{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:01:14Z","timestamp":1786978874917,"version":"build-2736575974"},"publisher-location":"Cham","reference-count":238,"publisher":"Springer International Publishing","isbn-type":[{"value":"9783031583100","type":"print"},{"value":"9783031583117","type":"electronic"}],"license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024]]},"DOI":"10.1007\/978-3-031-58311-7_3","type":"book-chapter","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T07:01:21Z","timestamp":1716879681000},"page":"37-64","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The Impact of Centrosome Pathologies on Ovarian Cancer Development and Progression with a Focus on Centrosomes as Therapeutic Target"],"prefix":"10.1007","author":[{"given":"Heide","family":"Schatten","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,5,29]]},"reference":[{"key":"3_CR1","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1021\/mp700113r","volume":"4","author":"P Anand","year":"2007","unstructured":"Anand P, Kunnumakkara AB, Newman RA, Aggarwal BB (2007). Bioavailability of curcumin: problems and promises. Mol Pharm 4:807\u2013818.","journal-title":"Mol Pharm"},{"key":"3_CR2","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1038\/nature02166","volume":"426","author":"JS Andersen","year":"2003","unstructured":"Andersen JS, Wilkinson CJ, Mayor T, Mortensen P, Nigg EA, Mann M (2003). Proteomic characterization of the human centrosome by protein correlation profiling. Nature 426:570\u2013574.","journal-title":"Nature"},{"key":"3_CR3","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.ygyno.2003.12.041","volume":"93","author":"SM Apte","year":"2004","unstructured":"Apte SM, Bucana CD, Killion JJ, Gershenson DM, Fidler IJ (2004). Expression of platelet-derived growth factor and activated receptor in clinical specimens of epithelial ovarian cancer and ovarian carcinoma cell lines. Gynecol Oncol 93:78\u201386.","journal-title":"Gynecol Oncol"},{"key":"3_CR4","unstructured":"Arora T, Mullangi S, Lekkala MR (2023). Ovarian Cancer. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; PMID: 33620837."},{"key":"3_CR5","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1016\/j.exer.2008.03.019","volume":"88","author":"HH Arts","year":"2009","unstructured":"Arts HH, Cremers FP, Knoers NV, Roepman R (2009). Focus on molecules: RPGRIP1. Exp Eye Res 88:332\u2013333.","journal-title":"Exp Eye Res"},{"key":"3_CR6","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1038\/nrg1557","volume":"6","author":"JL Badano","year":"2005","unstructured":"Badano JL, Teslovich TM, Katsanis N (2005). The centrosome in human genetic disease. Nat Rev Genet 6:194\u2013205.","journal-title":"Nat Rev Genet"},{"key":"3_CR7","doi-asserted-by":"publisher","first-page":"3985","DOI":"10.1002\/j.1460-2075.1989.tb08581.x","volume":"8","author":"E Bailly","year":"1989","unstructured":"Bailly E, Dor\u00e9e M, Nurse P, Bornens M (1989). P34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2\/M and enters vesicles at anaphase. EMBO J 8:3985\u20133995.","journal-title":"EMBO J"},{"key":"3_CR8","doi-asserted-by":"publisher","first-page":"3469","DOI":"10.1242\/jcs.115.17.3469","volume":"115","author":"JB Barlow","year":"2002","unstructured":"Barlow JB, Gonzalez-Garay ML, Cabral F (2002). Paclitaxel-dependent mutants have severely reduced microtubule assembly and reduced tubulin synthesis. J Cell Sci 115:3469\u20133478.","journal-title":"J Cell Sci"},{"key":"3_CR9","doi-asserted-by":"publisher","first-page":"2987","DOI":"10.1242\/jcs.013136","volume":"120","author":"AR Barr","year":"2007","unstructured":"Barr AR, Gergely F (2007). Aurora A: the maker and breaker of spindle poles. J Cell Sci 120:2987\u20132996.","journal-title":"J Cell Sci"},{"key":"3_CR10","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1006\/geno.2000.6462","volume":"72","author":"L Bartoloni","year":"2001","unstructured":"Bartoloni L, Blouin JL, Maiti AK, et al (2001). Axonemal beta heavy chain dynein DNAH9: cDNA sequence, genomic structure, and investigation of its role in primary ciliary dyskinesia. Genomics 72:21\u201333.","journal-title":"Genomics"},{"key":"3_CR11","doi-asserted-by":"publisher","first-page":"R526","DOI":"10.1016\/j.cub.2009.05.025","volume":"19","author":"NF Berbari","year":"2009","unstructured":"Berbari NF, O\u2019Connor AK, Haycraft CJ, Yoder BK (2009). The primary cilium as a complex signaling center. Curr Biol 19:R526\u2013535.","journal-title":"Curr Biol"},{"key":"3_CR12","volume-title":"The centrosome, Chap 11","author":"R Boutros","year":"2012","unstructured":"Boutros R (2012). Regulation of centrosomes by cyclin-dependent kinases. In: Schatten H, editor. The centrosome, Chap 11. New York: Springer Science and Business Media."},{"key":"3_CR13","volume-title":"Zur Frage der Entstehung maligner Tumoren","author":"T Boveri","year":"1914","unstructured":"Boveri T. (1914). Zur Frage der Entstehung maligner Tumoren. Jena: G. Fisher."},{"key":"3_CR14","doi-asserted-by":"crossref","unstructured":"Boveri T (2008). Concerning the origin of malignant tumours by Theodor Boveri (Translated and annotated by Henry Harris). J Cell Sci. 2008;121 Suppl 1:1\u201384.","DOI":"10.1242\/jcs.025742"},{"key":"3_CR15","doi-asserted-by":"publisher","unstructured":"Br\u00fcning-Richardson A, Bond J, Alsiary R, Richardson J, Cairns DA, McCormac L, Hutson R, Burns PA, Wilkinson N, Hall GD, Morrison EE, Bell SM (2012). NuMA overexpression in epithelial ovarian cancer. PLoS One 7(6):e38945. https:\/\/doi.org\/10.1371\/journal.pone.0038945. PMID: 22719996; PMCID: PMC3375276.","DOI":"10.1371\/journal.pone.0038945"},{"key":"3_CR16","volume":"201","author":"SM Campos","year":"2010","unstructured":"Campos SM, Ghosh S (2010). A current review of targeted therapeutics for ovarian cancer. J Oncol 201:149362.","journal-title":"J Oncol"},{"issue":"1","key":"3_CR17","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1021\/mp900138a","volume":"7","author":"MS Cartiera","year":"2009","unstructured":"Cartiera MS, Ferreira EC, Caputo C, Egan ME, Caplan MJ, Saltzman WM (2009). Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin. Mol Pharm 7(1):86\u201393.","journal-title":"Mol Pharm"},{"key":"3_CR18","doi-asserted-by":"publisher","first-page":"R788","DOI":"10.1186\/bcr1304","volume":"7","author":"I Carvalho","year":"2005","unstructured":"Carvalho I, Milanezi F, Martins A, Reis RM, Schmitt F (2005). Overexpression of platelet-derived growth factor receptor alpha in breast cancer is associated with tumour progression. Breast Cancer Res 7:R788\u2013795.","journal-title":"Breast Cancer Res"},{"key":"3_CR19","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/S1534-5807(03)00193-X","volume":"5","author":"M Casenghi","year":"2003","unstructured":"Casenghi M, Meraldi P, Weinhart U, Duncan PI, Korner R, Nigg EA (2003). Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation. Dev Cell 5:113\u2013125","journal-title":"Dev Cell"},{"key":"3_CR20","doi-asserted-by":"crossref","unstructured":"Chan JY (2011). A clinical overview of centrosome amplification in human cancers. Int J Biol Sci 7(8):1122\u20131144.","DOI":"10.7150\/ijbs.7.1122"},{"issue":"3","key":"3_CR21","first-page":"1","volume":"2","author":"A D\u2019Angelo","year":"2009","unstructured":"D\u2019Angelo A, Franco B (2009). The dynamic cilium in human diseases. Patho Genetics 2(3):1\u201315.","journal-title":"Patho Genetics"},{"key":"3_CR22","doi-asserted-by":"publisher","DOI":"10.1038\/oncsis.2013.34","volume":"2","author":"TK Das","year":"2013","unstructured":"Das TK, Dana D, Paroly SS, Perumal SK, Singh S, Jhun H, Pendse J, Cagan RL, Talele TT, Kumar S (2013). Centrosomal kinase Nek2 cooperates with oncogenic pathways to promote metastasis. Oncogenesis 2, e69; https:\/\/doi.org\/10.1038\/oncsis.2013.34","journal-title":"Oncogenesis"},{"key":"3_CR23","doi-asserted-by":"publisher","first-page":"4068","DOI":"10.1038\/sj.onc.1207568","volume":"23","author":"AB D\u2019Assoro","year":"2004","unstructured":"D\u2019Assoro AB, Busby R, Suino K, et al (2004). Genotoxic stress leads to centrosome amplification in breast cancer cell lines that have an inactive G1\/S cell cycle checkpoint. Oncogene 23:4068\u20134075.","journal-title":"Oncogene"},{"key":"3_CR24","doi-asserted-by":"publisher","first-page":"3901","DOI":"10.1038\/onc.2008.18","volume":"27","author":"AB D\u2019Assoro","year":"2008","unstructured":"D\u2019Assoro AB, Busby R, Acu ID, et al (2008). Impaired p53 function leads to centrosome amplification, acquired ER alpha phenotypic heterogeneity and distant metastases in breast cancer MCF-7 xenografts. Oncogene 27:3901\u20133911.","journal-title":"Oncogene"},{"key":"3_CR25","doi-asserted-by":"publisher","first-page":"F1159","DOI":"10.1152\/ajprenal.00118.2005","volume":"289","author":"JR Davenport","year":"2005","unstructured":"Davenport JR, Yoder BK (2005). An incredible decade for the primary cilium: a look at a once forgotten organelle. Am J Physiol Renal Physiol 289:F1159\u20131169.","journal-title":"Am J Physiol Renal Physiol"},{"key":"3_CR26","doi-asserted-by":"publisher","first-page":"5608","DOI":"10.1073\/pnas.78.9.5608","volume":"78","author":"M De Brabander","year":"1981","unstructured":"De Brabander M, Geuens G, Nuydens R, Willebrords R, De Mey J (1981). Taxol induces the assembly of free microtubules in living cells and blocks the organizing capacity of the centrosomes and kinetochores. Proc Natl Acad Sci USA 78:5608\u201312.","journal-title":"Proc Natl Acad Sci USA"},{"issue":"20","key":"3_CR27","doi-asserted-by":"publisher","first-page":"8035","DOI":"10.1158\/0008-5472.CAN-09-1224","volume":"69","author":"S De","year":"2009","unstructured":"De S, Cipriano R, Jackson MW, Stark G R (2009). Overexpression of kinesins mediates docetaxel resistance in breast cancer cells. Cancer Res 69(20):8035\u20138042.","journal-title":"Cancer Res"},{"key":"3_CR28","doi-asserted-by":"publisher","first-page":"2575","DOI":"10.1039\/C2NR11502F","volume":"4","author":"S Dev","year":"2012","unstructured":"Dev S, Prabhakaran P, Filgueira L, Iyer KS, Raston CL (2012). Microfluidic fabrication of cationic curcumin nanoparticles as an anti-cancer agent. Nanoscale 4:2575\u20132579.","journal-title":"Nanoscale"},{"key":"3_CR29","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1083\/jcb.141.1.163","volume":"141","author":"J Dictenberg","year":"1998","unstructured":"Dictenberg J, Zimmerman W, Sparks C, Young A, Vidair C, Zheng Y, Carrington W, Fay F, Doxsey SJ (1998). Pericentrin and gamma tubulin form a protein complex and are organized into a novel lattice at the centrosome. J Cell Biol 141:163\u2013174.","journal-title":"J Cell Biol"},{"key":"3_CR30","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1111\/j.1440-1835.2001.tb00229.x","volume":"49","author":"I Dimitriadis","year":"2001","unstructured":"Dimitriadis I, Katsaros C, Galatis B (2001). The effect of taxol on centrosome function and microtu bule organization in apical cells of Sphacelaria rigidula (Phaeophyceae). Phycol Res 49:23\u201334.","journal-title":"Phycol Res"},{"key":"3_CR31","doi-asserted-by":"publisher","first-page":"2357","DOI":"10.1242\/jcs.114.13.2357","volume":"114","author":"MM Donaldson","year":"2001","unstructured":"Donaldson MM, Tavares AAM, Hagan IM, Nigg EA, Glover DM (2001). The mitotic roles of polo like kinase. J Cell Sci 114:2357\u20132358.","journal-title":"J Cell Sci"},{"key":"3_CR32","doi-asserted-by":"crossref","unstructured":"Doxsey SJ, Stein P, Evans L, Calarco P, Kirschner M (1994). Pericentrin, a highly conserved protein of centrosomes involved in microtubule organization. Cell 76:639\u2013650.","DOI":"10.1016\/0092-8674(94)90504-5"},{"key":"3_CR33","doi-asserted-by":"publisher","unstructured":"Dr\u00e1ber P, Dr\u00e1berov\u00e1 E (2021). Dysregulation of Microtubule Nucleating Proteins in Cancer Cells. Cancers (Basel) 13(22):5638. https:\/\/doi.org\/10.3390\/cancers13225638. PMID: 34830792; PMCID: PMC8616210.","DOI":"10.3390\/cancers13225638"},{"key":"3_CR34","doi-asserted-by":"publisher","first-page":"10002","DOI":"10.1073\/pnas.170093297","volume":"97","author":"S Duensing","year":"2000","unstructured":"Duensing S, Lee LY, Duensing A, Basile J, Piboonniyom S, Gonzalez S, Crum CP, Munger K (2000). The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle. Proc Natl Acad Sci USA 97:10002\u201310007.","journal-title":"Proc Natl Acad Sci USA"},{"key":"3_CR35","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2020.620185","volume":"11","author":"H Ebisu","year":"2021","unstructured":"Ebisu H, Shintani K, Chinen T, Nagumo Y, Shioda S, Hatanaka T, Sakakura A, Hayakawa I, Kigoshi H, Usui T (2021) Dual Inhibition of \u03b3-Tubulin and Plk1 Induces Mitotic Cell Death. Front Pharmacol 11:620185. https:\/\/doi.org\/10.3389\/fphar.2020.620185","journal-title":"Front Pharmacol"},{"key":"3_CR36","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/2046-2530-1-15","volume":"1","author":"DL Egeberg","year":"2012","unstructured":"Egeberg DL, Lethan M, Manguso R, Schneider L, Awan A, J\u00f8rgensen TS, Byskov AG, Pedersen LB, Christensen ST (2012). Primary cilia and aberrant cell signaling in epithelial ovarian cancer. Cilia 1:15. https:\/\/doi.org\/10.1186\/2046-2530-1-15","journal-title":"Cilia"},{"key":"3_CR37","doi-asserted-by":"publisher","first-page":"1882","DOI":"10.1126\/science.286.5446.1882","volume":"286","author":"L Ellgaard","year":"1999","unstructured":"Ellgaard L, Molinari M, Helenius A (1999). Setting the standards: quality control in the secretory pathway. Science 286:1882\u20131888.","journal-title":"Science"},{"key":"3_CR38","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1002\/mrd.10283","volume":"65","author":"H-Y Fan","year":"2003","unstructured":"Fan H-Y, Tong C, Teng C-B, Lian L, Li S-W, Yang Z-M, Chen D-Y, Schatten H, Sun Q-Y (2003). Characterization of Polo-like kinase-1 in rat oocytes and early embryos implies its functional roles in the regulation of meiotic maturation, fertilization and cleavage. Mol Reprod Dev 65:318\u2013329.","journal-title":"Mol Reprod Dev"},{"key":"3_CR39","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1038\/363637a0","volume":"363","author":"B Fenton","year":"1993","unstructured":"Fenton B, Glover DM (1993). A conserved mitotic kinase active at late anaphase-telophase in syncytial Drosophila embryos. Nature 363:637\u2013640.","journal-title":"Nature"},{"key":"3_CR40","volume-title":"The centrosome, Chap 8","author":"HA Fisk","year":"2012","unstructured":"Fisk HA (2012). Many pathways to destruction: the centrosome and its control by and role in regulated proteolysis. In: Schatten H, editor. The centrosome, Chap 8. New York: Springer Science and Business Media."},{"key":"3_CR41","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1016\/S0888-7543(03)00119-8","volume":"82","author":"MR Flory","year":"2003","unstructured":"Flory MR, Davis TN (2003). The centrosomal proteins pericentrin and kendrin are encoded by alter natively spliced products of one gene. Genomics 82:401\u2013405.","journal-title":"Genomics"},{"key":"3_CR42","doi-asserted-by":"publisher","first-page":"2242","DOI":"10.1101\/gad.13.17.2242","volume":"13","author":"E Freed","year":"1999","unstructured":"Freed E, Lacey KR, Huie P, Lyapina SA, Deshaies RJ, Stearns T, Jackson PK (1999). Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle. Genes Dev 13:2242\u20132257.","journal-title":"Genes Dev"},{"key":"3_CR43","doi-asserted-by":"crossref","unstructured":"Fry AM, Mayor T, Meraldi P, Stierhof YD, Tanaka K, Nigg EA (1998). C-NAP1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2. J Cell Biol 141:1563\u20131574. PMID: 2133000","DOI":"10.1083\/jcb.141.7.1563"},{"key":"3_CR44","doi-asserted-by":"publisher","first-page":"6184","DOI":"10.1038\/sj.onc.1205711","volume":"21","author":"AM Fry","year":"2002","unstructured":"Fry AM (2002). The Nek2 protein kinase: a novel regulator of centrosome structure. Oncogene 21:6184\u20136194.","journal-title":"Oncogene"},{"key":"3_CR45","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1002\/3527603808.ch8","volume-title":"Centrosomes in development and disease","author":"AM Fry","year":"2004","unstructured":"Fry AM, Hames RS (2004). The role of the centrosome in cell cycle progression. In: Nigg E, editor. Centrosomes in development and disease. Weinheim: Wiley-VCA; p. 143\u201366."},{"key":"3_CR46","doi-asserted-by":"publisher","unstructured":"Fry AM, O\u2019Regan L, Sabir SR, Bayliss R (2012). Cell cycle regulation by the NEK family of protein kinases. J Cell Sci 125:4423\u20134433. PMID: 3500863. https:\/\/doi.org\/10.1242\/jcs.111195","DOI":"10.1242\/jcs.111195"},{"key":"3_CR47","doi-asserted-by":"publisher","first-page":"1622","DOI":"10.12688\/f1000research.11652.1","volume":"6","author":"AM Fry","year":"2017","unstructured":"Fry AM, Sampson J, Shak C, Shackleton S (2017). Recent advances in pericentriolar material organization: Ordered layers and scaffolding gels. F1000Research 6, 1622.","journal-title":"F1000Research"},{"key":"3_CR48","volume-title":"The centrosome, Chap 10","author":"K Fukasawa","year":"2012","unstructured":"Fukasawa K (2012). Molecular links between centrosome duplication and other cell cycle associated events. In: Schatten H, editor. The centrosome, Chap 10. New York: Springer Science and Business Media."},{"issue":"7252","key":"3_CR49","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1038\/nature08136","volume":"460","author":"NJ Ganem","year":"2009","unstructured":"Ganem NJ, Godinho SA, Pellman D (2009). A mechanism linking extra centrosomes to chromosomal instability. Nature 460(7252):278\u201382.","journal-title":"Nature"},{"key":"3_CR50","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1038\/sj.embor.7400046","volume":"5","author":"KL Gehmlich","year":"2004","unstructured":"Gehmlich KL, Haren L, Merdes A (2004). Cyclin B degradation leads to NuMA release from dynein\/dynactin and from spindle poles. EMBO Rep 5:97\u2013103.","journal-title":"EMBO Rep"},{"issue":"22","key":"3_CR51","doi-asserted-by":"publisher","first-page":"2291","DOI":"10.1101\/gad.1715208","volume":"2008","author":"F Gergely","year":"2008","unstructured":"Gergely F, Basto R (2008). Multiple centrosomes: together they stand, divided they fall. Genes Dev 2008(22):2291\u20132296.","journal-title":"Genes Dev"},{"key":"3_CR52","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1093\/embo-reports\/kvd105","volume":"1","author":"AK Gillingham","year":"2000","unstructured":"Gillingham AK, Munro S (2000). The PACT domain, a conserved centrosomal targeting motif in the coiled-coil proteins AKAP450 and pericentrin. EMBO Rep 1:524\u2013529.","journal-title":"EMBO Rep"},{"key":"3_CR53","first-page":"4115","volume":"62","author":"TM Goepfert","year":"2002","unstructured":"Goepfert TM, Adigun YE, Zhong L, et al (2002). Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis. Cancer Res 62:4115\u20134122.","journal-title":"Cancer Res"},{"key":"3_CR54","doi-asserted-by":"publisher","first-page":"1617","DOI":"10.1083\/jcb.129.6.1617","volume":"129","author":"RM Golsteyn","year":"1995","unstructured":"Golsteyn RM, Mundt KE, Fry AM, Nigg EA (1995). Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function. J Cell Biol 129:1617\u20131628.","journal-title":"J Cell Biol"},{"key":"3_CR55","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1038\/244294a0","volume":"244","author":"LM Grisham","year":"1973","unstructured":"Grisham LM, Wilson L, Bensch KG (1973). Antimitotic action of griseofulvin does not involve disruption of microtubules. Nature 244:294\u2013296.","journal-title":"Nature"},{"key":"3_CR56","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1006\/excr.1999.4386","volume":"247","author":"M Gstaiger","year":"1999","unstructured":"Gstaiger M, Marti A, Krek W (1999). Association of human SCF(SKP2) subunit p19(SKP1) with interphase centrosomes and mitotic spindle poles. Exp Cell Res 247:554\u2013562.","journal-title":"Exp Cell Res"},{"key":"3_CR57","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1083\/jcb.200202047","volume":"157","author":"E Hannak","year":"2002","unstructured":"Hannak E, Oegema K, Kirkham M, Gonczy P, Habermann B, Hyman AA (2002). The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is \u03b3-tubulin dependent. J Cell Biol 157:591\u2013602.","journal-title":"J Cell Biol"},{"key":"3_CR58","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.0010053","volume":"1","author":"CJ Haycraft","year":"2005","unstructured":"Haycraft CJ, Banizs B, Aydin-Son Y, et al (2005). Gli2 and gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function. PLoS Genet 1:e53.","journal-title":"PLoS Genet"},{"key":"3_CR59","doi-asserted-by":"publisher","first-page":"7370","DOI":"10.1158\/0008-5472.CAN-04-0960","volume":"64","author":"DG Hayward","year":"2004","unstructured":"Hayward DG, Clarke RB, Faragher AJ, et al (2004). The centrosomal kinase Nek2 displays elevated levels of protein expression in human breast cancer. Cancer Res 64:7370\u20137376.","journal-title":"Cancer Res"},{"key":"3_CR60","doi-asserted-by":"publisher","unstructured":"Hayward DG, Fry AM (2006). NEK2 kinase in chromosome instability and cancer. Cancer Lett 237:155\u2013166. PMID:16084011. https:\/\/doi.org\/10.1016\/j.canlet.2005.06.017.","DOI":"10.1016\/j.canlet.2005.06.017"},{"key":"3_CR61","doi-asserted-by":"publisher","unstructured":"Henise JC, Taunton J (2011). Irreversible NEK2 kinase inhibitors with cellular activity. J Med Chem 54:4133\u20134146. PMID:3663048. https:\/\/doi.org\/10.1021\/jm200222m","DOI":"10.1021\/jm200222m"},{"key":"3_CR62","first-page":"4550","volume":"53","author":"R Henriksen","year":"1993","unstructured":"Henriksen R, Funa K, Wilander E, Backstrom T, Ridderheim M, Oberg K (1993). Expression and prognostic significance of platelet-derived growth factor and its receptors in epithelial ovarian neoplasms. Cancer Res 53:4550\u20134554.","journal-title":"Cancer Res"},{"key":"3_CR63","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1038\/nrg1727","volume":"6","author":"F Hildebrandt","year":"2005","unstructured":"Hildebrandt F, Otto E (2005). Cilia and centrosomes: a unifying pathogenic concept for cystic kidney disease? Nat Rev Genet 6:928\u2013940.","journal-title":"Nat Rev Genet"},{"key":"3_CR64","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1002\/1097-0215(200002)9999:9999<::AID-IJC1070>3.0.CO;2-#","volume":"91","author":"YS Ho","year":"2001","unstructured":"Ho YS, Duh JS, Jeng JH, Wang YJ, Liang YC, Lin CH, Tseng CJ, Yu CF, Chen RJ, Lin JK (2001). Griseofulvin potentiates antitumorigenesis effects of nocodazole through induction of apoptosis and G2\/M cell cycle arrest in human colorectal cancer cells. Int J Cancer 91:393\u2013401.","journal-title":"Int J Cancer"},{"key":"3_CR65","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1002\/ijc.20633","volume":"113","author":"LC Hsu","year":"2005","unstructured":"Hsu LC, Kapali M, DeLoia JA, Gallion HH (2005). Centrosome abnormalities in ovarian cancer. Int J Cancer 113:746\u2013751.","journal-title":"Int J Cancer"},{"key":"3_CR66","doi-asserted-by":"crossref","unstructured":"Hu Y, Zheng M, Wang C, Wang S, Gou R, Liu O, Li X, Liu J, Lin B (2020). Identification of KIF23 as a prognostic signature for ovarian cancer based on large-scale sampling and clinical validation. Am J Transl Res 12(9):4955\u20134976. PMID: 33042400; PMCID: PMC7540138.","DOI":"10.21203\/rs.2.23036\/v1"},{"key":"3_CR67","doi-asserted-by":"publisher","first-page":"2184","DOI":"10.1093\/emboj\/18.8.2184","volume":"18","author":"J Huang","year":"1999","unstructured":"Huang J, Raff JW (1999). The disappearance of cyclin B at the end of mitosis is regulated spatially in Drosophila cells. EMBO J 18:2184\u20132195.","journal-title":"EMBO J"},{"issue":"3","key":"3_CR68","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1083\/jcb.201106101","volume":"197","author":"A Inoko","year":"2012","unstructured":"Inoko A, Matsuyama M, Goto H, Ohmuro-Matsuyama Y, Hayashi Y, Enomoto M, Ibi M, Urano T, Yonemura S, Kiyono T, Izawa I, Inagaki M (2012). Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells. J Cell Biol 197(3):391\u2013405.","journal-title":"J Cell Biol"},{"key":"3_CR69","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1038\/ncb918","volume":"5","author":"M Jackman","year":"2003","unstructured":"Jackman M, Lindon C, Nigg E, Pines J (2003). Active cyclin B1-Cdk1 first appears on centrosomes in prophase. Nat Cell Biol 5:143\u2013148.","journal-title":"Nat Cell Biol"},{"issue":"9951","key":"3_CR70","doi-asserted-by":"publisher","first-page":"1376","DOI":"10.1016\/S0140-6736(13)62146-7","volume":"384","author":"GC Jayson","year":"2014","unstructured":"Jayson GC, Kohn EC, Kitchener HC, Ledermann JA (2014). Ovarian cancer. Lancet. 384 (9951):1376\u20131388.","journal-title":"Lancet"},{"key":"3_CR71","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.1172\/JCI24652","volume":"116","author":"M Jechlinger","year":"2006","unstructured":"Jechlinger M, Sommer A, Moriggl R, et al (2006). Autocrine PDGFR signaling promotes mammary cancer metastasis. J Clin Invest 116:1561\u20131570.","journal-title":"J Clin Invest"},{"key":"3_CR72","doi-asserted-by":"publisher","first-page":"2065","DOI":"10.1158\/1078-0432.CCR-1057-03","volume":"10","author":"YM Jeng","year":"2004","unstructured":"Jeng YM, Peng SY, Lin CY, Hsu HC (2004). Overexpression and amplification of Aurora-A in hepatocellular carcinoma. Clin Cancer Res 10:2065\u20132071.","journal-title":"Clin Cancer Res"},{"key":"3_CR73","doi-asserted-by":"publisher","first-page":"1883","DOI":"10.1083\/jcb.143.7.1883","volume":"143","author":"JA Johnston","year":"1998","unstructured":"Johnston JA, Ward CL, Kopito RR (1998). Aggresomes: a cellular response to misfolded proteins. J Cell Biol 143:1883\u20131898.","journal-title":"J Cell Biol"},{"key":"3_CR74","volume-title":"The centrosome, Chap 14","author":"Z Kais","year":"2012","unstructured":"Kais Z, Parvin JD (2012). Centrosome regulation and breast cancer. In: Schatten H, editor. The centrosome, Chap 14. New York: Springer Science and Business Media."},{"issue":"6","key":"3_CR75","doi-asserted-by":"publisher","first-page":"2004","DOI":"10.1073\/pnas.0409806102","volume":"102","author":"S Kammerer","year":"2005","unstructured":"Kammerer S, Roth RB, Hoyal CR, Reneland R, Marnellos G, Kiechle M, Schwarz-Boeger U, Griffiths LR, Ebner F, Rehbock J, Cantor CR, Nelson MR, Brown A (2005). Association of the NuMA region on chromosome 11q13 with breast cancer susceptibility. Proc Natl Acad Sci USA 102(6):2004\u20132009.","journal-title":"Proc Natl Acad Sci USA"},{"key":"3_CR76","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/j.ejca.2005.08.039","volume":"42","author":"M Kasper","year":"2006","unstructured":"Kasper M, Regl G, Frischauf AM, Aberger F (2006). GLI transcription factors: mediators of onco genic Hedgehog signalling. Eur J Cancer 42:437\u2013445.","journal-title":"Eur J Cancer"},{"key":"3_CR77","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1023\/A:1023789416385","volume":"22","author":"H Katayama","year":"2003","unstructured":"Katayama H, Brinkley WR, Sen S (2003). The Aurora kinases: role in cell transformation and tumorigenesis. Cancer Metastasis Rev 22:451\u2013464.","journal-title":"Cancer Metastasis Rev"},{"key":"3_CR78","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1091\/mbc.e03-03-0191","volume":"15","author":"S Kawaguchi","year":"2004","unstructured":"Kawaguchi S, Zheng Y (2004). Characterization of a Drosophila centrosome protein CP309 that shares homology with Kendrin and CG-NAP. Mol Biol Cell 15:37\u201345.","journal-title":"Mol Biol Cell"},{"key":"3_CR79","doi-asserted-by":"publisher","first-page":"4260","DOI":"10.1091\/mbc.e02-11-0773","volume":"14","author":"G Keryer","year":"2003","unstructured":"Keryer G, Di Fiore B, Celati C, Lechtreck KF, Mogensen M, Delouvee A, Lavia P, Bornens M, Tassin AM (2003). Part of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity. Mol Biol Cell 14:4260\u20134271.","journal-title":"Mol Biol Cell"},{"key":"3_CR80","doi-asserted-by":"publisher","unstructured":"Khedkar HN, Wang YC, Yadav VK, Srivastava P, Lawal B, Mokgautsi N, Sumitra MR, Wu ATH, Huang HS (2021). In-Silico Evaluation of Genetic Alterations in Ovarian Carcinoma and Therapeutic Efficacy of NSC777201, as a Novel Multi-Target Agent for TTK, NEK2, and CDK1. Int J Mol Sci 22(11):5895. https:\/\/doi.org\/10.3390\/ijms22115895. PMID: 34072728; PMCID: PMC8198179.","DOI":"10.3390\/ijms22115895"},{"key":"3_CR81","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1038\/sj.onc.1209028","volume":"25","author":"MJ Ko","year":"2006","unstructured":"Ko MJ, Murata K, Hwang DS, et al (2006). Inhibition of BRCA1 in breast cell lines causes the centrosome duplication cycle to be disconnected from the cell cycle. Oncogene 25:298\u2013303.","journal-title":"Oncogene"},{"key":"3_CR82","doi-asserted-by":"publisher","unstructured":"Kokuryo T, Yokoyama Y, Yamaguchi J, Tsunoda N, Ebata T, Nagino M (2019). NEK2 Is an Effective Target for Cancer Therapy With Potential to Induce Regression of Multiple Human Malignancies. Anticancer Res 39(5):2251\u20132258. https:\/\/doi.org\/10.21873\/anticanres.13341. PMID: 31092416.","DOI":"10.21873\/anticanres.13341"},{"key":"3_CR83","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1016\/S0962-8924(00)01852-3","volume":"10","author":"RR Kopito","year":"2000","unstructured":"Kopito RR (2000). Aggresomes, inclusion bodies and protein aggregation. Trends Cell Biol 10:524\u2013530.","journal-title":"Trends Cell Biol"},{"key":"3_CR84","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1186\/1476-4598-9-153","volume":"9","author":"N Korzeniewski","year":"2010","unstructured":"Korzeniewski N, Wheeler S, Chatterjee P, et al (2010). A novel role of the aryl hydrocarbon receptor (AhR) in centrosome amplification\u2014implications for chemoprevention. Mol Cancer 9:153.","journal-title":"Mol Cancer"},{"key":"3_CR85","volume-title":"The centrosome, Chap 12","author":"N Korzeniewski","year":"2012","unstructured":"Korzeniewski N, Duensing S (2012). Disruption of centrosome duplication control and induction of mitotic instability by the high-risk human papillomavirus oncoproteins E6 and E7. In: Schatten H, editor. The centrosome, Chap 12. New York: Springer Science and Business Media."},{"issue":"4","key":"3_CR86","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1016\/j.molonc.2011.05.003","volume":"5","author":"A Kr\u00e4mer","year":"2011","unstructured":"Kr\u00e4mer, A., Maier, B., and Bartek, J. (2011). Centrosome clustering and chromosomal (in)stability: A matter of life and death. Mol Oncol 5(4):324\u2013335.","journal-title":"Mol Oncol"},{"key":"3_CR87","volume-title":"The centrosome, Chap 17","author":"A Kr\u00e4mer","year":"2012","unstructured":"Kr\u00e4mer A, Anderhub S, Maier B (2012). Mechanisms and consequences of centrosome clustering in cancer cells. In: Schatten H, editor. The centrosome, Chap 17. New York: Springer Science and Business Media."},{"key":"3_CR88","doi-asserted-by":"publisher","first-page":"1555","DOI":"10.1091\/mbc.11.5.1555","volume":"11","author":"ER Kramer","year":"2000","unstructured":"Kramer ER, Scheuringer N, Podtelejnikov AV, Mann M, Peters JM (2000). Mitotic regulation of the APC activator proteins CDC20 and CDH1. Mol Biol Cell 11:1555\u20131569.","journal-title":"Mol Biol Cell"},{"key":"3_CR89","doi-asserted-by":"publisher","first-page":"2189","DOI":"10.1101\/gad.1700908","volume":"22","author":"M Kwon","year":"2008","unstructured":"Kwon M, Godinho SA, Chandhok NS, Ganem NJ, Azioune A, Thery M, Pellman D (2008). Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes. Genes Dev 22:2189\u20132203.","journal-title":"Genes Dev"},{"key":"3_CR90","doi-asserted-by":"publisher","first-page":"4098","DOI":"10.1158\/1078-0432.CCR-07-0431","volume":"13","author":"CN Landen Jr","year":"2007","unstructured":"Landen Jr CN, Lin YG, Immaneni A, Deavers MT, Merritt WM, Spannuth WA, Bodurka DC, Gershenson DM, Brinkley WR, Sood AK (2007). Overexpression of the Centrosomal Protein Aurora-A Kinase is Associated with Poor Prognosis in Epithelial Ovarian Cancer Patients. Clin Cancer Res 13:4098\u20134104.","journal-title":"Clin Cancer Res"},{"key":"3_CR91","doi-asserted-by":"publisher","first-page":"2048","DOI":"10.1038\/sj.bjc.6602252","volume":"91","author":"H Lassus","year":"2004","unstructured":"Lassus H, Sihto H, Leminen A, Nordling S, Joensuu H, Nupponen NN, Butzow R (2004). Genetic alterations and protein expression of KIT and PDGFRA in serous ovarian carcinoma. Br J Cancer 91:2048\u20132055.","journal-title":"Br J Cancer"},{"key":"3_CR92","doi-asserted-by":"crossref","unstructured":"Leber, B., Maier, B., Fuchs, F., Chi, J., Riffel, P., Anderhub, S., Wagner, L., Ho, A. D., Salisbury, J. L., Boutros, M., and Kr\u00e4mer, A. (2010). Proteins required for centrosome clustering in cancer cells. Sci Transl Med 2(33).","DOI":"10.1126\/scitranslmed.3000915"},{"key":"3_CR93","doi-asserted-by":"publisher","unstructured":"Lee J, Gollahon L (2013). NEK2-targeted ASO or siRNA pretreatment enhances anticancer drug sensitivity in triple-negative breast cancer cells. Int J Oncol 42:839\u2013847. PMID: 3597451. https:\/\/doi.org\/10.3892\/ijo.2013.1788","DOI":"10.3892\/ijo.2013.1788"},{"key":"3_CR94","doi-asserted-by":"publisher","unstructured":"Lee MY, Moreno CS, Saavedra HI (2014). E2F activators signal and maintain centrosome amplification in breast cancer cells. Mol Cell Biol 34: 2581\u20132599. PMID: 4097658. https:\/\/doi.org\/10.1128\/MCB.01688-13","DOI":"10.1128\/MCB.01688-13"},{"key":"3_CR95","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1002\/(SICI)1097-0169(1996)33:4<298::AID-CM6>3.0.CO;2-5","volume":"33","author":"YY Levy","year":"1996","unstructured":"Levy YY, Lai EY, Remillard SP, Heintzelman MB, Fulton C (1996). Centrin is a conserved protein that forms diverse associations with centrioles and MTOCs in Naegleria and other organisms. Cell Motil Cytoskeleton 33:298\u2013323.","journal-title":"Cell Motil Cytoskeleton"},{"key":"3_CR96","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1186\/1471-2407-5-7","volume":"5","author":"YW Li","year":"2005","unstructured":"Li YW, Hussain M, Sarkar SH, Eliason J, Li R, Sarkar FH (2005). Gene expression profiling revealed novel mechanism of action of Taxotere and Furtulon in prostate cancer cells. BMC Cancer 5:7.","journal-title":"BMC Cancer"},{"key":"3_CR97","doi-asserted-by":"publisher","first-page":"1316","DOI":"10.1080\/15384047.2015.1070980","volume":"16","author":"Y Li","year":"2015","unstructured":"Li Y, Lu W, Chen D, Boohaker RJ, Zhai L, Padmalayam I, Wennerberg K, Xu B, Zhang W (2015) KIFC1 is a novel potential therapeutic target for breast cancer. Cancer Biol Ther 16:1316\u20131322","journal-title":"Cancer Biol Ther"},{"key":"3_CR98","doi-asserted-by":"publisher","unstructured":"Li J, Diao H, Guan X, Tian X (2020). Kinesin Family Member C1 (KIFC1) Regulated by Centrosome Protein E (CENPE) Promotes Proliferation, Migration, and Epithelial-Mesenchymal Transition of Ovarian Cancer. Med Sci Monit 26:e927869. https:\/\/doi.org\/10.12659\/MSM.927869. PMID: 33361741; PMCID: PMC7780892.","DOI":"10.12659\/MSM.927869"},{"key":"3_CR99","doi-asserted-by":"publisher","unstructured":"Lin S, Zhou S, Jiang S, Liu X, Wang Y, Zheng X, Zhou H, Li X, Cai X (2016). NEK2 regulates stem-like properties and predicts poor prognosis in hepatocellular carcinoma. Oncol Rep 36:853\u2013862. PMID: 27349376. https:\/\/doi.org\/10.3892\/or.2016.4896","DOI":"10.3892\/or.2016.4896"},{"key":"3_CR100","doi-asserted-by":"publisher","first-page":"2950","DOI":"10.1073\/pnas.95.6.2950","volume":"95","author":"WL Lingle","year":"1998","unstructured":"Lingle WL, Lutz WH, Ingle JN, Maihle NJ, Salisbury JL (1998). Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity. Proc Natl Acad Sci USA 95:2950\u20132955.","journal-title":"Proc Natl Acad Sci USA"},{"key":"3_CR101","doi-asserted-by":"publisher","first-page":"1941","DOI":"10.1016\/S0002-9440(10)65513-7","volume":"155","author":"WL Lingle","year":"1999","unstructured":"Lingle WL, Salisbury JL (1999). Altered centrosome structure is associated with abnormal mitoses in human breast tumors. Am J Pathol 155:1941\u20131951.","journal-title":"Am J Pathol"},{"key":"3_CR102","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/S0070-2153(99)49015-5","volume":"49","author":"WL Lingle","year":"2000","unstructured":"Lingle WL, Salisbury JL (2000). The role of the centrosome in the development of malignant tumors. Curr Top Dev Biol 49:313\u2013329.","journal-title":"Curr Top Dev Biol"},{"key":"3_CR103","doi-asserted-by":"publisher","first-page":"1978","DOI":"10.1073\/pnas.032479999","volume":"99","author":"WL Lingle","year":"2002","unstructured":"Lingle WL, Barrett SL, Negron VC, D'Assoro AB, Boeneman K, Liu W, Whitehead CM, Reynolds C, Salisbury JL (2002). Centrosome amplification drives chromosomal instability in breast tumor development. Proc Natl Acad Sci USA 99:1978\u20131983.","journal-title":"Proc Natl Acad Sci USA"},{"key":"3_CR104","doi-asserted-by":"publisher","unstructured":"Liu X, Gao Y, Lu Y, Zhang J, Li L, Yin F (2014). Up-regulation of NEK2 is associated with drug resistance in ovarian cancer. Oncol Rep 31:745\u2013754. PMID: 24337664. https:\/\/doi.org\/10.3892\/or.2013.2910","DOI":"10.3892\/or.2013.2910"},{"key":"3_CR105","doi-asserted-by":"publisher","unstructured":"Liu Y, Shen Z, Zhu T, Lu W, Fu Y (2023). Curcumin enhances the anti-cancer efficacy of paclitaxel in ovarian cancer by regulating the miR-9-5p\/BRCA1 axis. Front Pharmacol 13:1014933. https:\/\/doi.org\/10.3389\/fphar.2022.1014933. PMID: 36703740; PMCID: PMC9871306.","DOI":"10.3389\/fphar.2022.1014933"},{"key":"3_CR106","doi-asserted-by":"publisher","first-page":"20774","DOI":"10.1074\/jbc.M101324200","volume":"276","author":"W Lutz","year":"2001","unstructured":"Lutz W, Lingle WL, McCormick D, Greenwood TM, Salisbury JL (2001). Phosphorylation of centrin during the cell cycle and its role in centriole separation preceding centrosome duplication. J Biol Chem 276:20774\u201320780.","journal-title":"J Biol Chem"},{"key":"3_CR107","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1002\/(SICI)1097-0029(20000601)49:5<409::AID-JEMT2>3.0.CO;2-V","volume":"49","author":"GJ Mack","year":"2000","unstructured":"Mack GJ, Ou Y, Rattner JB (2000). Integrating centrosome structure with protein composition and function in animal cells. Microsc Res Tech 49:409\u2013419.","journal-title":"Microsc Res Tech"},{"key":"3_CR108","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1095\/biolreprod.104.031245","volume":"72","author":"G Manandhar","year":"2005","unstructured":"Manandhar G, Schatten H, Sutovsky P (2005). Centrosome reduction during gametogenesis and its significance. Biol Reprod 72:2\u201313.","journal-title":"Biol Reprod"},{"key":"3_CR109","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1093\/mutage\/11.2.195","volume":"11","author":"F Marchetti","year":"1996","unstructured":"Marchetti F, Mailhes JB, Bairnsfather L, Nandy I, London SN (1996). Dose-response study and threshold estimation of griseofulvin induced aneuploidy during female mouse meiosis I and II. Mutagenesis 11:195\u2013200.","journal-title":"Mutagenesis"},{"key":"3_CR110","doi-asserted-by":"crossref","unstructured":"Marina M, Saavedra HI (2014). NEK2 and PLK4: prognostic markers, drivers of breast tumorigenesis and drug resistance. Front Biosci 19:352\u2013365. PMID: 24389189.","DOI":"10.2741\/4212"},{"issue":"14","key":"3_CR111","doi-asserted-by":"publisher","first-page":"3281","DOI":"10.1242\/jcs.094797","volume":"125","author":"V Marthiens","year":"2012","unstructured":"Marthiens, V., Piel, M., and Basto, R. (2012). Never tear us apart - the importance of centrosome clustering. J Cell Sci 125(14):3281\u20133292.","journal-title":"J Cell Sci"},{"key":"3_CR112","doi-asserted-by":"publisher","first-page":"2060","DOI":"10.1038\/sj.onc.1209232","volume":"25","author":"D Matei","year":"2006","unstructured":"Matei D, Emerson RE, Lai YC, Baldridge LA, Rao J, Yiannoutsos C, Donner DD (2006). Autocrine activation of PDGFR alpha promotes the progression of ovarian cancer. Oncogene 25:2060\u20132069.","journal-title":"Oncogene"},{"key":"3_CR113","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1126\/science.1065693","volume":"295","author":"Y Matsumoto","year":"2002","unstructured":"Matsumoto Y, Maller JL (2002). Calcium, calmodulin, and CaMKII requirement for initiation of centrosome duplication in Xenopus egg extracts (comment). Science 295:499\u2013502","journal-title":"Science"},{"key":"3_CR114","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1046\/j.1471-4159.2002.00821.x","volume":"81","author":"KS McNaught","year":"2002","unstructured":"McNaught KS, et al (2002). Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures. J Neurochem 81:301\u2013630.","journal-title":"J Neurochem"},{"key":"3_CR115","doi-asserted-by":"publisher","first-page":"3749","DOI":"10.1242\/jcs.114.20.3749","volume":"114","author":"P Meraldi","year":"2001","unstructured":"Meraldi P and Nigg EA (2001). Centrosome cohesion is regulated by a balance of kinase and phosphatase activities. J Cell Sci 114:3749\u20133757.","journal-title":"J Cell Sci"},{"key":"3_CR116","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1093\/emboj\/21.4.483","volume":"21","author":"P Meraldi","year":"2002","unstructured":"Meraldi P, Honda R, Nigg EA (2002). Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53\u2013\/\u2013 cells. EMBO J 21:483\u2013492.","journal-title":"EMBO J"},{"key":"3_CR117","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1016\/S0092-8674(00)81365-3","volume":"87","author":"A Merdes","year":"1996","unstructured":"Merdes A, Ramyar K, Vechio JD, Cleveland DW (1996). A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly. Cell 87:447\u2013458.","journal-title":"Cell"},{"key":"3_CR118","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1242\/jcs.111.1.71","volume":"111","author":"A Merdes","year":"1998","unstructured":"Merdes A, Cleveland DA (1998). The role of NuMA in the interphase nucleus. J Cell Sci 111:71\u201379.","journal-title":"J Cell Sci"},{"issue":"7","key":"3_CR119","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1002\/em.21717","volume":"53","author":"YL Miao","year":"2012","unstructured":"Miao YL, Zhang X, Zhao JG, Spate L, Zhao MT, Murphy CN, Prather RS, Sun QY, Schatten H (2012). Effects of griseofulvin on in vitro porcine oocyte maturation and embryo development. Environ Mol Mutagen 53(7):561\u20136. https:\/\/doi.org\/10.1002\/em.21717.","journal-title":"Environ Mol Mutagen"},{"key":"3_CR120","doi-asserted-by":"publisher","first-page":"6463","DOI":"10.1158\/0008-5472.CAN-06-0462","volume":"66","author":"EJ Michaud","year":"2006","unstructured":"Michaud EJ, Yoder BK (2006). The primary cilium in cell signaling and cancer. Cancer Res 66:6463\u20136467.","journal-title":"Cancer Res"},{"key":"3_CR121","doi-asserted-by":"publisher","unstructured":"Mignogna C, Staropoli N, Botta C, De Marco C, Rizzuto A, Morelli M, Di Cello A, Franco R, Camastra C, Presta I, Malara N, Salvino A, Tassone P, Tagliaferri P, Barni T, Donato G, Di Vito A (2016). Aurora Kinase A expression predicts platinum-resistance and adverse outcome in high-grade serous ovarian carcinoma patients. J Ovarian Res 9(1):31. https:\/\/doi.org\/10.1186\/s13048-016-0238-7. PMID: 27209210; PMCID: PMC4875597","DOI":"10.1186\/s13048-016-0238-7"},{"key":"3_CR122","doi-asserted-by":"publisher","unstructured":"Mittal K, Choi DH, Klimov S, Pawar S, Kaur R, Mitra AK, Gupta MV, Sams R, Cantuaria G, Rida PCG, Aneja R (2016). A centrosome clustering protein, KIFC1, predicts aggressive disease course in serous ovarian adenocarcinomas. J Ovarian Res 9:17. https:\/\/doi.org\/10.1186\/s13048-016-0224-0. PMID: 26992853; PMCID: PMC5477851.","DOI":"10.1186\/s13048-016-0224-0"},{"key":"3_CR123","doi-asserted-by":"publisher","first-page":"3013","DOI":"10.1242\/jcs.113.17.3013","volume":"113","author":"MM Mogensen","year":"2000","unstructured":"Mogensen MM, Malik A, Piel M, Bouckson-Castaing V, Bornens M (2000). Microtubule minus-end anchorage at centrosomal and non-centrosomal sites: the role of ninein. J Cell Sci 113:3013\u20133023.","journal-title":"J Cell Sci"},{"issue":"8","key":"3_CR124","doi-asserted-by":"publisher","first-page":"2713","DOI":"10.1080\/01635581.2022.2049321","volume":"74","author":"M Mohamadian","year":"2022","unstructured":"Mohamadian M, Bahrami A, Binabaj MM, Asgharzadeh F, Ferns GA (2022). Molecular targets of curcumin and its therapeutic potential for ovarian cancer, Nutrition and Cancer, 74:8, 2713-2730, https:\/\/doi.org\/10.1080\/01635581.2022.2049321","journal-title":"Nutrition and Cancer"},{"key":"3_CR125","doi-asserted-by":"publisher","first-page":"1554","DOI":"10.1038\/sj.onc.1210792","volume":"27","author":"C Montero-Conde","year":"2008","unstructured":"Montero-Conde C, Martin-Camposo JM, Lerma E, Martinez-Guitarte JL, Combalia N, Montaner D, Matias-Guiu X, Dopazo J, de Leiva A, Robledo M et al (2008). Molecular profiling related to poor prognosis in thyroid carcinoma. Combining gene expression data and biological information. Oncogene 27:1554\u20131561.","journal-title":"Oncogene"},{"issue":"6","key":"3_CR126","doi-asserted-by":"publisher","first-page":"2703","DOI":"10.1093\/nar\/gkz138","volume":"47","author":"Moreno","year":"2019","unstructured":"Moreno et al (2019). The nuclear structural protein NuMA is a negative regulator of 53BP1 in DNA double-strand break repair. Nucleic Acids Research, Volume 47, Issue 6, Pages 2703\u20132715, https:\/\/doi.org\/10.1093\/nar\/gkz138","journal-title":"Nucleic Acids Research"},{"issue":"e15670","key":"3_CR127","first-page":"1","volume":"14","author":"Morretton","year":"2022","unstructured":"Morretton et al (2022). A catalog of numerical centrosome defects in epithelial ovarian cancers. EMBO Molecular Medicine 14: e15670, 1\u201312.","journal-title":"EMBO Molecular Medicine"},{"key":"3_CR128","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1002\/3527603808.ch18","volume-title":"Centrosomes in development and disease","author":"K M\u00fcnger","year":"2004","unstructured":"M\u00fcnger K, Duensing S (2004). Radiation therapy and centrosome anomalities in pancreatic cancer. In: Nigg E, editor. Centrosomes in development and disease. Weinheim: Wiley-VCA; p. 353\u201370."},{"key":"3_CR129","first-page":"3867","volume":"29","author":"A Mukerjee","year":"2009","unstructured":"Mukerjee A, Viswanatha JK (2009). Formulation, characterization and evaluation of curcumin-loaded PLGA nanospheres for cancer therapy. Anticancer Res 29:3867\u20133876.","journal-title":"Anticancer Res"},{"key":"3_CR130","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1083\/jcb.141.3.663","volume":"141","author":"S Murphy","year":"1998","unstructured":"Murphy S, Urbani L, Stearns T (1998). The mammalian gamma-tubulin complex contains homologues of yeast spindle pole body component sspc97p and spc98p. J Cell Biol 141:663\u2013674.","journal-title":"J Cell Biol"},{"issue":"9","key":"3_CR131","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1039\/c2ib20088k","volume":"4","author":"GP Nagaraju","year":"2012","unstructured":"Nagaraju GP, Aliya S, Zafar SF, Basha R, Diazd R, El-Rayes BF (2012). The impact of curcumin on breast cancer. Integr Biol 4(9):996\u20131007. https:\/\/doi.org\/10.1039\/c2ib20088k.","journal-title":"Integr Biol"},{"key":"3_CR132","doi-asserted-by":"publisher","first-page":"22627","DOI":"10.1074\/jbc.C000235200","volume":"275","author":"R Ohki","year":"2000","unstructured":"Ohki R, Nemoto J, Murasawa H, Oda E, Inazawa J, Tanaka N, Taniguchi T (2000). Reprimo, a new candidate mediator of the p53-mediated cell cycle arrest at the G2 phase. J Biol Chem 275:22627\u201322630.","journal-title":"J Biol Chem"},{"key":"3_CR133","doi-asserted-by":"publisher","first-page":"5341","DOI":"10.1073\/pnas.87.14.5341","volume":"87","author":"Y Ohta","year":"1990","unstructured":"Ohta Y, Ohba T, Miyamoto E (1990). Ca2+\/calmodulin-dependent protein kinase II: localization in the interphase nucleus and the mitotic apparatus of mammalian cells. Proc Natl Acad Sci USA 87:5341\u20135345.","journal-title":"Proc Natl Acad Sci USA"},{"key":"3_CR134","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1083\/jcb.200108088","volume":"156","author":"T Ohta","year":"2002","unstructured":"Ohta T, Essner R, Ryu JH, Palazzo RE, Uetake Y, Kuriyama R (2002). Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells. J Cell Biol 156:87\u201399.","journal-title":"J Cell Biol"},{"key":"3_CR135","volume-title":"The centrosome, Chap 16","author":"OA Olivero","year":"2012","unstructured":"Olivero OA (2012). Centrosomal amplification and related abnormalities induced by nucleoside analogs. In: Schatten H, editor. The centrosome, Chap 16. New York: Springer Science and Business Media."},{"key":"3_CR136","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/S0074-7696(04)38003-4","volume":"238","author":"Y Ou","year":"2004","unstructured":"Ou Y, Rattner JB (2004). The centrosome in higher organisms: structure, composition and duplication. Int Rev Cytol 238:119\u2013182.","journal-title":"Int Rev Cytol"},{"key":"3_CR137","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1016\/j.cell.2007.06.018","volume":"129","author":"J Pan","year":"2007","unstructured":"Pan J, Snell W (2007). The primary cilium: keeper of the key to cell division. Cell 129: 1255\u20131257.","journal-title":"Cell"},{"key":"3_CR138","doi-asserted-by":"publisher","first-page":"9878","DOI":"10.1073\/pnas.0501821102","volume":"102","author":"D Panda","year":"2005","unstructured":"Panda D, Rathinasamy K, Santra MK, Wilson L (2005). Kinetic suppression of microtubule dynamic instability by griseofulvin: implications for its possible use in the treatment of cancer. Proc Natl Acad Sci USA 102:9878\u20139883.","journal-title":"Proc Natl Acad Sci USA"},{"key":"3_CR139","doi-asserted-by":"crossref","unstructured":"Patel N, Weekes D, Drosopoulos K, Gazinska P, Noel E, Rashid M, Mirza H, Quist J, Bras\u00f3-Maristany F, Mathew S, Ferro R, Pereira AM, Prince C, Noor F, Francesch-Domenech E, Marlow R, De Rinaldis E, Grigoriadis A, Linardopoulos S, Marra P, Tutt AN (2018). Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer. Nat Commun 9(1).","DOI":"10.1038\/s41467-018-03283-z"},{"key":"3_CR140","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1186\/1757-2215-7-53","volume":"7","author":"S Pawar","year":"2014","unstructured":"Pawar S, Donthamsetty S, Pannu V, et al (2014). KIFCI, a novel putative prognostic biomarker for ovarian adenocarcinomas: delineating protein interaction networks and signaling circuitries. J Ovarian Res 7:53","journal-title":"J Ovarian Res"},{"key":"3_CR141","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1006\/bcmd.1995.0006","volume":"21","author":"SF Pietromonaco","year":"1995","unstructured":"Pietromonaco SF, Seluja GA, Elias L (1995). Identification of enzymatically active Ca2+\/calmodulin dependent protein kinase in centrosomes of hematopoietic cells. Blood Cells Mol Dis 21:34\u201341.","journal-title":"Blood Cells Mol Dis"},{"key":"3_CR142","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1006\/scbi.1999.0131","volume":"9","author":"GA Pihan","year":"1999","unstructured":"Pihan GA, Doxsey SJ (1999). The mitotic machinery is a source of genetic instability in cancer. Semin Cancer Biol 9:289\u2013302.","journal-title":"Semin Cancer Biol"},{"key":"3_CR143","doi-asserted-by":"publisher","first-page":"3022","DOI":"10.1073\/pnas.94.7.3022","volume":"94","author":"SM Pockwinse","year":"1997","unstructured":"Pockwinse SM, Krockmalnic G, Doxsey SJ, Nickerson J, Lian JB, vanWijnen AJ, Stein JL, Stein GS, Penman S (1997). Cell cycle independent interaction of CDC with the centrosome, which is associated with the nuclear matrix-intermediate filament scaffold. Proc Natl Acad Sci USA 94:3022\u20133027.","journal-title":"Proc Natl Acad Sci USA"},{"key":"3_CR144","volume-title":"The centrosome, Chap 9","author":"SL Prosser","year":"2012","unstructured":"Prosser SL, Fry AM (2012). Regulation of the centrosome cycle by protein degradation. In: Schatten H, editor. The centrosome, Chap 9. New York: Springer Science and Business Media."},{"key":"3_CR145","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1016\/j.cell.2007.04.035","volume":"129","author":"EN Pugacheva","year":"2007","unstructured":"Pugacheva EN, Jablonski SA, Hartman TR, Henske EP, Golemis EA (2007). HEF1-dependent aurora A activation induces disassembly of the primary cilium. Cell 129:1351\u20131363.","journal-title":"Cell"},{"issue":"5","key":"3_CR146","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1083\/jcb.200503053","volume":"169","author":"LM Quarmby","year":"2005","unstructured":"Quarmby LM, Parker JDK (2005). Cilia and the cell cycle? J Cell Biol 169(5):707\u2013710.","journal-title":"J Cell Biol"},{"key":"3_CR147","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1083\/jcb.147.2.321","volume":"147","author":"NJ Quintyne","year":"1999","unstructured":"Quintyne NJ, Gill SR, Eckley DM, Crego CL, Compton DA, Schroer TA (1999). Dynactin is required for microtubule anchoring at fibroblast centrosomes. J Cell Biol 147:321\u2013334.","journal-title":"J Cell Biol"},{"key":"3_CR148","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1083\/jcb.200203089","volume":"159","author":"NJ Quintyne","year":"2002","unstructured":"Quintyne NJ, Schroer TA (2002). Distinct cell cycle-dependent roles for dynactin and dynein at centrosomes. J Cell Biol 159:245\u2013254.","journal-title":"J Cell Biol"},{"key":"3_CR149","doi-asserted-by":"publisher","unstructured":"Rao Z, Zhu Y, Yang P, Chen Z, Xia Y, Qiao C, Liu W, Deng H, Li J, Ning P, Wang Z (2022). Pyroptosis in inflammatory diseases and cancer. Theranostics 12(9):4310\u20134329. https:\/\/doi.org\/10.7150\/thno.71086. PMID: 35673561; PMCID: PMC9169370.","DOI":"10.7150\/thno.71086"},{"key":"3_CR150","doi-asserted-by":"publisher","unstructured":"Reader JC, Fan C, Ory EC, Ju J, Lee R, Vitolo MI, Smith P, Wu S, Ching MMN, Asiedu EB, Jewell CM, Rao GG, Fulton A, Webb TJ, Yang P, Santin AD, Huang HC, Martin SS, Roque DM (2022). Microtentacle formation in ovarian carcinoma. Cancers (Basel) 14(3):800. https:\/\/doi.org\/10.3390\/cancers14030800. PMID: 35159067; PMCID: PMC8834106.","DOI":"10.3390\/cancers14030800"},{"key":"3_CR151","doi-asserted-by":"publisher","first-page":"6342","DOI":"10.1158\/0008-5472.CAN-07-0663","volume":"67","author":"B Rebacz","year":"2007","unstructured":"Rebacz B, Larsen TO Clausen MH, Ronnest MH, Loffler H, Ho AD, Kr\u00e4mer A (2007). Identification of griseofulvin as an inhibitor of centrosomal clustering in a phenotype-based screen. Cancer Res 67:6342\u201350.","journal-title":"Cancer Res"},{"key":"3_CR152","doi-asserted-by":"publisher","first-page":"5136","DOI":"10.1158\/1078-0432.CCR-05-1650","volume":"12","author":"R Reiter","year":"2006","unstructured":"Reiter R, Gais P, Jutting U, Steuer-Vogt MK, Pickhard A, Bink K, Rauser S, Lassmann S, H\u00f6fler H, Werner M, Walch A (2006). Aurora kinase A messenger RNA overexpression is correlated with tumor progression and shortened survival in head and neck squamous cell carcinoma. Clin Cancer Res 12:5136\u20135141.","journal-title":"Clin Cancer Res"},{"key":"3_CR153","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1007\/s12263-011-0222-1","volume":"6","author":"S Reuter","year":"2011","unstructured":"Reuter S, Gupta SC, Park B, Goel A, Aggarwal BB (2011). Epigenetic changes induced by curcumin and other natural compounds. Genes Nutr 6:93\u2013108.","journal-title":"Genes Nutr"},{"key":"3_CR154","doi-asserted-by":"publisher","unstructured":"Rosen DG, Yang G, Liu G, Mercado-Uribe I, Chang B, Xiao XS, Zheng J, Xue FX, Liu J (2009). Ovarian cancer: pathology, biology, and disease models. Front Biosci (Landmark Ed) 14(6):2089\u2013102. https:\/\/doi.org\/10.2741\/3364. PMID: 19273186; PMCID: PMC2858969.","DOI":"10.2741\/3364"},{"key":"3_CR155","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1007\/s00418-007-0366-7","volume":"129","author":"J Roth","year":"2008","unstructured":"Roth J, Yam GH, Fan J, Hirano K, Gaplovska-Kysela K, Le Fourn V, Guhl B, Santimaria R, Torossi T, Ziak M, Zuber C (2008). Protein quality control: the who\u2019s who, the where\u2019s and therapeutic escapes. Histochem Cell Biol 129:163\u2013177.","journal-title":"Histochem Cell Biol"},{"key":"3_CR156","doi-asserted-by":"publisher","first-page":"6284","DOI":"10.1021\/jm700988f","volume":"50","author":"A Safavy","year":"2007","unstructured":"Safavy A, Raisch PKP, Mantena S, Sanford LL, Sham SW, Krishna NR, Bonner JA (2007). Design and development of water-soluble curcumin conjugates as potential anticancer agents. J Med Chem 50:6284\u20136288.","journal-title":"J Med Chem"},{"key":"3_CR157","volume-title":"The centrosome, Chap 13","author":"C Saladino","year":"2012","unstructured":"Saladino C, Bourke E, Morrison CG (2012). Centrosomes, DNA damage and aneuploidy. In: Schatten H, editor. The centrosome, Chap 13. New York: Springer Science and Business Media."},{"key":"3_CR158","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/0955-0674(95)80043-3","volume":"7","author":"JL Salisbury","year":"1995","unstructured":"Salisbury JL (1995). Centrin, centrosomes, and mitotic spindle poles. Curr Opin Cell Biol 7:39\u201345.","journal-title":"Curr Opin Cell Biol"},{"key":"3_CR159","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1016\/S0960-9822(02)01019-9","volume":"12","author":"JL Salisbury","year":"2002","unstructured":"Salisbury JL, Suino KM, Busby R, Springett M (2002). Centrin-2 is required for centriole duplication in mammalian cells. Curr Biol 12:1287\u20131292.","journal-title":"Curr Biol"},{"key":"3_CR160","doi-asserted-by":"publisher","first-page":"R27","DOI":"10.1016\/j.cub.2003.12.019","volume":"14","author":"JL Salisbury","year":"2004","unstructured":"Salisbury JL (2004). Centrosomes: Sfi1p and centrin unravel a structural riddle. Curr Biol 14:R27\u201329.","journal-title":"Curr Biol"},{"key":"3_CR161","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1242\/jcs.110.11.1287","volume":"110","author":"A Saredi","year":"1997","unstructured":"Saredi A, Howard L, Compton DA (1997). Phosphorylation regulates the assembly of NuMA in a mammalian mitotic extract. J Cell Sci 110:1287\u20131297.","journal-title":"J Cell Sci"},{"key":"3_CR162","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1007\/s00418-008-0416-9","volume":"129","author":"P Satir","year":"2008","unstructured":"Satir P, Christensen ST (2008). Structure and function of mammalian cilia. Histochem Cell Biol 129:687\u2013693.","journal-title":"Histochem Cell Biol"},{"key":"3_CR163","first-page":"4158","volume":"63","author":"N Sato","year":"2003","unstructured":"Sato N, Maitra A, Fukushima N, van Heek NT, Matsubayashi H, Iacobuzio-Donahue CA, Rosty C, Goggins M (2003). Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma. Cancer Res 63:4158\u201366.","journal-title":"Cancer Res"},{"key":"3_CR164","doi-asserted-by":"publisher","unstructured":"Sauer et al (2022). Molecular landscape and functional characterization of centrosome amplification in ovarian cancer. https:\/\/doi.org\/10.1101\/2022.09.13.507750","DOI":"10.1101\/2022.09.13.507750"},{"key":"3_CR165","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1083\/jcb.94.2.455","volume":"94","author":"G Schatten","year":"1982","unstructured":"Schatten G, Schatten H, Bestor T, Balczon R (1982a). Taxol inhibits the nuclear movements during fertilization and induces asters in unfertilized sea urchin eggs. J Cell Biol 94:455\u2013465.","journal-title":"J Cell Biol"},{"key":"3_CR166","unstructured":"Schatten H (1977). Untersuchungen \u00fcber die Wirkung von Griseofulvin in Seeigeleiern und in Mammalierzellen. Universit\u00e4t Heidelberg; 1977 (Effects of griseofulvin on sea urchin eggs and on mammalian cells. University of Heidelberg; 1977)."},{"key":"3_CR167","first-page":"74","volume":"27","author":"H Schatten","year":"1982","unstructured":"Schatten H, Schatten G, Petzelt C, Mazia D (1982b). Effects of griseofulvin on fertilization and early development of sea urchins. Independence of DNA synthesis, chromosome condensation, and cytokinesis cycles from microtubule-mediated events. Eur J Cell Biol 27:74\u201387.","journal-title":"Eur J Cell Biol"},{"key":"3_CR168","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/S0248-4900(00)01079-0","volume":"92","author":"H Schatten","year":"2000","unstructured":"Schatten H, Wiedemeier A, Taylor M, Lubahn D, Greenberg NM, Besch-Williford C, Rosenfeld C, Day K, Ripple M (2000). Centrosomes-centriole abnormalities are markers for abnormal cell divisions and cancer in the transgenic adenocarcinoma mouse prostate (TRAMP) model. Biol Cell 92:331\u2013340.","journal-title":"Biol Cell"},{"key":"3_CR169","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1007\/s00418-008-0427-6","volume":"129","author":"H Schatten","year":"2008","unstructured":"Schatten H (2008). The mammalian centrosome and its functional significance. Histochem Cell Biol 129:667\u2013686.","journal-title":"Histochem Cell Biol"},{"issue":"8","key":"3_CR170","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1002\/em.20493","volume":"50","author":"H Schatten","year":"2009","unstructured":"Schatten H, Sun QY (2009). The functional significance of centrosomes in mammalian meiosis, fertilization, development, nuclear transfer, and stem cell differentiation. Environ Mol Mutagen 50(8):620\u2013636.","journal-title":"Environ Mol Mutagen"},{"key":"3_CR171","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1016\/j.semcdb.2010.01.012","volume":"21","author":"H Schatten","year":"2010","unstructured":"Schatten H, Sun Q-Y (2010). The role of centrosomes in fertilization, cell division and establishment of asymmetry during embryo development. Semin Cell Dev Biol 21:174\u2013184.","journal-title":"Semin Cell Dev Biol"},{"key":"3_CR090","doi-asserted-by":"crossref","unstructured":"Schatten H, Sun Q-Y (2011) The significant role of centrosomes in stem cell division and differentiation. Microsc Microanal 17(4):506\u2013512.","DOI":"10.1017\/S1431927611000018"},{"key":"3_CR01","doi-asserted-by":"crossref","unstructured":"Schatten, H. (2013). The impact of centrosome abnormalities on breast cancer development and progression with a focus on targeting centrosomes for Breast Cancer Therapy. In: Cell and Molecular Biology of Breast Cancer. Edited by Heide Schatten, published by Springer Science and Business Media, LLC.","DOI":"10.1007\/978-1-62703-634-4_12"},{"key":"3_CR02","doi-asserted-by":"crossref","unstructured":"Schatten, H. (2014). The role of centrosomes in cancer stem cell functions. Chapter 12, pages 259\u2013279. In: Cell and Molecular Biology and Imaging of Stem Cells, First Edition. Edited by Heide Schatten. \u00a9 2014 John Wiley & Sons, Inc. Published 2014 by John Wiley & Sons, Inc.","DOI":"10.1002\/9781118285602.ch12"},{"key":"3_CR172","doi-asserted-by":"publisher","unstructured":"Schatten H, Sun QY. (2014). Posttranslationally modified tubulins and other cytoskeletal proteins: their role in gametogenesis, oocyte maturation, fertilization and Pre-implantation embryo development. Adv Exp Med Biol. 2014;759:57\u201387. https:\/\/doi.org\/10.1007\/978-1-4939-0817-2_(Invited book chapter: In Posttranslational Protein Modifications in the Reproductive System; Edited by Peter Sutovsky; Springer Science and Business Media)","DOI":"10.1007\/978-1-4939-0817-2"},{"key":"3_CR173","doi-asserted-by":"publisher","unstructured":"Schatten H, Sun QY (2018). Functions and dysfunctions of the mammalian centrosome in health, disorders, disease, and aging. Histochem Cell Biol 150(4):303\u2013325. https:\/\/doi.org\/10.1007\/s00418-018-1698-1. PMID: 30062583.","DOI":"10.1007\/s00418-018-1698-1"},{"key":"3_CR174","doi-asserted-by":"publisher","unstructured":"Schatten H (2022a). Centrosome Dysfunctions in Cancer. Adv Anat Embryol Cell Biol 235:43\u201350. https:\/\/doi.org\/10.1007\/978-3-031-20848-5_4. PMID: 36525110","DOI":"10.1007\/978-3-031-20848-5_4"},{"key":"3_CR175","doi-asserted-by":"publisher","unstructured":"Schatten H (2022b). The Centrosome Cycle within the Cell Cycle. Adv Anat Embryol Cell Biol 235:17\u201335. https:\/\/doi.org\/10.1007\/978-3-031-20848-5_2. PMID: 36525108","DOI":"10.1007\/978-3-031-20848-5_2"},{"key":"3_CR176","doi-asserted-by":"publisher","first-page":"20130469","DOI":"10.1098\/rstb.2013.0469","volume":"369","author":"U Scheer","year":"2014","unstructured":"Scheer U (2014). Historical roots of centrosome research: discovery of Boveri's microscope slides in W\u00fcrzburg. Philos. Trans. R. Soc. B 369, 20130469. https:\/\/doi.org\/10.1098\/rstb.2013.0469","journal-title":"Philos. Trans. R. Soc. B"},{"key":"3_CR177","doi-asserted-by":"publisher","unstructured":"Scheer U (2018). Boveri\u2019s research at the Zoological Station Naples: Rediscovery of his original microscope slides at the University of W\u00fcrzburg. Marine Genomics https:\/\/doi.org\/10.1016\/j.margen.2018.01.003","DOI":"10.1016\/j.margen.2018.01.003"},{"key":"3_CR178","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1038\/277665a0","volume":"277","author":"PB Schiff","year":"1979","unstructured":"Schiff PB, Fant J, Horwitz SB (1979). Promotion of microtubule assembly in vitro by taxol. Nature 277:665\u2013667.","journal-title":"Nature"},{"key":"3_CR179","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1038\/sj.onc.1206195","volume":"22","author":"BP Schlegel","year":"2003","unstructured":"Schlegel BP, Starita LM, Parvin JD (2003). Overexpression of a protein fragment of RNA helicase A causes inhibition of endogenous BRCA1 function and defects in ploidy and cytokinesis in mammary epithelial cells. Oncogene 22:983\u2013991.","journal-title":"Oncogene"},{"key":"3_CR180","doi-asserted-by":"publisher","first-page":"1861","DOI":"10.1016\/j.cub.2005.09.012","volume":"15","author":"L Schneider","year":"2005","unstructured":"Schneider L, Clement CA, Teilmann SC, et al (2005). PDGFR alpha signaling is regulated through the primary cilium in fibroblasts. Curr Biol 15:1861\u20131866.","journal-title":"Curr Biol"},{"key":"3_CR181","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1016\/S0955-0674(00)00179-4","volume":"13","author":"TA Schroer","year":"2001","unstructured":"Schroer TA (2001). Microtubules don and doff their caps: dynamic attachments at plus and minus ends. Curr Opin Cell Biol 13:92\u201396.","journal-title":"Curr Opin Cell Biol"},{"key":"3_CR182","doi-asserted-by":"publisher","first-page":"2461","DOI":"10.1158\/1535-7163.MCT-08-0857","volume":"8","author":"X Shang","year":"2009","unstructured":"Shang X, Burlingame SM, Okcu MF, Ge N, Russell HV, Egler RA, David RD, Vasudevan SA, Yang J, Nuchtern JG (2009). Aurora A is a negative prognostic factor and a new therapeutic target in human neuroblastoma. Mol Cancer Ther 8:2461\u20132469.","journal-title":"Mol Cancer Ther"},{"key":"3_CR183","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1172\/JCI39447","volume":"120","author":"S Shao","year":"2010","unstructured":"Shao S, Liu R, Wang Y, et al (2010). Centrosomal Nlp is an oncogenic protein that is gene-amplified in human tumors and causes spontaneous tumorigenesis in transgenic mice. J Clin Invest 120:498\u2013507.","journal-title":"J Clin Invest"},{"issue":"85","key":"3_CR184","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1016\/S0070-2153(08)00813-2","volume":"2008","author":"N Sharma","year":"2008","unstructured":"Sharma N, Berbari NF, Yoder BK (2008). Ciliary dysfunction in developmental abnormalities and diseases. Curr Top Dev Biol 2008(85):371\u2013427.","journal-title":"Curr Top Dev Biol"},{"issue":"1","key":"3_CR185","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1039\/C2IB20047C","volume":"5","author":"SJ Shin","year":"2012","unstructured":"Shin SJ, Beech JR, Kelly KA (2012). Targeted nanoparticles in imaging: paving the way for personalized medicine in the battle against cancer. Integr Biol 5(1):29\u201342. https:\/\/doi.org\/10.1039\/C2IB20047C.","journal-title":"Integr Biol"},{"key":"3_CR186","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1021\/acsmedchemlett.9b00526","volume":"11","author":"K Shintani","year":"2020","unstructured":"Shintani K, Ebisu H, Mukaiyama M, Hatanaka T, Chinen T, Takao D, Nagumo Y, Sakakura A, Hayakawa I, Usui, T (2020). Structure optimization of gatastatin for the development of \u03b3-tubulin-specific inhibitor. ACS Med Chem Lett 11:1125\u20131129.","journal-title":"ACS Med Chem Lett"},{"key":"3_CR187","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1002\/3527603808.ch9","volume-title":"Centrosomes in development and disease","author":"G Sluder","year":"2004","unstructured":"Sluder G (2004). Centrosome duplication and its regulation in the higher animal cell. In: Nigg E, editor. Centrosomes in development and disease. Weinheim: Wiley-VCA; p. 167\u201389."},{"key":"3_CR188","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1083\/jcb.15.2.363","volume":"15","author":"S Sorokin","year":"1962","unstructured":"Sorokin S (1962). Centrioles and the formation of rudimentary cilia by fibroblasts and smooth muscle cells. J Cell Biol 15:363\u2013377.","journal-title":"J Cell Biol"},{"key":"3_CR189","doi-asserted-by":"publisher","first-page":"8457","DOI":"10.1128\/MCB.24.19.8457-8466.2004","volume":"24","author":"LM Starita","year":"2004","unstructured":"Starita LM, Machida Y, Sankaran S, Elias JE, Griffin K, Schlegel BP, Gygi SP, Parvin JD (2004). BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number. Mol Cell Biol 24:8457\u20138466.","journal-title":"Mol Cell Biol"},{"issue":"33","key":"3_CR190","doi-asserted-by":"publisher","first-page":"30165","DOI":"10.1074\/jbc.M201914200","volume":"277","author":"BT Steadman","year":"2002","unstructured":"Steadman BT, Schmidt PH, Shanks RA, Lapierre LA, Goldenring JR (2002). Transforming acidic coiled-coil-containing protein 4 interacts with centrosomal AKAP350 and the mitotic spindle apparatus. J Biol Chem 277(33):30165\u201330176.","journal-title":"J Biol Chem"},{"key":"3_CR191","doi-asserted-by":"crossref","unstructured":"Steiert B, Icardi CM, Faris R, Weber MM (2023). The Chlamydia trachomatis type III-secreted effector protein CteG induces centrosome amplification through interactions with centrin-2. PNAS Vol. 120 No. 20, e2303487120, 1\u201311.","DOI":"10.1073\/pnas.2303487120"},{"key":"3_CR192","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1095\/biolreprod64.3.879","volume":"64","author":"QY Sun","year":"2001","unstructured":"Sun QY, Lai L, Park KW, K\u00fchholzer B, Prather RS, Schatten H (2001a). Dynamic events are differently regulated by microfilaments, microtubules, and mitogen-activated protein kinase during porcine oocyte maturation and fertilization in vitro. Biol Reprod 64:879\u2013889.","journal-title":"Biol Reprod"},{"key":"3_CR193","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1002\/mrd.1022","volume":"59","author":"QY Sun","year":"2001","unstructured":"Sun QY, Lai L, Bonk A, Prather RS, Schatten H (2001b). Cytoplasmic changes in relation to nuclear maturation and early embryo developmental potential of porcine oocytes: effects of gonadotropins, cumulus cells, follicular size and protein synthesis inhibition. Mol Reprod Dev 59:192\u2013198.","journal-title":"Mol Reprod Dev"},{"key":"3_CR194","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1002\/mrd.1113","volume":"60","author":"Q-Y Sun","year":"2001","unstructured":"Sun Q-Y, Lai L, Wu G, Park K-W, Day B, Prather RS, Schatten H (2001c). Microtubule assembly after treatment of pig oocytes with taxol: correlation with chromosomes, \u03b3-tubulin and MAP kinase. Mol Reprod Dev 60:481\u2013490.","journal-title":"Mol Reprod Dev"},{"key":"3_CR195","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1530\/rep.0.1220155","volume":"122","author":"Q-Y Sun","year":"2001","unstructured":"Sun Q-Y, Wu GM, Lai L, Park KW, Day B, Prather RS, Schatten H (2001d). Translocation of active mitochondria during porcine oocyte maturation, fertilization and early embryo development in vitro. Reproduction 122:155\u2013163.","journal-title":"Reproduction"},{"issue":"3","key":"3_CR196","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1095\/biolreprod66.3.580","volume":"66","author":"Q-Y Sun","year":"2002","unstructured":"Sun Q-Y, Lai L, Wu G, Bonk A, Cabot R, Park K-W, Day B, Prather RS, Schatten H (2002). Regulation of mitogen-activated protein kinase phosphorylation, microtubule organization, chromatin behavior, and cell cycle progression are regulated by protein phosphatases during pig oocyte maturation and fertilization in vitro. Biol Reprod 66(3):580\u2013588.","journal-title":"Biol Reprod"},{"key":"3_CR197","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.2741\/1868","volume":"11","author":"QY Sun","year":"2006","unstructured":"Sun QY, Schatten H (2006). Multiple roles of NuMA in vertebrate cells: Review of an intriguing multi-functional protein. Front Biosci 11:1137\u20131146.","journal-title":"Front Biosci"},{"key":"3_CR198","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1007\/978-0-387-37754-4_4","volume":"591","author":"Q-Y Sun","year":"2007","unstructured":"Sun Q-Y, Schatten H (2007). Centrosome inheritance after fertilization and nuclear transfer in mammals. In: Sutovsky P (ed) Somatic cell nuclear transfer. Landes Bioscience. Adv Exp Med Biol 591:58\u201371.","journal-title":"Adv Exp Med Biol"},{"key":"3_CR199","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1016\/j.otohns.2008.12.049","volume":"140","author":"MI Syed","year":"2009","unstructured":"Syed MI, Syed S, Minty F, Harrower S, Singh J, Chin A, McLellan DR, Parkinson EK, Clark LJ (2009). Gamma tubulin: A promising indicator of recurrence in squamous cell carcinoma of the larynx. Otolaryngol Head Neck Surg 140:498\u2013504.","journal-title":"Otolaryngol Head Neck Surg"},{"key":"3_CR200","doi-asserted-by":"publisher","first-page":"3235","DOI":"10.1091\/mbc.e02-02-0112","volume":"13","author":"M Takahashi","year":"2002","unstructured":"Takahashi M, Yamagiwa A, Nishimura T, Mukai H, Ono Y (2002). Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex. Mol Biol Cell 13:3235\u20133245.","journal-title":"Mol Biol Cell"},{"key":"3_CR201","first-page":"1833","volume":"6","author":"MM Tanner","year":"2000","unstructured":"Tanner MM, Grenman S, Koul A, Johannsson O, Meltzer P, Pejovic T, Borg A, Isola JJ (2000). Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer. Clin Cancer Res 6:1833\u20131839.","journal-title":"Clin Cancer Res"},{"key":"3_CR202","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1083\/jcb.141.3.689","volume":"141","author":"AM Tassin","year":"1998","unstructured":"Tassin AM, Celati C, Moudjou M, Bornens M (1998). Characterization of the human homologue of the yeast Spc98p and its association with gamma-tubulin. J Cell Biol 141:689\u2013701.","journal-title":"J Cell Biol"},{"key":"3_CR203","first-page":"4445","volume":"125","author":"N Teixid\u00f3-Travesa","year":"2012","unstructured":"Teixid\u00f3-Travesa N, Roig J, L\u00fcders J (2012). The where, when and how of microtubule nucleation\u2014one ring to rule them all. J Cell Sci 125:4445\u20134456.","journal-title":"J Cell Sci"},{"key":"3_CR204","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1095\/biolreprod67.2.546","volume":"67","author":"C Tong","year":"2002","unstructured":"Tong C, Fan H-Y, Lian L, Li S-W, Chen D-Y, Schatten H, Sun Q-Y (2002). Polo-like kinase-1 is a pivotal regulator of microtubule assembly during mouse oocyte meiotic maturation, fertiliza tion, and early embryonic mitosis. Biol Reprod 67:546\u2013554.","journal-title":"Biol Reprod"},{"issue":"5","key":"3_CR205","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1038\/sj.cr.7290183","volume":"13","author":"C Tong","year":"2003","unstructured":"Tong C, Fan H-Y, Li S-W, Chen D-Y, Song X-F, Schatten H, Sun Q-Y (2003). Effects of MEK inhibitor U0126 on meiotic progression in mouse oocytes: microtubule organization, asymmetric division and metaphase II arrest. Cell Res 13(5):375\u2013383.","journal-title":"Cell Res"},{"key":"3_CR206","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/S0378-5173(02)00323-X","volume":"244","author":"HH Tonnesen","year":"2002","unstructured":"Tonnesen HH, Masson M, Loftsson T (2002). Studies of curcumin and curcuminoids. XXVII. Cyclodextrin complexation: solubility, chemical and photochemical stability. Int J Pharm 244:127\u2013135.","journal-title":"Int J Pharm"},{"key":"3_CR207","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1016\/0092-8674(95)90336-4","volume":"81","author":"S Tugendreich","year":"1995","unstructured":"Tugendreich S, Tomkiel J, Earnshaw W, Hieter P (1995). CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition. Cell 81:261\u2013268.","journal-title":"Cell"},{"key":"3_CR208","doi-asserted-by":"publisher","unstructured":"Tymon-Rosario J, Adjei NN, Roque DM, Santin AD (2021). Microtubule-interfering drugs: current and future roles in epithelial ovarian cancer treatment. Cancers (Basel) 13(24):6239. https:\/\/doi.org\/10.3390\/cancers13246239. PMID: 34944858; PMCID: PMC8699494.","DOI":"10.3390\/cancers13246239"},{"issue":"5","key":"3_CR209","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1002\/jcb.21240","volume":"101","author":"YH Uen","year":"2007","unstructured":"Uen YH, Liu DZ, Weng MS, Ho YS, Lin SY (2007). NF-kappa B pathway is involved in griseofulvin-induced G2\/M arrest and apoptosis in HL-60 cells. J Cell Biochem 101(5):1165\u20131175.","journal-title":"J Cell Biochem"},{"key":"3_CR210","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1159\/000208212","volume":"111","author":"IR Veland","year":"2009","unstructured":"Veland IR, Awan A, Pedersen LB, Yoder BK, Christensen ST (2009). Primary cilia and signaling pathways in mammalian development, health and disease. Nephron Physiol 111:39\u201353.","journal-title":"Nephron Physiol"},{"key":"3_CR211","doi-asserted-by":"publisher","first-page":"1367","DOI":"10.1016\/S0960-9822(00)00776-4","volume":"10","author":"J Wakefield","year":"2000","unstructured":"Wakefield J, Huang J-Y, Raff JW (2000). Centrosomes have a role in regulating the destruction of cyclin B in early Drosophila embryos. Curr Biol 10:1367\u20131370.","journal-title":"Curr Biol"},{"issue":"10","key":"3_CR212","doi-asserted-by":"publisher","first-page":"3450","DOI":"10.1128\/MCB.22.10.3450-3459.2002","volume":"22","author":"Q Wang","year":"2002","unstructured":"Wang Q, Xie S, Chen J, Fukasawa K, Naik U, Traganos F, Darzynkiewicz Z, Jhanwar-Uniyal M, Dai W (2002). Cell cycle arrest and apoptosis by human polo-like kinase 3 is mediated through perturbation of microtubule integrity. Mol Cell Biol 22(10):3450\u20133459.","journal-title":"Mol Cell Biol"},{"key":"3_CR213","doi-asserted-by":"publisher","first-page":"7148","DOI":"10.1038\/sj.onc.1209707","volume":"25","author":"X Wang","year":"2006","unstructured":"Wang X, Zhou YX, Qiao W, et al (2006). Overexpression of aurora kinase A in mouse mammary epithelium induces genetic instability preceding mammary tumor formation. Oncogene 25:7148\u20137158.","journal-title":"Oncogene"},{"key":"3_CR214","doi-asserted-by":"publisher","first-page":"6228","DOI":"10.1158\/1078-0432.CCR-07-5177","volume":"14","author":"D Wang","year":"2008","unstructured":"Wang D, Veena MS, Stevenson K, Tang C, Ho B, Suh JD, Duarte V, Faull KF, Mehta K, Srivatsan ES, Wang MB (2008). Liposome-encapsulated curcumin suppresses growth of head and neck squamous cell carcinoma in vitro and in xenografts through the inhibition of nuclear factor kappa B by an AKT-independent pathway. Clin Cancer Res 14:6228\u20136236.","journal-title":"Clin Cancer Res"},{"key":"3_CR215","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1158\/0008-5472.CAN-10-0030","volume":"71","author":"HF Wang","year":"2011","unstructured":"Wang HF, Takenaka K, Nakanishi A, et al (2011). BRCA2 and nucleophosmin coregulate centro some amplification and form a complex with the Rho effector kinase ROCK2. Cancer Res 71:68\u201377.","journal-title":"Cancer Res"},{"key":"3_CR216","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/S0022-2836(77)80055-7","volume":"111","author":"J Wehland","year":"1977","unstructured":"Wehland J, Herzog W, Weber K (1977). Interaction of griseofulvin with microtubules, microtubule protein and tubulin. J Mol Biol 111:329\u2013342.","journal-title":"J Mol Biol"},{"issue":"6","key":"3_CR217","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0021557","volume":"6","author":"Y Wei","year":"2011","unstructured":"Wei Y, Multi S, Yang CR, Ma J, Zhang QH, Wang ZB, Li M, Wei L, Ge ZJ, Zhang CH, Ouyang YC, Hou Y, Schatten H, Sun QY (2011). Spindle assembly checkpoint regulates mitotic cell cycle progression during preimplantation embryo development. PLoS One 6(6):e21557","journal-title":"PLoS One"},{"key":"3_CR218","doi-asserted-by":"publisher","unstructured":"Wen S, Liu Y, Yang M, Yang K, Huang J, Feng D (2016). Increased NEK2 in hepatocellular carcinoma promotes cancer progression and drug resistance by promoting PP1\/Akt and Wnt activation. Oncol Rep 36:2193\u20132199. PMID: 27509921. https:\/\/doi.org\/10.3892\/or.2016.5009","DOI":"10.3892\/or.2016.5009"},{"key":"3_CR219","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1006\/cbir.1996.0011","volume":"20","author":"DN Wheatley","year":"1996","unstructured":"Wheatley DN, Wang AM, Strugnell GE (1996). Expression of primary cilia in mammalian cells. Cell Biol Int 20:73\u201381.","journal-title":"Cell Biol Int"},{"issue":"12","key":"3_CR220","first-page":"1","volume":"10","author":"R Wilken","year":"2011","unstructured":"Wilken R, Veena MS, Wang MB, Srivatsan ES (2011). Curcumin: a review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma. Mol Cancer 10(12):1\u201319.","journal-title":"Mol Cancer"},{"key":"3_CR221","first-page":"125","volume-title":"Centrosomes in development and disease","author":"CJ Wilkinson","year":"2004","unstructured":"Wilkinson CJ, Andersen JS, Mann M, Nigg EA (2004). A proteomic approach to the inventory of the human centrosome. In: Nigg E, editor. Centrosomes in development and disease. Weinheim: Wiley-VCA; p. 125\u201342."},{"key":"3_CR222","doi-asserted-by":"publisher","first-page":"20130459","DOI":"10.1098\/rstb.2013.0459","volume":"369","author":"JB Woodruff","year":"2014","unstructured":"Woodruff JB, Wueseke O, Hyman AA (2014). Pericentriolar material structure and dynamics. Philos Trans R Soc Lond B Biol Sci 369, 20130459.","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"3_CR223","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1016\/S1357-2725(02)00380-1","volume":"35","author":"C Wojcik","year":"2003","unstructured":"Wojcik C, DeMartino GN (2003). Intracellular localization of proteasomes. Int J Biochem Cell Biol 35:579\u2013589.","journal-title":"Int J Biochem Cell Biol"},{"key":"3_CR224","doi-asserted-by":"publisher","unstructured":"Xia J, Franqui Machin R, Gu Z, Zhan F (2015). Role of NEK2A in human cancer and its therapeutic potentials. Biomed Res Int:862461. PMID: 4330945. https:\/\/doi.org\/10.1155\/2015\/862461","DOI":"10.1155\/2015\/862461"},{"key":"3_CR225","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1016\/S1097-2765(00)80466-9","volume":"3","author":"X Xu","year":"1999","unstructured":"Xu X, Weaver Z, Linke SP, Li C, Gotay J, Wang XW, Harris CC, Ried T, Deng CX (1999). Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic insta bility in BRCA1 exon 11 isoform-deficient cells. Mol Cell 3:389\u2013395.","journal-title":"Mol Cell"},{"issue":"1","key":"3_CR226","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.jcis.2010.05.022","volume":"351","author":"MM Yallapu","year":"2010","unstructured":"Yallapu MM, Gupta BK, Jaggi M, Chauhan SC (2010a). Fabrication of curcumin encapsulated PLGA nanoparticles for improved therapeutic effects in metastatic cancer cells. J Colloid Interface Sci 351(1):19\u201329.","journal-title":"J Colloid Interface Sci"},{"key":"3_CR227","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1002\/mabi.201000084","volume":"10","author":"MM Yallapu","year":"2010","unstructured":"Yallapu MM, Jaggi M, Chauhan SC (2010b). Poly(\u03b2-cyclodextrin)\/curcumin self-assembly: a novel approach to improve curcumin delivery and its therapeutic efficacy in prostate cancer cells. Macromol Biosci 10:1141\u20131151.","journal-title":"Macromol Biosci"},{"key":"3_CR228","first-page":"209","volume":"18","author":"HF Yam","year":"1998","unstructured":"Yam HF, Wang ZH, Or PC, Wang SW, Li J, Chew EC(1998). Effect of glucocorticoid hormone on nuclear matrix in cervical cancer cells in vitro. Anticancer Res 18:209\u2013216.","journal-title":"Anticancer Res"},{"issue":"8","key":"3_CR229","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1039\/c2ib20045g","volume":"4","author":"M Yamaguchi","year":"2012","unstructured":"Yamaguchi M, Moore TW, Sun A, Snyder JP, Shoji M (2012). Novel curcumin analogue UBS109 potently stimulates osteoblastogenesis and suppresses osteoclastogenesis through Smad activation and NF\u03baB inhibition. Integr Biol 4(8):905\u2013913.","journal-title":"Integr Biol"},{"key":"3_CR230","volume-title":"The centrosome, Chap 15","author":"B Yan","year":"2012","unstructured":"Yan B, Chng W-J (2012). The role of centrosomes in multiple myeloma. In: Schatten H, editor. The centrosome, Chap 15. New York: Springer Science and Business Media."},{"key":"3_CR231","doi-asserted-by":"crossref","unstructured":"Yang Y, Zhou W, Xia J, Gu Z, Wendlandt E, Zhan X, Janz S, Tricot G, Zhan F (2014). NEK2 mediates ALDH1A1-dependent drug resistance in multiple myeloma. Oncotarget 5:11986\u201311997. PMID: 4322982.","DOI":"10.18632\/oncotarget.2388"},{"key":"3_CR233","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1158\/1535-7163.MCT-09-0674","volume":"9","author":"S Yin","year":"2010","unstructured":"Yin S, Bhattacharya R, Cabral F (2010). Human mutations that confer paclitaxel resistance. Mol Cancer Ther 9:327\u2013335.","journal-title":"Mol Cancer Ther"},{"issue":"8","key":"3_CR234","doi-asserted-by":"publisher","first-page":"3167","DOI":"10.1021\/jf0632379","volume":"55","author":"H Yoon","year":"2007","unstructured":"Yoon H, Liu RH (2007). Effect of selected phytochemicals and apple extracts on NF\u2013kB activation in human breast cancer MCF-7 cells. J Agric Food Chem 55(8):3167\u20133173.","journal-title":"J Agric Food Chem"},{"key":"3_CR235","doi-asserted-by":"publisher","first-page":"2047","DOI":"10.1091\/mbc.11.6.2047","volume":"11","author":"A Young","year":"2000","unstructured":"Young A, Dictenberg JB, Purohit A, Tuft R, Doxsey SJ (2000). Cytoplasmic dynein-mediated assembly of pericentrin and \u03b3 tubulin onto centrosomes. Mol Biol Cell 11:2047\u20132056.","journal-title":"Mol Biol Cell"},{"key":"3_CR236","doi-asserted-by":"publisher","unstructured":"Zhou W, Yang Y, Xia J, Wang H, Salama ME, Xiong W, Xu H, Shetty S, Chen T, Zeng Z, Shi L, Zangari M, Miles R, Bearss D, Tricot G, Zhan F (2013). NEK2 induces drug resistance mainly through activation of efflux drug pumps and is associated with poor prognosis in myeloma and other cancers. Cancer Cell 23:48\u201362. PMID: 23328480. https:\/\/doi.org\/10.1016\/j.ccr.2012.12.001","DOI":"10.1016\/j.ccr.2012.12.001"}],"container-title":["Advances in Experimental Medicine and Biology","Cell and Molecular Biology of Ovarian Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-031-58311-7_3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T07:01:59Z","timestamp":1716879719000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-031-58311-7_3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"ISBN":["9783031583100","9783031583117"],"references-count":238,"URL":"https:\/\/doi.org\/10.1007\/978-3-031-58311-7_3","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]},"assertion":[{"value":"29 May 2024","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}