shin IS, Yoon JS, Kim JM (2018) Longitudinal associations between serum cytokine levels and dementia. Front Psychiatry. Nov 19; 9:606"},{"issue":"1","key":"6_CR30","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/s13132-011-0049-4","volume":"3","author":"L Leydesdorff","year":"2012","unstructured":"Leydesdorff L (2012) The triple helix, quadruple helix, \u2026, and an N-tuple of helices: explanatory models for analyzing the knowledge-based economy? J Knowl Econ 3(1):25\u201335","journal-title":"J Knowl Econ"},{"issue":"2\u20133","key":"6_CR31","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1504\/IJTM.2004.003955","volume":"27","author":"E Lichtenthaler","year":"2004","unstructured":"Lichtenthaler E (2004) Organising the external technology exploitation process: current practices and future challenges. Int J Technol Manag 27(2\u20133):255\u2013271","journal-title":"Int J Technol Manag"},{"issue":"2\u20133","key":"6_CR32","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1016\/j.ejphar.2007.11.071","volume":"583","author":"BS McEwen","year":"2008","unstructured":"McEwen BS (2008) Central effects of stress hormones in health and disease: understanding the protective and damaging effects of stress and stress mediators. Eur J Pharmacol 583(2\u20133):174\u2013185","journal-title":"Eur J Pharmacol"},{"key":"6_CR33","unstructured":"Mulgan G, Tucker S, Ali R, Sanders B (2007) Social innovation: what it is, why it matters and how it can be accelerated. https:\/\/eureka.sbs.ox.ac.uk\/761\/1\/Social_Innovation.pdf. Accessed on 23 March 2017"},{"key":"6_CR34","unstructured":"Musen MA, van Bemmel JH (1997) Handbook of medical informatics. Bohn Stafleu Van Loghum, Houten, the Netherlands"},{"key":"6_CR35","unstructured":"OECD (2018) Care needed: improving the lives of people with dementia. In: OECD health policy studies. OECD Publishing, Paris"},{"key":"6_CR36","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1038\/nri2015","volume":"7","author":"VH Perry","year":"2007","unstructured":"Perry VH, Cunningham C, Holmes C (2007) Systemic infections and inflammation affect chronic neurodegeneration. Nat Rev Immun 7:161\u2013167","journal-title":"Nat Rev Immun"},{"issue":"7315","key":"6_CR37","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1136\/bmj.323.7315.746","volume":"323","author":"PE Plsek","year":"2001","unstructured":"Plsek PE, Wilson T (2001) Complexity, leadership, and management in healthcare organisations. BMJ 323(7315):746\u2013749","journal-title":"BMJ"},{"key":"6_CR38","doi-asserted-by":"crossref","unstructured":"Raimondi G, Casacci P, Sancesario G, Scordamaglia B, Melchiorri G, Pistoia M (2017) Telemedicine for dementia-affected patients: the AAL-ACCESS project experience. In: Cavallo F, Marletta V, Monteri\u00f9 A, Siciliano P (eds) Ambient assisted living. ForItAAL 2016. Lecture notes in electrical engineering, vol 426. Springer, Cham","DOI":"10.1007\/978-3-319-54283-6_28"},{"key":"6_CR39","doi-asserted-by":"crossref","unstructured":"Satti R, Noor-Ul-Hoda Abid MB, De Rui M, Garrido M, Rauofy MR, Montagnese S, Mani AR (2019) The application of the extended Poincar\u00e9 plot in the analysis of physiological variabilities. In: Frontiers in physiology, vol 10","DOI":"10.3389\/fphys.2019.00116"},{"issue":"1","key":"6_CR40","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1108\/BPMJ-06-2017-0173","volume":"25","author":"G Secundo","year":"2019","unstructured":"Secundo G, Toma A, Schiuma G, Passiante G (2019) Knowledge transfer in open innovation: A classification framework for healthcare ecosystems. Bus Process Manag J 25(1):144\u2013163","journal-title":"Bus Process Manag J"},{"key":"6_CR41","doi-asserted-by":"crossref","unstructured":"Society for Psychophysiological Research Ad Hoc Committee on Electrodermal Measures, Boucsein W, Fowles DC, Grimnes S, Ben\u2010Shakhar G, Roth WT, Filion DL et al (2012) Publication recommendations for electrodermal measurements. Psychophysiology 49(8):1017\u20131034","DOI":"10.1111\/j.1469-8986.2012.01384.x"},{"issue":"1","key":"6_CR42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1440-1819.2011.02304.x","volume":"66","author":"M Takeda","year":"2012","unstructured":"Takeda M, Tanaka T, Okochi M, Kazui H (2012) Non-pharmacological intervention for dementia patients. Psychiatry Clin Neurosci 66(1):1\u20137","journal-title":"Psychiatry Clin Neurosci"},{"key":"6_CR43","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1046\/j.1365-2249.1997.4621483.x","volume":"110","author":"E Tarkowski","year":"1997","unstructured":"Tarkowski E, Rosengren L, Blomstrand C, Wikkelso C, Jensen C, Ekholm S et al (1997) Intrathecal release of proand anti-inflammatory cytokines during stroke. Clin Exp Immunol 110:492\u2013499","journal-title":"Clin Exp Immunol"},{"key":"6_CR44","unstructured":"Verheul A (2005) Fundamental philosophy of Snoezelen\u2013historical backround, planning and concept. In: Mertens K, Verheul A (eds) Teoksessa Snoezelen\u2013application fields in practise. ISNA, Germany and the Netherlands, pp 25\u201354"},{"issue":"7","key":"6_CR45","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1287\/mnsc.32.7.791","volume":"32","author":"E Von Hippel","year":"1986","unstructured":"Von Hippel E (1986) Lead users: a source of novel product concepts. Manage Sci 32(7):791\u2013805","journal-title":"Manage Sci"},{"issue":"3","key":"6_CR46","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1007\/s10961-012-9293-4","volume":"39","author":"ML Walshok","year":"2014","unstructured":"Walshok ML, Shapiro JD, Owens N (2014) Transnational innovation networks aren\u2019t all created equal: towards a classification system. J Technol Trans 39(3):345\u2013357","journal-title":"J Technol Trans"},{"issue":"1","key":"6_CR47","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1525\/cmr.2012.55.1.24","volume":"55","author":"PJ Williamson","year":"2012","unstructured":"Williamson PJ, De Meyer A (2012) Ecosystem advantage. California Manag Rev 55(1):24\u201346","journal-title":"California Manag Rev"}],"container-title":["Lecture Notes in Electrical Engineering","Ambient Assisted Living"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-030-63107-9_6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,19]],"date-time":"2021-02-19T09:58:47Z","timestamp":1613728727000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-030-63107-9_6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"ISBN":["9783030631062","9783030631079"],"references-count":47,"URL":"https:\/\/doi.org\/10.1007\/978-3-030-63107-9_6","relation":{},"ISSN":["1876-1100","1876-1119"],"issn-type":[{"value":"1876-1100","type":"print"},{"value":"1876-1119","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"17 February 2021","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}},{"value":"ForItAAL","order":1,"name":"conference_acronym","label":"Conference Acronym","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Italian Forum of Ambient Assisted Living","order":2,"name":"conference_name","label":"Conference Name","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Ancona","order":3,"name":"conference_city","label":"Conference City","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Italy","order":4,"name":"conference_country","label":"Conference Country","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"2019","order":5,"name":"conference_year","label":"Conference Year","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"19 June 2019","order":7,"name":"conference_start_date","label":"Conference Start Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"21 June 2019","order":8,"name":"conference_end_date","label":"Conference End Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"10","order":9,"name":"conference_number","label":"Conference Number","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"foritaal2019","order":10,"name":"conference_id","label":"Conference ID","group":{"name":"ConferenceInfo","label":"Conference Information"}}]}}