{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T07:50:43Z","timestamp":1782978643590,"version":"3.54.5"},"publisher-location":"Cham","reference-count":87,"publisher":"Springer Nature Switzerland","isbn-type":[{"value":"9783031879180","type":"print"},{"value":"9783031879197","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"DOI":"10.1007\/978-3-031-87919-7_16","type":"book-chapter","created":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T17:52:08Z","timestamp":1749664328000},"page":"457-472","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Oligodendroglia in Neuromyelitis Optica Spectrum Disorder"],"prefix":"10.1007","author":[{"given":"Ai","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuzhen","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexei","family":"Verkhratsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fu-Dong","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,6,12]]},"reference":[{"key":"16_CR1","doi-asserted-by":"publisher","first-page":"4278","DOI":"10.1002\/anie.200460804","volume":"43","author":"P Agre","year":"2004","unstructured":"Agre, P. (2004). Aquaporin water channels (Nobel Lecture). Angewandte Chemie (International Ed. in English), 43, 4278\u20134290.","journal-title":"Angewandte Chemie (International Ed. in English)"},{"key":"16_CR2","doi-asserted-by":"publisher","first-page":"3220","DOI":"10.1523\/JNEUROSCI.3780-05.2006","volume":"26","author":"E Alberdi","year":"2006","unstructured":"Alberdi, E., S\u00e1nchez-G\u00f3mez, M. V., Torre, I., Domercq, M., P\u00e9rez-Samart\u00edn, A., P\u00e9rez-Cerd\u00e1, F., & Matute, C. (2006). Activation of kainate receptors sensitizes oligodendrocytes to complement attack. The Journal of Neuroscience, 26, 3220\u20133228.","journal-title":"The Journal of Neuroscience"},{"key":"16_CR3","doi-asserted-by":"publisher","first-page":"2106","DOI":"10.1073\/pnas.0437946100","volume":"100","author":"M Amiry-Moghaddam","year":"2003","unstructured":"Amiry-Moghaddam, M., Otsuka, T., Hurn, P. D., Traystman, R. J., Haug, F. M., Froehner, S. C., Adams, M. E., Neely, J. D., Agre, P., Ottersen, O. P., et al. (2003). An alpha-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain. Proceedings of the National Academy of Sciences of the United States of America, 100, 2106\u20132111.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"16_CR4","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2022.102331","volume":"217","author":"JV Andersen","year":"2022","unstructured":"Andersen, J. V., Schousboe, A., & Verkhratsky, A. (2022). Astrocyte energy and neurotransmitter metabolism in Alzheimer's disease: Integration of the glutamate\/GABA-glutamine cycle. Progress in Neurobiology, 217, 102331.","journal-title":"Progress in Neurobiology"},{"key":"16_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/1098-1136(200010)32:1<1::AID-GLIA10>3.0.CO;2-W","volume":"32","author":"CM Anderson","year":"2000","unstructured":"Anderson, C. M., & Swanson, R. A. (2000). Astrocyte glutamate transport: Review of properties, regulation, and physiological functions. Glia, 32, 1\u201314.","journal-title":"Glia"},{"key":"16_CR6","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1002\/ana.21802","volume":"66","author":"JL Bennett","year":"2009","unstructured":"Bennett, J. L., Lam, C., Kalluri, S. R., Saikali, P., Bautista, K., Dupree, C., Glogowska, M., Case, D., Antel, J. P., Owens, G. P., et al. (2009). Intrathecal pathogenic anti\u2013aquaporin-4 antibodies in early neuromyelitis optica. Annals of Neurology, 66, 617\u2013629.","journal-title":"Annals of Neurology"},{"key":"16_CR7","doi-asserted-by":"publisher","first-page":"17005","DOI":"10.1038\/celldisc.2017.5","volume":"3","author":"AC Boulay","year":"2017","unstructured":"Boulay, A. C., Saubam\u00e9a, B., Adam, N., Chasseigneaux, S., Mazar\u00e9, N., Gilbert, A., Bahin, M., Bastianelli, L., Blugeon, C., Perrin, S., et al. (2017). Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface. Cell Discovery, 3, 17005.","journal-title":"Cell Discovery"},{"key":"16_CR8","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1159\/000463061","volume":"70 Suppl 1","author":"D Brown","year":"2017","unstructured":"Brown, D. (2017). The discovery of water channels (Aquaporins). Annals of Nutrition & Metabolism, 70 Suppl 1, 37\u201342.","journal-title":"Annals of Nutrition & Metabolism"},{"key":"16_CR9","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/j.autrev.2018.01.001","volume":"17","author":"A Bruscolini","year":"2018","unstructured":"Bruscolini, A., Sacchetti, M., La Cava, M., Gharbiya, M., Ralli, M., Lambiase, A., De Virgilio, A., & Greco, A. (2018). Diagnosis and management of neuromyelitis optica spectrum disorders \u2013 An update. Autoimmunity Reviews, 17, 195\u2013200.","journal-title":"Autoimmunity Reviews"},{"key":"16_CR10","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1038\/nri2529","volume":"9","author":"B Diamond","year":"2009","unstructured":"Diamond, B., Huerta, P. T., Mina-Osorio, P., Kowal, C., & Volpe, B. T. (2009). Losing your nerves? Maybe it's the antibodies. Nature Reviews. Immunology, 9, 449\u2013456.","journal-title":"Nature Reviews. Immunology"},{"key":"16_CR11","first-page":"434","volume-title":"My\u00e9lite aigu\u00eb dorso-lombaire avec n\u00e9vrite optique","author":"E Devic","year":"1895","unstructured":"Devic, E. (1895). My\u00e9lite aigu\u00eb dorso-lombaire avec n\u00e9vrite optique (Vol. 1895, pp. 434\u2013439). Autopsie, Congr\u00e8s fran\u00e7ais de medicine, Asselin et Houzeau, Louis Savy, Paris, Lyon."},{"key":"16_CR12","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1038\/aps.2009.24","volume":"30","author":"XX Dong","year":"2009","unstructured":"Dong, X. X., Wang, Y., & Qin, Z. H. (2009). Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases. Acta Pharmacologica Sinica, 30, 379\u2013387.","journal-title":"Acta Pharmacologica Sinica"},{"key":"16_CR14","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1186\/s12974-018-1333-z","volume":"15","author":"T Duan","year":"2018","unstructured":"Duan, T., Smith, A. J., & Verkman, A. S. (2018). Complement-dependent bystander injury to neurons in AQP4-IgG seropositive neuromyelitis optica. Journal of Neuroinflammation, 15, 294.","journal-title":"Journal of Neuroinflammation"},{"key":"16_CR15","doi-asserted-by":"crossref","unstructured":"Duan, T., Smith, A. J., & Verkman, A. S. (2019). Complement-independent bystander injury in AQP4-IgG seropositive neuromyelitis optica produced by antibody-dependent cellular cytotoxicity. Acta Neuropathologica Communications, 7.","DOI":"10.1186\/s40478-019-0766-7"},{"key":"16_CR16","doi-asserted-by":"publisher","first-page":"1118","DOI":"10.1006\/bbrc.2000.3505","volume":"276","author":"M Elkjaer","year":"2000","unstructured":"Elkjaer, M., Vajda, Z., Nejsum, L. N., Kwon, T., Jensen, U. B., Amiry-Moghaddam, M., Fr\u00f8kiaer, J., & Nielsen, S. (2000). Immunolocalization of AQP9 in liver, epididymis, testis, spleen, and brain. Biochemical and Biophysical Research Communications, 276, 1118\u20131128.","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"16_CR17","doi-asserted-by":"publisher","first-page":"2143","DOI":"10.1523\/JNEUROSCI.3547-03.2004","volume":"24","author":"JR Faulkner","year":"2004","unstructured":"Faulkner, J. R., Herrmann, J. E., Woo, M. J., Tansey, K. E., Doan, N. B., & Sofroniew, M. V. (2004). Reactive astrocytes protect tissue and preserve function after spinal cord injury. The Journal of Neuroscience, 24, 2143\u20132155.","journal-title":"The Journal of Neuroscience"},{"key":"16_CR18","doi-asserted-by":"crossref","unstructured":"Filosa, J. A. (2010). Vascular tone and neurovascular coupling: considerations toward an improved in vitro model. Frontiers in Neuroenergetics, 2.","DOI":"10.3389\/fnene.2010.00016"},{"key":"16_CR19","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1038\/nature11007","volume":"485","author":"U F\u00fcnfschilling","year":"2012","unstructured":"F\u00fcnfschilling, U., Supplie, L. M., Mahad, D., Boretius, S., Saab, A. S., Edgar, J., Brinkmann, B. G., Kassmann, C. M., Tzvetanova, I. D., M\u00f6bius, W., et al. (2012). Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity. Nature, 485, 517\u2013521.","journal-title":"Nature"},{"key":"16_CR20","volume-title":"De la neuromy\u00e9lite optique aigu?","author":"F Gault","year":"1894","unstructured":"Gault, F. (1894). De la neuromy\u00e9lite optique aigu? Th\u00e9se: Facult\u00e9 de M\u00e9decine et de Pharmacie."},{"key":"16_CR21","doi-asserted-by":"crossref","unstructured":"G\u00f3mez-Pinedo, U., Garc\u00eda-\u00c1vila, Y., Gallego-Villarejo, L., Mat\u00edas-Guiu, J. A., Benito-Mart\u00edn, M. S., Esteban-Garc\u00eda, N., Sanclemente-Alam\u00e1n, I., Pytel, V., Moreno-Jim\u00e9nez, L., Sancho-Bielsa, F., et al. (2021). Sera from patients with NMOSD reduce the differentiation capacity of precursor cells in the central nervous system. International Journal of Molecular Sciences, 22.","DOI":"10.3390\/ijms22105192"},{"key":"16_CR22","doi-asserted-by":"publisher","first-page":"1302","DOI":"10.1002\/glia.23306","volume":"66","author":"YE Guo","year":"2018","unstructured":"Guo, Y. E., Suo, N., Cui, X., Yuan, Q., & Xie, X. (2018). Vitamin C promotes oligodendrocytes generation and remyelination. Glia, 66, 1302\u20131316.","journal-title":"Glia"},{"key":"16_CR23","doi-asserted-by":"publisher","first-page":"2473","DOI":"10.1084\/jem.20081241","volume":"205","author":"SR Hinson","year":"2008","unstructured":"Hinson, S. R., Roemer, S. F., Lucchinetti, C. F., Fryer, J. P., Kryzer, T. J., Chamberlain, J. L., Howe, C. L., Pittock, S. J., & Lennon, V. A. (2008). Aquaporin-4-binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2. The Journal of Experimental Medicine, 205, 2473\u20132481.","journal-title":"The Journal of Experimental Medicine"},{"key":"16_CR24","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2022.110599","volume":"39","author":"L H\u00f6sli","year":"2022","unstructured":"H\u00f6sli, L., Zuend, M., Bredell, G., Zanker, H. S., Porto de Oliveira, C. E., Saab, A. S., & Weber, B. (2022). Direct vascular contact is a hallmark of cerebral astrocytes. Cell Reports, 39, 110599.","journal-title":"Cell Reports"},{"key":"16_CR25","doi-asserted-by":"crossref","unstructured":"Hubbard, J. A., Hsu, M. S., Seldin, M. M., & Binder, D. K. (2015). Expression of the astrocyte water channel aquaporin-4 in the mouse brain. ASN Neuro, 7.","DOI":"10.1177\/1759091415605486"},{"key":"16_CR26","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1038\/s41572-020-0214-9","volume":"6","author":"S Jarius","year":"2020","unstructured":"Jarius, S., Paul, F., Weinshenker, B. G., Levy, M., Kim, H. J., & Wildemann, B. (2020). Neuromyelitis optica. Nature Reviews Disease Primers, 6, 85.","journal-title":"Nature Reviews Disease Primers"},{"key":"16_CR27","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/1742-2094-9-14","volume":"9","author":"S Jarius","year":"2012","unstructured":"Jarius, S., Ruprecht, K., Wildemann, B., Kuempfel, T., Ringelstein, M., Geis, C., Kleiter, I., Kleinschnitz, C., Berthele, A., Brettschneider, J., et al. (2012). Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients. Journal of Neuroinflammation, 9, 14.","journal-title":"Journal of Neuroinflammation"},{"key":"16_CR28","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1038\/nrneurol.2010.72","volume":"6","author":"S Jarius","year":"2010","unstructured":"Jarius, S., & Wildemann, B. (2010). AQP4 antibodies in neuromyelitis optica: Diagnostic and pathogenetic relevance. Nature Reviews Neurology, 6, 383\u2013392.","journal-title":"Nature Reviews Neurology"},{"key":"16_CR29","doi-asserted-by":"publisher","first-page":"1354","DOI":"10.1007\/s00415-011-6355-8","volume":"259","author":"S Jarius","year":"2012","unstructured":"Jarius, S., & Wildemann, B. (2012). The case of the Marquis de Causan (1804): An early account of visual loss associated with spinal cord inflammation. Journal of Neurology, 259, 1354\u20131357.","journal-title":"Journal of Neurology"},{"key":"16_CR30","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1111\/bpa.12084","volume":"23","author":"S Jarius","year":"2013","unstructured":"Jarius, S., & Wildemann, B. (2013a). Aquaporin-4 antibodies (NMO-IgG) as a serological marker of neuromyelitis optica: A critical review of the literature. Brain Pathology, 23, 661\u2013683.","journal-title":"Brain Pathology"},{"key":"16_CR31","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/1742-2094-10-8","volume":"10","author":"S Jarius","year":"2013","unstructured":"Jarius, S., & Wildemann, B. (2013b). The history of neuromyelitis optica. Journal of Neuroinflammation, 10, 8.","journal-title":"Journal of Neuroinflammation"},{"key":"16_CR32","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1186\/s12974-019-1594-1","volume":"16","author":"S Jarius","year":"2019","unstructured":"Jarius, S., & Wildemann, B. (2019). The history of neuromyelitis optica. Part 2: 'Spinal amaurosis', or how it all began. Journal of Neuroinflammation, 16, 280.","journal-title":"Journal of Neuroinflammation"},{"key":"16_CR33","doi-asserted-by":"publisher","first-page":"4029","DOI":"10.1242\/jcs.035758","volume":"121","author":"H Kong","year":"2008","unstructured":"Kong, H., Fan, Y., Xie, J., Ding, J., Sha, L., Shi, X., Sun, X., & Hu, G. (2008). AQP4 knockout impairs proliferation, migration and neuronal differentiation of adult neural stem cells. Journal of Cell Science, 121, 4029\u20134036.","journal-title":"Journal of Cell Science"},{"key":"16_CR34","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-70420-8","volume-title":"General histology of the mammal","author":"R Krstic","year":"1985","unstructured":"Krstic, R. (1985). General histology of the mammal. Springer."},{"key":"16_CR35","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1042\/BC20040153","volume":"98","author":"CA La Porta","year":"2006","unstructured":"La Porta, C. A., Gena, P., Gritti, A., Fascio, U., Svelto, M., & Calamita, G. (2006). Adult murine CNS stem cells express aquaporin channels. Biology of the Cell, 98, 89\u201394.","journal-title":"Biology of the Cell"},{"key":"16_CR36","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1084\/jem.20050304","volume":"202","author":"VA Lennon","year":"2005","unstructured":"Lennon, V. A., Kryzer, T. J., Pittock, S. J., Verkman, A. S., & Hinson, S. R. (2005). IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. The Journal of Experimental Medicine, 202, 473\u2013477.","journal-title":"The Journal of Experimental Medicine"},{"key":"16_CR37","doi-asserted-by":"publisher","first-page":"2106","DOI":"10.1016\/S0140-6736(04)17551-X","volume":"364","author":"VA Lennon","year":"2004","unstructured":"Lennon, V. A., Wingerchuk, D. M., Kryzer, T. J., Pittock, S. J., Lucchinetti, C. F., Fujihara, K., Nakashima, I., & Weinshenker, B. G. (2004). A serum autoantibody marker of neuromyelitis optica: Distinction from multiple sclerosis. Lancet, 364, 2106\u20132112.","journal-title":"Lancet"},{"key":"16_CR38","doi-asserted-by":"publisher","first-page":"2575","DOI":"10.1002\/glia.23512","volume":"66","author":"Y Liu","year":"2018","unstructured":"Liu, Y., Given, K. S., Owens, G. P., Macklin, W. B., & Bennett, J. L. (2018). Distinct patterns of glia repair and remyelination in antibody-mediated demyelination models of multiple sclerosis and neuromyelitis optica. Glia, 66, 2575\u20132588.","journal-title":"Glia"},{"key":"16_CR39","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1186\/s12974-016-0767-4","volume":"13","author":"Y Liu","year":"2016","unstructured":"Liu, Y., Harlow, D. E., Given, K. S., Owens, G. P., Macklin, W. B., & Bennett, J. L. (2016). Variable sensitivity to complement-dependent cytotoxicity in murine models of neuromyelitis optica. Journal of Neuroinflammation, 13, 301.","journal-title":"Journal of Neuroinflammation"},{"key":"16_CR40","doi-asserted-by":"publisher","first-page":"1450","DOI":"10.1093\/brain\/awf151","volume":"125","author":"CF Lucchinetti","year":"2002","unstructured":"Lucchinetti, C. F., Mandler, R. N., McGavern, D., Bruck, W., Gleich, G., Ransohoff, R. M., Trebst, C., Weinshenker, B., Wingerchuk, D., Parisi, J. E., et al. (2002). A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica. Brain, 125, 1450\u20131461.","journal-title":"Brain"},{"key":"16_CR41","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1002\/glia.24271","volume":"71","author":"W Luo","year":"2022","unstructured":"Luo, W., Xu, H., Xu, L., Jiang, W., Chen, C., Chang, Y., Liu, C., Tian, Z., Qiu, X., Xie, C., et al. (2022). Remyelination in neuromyelitis optica spectrum disorder is promoted by edaravone through mTORC1 signaling activation. Glia, 71, 284\u2013304.","journal-title":"Glia"},{"key":"16_CR42","doi-asserted-by":"crossref","unstructured":"MacVicar, B. A., & Newman, E. A. (2015). Astrocyte regulation of blood flow in the brain. Cold Spring Harbor Perspectives in Biology, 7.","DOI":"10.1101\/cshperspect.a020388"},{"key":"16_CR43","doi-asserted-by":"publisher","first-page":"2578","DOI":"10.1093\/brain\/awq177","volume":"133","author":"R Marignier","year":"2010","unstructured":"Marignier, R., Nicolle, A., Watrin, C., Touret, M., Cavagna, S., Varrin-Doyer, M., Cavillon, G., Rogemond, V., Confavreux, C., Honnorat, J., et al. (2010). Oligodendrocytes are damaged by neuromyelitis optica immunoglobulin G via astrocyte injury. Brain, 133, 2578\u20132591.","journal-title":"Brain"},{"key":"16_CR44","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/S0166-2236(00)01746-X","volume":"24","author":"C Matute","year":"2001","unstructured":"Matute, C., Alberdi, E., Domercq, M., P\u00e9rez-Cerd\u00e1, F., P\u00e9rez-Samart\u00edn, A., & S\u00e1nchez-G\u00f3mez, M. V. (2001). The link between excitotoxic oligodendroglial death and demyelinating diseases. Trends in Neurosciences, 24, 224\u2013230.","journal-title":"Trends in Neurosciences"},{"key":"16_CR45","doi-asserted-by":"crossref","unstructured":"Mestre, H., Hablitz, L. M., Xavier, A. L., Feng, W., Zou, W., Pu, T., Monai, H., Murlidharan, G., Castellanos Rivera, R. M., Simon, M. J., et al. (2018). Aquaporin-4-dependent glymphatic solute transport in the rodent brain. eLife, 7.","DOI":"10.7554\/eLife.40070"},{"key":"16_CR46","doi-asserted-by":"publisher","first-page":"1224","DOI":"10.1093\/brain\/awm047","volume":"130","author":"T Misu","year":"2007","unstructured":"Misu, T., Fujihara, K., Kakita, A., Konno, H., Nakamura, M., Watanabe, S., Takahashi, T., Nakashima, I., Takahashi, H., & Itoyama, Y. (2007). Loss of aquaporin 4 in lesions of neuromyelitis optica: Distinction from multiple sclerosis. Brain, 130, 1224\u20131234.","journal-title":"Brain"},{"key":"16_CR47","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1007\/s00401-013-1116-7","volume":"125","author":"T Misu","year":"2013","unstructured":"Misu, T., H\u00f6ftberger, R., Fujihara, K., Wimmer, I., Takai, Y., Nishiyama, S., Nakashima, I., Konno, H., Bradl, M., Garzuly, F., et al. (2013). Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica. Acta Neuropathologica, 125, 815\u2013827.","journal-title":"Acta Neuropathologica"},{"key":"16_CR48","doi-asserted-by":"publisher","first-page":"1910","DOI":"10.1002\/glia.23814","volume":"68","author":"N Miyamoto","year":"2020","unstructured":"Miyamoto, N., Magami, S., Inaba, T., Ueno, Y., Hira, K., Kijima, C., Nakajima, S., Yamashiro, K., Urabe, T., & Hattori, N. (2020). The effects of A1\/A2 astrocytes on oligodendrocyte linage cells against white matter injury under prolonged cerebral hypoperfusion. Glia, 68, 1910\u20131924.","journal-title":"Glia"},{"key":"16_CR49","doi-asserted-by":"publisher","first-page":"3372","DOI":"10.1038\/s41467-023-39046-8","volume":"14","author":"I Molina-Gonzalez","year":"2023","unstructured":"Molina-Gonzalez, I., Holloway, R. K., Jiwaji, Z., Dando, O., Kent, S. A., Emelianova, K., Lloyd, A. F., Forbes, L. H., Mahmood, A., Skripuletz, T., et al. (2023). Astrocyte-oligodendrocyte interaction regulates central nervous system regeneration. Nature Communications, 14, 3372.","journal-title":"Nature Communications"},{"key":"16_CR50","doi-asserted-by":"publisher","first-page":"1543","DOI":"10.1152\/physrev.00011.2013","volume":"93","author":"EA Nagelhus","year":"2013","unstructured":"Nagelhus, E. A., & Ottersen, O. P. (2013). Physiological roles of aquaporin-4 in brain. Physiological Reviews, 93, 1543\u20131562.","journal-title":"Physiological Reviews"},{"key":"16_CR51","doi-asserted-by":"publisher","first-page":"2702","DOI":"10.1007\/s00018-008-8059-5","volume":"65","author":"A Nair","year":"2008","unstructured":"Nair, A., Frederick, T. J., & Miller, S. D. (2008). Astrocytes in multiple sclerosis: A product of their environment. Cellular and Molecular Life Sciences, 65, 2702\u20132720.","journal-title":"Cellular and Molecular Life Sciences"},{"key":"16_CR52","doi-asserted-by":"publisher","first-page":"14108","DOI":"10.1073\/pnas.241508198","volume":"98","author":"JD Neely","year":"2001","unstructured":"Neely, J. D., Amiry-Moghaddam, M., Ottersen, O. P., Froehner, S. C., Agre, P., & Adams, M. E. (2001). Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein. Proceedings of the National Academy of Sciences of the United States of America, 98, 14108\u201314113.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"16_CR53","doi-asserted-by":"publisher","first-page":"13949","DOI":"10.1523\/JNEUROSCI.3395-07.2007","volume":"27","author":"JL Orthmann-Murphy","year":"2007","unstructured":"Orthmann-Murphy, J. L., Freidin, M., Fischer, E., Scherer, S. S., & Abrams, C. K. (2007). Two distinct heterotypic channels mediate gap junction coupling between astrocyte and oligodendrocyte connexins. The Journal of Neuroscience, 27, 13949\u201313957.","journal-title":"The Journal of Neuroscience"},{"key":"16_CR54","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1016\/S1474-4422(12)70133-3","volume":"11","author":"MC Papadopoulos","year":"2012","unstructured":"Papadopoulos, M. C., & Verkman, A. S. (2012). Aquaporin 4 and neuromyelitis optica. The Lancet Neurology, 11, 535\u2013544.","journal-title":"The Lancet Neurology"},{"key":"16_CR55","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1038\/nrn3468","volume":"14","author":"MC Papadopoulos","year":"2013","unstructured":"Papadopoulos, M. C., & Verkman, A. S. (2013). Aquaporin water channels in the nervous system. Nature Reviews. Neuroscience, 14, 265\u2013277.","journal-title":"Nature Reviews. Neuroscience"},{"key":"16_CR56","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1212\/WNL.0000000000011153","volume":"96","author":"V Papp","year":"2021","unstructured":"Papp, V., Magyari, M., Aktas, O., Berger, T., Broadley, S. A., Cabre, P., Jacob, A., Kira, J. I., Leite, M. I., Marignier, R., et al. (2021). Worldwide incidence and prevalence of neuromyelitis optica: A systematic review. Neurology, 96, 59\u201377.","journal-title":"Neurology"},{"key":"16_CR57","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1177\/1352458510382324","volume":"16","author":"JD Parratt","year":"2010","unstructured":"Parratt, J. D., & Prineas, J. W. (2010). Neuromyelitis optica: A demyelinating disease characterized by acute destruction and regeneration of perivascular astrocytes. Multiple Sclerosis, 16, 1156\u20131172.","journal-title":"Multiple Sclerosis"},{"key":"16_CR59","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/0165-5728(93)90189-6","volume":"48","author":"SJ Piddlesden","year":"1993","unstructured":"Piddlesden, S. J., & Morgan, B. P. (1993). Killing of rat glial cells by complement: Deficiency of the rat analogue of CD59 is the cause of oligodendrocyte susceptibility to lysis. Journal of Neuroimmunology, 48, 169\u2013175.","journal-title":"Journal of Neuroimmunology"},{"key":"16_CR60","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1038\/s41582-021-00568-8","volume":"17","author":"SJ Pittock","year":"2021","unstructured":"Pittock, S. J., Zekeridou, A., & Weinshenker, B. G. (2021). Hope for patients with neuromyelitis optica spectrum disorders \u2013 From mechanisms to trials. Nature Reviews. Neurology, 17, 759\u2013773.","journal-title":"Nature Reviews. Neurology"},{"key":"16_CR61","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1126\/science.256.5055.385","volume":"256","author":"GM Preston","year":"1992","unstructured":"Preston, G. M., Carroll, T. P., Guggino, W. B., & Agre, P. (1992). Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein. Science, 256, 385\u2013387.","journal-title":"Science"},{"key":"16_CR62","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1097\/00005072-197004000-00002","volume":"29","author":"CS Raine","year":"1970","unstructured":"Raine, C. S., & Bornstein, M. B. (1970). Experimental allergic encephalomyelitis: An ultrastructural study of experimental demyelination in vitro. Journal of Neuropathology and Experimental Neurology, 29, 177\u2013191.","journal-title":"Journal of Neuropathology and Experimental Neurology"},{"key":"16_CR63","doi-asserted-by":"publisher","first-page":"11981","DOI":"10.1073\/pnas.95.20.11981","volume":"95","author":"JE Rash","year":"1998","unstructured":"Rash, J. E., Yasumura, T., Hudson, C. S., Agre, P., & Nielsen, S. (1998). Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord. Proceedings of the National Academy of Sciences of the United States of America, 95, 11981\u201311986.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"16_CR64","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1007\/s00401-013-1172-z","volume":"126","author":"J Ratelade","year":"2013","unstructured":"Ratelade, J., Asavapanumas, N., Ritchie, A. M., Wemlinger, S., Bennett, J. L., & Verkman, A. S. (2013). Involvement of antibody-dependent cell-mediated cytotoxicity in inflammatory demyelination in a mouse model of neuromyelitis optica. Acta Neuropathologica, 126, 699\u2013709.","journal-title":"Acta Neuropathologica"},{"key":"16_CR65","doi-asserted-by":"publisher","first-page":"2721","DOI":"10.1093\/brain\/awaa227","volume":"143","author":"C Richard","year":"2020","unstructured":"Richard, C., Ruiz, A., Cavagna, S., Bigotte, M., Vukusic, S., Masaki, K., Suenaga, T., Kira, J.-I., Giraudon, P., & Marignier, R. (2020). Connexins in neuromyelitis optica: A link between astrocytopathy and demyelination. Brain, 143, 2721\u20132732.","journal-title":"Brain"},{"key":"16_CR66","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.1093\/brain\/awl371","volume":"130","author":"SF Roemer","year":"2007","unstructured":"Roemer, S. F., Parisi, J. E., Lennon, V. A., Benarroch, E. E., Lassmann, H., Bruck, W., Mandler, R. N., Weinshenker, B. G., Pittock, S. J., Wingerchuk, D. M., et al. (2007). Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis. Brain, 130, 1194\u20131205.","journal-title":"Brain"},{"key":"16_CR67","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1093\/brain\/awp309","volume":"133","author":"S Saadoun","year":"2010","unstructured":"Saadoun, S., Waters, P., Bell, B. A., Vincent, A., Verkman, A. S., & Papadopoulos, M. C. (2010). Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice. Brain, 133, 349\u2013361.","journal-title":"Brain"},{"key":"16_CR68","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1111\/j.1440-1789.2007.00774.x","volume":"27","author":"J Satoh","year":"2007","unstructured":"Satoh, J., Tabunoki, H., Yamamura, T., Arima, K., & Konno, H. (2007). Human astrocytes express aquaporin-1 and aquaporin-4 in vitro and in vivo. Neuropathology, 27, 245\u2013256.","journal-title":"Neuropathology"},{"key":"16_CR69","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1007\/s00401-010-0704-z","volume":"120","author":"R Sharma","year":"2010","unstructured":"Sharma, R., Fischer, M.-T., Bauer, J., Felts, P. A., Smith, K. J., Misu, T., Fujihara, K., Bradl, M., & Lassmann, H. (2010). Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination. Acta Neuropathologica, 120, 223\u2013236.","journal-title":"Acta Neuropathologica"},{"key":"16_CR70","doi-asserted-by":"publisher","first-page":"1381","DOI":"10.1152\/physrev.00031.2018","volume":"99","author":"C Stadelmann","year":"2019","unstructured":"Stadelmann, C., Timmler, S., Barrantes-Freer, A., & Simons, M. (2019). Myelin in the central nervous system: Structure, function, and pathology. Physiological Reviews, 99, 1381\u20131431.","journal-title":"Physiological Reviews"},{"key":"16_CR71","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.neuron.2022.10.032","volume":"111","author":"Y Su","year":"2023","unstructured":"Su, Y., Wang, X., Yang, Y., Chen, L., Xia, W., Hoi, K. K., Li, H., Wang, Q., Yu, G., Chen, X., et al. (2023). Astrocyte endfoot formation controls the termination of oligodendrocyte precursor cell perivascular migration during development. Neuron, 111, 190\u2013201.e198.","journal-title":"Neuron"},{"key":"16_CR72","doi-asserted-by":"publisher","first-page":"2401","DOI":"10.1093\/brain\/awab102","volume":"144","author":"Y Takai","year":"2021","unstructured":"Takai, Y., Misu, T., Suzuki, H., Takahashi, T., Okada, H., Tanaka, S., Okita, K., Sasou, S., Watanabe, M., Namatame, C., et al. (2021). Staging of astrocytopathy and complement activation in neuromyelitis optica spectrum disorders. Brain, 144, 2401\u20132415.","journal-title":"Brain"},{"key":"16_CR73","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/s00401-017-1734-6","volume":"134","author":"L Tradtrantip","year":"2017","unstructured":"Tradtrantip, L., Yao, X., Su, T., Smith, A. J., & Verkman, A. S. (2017). Bystander mechanism for complement-initiated early oligodendrocyte injury in neuromyelitis optica. Acta Neuropathologica, 134, 35\u201344.","journal-title":"Acta Neuropathologica"},{"key":"16_CR74","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1126\/science.aad3839","volume":"351","author":"HH Tsai","year":"2016","unstructured":"Tsai, H. H., Niu, J., Munji, R., Davalos, D., Chang, J., Zhang, H., Tien, A. C., Kuo, C. J., Chan, J. R., Daneman, R., et al. (2016). Oligodendrocyte precursors migrate along vasculature in the developing nervous system. Science, 351, 379\u2013384.","journal-title":"Science"},{"key":"16_CR75","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1126\/science.1201954","volume":"332","author":"JM van den Elsen","year":"2011","unstructured":"van den Elsen, J. M., & Isenman, D. E. (2011). A crystal structure of the complex between human complement receptor 2 and its ligand C3d. Science, 332, 608\u2013611.","journal-title":"Science"},{"key":"16_CR76","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1111\/nyas.14917","volume":"1518","author":"A Verkhratsky","year":"2022","unstructured":"Verkhratsky, A., Arranz, A. M., Ciuba, K., & P\u0119kowska, A. (2022). Evolution of neuroglia. Annals of the New York Academy of Sciences, 1518, 120\u2013130.","journal-title":"Annals of the New York Academy of Sciences"},{"key":"16_CR77","doi-asserted-by":"publisher","first-page":"20150428","DOI":"10.1098\/rstb.2015.0428","volume":"371","author":"A Verkhratsky","year":"2016","unstructured":"Verkhratsky, A., & Nedergaard, M. (2016). The homeostatic astroglia emerges from evolutionary specialization of neural cells. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 371, 20150428.","journal-title":"Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences"},{"key":"16_CR78","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2023.106054","volume":"179","author":"A Verkhratsky","year":"2023","unstructured":"Verkhratsky, A., & Pivori\u016bnas, A. (2023). Astroglia support, regulate and reinforce brain barriers. Neurobiology of Disease, 179, 106054.","journal-title":"Neurobiology of Disease"},{"key":"16_CR79","volume-title":"Neuroglia: Function and pathology","author":"A Verkhratsky","year":"2023","unstructured":"Verkhratsky, A., & Butt, A. M. (2023). Neuroglia: Function and pathology. Elsevier."},{"key":"16_CR80","doi-asserted-by":"publisher","first-page":"684","DOI":"10.1111\/bpa.12085","volume":"23","author":"AS Verkman","year":"2013","unstructured":"Verkman, A. S., Phuan, P. W., Asavapanumas, N., & Tradtrantip, L. (2013). Biology of AQP4 and anti-AQP4 antibody: Therapeutic implications for NMO. Brain Pathology, 23, 684\u2013695.","journal-title":"Brain Pathology"},{"key":"16_CR81","doi-asserted-by":"publisher","first-page":"5730","DOI":"10.4049\/jimmunol.181.8.5730","volume":"181","author":"T Vincent","year":"2008","unstructured":"Vincent, T., Saikali, P., Cayrol, R., Roth, A. D., Bar-Or, A., Prat, A., & Antel, J. P. (2008). Functional consequences of neuromyelitis optica-IgG astrocyte interactions on blood-brain barrier permeability and granulocyte recruitment. Journal of Immunology, 181, 5730\u20135737.","journal-title":"Journal of Immunology"},{"key":"16_CR82","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1016\/j.nbd.2011.03.003","volume":"42","author":"SK Wasseff","year":"2011","unstructured":"Wasseff, S. K., & Scherer, S. S. (2011). Cx32 and Cx47 mediate oligodendrocyte:astrocyte and oligodendrocyte:oligodendrocyte gap junction coupling. Neurobiology of Disease, 42, 506\u2013513.","journal-title":"Neurobiology of Disease"},{"key":"16_CR83","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1212\/WNL.0000000000001729","volume":"85","author":"DM Wingerchuk","year":"2015","unstructured":"Wingerchuk, D. M., Banwell, B., Bennett, J. L., Cabre, P., Carroll, W., Chitnis, T., de Seze, J., Fujihara, K., Greenberg, B., Jacob, A., et al. (2015). International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology, 85, 177\u2013189.","journal-title":"Neurology"},{"key":"16_CR84","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1056\/NEJMra1904655","volume":"387","author":"DM Wingerchuk","year":"2022","unstructured":"Wingerchuk, D. M., Ropper, A. H., & Lucchinetti, C. F. (2022). Neuromyelitis optica spectrum disorder. New England Journal of Medicine, 387, 631\u2013639.","journal-title":"New England Journal of Medicine"},{"key":"16_CR85","doi-asserted-by":"crossref","unstructured":"Winkler, A., Wrzos, C., Haberl, M., Weil, M.-T., Gao, M., M\u00f6bius, W., Odoardi, F., Thal, D. R., Chang, M., Opdenakker, G., et al. (2021). Blood-brain barrier resealing in neuromyelitis optica occurs independently of astrocyte regeneration. Journal of Clinical Investigation, 131.","DOI":"10.1172\/JCI141694"},{"key":"16_CR86","doi-asserted-by":"publisher","first-page":"9025","DOI":"10.1073\/pnas.86.22.9025","volume":"86","author":"DR Wren","year":"1989","unstructured":"Wren, D. R., & Noble, M. (1989). Oligodendrocytes and oligodendrocyte\/type-2 astrocyte progenitor cells of adult rats are specifically susceptible to the lytic effects of complement in absence of antibody. Proceedings of the National Academy of Sciences of the United States of America, 86, 9025\u20139029.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"16_CR87","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1007\/s00401-013-1220-8","volume":"127","author":"C Wrzos","year":"2013","unstructured":"Wrzos, C., Winkler, A., Metz, I., Kayser, D. M., Thal, D. R., Wegner, C., Br\u00fcck, W., Nessler, S., Bennett, J. L., & Stadelmann, C. (2013). Early loss of oligodendrocytes in human and experimental neuromyelitis optica lesions. Acta Neuropathologica, 127, 523\u2013538.","journal-title":"Acta Neuropathologica"},{"key":"16_CR88","doi-asserted-by":"publisher","first-page":"1663","DOI":"10.1038\/s41593-023-01423-3","volume":"26","author":"Y Xiao","year":"2023","unstructured":"Xiao, Y., & Czopka, T. (2023). Myelination-independent functions of oligodendrocyte precursor cells in health and disease. Nature Neuroscience, 26, 1663\u20131669.","journal-title":"Nature Neuroscience"},{"key":"16_CR89","doi-asserted-by":"crossref","unstructured":"Yao, X., Su, T., & Verkman, A. S. (2016). Clobetasol promotes remyelination in a mouse model of neuromyelitis optica. Acta Neuropathologica Communications, 4.","DOI":"10.1186\/s40478-016-0309-4"}],"container-title":["Advances in Neurobiology","Physiology and Pathophysiology of Oligodendroglia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-031-87919-7_16","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T19:05:38Z","timestamp":1749668738000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-031-87919-7_16"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"ISBN":["9783031879180","9783031879197"],"references-count":87,"URL":"https:\/\/doi.org\/10.1007\/978-3-031-87919-7_16","relation":{},"ISSN":["2190-5215","2190-5223"],"issn-type":[{"value":"2190-5215","type":"print"},{"value":"2190-5223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"12 June 2025","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}