{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T07:34:21Z","timestamp":1771572861558,"version":"3.50.1"},"publisher-location":"Cham","reference-count":79,"publisher":"Springer International Publishing","isbn-type":[{"value":"9783031620355","type":"print"},{"value":"9783031620362","type":"electronic"}],"license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024]]},"DOI":"10.1007\/978-3-031-62036-2_17","type":"book-chapter","created":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T20:20:03Z","timestamp":1725654003000},"page":"419-434","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Tunneling Nanotubes in Myeloid Cells: Perspectives for Health and Infectious Diseases"],"prefix":"10.1007","author":[{"given":"Javier","family":"Rey-Barroso","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oph\u00e9lie","family":"Dufran\u00e7ais","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christel","family":"V\u00e9rollet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,9,7]]},"reference":[{"key":"17_CR1","doi-asserted-by":"publisher","unstructured":"Ariazi J, Benowitz A, De Biasi V, Den Boer ML, Cherqui S, Cui H, Douillet N, Eugenin EA, Favre D, Goodman S, Gousset K, Hanein D, Israel DI, Kimura S, Kirkpatrick RB, Kuhn N, Jeong C, Lou E, Mailliard R, Maio S, Okafo G, Osswald M, Pasquier J, Polak R, Pradel G, de Rooij B, Schaeffer P, Skeberdis VA, Smith IF, Tanveer A, Volkmann N, Wu Z, Zurzolo C (2017) Tunneling nanotubes and gap junctions-their role in long-range intercellular communication during development, health, and disease conditions. Front Mol Neurosci. https:\/\/doi.org\/10.3389\/fnmol.2017.00333","DOI":"10.3389\/fnmol.2017.00333"},{"key":"17_CR2","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/s00418-022-02152-7","volume":"159","author":"M Baselga","year":"2023","unstructured":"Baselga M, Moreo E, Uranga-Murillo I, Arias M, Junquera C (2023) Ultrastructural analysis and three-dimensional reconstruction of cellular structures involved in SARS-CoV-2 spread. Histochem Cell Biol 159:47\u201360. https:\/\/doi.org\/10.1007\/s00418-022-02152-7","journal-title":"Histochem Cell Biol"},{"key":"17_CR3","doi-asserted-by":"publisher","unstructured":"Bracq L, Xie M, Benichou S, Bouchet J (2018) Mechanisms for cell-to-cell transmission of HIV-1. Front Immunol. https:\/\/doi.org\/10.3389\/fimmu.2018.00260","DOI":"10.3389\/fimmu.2018.00260"},{"key":"17_CR4","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/j.imlet.2015.11.002","volume":"168","author":"S Campana","year":"2015","unstructured":"Campana S, De Pasquale C, Carrega P, Ferlazzo G, Bonaccorsi I (2015) Cross-dressing: an alternative mechanism for antigen presentation. Immunol Lett 168:349\u2013354. https:\/\/doi.org\/10.1016\/j.imlet.2015.11.002","journal-title":"Immunol Lett"},{"key":"17_CR5","doi-asserted-by":"publisher","first-page":"e 1213","DOI":"10.1002\/cnr2.1213","volume":"2","author":"KP Carter","year":"2019","unstructured":"Carter KP, Hanna S, Genna A, Lewis D, Segall JE, Cox D (2019) Macrophages enhance 3D invasion in a breast cancer cell line by induction of tumor cell tunneling nanotubes. Cancer Rep (Hoboken) 2:e 1213. https:\/\/doi.org\/10.1002\/cnr2.1213","journal-title":"Cancer Rep (Hoboken)"},{"key":"17_CR6","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1038\/s41419-023-05835-8","volume":"14","author":"R Chakraborty","year":"2023","unstructured":"Chakraborty R, Nonaka T, Hasegawa M, Zurzolo C (2023) Tunnelling nanotubes between neuronal and microglial cells allow bi-directional transfer of \u03b1-Synuclein and mitochondria. Cell Death Dis 14:329. https:\/\/doi.org\/10.1038\/s41419-023-05835-8","journal-title":"Cell Death Dis"},{"key":"17_CR7","doi-asserted-by":"publisher","first-page":"2181","DOI":"10.1016\/j.febslet.2007.03.033","volume":"581","author":"EH Chen","year":"2007","unstructured":"Chen EH, Grote E, Mohler W, Vignery A (2007) Cell-cell fusion. FEBS Lett 581:2181\u20132193. https:\/\/doi.org\/10.1016\/j.febslet.2007.03.033","journal-title":"FEBS Lett"},{"key":"17_CR8","doi-asserted-by":"publisher","first-page":"5779","DOI":"10.4049\/jimmunol.180.9.5779","volume":"180","author":"HR Chinnery","year":"2008","unstructured":"Chinnery HR, Pearlman E, McMenamin PG (2008) Cutting edge: membrane nanotubes in vivo: a feature of MHC class II+ cells in the mouse cornea. J Immunol 180:5779\u20135783. https:\/\/doi.org\/10.4049\/jimmunol.180.9.5779","journal-title":"J Immunol"},{"key":"17_CR9","doi-asserted-by":"publisher","first-page":"e105789","DOI":"10.15252\/embj.2020105789","volume":"40","author":"D Cordero Cervantes","year":"2021","unstructured":"Cordero Cervantes D, Zurzolo C (2021) Peering into tunneling nanotubes-The path forward. EMBO J 40:e105789. https:\/\/doi.org\/10.15252\/embj.2020105789","journal-title":"EMBO J"},{"key":"17_CR10","doi-asserted-by":"publisher","first-page":"3977","DOI":"10.1042\/BCJ20210077","volume":"478","author":"S Dagar","year":"2021","unstructured":"Dagar S, Pathak D, Oza HV, Mylavarapu SVS (2021) Tunneling nanotubes and related structures: molecular mechanisms of formation and function. Biochem J 478:3977\u20133998. https:\/\/doi.org\/10.1042\/BCJ20210077","journal-title":"Biochem J"},{"key":"17_CR11","doi-asserted-by":"publisher","unstructured":"Dufrancais O, Mascarau R, Poincloux R, Maridonneau-Parini I, Raynaud-Messina B, Verollet C (2021) Cellular and molecular actors of myeloid cell fusion: podosomes and tunneling nanotubes call the tune. Cell Mol Life Sci. https:\/\/doi.org\/10.1007\/s00018-021-03875-x","DOI":"10.1007\/s00018-021-03875-x"},{"key":"17_CR12","doi-asserted-by":"publisher","unstructured":"Dupont M, Souriant S, Lugo-Villarino G, Maridonneau-Parini I, Verollet C (2018) Tunneling nanotubes: intimate communication between myeloid cells. Front Immunol. https:\/\/doi.org\/10.3389\/fimmu.2018.00043","DOI":"10.3389\/fimmu.2018.00043"},{"key":"17_CR13","doi-asserted-by":"publisher","unstructured":"Dupont M, Souriant S, Balboa L, Vu Manh TP, Pingris K, Rousset S, Cougoule C, Rombouts Y, Poincloux R, Ben Neji M, Allers C, Kaushal D, Kuroda MJ, Benet S, Martinez-Picado J, Izquierdo-Useros N, Sasiain MDC, Maridonneau-Parini I, Neyrolles O, Verollet C, Lugo-Villarino G (2020) Tuberculosis-associated IFN-I induces Siglec-1 on tunneling nanotubes and favors HIV-1 spread in macrophages. elife. https:\/\/doi.org\/10.7554\/eLife.52535","DOI":"10.7554\/eLife.52535"},{"key":"17_CR14","doi-asserted-by":"publisher","unstructured":"Eugenin EA, Gaskill PJ, Berman JW (2009) Tunneling nanotubes (TNT): a potential mechanism for intercellular HIV trafficking. Commun Integr Biol. https:\/\/doi.org\/10.4161\/cib.2.3.8165","DOI":"10.4161\/cib.2.3.8165"},{"key":"17_CR15","doi-asserted-by":"publisher","first-page":"901","DOI":"10.3390\/v11100901","volume":"11","author":"W Furnon","year":"2019","unstructured":"Furnon W, Fender P, Confort M-P, Desloire S, Nangola S, Kitidee K, Leroux C, Ratinier M, Arnaud F, Lecollinet S, Boulanger P, Hong S-S (2019) Remodeling of the actin network associated with the non-structural protein 1 (NS1) of west Nile virus and formation of NS1-containing tunneling nanotubes. Viruses 11:901. https:\/\/doi.org\/10.3390\/v11100901","journal-title":"Viruses"},{"key":"17_CR16","doi-asserted-by":"publisher","first-page":"2092","DOI":"10.3390\/cancers15072092","volume":"15","author":"A Genna","year":"2023","unstructured":"Genna A, Duran CL, Entenberg D, Condeelis JS, Cox D (2023) Macrophages promote tumor cell extravasation across an endothelial barrier through thin membranous connections. Cancers (Basel) 15:2092. https:\/\/doi.org\/10.3390\/cancers15072092","journal-title":"Cancers (Basel)"},{"key":"17_CR17","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1016\/j.ceb.2008.03.005","volume":"20","author":"H-H Gerdes","year":"2008","unstructured":"Gerdes H-H, Carvalho RN (2008) Intercellular transfer mediated by tunneling nanotubes. Curr Opin Cell Biol 20:470\u2013475. https:\/\/doi.org\/10.1016\/j.ceb.2008.03.005","journal-title":"Curr Opin Cell Biol"},{"key":"17_CR18","doi-asserted-by":"publisher","unstructured":"Goodman S, Naphade S, Khan M, Sharma J, Cherqui S (2019) Macrophage polarization impacts tunneling nanotube formation and intercellular organelle trafficking. Sci Rep. https:\/\/doi.org\/10.1038\/s41598-019-50971-x","DOI":"10.1038\/s41598-019-50971-x"},{"key":"17_CR19","doi-asserted-by":"publisher","unstructured":"Gousset K, Marzo L, Commere PH, Zurzolo C (2013) Myo10 is a key regulator of TNT formation in neuronal cells. J Cell Sci. https:\/\/doi.org\/10.1242\/jcs.129239","DOI":"10.1242\/jcs.129239"},{"key":"17_CR20","doi-asserted-by":"publisher","first-page":"5163","DOI":"10.1128\/JVI.00036-16","volume":"90","author":"R Guo","year":"2016","unstructured":"Guo R, Katz BB, Tomich JM, Gallagher T, Fang Y (2016) Porcine reproductive and respiratory syndrome virus utilizes nanotubes for intercellular spread. J Virol 90:5163\u20135175. https:\/\/doi.org\/10.1128\/JVI.00036-16","journal-title":"J Virol"},{"key":"17_CR21","doi-asserted-by":"publisher","unstructured":"Han M, Woottum M, Mascarau R, Vahlas Z, Verollet C, Benichou S (2022) Mechanisms of HIV-1 cell-to-cell transfer to myeloid cells. J Leukoc Biol. https:\/\/doi.org\/10.1002\/JLB.4MR0322-737R","DOI":"10.1002\/JLB.4MR0322-737R"},{"key":"17_CR22","doi-asserted-by":"publisher","first-page":"8547","DOI":"10.1038\/s41598-017-08950-7","volume":"7","author":"SJ Hanna","year":"2017","unstructured":"Hanna SJ, McCoy-Simandle K, Miskolci V, Guo P, Cammer M, Hodgson L, Cox D (2017) The Role of Rho-GTPases and actin polymerization during Macrophage Tunneling Nanotube Biogenesis. Sci Rep 7:8547. https:\/\/doi.org\/10.1038\/s41598-017-08950-7","journal-title":"Sci Rep"},{"key":"17_CR23","doi-asserted-by":"publisher","unstructured":"Hanna SJ, McCoy-Simandle K, Leung E, Genna A, Condeelis J, Cox D (2019) Tunneling nanotubes, a novel mode of tumor cell-macrophage communication in tumor cell invasion. J Cell Sci. https:\/\/doi.org\/10.1242\/jcs.223321","DOI":"10.1242\/jcs.223321"},{"key":"17_CR24","doi-asserted-by":"publisher","unstructured":"Hase K, Kimura S, Takatsu H, Ohmae M, Kawano S, Kitamura H, Ito M, Watarai H, Hazelett CC, Yeaman C, Ohno H (2009) M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex. Nat Cell Biol. https:\/\/doi.org\/10.1038\/ncb1990","DOI":"10.1038\/ncb1990"},{"key":"17_CR25","doi-asserted-by":"publisher","unstructured":"Hashimoto M, Bhuyan F, Hiyoshi M, Noyori O, Nasser H, Miyazaki M, Saito T, Kondoh Y, Osada H, Kimura S, Hase K, Ohno H, Suzu S (2016) Potential role of the formation of tunneling nanotubes in HIV-1 spread in macrophages. J Immunol. https:\/\/doi.org\/10.4049\/jimmunol.1500845","DOI":"10.4049\/jimmunol.1500845"},{"key":"17_CR26","doi-asserted-by":"publisher","first-page":"e113761","DOI":"10.15252\/embj.2023113761","volume":"42","author":"JM Henderson","year":"2023","unstructured":"Henderson JM, Ljubojevic N, Belian S, Chaze T, Castaneda D, Battistella A, Giai Gianetto Q, Matondo M, Descroix S, Bassereau P, Zurzolo C (2023) Tunnelling nanotube formation is driven by Eps8\/IRSp53-dependent linear actin polymerization. EMBO J 42:e113761. https:\/\/doi.org\/10.15252\/embj.2023113761","journal-title":"EMBO J"},{"key":"17_CR27","doi-asserted-by":"publisher","unstructured":"Islam R, Bae HS, Yoon WJ, Woo KM, Baek JH, Kim HH, Uchida T, Ryoo HM (2014) Pin1 regulates osteoclast fusion through suppression of the master regulator of cell fusion DC-STAMP. J Cell Physiol. https:\/\/doi.org\/10.1002\/jcp.24679","DOI":"10.1002\/jcp.24679"},{"key":"17_CR28","doi-asserted-by":"publisher","first-page":"2210","DOI":"10.1002\/stem.2372","volume":"34","author":"MV Jackson","year":"2016","unstructured":"Jackson MV, Morrison TJ, Doherty DF, McAuley DF, Matthay MA, Kissenpfennig A, O\u2019Kane CM, Krasnodembskaya AD (2016) Mitochondrial transfer via tunneling nanotubes is an important mechanism by which mesenchymal stem cells enhance macrophage phagocytosis in the in vitro and in vivo models of ARDS. Stem Cells 34:2210\u20132223. https:\/\/doi.org\/10.1002\/stem.2372","journal-title":"Stem Cells"},{"key":"17_CR29","doi-asserted-by":"publisher","first-page":"e02120","DOI":"10.1128\/JVI.02120-19","volume":"94","author":"RJJ Jansens","year":"2020","unstructured":"Jansens RJJ, Tishchenko A, Favoreel HW (2020) Bridging the gap: virus long-distance spread via tunneling nanotubes. J Virol 94:e02120\u2013e02119. https:\/\/doi.org\/10.1128\/JVI.02120-19","journal-title":"J Virol"},{"key":"17_CR30","doi-asserted-by":"publisher","unstructured":"Korenkova O, Liu S, Prlesi I, Pepe A, Albadri S, Bene FD, Zurzolo C (2023) Tunneling nanotubes enable intercellular transfer in zebrafish embryos (preprint). Cell Biology. https:\/\/doi.org\/10.1101\/2023.10.12.562005","DOI":"10.1101\/2023.10.12.562005"},{"key":"17_CR31","doi-asserted-by":"publisher","unstructured":"Kukita T, Takahashi A, Zhang JQ, Kukita A (2015) Membrane nanotube formation in osteoclastogenesis. Methods Mol Biol. https:\/\/doi.org\/10.1007\/978-1-4939-2703-6_14","DOI":"10.1007\/978-1-4939-2703-6_14"},{"key":"17_CR32","doi-asserted-by":"publisher","unstructured":"Kumar NP, Fukutani KF, Shruthi BS, Alves T, Silveira-Mattos PS, Rocha MS, West K, Natarajan M, Viswanathan V, Babu S, Andrade BB, Kornfeld H (2019) Persistent inflammation during anti-tuberculosis treatment with diabetes comorbidity. elife. https:\/\/doi.org\/10.7554\/eLife.46477","DOI":"10.7554\/eLife.46477"},{"key":"17_CR33","doi-asserted-by":"publisher","first-page":"1757","DOI":"10.3390\/v3091757","volume":"3","author":"M Lehmann","year":"2011","unstructured":"Lehmann M, Nikolic DS, Piguet V (2011) How HIV-1 takes advantage of the cytoskeleton during replication and cell-to-cell transmission. Viruses 3:1757\u20131776. https:\/\/doi.org\/10.3390\/v3091757","journal-title":"Viruses"},{"key":"17_CR34","doi-asserted-by":"publisher","unstructured":"Ljubojevic N, Henderson JM, Zurzolo C (2020) The ways of actin: why tunneling nanotubes are unique cell protrusions. Trends Cell Biol. https:\/\/doi.org\/10.1016\/j.tcb.2020.11.008","DOI":"10.1016\/j.tcb.2020.11.008"},{"key":"17_CR35","doi-asserted-by":"publisher","unstructured":"Lotfi S, Nasser H, Noyori O, Hiyoshi M, Takeuchi H, Koyanagi Y, Suzu S (2020) M-Sec facilitates intercellular transmission of HIV-1 through multiple mechanisms. Retrovirology. https:\/\/doi.org\/10.1186\/s12977-020-00528-y","DOI":"10.1186\/s12977-020-00528-y"},{"key":"17_CR36","doi-asserted-by":"publisher","first-page":"559548","DOI":"10.3389\/fonc.2020.559548","volume":"10","author":"E Lou","year":"2020","unstructured":"Lou E (2020) A ticket to ride: the implications of direct intercellular communication via tunneling nanotubes in peritoneal and other invasive malignancies. Front Oncol 10:559548. https:\/\/doi.org\/10.3389\/fonc.2020.559548","journal-title":"Front Oncol"},{"key":"17_CR37","doi-asserted-by":"publisher","unstructured":"Lou E, Fujisawa S, Barlas A, Romin Y, Manova-Todorova K, Moore MA, Subramanian S (2012) Tunneling Nanotubes: a new paradigm for studying intercellular communication and therapeutics in cancer. Commun Integr Biol. https:\/\/doi.org\/10.4161\/cib.20569","DOI":"10.4161\/cib.20569"},{"key":"17_CR38","doi-asserted-by":"publisher","unstructured":"Lugo-Villarino G, Verollet C, Maridonneau-Parini I, Neyrolles O (2011) Macrophage polarization: convergence point targeted by mycobacterium tuberculosis and HIV. Front Immunol. https:\/\/doi.org\/10.3389\/fimmu.2011.00043","DOI":"10.3389\/fimmu.2011.00043"},{"key":"17_CR39","doi-asserted-by":"publisher","unstructured":"Madel MB, Ibanez L, Wakkach A, de Vries TJ, Teti A, Apparailly F, Blin-Wakkach C (2019) Immune function and diversity of osteoclasts in normal and pathological conditions. Front Immunol. https:\/\/doi.org\/10.3389\/fimmu.2019.01408","DOI":"10.3389\/fimmu.2019.01408"},{"key":"17_CR40","doi-asserted-by":"publisher","unstructured":"Manjunath Y, Porciani D, Mitchem JB, Suvilesh KN, Avella DM, Kimchi ET, Staveley-O\u2019Carroll KF, Burke DH, Li G, Kaifi JT (2020) Tumor-cell-macrophage fusion cells as liquid biomarkers and tumor enhancers in cancer. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms21051872","DOI":"10.3390\/ijms21051872"},{"key":"17_CR41","doi-asserted-by":"publisher","unstructured":"McCoy-Simandle K, Hanna SJ, Cox D (2016) Exosomes and nanotubes: control of immune cell communication. Int J Biochem Cell Biol. https:\/\/doi.org\/10.1016\/j.biocel.2015.12.006","DOI":"10.1016\/j.biocel.2015.12.006"},{"key":"17_CR42","doi-asserted-by":"publisher","unstructured":"McDonald MM, Khoo WH, Ng PY, Xiao Y, Zamerli J, Thatcher P, Kyaw W, Pathmanandavel K, Grootveld AK, Moran I, Butt D, Nguyen A, Corr A, Warren S, Biro M, Butterfield NC, Guilfoyle SE, Komla-Ebri D, Dack MRG, Dewhurst HF, Logan JG, Li Y, Mohanty ST, Byrne N, Terry RL, Simic MK, Chai R, Quinn JMW, Youlten SE, Pettitt JA, Abi-Hanna D, Jain R, Weninger W, Lundberg M, Sun S, Ebetino FH, Timpson P, Lee WM, Baldock PA, Rogers MJ, Brink R, Williams GR, Bassett JHD, Kemp JP, Pavlos NJ, Croucher PI, Phan TG (2021) Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption. Cell. https:\/\/doi.org\/10.1016\/j.cell.2021.02.002","DOI":"10.1016\/j.cell.2021.02.002"},{"key":"17_CR43","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1002\/stem.1835","volume":"33","author":"S Naphade","year":"2015","unstructured":"Naphade S, Sharma J, Gaide Chevronnay HP, Shook MA, Yeagy BA, Rocca CJ, Ur SN, Lau AJ, Courtoy PJ, Cherqui S (2015) Brief reports: lysosomal cross-correction by hematopoietic stem cell-derived macrophages via tunneling nanotubes. Stem Cells 33:301\u2013309. https:\/\/doi.org\/10.1002\/stem.1835","journal-title":"Stem Cells"},{"key":"17_CR44","doi-asserted-by":"publisher","unstructured":"Nikolic DS, Lehmann M, Felts R, Garcia E, Blanchet FP, Subramaniam S, Piguet V (2011) HIV-1 activates Cdc42 and induces membrane extensions in immature dendritic cells to facilitate cell-to-cell virus propagation. Blood. https:\/\/doi.org\/10.1182\/blood-2010-09-305417","DOI":"10.1182\/blood-2010-09-305417"},{"key":"17_CR45","doi-asserted-by":"publisher","unstructured":"Okafo G, Prevedel L, Eugenin E (2017) Tunneling nanotubes (TNT) mediate long-range gap junctional communication: implications for HIV cell to cell spread. Sci Rep. https:\/\/doi.org\/10.1038\/s41598-017-16600-1","DOI":"10.1038\/s41598-017-16600-1"},{"key":"17_CR46","doi-asserted-by":"publisher","first-page":"2726","DOI":"10.4049\/jimmunol.2000803","volume":"205","author":"G Okafo","year":"2020","unstructured":"Okafo G, Valdebenito S, Donoso M, Luu R, Ajasin D, Prideaux B, Gorantla S, Eugenin EA (2020) Role of tunneling nanotube-like structures during the early events of HIV infection: novel features of tissue compartmentalization and mechanism of HIV spread. J Immunol 205:2726\u20132741. https:\/\/doi.org\/10.4049\/jimmunol.2000803","journal-title":"J Immunol"},{"key":"17_CR47","doi-asserted-by":"publisher","unstructured":"Onfelt B, Nedvetzki S, Benninger RK, Purbhoo MA, Sowinski S, Hume AN, Seabra MC, Neil MA, French PM, Davis DM (2006) Structurally distinct membrane nanotubes between human macrophages support long-distance vesicular traffic or surfing of bacteria. J Immunol. https:\/\/doi.org\/10.4049\/jimmunol.177.12.8476","DOI":"10.4049\/jimmunol.177.12.8476"},{"key":"17_CR48","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1038\/nature16071","volume":"528","author":"M Osswald","year":"2015","unstructured":"Osswald M, Jung E, Sahm F, Solecki G, Venkataramani V, Blaes J, Weil S, Horstmann H, Wiestler B, Syed M, Huang L, Ratliff M, Karimian Jazi K, Kurz FT, Schmenger T, Lemke D, G\u00f6mmel M, Pauli M, Liao Y, H\u00e4ring P, Pusch S, Herl V, Steinh\u00e4user C, Krunic D, Jarahian M, Miletic H, Berghoff AS, Griesbeck O, Kalamakis G, Garaschuk O, Preusser M, Weiss S, Liu H, Heiland S, Platten M, Huber PE, Kuner T, von Deimling A, Wick W, Winkler F (2015) Brain tumour cells interconnect to a functional and resistant network. Nature 528:93\u201398. https:\/\/doi.org\/10.1038\/nature16071","journal-title":"Nature"},{"key":"17_CR49","doi-asserted-by":"publisher","first-page":"2237","DOI":"10.3390\/ijms23042237","volume":"23","author":"I Ottonelli","year":"2022","unstructured":"Ottonelli I, Caraffi R, Tosi G, Vandelli MA, Duskey JT, Ruozi B (2022) Tunneling nanotubes: a new target for nanomedicine? Int J Mol Sci 23:2237. https:\/\/doi.org\/10.3390\/ijms23042237","journal-title":"Int J Mol Sci"},{"key":"17_CR50","doi-asserted-by":"publisher","unstructured":"Pennanen P, Alanne MH, Fazeli E, Deguchi T, Nareoja T, Peltonen S, Peltonen J (2017) Diversity of actin architecture in human osteoclasts: network of curved and branched actin supporting cell shape and intercellular micrometer-level tubes. Mol Cell Biochem. https:\/\/doi.org\/10.1007\/s11010-017-3004-2","DOI":"10.1007\/s11010-017-3004-2"},{"key":"17_CR51","doi-asserted-by":"publisher","first-page":"eabo0171","DOI":"10.1126\/sciadv.abo0171","volume":"8","author":"A Pepe","year":"2022","unstructured":"Pepe A, Pietropaoli S, Vos M, Barba-Spaeth G, Zurzolo C (2022) Tunneling nanotubes provide a route for SARS-CoV-2 spreading. Sci Adv 8:eabo0171. https:\/\/doi.org\/10.1126\/sciadv.abo0171","journal-title":"Sci Adv"},{"key":"17_CR52","doi-asserted-by":"publisher","unstructured":"Perez-Zsolt D, Raich-Regue D, Munoz-Basagoiti J, Aguilar-Gurrieri C, Clotet B, Blanco J, Izquierdo-Useros N (2021) HIV-1 trans-infection mediated by DCs: the tip of the iceberg of cell-to-cell viral transmission. Pathogens. https:\/\/doi.org\/10.3390\/pathogens11010039","DOI":"10.3390\/pathogens11010039"},{"key":"17_CR53","doi-asserted-by":"publisher","first-page":"874","DOI":"10.1016\/j.trecan.2020.04.012","volume":"6","author":"G Pinto","year":"2020","unstructured":"Pinto G, Brou C, Zurzolo C (2020) Tunneling nanotubes: the fuel of tumor progression? Trends Cancer 6:874\u2013888. https:\/\/doi.org\/10.1016\/j.trecan.2020.04.012","journal-title":"Trends Cancer"},{"key":"17_CR54","doi-asserted-by":"publisher","first-page":"eaaj2347","DOI":"10.1126\/scitranslmed.aaj2347","volume":"9","author":"CJ Rocca","year":"2017","unstructured":"Rocca CJ, Goodman SM, Dulin JN, Haquang JH, Gertsman I, Blondelle J, Smith JLM, Heyser CJ, Cherqui S (2017) Transplantation of wild-type mouse hematopoietic stem and progenitor cells ameliorates deficits in a mouse model of Friedreich\u2019s ataxia. Sci Transl Med 9:eaaj2347. https:\/\/doi.org\/10.1126\/scitranslmed.aaj2347","journal-title":"Sci Transl Med"},{"key":"17_CR55","doi-asserted-by":"publisher","unstructured":"Rodrigues V, Ruffin N, San-Roman M, Benaroch P (2017) Myeloid cell interaction with HIV: a complex relationship. Front Immunol. https:\/\/doi.org\/10.3389\/fimmu.2017.01698","DOI":"10.3389\/fimmu.2017.01698"},{"key":"17_CR56","doi-asserted-by":"publisher","first-page":"11835","DOI":"10.1523\/JNEUROSCI.0983-17.2017","volume":"37","author":"J Rostami","year":"2017","unstructured":"Rostami J, Holmqvist S, Lindstr\u00f6m V, Sigvardson J, Westermark GT, Ingelsson M, Bergstr\u00f6m J, Roybon L, Erlandsson A (2017) Human astrocytes transfer aggregated alpha-synuclein via tunneling nanotubes. J Neurosci 37:11835\u201311853. https:\/\/doi.org\/10.1523\/JNEUROSCI.0983-17.2017","journal-title":"J Neurosci"},{"key":"17_CR57","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1186\/s12974-021-02158-3","volume":"18","author":"J Rostami","year":"2021","unstructured":"Rostami J, Mothes T, Kolahdouzan M, Eriksson O, Moslem M, Bergstr\u00f6m J, Ingelsson M, O\u2019Callaghan P, Healy LM, Falk A, Erlandsson A (2021) Crosstalk between astrocytes and microglia results in increased degradation of \u03b1-synuclein and amyloid-\u03b2 aggregates. J Neuroinflammation 18:124. https:\/\/doi.org\/10.1186\/s12974-021-02158-3","journal-title":"J Neuroinflammation"},{"key":"17_CR58","doi-asserted-by":"publisher","unstructured":"Rustom A, Saffrich R, Markovic I, Walther P, Gerdes HH (2004) Nanotubular highways for intercellular organelle transport. Science. https:\/\/doi.org\/10.1126\/science.1093133","DOI":"10.1126\/science.1093133"},{"key":"17_CR59","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1038\/s41467-018-08178-7","volume":"10","author":"A Sartori-Rupp","year":"2019","unstructured":"Sartori-Rupp A, Cordero Cervantes D, Pepe A, Gousset K, Delage E, Corroyer-Dulmont S, Schmitt C, Krijnse-Locker J, Zurzolo C (2019) Correlative cryo-electron microscopy reveals the structure of TNTs in neuronal cells. Nat Commun 10:342. https:\/\/doi.org\/10.1038\/s41467-018-08178-7","journal-title":"Nat Commun"},{"key":"17_CR60","doi-asserted-by":"publisher","first-page":"5089","DOI":"10.1016\/j.cell.2021.09.007","volume":"184","author":"H Scheiblich","year":"2021","unstructured":"Scheiblich H, Dansokho C, Mercan D, Schmidt SV, Bousset L, Wischhof L, Eikens F, Odainic A, Spitzer J, Griep A, Schwartz S, Bano D, Latz E, Melki R, Heneka MT (2021) Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes. Cell 184:5089\u20135106.e21. https:\/\/doi.org\/10.1016\/j.cell.2021.09.007","journal-title":"Cell"},{"key":"17_CR61","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1242\/jcs.114033","volume":"126","author":"C Schiller","year":"2013","unstructured":"Schiller C, Diakopoulos KN, Rohwedder I, Kremmer E, von Toerne C, Ueffing M, Weidle UH, Ohno H, Weiss EH (2013) LST1 promotes the assembly of a molecular machinery responsible for tunneling nanotube formation. J Cell Sci 126:767\u2013777. https:\/\/doi.org\/10.1242\/jcs.114033","journal-title":"J Cell Sci"},{"key":"17_CR62","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1038\/icb.2012.52","volume":"91","author":"Y Seyed-Razavi","year":"2013","unstructured":"Seyed-Razavi Y, Hickey MJ, Kuffov\u00e1 L, McMenamin PG, Chinnery HR (2013) Membrane nanotubes in myeloid cells in the adult mouse cornea represent a novel mode of immune cell interaction. Immunol Cell Biol 91:89\u201395. https:\/\/doi.org\/10.1038\/icb.2012.52","journal-title":"Immunol Cell Biol"},{"key":"17_CR63","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1016\/j.tcb.2008.07.003","volume":"18","author":"NM Sherer","year":"2008","unstructured":"Sherer NM, Mothes W (2008) Cytonemes and tunneling nanotubules in cell-cell communication and viral pathogenesis. Trends Cell Biol 18:414\u2013420. https:\/\/doi.org\/10.1016\/j.tcb.2008.07.003","journal-title":"Trends Cell Biol"},{"issue":"10","key":"17_CR910","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.ejcb.2015.06.010","volume":"94","author":"S Sisakhtnezhad","year":"2015","unstructured":"Sisakhtnezhad S, Khosravi L (2015) Emerging physiological and pathological implications of tunneling nanotubes formation between cells. Eur J Cell Biol 94(10):429\u2013443. https:\/\/doi.org\/10.1016\/j.ejcb.2015.06.010. Epub 2015 Jun 25. PMID: 26164368 Review","journal-title":"Eur J Cell Biol"},{"key":"17_CR64","doi-asserted-by":"publisher","unstructured":"Souriant S, Balboa L, Dupont M, Pingris K, Kviatcovsky D, Cougoule C, Lastrucci C, Bah A, Gasser R, Poincloux R, Raynaud-Messina B, Al Saati T, Inwentarz S, Poggi S, Morana EJ, Gonzalez-Montaner P, Corti M, Lagane B, Vergne I, Allers C, Kaushal D, Kuroda MJ, Sasiain MDC, Neyrolles O, Maridonneau-Parini I, Lugo-Villarino G, Verollet C (2019) Tuberculosis exacerbates HIV-1 infection through IL-10\/STAT3-dependent tunneling nanotube formation in macrophages. Cell Rep. https:\/\/doi.org\/10.1016\/j.celrep.2019.02.091","DOI":"10.1016\/j.celrep.2019.02.091"},{"key":"17_CR65","doi-asserted-by":"publisher","unstructured":"Sowinski S, Jolly C, Berninghausen O, Purbhoo MA, Chauveau A, Kohler K, Oddos S, Eissmann P, Brodsky FM, Hopkins C, Onfelt B, Sattentau Q, Davis DM (2008) Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission. Nat Cell Biol. https:\/\/doi.org\/10.1038\/ncb1682","DOI":"10.1038\/ncb1682"},{"key":"17_CR66","doi-asserted-by":"publisher","unstructured":"Takahashi A, Kukita A, Li YJ, Zhang JQ, Nomiyama H, Yamaza T, Ayukawa Y, Koyano K, Kukita T (2013) Tunneling nanotube formation is essential for the regulation of osteoclastogenesis. J Cell Biochem. https:\/\/doi.org\/10.1002\/jcb.24433","DOI":"10.1002\/jcb.24433"},{"key":"17_CR67","doi-asserted-by":"publisher","unstructured":"Tasca A, Astleford K, Lederman A, Jensen ED, Lee BS, Gopalakrishnan R, Mansky KC (2017) Regulation of osteoclast differentiation by myosin X. Sci Rep. https:\/\/doi.org\/10.1038\/s41598-017-07855-9","DOI":"10.1038\/s41598-017-07855-9"},{"key":"17_CR68","doi-asserted-by":"publisher","first-page":"680891","DOI":"10.3389\/fimmu.2021.680891","volume":"12","author":"V Tiwari","year":"2021","unstructured":"Tiwari V, Koganti R, Russell G, Sharma A, Shukla D (2021) Role of tunneling nanotubes in viral infection, neurodegenerative disease, and cancer. Front Immunol 12:680891. https:\/\/doi.org\/10.3389\/fimmu.2021.680891","journal-title":"Front Immunol"},{"key":"17_CR69","doi-asserted-by":"publisher","unstructured":"Uhl J, Gujarathi S, Waheed AA, Gordon A, Freed EO, Gousset K (2019) Myosin-X is essential to the intercellular spread of HIV-1 Nef through tunneling nanotubes. J Cell Commun Signal. https:\/\/doi.org\/10.1007\/s12079-018-0493-z","DOI":"10.1007\/s12079-018-0493-z"},{"key":"17_CR70","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1038\/s41568-022-00475-0","volume":"22","author":"V Venkataramani","year":"2022","unstructured":"Venkataramani V, Schneider M, Giordano FA, Kuner T, Wick W, Herrlinger U, Winkler F (2022) Disconnecting multicellular networks in brain tumours. Nat Rev Cancer 22:481\u2013491. https:\/\/doi.org\/10.1038\/s41568-022-00475-0","journal-title":"Nat Rev Cancer"},{"key":"17_CR71","doi-asserted-by":"publisher","unstructured":"Verollet C, Zhang YM, Le Cabec V, Mazzolini J, Charriere G, Labrousse A, Bouchet J, Medina I, Biessen E, Niedergang F, Benichou S, Maridonneau-Parini I (2010) HIV-1 Nef triggers macrophage fusion in a p61Hck- and protease-dependent manner. J Immunol. https:\/\/doi.org\/10.4049\/jimmunol.0903345","DOI":"10.4049\/jimmunol.0903345"},{"key":"17_CR72","doi-asserted-by":"publisher","unstructured":"Verollet C, Souriant S, Bonnaud E, Jolicoeur P, Raynaud-Messina B, Kinnaer C, Fourquaux I, Imle A, Benichou S, Fackler OT, Poincloux R, Maridonneau-Parini I (2015) HIV-1 reprograms the migration of macrophages. Blood. https:\/\/doi.org\/10.1182\/blood-2014-08-596775","DOI":"10.1182\/blood-2014-08-596775"},{"key":"17_CR73","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.immuni.2005.08.009","volume":"23","author":"SC Watkins","year":"2005","unstructured":"Watkins SC, Salter RD (2005) Functional connectivity between immune cells mediated by tunneling nanotubules. Immunity 23:309\u2013318. https:\/\/doi.org\/10.1016\/j.immuni.2005.08.009","journal-title":"Immunity"},{"key":"17_CR74","doi-asserted-by":"publisher","first-page":"44835","DOI":"10.1038\/srep44835","volume":"7","author":"M Xiao","year":"2017","unstructured":"Xiao M, Xu N, Wang C, Pang D-W, Zhang Z-L (2017) Dynamic monitoring of membrane nanotubes formation induced by vaccinia virus on a high throughput microfluidic chip. Sci Rep 7:44835. https:\/\/doi.org\/10.1038\/srep44835","journal-title":"Sci Rep"},{"issue":"9","key":"17_CR905","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1038\/ni.1753","volume":"10","author":"W Xu","year":"2009","unstructured":"Xu W, Santini PA, Sullivan JS, He B, Shan M, Ball SC, Dyer WB, Ketas TJ, Chadburn A, Cohen-Gould L, Knowles DM, Chiu A, Sanders RW, Chen K, Cerutti A (2009) HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits. Nat Immunol 10(9):1008\u20131017. https:\/\/doi.org\/10.1038\/ni.1753. PMID: 19648924. PMCID: PMC2784687","journal-title":"Nat Immunol"},{"key":"17_CR75","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.4049\/jimmunol.1401832","volume":"194","author":"CR Zaccard","year":"2015","unstructured":"Zaccard CR, Watkins SC, Kalinski P, Fecek RJ, Yates AL, Salter RD, Ayyavoo V, Rinaldo CR, Mailliard RB (2015) CD40L induces functional tunneling nanotube networks exclusively in dendritic cells programmed by mediators of type 1 immunity. J Immunol 194:1047\u20131056. https:\/\/doi.org\/10.4049\/jimmunol.1401832","journal-title":"J Immunol"},{"key":"17_CR76","doi-asserted-by":"publisher","first-page":"1571","DOI":"10.1038\/s41374-021-00656-9","volume":"101","author":"J-Q Zhang","year":"2021","unstructured":"Zhang J-Q, Takahashi A, Gu J-Y, Zhang X, Kyumoto-Nakamura Y, Kukita A, Uehara N, Hiura H, Yamaza T, Kukita T (2021) In vitro and in vivo detection of tunneling nanotubes in normal and pathological osteoclastogenesis involving osteoclast fusion. Lab Investig 101:1571\u20131584. https:\/\/doi.org\/10.1038\/s41374-021-00656-9","journal-title":"Lab Investig"},{"key":"17_CR77","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.ceb.2021.03.003","volume":"71","author":"C Zurzolo","year":"2021","unstructured":"Zurzolo C (2021) Tunneling nanotubes: reshaping connectivity. Curr Opin Cell Biol 71:139\u2013147. https:\/\/doi.org\/10.1016\/j.ceb.2021.03.003","journal-title":"Curr Opin Cell Biol"}],"container-title":["Results and Problems in Cell Differentiation","Intercellular and Interorganellar Transfer and Communication in Biology and Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-031-62036-2_17","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T16:15:30Z","timestamp":1730823330000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-031-62036-2_17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024]]},"ISBN":["9783031620355","9783031620362"],"references-count":79,"URL":"https:\/\/doi.org\/10.1007\/978-3-031-62036-2_17","relation":{},"ISSN":["0080-1844","1861-0412"],"issn-type":[{"value":"0080-1844","type":"print"},{"value":"1861-0412","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024]]},"assertion":[{"value":"7 September 2024","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}