{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T08:00:29Z","timestamp":1780732829900,"version":"3.54.1"},"publisher-location":"Cham","reference-count":14,"publisher":"Springer Nature Switzerland","isbn-type":[{"value":"9783031898433","type":"print"},{"value":"9783031898440","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T00:00:00Z","timestamp":1752105600000},"content-version":"vor","delay-in-days":190,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Moyamoya disease (MMD) is considered to run a progressive course, but little is known about its long-term outcomes. We conducted a structured phone interview to assess outcomes in a mixed cohort of conservatively and surgically treated patients a median of 9\u00a0years and up to 27\u00a0years after a diagnosis of MMD. We found that 60% of patients had a favorable outcome (modified Rankin Scale score\u00a0&lt;3), with only 16% of adult patients working full time. We conclude that MMD considerably impacts daily life in a substantial number of those affected, with only a minority able to provide for themselves.<\/jats:p>","DOI":"10.1007\/978-3-031-89844-0_11","type":"book-chapter","created":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T09:38:08Z","timestamp":1752140288000},"page":"93-97","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Long-Term Outcome of Moyamoya Disease"],"prefix":"10.1007","author":[{"given":"Peter","family":"Birkeland","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinosha","family":"Tharmabalan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Lauritsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Troels","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Truelsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sverre","family":"Rosenbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"von Weitzel-Mudersbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,10]]},"reference":[{"key":"11_CR1","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1056\/NEJMra0804622","volume":"360","author":"RM Scott","year":"2009","unstructured":"Scott RM, Smith ER. Moyamoya disease and moyamoya syndrome. N Engl J Med. 2009;360:1226\u201337.","journal-title":"N Engl J Med"},{"key":"11_CR2","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1001\/archneur.1969.00480090076012","volume":"20","author":"J Suzuki","year":"1969","unstructured":"Suzuki J, Takaku A. Cerebrovascular \"moyamoya\" disease. Disease showing abnormal net-like vessels in base of brain. Arch Neurol. 1969;20:288\u201399.","journal-title":"Arch Neurol"},{"key":"11_CR3","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1136\/jnnp-2011-301387","volume":"83","author":"R Kleinloog","year":"2012","unstructured":"Kleinloog R, Regli L, Rinkel GJE, Klijn CJM. Regional differences in incidence and patient characteristics of moyamoya disease: a systematic review. 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Effects of extracranial\u2013intracranial bypass for patients with hemorrhagic Moyamoya disease. Stroke. 2014;45:1415\u201321.","journal-title":"Stroke"},{"key":"11_CR9","doi-asserted-by":"publisher","first-page":"2446","DOI":"10.1111\/ene.14439","volume":"12","author":"P Birkeland","year":"2020","unstructured":"Birkeland P, Tharmabalan V, Lauritsen J, Bjarkam C, Ganesan V, von Weitzel-Mudersbach P. Moyamoya disease in a European setting: a Danish population-based study. Eur J Neurol. 2020;12:2446\u201352.","journal-title":"Eur J Neurol"},{"key":"11_CR10","doi-asserted-by":"crossref","unstructured":"Birkeland P, Hansen V, Tharmabalan V, Lauritsen J, Nielsen TH, Truelsen T, Rosenbaum S, von Weitzel-Mudersbach P. Long-term stroke risk in moyamoya disease. 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