{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T17:32:45Z","timestamp":1762018365654,"version":"3.40.3"},"publisher-location":"Cham","reference-count":24,"publisher":"Springer International Publishing","isbn-type":[{"type":"print","value":"9783030634520"},{"type":"electronic","value":"9783030634537"}],"license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T00:00:00Z","timestamp":1620691200000},"content-version":"vor","delay-in-days":130,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Unruptured brain AVMs (bAVMs) remain a controversial subject for practicing neurosurgeons, especially in the light of ARUBA and other observational studies. This retrospective study aims to analyze our experience with unruptured bAVMs to see whether it is beneficial in the long-term and how it corresponds to large literature trials. The study comprised 160 adult patients with unruptured bAVMs surgically treated in Burdenko NMC (Moscow) in 2009\u20132017. Mean age: 33.4\u00a0\u00b1\u00a010\u043b\u0435\u0442. Clinical presentations were: seizures in 99 (61.9%), chronical headaches\u201449 (30.6%), ischemic symptoms\u20144 (2.5%), asymptomatic in 8 (5%) patients. Spetzler-Martin scale: I\u201418\u00a0pt. (11.3%), II\u201471\u00a0pt. (44.4%), III\u201460\u00a0pt. (37.5%), IV\u201411\u00a0pt. (6.8%). Good outcomes (mRS\u00a0=\u00a00\u20132) at discharge were achieved in 149 (93.1%), satisfactory (mRS\u20143)\u20149 (5.6%). Follow-up was complete for 97 (60.6%) patients, mean\u201459.3 (13\u2013108\u00a0month). Excellent outcomes (mRS\u00a0=\u00a00\u20131) reached in 94.8%. For epilepsy patients, Engel I outcome was found in 50 (84.8%); for chronic headaches, 43 (66.1%) patients reported improvement. Postoperative visual field defects were followed in 22 of 55 (40%), complete recovery was reported in 6 (27%) and partial recovery in 8 (36%) patients. Overall, our results support the conclusion that surgery for low-grade bAVMs (S-M I\u2013II) is a beneficial, low-risk option.<\/jats:p>","DOI":"10.1007\/978-3-030-63453-7_13","type":"book-chapter","created":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T18:11:31Z","timestamp":1622657491000},"page":"87-90","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Surgical Treatment of Unruptured Brain AVMs: Short- and Long-Term Results"],"prefix":"10.1007","author":[{"given":"Shalva","family":"Eliava","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vadim","family":"Gorozhanin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oleg","family":"Shekhtman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuri","family":"Pilipenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"Kuchina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,5,11]]},"reference":[{"key":"13_CR1","doi-asserted-by":"publisher","first-page":"598","DOI":"10.1016\/j.wneu.2015.10.060","volume":"87","author":"X Tong","year":"2016","unstructured":"Tong X, Wu J, Lin F, Cao Y, Zhao Y, Ning B, Zhao B, Wang L, Zhang S, Wang S, Zhao J (2016) The effect of age, sex, and lesion location on initial presentation in patients with brain arteriovenous malformations. World Neurosurg 87:598\u2013606","journal-title":"World Neurosurg"},{"key":"13_CR2","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1097\/00006123-200208000-00004","volume":"51","author":"BL Hoh","year":"2002","unstructured":"Hoh BL, Chapman PH, Loeffler JS, Carter BS, Ogilvy CS (2002) Results of multimodality treatment for 141 patients with brain arteriovenous malformations and seizures: factors associated with seizure incidence and seizure outcomes. Neurosurgery 51:303\u2013309","journal-title":"Neurosurgery"},{"key":"13_CR3","doi-asserted-by":"publisher","first-page":"859","DOI":"10.3171\/jns.1990.73.6.0859","volume":"73","author":"RD Brown Jr","year":"1990","unstructured":"Brown RD Jr, Wiebers DO, Forbes GS (1990) Unruptured intracranial aneurysms and arteriovenous malformations: frequency of intracranial hemorrhage and relationship of lesions. J Neurosurg 73:859\u2013863","journal-title":"J Neurosurg"},{"issue":"5","key":"13_CR4","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1227\/01.NEU.0000330401.82582.5E","volume":"63","author":"JA Hernesniemi","year":"2008","unstructured":"Hernesniemi JA, Dashti R, Juvela S, V\u00e4\u00e4rt K, Niemel\u00e4 M, Laakso A (2008) Natural history of brain arteriovenous malformations: a long-term follow-up study of risk of hemorrhage in 238 patients. Neurosurgery 63(5):823\u2013829. discussion 829\u201331","journal-title":"Neurosurgery"},{"issue":"3","key":"13_CR5","doi-asserted-by":"publisher","first-page":"387","DOI":"10.3171\/jns.1990.73.3.0387","volume":"73","author":"SL Ondra","year":"1990","unstructured":"Ondra SL, Troupp H, George ED, Schwab K (1990) The natural history of symptomatic arteriovenous malformations of the brain: a 24-year follow-up assessment. J Neurosurg 73(3):387\u2013391","journal-title":"J Neurosurg"},{"issue":"1","key":"13_CR6","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1161\/STROKEAHA.108.524678","volume":"40","author":"L da Costa","year":"2009","unstructured":"da Costa L, Wallace MC, Ter Brugge KG, O'Kelly C, Willinsky RA, Tymianski M (2009) The natural history and predictive features of hemorrhage from brain arteriovenous malformations. Stroke 40(1):100\u2013105","journal-title":"Stroke"},{"issue":"5","key":"13_CR7","doi-asserted-by":"publisher","first-page":"965","DOI":"10.3171\/JNS-07\/11\/0965","volume":"107","author":"S Yamada","year":"2007","unstructured":"Yamada S, Takagi Y, Nozaki K, Kikuta K, Hashimoto N (2007) Risk factors for subsequent hemorrhage in patients with cerebral arteriovenous malformations. J Neurosurg 107(5):965\u2013972","journal-title":"J Neurosurg"},{"key":"13_CR8","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1016\/j.jocn.2012.01.004","volume":"19","author":"BA Gross","year":"2012","unstructured":"Gross BA, Du R (2012) Surgical and radiosurgical results of the treatment of cerebral arteriovenous malformations. J Clin Neurosci 19:1001\u20131004","journal-title":"J Clin Neurosci"},{"key":"13_CR9","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1016\/j.jocn.2011.12.005","volume":"19","author":"BA Gross","year":"2012","unstructured":"Gross BA, Du R (2012) Rate of rebleeding of arteriovenous malformations in the first year after rupture. J Clin Neurosci 19:1087\u20131088","journal-title":"J Clin Neurosci"},{"key":"13_CR10","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1227\/00006123-199004000-00003","volume":"26","author":"RC Heros","year":"1990","unstructured":"Heros RC, Korosue K, Diebold PM (1990) Surgical excision of cerebral arteriovenous malformations: late results. Neurosurgery 26:570\u2013578","journal-title":"Neurosurgery"},{"key":"13_CR11","doi-asserted-by":"publisher","first-page":"641e646","DOI":"10.3171\/jns.1998.88.4.0641","volume":"88","author":"HJ Pikus","year":"1998","unstructured":"Pikus HJ, Beach ML, Harbaugh RE (1998) Microsurgical treatment of arteriovenous malformations: analysis and comparison with stereotactic radiosurgery. J Neurosurg 88:641e646","journal-title":"J Neurosurg"},{"key":"13_CR12","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1227\/00006123-199012000-00001","volume":"27","author":"MS Dias","year":"1990","unstructured":"Dias MS, Sekhar LN (1990) Intracranial haemorrhage from aneurysms and arteriovenous malformations during pregnancy and the puerperium. Neurosurgery 27:444\u2013446","journal-title":"Neurosurgery"},{"key":"13_CR13","doi-asserted-by":"publisher","first-page":"565","DOI":"10.2176\/nmc.53.565","volume":"53","author":"K Fukuda","year":"2013","unstructured":"Fukuda K, Hamano E, Nakajima N, Katsuragi S, Ikeda T, Takahashi J (2013) Pregnancy and delivery management in patients with cerebral arteriovenous malformation: a single-center experience. Neurol Med Chir (Tokyo) 53:565\u2013570","journal-title":"Neurol Med Chir (Tokyo)"},{"issue":"6","key":"13_CR14","doi-asserted-by":"publisher","first-page":"1507","DOI":"10.1161\/STROKEAHA.117.016828","volume":"48","author":"JL Porras","year":"2017","unstructured":"Porras JL, Yang W, Philadelphia E, Law J, Garzon-Muvdi T, Caplan JM, Colby GP, Coon AL, Tamargo RJ, Huang J (2017) Hemorrhage risk of brain arteriovenous malformations during pregnancy and puerperium in a north American cohort. Stroke 48(6):1507\u20131513","journal-title":"Stroke"},{"key":"13_CR15","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.1007\/s00701-012-1339-8","volume":"154","author":"SJ Hyun","year":"2012","unstructured":"Hyun SJ, Kong DS, Lee JI, Kim JS, Hong SC (2012) Cerebral arteriovenous malformations and seizures: differential impact on the time to seizure-free state according to the treatment modalities. Acta Neurochir 154:1003\u20131010","journal-title":"Acta Neurochir"},{"issue":"6","key":"13_CR16","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1212\/WNL.0b013e3182635696","volume":"79","author":"CB Josephson","year":"2012","unstructured":"Josephson CB, Bhattacharya JJ, Counsell CE, Papanastassiou V, Ritchie V, Roberts R, Sellar R, Warlow CP, Al-Shahi Salman R, Scottish Audit of Intracranial Vascular Malformations (SAIVMs) Steering Committee and Collaborators (2012) Seizure risk with AVM treatment or conservative management: prospective, population based study. Neurology 79(6):500\u2013507","journal-title":"Neurology"},{"key":"13_CR17","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1227\/NEU.0000000000000071","volume":"73","author":"JY Wang","year":"2013","unstructured":"Wang JY, Yang W, Ye X, Rigamonti D, Coon AL, Tamargo RJ, Huang J (2013) Impact on seizure control of surgical resection or radiosurgery for cerebral arteriovenous malformations. Neurosurgery 73:648\u2013655","journal-title":"Neurosurgery"},{"issue":"1","key":"13_CR18","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1007\/s10143-016-0750-7","volume":"40","author":"B Rohn","year":"2017","unstructured":"Rohn B, H\u00e4nggi D, Etminan N, Turowski B, Steiger HJ (2017) Relief of epilepsy and headache and quality of life after microsurgical treatment of unruptured brain AVM-audit of a single-center series and comprehensive review of the literature. Neurosurg Rev 40(1):59\u201365","journal-title":"Neurosurg Rev"},{"key":"13_CR19","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1177\/0333102413485658","volume":"33","author":"Headache Classification Committee of the International Headache Society","year":"2013","unstructured":"Headache Classification Committee of the International Headache Society (2013) The international classification of headache disorders, 3rd edition (beta version). Cephalalgia 33:629\u2013808","journal-title":"Cephalalgia"},{"key":"13_CR20","doi-asserted-by":"publisher","first-page":"2794","DOI":"10.1161\/01.STR.0000043674.99741.9B","volume":"33","author":"HT ApSimon","year":"2002","unstructured":"ApSimon HT, Reef H, Phadke RV, Popovic EA (2002) A population-based study of brain arteriovenous malformation: long-term treatment outcomes. Stroke 33:2794\u20132800","journal-title":"Stroke"},{"key":"13_CR21","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1212\/WNL.46.4.949","volume":"46","author":"RD Brown Jr","year":"1996","unstructured":"Brown RD Jr, Wiebers DO, Torner JC, O\u2019Fallon WN (1996) Incidence and prevalence of intracranial vascular malformations in Olmsted County, Minnesota, 1965 to 1992. Neurology 46:949\u2013952","journal-title":"Neurology"},{"key":"13_CR22","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/978-3-319-02411-0_19","volume":"119","author":"HJ Steiger","year":"2014","unstructured":"Steiger HJ, Etminan N, H\u00e4nggi D (2014) Epilepsy and headache after resection of cerebral arteriovenous malformations. Acta Neurochir Suppl 119:113\u2013115","journal-title":"Acta Neurochir Suppl"},{"key":"13_CR23","doi-asserted-by":"publisher","first-page":"742","DOI":"10.3171\/2009.11.JNS09884","volume":"113","author":"AR Dehdashti","year":"2010","unstructured":"Dehdashti AR, Thines L, Willinsky RA, ter Brugge KG, Schwartz ML, Tymianski M, Wallace MC (2010) Multidisciplinary care of occipital arteriovenous malformations: effect on nonhemorrhagic headache, vision, and outcome in a series of 135 patients. Clinical article. J Neurosurg 113:742\u2013748","journal-title":"J Neurosurg"},{"key":"13_CR24","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1227\/00006123-199609000-00005","volume":"39","author":"C Lundqvist","year":"1996","unstructured":"Lundqvist C, Wikholm G, Svendsen P (1996) Embolization of cerebral arteriovenous malformations: part II\u2013aspects of complications and late outcome. Neurosurgery 39:460\u2013467","journal-title":"Neurosurgery"}],"container-title":["Acta Neurochirurgica Supplement","Trends in Cerebrovascular Surgery and Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-030-63453-7_13","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,4]],"date-time":"2023-11-04T12:34:36Z","timestamp":1699101276000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-030-63453-7_13"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"ISBN":["9783030634520","9783030634537"],"references-count":24,"URL":"https:\/\/doi.org\/10.1007\/978-3-030-63453-7_13","relation":{},"ISSN":["0065-1419","2197-8395"],"issn-type":[{"type":"print","value":"0065-1419"},{"type":"electronic","value":"2197-8395"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"11 May 2021","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}