{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:44:53Z","timestamp":1790628293186,"version":"4.1.0"},"publisher-location":"Cham","reference-count":48,"publisher":"Springer Nature Switzerland","isbn-type":[{"value":"9783031571640","type":"print"},{"value":"9783031571657","type":"electronic"}],"license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024]]},"DOI":"10.1007\/978-3-031-57165-7_11","type":"book-chapter","created":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T07:02:03Z","timestamp":1716793323000},"page":"171-181","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Orf, a Human Parapoxvirus Infection"],"prefix":"10.1007","author":[{"given":"Rujittika","family":"Mungmunpuntipantip","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viroj","family":"Wiwanitkit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,28]]},"reference":[{"key":"11_CR1","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.927579","volume":"21","author":"AM Alajlan","year":"2020","unstructured":"Alajlan AM, Alsubeeh NA (2020) Orf (ecthyma contagiosum) transmitted from a camel to a human: a case report. Am J Case Rep 21:e927579","journal-title":"Am J Case Rep"},{"key":"11_CR2","doi-asserted-by":"crossref","unstructured":"\u00c1lvarez-Arg\u00fcelles ME, Mel\u00f3n Garc\u00eda S, Boga JA, Navarro Mde O (2015) Molecular diagnosis of parapoxvirus infection. Med Clin (Barc) 145(9):e17\u2013e18","DOI":"10.1016\/j.medcle.2016.03.011"},{"key":"11_CR3","doi-asserted-by":"crossref","unstructured":"Andreani J, Fongue J, Bou Khalil JY, David L, Mougari S, Le Bideau M, Abrah\u00e3o J, Berbis P, La Scola B (2019) Human infection with orf virus and description of its whole genome, France, 2017. Emerg Infect Dis 25(12):2197\u20132204","DOI":"10.3201\/eid2512.181513"},{"issue":"1","key":"11_CR4","doi-asserted-by":"publisher","first-page":"43","DOI":"10.2478\/jvetres-2022-0005","volume":"66","author":"Y Badr","year":"2022","unstructured":"Badr Y, Rahman MM, Ohno Y, Ishijima K, Maeda K, Kohyama K, Kamatari YO, Shimizu K, Okada A, Inoshima Y (2022) A new enzyme-linked immunosorbent assay for serological diagnosis of seal parapoxvirus infection in marine mammals. J Vet Res 66(1):43\u201352","journal-title":"J Vet Res"},{"key":"11_CR6","doi-asserted-by":"publisher","unstructured":"Bergqvist C, Kurban M, Abbas O (2017) Orf virus infection. Rev Med Virol27(4). https:\/\/doi.org\/10.1002\/rmv.1932","DOI":"10.1002\/rmv.1932"},{"issue":"5","key":"11_CR5","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.annder.2019.03.001","volume":"146","author":"G Bohelay","year":"2019","unstructured":"Bohelay G, Duong TA (2019) Human poxvirus infections. Ann Dermatol Venereol 146(5):387\u2013398","journal-title":"Ann Dermatol Venereol"},{"issue":"1\u20132","key":"11_CR7","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1007\/s13337-015-0255-y","volume":"26","author":"M Bora","year":"2015","unstructured":"Bora M, Bora DP, Barman NN, Borah B, Bora PL, Talukdar A, Tamuly S (2015) Isolation and molecular characterization of orf virus from natural outbreaks in goats of Assam. Virusdisease 26(1\u20132):82\u201388","journal-title":"Virusdisease"},{"key":"11_CR8","doi-asserted-by":"crossref","unstructured":"Bukar AM, Jesse FFA, Abdullah CAC, Noordin MM, Lawan Z, Mangga HK, Balakrishnan KN, Azmi MM (2021) Immunomodulatory strategies for parapoxvirus: current status and future approaches for the development of vaccines against orf virus infection. Vaccines (Basel) 9(11):1341","DOI":"10.3390\/vaccines9111341"},{"issue":"1","key":"11_CR9","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1128\/mr.55.1.80-122.1991","volume":"55","author":"RM Buller","year":"1991","unstructured":"Buller RM, Palumbo GJ (1991) Poxvirus pathogenesis. Microbiol Rev 55(1):80\u2013122","journal-title":"Microbiol Rev"},{"issue":"2","key":"11_CR10","first-page":"163","volume":"13","author":"M B\u00fcttner","year":"1985","unstructured":"B\u00fcttner M (1985) Ecthyma of sheep and goats. Tierarztl Prax 13(2):163\u2013169","journal-title":"Tierarztl Prax"},{"issue":"7","key":"11_CR11","first-page":"684","volume":"16","author":"JV Caravaglio","year":"2017","unstructured":"Caravaglio JV, Khachemoune A (2017) Orf virus infection in humans: a review with a focus on advances in diagnosis and treatment. J Drugs Dermatol 16(7):684\u2013689","journal-title":"J Drugs Dermatol"},{"issue":"2","key":"11_CR12","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1002\/vms3.700","volume":"8","author":"V Cicculli","year":"2022","unstructured":"Cicculli V, Ayhan N, Luciani L, Pezzi L, Maitre A, Decarreaux D, de Lamballerie X, Paoli JC, Vial L, Charrel R, Falchi A (2022) Molecular detection of parapoxvirus in Ixodidae ticks collected from cattle in Corsica, France. Vet Med Sci 8(2):907\u2013916","journal-title":"Vet Med Sci"},{"key":"11_CR13","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2021.653094","volume":"8","author":"H Costa","year":"2021","unstructured":"Costa H, Klein J, Breines EM, Nollens HH, Matassa K, Garron M, Duignan PJ, Schmitt T, Goldstein T, Tryland M (2021) A comparison of parapoxviruses in North American Pinnipeds. Front Vet Sci 8:653094","journal-title":"Front Vet Sci"},{"issue":"1","key":"11_CR14","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2174\/1574891X12666170602080301","volume":"12","author":"H Demiraslan","year":"2017","unstructured":"Demiraslan H, Dinc G, Doganay M (2017) An Overview of orf virus infection in humans and animals. Recent Pat Antiinfect Drug Discov 12(1):21\u201330","journal-title":"Recent Pat Antiinfect Drug Discov"},{"issue":"1","key":"11_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1067\/mjd.2001.109302","volume":"44","author":"DG Diven","year":"2001","unstructured":"Diven DG (2001) An overview of poxviruses. J Am Acad Dermatol 44(1):1\u201316","journal-title":"J Am Acad Dermatol"},{"issue":"12","key":"11_CR16","first-page":"691","volume":"65","author":"H Engel","year":"2010","unstructured":"Engel H, Marot L, Zech F, Thys F (2010) The \u201corf\u201d virus: focus and review of the literature. Rev Med Liege 65(12):691\u2013695","journal-title":"Rev Med Liege"},{"issue":"3\u20134","key":"11_CR17","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/j.vetmic.2009.08.026","volume":"140","author":"S Essbauer","year":"2010","unstructured":"Essbauer S, Pfeffer M, Meyer H (2010) Zoonotic poxviruses. Vet Microbiol 140(3\u20134):229\u2013236","journal-title":"Vet Microbiol"},{"issue":"3","key":"11_CR18","doi-asserted-by":"publisher","first-page":"1505","DOI":"10.3390\/v7031505","volume":"7","author":"SB Fleming","year":"2015","unstructured":"Fleming SB, Wise LM, Mercer AA (2015) Molecular genetic analysis of orf virus: a poxvirus that has adapted to skin. Viruses 7(3):1505\u20131539","journal-title":"Viruses"},{"issue":"6","key":"11_CR19","doi-asserted-by":"publisher","first-page":"607","DOI":"10.4067\/S0716-10182017000600607","volume":"34","author":"C Flores","year":"2017","unstructured":"Flores C, Gonz\u00e1lez E, Verna A, Peralta A, Madariaga C, Ode\u00f3n A, Cant\u00f3n G (2017) Orf virus in human, confirmation in case report from Chile. Rev Chilena Infectol 34(6):607\u2013609","journal-title":"Rev Chilena Infectol"},{"issue":"26","key":"11_CR20","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1136\/vr.120.26.624","volume":"120","author":"RA Fox","year":"1987","unstructured":"Fox RA (1987) Orf vaccine supplies. Vet Rec 120(26):624","journal-title":"Vet Rec"},{"issue":"Pt 6","key":"11_CR21","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.1099\/vir.0.000080","volume":"96","author":"S Friederichs","year":"2015","unstructured":"Friederichs S, Krebs S, Blum H, Lang H, B\u00fcttner M (2015) Parapoxvirus (PPV) of red deer reveals subclinical infection and confirms a unique species. J Gen Virol 96(Pt 6):1446\u20131462","journal-title":"J Gen Virol"},{"issue":"1\u20132","key":"11_CR22","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/BF01310961","volume":"83","author":"U Gassmann","year":"1985","unstructured":"Gassmann U, Wyler R, Wittek R (1985) Analysis of parapoxvirus genomes. Arch Virol 83(1\u20132):17\u201331","journal-title":"Arch Virol"},{"issue":"2","key":"11_CR23","doi-asserted-by":"publisher","first-page":"194.e1","DOI":"10.1016\/j.jhsa.2020.12.010","volume":"47","author":"M Gore Karaali","year":"2022","unstructured":"Gore Karaali M, Gurel MS, Sar\u0131 Y, Kara Polat A, Leblebici C (2022) Solitary subungual orf. J Hand Surg Am 47(2):194.e1\u2013194.e3","journal-title":"J Hand Surg Am"},{"issue":"1\u20132","key":"11_CR24","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/S0168-1702(02)00117-X","volume":"88","author":"DM Haig","year":"2002","unstructured":"Haig DM, McInnes CJ (2002) Immunity and counter-immunity during infection with the parapoxvirus orf virus. Virus Res 88(1\u20132):3\u201316","journal-title":"Virus Res"},{"issue":"4","key":"11_CR25","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1080\/00480169.1987.35376","volume":"35","author":"GW Horner","year":"1987","unstructured":"Horner GW, Robinson AJ, Hunter R, Cox BT, Smith R (1987) Parapoxvirus infections in New Zealand farmed red deer (Cervus elaphus). N Z Vet J 35(4):41\u201345","journal-title":"N Z Vet J"},{"issue":"3","key":"11_CR26","first-page":"233","volume":"50","author":"HP Huemer","year":"2014","unstructured":"Huemer HP, Zobl A, Windisch A, Glawischnig W, B\u00fcttner M, Kitchen M, Trevisiol K (2014) Serological evidence for parapoxvirus infection in chamois from the Tyrol regions of Austria and Italy. Vet Ital 50(3):233\u2013236","journal-title":"Vet Ital"},{"issue":"4","key":"11_CR27","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1111\/j.1348-0421.2002.tb02697.x","volume":"46","author":"Y Iketani","year":"2002","unstructured":"Iketani Y, Inoshima Y, Asano A, Murakami K, Shimizu S, Sentsui H (2002) Persistent parapoxvirus infection in cattle. Microbiol Immunol 46(4):285\u2013291","journal-title":"Microbiol Immunol"},{"key":"11_CR28","first-page":"153","volume":"12","author":"T Kassa","year":"2021","unstructured":"Kassa T (2021) A review on human orf: a neglected viral zoonosis. Res Rep Trop Med 12:153\u2013172","journal-title":"Res Rep Trop Med"},{"key":"11_CR29","doi-asserted-by":"crossref","unstructured":"Kuroda Y, Yoshida M, Shibahara T, Matsui T, Nakane T, Hara H, Inoshima Y, Sentsui H (1999) An epidemic of parapoxvirus infection among cattle: isolation and antibody survey. J Vet Med Sci 61(7):749\u2013753","DOI":"10.1292\/jvms.61.749"},{"issue":"3","key":"11_CR30","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1038\/nrmicro1099","volume":"3","author":"G McFadden","year":"2005","unstructured":"McFadden G (2005) Poxvirus tropism. Nat Rev Microbiol 3(3):201\u2013213","journal-title":"Nat Rev Microbiol"},{"issue":"9","key":"11_CR31","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a010199","volume":"5","author":"B Moss","year":"2013","unstructured":"Moss B (2013) Poxvirus DNA replication. Cold Spring Harb Perspect Biol 5(9):a010199","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"11_CR32","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1016\/j.virol.2015.02.003","volume":"479\u2013480","author":"B Moss","year":"2015","unstructured":"Moss B (2015) Poxvirus membrane biogenesis. Virology 479\u2013480:619\u2013626","journal-title":"Virology"},{"issue":"1","key":"11_CR33","doi-asserted-by":"publisher","first-page":"11","DOI":"10.3354\/dao02405","volume":"97","author":"Y Ohno","year":"2011","unstructured":"Ohno Y, Inoshima Y, Maeda K, Ishiguro N (2011) Molecular analysis of parapoxvirus from a spotted seal Phoca largha in Japan. Dis Aquat Organ 97(1):11\u201316","journal-title":"Dis Aquat Organ"},{"issue":"11","key":"11_CR34","doi-asserted-by":"publisher","first-page":"331","DOI":"10.3390\/v9110331","volume":"9","author":"GP Oliveira","year":"2017","unstructured":"Oliveira GP, Rodrigues RAL, Lima MT, Drumond BP, Abrah\u00e3o JS (2017) Poxvirus host range genes and virus-host spectrum: a critical review. Viruses 9(11):331","journal-title":"Viruses"},{"issue":"1","key":"11_CR35","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1111\/ced.12697","volume":"41","author":"V Rajkomar","year":"2016","unstructured":"Rajkomar V, Hannah M, Coulson IH, Owen CM (2016) A case of human to human transmission of orf between mother and child. Clin Exp Dermatol 41(1):60\u201363","journal-title":"Clin Exp Dermatol"},{"key":"11_CR36","unstructured":"Robinson AJ, Lyttle DJ (1992) Parapoxviruses: their biology and potential as recombinant vaccines. In: Recombinant poxviruses. CRC Press, pp 285\u2013327"},{"issue":"3","key":"11_CR37","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/j.antiviral.2006.09.008","volume":"73","author":"A Scagliarini","year":"2007","unstructured":"Scagliarini A, McInnes CJ, Gallina L, Dal Pozzo F, Scagliarini L, Snoeck R, Prosperi S, Sales J, Gilray JA, Nettleton PF (2007) Antiviral activity of HPMPC (cidofovir) against orf virus infected lambs. Antiviral Res 73(3):169\u2013174","journal-title":"Antiviral Res"},{"issue":"4","key":"11_CR38","doi-asserted-by":"publisher","first-page":"684","DOI":"10.3201\/eid1704.101454","volume":"17","author":"A Scagliarini","year":"2011","unstructured":"Scagliarini A, Vaccari F, Turrini F, Bianchi A, Cordioli P, Lavazza A (2011) Parapoxvirus infections of red deer, Italy. Emerg Infect Dis 17(4):684\u2013687","journal-title":"Emerg Infect Dis"},{"key":"11_CR39","doi-asserted-by":"crossref","unstructured":"Smith GW, Scherba G, Constable PD, Hsiao V, Behr MJ, Morin DE (2002) Atypical parapoxvirus infection in sheep. J Vet Intern Med 16(3):287\u2013292","DOI":"10.1111\/j.1939-1676.2002.tb02371.x"},{"issue":"1\u20132","key":"11_CR40","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.vetmic.2015.08.010","volume":"181","author":"V Spyrou","year":"2015","unstructured":"Spyrou V, Valiakos G (2015) Orf virus infection in sheep or goats. Vet Microbiol 181(1\u20132):178\u2013182","journal-title":"Vet Microbiol"},{"key":"11_CR41","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2021.109105","volume":"258","author":"X Tang","year":"2021","unstructured":"Tang X, Jing T, Chen X, Wang T, Xie Y, Chen F, Wen Y, Chang J, Chen D, Ma W (2021) Interleukin-17 mediates inflammatory tissue injury during orf development in goats. Vet Microbiol 258:109105","journal-title":"Vet Microbiol"},{"key":"11_CR42","doi-asserted-by":"crossref","unstructured":"Tryland M, Klein J, Berger T, Josefsen TD, das Neves CG, Oksanen A, \u00c5sbakk K (2013) Experimental parapoxvirus infection (contagious ecthyma) in semi-domesticated reindeer (Rangifer tarandus tarandus). Vet Microbiol 162(2\u20134):499\u2013506","DOI":"10.1016\/j.vetmic.2012.10.039"},{"issue":"1\u20132","key":"11_CR43","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.virusres.2006.09.012","volume":"124","author":"N Ueda","year":"2007","unstructured":"Ueda N, Inder MK, Wise LM, Fleming SB, Mercer AA (2007) Parapoxvirus of red deer in New Zealand encodes a variant of viral vascular endothelial growth factor. Virus Res 124(1\u20132):50\u201358","journal-title":"Virus Res"},{"key":"11_CR44","first-page":"347","volume":"269","author":"C Upton","year":"2014","unstructured":"Upton C (2014) Poxvirus bioinformatics. Methods Mol Biol 269:347\u2013370","journal-title":"Methods Mol Biol"},{"key":"11_CR45","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/S0065-3527(08)00003-1","volume":"71","author":"SJ Werden","year":"2008","unstructured":"Werden SJ, Rahman MM, McFadden G (2008) Poxvirus host range genes. Adv Virus Res 71:135\u2013171","journal-title":"Adv Virus Res"},{"issue":"1","key":"11_CR46","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.2013","volume":"29","author":"R Wang","year":"2019","unstructured":"Wang R, Wang Y, Liu F, Luo S (2019) Orf virus: a promising new therapeutic agent. Rev Med Virol 29(1):e2013","journal-title":"Rev Med Virol"},{"issue":"4","key":"11_CR47","doi-asserted-by":"publisher","first-page":"383","DOI":"10.2460\/ajvr.77.4.383","volume":"77","author":"G Yaegashi","year":"2016","unstructured":"Yaegashi G, Fukunari K, Oyama T, Murakami RK, Inoshima Y (2016) Detection and quantification of parapoxvirus DNA by use of a quantitative real-time polymerase chain reaction assay in calves without clinical signs of parapoxvirus infection. Am J Vet Res 77(4):383\u2013387","journal-title":"Am J Vet Res"},{"key":"11_CR48","doi-asserted-by":"crossref","unstructured":"Zhang K, Liu Y, Kong H, Shang Y, Liu X (2014) Human infection with orf virus from goats in China, 2012. Vector Borne Zoonotic Dis 14(5):365\u2013367","DOI":"10.1089\/vbz.2013.1445"}],"container-title":["Advances in Experimental Medicine and Biology","Poxviruses"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-031-57165-7_11","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,27]],"date-time":"2024-05-27T07:05:24Z","timestamp":1716793524000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-031-57165-7_11"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"ISBN":["9783031571640","9783031571657"],"references-count":48,"URL":"https:\/\/doi.org\/10.1007\/978-3-031-57165-7_11","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]},"assertion":[{"value":"28 May 2024","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}