{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T07:36:27Z","timestamp":1769844987148,"version":"3.49.0"},"publisher-location":"Cham","reference-count":5,"publisher":"Springer Nature Switzerland","isbn-type":[{"value":"9783031902512","type":"print"},{"value":"9783031902529","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"DOI":"10.1007\/978-3-031-90252-9_48","type":"book-chapter","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T20:03:34Z","timestamp":1745525014000},"page":"400-404","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Synthetic Control Removes Spurious Discoveries from\u00a0Double Dipping in\u00a0Single-Cell and\u00a0Spatial Transcriptomics Data Analyses"],"prefix":"10.1007","author":[{"given":"Dongyuan","family":"Song","sequence":"first","affiliation":[]},{"given":"Siqi","family":"Chen","sequence":"additional","affiliation":[]},{"given":"Christy","family":"Lee","sequence":"additional","affiliation":[]},{"given":"Kexin","family":"Li","sequence":"additional","affiliation":[]},{"given":"Xinzhou","family":"Ge","sequence":"additional","affiliation":[]},{"given":"Jingyi Jessica","family":"Li","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2025,4,25]]},"reference":[{"issue":"1","key":"48_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13059-021-02506-9","volume":"22","author":"X Ge","year":"2021","unstructured":"Ge, X., et al.: Clipper: p-value-free FDR control on high-throughput data from two conditions. Genome Biol. 22(1), 1\u201329 (2021)","journal-title":"Genome Biol."},{"issue":"1","key":"48_CR2","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1093\/biostatistics\/kxac047","volume":"25","author":"A Neufeld","year":"2024","unstructured":"Neufeld, A., Gao, L.L., Popp, J., Battle, A., Witten, D.: Inference after latent variable estimation for single-cell RNA sequencing data. Biostatistics 25(1), 270\u2013287 (2024)","journal-title":"Biostatistics"},{"issue":"2","key":"48_CR3","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1038\/s41587-023-01772-1","volume":"42","author":"D Song","year":"2024","unstructured":"Song, D., Wang, Q., Yan, G., Liu, T., Sun, T., Li, J.J.: scDesign3 generates realistic in silico data for multimodal single-cell and spatial omics. Nat. Biotechnol. 42(2), 247\u2013252 (2024)","journal-title":"Nat. Biotechnol."},{"issue":"4","key":"48_CR4","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.cels.2019.07.012","volume":"9","author":"JM Zhang","year":"2019","unstructured":"Zhang, J.M., Kamath, G.M., David, N.T.: Valid post-clustering differential analysis for single-cell RNA-seq. Cell Syst. 9(4), 383\u2013392 (2019)","journal-title":"Cell Syst."},{"issue":"11","key":"48_CR5","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.1038\/s41587-021-00935-2","volume":"39","author":"E Zhao","year":"2021","unstructured":"Zhao, E., et al.: Spatial transcriptomics at subspot resolution with BayesSpace. Nat. Biotechnol. 39(11), 1375\u20131384 (2021)","journal-title":"Nat. Biotechnol."}],"container-title":["Lecture Notes in Computer Science","Research in Computational Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-031-90252-9_48","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T20:03:35Z","timestamp":1745525015000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-031-90252-9_48"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"ISBN":["9783031902512","9783031902529"],"references-count":5,"URL":"https:\/\/doi.org\/10.1007\/978-3-031-90252-9_48","relation":{},"ISSN":["0302-9743","1611-3349"],"issn-type":[{"value":"0302-9743","type":"print"},{"value":"1611-3349","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"25 April 2025","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}},{"value":"RECOMB","order":1,"name":"conference_acronym","label":"Conference Acronym","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"International Conference on Research in Computational Molecular Biology","order":2,"name":"conference_name","label":"Conference Name","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Seoul","order":3,"name":"conference_city","label":"Conference City","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Korea (Republic of)","order":4,"name":"conference_country","label":"Conference Country","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"2025","order":5,"name":"conference_year","label":"Conference Year","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"26 April 2025","order":7,"name":"conference_start_date","label":"Conference Start Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"29 April 2025","order":8,"name":"conference_end_date","label":"Conference End Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"29","order":9,"name":"conference_number","label":"Conference Number","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"recomb2025","order":10,"name":"conference_id","label":"Conference ID","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"https:\/\/recomb.org\/recomb2025\/index.html","order":11,"name":"conference_url","label":"Conference URL","group":{"name":"ConferenceInfo","label":"Conference Information"}}]}}