{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:15:18Z","timestamp":1787318118408,"version":"build-2736575974"},"publisher-location":"Cham","reference-count":25,"publisher":"Springer Nature Switzerland","isbn-type":[{"value":"9783031441455","type":"print"},{"value":"9783031441462","type":"electronic"}],"license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023]]},"DOI":"10.1007\/978-3-031-44146-2_18","type":"book-chapter","created":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T05:02:22Z","timestamp":1695358942000},"page":"181-190","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Secure Genotype Imputation Using the\u00a0Hidden Markov Model with\u00a0Homomorphic Encryption"],"prefix":"10.1007","author":[{"given":"Chloe S.","family":"de Leon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard Bryann","family":"Chua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,9,23]]},"reference":[{"issue":"3","key":"18_CR1","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1093\/bib\/bbx139","volume":"20","author":"MMA Aziz","year":"2017","unstructured":"Aziz, M.M.A., et al.: Privacy-preserving techniques of genomic data - a survey. Brief. Bioinform. 20(3), 887\u2013895 (2017)","journal-title":"Brief. Bioinform."},{"key":"18_CR2","doi-asserted-by":"crossref","unstructured":"Blatt, M., Gusev, A., Polyakov, Y., Rohloff, K., Vaikuntanathan, V.: Optimized homomorphic encryption solution for secure genome-wide association studies (2019)","DOI":"10.1186\/s12920-020-0719-9"},{"key":"18_CR3","doi-asserted-by":"crossref","unstructured":"Carpov, S., Gama, N., Georgieva, M., Troncoso-Pastoriza, J.R.: Privacy-preserving semi-parallel logistic regression training with fully homomorphic encryption. BMC Med. Genomics 13(S7) (2020)","DOI":"10.1186\/s12920-020-0723-0"},{"key":"18_CR4","doi-asserted-by":"crossref","unstructured":"Chakraborty, O., Zuber, M.: Efficient and accurate homomorphic comparisons. In: WAHC\u201922, pp. 35-46. Association for Computing Machinery, New York, NY (2022)","DOI":"10.1145\/3560827.3563375"},{"key":"18_CR5","series-title":"Lecture Notes in Computer Science","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1007\/978-3-319-70694-8_15","volume-title":"Advances in Cryptology \u2013 ASIACRYPT 2017","author":"JH Cheon","year":"2017","unstructured":"Cheon, J.H., Kim, A., Kim, M., Song, Y.: Homomorphic encryption for arithmetic of approximate numbers. In: Takagi, T., Peyrin, T. (eds.) ASIACRYPT 2017. LNCS, vol. 10624, pp. 409\u2013437. Springer, Cham (2017). https:\/\/doi.org\/10.1007\/978-3-319-70694-8_15"},{"key":"18_CR6","series-title":"Lecture Notes in Computer Science","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1007\/978-3-030-34621-8_15","volume-title":"Advances in Cryptology \u2013 ASIACRYPT 2019","author":"JH Cheon","year":"2019","unstructured":"Cheon, J.H., Kim, D., Kim, D., Lee, H.H., Lee, K.: Numerical method for comparison on homomorphically encrypted numbers. In: Galbraith, S.D., Moriai, S. (eds.) ASIACRYPT 2019. LNCS, vol. 11922, pp. 415\u2013445. Springer, Cham (2019). https:\/\/doi.org\/10.1007\/978-3-030-34621-8_15"},{"key":"18_CR7","unstructured":"Chialva, D., Dooms, A.: Conditionals in homomorphic encryption and machine learning applications. CoRR abs\/1810.12380. arXiv:1810.12380 (2018)"},{"key":"18_CR8","doi-asserted-by":"crossref","unstructured":"Dathathri, R., Kostova, B., Saarikivi, O., Dai, W., Laine, K., Musuvathi, M.: EVA: an encrypted vector arithmetic language and compiler for efficient homomorphic computation. In: Proceedings of the 41st ACM SIGPLAN Conference on Programming Language Design and Implementation. arXiv:1912.11951 (2020)","DOI":"10.1145\/3385412.3386023"},{"key":"18_CR9","doi-asserted-by":"crossref","unstructured":"Franzese, M., Iuliano, A.: Hidden Markov models. Encyclopedia of Bioinformatics and Computational Biology, pp. 753\u2014762 (2019)","DOI":"10.1016\/B978-0-12-809633-8.20488-3"},{"issue":"3","key":"18_CR10","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1145\/1666420.1666444","volume":"53","author":"C Gentry","year":"2010","unstructured":"Gentry, C.: Computing arbitrary functions of encrypted data. Commun. ACM 53(3), 97\u2013105 (2010)","journal-title":"Commun. ACM"},{"key":"18_CR11","unstructured":"Gursoy, G., Harmanci, A., Green, M.E., Navarro, F.C., Gerstein, M.: Sensitive information leakage from functional genomics data: theoretical quantifications and practical file formats for privacy preservation (2018)"},{"issue":"3","key":"18_CR12","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1038\/nmeth.3746","volume":"13","author":"A Harmanci","year":"2016","unstructured":"Harmanci, A., Gerstein, M.: Quantification of private information leakage from phenotype-genotype data: linking attacks. Nat. Methods 13(3), 251\u2013256 (2016)","journal-title":"Nat. Methods"},{"issue":"3","key":"18_CR13","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1093\/sysbio\/syu046","volume":"65","author":"H Huang","year":"2014","unstructured":"Huang, H., Knowles, L.L.: Unforeseen consequences of excluding missing data from next-generation sequences: simulation study of RAD sequences. Syst. Biol. 65(3), 357\u2013365 (2014)","journal-title":"Syst. Biol."},{"key":"18_CR14","doi-asserted-by":"crossref","unstructured":"Kim, A., Song, Y., Kim, M., Lee, K., Cheon, J.H.: Logistic regression model training based on the approximate homomorphic encryption. BMC Med. Genomics 11(S4) (2018)","DOI":"10.1186\/s12920-018-0401-7"},{"key":"18_CR15","doi-asserted-by":"crossref","unstructured":"Kim, M., et\u00a0al.: Ultra-fast homomorphic encryption models enable secure outsourcing of genotype imputation (2020)","DOI":"10.1101\/2020.07.02.183459"},{"key":"18_CR16","series-title":"Lecture Notes in Computer Science","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/978-3-319-16295-9_1","volume-title":"Progress in Cryptology - LATINCRYPT 2014","author":"K Lauter","year":"2015","unstructured":"Lauter, K., L\u00f3pez-Alt, A., Naehrig, M.: Private computation on encrypted genomic data. In: Aranha, D.F., Menezes, A. (eds.) LATINCRYPT 2014. LNCS, vol. 8895, pp. 3\u201327. Springer, Cham (2015). https:\/\/doi.org\/10.1007\/978-3-319-16295-9_1"},{"key":"18_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1472-6947-15-S5-S1","volume":"15","author":"WJ Lu","year":"2015","unstructured":"Lu, W.J., Yamada, Y., Sakuma, J.: Privacy-preserving genome-wide association studies on cloud environment using fully homomorphic encryption. BMC Med. Inform. Decis. Mak. 15, 1\u20138 (2015)","journal-title":"BMC Med. Inform. Decis. Mak."},{"issue":"3","key":"18_CR18","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1145\/3546934","volume":"20","author":"S Mondal","year":"2022","unstructured":"Mondal, S., Gharote, M.S., Lodha, S.P.: Privacy of personal information: Going incog in a goldfish bowl. Queue 20(3), 41\u201387 (2022). https:\/\/doi.org\/10.1145\/3546934","journal-title":"Queue"},{"key":"18_CR19","doi-asserted-by":"crossref","unstructured":"Mott, R., Fischer, C., Prins, P., Davies, R.W.: Private genomes and public SNPs: homomorphic encryption of genotypes and phenotypes for shared quantitative genetics (2020)","DOI":"10.1101\/2020.04.02.021865"},{"issue":"1","key":"18_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1145\/2767007","volume":"48","author":"M Naveed","year":"2015","unstructured":"Naveed, M., et al.: Privacy in the genomic era. ACM Comput. Surv. 48(1), 1\u201344 (2015). https:\/\/doi.org\/10.1145\/2767007","journal-title":"ACM Comput. Surv."},{"issue":"3","key":"18_CR21","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1159\/000489758","volume":"83","author":"S Shi","year":"2019","unstructured":"Shi, S., et al.: Comprehensive assessment of genotype imputation performance. Hum. Hered. 83(3), 107\u2013116 (2019)","journal-title":"Hum. Hered."},{"key":"18_CR22","doi-asserted-by":"crossref","unstructured":"Sim, J.J., Chan, F.M., Chen, S., Tan, B.H.M., Aung, K.M.M.: Achieving GWAS with homomorphic encryption, 1\u201324 (2019)","DOI":"10.1186\/s12920-020-0717-y"},{"key":"18_CR23","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1038\/nrg.2017.101","volume":"19","author":"NJ Timpson","year":"2017","unstructured":"Timpson, N.J., Greenwood, C.M.T., Soranzo, N., Lawson, D.J., Richards, J.B.: Genetic architecture: the shape of the genetic contribution to human traits and disease. Nat. Rev. Genet. 19, 110\u2013124 (2017)","journal-title":"Nat. Rev. Genet."},{"key":"18_CR24","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1038\/mp.2016.244","volume":"22","author":"JW Trampush","year":"2017","unstructured":"Trampush, J.W., Yang, M.L.Z., Lencz, T.: GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium. Mol. Psychiatry 22, 336\u2013345 (2017)","journal-title":"Mol. Psychiatry"},{"key":"18_CR25","doi-asserted-by":"crossref","unstructured":"Viand, A., Jattke, P., Hithnawi, A.: SoK: fully homomorphic encryption compilers (2021)","DOI":"10.1109\/SP40001.2021.00068"}],"container-title":["Lecture Notes in Networks and Systems","Novel & Intelligent Digital Systems: Proceedings of the 3rd International Conference (NiDS 2023)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-031-44146-2_18","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T05:14:06Z","timestamp":1695359646000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-031-44146-2_18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"ISBN":["9783031441455","9783031441462"],"references-count":25,"URL":"https:\/\/doi.org\/10.1007\/978-3-031-44146-2_18","relation":{},"ISSN":["2367-3370","2367-3389"],"issn-type":[{"value":"2367-3370","type":"print"},{"value":"2367-3389","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023]]},"assertion":[{"value":"23 September 2023","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}},{"value":"NiDS","order":1,"name":"conference_acronym","label":"Conference Acronym","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Novel & Intelligent Digital Systems Conferences","order":2,"name":"conference_name","label":"Conference Name","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Athens","order":3,"name":"conference_city","label":"Conference City","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Greece","order":4,"name":"conference_country","label":"Conference Country","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"2023","order":5,"name":"conference_year","label":"Conference Year","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"28 September 2023","order":7,"name":"conference_start_date","label":"Conference Start Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"29 September 2023","order":8,"name":"conference_end_date","label":"Conference End Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"nids2023","order":10,"name":"conference_id","label":"Conference ID","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"https:\/\/iis-international.org\/nids2022\/","order":11,"name":"conference_url","label":"Conference URL","group":{"name":"ConferenceInfo","label":"Conference Information"}}]}}