{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T12:26:59Z","timestamp":1788265619755,"version":"build-2803163510"},"publisher-location":"Cham","reference-count":24,"publisher":"Springer Nature Switzerland","isbn-type":[{"value":"9783031765490","type":"print"},{"value":"9783031765506","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"DOI":"10.1007\/978-3-031-76550-6_36","type":"book-chapter","created":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T20:47:36Z","timestamp":1739220456000},"page":"219-223","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Proposing\u00a0Zebrafish as a Model for Stargardt Disease"],"prefix":"10.1007","author":[{"given":"Qi","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison L.","family":"Reynolds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,2,11]]},"reference":[{"issue":"4","key":"36_CR1","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1002\/dvdy.1188","volume":"222","author":"J Bilotta","year":"2001","unstructured":"Bilotta J, Saszik S, Sutherland SE. Rod contributions to the electroretinogram of the dark-adapted developing zebrafish. Dev Dyn. 2001;222(4):564\u201370.","journal-title":"Dev Dyn"},{"key":"36_CR2","doi-asserted-by":"publisher","first-page":"2448","DOI":"10.1038\/nprot.2006.255","volume":"1","author":"SE Brockerhoff","year":"2006","unstructured":"Brockerhoff SE. Measuring the optokinetic response of zebrafish larvae. Nat Protoc. 2006;1:2448\u201351.","journal-title":"Nat Protoc"},{"key":"36_CR3","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1038\/eye.2014.19","volume":"28","author":"J Chhetri","year":"2014","unstructured":"Chhetri J, Jacobson G, Gueven N. Zebrafish \u2013 on the move towards ophthalmological research. Eye. 2014;28:367\u201380.","journal-title":"Eye"},{"key":"36_CR4","first-page":"1506","volume":"61","author":"RF Collery","year":"2020","unstructured":"Collery RF. Inactivation of zebrafish abca4 orthologs to generate a Stargardt disease model. Invest Ophthalmol Vis Sci. 2020;61:1506.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"36_CR04","doi-asserted-by":"crossref","unstructured":"Conley SM, Cai X, Makkia R, Wu Y, Sparrow JR, Naash MI (2012) Increased cone sensitivity to ABCA4 deficiency provides insight into macular vision loss in Stargardt\u2019s dystrophy. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822(7):1169\u20131179.","DOI":"10.1016\/j.bbadis.2011.10.007"},{"key":"36_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2020.100861","volume":"79","author":"FP Cremers","year":"2020","unstructured":"Cremers FP, Lee W, Collin RW, et al. Clinical spectrum, genetic complexity and therapeutic approaches for retinal disease caused by ABCA4 mutations. Prog Retin Eye Res. 2020;79:100861.","journal-title":"Prog Retin Eye Res"},{"key":"36_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.vascn.2013.09.002","volume":"69","author":"S Deeti","year":"2014","unstructured":"Deeti S, O\u2019Farrell S, Kennedy BN. Early safety assessment of human oculotoxic drugs using the zebrafish visualmotor response. J Pharmacol Toxicol Methods. 2014;69:1\u20138.","journal-title":"J Pharmacol Toxicol Methods"},{"issue":"1075\u20131088","key":"36_CR7","volume":"155","author":"K Fujinami","year":"2013","unstructured":"Fujinami K, Lois N, Davidson AE, et al. A longitudinal study of Stargardt disease: clinical and electrophysiologic assessment, progression, and genotype correlations. Am J Ophthalmol. 2013;155(1075\u20131088):e1013.","journal-title":"Am J Ophthalmol"},{"key":"36_CR8","doi-asserted-by":"publisher","first-page":"9669","DOI":"10.1523\/JNEUROSCI.2414-05.2005","volume":"25","author":"H Hofer","year":"2005","unstructured":"Hofer H, Carroll J, Neitz J, et al. Organization of the human trichromatic cone mosaic. J Neurosci. 2005;25:9669\u201379.","journal-title":"J Neurosci"},{"key":"36_CR9","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1038\/nature12111","volume":"496","author":"K Howe","year":"2013","unstructured":"Howe K, Clark MD, Torroja CF, et al. The zebrafish reference genome sequence and its relationship to the human genome. Nature. 2013;496:498\u2013503.","journal-title":"Nature"},{"key":"36_CR10","doi-asserted-by":"crossref","unstructured":"Kroll F, Powell GT, Ghosh M, et al. A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes. Elife. 2021:10e59683.","DOI":"10.7554\/eLife.59683"},{"key":"36_CR11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1007873","volume":"15","author":"S M\u00e4kel\u00e4inen","year":"2019","unstructured":"M\u00e4kel\u00e4inen S, G\u00f2dia M, Hellsand M, et al. An ABCA4 loss-of-function mutation causes a canine form of Stargardt disease. PLoS Genet. 2019;15:e1007873.","journal-title":"PLoS Genet"},{"key":"36_CR12","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2021.101036","volume":"89","author":"RS Molday","year":"2022","unstructured":"Molday RS, Garces FA, Scortecci JF, et al. Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration. Prog Retin Eye Res. 2022;89:101036.","journal-title":"Prog Retin Eye Res"},{"key":"36_CR13","first-page":"2518","volume":"14","author":"FM Mowat","year":"2008","unstructured":"Mowat FM, Petersen-Jones SM, Williamson H, et al. Topographical characterization of cone photoreceptors and the area centralis of the canine retina. Mol Vis. 2008;14:2518\u201327.","journal-title":"Mol Vis"},{"key":"36_CR14","volume-title":"Fish physiology","author":"SC Neuhauss","year":"2010","unstructured":"Neuhauss SC. Zebrafish vision: structure and function of the zebrafish visual system. In: Fish physiology. Elsevier; 2010."},{"key":"36_CR15","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1002\/cne.24354","volume":"526","author":"NC Noel","year":"2018","unstructured":"Noel NC, Allison WT. Connectivity of cone photoreceptor telodendria in the zebrafish retina. J Comp Neurol. 2018;526:609\u201325.","journal-title":"J Comp Neurol"},{"key":"36_CR16","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2022.101096","volume":"91","author":"NCL Noel","year":"2022","unstructured":"Noel NCL, Allison WT, MacDonald IM, et al. Zebrafish and inherited photoreceptor disease: models and insights. Prog Retin Eye Res. 2022;91:101096.","journal-title":"Prog Retin Eye Res"},{"key":"36_CR17","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1007\/s00417-015-3142-8","volume":"254","author":"K N\u00f5upuu","year":"2016","unstructured":"N\u00f5upuu K, Lee W, Zernant J, et al. Recessive Stargardt disease phenocopying hydroxychloroquine retinopathy. Graefes Arch Clin Exp Ophthalmol. 2016;254:865\u201372.","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"36_CR18","doi-asserted-by":"publisher","first-page":"3821","DOI":"10.1167\/iovs.07-1470","volume":"49","author":"RA Radu","year":"2008","unstructured":"Radu RA, Yuan Q, Hu J, et al. Accelerated accumulation of lipofuscin pigments in the RPE of a mouse model for ABCA4-mediated retinal dystrophies following Vitamin A supplementation. Invest Ophthamol Vis Sci. 2008;49:3821\u20139.","journal-title":"Invest Ophthamol Vis Sci"},{"key":"36_CR19","doi-asserted-by":"publisher","first-page":"1881","DOI":"10.1021\/cr960141c","volume":"101","author":"RR Rando","year":"2001","unstructured":"Rando RR. The biochemistry of the visual cycle. Chem Rev. 2001;101:1881\u201396.","journal-title":"Chem Rev"},{"key":"36_CR20","doi-asserted-by":"publisher","first-page":"6482","DOI":"10.1074\/jbc.RA119.011374","volume":"295","author":"R Ward","year":"2020","unstructured":"Ward R, Kaylor JJ, Cobice DF, et al. Non-photopic and photopic visual cycles differentially regulate immediate, early, and late phases of cone photoreceptor-mediated vision. J Biol Chem. 2020;295:6482\u201397.","journal-title":"J Biol Chem"},{"key":"36_CR21","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/S0092-8674(00)80602-9","volume":"98","author":"J Weng","year":"1999","unstructured":"Weng J, Mata NL, Azarian SM, et al. Insights into the function of Rim protein in photoreceptors and etiology of Stargardt\u2019s disease from the phenotype in abcr knockout mice. Cell. 1999;98:13\u201323.","journal-title":"Cell"},{"key":"36_CR22","doi-asserted-by":"publisher","first-page":"320","DOI":"10.1016\/j.neuron.2020.04.021","volume":"107","author":"T Yoshimatsu","year":"2020","unstructured":"Yoshimatsu T, Schr\u00f6der C, Nevala NE, et al. Fovea-like photoreceptor specializations underlie single UV cone-driven prey-capture behavior in zebrafish. Neuron. 2020;107:320\u2013337.e326.","journal-title":"Neuron"},{"key":"36_CR23","doi-asserted-by":"publisher","first-page":"1569","DOI":"10.1007\/s00424-021-02528-z","volume":"479","author":"J Zang","year":"2021","unstructured":"Zang J, Neuhauss SC. Biochemistry and physiology of zebrafish photoreceptors. Pflugers Arch. 2021;479:1569\u201385.","journal-title":"Pflugers Arch"}],"container-title":["Advances in Experimental Medicine and Biology","Retinal Degenerative Diseases XX"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-031-76550-6_36","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T20:47:38Z","timestamp":1739220458000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-031-76550-6_36"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"ISBN":["9783031765490","9783031765506"],"references-count":24,"URL":"https:\/\/doi.org\/10.1007\/978-3-031-76550-6_36","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"11 February 2025","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}},{"value":"IWAAL","order":1,"name":"conference_acronym","label":"Conference Acronym","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"International Workshop on Ambient Assisted Living","order":2,"name":"conference_name","label":"Conference Name","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Torremolinos","order":3,"name":"conference_city","label":"Conference City","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Spain","order":4,"name":"conference_country","label":"Conference Country","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"2011","order":5,"name":"conference_year","label":"Conference Year","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"8 June 2011","order":7,"name":"conference_start_date","label":"Conference Start Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"10 June 2011","order":8,"name":"conference_end_date","label":"Conference End Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"3","order":9,"name":"conference_number","label":"Conference Number","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"7215","order":10,"name":"conference_id","label":"Conference ID","group":{"name":"ConferenceInfo","label":"Conference Information"}}]}}