{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T14:24:15Z","timestamp":1786371855728,"version":"build-2736575974"},"publisher-location":"Cham","reference-count":216,"publisher":"Springer Nature Switzerland","isbn-type":[{"value":"9783031829895","type":"print"},{"value":"9783031829901","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"DOI":"10.1007\/978-3-031-82990-1_12","type":"book-chapter","created":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T15:48:00Z","timestamp":1745941680000},"page":"273-303","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Proteostasis as a Sentry for Sperm Quality and Male Fertility"],"prefix":"10.1007","author":[{"given":"Peter","family":"Sutovsky","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Zelenkova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavla","family":"Postlerova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michal","family":"Zigo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,30]]},"reference":[{"key":"12_CR1","first-page":"1050","volume-title":"CreateSpace Independent Publishing Platform","author":"KL Harris","year":"2014","unstructured":"Harris, K.L., Caskey-Sigety, L.: The medieval vagina: an historical and hysterical look at all things vaginal during the middle ages. In: CreateSpace Independent Publishing Platform, pp. 1050\u20131097 (2014)"},{"key":"12_CR2","volume-title":"The People\u2019s Common Sense Medical Adviser in Plain English or, Medicine Simplified","author":"RV Pierce","year":"1909","unstructured":"Pierce, R.V.: The People\u2019s Common Sense Medical Adviser in Plain English or, Medicine Simplified. World Dispensary Printing Office and Bindery, Buffalo, NY (1909)"},{"key":"12_CR3","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.fertnstert.2017.11.005","volume":"109","author":"BM Hanson","year":"2018","unstructured":"Hanson, B.M., Eisenberg, M.L., Hotaling, J.M.: Male infertility: a biomarker of individual and familial cancer risk. Fertil. Steril. 109, 6\u201319 (2018)","journal-title":"Fertil. Steril."},{"key":"12_CR4","doi-asserted-by":"publisher","first-page":"355","DOI":"10.4111\/icu.2020.61.4.355","volume":"61","author":"F Del Giudice","year":"2020","unstructured":"Del Giudice, F., Kasman, A.M., Ferro, M., Sciarra, A., De Berardinis, E., Belladelli, F., Salonia, A., Eisenberg, M.L.: Clinical correlation among male infertility and overall male health: a systematic review of the literature. Investig. Clin. Urol. 61, 355\u2013371 (2020)","journal-title":"Investig. Clin. Urol."},{"key":"12_CR5","volume-title":"Brave New World","author":"A Huxley","year":"1932","unstructured":"Huxley, A.: Brave New World. Chatto & Windus, London, UK (1932)"},{"key":"12_CR6","volume-title":"2021 Assisted Reproductive Technology Fertility Clinic and National Summary Report","author":"Center for Disease Control","year":"2023","unstructured":"Center for Disease Control: 2021 Assisted Reproductive Technology Fertility Clinic and National Summary Report (2023)"},{"key":"12_CR7","doi-asserted-by":"publisher","first-page":"11","DOI":"10.3390\/cells11061058","volume":"11","author":"Y Xiong","year":"2022","unstructured":"Xiong, Y., Yu, C., Zhang, Q.: Ubiquitin-proteasome system-regulated protein degradation in spermatogenesis. Cells. 11, 11 (2022)","journal-title":"Cells"},{"key":"12_CR8","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1530\/REP-18-0413","volume":"157","author":"M Zigo","year":"2019","unstructured":"Zigo, M., Jonakova, V., Manaskova-Postlerova, P., Kerns, K., Sutovsky, P.: Ubiquitin-proteasome system participates in the de-aggregation of spermadhesin and DQH protein during boar sperm capacitation. Reproduction. 157, 283\u2013295 (2019)","journal-title":"Reproduction"},{"key":"12_CR9","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1016\/j.cell.2017.04.034","volume":"169","author":"LT Gou","year":"2017","unstructured":"Gou, L.T., Kang, J.Y., Dai, P., Wang, X., Li, F., Zhao, S., Zhang, M., Hua, M.M., Lu, Y., Zhu, Y., Li, Z., Chen, H., et al.: Ubiquitination-deficient mutations in human Piwi cause male infertility by impairing histone-to-protamine exchange during spermiogenesis. Cell. 169, 1090\u20131104 e1013 (2017)","journal-title":"Cell"},{"key":"12_CR10","doi-asserted-by":"publisher","first-page":"13165","DOI":"10.1074\/jbc.273.21.13165","volume":"273","author":"HY Chen","year":"1998","unstructured":"Chen, H.Y., Sun, J.M., Zhang, Y., Davie, J.R., Meistrich, M.L.: Ubiquitination of histone H3 in elongating spermatids of rat testes. J. Biol. Chem. 273, 13165\u201313169 (1998)","journal-title":"J. Biol. Chem."},{"key":"12_CR11","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1095\/biolreprod.104.030866","volume":"72","author":"G Berruti","year":"2005","unstructured":"Berruti, G., Martegani, E.: The deubiquitinating enzyme mUBPy interacts with the sperm-specific molecular chaperone MSJ-1: the relation with the proteasome, acrosome, and centrosome in mouse male germ cells. Biol. Reprod. 72, 14\u201321 (2005)","journal-title":"Biol. Reprod."},{"key":"12_CR12","doi-asserted-by":"publisher","first-page":"9202","DOI":"10.1038\/s41598-018-27379-0","volume":"8","author":"A Ali","year":"2018","unstructured":"Ali, A., Mistry, B.V., Ahmed, H.A., Abdulla, R., Amer, H.A., Prince, A., Alazami, A.M., Alkuraya, F.S., Assiri, A.: Deletion of DDB1- and CUL4- associated factor-17 (Dcaf17) gene causes spermatogenesis defects and male infertility in mice. Sci. Rep. 8, 9202 (2018)","journal-title":"Sci. Rep."},{"key":"12_CR13","doi-asserted-by":"publisher","first-page":"6923","DOI":"10.1074\/jbc.M115.699660","volume":"291","author":"Y Yin","year":"2016","unstructured":"Yin, Y., Liu, L., Yang, C., Lin, C., Veith, G.M., Wang, C., Sutovsky, P., Zhou, P., Ma, L.: Cell autonomous and nonautonomous function of CUL4B in mouse spermatogenesis. J. Biol. Chem. 291, 6923\u20136935 (2016)","journal-title":"J. Biol. Chem."},{"key":"12_CR14","doi-asserted-by":"publisher","first-page":"554","DOI":"10.4103\/1008-682X.153847","volume":"17","author":"P Sutovsky","year":"2015","unstructured":"Sutovsky, P., Aarabi, M., Miranda-Vizuete, A., Oko, R.: Negative biomarker based male fertility evaluation: sperm phenotypes associated with molecular-level anomalies. Asian J. Androl. 17, 554\u2013560 (2015)","journal-title":"Asian J. Androl."},{"key":"12_CR15","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1007\/978-3-319-16892-0_4","volume-title":"Screening for the Single Euploid Embryo \u2013 Molecular Genetics in Reproductive Medicine","author":"P Ahlering","year":"2015","unstructured":"Ahlering, P., Sutovsky, P.: Biomarker-based flow-cytometric semen analysis for male infertility diagnostics and clinical decision making in ART. In: Sills, E.S. (ed.) Screening for the Single Euploid Embryo \u2013 Molecular Genetics in Reproductive Medicine, pp. 33\u201351. Springer (2015)"},{"key":"12_CR16","first-page":"5","volume":"204","author":"K Toshimori","year":"2009","unstructured":"Toshimori, K.: Dynamics of the mammalian sperm head: modifications and maturation events from spermatogenesis to egg activation. Adv. Anat. Embryol. Cell Biol. 204, 5\u201394 (2009)","journal-title":"Adv. Anat. Embryol. Cell Biol."},{"key":"12_CR17","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1016\/j.theriogenology.2005.05.005","volume":"64","author":"PJ Chenoweth","year":"2005","unstructured":"Chenoweth, P.J.: Genetic sperm defects. Theriogenology. 64, 457\u2013468 (2005)","journal-title":"Theriogenology"},{"key":"12_CR18","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/S0022-5320(80)90099-4","volume":"71","author":"JL Courtens","year":"1980","unstructured":"Courtens, J.L., Amir, D., Durand, J.: Abnormal spermiogenesis in bulls treated with ethylene dibromide: an ultrastructural and ultracytochemical study. J. Ultrastruct. Res. 71, 103\u2013115 (1980)","journal-title":"J. Ultrastruct. Res."},{"key":"12_CR19","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/0093-691X(78)90147-4","volume":"9","author":"GH Coulter","year":"1978","unstructured":"Coulter, G.H., Oko, R.J., Costerton, J.W.: Incidence and ultrastructure of \u201ccrater\u201d defect of bovine spermatozoa. Theriogenology. 9, 165\u2013173 (1978)","journal-title":"Theriogenology"},{"key":"12_CR20","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1007\/978-3-030-89340-8_15","volume":"1358","author":"LE Hamilton","year":"2022","unstructured":"Hamilton, L.E., Oko, R., Miranda-Vizuete, A., Sutovsky, P.: Sperm redox system equilibrium: implications for fertilization and male fertility. Adv. Exp. Med. Biol. 1358, 345\u2013367 (2022)","journal-title":"Adv. Exp. Med. Biol."},{"key":"12_CR21","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1089\/152308604771978327","volume":"6","author":"A Miranda-Vizuete","year":"2004","unstructured":"Miranda-Vizuete, A., Sadek, C.M., Jimenez, A., Krause, W.J., Sutovsky, P., Oko, R.: The mammalian testis-specific thioredoxin system. Antioxid. Redox Signal. 6, 25\u201340 (2004)","journal-title":"Antioxid. Redox Signal."},{"key":"12_CR22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061000","volume":"8","author":"C Buckman","year":"2013","unstructured":"Buckman, C., Ozanon, C., Qiu, J., Sutovsky, M., Carafa, J.A., Rawe, V.Y., Manandhar, G., Miranda-Vizuete, A., Sutovsky, P.: Semen levels of spermatid-specific thioredoxin-3 correlate with pregnancy rates in ART couples. PLoS One. 8, e61000 (2013)","journal-title":"PLoS One"},{"key":"12_CR23","doi-asserted-by":"publisher","first-page":"34971","DOI":"10.1074\/jbc.M404192200","volume":"279","author":"A Jimenez","year":"2004","unstructured":"Jimenez, A., Zu, W., Rawe, V.Y., Pelto-Huikko, M., Flickinger, C.J., Sutovsky, P., Gustafsson, J.A., Oko, R., Miranda-Vizuete, A.: Spermatocyte\/spermatid-specific thioredoxin-3, a novel Golgi apparatus-associated thioredoxin, is a specific marker of aberrant spermatogenesis. J. Biol. Chem. 279, 34971\u201334982 (2004)","journal-title":"J. Biol. Chem."},{"key":"12_CR24","doi-asserted-by":"publisher","first-page":"2119","DOI":"10.1093\/humrep\/17.8.2119","volume":"17","author":"VY Rawe","year":"2002","unstructured":"Rawe, V.Y., Olmedo, S.B., Benmusa, A., Shiigi, S.M., Chemes, H.E., Sutovsky, P.: Sperm ubiquitination in patients with dysplasia of the fibrous sheath. Hum. Reprod. 17, 2119\u20132127 (2002)","journal-title":"Hum. Reprod."},{"key":"12_CR25","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1093\/humrep\/deh131","volume":"19","author":"P Sutovsky","year":"2004","unstructured":"Sutovsky, P., Hauser, R., Sutovsky, M.: Increased levels of sperm ubiquitin correlate with semen quality in men from an andrology laboratory clinic population. Hum. Reprod. 19, 628\u2013638 (2004)","journal-title":"Hum. Reprod."},{"key":"12_CR26","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1093\/humrep\/16.2.250","volume":"16","author":"P Sutovsky","year":"2001","unstructured":"Sutovsky, P., Terada, Y., Schatten, G.: Ubiquitin-based sperm assay for the diagnosis of male factor infertility. Hum. Reprod. 16, 250\u2013258 (2001)","journal-title":"Hum. Reprod."},{"key":"12_CR27","doi-asserted-by":"publisher","first-page":"2271","DOI":"10.1093\/humrep\/dei013","volume":"20","author":"C Ozanon","year":"2005","unstructured":"Ozanon, C., Chouteau, J., Sutovsky, P.: Clinical adaptation of the sperm ubuquitin tag immunoassay (SUTI): relationship of sperm ubiquitylation with sperm quality in gradient-purified semen samples from 93 men from a general infertility clinic population. Hum. Reprod. 20, 2271\u20132278 (2005)","journal-title":"Hum. Reprod."},{"key":"12_CR28","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1111\/j.1439-0272.2012.01330.x","volume":"45","author":"M Eskandari-Shahraki","year":"2013","unstructured":"Eskandari-Shahraki, M., Tavalaee, M., Deemeh, M.R., Jelodar, G.A., Nasr-Esfahani, M.H.: Proper ubiquitination effect on the fertilisation outcome post-ICSI. Andrologia. 45, 204\u2013210 (2013)","journal-title":"Andrologia"},{"key":"12_CR29","doi-asserted-by":"publisher","first-page":"1665","DOI":"10.1242\/jcs.114.9.1665","volume":"114","author":"P Sutovsky","year":"2001","unstructured":"Sutovsky, P., Moreno, R., Ramalho-Santos, J., Dominko, T., Thompson, W.E., Schatten, G.: A putative, ubiquitin-dependent mechanism for the recognition and elimination of defective spermatozoa in the mammalian epididymis. J. Cell Sci. 114, 1665\u20131675 (2001)","journal-title":"J. Cell Sci."},{"key":"12_CR30","doi-asserted-by":"publisher","first-page":"51266","DOI":"10.1074\/jbc.M410485200","volume":"279","author":"GE Olson","year":"2004","unstructured":"Olson, G.E., Winfrey, V.P., NagDas, S.K., Melner, M.H.: Region-specific expression and secretion of the fibrinogen-related protein, fgl2, by epithelial cells of the hamster epididymis and its role in disposal of defective spermatozoa. J. Biol. Chem. 279, 51266\u201351274 (2004)","journal-title":"J. Biol. Chem."},{"key":"12_CR31","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1530\/REP-10-0493","volume":"141","author":"N Da Silva","year":"2011","unstructured":"Da Silva, N., Cortez-Retamozo, V., Reinecker, H.C., Wildgruber, M., Hill, E., Brown, D., Swirski, F.K., Pittet, M.J., Breton, S.: A dense network of dendritic cells populates the murine epididymis. Reproduction. 141, 653\u2013663 (2011)","journal-title":"Reproduction"},{"key":"12_CR32","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1007\/s00441-015-2289-2","volume":"363","author":"G Plante","year":"2016","unstructured":"Plante, G., Prud'homme, B., Fan, J., Lafleur, M., Manjunath, P.: Evolution and function of mammalian binder of sperm proteins. Cell Tissue Res. 363, 105\u2013127 (2016)","journal-title":"Cell Tissue Res."},{"key":"12_CR33","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1095\/biolreprod.114.121897","volume":"91","author":"JF Odhiambo","year":"2014","unstructured":"Odhiambo, J.F., DeJarnette, J.M., Geary, T.W., Kennedy, C.E., Suarez, S.S., Sutovsky, M., Sutovsky, P.: Increased conception rates in beef cattle inseminated with nanopurified bull semen. Biol. Reprod. 91, 97 (2014)","journal-title":"Biol. Reprod."},{"key":"12_CR34","doi-asserted-by":"crossref","unstructured":"Diaz-Miranda, E.A., Hamilton, L.E., Zigo, M., Fallon, L., Ortega, M.S., D'Avila Assumpcao, M.E.O., Guimaraes, J.D., Sutovsky, P.: Regional abundances of binder of sperm (BSP) proteins are negatively associated with the quality of frozen-thawed bovine spermatozoa. Reproduction. 167 (2024)","DOI":"10.1530\/REP-23-0305"},{"key":"12_CR35","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1111\/j.1439-0272.1998.tb01163.x","volume":"30","author":"E Topfer-Petersen","year":"1998","unstructured":"Topfer-Petersen, E., Romero, A., Varela, P.F., Ekhlasi-Hundrieser, M., Dostalova, Z., Sanz, L., Calvete, J.J.: Spermadhesins: a new protein family. Facts, hypotheses and perspectives. Andrologia. 30, 217\u2013224 (1998)","journal-title":"Andrologia"},{"key":"12_CR36","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/0014-5793(94)00362-9","volume":"344","author":"R Einspanier","year":"1994","unstructured":"Einspanier, R., Krause, I., Calvete, J.J., T\u00f6fper-Petersen, E., Klostermeyer, H., Karg, H.: Bovine seminal plasma aSFP: localization of disulfide bridges and detection of three different isoelectric forms. FEBS Lett. 344, 61\u201364 (1994)","journal-title":"FEBS Lett."},{"key":"12_CR37","doi-asserted-by":"publisher","first-page":"6175","DOI":"10.1046\/j.1432-1327.2000.01698.x","volume":"267","author":"G Tedeschi","year":"2000","unstructured":"Tedeschi, G., Oungre, E., Mortarino, M., Negri, A., Maffeo, G., Ronchi, S.: Purification and primary structure of a new bovine spermadhesin. Eur. J. Biochem. 267, 6175\u20136179 (2000)","journal-title":"Eur. J. Biochem."},{"key":"12_CR38","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1111\/j.1432-1033.1996.0636r.x","volume":"242","author":"M Reinert","year":"1996","unstructured":"Reinert, M., Calvete, J.J., Sanz, L., Mann, K., T\u00f6pfer-Petersen, E.: Primary structure of stallion seminal plasma protein HSP-7, a zona-pellucida-binding protein of the spermadhesin family. Eur. J. Biochem. 242, 636\u2013640 (1996)","journal-title":"Eur. J. Biochem."},{"key":"12_CR39","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1002\/mrd.20310","volume":"71","author":"A Bergeron","year":"2005","unstructured":"Bergeron, A., Villemure, M., Lazure, C., Manjunath, P.: Isolation and characterization of the major proteins of ram seminal plasma. Mol. Reprod. Dev. 71, 461\u2013470 (2005)","journal-title":"Mol. Reprod. Dev."},{"key":"12_CR40","doi-asserted-by":"publisher","first-page":"331","DOI":"10.2174\/0929866023408670","volume":"9","author":"DI Teixeira","year":"2002","unstructured":"Teixeira, D.I., Cavada, B.S., Sampaio, A.H., Havt, A., Bloch Jr., C., Prates, M.V., Moreno, F.B., Santos, E.A., Gadelha, C.A., Gadelha, T.S., Cris\u00f3stomo, F.S., Freitas, V.J.: Isolation and partial characterisation of a protein from buck seminal plasma (Capra hircus), homologous to spermadhesins. Protein Pept. Lett. 9, 331\u2013335 (2002)","journal-title":"Protein Pept. Lett."},{"key":"12_CR41","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/S0165-0378(01)00072-9","volume":"51","author":"M Kraus","year":"2001","unstructured":"Kraus, M., Tich\u00e1, M., Jon\u00e1kov\u00e1, V.: Heparin-binding proteins of human seminal plasma homologous with boar spermadhesins. J. Reprod. Immunol. 51, 131\u2013144 (2001)","journal-title":"J. Reprod. Immunol."},{"key":"12_CR42","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.jri.2004.10.001","volume":"65","author":"M Kraus","year":"2005","unstructured":"Kraus, M., Tich\u00e1, M., Zelezn\u00e1, B., Peknicov\u00e1, J., Jon\u00e1kov\u00e1, V.: Characterization of human seminal plasma proteins homologous to boar AQN spermadhesins. J. Reprod. Immunol. 65, 33\u201346 (2005)","journal-title":"J. Reprod. Immunol."},{"key":"12_CR43","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1002\/(SICI)1098-2795(200006)56:2+<275::AID-MRD13>3.0.CO;2-G","volume":"56","author":"V Jonakova","year":"2000","unstructured":"Jonakova, V., Manaskova, P., Kraus, M., Liberda, J., Ticha, M.: Sperm surface proteins in mammalian fertilization. Mol. Reprod. Dev. 56, 275\u2013277 (2000)","journal-title":"Mol. Reprod. Dev."},{"key":"12_CR44","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/j.jri.2006.01.008","volume":"71","author":"J Liberda","year":"2006","unstructured":"Liberda, J., Manaskova, P., Prelovska, L., Ticha, M., Jonakova, V.: Saccharide-mediated interactions of boar sperm surface proteins with components of the porcine oviduct. J. Reprod. Immunol. 71, 112\u2013125 (2006)","journal-title":"J. Reprod. Immunol."},{"key":"12_CR45","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1016\/j.theriogenology.2009.07.005","volume":"73","author":"R Talevi","year":"2010","unstructured":"Talevi, R., Gualtieri, R.: Molecules involved in sperm-oviduct adhesion and release. Theriogenology. 73, 796\u2013801 (2010)","journal-title":"Theriogenology"},{"key":"12_CR46","doi-asserted-by":"publisher","first-page":"188","DOI":"10.2164\/jandrol.109.007583","volume":"31","author":"S Novak","year":"2010","unstructured":"Novak, S., Ruiz-S\u00e1nchez, A., Dixon, W.T., Foxcroft, G.R., Dyck, M.K.: Seminal plasma proteins as potential markers of relative fertility in boars. J. Androl. 31, 188\u2013200 (2010)","journal-title":"J. Androl."},{"key":"12_CR47","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.jri.2009.10.007","volume":"84","author":"H Rodriguez-Martinez","year":"2010","unstructured":"Rodriguez-Martinez, H., Saravia, F., Wallgren, M., Martinez, E.A., Sanz, L., Roca, J., Vazquez, J.M., Calvete, J.J.: Spermadhesin PSP-I\/PSP-II heterodimer induces migration of polymorphonuclear neutrophils into the uterine cavity of the sow. J. Reprod. Immunol. 84, 57\u201365 (2010)","journal-title":"J. Reprod. Immunol."},{"key":"12_CR48","doi-asserted-by":"publisher","first-page":"1230","DOI":"10.1074\/mcp.M114.045369","volume":"14","author":"WS Kwon","year":"2015","unstructured":"Kwon, W.S., Rahman, M.S., Lee, J.S., Yoon, S.J., Park, Y.J., Pang, M.G.: Discovery of predictive biomarkers for litter size in boar spermatozoa. Mol. Cell. Proteomics. 14, 1230\u20131240 (2015)","journal-title":"Mol. Cell. Proteomics"},{"key":"12_CR49","doi-asserted-by":"publisher","first-page":"15654","DOI":"10.1038\/srep15654","volume":"5","author":"WS Kwon","year":"2015","unstructured":"Kwon, W.S., Rahman, M.S., Ryu, D.Y., Park, Y.J., Pang, M.G.: Increased male fertility using fertility-related biomarkers. Sci. Rep. 5, 15654 (2015)","journal-title":"Sci. Rep."},{"key":"12_CR50","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1021\/acs.jproteome.7b00728","volume":"17","author":"C P\u00e9rez-Pati\u00f1o","year":"2018","unstructured":"P\u00e9rez-Pati\u00f1o, C., Parrilla, I., Barranco, I., Vergara-Barber\u00e1n, M., Sim\u00f3-Alfonso, E.F., Herrero-Mart\u00ednez, J.M., Rodriguez-Mart\u00ednez, H., Mart\u00ednez, E.A., Roca, J.: New in-depth analytical approach of the porcine seminal plasma proteome reveals potential fertility biomarkers. J. Proteome Res. 17, 1065\u20131076 (2018)","journal-title":"J. Proteome Res."},{"key":"12_CR51","doi-asserted-by":"publisher","first-page":"1032","DOI":"10.1111\/andr.12404","volume":"5","author":"L Somashekar","year":"2017","unstructured":"Somashekar, L., Selvaraju, S., Parthipan, S., Patil, S.K., Binsila, B.K., Venkataswamy, M.M., Karthik Bhat, S., Ravindra, J.P.: Comparative sperm protein profiling in bulls differing in fertility and identification of phosphatidylethanolamine-binding protein 4, a potential fertility marker. Andrology. 5, 1032\u20131051 (2017)","journal-title":"Andrology"},{"key":"12_CR52","doi-asserted-by":"crossref","unstructured":"Ram\u00edrez-L\u00f3pez, C.J., Barros, E., Vidigal, P.M.P., Silva Okano, D., Duarte Rodrigues, J.N., Lopes Gomes, L., Montes-Vergara, J.C., Petro Hernandez, V.G., Baracat-Pereira, M.C., Guimar\u00e3es, S.E.F., Guimar\u00e3es, J.D.: Relative abundance of Spermadhesin-1 in the seminal plasma of young Nellore bulls is in agreement with reproductive parameters. Vet. Sci. 10 (2023)","DOI":"10.3390\/vetsci10100610"},{"key":"12_CR53","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1095\/biolreprod.103.016527","volume":"69","author":"F Centurion","year":"2003","unstructured":"Centurion, F., Vazquez, J.M., Calvete, J.J., Roca, J., Sanz, L., Parrilla, I., Garcia, E.M., Martinez, E.A.: Influence of porcine spermadhesins on the susceptibility of boar spermatozoa to high dilution. Biol. Reprod. 69, 640\u2013646 (2003)","journal-title":"Biol. Reprod."},{"key":"12_CR54","doi-asserted-by":"publisher","first-page":"766","DOI":"10.2164\/jandrol.106.000539","volume":"27","author":"I Caballero","year":"2006","unstructured":"Caballero, I., V\u00e1zquez, J.M., Garc\u00eda, E.M., Roca, J., Mart\u00ednez, E.A., Calvete, J.J., Sanz, L., Ekwall, H., Rodr\u00edguez-Mart\u00ednez, H.: Immunolocalization and possible functional role of PSP-I\/PSP-II heterodimer in highly extended boar spermatozoa. J. Androl. 27, 766\u2013773 (2006)","journal-title":"J. Androl."},{"key":"12_CR55","doi-asserted-by":"publisher","first-page":"14661","DOI":"10.1038\/s41598-020-71015-9","volume":"10","author":"FP Gomes","year":"2020","unstructured":"Gomes, F.P., Park, R., Viana, A.G., Fernandez-Costa, C., Topper, E., Kaya, A., Memili, E., Yates 3rd, J.R., Moura, A.A.: Protein signatures of seminal plasma from bulls with contrasting frozen-thawed sperm viability. Sci. Rep. 10, 14661 (2020)","journal-title":"Sci. Rep."},{"key":"12_CR56","doi-asserted-by":"crossref","unstructured":"Simonik, O., Bubenickova, F., Tumova, L., Frolikova, M., Sur, V.P., Beran, J., Havlikova, K., Hackerova, L., Spevakova, D., Komrskova, K., Postlerova, P.: Boar sperm cryopreservation improvement using semen extender modification by dextran and pentaisomaltose. Animals (Basel). 12 (2022)","DOI":"10.3390\/ani12070868"},{"key":"12_CR57","doi-asserted-by":"crossref","unstructured":"Bubenickova, F., Postlerova, P., Simonik, O., Sirohi, J., Sichtar, J.: Effect of seminal plasma protein fractions on stallion sperm cryopreservation. Int. J. Mol. Sci. 21 (2020)","DOI":"10.3390\/ijms21176415"},{"key":"12_CR58","doi-asserted-by":"publisher","first-page":"12","DOI":"10.7554\/eLife.85596.3","volume":"12","author":"D Zuidema","year":"2023","unstructured":"Zuidema, D., Jones, A., Song, W.H., Zigo, M., Sutovsky, P.: Identification of candidate mitochondrial inheritance determinants using the mammalian cell-free system. elife. 12, 12 (2023)","journal-title":"elife"},{"key":"12_CR59","doi-asserted-by":"publisher","first-page":"E5261","DOI":"10.1073\/pnas.1605844113","volume":"113","author":"WH Song","year":"2016","unstructured":"Song, W.H., Yi, Y.J., Sutovsky, M., Meyers, S., Sutovsky, P.: Autophagy and ubiquitin-proteasome system contribute to sperm mitophagy after mammalian fertilization. Proc. Natl. Acad. Sci. USA. 113, E5261\u2013E5270 (2016)","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"12_CR60","doi-asserted-by":"publisher","first-page":"9","DOI":"10.3390\/antiox9111033","volume":"9","author":"K Kerns","year":"2020","unstructured":"Kerns, K., Jankovitz, J., Robinson, J., Minton, A., Kuster, C., Sutovsky, P.: Relationship between the length of sperm tail mitochondrial sheath and fertility traits in boars used for artificial insemination. Antioxidants. 9, 9 (2020)","journal-title":"Antioxidants"},{"key":"12_CR61","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1002\/mrd.22309","volume":"81","author":"CE Kennedy","year":"2014","unstructured":"Kennedy, C.E., Krieger, K.B., Sutovsky, M., Xu, W., Vargovic, P., Didion, B.A., Ellersieck, M.R., Hennessy, M.E., Verstegen, J., Oko, R., Sutovsky, P.: Protein expression pattern of PAWP in bull spermatozoa is associated with sperm quality and fertility following artificial insemination. Mol. Reprod. Dev. 81, 436\u2013449 (2014)","journal-title":"Mol. Reprod. Dev."},{"key":"12_CR62","doi-asserted-by":"publisher","first-page":"1258295","DOI":"10.3389\/fvets.2023.1258295","volume":"10","author":"L Fallon","year":"2023","unstructured":"Fallon, L., Diaz-Miranda, E., Hamilton, L.E., Sutovsky, P., Zigo, M., Spencer, T.E., Ortega, M.S.: The development of new biomarkers of spermatozoa quality in cattle. Front. Vet. Sci. 10, 1258295 (2023)","journal-title":"Front. Vet. Sci."},{"key":"12_CR63","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.jprot.2016.08.018","volume":"162","author":"M Jodar","year":"2017","unstructured":"Jodar, M., Soler-Ventura, A., Oliva, R.: Semen proteomics and male infertility. J. Proteome. 162, 125\u2013134 (2017)","journal-title":"J. Proteome"},{"key":"12_CR64","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1093\/humupd\/dmt046","volume":"20","author":"A Amaral","year":"2014","unstructured":"Amaral, A., Castillo, J., Ramalho-Santos, J., Oliva, R.: The combined human sperm proteome: cellular pathways and implications for basic and clinical science. Hum. Reprod. Update. 20, 40\u201362 (2014)","journal-title":"Hum. Reprod. Update"},{"key":"12_CR65","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1111\/andr.13289","volume":"11","author":"N Chhikara","year":"2023","unstructured":"Chhikara, N., Tomar, A.K., Datta, S.K., Yadav, S.: Proteomic changes in human spermatozoa during in vitro capacitation and acrosome reaction in normozoospermia and asthenozoospermia. Andrology. 11, 73\u201385 (2023)","journal-title":"Andrology"},{"key":"12_CR66","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1111\/andr.12627","volume":"8","author":"G Hern\u00e1ndez-Silva","year":"2020","unstructured":"Hern\u00e1ndez-Silva, G., Fabi\u00e1n L\u00f3pez-Araiza, J.E., L\u00f3pez-Torres, A.S., Larrea, F., Torres-Flores, V., Chirinos, M.: Proteomic characterization of human sperm plasma membrane-associated proteins and their role in capacitation. Andrology. 8, 171\u2013180 (2020)","journal-title":"Andrology"},{"key":"12_CR67","doi-asserted-by":"publisher","first-page":"295","DOI":"10.3389\/fcell.2019.00295","volume":"7","author":"J Castillo","year":"2019","unstructured":"Castillo, J., Bogle, O.A., Jodar, M., Torabi, F., Delgado-Due\u00f1as, D., Estanyol, J.M., Ballesc\u00e0, J.L., Miller, D., Oliva, R.: Proteomic changes in human sperm during sequential in vitro capacitation and acrosome reaction. Front. Cell Dev. Biol. 7, 295 (2019)","journal-title":"Front. Cell Dev. Biol."},{"key":"12_CR68","doi-asserted-by":"publisher","first-page":"3377","DOI":"10.1021\/pr900031r","volume":"8","author":"F Secciani","year":"2009","unstructured":"Secciani, F., Bianchi, L., Ermini, L., Cianti, R., Armini, A., La Sala, G.B., Focarelli, R., Bini, L., Rosati, F.: Protein profile of capacitated versus ejaculated human sperm. J. Proteome Res. 8, 3377\u20133389 (2009)","journal-title":"J. Proteome Res."},{"key":"12_CR69","doi-asserted-by":"publisher","first-page":"2651","DOI":"10.1002\/jcp.22615","volume":"226","author":"B Nixon","year":"2011","unstructured":"Nixon, B., Mitchell, L.A., Anderson, A.L., McLaughlin, E.A., O'Bryan, M.K., Aitken, R.J.: Proteomic and functional analysis of human sperm detergent resistant membranes. J. Cell. Physiol. 226, 2651\u20132665 (2011)","journal-title":"J. Cell. Physiol."},{"key":"12_CR70","doi-asserted-by":"publisher","first-page":"2061","DOI":"10.1038\/s41467-018-04523-y","volume":"9","author":"K Kerns","year":"2018","unstructured":"Kerns, K., Zigo, M., Drobnis, E.Z., Sutovsky, M., Sutovsky, P.: Zinc ion flux during mammalian sperm capacitation. Nat. Commun. 9, 2061 (2018)","journal-title":"Nat. Commun."},{"key":"12_CR71","doi-asserted-by":"crossref","unstructured":"Kerns, K., Sharif, M., Zigo, M., Xu, W., Hamilton, L.E., Sutovsky, M., Ellersieck, M., Drobnis, E.Z., Bovin, N., Oko, R., Miller, D., Sutovsky, P.: Sperm cohort-specific zinc signature acquisition and capacitation-induced zinc flux regulate sperm-oviduct and sperm-zona Pellucida interactions. Int. J. Mol. Sci. 21 (2020)","DOI":"10.3390\/ijms21062121"},{"key":"12_CR72","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1038\/s42003-022-03485-8","volume":"5","author":"M Zigo","year":"2022","unstructured":"Zigo, M., Kerns, K., Sen, S., Essien, C., Oko, R., Xu, D., Sutovsky, P.: Zinc is a master-regulator of sperm function associated with binding, motility, and metabolic modulation during porcine sperm capacitation. Commun. Biol. 5, 538 (2022)","journal-title":"Commun. Biol."},{"key":"12_CR73","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1093\/molehr\/gap099","volume":"16","author":"L Bjorndahl","year":"2010","unstructured":"Bjorndahl, L., Kvist, U.: Human sperm chromatin stabilization: a proposed model including zinc bridges. Mol. Hum. Reprod. 16, 23\u201329 (2010)","journal-title":"Mol. Hum. Reprod."},{"key":"12_CR74","doi-asserted-by":"publisher","first-page":"406","DOI":"10.1002\/mrd.10101","volume":"61","author":"P Sutovsky","year":"2002","unstructured":"Sutovsky, P., Neuber, E., Schatten, G.: Ubiquitin-dependent sperm quality control mechanism recognizes spermatozoa with DNA defects as revealed by dual ubiquitin-TUNEL assay. Mol. Reprod. Dev. 61, 406\u2013413 (2002)","journal-title":"Mol. Reprod. Dev."},{"key":"12_CR75","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/j.fertnstert.2006.07.1528","volume":"87","author":"S Varum","year":"2007","unstructured":"Varum, S., Bento, C., Sousa, A.P., Gomes-Santos, C.S., Henriques, P., Almeida-Santos, T., Teodosio, C., Paiva, A., Ramalho-Santos, J.: Characterization of human sperm populations using conventional parameters, surface ubiquitination, and apoptotic markers. Fertil. Steril. 87, 572\u2013583 (2007)","journal-title":"Fertil. Steril."},{"key":"12_CR76","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1080\/19396368.2019.1666435","volume":"66","author":"M Stiavnicka","year":"2020","unstructured":"Stiavnicka, M., Garcia-Alvarez, O., Ulcova-Gallova, Z., Sutovsky, P., Abril-Parreno, L., Dolejsova, M., Rimnacova, H., Moravec, J., Hosek, P., Losan, P., Gold, L., Fenclova, T., et al.: H3K4me2 accompanies chromatin immaturity in human spermatozoa: an epigenetic marker for sperm quality assessment. Syst Biol Reprod Med. 66, 3\u201311 (2020)","journal-title":"Syst Biol Reprod Med"},{"key":"12_CR77","doi-asserted-by":"publisher","first-page":"512","DOI":"10.1016\/j.nbd.2007.01.006","volume":"26","author":"JM Van Raamsdonk","year":"2007","unstructured":"Van Raamsdonk, J.M., Murphy, Z., Selva, D.M., Hamidizadeh, R., Pearson, J., Peters\u00e9n, A., Bj\u00f6rkqvist, M., Muir, C., Mackenzie, I.R., Hammond, G.L., Vogl, A.W., Hayden, M.R., et al.: Testicular degeneration in Huntington disease. Neurobiol. Dis. 26, 512\u2013520 (2007)","journal-title":"Neurobiol. Dis."},{"key":"12_CR78","doi-asserted-by":"publisher","first-page":"47","DOI":"10.3233\/JHD-130001","volume":"2","author":"M Baxa","year":"2013","unstructured":"Baxa, M., Hruska-Plochan, M., Juhas, S., Vodicka, P., Pavlok, A., Juhasova, J., Miyanohara, A., Nejime, T., Klima, J., Macakova, M., Marsala, S., Weiss, A., et al.: A transgenic minipig model of Huntington's disease. J. Huntingtons Dis. 2, 47\u201368 (2013)","journal-title":"J. Huntingtons Dis."},{"key":"12_CR79","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1159\/000475467","volume":"17","author":"J Krizova","year":"2017","unstructured":"Krizova, J., Stufkova, H., Rodinova, M., Macakova, M., Bohuslavova, B., Vidinska, D., Klima, J., Ellederova, Z., Pavlok, A., Howland, D.S., Zeman, J., Motlik, J., et al.: Mitochondrial metabolism in a large-animal model of Huntington disease: the hunt for biomarkers in the spermatozoa of Presymptomatic Minipigs. Neurodegener Dis. 17, 213\u2013226 (2017)","journal-title":"Neurodegener Dis."},{"key":"12_CR80","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1159\/000443665","volume":"16","author":"M Macakova","year":"2016","unstructured":"Macakova, M., Bohuslavova, B., Vochozkova, P., Pavlok, A., Sedlackova, M., Vidinska, D., Vochyanova, K., Liskova, I., Valekova, I., Baxa, M., Ellederova, Z., Klima, J., et al.: Mutated huntingtin causes testicular pathology in transgenic Minipig boars. Neurodegener Dis. 16, 245\u2013259 (2016)","journal-title":"Neurodegener Dis"},{"key":"12_CR81","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1159\/000488592","volume":"18","author":"D Vidinsk\u00e1","year":"2018","unstructured":"Vidinsk\u00e1, D., Vochozkov\u00e1, P., \u0160matl\u00edkov\u00e1, P., Ardan, T., Kl\u00edma, J., Juh\u00e1s, \u0160., Juh\u00e1sov\u00e1, J., Bohuslavov\u00e1, B., Baxa, M., Valekov\u00e1, I., Motl\u00edk, J., Ellederov\u00e1, Z.: Gradual phenotype development in Huntington disease transgenic Minipig model at 24 months of age. Neurodegener Dis. 18, 107\u2013119 (2018)","journal-title":"Neurodegener Dis"},{"key":"12_CR82","first-page":"13","volume":"13","author":"S Chen","year":"2022","unstructured":"Chen, S., Yang, Y., Gao, B., Jia, C., Zhu, F., Meng, Q., Zhang, Z., Zhang, Z., Xu, S.: Comparative proteomics of the Acanthopagrus schlegelii gonad in different sex reversal. Genes (Basel). 13, 13 (2022)","journal-title":"Genes (Basel)"},{"key":"12_CR83","doi-asserted-by":"crossref","unstructured":"Zmudzinska, A., Bromke, M.A., Strzezek, R., Zielinska, M., Olejnik, B., Mogielnicka-Brzozowska, M.: Proteomic analysis of intracellular and membrane-associated fractions of canine (Canis lupus familiaris) epididymal spermatozoa and sperm structure separation. Animals (Basel). 12 (2022)","DOI":"10.3390\/ani12060772"},{"key":"12_CR84","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.theriogenology.2022.03.015","volume":"184","author":"B Jia","year":"2022","unstructured":"Jia, B., Larbi, A., Lv, C., Liang, J., Xiang, D., Zhang, B., Fang, Y., Shen, W., Wu, G., Quan, G.: Identification and validation of ram sperm proteins associated with cryoinjuries caused by the cryopreservation process. Theriogenology. 184, 191\u2013203 (2022)","journal-title":"Theriogenology"},{"key":"12_CR85","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2022.836208","volume":"10","author":"M Zhang","year":"2022","unstructured":"Zhang, M., Chiozzi, R.Z., Skerrett-Byrne, D.A., Veenendaal, T., Klumperman, J., Heck, A.J.R., Nixon, B., Helms, J.B., Gadella, B.M., Bromfield, E.G.: High resolution proteomic analysis of subcellular fractionated boar spermatozoa provides comprehensive insights into perinuclear theca-residing proteins. Front. Cell Dev. Biol. 10, 836208 (2022)","journal-title":"Front. Cell Dev. Biol."},{"key":"12_CR86","doi-asserted-by":"publisher","DOI":"10.1016\/j.dib.2020.105887","volume":"31","author":"FE Mart\u00edn-Cano","year":"2020","unstructured":"Mart\u00edn-Cano, F.E., Gaitskell-Phillips, G., Ortiz-Rodr\u00edguez, J.M., Silva, A., Gil, C., Ortega-Ferrusola, C., Pe\u00f1a, F.J.: Data set of the proteome of fresh and frozen thawed stallion spermatozoa. Data Brief. 31, 105887 (2020)","journal-title":"Data Brief"},{"key":"12_CR87","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1111\/rda.13146","volume":"53","author":"R Singh","year":"2018","unstructured":"Singh, R., Sengar, G.S., Singh, U., Deb, R., Junghare, V., Hazra, S., Kumar, S., Tyagi, S., Das, A.K., Raja, T.V., Kumar, A.: Functional proteomic analysis of crossbred (Holstein Friesian \u00d7 Sahiwal) bull spermatozoa. Reprod. Domest. Anim. 53, 588\u2013608 (2018)","journal-title":"Reprod. Domest. Anim."},{"key":"12_CR88","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1002\/mrd.23174","volume":"86","author":"O D'Amours","year":"2019","unstructured":"D'Amours, O., Calvo, \u00c9., Bourassa, S., Vincent, P., Blondin, P., Sullivan, R.: Proteomic markers of low and high fertility bovine spermatozoa separated by Percoll gradient. Mol. Reprod. Dev. 86, 999\u20131012 (2019)","journal-title":"Mol. Reprod. Dev."},{"key":"12_CR89","doi-asserted-by":"publisher","first-page":"929","DOI":"10.1007\/s10930-021-10013-w","volume":"40","author":"J Liang","year":"2021","unstructured":"Liang, J., Zheng, Y., Zeng, W., Chen, L., Yang, S., Du, P., Wang, Y., Yu, X., Zhang, X.: Proteomic profile of sperm in infertile males reveals changes in metabolic pathways. Protein J. 40, 929\u2013939 (2021)","journal-title":"Protein J."},{"key":"12_CR90","doi-asserted-by":"publisher","first-page":"8601","DOI":"10.1021\/acsomega.1c06551","volume":"7","author":"S Ghosh","year":"2022","unstructured":"Ghosh, S., Parikh, S., Nissa, M.U., Acharjee, A., Singh, A., Patwa, D., Makwana, P., Athalye, A., Barpanda, A., Laloraya, M., Srivastava, S., Parikh, F.: Semen proteomics of COVID-19 convalescent men reveals disruption of key biological pathways relevant to male reproductive function. ACS Omega. 7, 8601\u20138612 (2022)","journal-title":"ACS Omega"},{"key":"12_CR91","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1017\/S1464793103006407","volume":"79","author":"S Meizel","year":"2004","unstructured":"Meizel, S.: The sperm, a neuron with a tail: 'neuronal' receptors in mammalian sperm. Biol. Rev. Camb. Philos. Soc. 79, 713\u2013732 (2004)","journal-title":"Biol. Rev. Camb. Philos. Soc."},{"key":"12_CR92","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0112834","volume":"9","author":"JA Urra","year":"2014","unstructured":"Urra, J.A., Villaroel-Esp\u00edndola, F., Covarrubias, A.A., Rodr\u00edguez-Gil, J.E., Ram\u00edrez-Reveco, A., Concha, I.I.: Presence and function of dopamine transporter (DAT) in stallion sperm: dopamine modulates sperm motility and acrosomal integrity. PLoS One. 9, e112834 (2014)","journal-title":"PLoS One"},{"key":"12_CR93","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1016\/j.anireprosci.2011.07.001","volume":"127","author":"MA Puente","year":"2011","unstructured":"Puente, M.A., Tartaglione, C.M., Ritta, M.N.: Bull sperm acrosome reaction induced by gamma-aminobutyric acid (GABA) is mediated by GABAergic receptors type A. Anim. Reprod. Sci. 127, 31\u201337 (2011)","journal-title":"Anim. Reprod. Sci."},{"key":"12_CR94","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.autneu.2015.04.008","volume":"191","author":"GI Gorodeski","year":"2015","unstructured":"Gorodeski, G.I.: Purinergic signalling in the reproductive system. Auton. Neurosci. 191, 82\u2013101 (2015)","journal-title":"Auton. Neurosci."},{"key":"12_CR95","doi-asserted-by":"publisher","first-page":"25928","DOI":"10.1074\/jbc.M502435200","volume":"280","author":"P Kumar","year":"2005","unstructured":"Kumar, P., Meizel, S.: Nicotinic acetylcholine receptor subunits and associated proteins in human sperm. J. Biol. Chem. 280, 25928\u201325935 (2005)","journal-title":"J. Biol. Chem."},{"key":"12_CR96","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1002\/mrd.20336","volume":"72","author":"S Meizel","year":"2005","unstructured":"Meizel, S., Son, J.H.: Studies of sperm from mutant mice suggesting that two neurotransmitter receptors are important to the zona pellucida-initiated acrosome reaction. Mol. Reprod. Dev. 72, 250\u2013258 (2005)","journal-title":"Mol. Reprod. Dev."},{"key":"12_CR97","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1016\/j.fertnstert.2015.11.004","volume":"105","author":"M Gianzo","year":"2016","unstructured":"Gianzo, M., Mu\u00f1oa-Hoyos, I., Urizar-Arenaza, I., Larreategui, Z., Quintana, F., Garrido, N., Subir\u00e1n, N., Irazusta, J.: Angiotensin II type 2 receptor is expressed in human sperm cells and is involved in sperm motility. Fertil. Steril. 105, 608\u2013616 (2016)","journal-title":"Fertil. Steril."},{"key":"12_CR98","doi-asserted-by":"publisher","first-page":"2058","DOI":"10.1093\/humrep\/det232","volume":"28","author":"AA Amoako","year":"2013","unstructured":"Amoako, A.A., Marczylo, T.H., Marczylo, E.L., Elson, J., Willets, J.M., Taylor, A.H., Konje, J.C.: Anandamide modulates human sperm motility: implications for men with asthenozoospermia and oligoasthenoteratozoospermia. Hum. Reprod. 28, 2058\u20132066 (2013)","journal-title":"Hum. Reprod."},{"key":"12_CR99","first-page":"73","volume":"2","author":"C Flegel","year":"2015","unstructured":"Flegel, C., Vogel, F., Hofreuter, A., Schreiner, B.S., Osthold, S., Veitinger, S., Becker, C., Brockmeyer, N.H., Muschol, M., Wennemuth, G., Altm\u00fcller, J., Hatt, H., et al.: Characterization of the olfactory receptors expressed in human spermatozoa. Front. Mol. Biosci. 2, 73 (2015)","journal-title":"Front. Mol. Biosci."},{"key":"12_CR100","doi-asserted-by":"publisher","first-page":"560","DOI":"10.1016\/j.rbmo.2018.01.007","volume":"36","author":"M Cort\u00e9s-Rodriguez","year":"2018","unstructured":"Cort\u00e9s-Rodriguez, M., Royo, J.L., Reyes-Palomares, A., Lend\u00ednez, A.M., Ruiz-Gald\u00f3n, M., Reyes-Engel, A.: Sperm count and motility are quantitatively affected by functional polymorphisms of HTR2A, MAOA and SLC18A. Reprod. Biomed. Online. 36, 560\u2013567 (2018)","journal-title":"Reprod. Biomed. Online"},{"key":"12_CR101","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1159\/000076290","volume":"103","author":"J Guo","year":"2003","unstructured":"Guo, J., Zhu, P., Wu, C., Yu, L., Zhao, S., Gu, X.: In silico analysis indicates a similar gene expression pattern between human brain and testis. Cytogenet. Genome Res. 103, 58\u201362 (2003)","journal-title":"Cytogenet. Genome Res."},{"key":"12_CR102","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1006\/nbdi.1996.0002","volume":"3","author":"AH Sharp","year":"1996","unstructured":"Sharp, A.H., Ross, C.A.: Neurobiology of Huntington's disease. Neurobiol. Dis. 3, 3\u201315 (1996)","journal-title":"Neurobiol. Dis."},{"key":"12_CR103","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.neuropharm.2018.03.009","volume":"135","author":"M Caterino","year":"2018","unstructured":"Caterino, M., Squillaro, T., Montesarchio, D., Giordano, A., Giancola, C., Melone, M.A.B.: Huntingtin protein: a new option for fixing the Huntington's disease countdown clock. Neuropharmacology. 135, 126\u2013138 (2018)","journal-title":"Neuropharmacology"},{"key":"12_CR104","volume":"3","author":"EM Gatto","year":"2020","unstructured":"Gatto, E.M., Rojas, N.G., Persi, G., Etcheverry, J.L., Cesarini, M.E., Perandones, C.: Huntington disease: advances in the understanding of its mechanisms. Clin. Park. Relat. Disord. 3, 100056 (2020)","journal-title":"Clin. Park. Relat. Disord."},{"key":"12_CR105","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1038\/s41582-020-0389-4","volume":"16","author":"SJ Tabrizi","year":"2020","unstructured":"Tabrizi, S.J., Flower, M.D., Ross, C.A., Wild, E.J.: Huntington disease: new insights into molecular pathogenesis and therapeutic opportunities. Nat. Rev. Neurol. 16, 529\u2013546 (2020)","journal-title":"Nat. Rev. Neurol."},{"key":"12_CR106","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1177\/1073858410390378","volume":"17","author":"DE Ehrnhoefer","year":"2011","unstructured":"Ehrnhoefer, D.E., Sutton, L., Hayden, M.R.: Small changes, big impact: posttranslational modifications and function of huntingtin in Huntington disease. Neuroscientist. 17, 475\u2013492 (2011)","journal-title":"Neuroscientist"},{"key":"12_CR107","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1007\/s10072-013-1515-5","volume":"35","author":"W Im","year":"2014","unstructured":"Im, W., Chung, J., Lee, S.T., Chu, K., Kim, M.W., Kim, M.: Nuclear localization of huntingtin during spermatogenesis. Neurol. Sci. 35, 459\u2013462 (2014)","journal-title":"Neurol. Sci."},{"key":"12_CR108","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1086\/318207","volume":"68","author":"BR Leavitt","year":"2001","unstructured":"Leavitt, B.R., Guttman, J.A., Hodgson, J.G., Kimel, G.H., Singaraja, R., Vogl, A.W., Hayden, M.R.: Wild-type huntingtin reduces the cellular toxicity of mutant huntingtin in vivo. Am. J. Hum. Genet. 68, 313\u2013324 (2001)","journal-title":"Am. J. Hum. Genet."},{"key":"12_CR109","doi-asserted-by":"publisher","first-page":"492","DOI":"10.1242\/jcs.173666","volume":"129","author":"J Yan","year":"2016","unstructured":"Yan, J., Zhang, H., Liu, Y., Zhao, F., Zhu, S., Xie, C., Tang, T.S., Guo, C.: Germline deletion of huntingtin causes male infertility and arrested spermiogenesis in mice. J. Cell Sci. 129, 492\u2013501 (2016)","journal-title":"J. Cell Sci."},{"key":"12_CR110","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1023\/A:1005388218625","volume":"20","author":"PS Harper","year":"1997","unstructured":"Harper, P.S.: Trinucleotide repeat disorders. J. Inherit. Metab. Dis. 20, 122\u2013124 (1997)","journal-title":"J. Inherit. Metab. Dis."},{"key":"12_CR111","doi-asserted-by":"publisher","first-page":"R47","DOI":"10.1186\/gb-2004-5-7-r47","volume":"5","author":"H Huang","year":"2004","unstructured":"Huang, H., Winter, E.E., Wang, H., Weinstock, K.G., Xing, H., Goodstadt, L., Stenson, P.D., Cooper, D.N., Smith, D., Alb\u00e0, M.M., Ponting, C.P., Fechtel, K.: Evolutionary conservation and selection of human disease gene orthologs in the rat and mouse genomes. Genome Biol. 5, R47 (2004)","journal-title":"Genome Biol."},{"key":"12_CR112","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1038\/nrg2748","volume":"11","author":"AR La Spada","year":"2010","unstructured":"La Spada, A.R., Taylor, J.P.: Repeat expansion disease: progress and puzzles in disease pathogenesis. Nat. Rev. Genet. 11, 247\u2013258 (2010)","journal-title":"Nat. Rev. Genet."},{"key":"12_CR113","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1038\/nrg1689","volume":"6","author":"CE Pearson","year":"2005","unstructured":"Pearson, C.E., Nichol Edamura, K., Cleary, J.D.: Repeat instability: mechanisms of dynamic mutations. Nat. Rev. Genet. 6, 729\u2013742 (2005)","journal-title":"Nat. Rev. Genet."},{"key":"12_CR114","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1101\/gr.1925704","volume":"14","author":"MM Alb\u00e0","year":"2004","unstructured":"Alb\u00e0, M.M., Guig\u00f3, R.: Comparative analysis of amino acid repeats in rodents and humans. Genome Res. 14, 549\u2013554 (2004)","journal-title":"Genome Res."},{"key":"12_CR115","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1186\/1471-2164-11-654","volume":"11","author":"V Whan","year":"2010","unstructured":"Whan, V., Hobbs, M., McWilliam, S., Lynn, D.J., Lutzow, Y.S., Khatkar, M., Barendse, W., Raadsma, H., Tellam, R.L.: Bovine proteins containing poly-glutamine repeats are often polymorphic and enriched for components of transcriptional regulatory complexes. BMC Genomics. 11, 654 (2010)","journal-title":"BMC Genomics"},{"key":"12_CR116","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1007\/s10048-007-0088-y","volume":"8","author":"LB Madsen","year":"2007","unstructured":"Madsen, L.B., Thomsen, B., S\u00f8lvsten, C.A., Bendixen, C., Fredholm, M., J\u00f8rgensen, A.L., Nielsen, A.L.: Identification of the porcine homologous of human disease causing trinucleotide repeat sequences. Neurogenetics. 8, 207\u2013218 (2007)","journal-title":"Neurogenetics"},{"key":"12_CR117","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1111\/j.1745-7262.2007.00309.x","volume":"9","author":"GA Cornwall","year":"2007","unstructured":"Cornwall, G.A., von Horsten, H.H., Swartz, D., Johnson, S., Chau, K., Whelly, S.: Extracellular quality control in the epididymis. Asian J. Androl. 9, 500\u2013507 (2007)","journal-title":"Asian J. Androl."},{"key":"12_CR118","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0036394","volume":"7","author":"S Whelly","year":"2012","unstructured":"Whelly, S., Johnson, S., Powell, J., Borchardt, C., Hastert, M.C., Cornwall, G.A.: Nonpathological extracellular amyloid is present during normal epididymal sperm maturation. PLoS One. 7, e36394 (2012)","journal-title":"PLoS One"},{"key":"12_CR119","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.660626","volume":"9","author":"SL Cafe","year":"2021","unstructured":"Cafe, S.L., Nixon, B., Ecroyd, H., Martin, J.H., Skerrett-Byrne, D.A., Bromfield, E.G.: Proteostasis in the male and female germline: a new outlook on the maintenance of reproductive health. Front. Cell Dev. Biol. 9, 660626 (2021)","journal-title":"Front. Cell Dev. Biol."},{"key":"12_CR120","doi-asserted-by":"crossref","unstructured":"Bisconti, M., Simon, J.F., Grassi, S., Leroy, B., Martinet, B., Arcolia, V., Isachenko, V., Hennebert, E.: Influence of risk factors for male infertility on sperm protein composition. Int. J. Mol. Sci. 22 (2021)","DOI":"10.3390\/ijms222313164"},{"key":"12_CR121","doi-asserted-by":"publisher","DOI":"10.1002\/prca.201900007","volume":"13","author":"Y Guo","year":"2019","unstructured":"Guo, Y., Jiang, J., Zhang, H., Wen, Y., Zhang, H., Cui, Y., Tian, J., Jiang, M., Liu, X., Wang, G., Li, Y., Hu, Z., et al.: Proteomic analysis of Dpy19l2-deficient human globozoospermia reveals multiple molecular defects. Proteomics Clin. Appl. 13, e1900007 (2019)","journal-title":"Proteomics Clin. Appl."},{"key":"12_CR122","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1093\/molehr\/gaq009","volume":"16","author":"AB Siva","year":"2010","unstructured":"Siva, A.B., Kameshwari, D.B., Singh, V., Pavani, K., Sundaram, C.S., Rangaraj, N., Deenadayal, M., Shivaji, S.: Proteomics-based study on asthenozoospermia: differential expression of proteasome alpha complex. Mol. Hum. Reprod. 16, 452\u2013462 (2010)","journal-title":"Mol. Hum. Reprod."},{"key":"12_CR123","doi-asserted-by":"publisher","first-page":"176","DOI":"10.3109\/01913123.2013.763881","volume":"37","author":"F De Amicis","year":"2013","unstructured":"De Amicis, F., Perrotta, I., Santoro, M., Guido, C., Morelli, C., Cesario, M.G., Bruno, R., Aquila, S.: Human sperm anatomy: different expression and localization of phosphatidylinositol 3-kinase in normal and varicocele human spermatozoa. Ultrastruct. Pathol. 37, 176\u2013182 (2013)","journal-title":"Ultrastruct. Pathol."},{"key":"12_CR124","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/j.urology.2012.06.027","volume":"81","author":"H Hosseinifar","year":"2013","unstructured":"Hosseinifar, H., Gourabi, H., Salekdeh, G.H., Alikhani, M., Mirshahvaladi, S., Sabbaghian, M., Modarresi, T., Gilani, M.A.: Study of sperm protein profile in men with and without varicocele using two-dimensional gel electrophoresis. Urology. 81, 293\u2013300 (2013)","journal-title":"Urology"},{"key":"12_CR125","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/s12958-015-0007-2","volume":"13","author":"A Agarwal","year":"2015","unstructured":"Agarwal, A., Sharma, R., Durairajanayagam, D., Ayaz, A., Cui, Z., Willard, B., Gopalan, B., Sabanegh, E.: Major protein alterations in spermatozoa from infertile men with unilateral varicocele. Reprod. Biol. Endocrinol. 13, 8 (2015)","journal-title":"Reprod. Biol. Endocrinol."},{"key":"12_CR126","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1016\/j.urology.2014.11.030","volume":"85","author":"A Agarwal","year":"2015","unstructured":"Agarwal, A., Sharma, R., Durairajanayagam, D., Cui, Z., Ayaz, A., Gupta, S., Willard, B., Gopalan, B., Sabanegh, E.: Differential proteomic profiling of spermatozoal proteins of infertile men with unilateral or bilateral varicocele. Urology. 85, 580\u2013588 (2015)","journal-title":"Urology"},{"key":"12_CR127","doi-asserted-by":"publisher","first-page":"43","DOI":"10.4103\/1008-682X.153848","volume":"18","author":"A Agarwal","year":"2016","unstructured":"Agarwal, A., Sharma, R., Durairajanayagam, D., Cui, Z., Ayaz, A., Gupta, S., Willard, B., Gopalan, B., Sabanegh, E.: Spermatozoa protein alterations in infertile men with bilateral varicocele. Asian J. Androl. 18, 43\u201353 (2016)","journal-title":"Asian J. Androl."},{"key":"12_CR128","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1016\/j.juro.2018.03.009","volume":"200","author":"L Samanta","year":"2018","unstructured":"Samanta, L., Agarwal, A., Swain, N., Sharma, R., Gopalan, B., Esteves, S.C., Durairajanayagam, D., Sabanegh, E.: Proteomic signatures of sperm mitochondria in varicocele: clinical use as biomarkers of varicocele associated infertility. J. Urol. 200, 414\u2013422 (2018)","journal-title":"J. Urol."},{"key":"12_CR129","doi-asserted-by":"publisher","first-page":"521","DOI":"10.5534\/wjmh.190012","volume":"38","author":"AD Martins","year":"2020","unstructured":"Martins, A.D., Agarwal, A., Baskaran, S., Pushparaj, P.N., Ahmad, G., Panner Selvam, M.K.: Alterations of spermatozoa proteomic profile in men with Hodgkin's disease prior to cancer therapy. World J. Mens Health. 38, 521\u2013534 (2020)","journal-title":"World J. Mens Health"},{"key":"12_CR130","doi-asserted-by":"publisher","first-page":"198","DOI":"10.5534\/wjmh.180099","volume":"38","author":"TR Dias","year":"2020","unstructured":"Dias, T.R., Agarwal, A., Pushparaj, P.N., Ahmad, G., Sharma, R.: New insights on the mechanisms affecting fertility in men with non-seminoma testicular cancer before cancer therapy. World J. Mens Health. 38, 198\u2013207 (2020)","journal-title":"World J. Mens Health"},{"key":"12_CR131","doi-asserted-by":"crossref","unstructured":"Panner Selvam, M.K., Finelli, R., Baskaran, S., Agarwal, A.: Dysregulation of key proteins associated with sperm motility and fertility potential in cancer patients. Int. J. Mol. Sci. 21 (2020)","DOI":"10.3390\/ijms21186754"},{"key":"12_CR132","doi-asserted-by":"publisher","first-page":"1058250","DOI":"10.3389\/fendo.2022.1058250","volume":"13","author":"Y Guo","year":"2022","unstructured":"Guo, Y., Li, J., Hao, F., Yang, Y., Yang, H., Chang, Q., Kong, P., Liu, W., Jiao, X., Teng, X.: A new perspective on semen quality of aged male: the characteristics of metabolomics and proteomics. Front. Endocrinol. (Lausanne). 13, 1058250 (2022)","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"12_CR133","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1007\/s10815-020-01707-8","volume":"37","author":"T Pini","year":"2020","unstructured":"Pini, T., Parks, J., Russ, J., Dzieciatkowska, M., Hansen, K.C., Schoolcraft, W.B., Katz-Jaffe, M.: Obesity significantly alters the human sperm proteome, with potential implications for fertility. J. Assist. Reprod. Genet. 37, 777\u2013787 (2020)","journal-title":"J. Assist. Reprod. Genet."},{"key":"12_CR134","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1111\/andr.289","volume":"3","author":"Y Liu","year":"2015","unstructured":"Liu, Y., Guo, Y., Song, N., Fan, Y., Li, K., Teng, X., Guo, Q., Ding, Z.: Proteomic pattern changes associated with obesity-induced asthenozoospermia. Andrology. 3, 247\u2013259 (2015)","journal-title":"Andrology"},{"key":"12_CR135","doi-asserted-by":"publisher","first-page":"43475","DOI":"10.1038\/srep43475","volume":"7","author":"Y Mu","year":"2017","unstructured":"Mu, Y., Yan, W.J., Yin, T.L., Zhang, Y., Li, J., Yang, J.: Diet-induced obesity impairs spermatogenesis: a potential role for autophagy. Sci. Rep. 7, 43475 (2017)","journal-title":"Sci. Rep."},{"key":"12_CR136","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.theriogenology.2020.09.023","volume":"158","author":"F Wang","year":"2020","unstructured":"Wang, F., Chen, H., Chen, Y., Cheng, Y., Li, J., Zheng, L., Zeng, X., Luo, T.: Diet-induced obesity is associated with altered expression of sperm motility-related genes and testicular post-translational modifications in a mouse model. Theriogenology. 158, 233\u2013238 (2020)","journal-title":"Theriogenology"},{"key":"12_CR137","doi-asserted-by":"publisher","first-page":"M110.007187","DOI":"10.1074\/mcp.M110.007187","volume":"10","author":"U Paasch","year":"2011","unstructured":"Paasch, U., Heidenreich, F., Pursche, T., Kuhlisch, E., Kettner, K., Grunewald, S., Kratzsch, J., Dittmar, G., Glander, H.J., Hoflack, B., Kriegel, T.M.: Identification of increased amounts of eppin protein complex components in sperm cells of diabetic and obese individuals by difference gel electrophoresis. Mol. Cell. Proteomics. 10, M110.007187 (2011)","journal-title":"Mol. Cell. Proteomics"},{"key":"12_CR138","doi-asserted-by":"publisher","first-page":"2267","DOI":"10.1093\/humrep\/des173","volume":"27","author":"B Muciaccia","year":"2012","unstructured":"Muciaccia, B., Pensini, S., Culasso, F., Padula, F., Paoli, D., Gandini, L., Di Veroli, C., Bianchini, G., Stefanini, M., D'Agostino, A.: Higher clusterin immunolabeling and sperm DNA damage levels in hypertensive men compared with controls. Hum. Reprod. 27, 2267\u20132276 (2012)","journal-title":"Hum. Reprod."},{"key":"12_CR139","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1002\/mrd.22930","volume":"85","author":"T An","year":"2018","unstructured":"An, T., Wang, Y.F., Liu, J.X., Pan, Y.Y., Liu, Y.F., He, Z.C., Mo, F.F., Li, J., Kang, L.H., Gu, Y.J., Lv, B.H., Gao, S.H., et al.: Comparative analysis of proteomes between diabetic and normal human sperm: insights into the effects of diabetes on male reproduction based on the regulation of mitochondria-related proteins. Mol. Reprod. Dev. 85, 7\u201316 (2018)","journal-title":"Mol. Reprod. Dev."},{"key":"12_CR140","doi-asserted-by":"publisher","first-page":"2628","DOI":"10.1021\/acs.jproteome.0c01044","volume":"20","author":"MG Carvalho","year":"2021","unstructured":"Carvalho, M.G., Silva, K.M., Aristizabal, V.H.V., Ortiz, P.E.O., Paranzini, C.S., Melchert, A., Amaro, J.L., Souza, F.F.: Effects of obesity and diabetes on sperm cell proteomics in rats. J. Proteome Res. 20, 2628\u20132642 (2021)","journal-title":"J. Proteome Res."},{"key":"12_CR141","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1093\/abbs\/gmv045","volume":"47","author":"X Chen","year":"2015","unstructured":"Chen, X., Xu, W., Miao, M., Zhu, Z., Dai, J., Chen, Z., Fang, P., Wu, J., Nie, D., Wang, L., Wang, Z., Qiao, Z., et al.: Alteration of sperm protein profile induced by cigarette smoking. Acta Biochim. Biophys. Sin. Shanghai. 47, 504\u2013515 (2015)","journal-title":"Acta Biochim. Biophys. Sin. Shanghai"},{"key":"12_CR142","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1530\/REP-09-0492","volume":"139","author":"V Shrivastava","year":"2010","unstructured":"Shrivastava, V., Pekar, M., Grosser, E., Im, J., Vigodner, M.: SUMO proteins are involved in the stress response during spermatogenesis and are localized to DNA double-strand breaks in germ cells. Reproduction. 139, 999\u20131010 (2010)","journal-title":"Reproduction"},{"key":"12_CR143","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.reprotox.2013.12.001","volume":"43","author":"V Shrivastava","year":"2014","unstructured":"Shrivastava, V., Marmor, H., Chernyak, S., Goldstein, M., Feliciano, M., Vigodner, M.: Cigarette smoke affects posttranslational modifications and inhibits capacitation-induced changes in human sperm proteins. Reprod. Toxicol. 43, 125\u2013129 (2014)","journal-title":"Reprod. Toxicol."},{"key":"12_CR144","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1095\/biolreprod.115.131656","volume":"94","author":"D Nie","year":"2016","unstructured":"Nie, D., Zhang, D., Dai, J., Zhang, M., Zhao, X., Xu, W., Chen, Z., Wang, L., Wang, Z., Qiao, Z.: Nicotine induced murine spermatozoa apoptosis via up-regulation of deubiquitinated RIP1 by Trim27 promoter hypomethylation. Biol. Reprod. 94, 31 (2016)","journal-title":"Biol. Reprod."},{"key":"12_CR145","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1016\/j.biocel.2012.12.007","volume":"45","author":"Z Zhu","year":"2013","unstructured":"Zhu, Z., Xu, W., Dai, J., Chen, X., Zhao, X., Fang, P., Yang, F., Tang, M., Wang, Z., Wang, L., Ma, D., Qaio, Z.: The alteration of protein profile induced by cigarette smoking via oxidative stress in mice epididymis. Int. J. Biochem. Cell Biol. 45, 571\u2013582 (2013)","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"12_CR146","doi-asserted-by":"publisher","first-page":"2597","DOI":"10.1093\/humrep\/dev214","volume":"30","author":"EG Bromfield","year":"2015","unstructured":"Bromfield, E.G., Aitken, R.J., Anderson, A.L., McLaughlin, E.A., Nixon, B.: The impact of oxidative stress on chaperone-mediated human sperm-egg interaction. Hum. Reprod. 30, 2597\u20132613 (2015)","journal-title":"Hum. Reprod."},{"key":"12_CR147","first-page":"91","volume":"23","author":"EG Bromfield","year":"2017","unstructured":"Bromfield, E.G., Aitken, R.J., McLaughlin, E.A., Nixon, B.: Proteolytic degradation of heat shock protein A2 occurs in response to oxidative stress in male germ cells of the mouse. Mol. Hum. Reprod. 23, 91\u2013105 (2017)","journal-title":"Mol. Hum. Reprod."},{"key":"12_CR148","first-page":"101","volume":"72","author":"T Mari\u0107","year":"2021","unstructured":"Mari\u0107, T., Fu\u010di\u0107, A., Aghayanian, A.: Environmental and occupational exposures associated with male infertility. Arh. Hig. Rada Toksikol. 72, 101\u2013113 (2021)","journal-title":"Arh. Hig. Rada Toksikol."},{"key":"12_CR149","doi-asserted-by":"publisher","first-page":"9169","DOI":"10.1038\/srep09169","volume":"5","author":"MS Rahman","year":"2015","unstructured":"Rahman, M.S., Kwon, W.S., Lee, J.S., Yoon, S.J., Ryu, B.Y., Pang, M.G.: Bisphenol-A affects male fertility via fertility-related proteins in spermatozoa. Sci. Rep. 5, 9169 (2015)","journal-title":"Sci. Rep."},{"key":"12_CR150","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1186\/s12864-016-2979-5","volume":"17","author":"MS Rahman","year":"2016","unstructured":"Rahman, M.S., Kwon, W.S., Yoon, S.J., Park, Y.J., Ryu, B.Y., Pang, M.G.: A novel approach to assessing bisphenol-A hazards using an in vitro model system. BMC Genomics. 17, 577 (2016)","journal-title":"BMC Genomics"},{"key":"12_CR151","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1289\/EHP378","volume":"125","author":"MS Rahman","year":"2017","unstructured":"Rahman, M.S., Kwon, W.S., Karmakar, P.C., Yoon, S.J., Ryu, B.Y., Pang, M.G.: Gestational exposure to bisphenol A affects the function and proteome profile of F1 spermatozoa in adult mice. Environ. Health Perspect. 125, 238\u2013245 (2017)","journal-title":"Environ. Health Perspect."},{"key":"12_CR152","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1021\/acs.jproteome.7b00668","volume":"17","author":"MS Rahman","year":"2018","unstructured":"Rahman, M.S., Kwon, W.S., Ryu, D.Y., Khatun, A., Karmakar, P.C., Ryu, B.Y., Pang, M.G.: Functional and proteomic alterations of F1 capacitated spermatozoa of adult mice following gestational exposure to bisphenol A. J. Proteome Res. 17, 524\u2013535 (2018)","journal-title":"J. Proteome Res."},{"key":"12_CR153","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0124296","volume":"10","author":"MA Brie\u00f1o-Enr\u00edquez","year":"2015","unstructured":"Brie\u00f1o-Enr\u00edquez, M.A., Garc\u00eda-L\u00f3pez, J., C\u00e1rdenas, D.B., Guibert, S., Cleroux, E., D\u011bd, L., Hourcade Jde, D., P\u011bknicov\u00e1, J., Weber, M., Del Mazo, J.: Exposure to endocrine disruptor induces transgenerational epigenetic deregulation of microRNAs in primordial germ cells. PLoS One. 10, e0124296 (2015)","journal-title":"PLoS One"},{"key":"12_CR154","doi-asserted-by":"publisher","first-page":"1181","DOI":"10.1002\/tox.23117","volume":"36","author":"S Huang","year":"2021","unstructured":"Huang, S., Lu, Y., Li, S., Zhou, T., Wang, J., Xia, J., Zhang, X., Zhou, Z.: Key proteins of proteome underlying sperm malformation of rats exposed to low fenvalerate doses are highly related to P53. Environ. Toxicol. 36, 1181\u20131194 (2021)","journal-title":"Environ. Toxicol."},{"key":"12_CR155","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1530\/REP-20-0286","volume":"160","author":"A Komsky-Elbaz","year":"2020","unstructured":"Komsky-Elbaz, A., Kalo, D., Roth, Z.: Effect of aflatoxin B1 on bovine spermatozoa's proteome and embryo's transcriptome. Reproduction. 160, 709\u2013723 (2020)","journal-title":"Reproduction"},{"key":"12_CR156","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1016\/j.chemosphere.2018.05.153","volume":"207","author":"Z Sun","year":"2018","unstructured":"Sun, Z., Wei, R., Luo, G., Niu, R., Wang, J.: Proteomic identification of sperm from mice exposed to sodium fluoride. Chemosphere. 207, 676\u2013681 (2018)","journal-title":"Chemosphere"},{"key":"12_CR157","doi-asserted-by":"publisher","first-page":"1117155","DOI":"10.3389\/fcell.2023.1117155","volume":"11","author":"J Nayak","year":"2023","unstructured":"Nayak, J., Jena, S.R., Kumar, S., Kar, S., Dixit, A., Samanta, L.: Human sperm proteome reveals the effect of environmental borne seminal polyaromatic hydrocarbons exposome in etiology of idiopathic male factor infertility. Front. Cell Dev. Biol. 11, 1117155 (2023)","journal-title":"Front. Cell Dev. Biol."},{"key":"12_CR158","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/j.fct.2018.01.044","volume":"113","author":"C Nerin","year":"2018","unstructured":"Nerin, C., Canellas, E., Vera, P., Garcia-Calvo, E., Luque-Garcia, J.L., C\u00e1mara, C., Ausejo, R., Miguel, J., Mendoza, N.: A common surfactant used in food packaging found to be toxic for reproduction in mammals. Food Chem. Toxicol. 113, 115\u2013124 (2018)","journal-title":"Food Chem. Toxicol."},{"key":"12_CR159","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1126\/science.add2209","volume":"380","author":"NS Upham","year":"2023","unstructured":"Upham, N.S., Landis, M.J.: Genomics expands the mammalverse. Science. 380, 358\u2013359 (2023)","journal-title":"Science"},{"key":"12_CR160","doi-asserted-by":"publisher","first-page":"74ra24","DOI":"10.1126\/scitranslmed.3001868","volume":"3","author":"LS Ostedgaard","year":"2011","unstructured":"Ostedgaard, L.S., Meyerholz, D.K., Chen, J.H., Pezzulo, A.A., Karp, P.H., Rokhlina, T., Ernst, S.E., Hanfland, R.A., Reznikov, L.R., Ludwig, P.S., Rogan, M.P., Davis, G.J., et al.: The DeltaF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs. Sci. Transl. Med. 3, 74ra24 (2011)","journal-title":"Sci. Transl. Med."},{"key":"12_CR161","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1016\/j.theriogenology.2014.10.001","volume":"83","author":"SL Pratt","year":"2015","unstructured":"Pratt, S.L., Stowe, H.M., Whitlock, B.K., Strickland, L., Miller, M., Calcatera, S.M., Dimmick, M.D., Aiken, G.E., Schrick, F.N., Long, N.M., Duckett, S.K., Andrae, J.G.: Bulls grazing Kentucky 31 tall fescue exhibit impaired growth, semen quality, and decreased semen freezing potential. Theriogenology. 83, 408\u2013414 (2015)","journal-title":"Theriogenology"},{"key":"12_CR162","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/j.theriogenology.2021.07.006","volume":"172","author":"TW Geary","year":"2021","unstructured":"Geary, T.W., Waterman, R.C., Van Emon, M.L., Ratzburg, C.R., Lake, S., Eik, B.A., Armstrong, D.R., Zezeski, A.L., Heldt, J.S.: Effect of supplemental trace minerals on standard and novel measures of bull fertility. Theriogenology. 172, 307\u2013314 (2021)","journal-title":"Theriogenology"},{"key":"12_CR163","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0378-4320(03)00082-4","volume":"79","author":"LF Brito","year":"2003","unstructured":"Brito, L.F., Silva, A.E., Barbosa, R.T., Unanian, M.M., Kastelic, J.P.: Effects of scrotal insulation on sperm production, semen quality, and testicular echotexture in Bos indicus and Bos indicus x Bos taurus bulls. Anim. Reprod. Sci. 79, 1\u201315 (2003)","journal-title":"Anim. Reprod. Sci."},{"key":"12_CR164","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1016\/j.theriogenology.2005.12.012","volume":"66","author":"AL Ruiz-S\u00e1nchez","year":"2006","unstructured":"Ruiz-S\u00e1nchez, A.L., O'Donoghue, R., Novak, S., Dyck, M.K., Cosgrove, J.R., Dixon, W.T., Foxcroft, G.R.: The predictive value of routine semen evaluation and IVF technology for determining relative boar fertility. Theriogenology. 66, 736\u2013748 (2006)","journal-title":"Theriogenology"},{"key":"12_CR165","doi-asserted-by":"publisher","first-page":"779","DOI":"10.2527\/jas.2011-4311","volume":"90","author":"ML Broekhuijse","year":"2012","unstructured":"Broekhuijse, M.L., \u0160o\u0161tari\u0107, E., Feitsma, H., Gadella, B.M.: Application of computer-assisted semen analysis to explain variations in pig fertility. J. Anim. Sci. 90, 779\u2013789 (2012)","journal-title":"J. Anim. Sci."},{"key":"12_CR166","doi-asserted-by":"publisher","first-page":"135","DOI":"10.2298\/BAH1702135S","volume":"33","author":"R Savi\u0107","year":"2017","unstructured":"Savi\u0107, R., Marcos, R.A., Petrovi\u0107, M., Radojkovi\u0107, D., Radovi\u0107, \u010c., Gogi\u0107, M.: Fertility of boars \u2013 what is important to know. Biotechnol. Anim. Husb. 33, 135\u2013149 (2017)","journal-title":"Biotechnol. Anim. Husb."},{"key":"12_CR167","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1186\/s12864-019-5644-y","volume":"20","author":"JP Nani","year":"2019","unstructured":"Nani, J.P., Rezende, F.M., Pe\u00f1agaricano, F.: Predicting male fertility in dairy cattle using markers with large effect and functional annotation data. BMC Genomics. 20, 258 (2019)","journal-title":"BMC Genomics"},{"key":"12_CR168","doi-asserted-by":"crossref","unstructured":"Dordas-Perpiny\u00e0, M., Sergeant, N., Ruelle, I., Bruyas, J.F., Charreaux, F., Michaud, S., Carracedo, S., Catal\u00e1n, J., Mir\u00f3, J., Delehedde, M., Briand-Amirat, L.: ProAKAP4 semen concentrations as a valuable marker protein of post-thawed semen quality and bull fertility: a retrospective study. Vet. Sci. 9 (2022)","DOI":"10.3390\/vetsci9050224"},{"key":"12_CR169","doi-asserted-by":"publisher","first-page":"2481","DOI":"10.3168\/jds.2007-0743","volume":"91","author":"MT Kuhn","year":"2008","unstructured":"Kuhn, M.T., Hutchison, J.L.: Prediction of dairy bull fertility from field data: use of multiple services and identification and utilization of factors affecting bull fertility. J. Dairy Sci. 91, 2481\u20132492 (2008)","journal-title":"J. Dairy Sci."},{"key":"12_CR170","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1186\/s12863-016-0454-6","volume":"17","author":"Y Han","year":"2016","unstructured":"Han, Y., Pe\u00f1agaricano, F.: Unravelling the genomic architecture of bull fertility in Holstein cattle. BMC Genet. 17, 143 (2016)","journal-title":"BMC Genet."},{"key":"12_CR171","doi-asserted-by":"publisher","first-page":"116","DOI":"10.4308\/hjb.27.2.116","volume":"27","author":"NA Kutchy","year":"2020","unstructured":"Kutchy, N.A., Dogan, S., Wang, X., Topper, E., Kaya, A., Memili, E.: Application of proteomics to identify fertility markers in angus bull sperm. HAYATI J. Biosci. 27, 116\u2013135 (2020)","journal-title":"HAYATI J. Biosci."},{"key":"12_CR172","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2021.104135","volume":"236","author":"J Willforss","year":"2021","unstructured":"Willforss, J., Morrell, J.M., Resj\u00f6, S., Hallap, T., Padrik, P., Siino, V., de Koning, D.J., Andreasson, E., Levander, F., Humblot, P.: Stable bull fertility protein markers in seminal plasma. J. Proteome. 236, 104135 (2021)","journal-title":"J. Proteome"},{"key":"12_CR173","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.theriogenology.2018.06.021","volume":"119","author":"MK Muhammad Aslam","year":"2018","unstructured":"Muhammad Aslam, M.K., Sharma, V.K., Pandey, S., Kumaresan, A., Srinivasan, A., Datta, T.K., Mohanty, T.K., Yadav, S.: Identification of biomarker candidates for fertility in spermatozoa of crossbred bulls through comparative proteomics. Theriogenology. 119, 43\u201351 (2018)","journal-title":"Theriogenology"},{"key":"12_CR174","doi-asserted-by":"publisher","first-page":"13821","DOI":"10.1038\/srep13821","volume":"5","author":"WS Kwon","year":"2015","unstructured":"Kwon, W.S., Oh, S.A., Kim, Y.J., Rahman, M.S., Park, Y.J., Pang, M.G.: Proteomic approaches for profiling negative fertility markers in inferior boar spermatozoa. Sci. Rep. 5, 13821 (2015)","journal-title":"Sci. Rep."},{"key":"12_CR175","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1007\/s00441-020-03181-1","volume":"380","author":"M Zigo","year":"2020","unstructured":"Zigo, M., Manaskova-Postlerova, P., Zuidema, D., Kerns, K., Jonakova, V., Tumova, L., Bubenickova, F., Sutovsky, P.: Porcine model for the study of sperm capacitation, fertilization and male fertility. Cell Tissue Res. 380, 237\u2013262 (2020)","journal-title":"Cell Tissue Res."},{"key":"12_CR176","doi-asserted-by":"publisher","first-page":"5","DOI":"10.3109\/19396368.2012.725120","volume":"59","author":"A L\u00f3pez Rodr\u00edguez","year":"2013","unstructured":"L\u00f3pez Rodr\u00edguez, A., Rijsselaere, T., Beek, J., Vyt, P., Van Soom, A., Maes, D.: Boar seminal plasma components and their relation with semen quality. Syst Biol Reprod Med. 59, 5\u201312 (2013)","journal-title":"Syst Biol Reprod Med"},{"key":"12_CR177","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.anireprosci.2014.06.008","volume":"148","author":"M Schulze","year":"2014","unstructured":"Schulze, M., Buder, S., R\u00fcdiger, K., Beyerbach, M., Waberski, D.: Influences on semen traits used for selection of young AI boars. Anim. Reprod. Sci. 148, 164\u2013170 (2014)","journal-title":"Anim. Reprod. Sci."},{"key":"12_CR178","doi-asserted-by":"publisher","DOI":"10.1016\/j.animal.2023.100720","volume":"17","author":"C Maside","year":"2023","unstructured":"Maside, C., Recuero, S., Salas-Huetos, A., Ribas-Maynou, J., Yeste, M.: Animal board invited review: An update on the methods for semen quality evaluation in swine \u2013 From farm to the lab. Animal. 17, 100720 (2023)","journal-title":"Animal"},{"key":"12_CR179","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1007\/s00441-019-03100-z","volume":"380","author":"D Zuidema","year":"2020","unstructured":"Zuidema, D., Sutovsky, P.: The domestic pig as a model for the study of mitochondrial inheritance. Cell Tissue Res. 380, 263\u2013271 (2020)","journal-title":"Cell Tissue Res."},{"key":"12_CR180","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/1471-2164-6-70","volume":"6","author":"R Wernersson","year":"2005","unstructured":"Wernersson, R., Schierup, M.H., J\u00f8rgensen, F.G., Gorodkin, J., Panitz, F., Staerfeldt, H.H., Christensen, O.F., Mailund, T., Hornsh\u00f8j, H., Klein, A., Wang, J., Liu, B., et al.: Pigs in sequence space: a 0.66X coverage pig genome survey based on shotgun sequencing. BMC Genomics. 6, 70 (2005)","journal-title":"BMC Genomics"},{"key":"12_CR181","volume-title":"The Minipig in Biomedical Research","author":"HD Dawson","year":"2011","unstructured":"Dawson, H.D.: A comparative assessment of the pig, mouse and human genomes: structural and functional analysis of genes involved in immunity and infammation. In: McAnulty, P.A., Dayan, A.D., Ganderup, N.C., Hastings, K.L. (eds.) The Minipig in Biomedical Research, 1st edn. CRC Press (2011)","edition":"1"},{"key":"12_CR182","doi-asserted-by":"publisher","first-page":"eabd5758","DOI":"10.1126\/scitranslmed.abd5758","volume":"13","author":"JK Lunney","year":"2021","unstructured":"Lunney, J.K., Van Goor, A., Walker, K.E., Hailstock, T., Franklin, J., Dai, C.: Importance of the pig as a human biomedical model. Sci. Transl. Med. 13, eabd5758 (2021)","journal-title":"Sci. Transl. Med."},{"key":"12_CR183","doi-asserted-by":"crossref","unstructured":"Perleberg, C., Kind, A., Schnieke, A.: Genetically engineered pigs as models for human disease. Dis. Model. Mech. 11 (2018)","DOI":"10.1242\/dmm.030783"},{"key":"12_CR184","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1007\/s11248-016-9933-9","volume":"25","author":"LR Bertolini","year":"2016","unstructured":"Bertolini, L.R., Meade, H., Lazzarotto, C.R., Martins, L.T., Tavares, K.C., Bertolini, M., Murray, J.D.: The transgenic animal platform for biopharmaceutical production. Transgenic Res. 25, 329\u2013343 (2016)","journal-title":"Transgenic Res."},{"key":"12_CR185","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1111\/xen.12258","volume":"23","author":"B Petersen","year":"2016","unstructured":"Petersen, B., Frenzel, A., Lucas-Hahn, A., Herrmann, D., Hassel, P., Klein, S., Ziegler, M., Hadeler, K.G., Niemann, H.: Efficient production of biallelic GGTA1 knockout pigs by cytoplasmic microinjection of CRISPR\/Cas9 into zygotes. Xenotransplantation. 23, 338\u2013346 (2016)","journal-title":"Xenotransplantation"},{"key":"12_CR186","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1093\/af\/vfz014","volume":"9","author":"E Wolf","year":"2019","unstructured":"Wolf, E., Kemter, E., Klymiuk, N., Reichart, B.: Genetically modified pigs as donors of cells, tissues, and organs for xenotransplantation. Anim. Front. 9, 13\u201320 (2019)","journal-title":"Anim. Front."},{"key":"12_CR187","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1038\/s41421-019-0084-z","volume":"5","author":"B Dorado","year":"2019","unstructured":"Dorado, B., Pl\u00f8en, G.G., Barettino, A., Mac\u00edas, A., Gonzalo, P., Andr\u00e9s-Manzano, M.J., Gonz\u00e1lez-G\u00f3mez, C., Gal\u00e1n-Arriola, C., Alfonso, J.M., Lobo, M., L\u00f3pez-Mart\u00edn, G.J., Molina, A., et al.: Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome. Cell Discov. 5, 16 (2019)","journal-title":"Cell Discov."},{"key":"12_CR188","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.theriogenology.2022.04.012","volume":"186","author":"S Navarro-Serna","year":"2022","unstructured":"Navarro-Serna, S., Dehesa-Etxebeste, M., Pi\u00f1eiro-Silva, C., Romar, R., Lopes, J.S., L\u00f3pez de Muna\u00edn, A., Gadea, J.: Generation of Calpain-3 knock-out porcine embryos by CRISPR-Cas9 electroporation and intracytoplasmic microinjection of oocytes before insemination. Theriogenology. 186, 175\u2013184 (2022)","journal-title":"Theriogenology"},{"key":"12_CR189","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1089\/crispr.2020.0078","volume":"4","author":"S Navarro-Serna","year":"2021","unstructured":"Navarro-Serna, S., Hachem, A., Canha-Gouveia, A., Hanbashi, A., Garrappa, G., Lopes, J.S., Par\u00eds-Oller, E., Sarr\u00edas-Gil, L., Flores-Flores, C., Bassett, A., S\u00e1nchez, R., Bermejo-\u00c1lvarez, P., et al.: Generation of nonmosaic, two-pore channel 2 Biallelic knockout pigs in one generation by CRISPR-Cas9 microinjection before oocyte insemination. CRISPR J. 4, 132\u2013146 (2021)","journal-title":"CRISPR J."},{"key":"12_CR190","doi-asserted-by":"crossref","unstructured":"Oseguera-L\u00f3pez, I., P\u00e9rez-Cerezales, S., Ortiz-S\u00e1nchez, P.B., Mondragon-Payne, O., S\u00e1nchez-S\u00e1nchez, R., Jim\u00e9nez-Morales, I., Fierro, R., Gonz\u00e1lez-M\u00e1rquez, H.: Perfluorooctane sulfonate (PFOS) and Perfluorohexane sulfonate (PFHxS) alters protein phosphorylation, increase ROS levels and DNA fragmentation during in vitro capacitation of boar spermatozoa. Animals (Basel). 10 (2020)","DOI":"10.3390\/ani10101934"},{"key":"12_CR191","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.theriogenology.2021.01.015","volume":"164","author":"J Pang","year":"2021","unstructured":"Pang, J., Yang, H., Feng, X., Wang, Q., Cai, Y., Liu, Z., Wang, C., Wang, F., Zhang, Y.: HT-2 toxin affects cell viability of goat spermatogonial stem cells through AMPK-ULK1 autophagy pathways. Theriogenology. 164, 22\u201330 (2021)","journal-title":"Theriogenology"},{"key":"12_CR192","doi-asserted-by":"publisher","first-page":"632","DOI":"10.56093\/ijans.v89i6.91114","volume":"89","author":"N Chand","year":"2019","unstructured":"Chand, N., Tyagi, S., Prasad, R., Dutta, D., Sirohi, A.S., Sharma, A., Tyagi, R.: Effect of heavy metals on oxidative markers and semen quality parameters in HF crossbred bulls. Indian J. Anim. Sci. 89, 632\u2013636 (2019)","journal-title":"Indian J. Anim. Sci."},{"key":"12_CR193","doi-asserted-by":"publisher","first-page":"9502","DOI":"10.3168\/jds.2019-18089","volume":"103","author":"N Llamas-Luce\u00f1o","year":"2020","unstructured":"Llamas-Luce\u00f1o, N., Hostens, M., Mullaart, E., Broekhuijse, M., Lonergan, P., Van Soom, A.: High temperature-humidity index compromises sperm quality and fertility of Holstein bulls in temperate climates. J. Dairy Sci. 103, 9502\u20139514 (2020)","journal-title":"J. Dairy Sci."},{"key":"12_CR194","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1016\/j.theriogenology.2020.01.014","volume":"144","author":"GR Pereira","year":"2020","unstructured":"Pereira, G.R., de Lazari, F.L., Dalberto, P.F., Bizarro, C.V., Sontag, E.R., Koetz Junior, C., Menegassi, S.R.O., Barcellos, J.O.J., Bustamante-Filho, I.C.: Effect of scrotal insulation on sperm quality and seminal plasma proteome of Brangus bulls. Theriogenology. 144, 194\u2013203 (2020)","journal-title":"Theriogenology"},{"key":"12_CR195","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s11250-020-02516-y","volume":"53","author":"ST Pe\u00f1a Jr","year":"2021","unstructured":"Pe\u00f1a Jr., S.T., Stone, F., Gummow, B., Parker, A.J., Paris, D.: Susceptibility of boar spermatozoa to heat stress using in vivo and in vitro experimental models. Trop. Anim. Health Prod. 53, 97 (2021)","journal-title":"Trop. Anim. Health Prod."},{"key":"12_CR196","doi-asserted-by":"publisher","first-page":"txac001","DOI":"10.1093\/tas\/txac001","volume":"6","author":"TD Harrison","year":"2022","unstructured":"Harrison, T.D., Chaney, E.M., Brandt, K.J., Ault-Seay, T.B., Schneider, L.G., Strickland, L.G., Schrick, F.N., McLean, K.J.: The effects of differing nutritional levels and body condition score on scrotal circumference, motility, and morphology of bovine sperm. Transl. Anim. Sci. 6, txac001 (2022)","journal-title":"Transl. Anim. Sci."},{"key":"12_CR197","doi-asserted-by":"publisher","first-page":"272","DOI":"10.1016\/j.rbmo.2010.11.020","volume":"22","author":"C Kennedy","year":"2011","unstructured":"Kennedy, C., Ahlering, P., Rodriguez, H., Levy, S., Sutovsky, P.: Sperm chromatin structure correlates with spontaneous abortion and multiple pregnancy rates in assisted reproduction. Reprod. Biomed. Online. 22, 272\u2013276 (2011)","journal-title":"Reprod. Biomed. Online"},{"key":"12_CR198","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1080\/19396368.2020.1801889","volume":"66","author":"P Ahlering","year":"2020","unstructured":"Ahlering, P., Sutovsky, M., Gliedt, D., Branson, K., Miranda Vizuete, A., Sutovsky, P.: Sperm content of TXNDC8 reflects sperm chromatin structure, pregnancy establishment, and incidence of multiple births after ART. Syst Biol Reprod Med. 66, 311\u2013321 (2020)","journal-title":"Syst Biol Reprod Med"},{"key":"12_CR199","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/j.theriogenology.2020.01.065","volume":"150","author":"M Rubessa","year":"2020","unstructured":"Rubessa, M., Wheeler, M.B.: Label-free microscopy: a non-invasive new tool to assess gametes and embryo quality. Theriogenology. 150, 241\u2013246 (2020)","journal-title":"Theriogenology"},{"key":"12_CR200","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.rbmo.2020.03.011","volume":"41","author":"F Sharara","year":"2020","unstructured":"Sharara, F., Seaman, E., Morris, R., Schinfeld, J., Nichols, J., Sobel, M., Lee, A., Somkuti, S., Hirshberg, S., Budinetz, T., Barmat, L., Palermo, G., et al.: Multicentric, prospective observational data show sperm capacitation predicts male fertility, and cohort comparison reveals a high prevalence of impaired capacitation in men questioning their fertility. Reprod. Biomed. Online. 41, 69\u201379 (2020)","journal-title":"Reprod. Biomed. Online"},{"key":"12_CR201","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.theriogenology.2019.03.011","volume":"131","author":"D Blommaert","year":"2019","unstructured":"Blommaert, D., Sergeant, N., Delehedde, M., Jouy, N., Mitchell, V., Franck, T., Donnay, I., Lejeune, J.P., Serteyn, D.: Expression, localization, and concentration of A-kinase anchor protein 4 (AKAP4) and its precursor (proAKAP4) in equine semen: promising marker correlated to the total and progressive motility in thawed spermatozoa. Theriogenology. 131, 52\u201360 (2019)","journal-title":"Theriogenology"},{"key":"12_CR202","doi-asserted-by":"crossref","unstructured":"Kerns, K., Zigo, M., Sutovsky, P.: Zinc: a necessary ion for mammalian sperm fertilization competency. Int. J. Mol. Sci., 19 (2018)","DOI":"10.20944\/preprints201811.0425.v1"},{"key":"12_CR203","doi-asserted-by":"crossref","unstructured":"Lawlor, M., Zigo, M., Kerns, K., Cho, I.K., Easley Iv, C.A., Sutovsky, P.: Spermatozoan metabolism as a non-traditional model for the study of Huntington's disease. Int. J. Mol. Sci. 23 (2022)","DOI":"10.3390\/ijms23137163"},{"key":"12_CR204","doi-asserted-by":"publisher","first-page":"244","DOI":"10.3109\/19396360903056224","volume":"55","author":"C Buckman","year":"2009","unstructured":"Buckman, C., George, T.C., Friend, S., Sutovsky, M., Miranda-Vizuete, A., Ozanon, C., Morrissey, P., Sutovsky, P.: High throughput, parallel imaging and biomarker quantification of human spermatozoa by ImageStream flow cytometry. Syst. Biol. Reprod. Med. 55, 244\u2013251 (2009)","journal-title":"Syst. Biol. Reprod. Med."},{"key":"12_CR205","first-page":"CD010167","volume":"2","author":"DM Teixeira","year":"2020","unstructured":"Teixeira, D.M., Hadyme Miyague, A., Barbosa, M.A., Navarro, P.A., Raine-Fenning, N., Nastri, C.O., Martins, W.P.: Regular (ICSI) versus ultra-high magnification (IMSI) sperm selection for assisted reproduction. Cochrane Database Syst. Rev. 2, CD010167 (2020)","journal-title":"Cochrane Database Syst. Rev."},{"key":"12_CR206","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2023.05.009","volume":"47","author":"N Costa-Borges","year":"2023","unstructured":"Costa-Borges, N., Munne, S., Albo, E., Mas, S., Castello, C., Giralt, G., Lu, Z., Chau, C., Acacio, M., Mestres, E., Matia, Q., Marques, L., et al.: First babies conceived with automated intracytoplasmic sperm injection. Reprod. Biomed. Online. 47, 103237 (2023)","journal-title":"Reprod. Biomed. Online"},{"key":"12_CR207","doi-asserted-by":"publisher","first-page":"6334","DOI":"10.1073\/pnas.1220910110","volume":"110","author":"EL Miles","year":"2013","unstructured":"Miles, E.L., O'Gorman, C., Zhao, J., Samuel, M., Walters, E., Yi, Y.J., Sutovsky, M., Prather, R.S., Wells, K.D., Sutovsky, P.: Transgenic pig carrying green fluorescent proteasomes. Proc. Natl. Acad. Sci. USA. 110, 6334\u20136339 (2013)","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"12_CR208","doi-asserted-by":"publisher","first-page":"12583","DOI":"10.1038\/s41598-019-49024-0","volume":"9","author":"M Zigo","year":"2019","unstructured":"Zigo, M., Manaskova-Postlerova, P., Jonakova, V., Kerns, K., Sutovsky, P.: Compartmentalization of the proteasome-interacting proteins during sperm capacitation. Sci. Rep. 9, 12583 (2019)","journal-title":"Sci. Rep."},{"key":"12_CR209","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1111\/j.1365-2605.2011.01217.x","volume":"35","author":"YJ Yi","year":"2012","unstructured":"Yi, Y.J., Zimmerman, S.W., Manandhar, G., Odhiambo, J.F., Kennedy, C., Jonakova, V., Manaskova-Postlerova, P., Sutovsky, M., Park, C.S., Sutovsky, P.: Ubiquitin-activating enzyme (UBA1) is required for sperm capacitation, acrosomal exocytosis and sperm-egg coat penetration during porcine fertilization. Int. J. Androl. 35, 196\u2013210 (2012)","journal-title":"Int. J. Androl."},{"key":"12_CR210","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.jri.2009.11.002","volume":"84","author":"YJ Yi","year":"2010","unstructured":"Yi, Y.J., Manandhar, G., Sutovsky, M., Jonakova, V., Park, C.S., Sutovsky, P.: Inhibition of 19S proteasomal regulatory complex subunit PSMD8 increases polyspermy during porcine fertilization in vitro. J. Reprod. Immunol. 84, 154\u2013163 (2010)","journal-title":"J. Reprod. Immunol."},{"key":"12_CR211","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1095\/biolreprod.107.061275","volume":"77","author":"YJ Yi","year":"2007","unstructured":"Yi, Y.J., Manandhar, G., Sutovsky, M., Li, R., Jonakova, V., Oko, R., Park, C.S., Prather, R.S., Sutovsky, P.: Ubiquitin C-terminal hydrolase-activity is involved in sperm acrosomal function and anti-polyspermy defense during porcine fertilization. Biol. Reprod. 77, 780\u2013793 (2007)","journal-title":"Biol. Reprod."},{"key":"12_CR212","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1095\/biolreprod.102.010975","volume":"69","author":"WE Thompson","year":"2003","unstructured":"Thompson, W.E., Ramalho-Santos, J., Sutovsky, P.: Ubiquitination of prohibitin in mammalian sperm mitochondria: possible roles in the regulation of mitochondrial inheritance and sperm quality control. Biol. Reprod. 69, 254\u2013260 (2003)","journal-title":"Biol. Reprod."},{"key":"12_CR213","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1002\/jcp.21528","volume":"217","author":"J Antelman","year":"2008","unstructured":"Antelman, J., Manandhar, G., Yi, Y.J., Li, R., Whitworth, K.M., Sutovsky, M., Agca, C., Prather, R.S., Sutovsky, P.: Expression of mitochondrial transcription factor A (TFAM) during porcine gametogenesis and preimplantation embryo development. J. Cell. Physiol. 217, 529\u2013543 (2008)","journal-title":"J. Cell. Physiol."},{"key":"12_CR214","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068873","volume":"8","author":"P Hillman","year":"2013","unstructured":"Hillman, P., Ickowicz, D., Vizel, R., Breitbart, H.: Dissociation between AKAP3 and PKARII promotes AKAP3 degradation in sperm capacitation. PLoS One. 8, e68873 (2013)","journal-title":"PLoS One"},{"key":"12_CR215","doi-asserted-by":"publisher","DOI":"10.1016\/j.anireprosci.2022.107079","volume":"247","author":"X Qu","year":"2022","unstructured":"Qu, X., Han, Y., Chen, X., Lv, Y., Zhang, Y., Cao, L., Zhang, J., Jin, Y.: Inhibition of 26S proteasome enhances AKAP3-mediated cAMP-PKA signaling during boar sperm capacitation. Anim. Reprod. Sci. 247, 107079 (2022)","journal-title":"Anim. Reprod. Sci."},{"key":"12_CR216","doi-asserted-by":"crossref","unstructured":"Zapata-Carmona, H., Bar\u00f3n, L., Kong, M., Morales, P.: Protein kinase a (PRKA) activity is regulated by the proteasome at the onset of human sperm capacitation. Cells. 10 (2021)","DOI":"10.3390\/cells10123501"}],"container-title":["Advances in Experimental Medicine and Biology","Molecular Male Reproductive Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-031-82990-1_12","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T17:03:31Z","timestamp":1745946211000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-031-82990-1_12"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"ISBN":["9783031829895","9783031829901"],"references-count":216,"URL":"https:\/\/doi.org\/10.1007\/978-3-031-82990-1_12","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"30 April 2025","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}