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MBR and JN are co-inventors on US patent application 14\/318,082 (assigned to UAB Research Foundation). ALH and CR declare no conflict of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"Not applicable, as this is a review article and, thus, there are no human subjects recruited for this study or any animals used.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Not applicable, as this is a review article and, thus, there are no human subjects recruited for this study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}}]}}