{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T01:05:37Z","timestamp":1768007137373,"version":"3.49.0"},"publisher-location":"Cham","reference-count":13,"publisher":"Springer Nature Switzerland","isbn-type":[{"value":"9783031765490","type":"print"},{"value":"9783031765506","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"DOI":"10.1007\/978-3-031-76550-6_34","type":"book-chapter","created":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T20:46:45Z","timestamp":1739220405000},"page":"207-212","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association Between C22:5-Containing Lipids and RPE Pathologies in Mice with Tmem135 Overexpression"],"prefix":"10.1007","author":[{"given":"Michael","family":"Landowski","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sakae","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiro","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,2,11]]},"reference":[{"key":"34_CR1","doi-asserted-by":"publisher","first-page":"6099","DOI":"10.1038\/s41467-023-41849-8","volume":"14","author":"D Hu","year":"2023","unstructured":"Hu D, Tan M, Lu D, et al. TMEM135 links peroxisomes to the regulation of brown fat mitochondrial fission and energy homeostasis. Nat Commun. 2023;14:6099.","journal-title":"Nat Commun"},{"key":"34_CR2","doi-asserted-by":"publisher","first-page":"1138428","DOI":"10.3389\/fpubh.2023.1138428","volume":"11","author":"B Jiang","year":"2023","unstructured":"Jiang B, Jiang C, Li J, Lu P. Trends and disparities in disease burden of age-related macular degeneration from 1990 to 2019: results from the global burden of disease study 2019. Front Public Health. 2023;11:1138428.","journal-title":"Front Public Health"},{"key":"34_CR3","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.preteyeres.2016.04.003","volume":"54","author":"NG Lambert","year":"2016","unstructured":"Lambert NG, ElShelmani H, Singh MK, et al. Risk factors and biomarkers of age-related macular degeneration. Prog Retin Eye Res. 2016;54:64\u2013102.","journal-title":"Prog Retin Eye Res"},{"key":"34_CR4","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1167\/iovs.61.12.16","volume":"61","author":"M Landowski","year":"2020","unstructured":"Landowski M, Grindel S, Shahi PK, et al. Modulation of Tmem135 leads to retinal pigmented epithelium pathologies in mice. Invest Ophthalmol Vis Sci. 2020;61:16.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"34_CR5","doi-asserted-by":"publisher","unstructured":"Landowski M, Grindel S, Hao Y, et al. A protocol to evaluate and quantify retinal pigmented epithelium pathologies in mouse models of age-related macular degeneration. J Vis Exp. 2023a;10 https:\/\/doi.org\/10.3791\/64927.","DOI":"10.3791\/64927"},{"key":"34_CR6","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1038\/s42003-022-04404-7","volume":"6","author":"M Landowski","year":"2023","unstructured":"Landowski M, Bhute VJ, Grindel S, et al. Transmembrane protein 135 regulates lipid homeostasis through its role in peroxisomal DHA metabolism. Commun Biol. 2023b;6:8.","journal-title":"Commun Biol"},{"key":"34_CR7","doi-asserted-by":"publisher","first-page":"e19264","DOI":"10.7554\/eLife.19264","volume":"5","author":"WH Lee","year":"2016","unstructured":"Lee WH, Higuchi H, Ikeda S, et al. Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies. elife. 2016;5:e19264.","journal-title":"elife"},{"key":"34_CR8","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2021.101037","volume":"89","author":"D Lewandowski","year":"2022","unstructured":"Lewandowski D, Sander CL, Tworak A, et al. Dynamic lipid turnover in photoreceptors and retinal pigment epithelium throughout life. Prog Retin Eye Res. 2022;89:101037.","journal-title":"Prog Retin Eye Res"},{"key":"34_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ajo.2012.10.018","volume":"155","author":"JW Miller","year":"2013","unstructured":"Miller JW. Age-related macular degeneration revisited\u2013piecing the puzzle: the LXIX Edward Jackson memorial lecture. Am J Ophthalmol. 2013;155:1\u201335. e13","journal-title":"Am J Ophthalmol"},{"key":"34_CR10","doi-asserted-by":"publisher","first-page":"4021","DOI":"10.1073\/pnas.83.11.4021","volume":"83","author":"M Neuringer","year":"1986","unstructured":"Neuringer M, Connor WE, Lin DS, et al. Biochemical and functional effects of prenatal and postnatal omega 3 fatty acid deficiency on retina and brain in rhesus monkeys. Proc Natl Acad Sci USA. 1986;83:4021\u20135.","journal-title":"Proc Natl Acad Sci USA"},{"key":"34_CR11","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/539426","volume":"2012","author":"E Patterson","year":"2012","unstructured":"Patterson E, Wall R, Fitzgerald GF, et al. Health implications of high dietary omega-6 polyunsaturated fatty acids. J Nutr Metab. 2012;2012:539426.","journal-title":"J Nutr Metab"},{"key":"34_CR12","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.3390\/nu10101561","volume":"10","author":"E Sokola-Wysoczanska","year":"2018","unstructured":"Sokola-Wysoczanska E, Wysoczanski T, Wagner J, et al. Polyunsaturated fatty acids and their potential therapeutic role in cardiovascular system disorders-a review. Nutrients. 2018;10:1561.","journal-title":"Nutrients"},{"key":"34_CR13","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.preteyeres.2018.04.006","volume":"67","author":"EM van Leeuwen","year":"2018","unstructured":"van Leeuwen EM, Emri E, Merle BMJ, et al. A new perspective on lipid research in age-related macular degeneration. Prog Retin Eye Res. 2018;67:56\u201386.","journal-title":"Prog Retin Eye Res"}],"container-title":["Advances in Experimental Medicine and Biology","Retinal Degenerative Diseases XX"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-031-76550-6_34","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T20:46:47Z","timestamp":1739220407000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-031-76550-6_34"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"ISBN":["9783031765490","9783031765506"],"references-count":13,"URL":"https:\/\/doi.org\/10.1007\/978-3-031-76550-6_34","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"11 February 2025","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}},{"value":"IWAAL","order":1,"name":"conference_acronym","label":"Conference Acronym","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"International Workshop on Ambient Assisted Living","order":2,"name":"conference_name","label":"Conference Name","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Torremolinos","order":3,"name":"conference_city","label":"Conference City","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Spain","order":4,"name":"conference_country","label":"Conference Country","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"2011","order":5,"name":"conference_year","label":"Conference Year","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"8 June 2011","order":7,"name":"conference_start_date","label":"Conference Start Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"10 June 2011","order":8,"name":"conference_end_date","label":"Conference End Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"3","order":9,"name":"conference_number","label":"Conference Number","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"7215","order":10,"name":"conference_id","label":"Conference ID","group":{"name":"ConferenceInfo","label":"Conference Information"}}]}}