{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T20:57:45Z","timestamp":1743022665334,"version":"3.40.3"},"publisher-location":"Cham","reference-count":82,"publisher":"Springer International Publishing","isbn-type":[{"type":"print","value":"9783031583100"},{"type":"electronic","value":"9783031583117"}],"license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024]]},"DOI":"10.1007\/978-3-031-58311-7_5","type":"book-chapter","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T11:01:21Z","timestamp":1716894081000},"page":"97-105","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Role of the Human Microbiome in Epithelial Ovarian Cancer"],"prefix":"10.1007","author":[{"given":"Diane","family":"Mahoney","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,5,29]]},"reference":[{"key":"5_CR20","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1111\/lam.13333","volume":"72","author":"S Ahlawat","year":"2021","unstructured":"Ahlawat, S., Asha & Sharma, K.K. Gut-organ axis: a microbial outreach and networking. Lett Appl Microbiol 72, 636\u2013668 (2021).","journal-title":"Lett Appl Microbiol"},{"key":"5_CR80","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1146\/annurev-publhealth-012420-105020","volume":"42","author":"J Ahn","year":"2021","unstructured":"Ahn, J. & Hayes, R.B. Environmental Influences on the Human Microbiome and Implications for Noncommunicable Disease. Annu Rev Public Health 42, 277\u2013292 (2021).","journal-title":"Annu Rev Public Health"},{"key":"5_CR50","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/1750-9378-7-35","volume":"7","author":"K Alibek","year":"2012","unstructured":"Alibek, K., Karatayeva, N. & Bekniyazov, I. The role of infectious agents in urogenital cancers. Infectious Agents and Cancer 7, 35 (2012).","journal-title":"Infectious Agents and Cancer"},{"key":"5_CR40","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.jcma.2016.04.009","volume":"80","author":"M Amin","year":"2017","unstructured":"Amin, M., Moradi Choghakabodi, P., Alhassan Hamidi, M., Najafian, M. & Farajzadeh Sheikh, A. In vitro antimicrobial activities of metabolites from vaginal Lactobacillus strains against Clostridium perfringens isolated from a woman\u2019s vagina. J Chin Med Assoc 80, 29\u201333 (2017).","journal-title":"J Chin Med Assoc"},{"key":"5_CR46","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1038\/s41598-023-27555-x","volume":"13","author":"AE Asangba","year":"2023","unstructured":"Asangba, A.E., et al. Diagnostic and prognostic potential of the microbiome in ovarian cancer treatment response. Sci Rep 13, 730 (2023).","journal-title":"Sci Rep"},{"key":"5_CR61","doi-asserted-by":"publisher","first-page":"36225","DOI":"10.18632\/oncotarget.16717","volume":"8","author":"S Banerjee","year":"2017","unstructured":"Banerjee, S., et al. The ovarian cancer oncobiome. Oncotarget 8, 36225\u201336245 (2017).","journal-title":"Oncotarget"},{"key":"5_CR65","doi-asserted-by":"publisher","first-page":"101017","DOI":"10.1016\/j.gore.2022.101017","volume":"42","author":"WR Brewster","year":"2022","unstructured":"Brewster, W.R., et al. An evaluation of the microbiota of the upper reproductive tract of women with and without epithelial ovarian cancer. Gynecol Oncol Rep 42, 101017 (2022).","journal-title":"Gynecol Oncol Rep"},{"key":"5_CR3","doi-asserted-by":"publisher","first-page":"1535","DOI":"10.1002\/ijc.34002","volume":"151","author":"CJ Cabasag","year":"2022","unstructured":"Cabasag, C.J., et al. Ovarian cancer today and tomorrow: A global assessment by world region and Human Development Index using GLOBOCAN 2020. Int J Cancer 151, 1535\u20131541 (2022).","journal-title":"Int J Cancer"},{"key":"5_CR25","doi-asserted-by":"publisher","first-page":"15957","DOI":"10.1038\/s41598-017-16289-2","volume":"7","author":"N Castano-Rodriguez","year":"2017","unstructured":"Castano-Rodriguez, N., Goh, K.L., Fock, K.M., Mitchell, H.M. & Kaakoush, N.O. Dysbiosis of the microbiome in gastric carcinogenesis. Sci Rep 7, 15957 (2017).","journal-title":"Sci Rep"},{"key":"5_CR76","doi-asserted-by":"publisher","first-page":"4654","DOI":"10.1158\/0008-5472.CAN-22-0455","volume":"82","author":"LM Chambers","year":"2022","unstructured":"Chambers, L.M., et al. Disruption of the Gut Microbiota Confers Cisplatin Resistance in Epithelial Ovarian Cancer. Cancer Res 82, 4654\u20134669 (2022).","journal-title":"Cancer Res"},{"key":"5_CR5","doi-asserted-by":"crossref","unstructured":"Charkhchi, P., et al. CA125 and Ovarian Cancer: A Comprehensive Review. Cancers (Basel) 12(2020).","DOI":"10.3390\/cancers12123730"},{"key":"5_CR36","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.ygyno.2015.04.036","volume":"138","author":"D Chase","year":"2015","unstructured":"Chase, D., Goulder, A., Zenhausern, F., Monk, B. & Herbst-Kralovetz, M. The vaginal and gastrointestinal microbiomes in gynecologic cancers: a review of applications in etiology, symptoms and treatment. Gynecol Oncol 138, 190\u2013200 (2015).","journal-title":"Gynecol Oncol"},{"key":"5_CR57","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1038\/s41467-017-00901-0","volume":"8","author":"C Chen","year":"2017","unstructured":"Chen, C., et al. The microbiota continuum along the female reproductive tract and its relation to uterine-related diseases. Nat Commun 8, 875 (2017).","journal-title":"Nat Commun"},{"key":"5_CR77","doi-asserted-by":"publisher","first-page":"3309","DOI":"10.1158\/0008-5472.CAN-21-0106","volume":"81","author":"L Chen","year":"2021","unstructured":"Chen, L., et al. Altering the Microbiome Inhibits Tumorigenesis in a Mouse Model of Oviductal High-Grade Serous Carcinoma. Cancer Res 81, 3309\u20133318 (2021).","journal-title":"Cancer Res"},{"key":"5_CR28","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1186\/s12967-021-03154-0","volume":"19","author":"S Choi","year":"2021","unstructured":"Choi, S., Chung, J., Cho, M.L., Park, D. & Choi, S.S. Analysis of changes in microbiome compositions related to the prognosis of colorectal cancer patients based on tissue-derived 16S rRNA sequences. J Transl Med 19, 485 (2021).","journal-title":"J Transl Med"},{"key":"5_CR59","doi-asserted-by":"publisher","first-page":"1063100","DOI":"10.3389\/fonc.2022.1063100","volume":"12","author":"S Ciernikova","year":"2022","unstructured":"Ciernikova, S., Sevcikova, A., Stevurkova, V. & Mego, M. Tumor microbiome - an integral part of the tumor microenvironment. Front Oncol 12, 1063100 (2022).","journal-title":"Front Oncol"},{"key":"5_CR68","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.1210\/me.2014-1108","volume":"28","author":"G Clarke","year":"2014","unstructured":"Clarke, G., et al. Minireview: Gut microbiota: the neglected endocrine organ. Mol Endocrinol 28, 1221\u20131238 (2014).","journal-title":"Mol Endocrinol"},{"key":"5_CR32","doi-asserted-by":"publisher","first-page":"56","DOI":"10.3389\/fcell.2018.00056","volume":"6","author":"EA Comen","year":"2018","unstructured":"Comen, E.A., Bowman, R.L. & Kleppe, M. Underlying Causes and Therapeutic Targeting of the Inflammatory Tumor Microenvironment. Front Cell Dev Biol 6, 56 (2018).","journal-title":"Front Cell Dev Biol"},{"key":"5_CR73","doi-asserted-by":"crossref","unstructured":"D\u2019Amico, F., et al. Gut Microbiota Dynamics during Chemotherapy in Epithelial Ovarian Cancer Patients Are Related to Therapeutic Outcome. Cancers (Basel) 13(2021).","DOI":"10.3390\/cancers13163999"},{"key":"5_CR67","doi-asserted-by":"crossref","unstructured":"D\u2019Antonio, D.L., Marchetti, S., Pignatelli, P., Piattelli, A. & Curia, M.C. The Oncobiome in Gastroenteric and Genitourinary Cancers. Int J Mol Sci 23(2022).","DOI":"10.3390\/ijms23179664"},{"key":"5_CR7","first-page":"937","volume":"93","author":"CA Doubeni","year":"2016","unstructured":"Doubeni, C.A., Doubeni, A.R. & Myers, A.E. Diagnosis and management of ovarian cancer. American Family Physician 93, 937\u2013944 (2016).","journal-title":"American Family Physician"},{"key":"5_CR29","doi-asserted-by":"publisher","first-page":"120","DOI":"10.3389\/fonc.2020.00120","volume":"10","author":"SZ Eslami","year":"2020","unstructured":"Eslami, S.Z., Majidzadeh, A.K., Halvaei, S., Babapirali, F. & Esmaeili, R. Microbiome and Breast Cancer: New Role for an Ancient Population. Front Oncol 10, 120 (2020).","journal-title":"Front Oncol"},{"key":"5_CR51","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1038\/s41416-019-0422-9","volume":"120","author":"RT Fortner","year":"2019","unstructured":"Fortner, R.T., et al. Sexually transmitted infections and risk of epithelial ovarian cancer: results from the Nurses\u2019 Health Studies. Br J Cancer 120, 855\u2013860 (2019).","journal-title":"Br J Cancer"},{"key":"5_CR27","doi-asserted-by":"publisher","first-page":"501","DOI":"10.3748\/wjg.v22.i2.501","volume":"22","author":"J Gagniere","year":"2016","unstructured":"Gagniere, J., et al. Gut microbiota imbalance and colorectal cancer. World J Gastroenterol 22, 501\u2013518 (2016).","journal-title":"World J Gastroenterol"},{"key":"5_CR17","doi-asserted-by":"publisher","first-page":"2317","DOI":"10.1101\/gr.096651.109","volume":"19","author":"Group, N.H.W","year":"2009","unstructured":"Group, N.H.W, et al. The NIH Human Microbiome Project. Genome Res 19, 2317\u20132323 (2009).","journal-title":"Genome Res"},{"key":"5_CR66","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1264\/jsme2.ME17017","volume":"32","author":"ET Hillman","year":"2017","unstructured":"Hillman, E.T., Lu, H., Yao, T. & Nakatsu, C.H. Microbial Ecology along the Gastrointestinal Tract. Microbes Environ 32, 300-313 (2017).","journal-title":"Microbes Environ"},{"issue":"71","key":"5_CR52","first-page":"e71","volume":"202","author":"A Idahl","year":"2010","unstructured":"Idahl, A., et al. Chlamydia trachomatis, Mycoplasma genitalium, Neisseria gonorrhoeae, human papillomavirus, and polyomavirus are not detectable in human tissue with epithelial ovarian cancer, borderline tumor, or benign conditions. Am J Obstet Gynecol 202, 71 e71\u201376 (2010).","journal-title":"Am J Obstet Gynecol"},{"key":"5_CR48","doi-asserted-by":"crossref","unstructured":"Idahl, A., et al. Serologic markers of Chlamydia trachomatis and other sexually transmitted infections and subsequent ovarian cancer risk: Results from the EPIC cohort. Int J Cancer (2020).","DOI":"10.1136\/ijgc-2019-ESGO.922"},{"key":"5_CR53","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13027-019-0223-z","volume":"14","author":"K Ingerslev","year":"2019","unstructured":"Ingerslev, K., et al. The prevalence of EBV and CMV DNA in epithelial ovarian cancer. Infect Agent Cancer 14, 1\u20136 (2019).","journal-title":"Infect Agent Cancer"},{"key":"5_CR45","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.11574","volume":"9","author":"D Jacobson","year":"2021","unstructured":"Jacobson, D., et al. Shifts in gut and vaginal microbiomes are associated with cancer recurrence time in women with ovarian cancer. PeerJ 9, e11574 (2021).","journal-title":"PeerJ"},{"key":"5_CR54","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1016\/j.tranon.2018.02.008","volume":"11","author":"S Jonsson","year":"2018","unstructured":"Jonsson, S., Oda, H., Lundin, E., Olsson, J. & Idahl, A. Chlamydia trachomatis, Chlamydial Heat Shock Protein 60 and Anti-Chlamydial Antibodies in Women with Epithelial Ovarian Tumors. Transl Oncol 11, 546\u2013551 (2018).","journal-title":"Transl Oncol"},{"key":"5_CR33","doi-asserted-by":"crossref","unstructured":"Kumar, L., et al. The Female Reproductive Tract Microbiota: Friends and Foe. Life (Basel) 13(2023).","DOI":"10.3390\/life13061313"},{"key":"5_CR15","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1002\/cam4.2725","volume":"9","author":"S Kyo","year":"2020","unstructured":"Kyo, S., Ishikawa, N., Nakamura, K. & Nakayama, K. The fallopian tube as origin of ovarian cancer: Change of diagnostic and preventive strategies. Cancer Med 9, 421\u2013431 (2020).","journal-title":"Cancer Med"},{"key":"5_CR13","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1038\/s41467-017-00962-1","volume":"8","author":"SI Labidi-Galy","year":"2017","unstructured":"Labidi-Galy, S.I., et al. High grade serous ovarian carcinomas originate in the fallopian tube. Nat Commun 8, 1093 (2017).","journal-title":"Nat Commun"},{"key":"5_CR39","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1038\/s41585-020-0286-z","volume":"17","author":"P Laniewski","year":"2020","unstructured":"Laniewski, P., Ilhan, Z.E. & Herbst-Kralovetz, M.M. The microbiome and gynaecological cancer development, prevention and therapy. Nat Rev Urol 17, 232\u2013250 (2020).","journal-title":"Nat Rev Urol"},{"key":"5_CR81","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1097\/LGT.0000000000000644","volume":"26","author":"A Lev-Sagie","year":"2022","unstructured":"Lev-Sagie, A., et al. The Vaginal Microbiome: II. Vaginal Dysbiotic Conditions. J Low Genit Tract Dis 26, 79\u201384 (2022).","journal-title":"J Low Genit Tract Dis"},{"key":"5_CR47","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.28898","volume":"95","author":"C Li","year":"2023","unstructured":"Li, C., et al. Association between vaginal microbiota and the progression of ovarian cancer. J Med Virol 95, e28898 (2023).","journal-title":"J Med Virol"},{"key":"5_CR12","doi-asserted-by":"crossref","unstructured":"Lisio, M.A., Fu, L., Goyeneche, A., Gao, Z.H. & Telleria, C. High-grade serous ovarian cancer: Basic sciences, clinical and therapeutic standpoints. International Journal of Molecular Sciences 20(2019).","DOI":"10.3390\/ijms20040952"},{"key":"5_CR8","first-page":"533","volume":"26","author":"DE Mahoney","year":"2022","unstructured":"Mahoney, D.E. & Pierce, J.D. Ovarian Cancer Symptom Clusters: Use of the NIH Symptom Science Model for Precision in Symptom Recognition and Management. Clin J Oncol Nurs 26, 533\u2013542 (2022).","journal-title":"Clin J Oncol Nurs"},{"key":"5_CR71","doi-asserted-by":"crossref","unstructured":"Mahoney, D.E., Chalise, P., Rahman, F. & Pierce, J.D. Influences of Gastrointestinal Microbiota Dysbiosis on Serum Proinflammatory Markers in Epithelial Ovarian Cancer Development and Progression. Cancers (Basel) 14(2022).","DOI":"10.3390\/cancers14123022"},{"key":"5_CR24","doi-asserted-by":"publisher","first-page":"667066","DOI":"10.3389\/fendo.2021.667066","volume":"12","author":"JE Martinez","year":"2021","unstructured":"Martinez, J.E., et al. Unhealthy Lifestyle and Gut Dysbiosis: A Better Understanding of the Effects of Poor Diet and Nicotine on the Intestinal Microbiome. Front Endocrinol (Lausanne) 12, 667066 (2021).","journal-title":"Front Endocrinol (Lausanne)"},{"key":"5_CR4","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1002\/uog.17557","volume":"51","author":"KB Mathieu","year":"2018","unstructured":"Mathieu, K.B., Bedi, D.G., Thrower, S.L., Qayyum, A. & Bast, R.C., Jr. Screening for ovarian cancer: Imaging challenges and opportunities for improvement. Ultrasound in Obstetrics & Gynecology 51, 293\u2013303 (2018).","journal-title":"Ultrasound in Obstetrics & Gynecology"},{"key":"5_CR14","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1097\/01.pas.0000180854.28831.77","volume":"30","author":"F Medeiros","year":"2006","unstructured":"Medeiros, F., et al. The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome. Am J Surg Pathol 30, 230\u2013236 (2006).","journal-title":"Am J Surg Pathol"},{"key":"5_CR63","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0227707","volume":"15","author":"R Miao","year":"2020","unstructured":"Miao, R., et al. Assessment of peritoneal microbial features and tumor marker levels as potential diagnostic tools for ovarian cancer. PLoS One 15, e0227707 (2020).","journal-title":"PLoS One"},{"key":"5_CR58","doi-asserted-by":"crossref","unstructured":"Miles, S.M., Hardy, B.L. & Merrell, D.S. Investigation of the microbiota of the reproductive tract in women undergoing a total hysterectomy and bilateral salpingo-oopherectomy. Fertil Steril 107, 813-820 e811 (2017).","DOI":"10.1016\/j.fertnstert.2016.11.028"},{"key":"5_CR44","doi-asserted-by":"publisher","first-page":"146083","DOI":"10.1016\/j.gene.2021.146083","volume":"811","author":"A Morikawa","year":"2022","unstructured":"Morikawa, A., et al. Altered cervicovaginal microbiota in premenopausal ovarian cancer patients. Gene 811, 146083 (2022).","journal-title":"Gene"},{"key":"5_CR35","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1093\/infdis\/jiz342","volume":"220","author":"CA Muzny","year":"2019","unstructured":"Muzny, C.A., et al. An Updated Conceptual Model on the Pathogenesis of Bacterial Vaginosis. J Infect Dis 220, 1399\u20131405 (2019).","journal-title":"J Infect Dis"},{"key":"5_CR43","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1016\/S1470-2045(19)30340-7","volume":"20","author":"NR Nene","year":"2019","unstructured":"Nene, N.R., et al. Association between the cervicovaginal microbiome, BRCA1 mutation status, and risk of ovarian cancer: a case-control study. Lancet Oncol 20, 1171\u20131182 (2019).","journal-title":"Lancet Oncol"},{"key":"5_CR41","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1093\/femsre\/fuu010","volume":"39","author":"H Neuman","year":"2015","unstructured":"Neuman, H., Debelius, J.W., Knight, R. & Koren, O. Microbial endocrinology: the interplay between the microbiota and the endocrine system. FEMS Microbiol Rev 39, 509\u2013521 (2015).","journal-title":"FEMS Microbiol Rev"},{"key":"5_CR69","doi-asserted-by":"crossref","unstructured":"Obrenovich, M.E.M. Leaky Gut, Leaky Brain? Microorganisms 6(2018).","DOI":"10.3390\/microorganisms6040107"},{"key":"5_CR21","doi-asserted-by":"publisher","first-page":"8045646","DOI":"10.1155\/2020\/8045646","volume":"2020","author":"GA Ogunrinola","year":"2020","unstructured":"Ogunrinola, G.A., Oyewale, J.O., Oshamika, O.O. & Olasehinde, G.I. The Human Microbiome and Its Impacts on Health. Int J Microbiol 2020, 8045646 (2020).","journal-title":"Int J Microbiol"},{"key":"5_CR55","doi-asserted-by":"crossref","unstructured":"Pathak, S., Wilczynski, J.R. & Paradowska, E. Factors in Oncogenesis: Viral Infections in Ovarian Cancer. Cancers (Basel) 12(2020).","DOI":"10.3390\/cancers12030561"},{"key":"5_CR75","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1002\/JLB.5HI1117-446RR","volume":"103","author":"A Perales-Puchalt","year":"2018","unstructured":"Perales-Puchalt, A., et al. Frontline Science: Microbiota reconstitution restores intestinal integrity after cisplatin therapy. J Leukoc Biol 103, 799\u2013805 (2018).","journal-title":"J Leukoc Biol"},{"key":"5_CR23","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.1111\/cmi.12308","volume":"16","author":"C Petersen","year":"2014","unstructured":"Petersen, C. & Round, J.L. Defining dysbiosis and its influence on host immunity and disease. Cell Microbiol 16, 1024\u20131033 (2014).","journal-title":"Cell Microbiol"},{"key":"5_CR37","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1016\/j.ygyno.2020.02.002","volume":"157","author":"J Piao","year":"2020","unstructured":"Piao, J., Lee, E.J. & Lee, M. Association between pelvic inflammatory disease and risk of ovarian cancer: An updated meta-analysis. Gynecol Oncol 157, 542\u2013548 (2020).","journal-title":"Gynecol Oncol"},{"key":"5_CR62","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1007\/s13167-022-00286-1","volume":"13","author":"X Qin","year":"2022","unstructured":"Qin, X., et al. Metagenomic analysis of the microbiome of the upper reproductive tract: combating ovarian cancer through predictive, preventive, and personalized medicine. EPMA J 13, 487\u2013498 (2022).","journal-title":"EPMA J"},{"key":"5_CR26","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.trecan.2019.12.007","volume":"6","author":"AG Ramirez-Labrada","year":"2020","unstructured":"Ramirez-Labrada, A.G., et al. The Influence of Lung Microbiota on Lung Carcinogenesis, Immunity, and Immunotherapy. Trends Cancer 6, 86\u201397 (2020).","journal-title":"Trends Cancer"},{"key":"5_CR79","doi-asserted-by":"crossref","unstructured":"Redondo-Useros, N., et al. Microbiota and Lifestyle: A Special Focus on Diet. Nutrients 12(2020).","DOI":"10.3390\/nu12061776"},{"key":"5_CR18","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1177\/0300985815595517","volume":"53","author":"A Rodrigues Hoffmann","year":"2016","unstructured":"Rodrigues Hoffmann, A., Proctor, L.M., Surette, M.G. & Suchodolski, J.S. The Microbiome: The Trillions of Microorganisms That Maintain Health and Cause Disease in Humans and Companion Animals. Vet Pathol 53, 10\u201321 (2016).","journal-title":"Vet Pathol"},{"key":"5_CR72","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.ccell.2014.11.009","volume":"27","author":"MR Rutkowski","year":"2015","unstructured":"Rutkowski, M.R., et al. Microbially driven TLR5-dependent signaling governs distal malignant progression through tumor-promoting inflammation. Cancer Cell 27, 27\u201340 (2015).","journal-title":"Cancer Cell"},{"key":"5_CR30","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0098741","volume":"9","author":"BL Schmidt","year":"2014","unstructured":"Schmidt, B.L., et al. Changes in abundance of oral microbiota associated with oral cancer. PLoS One 9, e98741 (2014).","journal-title":"PLoS One"},{"key":"5_CR49","doi-asserted-by":"publisher","first-page":"2311","DOI":"10.1007\/s10096-012-1570-5","volume":"31","author":"S Shanmughapriya","year":"2012","unstructured":"Shanmughapriya, S., et al. Viral and bacterial aetiologies of epithelial ovarian cancer. Eur J Clin Microbiol Infect Dis 31, 2311\u20132317 (2012).","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"5_CR1","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3322\/caac.21763","volume":"73","author":"RL Siegel","year":"2023","unstructured":"Siegel, R.L., Miller, K.D., Wagle, N.S. & Jemal, A. Cancer statistics, 2023. CA Cancer J Clin 73, 17\u201348 (2023).","journal-title":"CA Cancer J Clin"},{"key":"5_CR42","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/s10020-021-00295-2","volume":"27","author":"A Sipos","year":"2021","unstructured":"Sipos, A., et al. The role of the microbiome in ovarian cancer: mechanistic insights into oncobiosis and to bacterial metabolite signaling. Mol Med 27, 33 (2021).","journal-title":"Mol Med"},{"key":"5_CR34","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1113\/JP271694","volume":"595","author":"SB Smith","year":"2017","unstructured":"Smith, S.B. & Ravel, J. The vaginal microbiota, host defence and reproductive physiology. J Physiol 595, 451\u2013463 (2017).","journal-title":"J Physiol"},{"key":"5_CR11","unstructured":"Society, A.C. American Cancer Society. Cancer Facts & Figures 2021. (American Cancer Society, 2021)."},{"key":"5_CR16","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1002\/path.5145","volume":"246","author":"TR Soong","year":"2018","unstructured":"Soong, T.R., et al. Evidence for lineage continuity between early serous proliferations (ESPs) in the Fallopian tube and disseminated high-grade serous carcinomas. J Pathol 246, 344\u2013351 (2018).","journal-title":"J Pathol"},{"key":"5_CR2","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","volume":"71","author":"H Sung","year":"2021","unstructured":"Sung, H., et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin 71, 209\u2013249 (2021).","journal-title":"CA Cancer J Clin"},{"key":"5_CR9","unstructured":"Surveillance, E., and End Results Program. SEER*Stat Database, 1975-2017. (ed. National Cancer Institute Surveillance, E., and End Results Program) (2020)."},{"key":"5_CR56","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1111\/aogs.12254","volume":"93","author":"MF Svahn","year":"2014","unstructured":"Svahn, M.F., Faber, M.T., Christensen, J., Norrild, B. & Kjaer, S.K. Prevalence of human papillomavirus in epithelial ovarian cancer tissue. A meta-analysis of observational studies. Acta Obstet Gynecol Scand 93, 6\u201319 (2014).","journal-title":"Acta Obstet Gynecol Scand"},{"key":"5_CR74","doi-asserted-by":"publisher","first-page":"8125","DOI":"10.2147\/CMAR.S265205","volume":"12","author":"J Tong","year":"2020","unstructured":"Tong, J., et al. Changes of Intestinal Microbiota in Ovarian Cancer Patients Treated with Surgery and Chemotherapy. Cancer Manag Res 12, 8125\u20138135 (2020).","journal-title":"Cancer Manag Res"},{"issue":"Suppl 1","key":"5_CR19","doi-asserted-by":"publisher","first-page":"S38","DOI":"10.1111\/j.1753-4887.2012.00493.x","volume":"70","author":"LK Ursell","year":"2012","unstructured":"Ursell, L.K., Metcalf, J.L., Parfrey, L.W. & Knight, R. Defining the human microbiome. Nutr Rev 70 Suppl 1, S38\u201344 (2012).","journal-title":"Nutr Rev"},{"key":"5_CR82","doi-asserted-by":"publisher","first-page":"k2179","DOI":"10.1136\/bmj.k2179","volume":"361","author":"AM Valdes","year":"2018","unstructured":"Valdes, A.M., Walter, J., Segal, E. & Spector, T.D. Role of the gut microbiota in nutrition and health. BMJ 361, k2179 (2018).","journal-title":"BMJ"},{"key":"5_CR64","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/s13048-019-0603-4","volume":"13","author":"Q Wang","year":"2020","unstructured":"Wang, Q., et al. The differential distribution of bacteria between cancerous and noncancerous ovarian tissues in situ. J Ovarian Res 13, 8 (2020).","journal-title":"J Ovarian Res"},{"key":"5_CR31","doi-asserted-by":"publisher","first-page":"1911","DOI":"10.3892\/ol.2017.6388","volume":"14","author":"X Xie","year":"2017","unstructured":"Xie, X., Yang, M., Ding, Y. & Chen, J. Microbial infection, inflammation and epithelial ovarian cancer. Oncol Lett 14, 1911\u20131919 (2017).","journal-title":"Oncol Lett"},{"key":"5_CR70","doi-asserted-by":"crossref","unstructured":"Xu, S., Liu, Z., Lv, M., Chen, Y. & Liu, Y. Intestinal dysbiosis promotes epithelial-mesenchymal transition by activating tumor-associated macrophages in ovarian cancer. Pathog Dis 77(2019).","DOI":"10.1093\/femspd\/ftz019"},{"key":"5_CR38","first-page":"743","volume":"10","author":"J Xu","year":"2020","unstructured":"Xu, J., Peng, J.J., Yang, W., Fu, K. & Zhang, Y. Vaginal microbiomes and ovarian cancer: a review. Am J Cancer Res 10, 743\u2013756 (2020).","journal-title":"Am J Cancer Res"},{"key":"5_CR10","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1007\/s13402-020-00513-9","volume":"43","author":"M Yousefi","year":"2020","unstructured":"Yousefi, M., et al. Current insights into the metastasis of epithelial ovarian cancer - hopes and hurdles. Cell Oncol (Dordr) 43, 515\u2013538 (2020).","journal-title":"Cell Oncol (Dordr)"},{"key":"5_CR6","first-page":"188503","volume":"2021","author":"M Zhang","year":"1875","unstructured":"Zhang, M., Cheng, S., Jin, Y., Zhao, Y. & Wang, Y. Roles of CA125 in diagnosis, prediction, and oncogenesis of ovarian cancer. Biochim Biophys Acta Rev Cancer 1875, 188503 (2021).","journal-title":"Biochim Biophys Acta Rev Cancer"},{"key":"5_CR78","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1007\/s10637-020-00906-5","volume":"38","author":"MF Zhao","year":"2020","unstructured":"Zhao, M.F., et al. Novel Bacillus strains from the human gut exert anticancer effects on a broad range of malignancy types. Invest New Drugs 38, 1373\u20131382 (2020).","journal-title":"Invest New Drugs"},{"key":"5_CR22","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1038\/s41422-020-0332-7","volume":"30","author":"D Zheng","year":"2020","unstructured":"Zheng, D., Liwinski, T. & Elinav, E. Interaction between microbiota and immunity in health and disease. Cell Res 30, 492\u2013506 (2020).","journal-title":"Cell Res"},{"key":"5_CR60","doi-asserted-by":"publisher","first-page":"1691","DOI":"10.1038\/s41598-018-38031-2","volume":"9","author":"B Zhou","year":"2019","unstructured":"Zhou, B., et al. The biodiversity Composition of Microbiome in Ovarian Carcinoma Patients. Sci Rep 9, 1691 (2019).","journal-title":"Sci Rep"}],"container-title":["Advances in Experimental Medicine and Biology","Cell and Molecular Biology of Ovarian Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-031-58311-7_5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T11:04:07Z","timestamp":1716894247000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-031-58311-7_5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"ISBN":["9783031583100","9783031583117"],"references-count":82,"URL":"https:\/\/doi.org\/10.1007\/978-3-031-58311-7_5","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"type":"print","value":"0065-2598"},{"type":"electronic","value":"2214-8019"}],"subject":[],"published":{"date-parts":[[2024]]},"assertion":[{"value":"29 May 2024","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}