{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:06:28Z","timestamp":1790697988096,"version":"4.1.0"},"publisher-location":"Cham","reference-count":127,"publisher":"Springer Nature Switzerland","isbn-type":[{"value":"9783031963636","type":"print"},{"value":"9783031963643","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025]]},"DOI":"10.1007\/978-3-031-96364-3_4","type":"book-chapter","created":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T08:06:12Z","timestamp":1759737972000},"page":"95-119","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Regulation of Dopamine Transporter Surface Expression"],"prefix":"10.1007","author":[{"given":"Christina","family":"Besada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole Valente","family":"Mortensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,10,7]]},"reference":[{"key":"4_CR1","doi-asserted-by":"publisher","first-page":"12 16 1\u201312 16 1","DOI":"10.1002\/cpph.32","volume":"79","author":"S Aggarwal","year":"2017","unstructured":"Aggarwal S, Mortensen OV (2017) Overview of monoamine transporters. Curr Protoc Pharmacol 79:12 16 1\u201312 16 17. https:\/\/doi.org\/10.1002\/cpph.32. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29261228","journal-title":"Curr Protoc Pharmacol"},{"key":"4_CR2","doi-asserted-by":"publisher","first-page":"100029","DOI":"10.1016\/j.addicn.2022.100029","volume":"3","author":"IP Alonso","year":"2022","unstructured":"Alonso IP, O\u2019Connor BM, Bryant KG, Mandalaywala RK, Espana RA (2022) Incubation of cocaine craving coincides with changes in dopamine terminal neurotransmission. Addict Neurosci 3:100029. https:\/\/doi.org\/10.1016\/j.addicn.2022.100029. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/36081573","journal-title":"Addict Neurosci"},{"issue":"5","key":"4_CR3","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1038\/mp.2017.16","volume":"22","author":"AH Ashok","year":"2017","unstructured":"Ashok AH, Marques TR, Jauhar S, Nour MM, Goodwin GM, Young AH, Howes OD (2017) The dopamine hypothesis of bipolar affective disorder: the state of the art and implications for treatment. Mol Psychiatry 22(5):666\u2013679. https:\/\/doi.org\/10.1038\/mp.2017.16. https:\/\/www.nature.com\/articles\/mp201716.pdf","journal-title":"Mol Psychiatry"},{"issue":"1","key":"4_CR4","doi-asserted-by":"publisher","first-page":"ENEURO.0491","DOI":"10.1523\/ENEURO.0491-23.2023","volume":"11","author":"T Bagalkot","year":"2024","unstructured":"Bagalkot T, Sorkin A (2024) Amphetamine induces sex-dependent loss of the Striatal Dopamine transporter in sensitized mice. eNeuro 11(1):ENEURO.0491. https:\/\/doi.org\/10.1523\/ENEURO.0491-23.2023. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/38164591","journal-title":"eNeuro"},{"issue":"5","key":"4_CR5","doi-asserted-by":"publisher","first-page":"e0727232023","DOI":"10.1523\/JNEUROSCI.0727-23.2023","volume":"44","author":"DL Bernstein","year":"2024","unstructured":"Bernstein DL, Lewandowski SI, Besada C, Place D, Espana RA, Mortensen OV (2024) Inactivation of ERK1\/2 signaling in dopaminergic neurons by Map Kinase phosphatase MKP3 regulates Dopamine signaling and motivation for cocaine. J Neurosci 44(5):e0727232023. https:\/\/doi.org\/10.1523\/JNEUROSCI.0727-23.2023. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/38296649","journal-title":"J Neurosci"},{"issue":"5","key":"4_CR6","doi-asserted-by":"publisher","first-page":"1222","DOI":"10.1124\/mol.106.027763","volume":"71","author":"EA Bolan","year":"2007","unstructured":"Bolan EA, Kivell B, Jaligam V, Oz M, Jayanthi LD, Han Y, Sen N, Urizar E, Gomes I, Devi LA, Ramamoorthy S, Javitch JA, Zapata A, Shippenberg TS (2007) D2 receptors regulate dopamine transporter function via an extracellular signal-regulated kinases 1 and 2-dependent and phosphoinositide 3 kinase-independent mechanism. Mol Pharmacol 71(5):1222\u20131232. https:\/\/doi.org\/10.1124\/mol.106.027763. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17267664","journal-title":"Mol Pharmacol"},{"issue":"2","key":"4_CR7","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/s0092-8674(03)01079-1","volume":"116","author":"JS Bonifacino","year":"2004","unstructured":"Bonifacino JS, Glick BS (2004) The mechanisms of vesicle budding and fusion. Cell 116(2):153\u2013166. https:\/\/doi.org\/10.1016\/s0092-8674(03)01079-1. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/14744428","journal-title":"Cell"},{"issue":"3","key":"4_CR8","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1016\/j.neuropharm.2007.11.007","volume":"54","author":"E Boudanova","year":"2008","unstructured":"Boudanova E, Navaroli DM, Melikian HE (2008a) Amphetamine-induced decreases in dopamine transporter surface expression are protein kinase C-independent. Neuropharmacology 54(3):605\u2013612. https:\/\/doi.org\/10.1016\/j.neuropharm.2007.11.007. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18164041","journal-title":"Neuropharmacology"},{"issue":"2","key":"4_CR9","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.mcn.2008.06.011","volume":"39","author":"E Boudanova","year":"2008","unstructured":"Boudanova E, Navaroli DM, Stevens Z, Melikian HE (2008b) Dopamine transporter endocytic determinants: carboxy terminal residues critical for basal and PKC-stimulated internalization. Mol Cell Neurosci 39(2):211\u2013217. https:\/\/doi.org\/10.1016\/j.mcn.2008.06.011","journal-title":"Mol Cell Neurosci"},{"issue":"12","key":"4_CR10","doi-asserted-by":"publisher","first-page":"2385","DOI":"10.1038\/npp.2013.136","volume":"38","author":"ES Calipari","year":"2013","unstructured":"Calipari ES, Ferris MJ, Zimmer BA, Roberts DC, Jones SR (2013) Temporal pattern of cocaine intake determines tolerance vs sensitization of cocaine effects at the dopamine transporter. Neuropsychopharmacology 38(12):2385\u20132392. https:\/\/doi.org\/10.1038\/npp.2013.136. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23719505","journal-title":"Neuropsychopharmacology"},{"issue":"16","key":"4_CR11","doi-asserted-by":"publisher","first-page":"7045","DOI":"10.1523\/JNEUROSCI.22-16-07045.2002","volume":"22","author":"AM Carneiro","year":"2002","unstructured":"Carneiro AM, Ingram SL, Beaulieu JM, Sweeney A, Amara SG, Thomas SM, Caron MG, Torres GE (2002) The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter. J Neurosci 22(16):7045\u20137054. https:\/\/doi.org\/10.1523\/JNEUROSCI.22-16-07045.2002. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12177201","journal-title":"J Neurosci"},{"key":"4_CR12","doi-asserted-by":"publisher","first-page":"35","DOI":"10.3389\/fncel.2019.00035","volume":"13","author":"E Cartier","year":"2019","unstructured":"Cartier E, Garcia-Olivares J, Janezic E, Viana J, Moore M, Lin ML, Caplan JL, Torres G, Kim YH (2019) The SUMO-Conjugase Ubc9 prevents the degradation of the Dopamine transporter, enhancing its cell surface level and Dopamine uptake. Front Cell Neurosci 13:35. https:\/\/doi.org\/10.3389\/fncel.2019.00035","journal-title":"Front Cell Neurosci"},{"issue":"1","key":"4_CR13","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1111\/j.1471-4159.1993.tb03565.x","volume":"61","author":"WA Cass","year":"1993","unstructured":"Cass WA, Gerhardt GA, Gillespie K, Curella P, Mayfield RD, Zahniser NR (1993) Reduced clearance of exogenous dopamine in rat nucleus accumbens, but not in dorsal striatum, following cocaine challenge in rats withdrawn from repeated cocaine administration. J Neurochem 61(1):273\u2013283. https:\/\/doi.org\/10.1111\/j.1471-4159.1993.tb03565.x. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8515274","journal-title":"J Neurochem"},{"key":"4_CR14","doi-asserted-by":"publisher","first-page":"349, 451","DOI":"10.1038\/sj.mp.4002132","volume":"13(4)","author":"X Cen","year":"2008","unstructured":"Cen X, Nitta A, Ibi D, Zhao Y, Niwa M, Taguchi K, Hamada M, Ito Y, Ito Y, Wang L, Nabeshima T (2008) Identification of Piccolo as a regulator of behavioral plasticity and dopamine transporter internalization. Mol Psychiatry 13(4):349, 451\u2013349, 463. https:\/\/doi.org\/10.1038\/sj.mp.4002132. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18195717","journal-title":"Mol Psychiatry"},{"issue":"49","key":"4_CR15","doi-asserted-by":"publisher","first-page":"40442","DOI":"10.1074\/jbc.M501969200","volume":"280","author":"MA Cervinski","year":"2005","unstructured":"Cervinski MA, Foster JD, Vaughan RA (2005) Psychoactive substrates stimulate dopamine transporter phosphorylation and down-regulation by cocaine-sensitive and protein kinase C-dependent mechanisms. J Biol Chem 280(49):40442\u201340449. https:\/\/doi.org\/10.1074\/jbc.M501969200","journal-title":"J Biol Chem"},{"issue":"2","key":"4_CR16","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1016\/j.neuroscience.2010.07.025","volume":"170","author":"MA Cervinski","year":"2010","unstructured":"Cervinski MA, Foster JD, Vaughan RA (2010) Syntaxin 1A regulates dopamine transporter activity, phosphorylation and surface expression. Neuroscience 170(2):408\u2013416. https:\/\/doi.org\/10.1016\/j.neuroscience.2010.07.025. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20643191","journal-title":"Neuroscience"},{"issue":"46","key":"4_CR17","doi-asserted-by":"publisher","first-page":"19066","DOI":"10.1074\/jbc.M117.787002","volume":"292","author":"S Challasivakanaka","year":"2017","unstructured":"Challasivakanaka S, Zhen J, Smith ME, Reith MEA, Foster JD, Vaughan RA (2017) Dopamine transporter phosphorylation site threonine 53 is stimulated by amphetamines and regulates dopamine transport, efflux, and cocaine analog binding. J Biol Chem 292(46):19066\u201319075. https:\/\/doi.org\/10.1074\/jbc.M117.787002. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28939767","journal-title":"J Biol Chem"},{"issue":"4","key":"4_CR18","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1016\/s0306-4522(02)00099-4","volume":"112","author":"VI Chefer","year":"2002","unstructured":"Chefer VI, Shippenberg TS (2002) Changes in basal and cocaine-evoked extracellular dopamine uptake and release in the rat nucleus accumbens during early abstinence from cocaine: quantitative determination under transient conditions. Neuroscience 112(4):907\u2013919. https:\/\/doi.org\/10.1016\/s0306-4522(02)00099-4. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12088750","journal-title":"Neuroscience"},{"issue":"5","key":"4_CR19","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1111\/jnc.12229","volume":"125","author":"R Chen","year":"2013","unstructured":"Chen R, Daining CP, Sun H, Fraser R, Stokes SL, Leitges M, Gnegy ME (2013) Protein kinase Cbeta is a modulator of the dopamine D2 autoreceptor-activated trafficking of the dopamine transporter. J Neurochem 125(5):663\u2013672. https:\/\/doi.org\/10.1111\/jnc.12229. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23458603","journal-title":"J Neurochem"},{"issue":"3","key":"4_CR20","doi-asserted-by":"publisher","first-page":"912","DOI":"10.1124\/jpet.108.147959","volume":"328","author":"R Chen","year":"2009","unstructured":"Chen R, Furman CA, Zhang M, Kim MN, Gereau RWT, Leitges M, Gnegy ME (2009) Protein kinase Cbeta is a critical regulator of dopamine transporter trafficking and regulates the behavioral response to amphetamine in mice. J Pharmacol Exp Ther 328(3):912\u2013920. https:\/\/doi.org\/10.1124\/jpet.108.147959","journal-title":"J Pharmacol Exp Ther"},{"issue":"1","key":"4_CR21","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/s0014-2999(99)00828-6","volume":"389","author":"RM Cowell","year":"2000","unstructured":"Cowell RM, Kantor L, Hewlett GH, Frey KA, Gnegy ME (2000) Dopamine transporter antagonists block phorbol ester-induced dopamine release and dopamine transporter phosphorylation in striatal synaptosomes. Eur J Pharmacol 389(1):59\u201365. https:\/\/doi.org\/10.1016\/s0014-2999(99)00828-6","journal-title":"Eur J Pharmacol"},{"issue":"4","key":"4_CR22","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1038\/nn.2781","volume":"14","author":"ML Cremona","year":"2011","unstructured":"Cremona ML, Matthies HJ, Pau K, Bowton E, Speed N, Lute BJ, Anderson M, Sen N, Robertson SD, Vaughan RA, Rothman JE, Galli A, Javitch JA, Yamamoto A (2011) Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT. Nat Neurosci 14(4):469\u2013477. https:\/\/doi.org\/10.1038\/nn.2781. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21399631","journal-title":"Nat Neurosci"},{"key":"4_CR23","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.pharmthera.2018.06.013","volume":"192","author":"LC Czuba","year":"2018","unstructured":"Czuba LC, Hillgren KM, Swaan PW (2018) Post-translational modifications of transporters. Pharmacol Ther 192:88\u201399. https:\/\/doi.org\/10.1016\/j.pharmthera.2018.06.013","journal-title":"Pharmacol Ther"},{"issue":"50","key":"4_CR24","doi-asserted-by":"publisher","first-page":"35794","DOI":"10.1074\/jbc.274.50.35794","volume":"274","author":"GM Daniels","year":"1999","unstructured":"Daniels GM, Amara SG (1999) Regulated trafficking of the human dopamine transporter. Clathrin-mediated internalization and lysosomal degradation in response to phorbol esters. J Biol Chem 274(50):35794\u201335801. https:\/\/doi.org\/10.1074\/jbc.274.50.35794","journal-title":"J Biol Chem"},{"issue":"5","key":"4_CR25","doi-asserted-by":"publisher","first-page":"1545","DOI":"10.1006\/bbrc.2002.6384","volume":"290","author":"LC Daws","year":"2002","unstructured":"Daws LC, Callaghan PD, Mor\u00f3n JA, Kahlig KM, Shippenberg TS, Javitch JA, Galli A (2002) Cocaine increases dopamine uptake and cell surface expression of dopamine transporters. Biochem Biophys Res Commun 290(5):1545\u20131550. https:\/\/doi.org\/10.1006\/bbrc.2002.6384","journal-title":"Biochem Biophys Res Commun"},{"issue":"35","key":"4_CR26","doi-asserted-by":"publisher","first-page":"27289","DOI":"10.1074\/jbc.M110.131003","volume":"285","author":"J Eriksen","year":"2010","unstructured":"Eriksen J, Bj\u00f8rn-Yoshimoto WE, J\u00f8rgensen TN, Newman AH, Gether U (2010) Postendocytic sorting of constitutively internalized dopamine transporter in cell lines and dopaminergic neurons. J Biol Chem 285(35):27289\u201327301. https:\/\/doi.org\/10.1074\/jbc.M110.131003","journal-title":"J Biol Chem"},{"issue":"21","key":"4_CR27","doi-asserted-by":"publisher","first-page":"6794","DOI":"10.1523\/jneurosci.4177-08.2009","volume":"29","author":"J Eriksen","year":"2009","unstructured":"Eriksen J, Rasmussen SG, Rasmussen TN, Vaegter CB, Cha JH, Zou MF, Newman AH, Gether U (2009) Visualization of dopamine transporter trafficking in live neurons by use of fluorescent cocaine analogs. J Neurosci 29(21):6794\u20136808. https:\/\/doi.org\/10.1523\/jneurosci.4177-08.2009","journal-title":"J Neurosci"},{"issue":"6","key":"4_CR28","doi-asserted-by":"publisher","first-page":"1335","DOI":"10.1007\/s11064-020-03001-6","volume":"45","author":"RR Fagan","year":"2020","unstructured":"Fagan RR, Kearney PJ, Melikian HE (2020a) In situ regulated Dopamine transporter trafficking: there\u2019s no place like home. Neurochem Res 45(6):1335\u20131343. https:\/\/doi.org\/10.1007\/s11064-020-03001-6","journal-title":"Neurochem Res"},{"issue":"16","key":"4_CR29","doi-asserted-by":"publisher","first-page":"5229","DOI":"10.1074\/jbc.RA120.012628","volume":"295","author":"RR Fagan","year":"2020","unstructured":"Fagan RR, Kearney PJ, Sweeney CG, Luethi D, Schoot Uiterkamp FE, Schicker K, Alejandro BS, O\u2019Connor LC, Sitte HH, Melikian HE (2020b) Dopamine transporter trafficking and Rit2 GTPase: mechanism of action and in vivo impact. J Biol Chem 295(16):5229\u20135244. https:\/\/doi.org\/10.1074\/jbc.RA120.012628. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32132171","journal-title":"J Biol Chem"},{"issue":"7","key":"4_CR30","doi-asserted-by":"publisher","first-page":"1708","DOI":"10.1038\/npp.2012.17","volume":"37","author":"MJ Ferris","year":"2012","unstructured":"Ferris MJ, Calipari ES, Mateo Y, Melchior JR, Roberts DC, Jones SR (2012) Cocaine self-administration produces pharmacodynamic tolerance: differential effects on the potency of dopamine transporter blockers, releasers, and methylphenidate. Neuropsychopharmacology 37(7):1708\u20131716. https:\/\/doi.org\/10.1038\/npp.2012.17. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22395730","journal-title":"Neuropsychopharmacology"},{"issue":"2","key":"4_CR31","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.bbrc.2011.01.069","volume":"406","author":"AW Fjorback","year":"2011","unstructured":"Fjorback AW, Muller HK, Haase J, Raarup MK, Wiborg O (2011) Modulation of the dopamine transporter by interaction with Secretory Carrier Membrane Protein 2. Biochem Biophys Res Commun 406(2):165\u2013170. https:\/\/doi.org\/10.1016\/j.bbrc.2011.01.069. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21295544","journal-title":"Biochem Biophys Res Commun"},{"issue":"5","key":"4_CR32","doi-asserted-by":"publisher","first-page":"1683","DOI":"10.1111\/j.1471-4159.2008.05262.x","volume":"105","author":"JD Foster","year":"2008","unstructured":"Foster JD, Adkins SD, Lever JR, Vaughan RA (2008) Phorbol ester induced trafficking-independent regulation and enhanced phosphorylation of the dopamine transporter associated with membrane rafts and cholesterol. J Neurochem 105(5):1683\u20131699. https:\/\/doi.org\/10.1111\/j.1471-4159.2008.05262.x. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18248623","journal-title":"J Neurochem"},{"issue":"28","key":"4_CR33","doi-asserted-by":"publisher","first-page":"25178","DOI":"10.1074\/jbc.M200294200","volume":"277","author":"JD Foster","year":"2002","unstructured":"Foster JD, Pananusorn B, Vaughan RA (2002) Dopamine transporters are phosphorylated on N-terminal serines in rat striatum. J Biol Chem 277(28):25178\u201325186. https:\/\/doi.org\/10.1074\/jbc.M200294200","journal-title":"J Biol Chem"},{"issue":"7","key":"4_CR34","doi-asserted-by":"publisher","first-page":"5175","DOI":"10.1074\/jbc.M110.187872","volume":"286","author":"JD Foster","year":"2011","unstructured":"Foster JD, Vaughan RA (2011) Palmitoylation controls dopamine transporter kinetics, degradation, and protein kinase C-dependent regulation. J Biol Chem 286(7):5175\u20135186. https:\/\/doi.org\/10.1074\/jbc.M110.187872","journal-title":"J Biol Chem"},{"issue":"35","key":"4_CR35","doi-asserted-by":"publisher","first-page":"29702","DOI":"10.1074\/jbc.M112.367706","volume":"287","author":"JD Foster","year":"2012","unstructured":"Foster JD, Yang JW, Moritz AE, Challasivakanaka S, Smith MA, Holy M, Wilebski K, Sitte HH, Vaughan RA (2012) Dopamine transporter phosphorylation site threonine 53 regulates substrate reuptake and amphetamine-stimulated efflux. J Biol Chem 287(35):29702\u201329712. https:\/\/doi.org\/10.1074\/jbc.M112.367706. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22722938","journal-title":"J Biol Chem"},{"issue":"10","key":"4_CR36","doi-asserted-by":"publisher","first-page":"3328","DOI":"10.1523\/JNEUROSCI.5386-08.2009","volume":"29","author":"CA Furman","year":"2009","unstructured":"Furman CA, Chen R, Guptaroy B, Zhang M, Holz RW, Gnegy M (2009a) Dopamine and amphetamine rapidly increase dopamine transporter trafficking to the surface: live-cell imaging using total internal reflection fluorescence microscopy. J Neurosci 29(10):3328\u20133336. https:\/\/doi.org\/10.1523\/JNEUROSCI.5386-08.2009. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19279270","journal-title":"J Neurosci"},{"issue":"1","key":"4_CR37","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.neulet.2009.07.049","volume":"463","author":"CA Furman","year":"2009","unstructured":"Furman CA, Lo CB, Stokes S, Esteban JA, Gnegy ME (2009b) Rab 11 regulates constitutive dopamine transporter trafficking and function in N2A neuroblastoma cells. Neurosci Lett 463(1):78\u201381. https:\/\/doi.org\/10.1016\/j.neulet.2009.07.049. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19631257","journal-title":"Neurosci Lett"},{"issue":"45","key":"4_CR38","doi-asserted-by":"publisher","first-page":"17836","DOI":"10.1523\/JNEUROSCI.3284-13.2013","volume":"33","author":"LR Gabriel","year":"2013","unstructured":"Gabriel LR, Wu S, Kearney P, Bellve KD, Standley C, Fogarty KE, Melikian HE (2013) Dopamine transporter endocytic trafficking in striatal dopaminergic neurons: differential dependence on dynamin and the actin cytoskeleton. J Neurosci 33(45):17836\u201317846. https:\/\/doi.org\/10.1523\/JNEUROSCI.3284-13.2013. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24198373","journal-title":"J Neurosci"},{"issue":"1","key":"4_CR39","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1124\/mol.104.009092","volume":"68","author":"BG Garcia","year":"2005","unstructured":"Garcia BG, Wei Y, Moron JA, Lin RZ, Javitch JA, Galli A (2005) Akt is essential for insulin modulation of amphetamine-induced human dopamine transporter cell-surface redistribution. Mol Pharmacol 68(1):102\u2013109. https:\/\/doi.org\/10.1124\/mol.104.009092. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15795321","journal-title":"Mol Pharmacol"},{"issue":"23","key":"4_CR40","doi-asserted-by":"publisher","first-page":"5302","DOI":"10.1523\/JNEUROSCI.0055-18.2018","volume":"38","author":"R Gowrishankar","year":"2018","unstructured":"Gowrishankar R, Gresch PJ, Davis GL, Katamish RM, Riele JR, Stewart AM, Vaughan RA, Hahn MK, Blakely RD (2018) Region-specific regulation of presynaptic Dopamine homeostasis by D(2) autoreceptors shapes the in vivo impact of the neuropsychiatric disease-associated DAT variant Val559. J Neurosci 38(23):5302\u20135312. https:\/\/doi.org\/10.1523\/JNEUROSCI.0055-18.2018. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29739866","journal-title":"J Neurosci"},{"issue":"7","key":"4_CR41","doi-asserted-by":"publisher","first-page":"4990","DOI":"10.1074\/jbc.M205058200","volume":"278","author":"C Granas","year":"2003","unstructured":"Granas C, Ferrer J, Loland CJ, Javitch JA, Gether U (2003) N-terminal truncation of the dopamine transporter abolishes phorbol ester- and substance P receptor-stimulated phosphorylation without impairing transporter internalization. J Biol Chem 278(7):4990\u20135000.https:\/\/doi.org\/10.1074\/jbc.M205058200","journal-title":"J Biol Chem"},{"issue":"8","key":"4_CR42","doi-asserted-by":"publisher","first-page":"2664","DOI":"10.1523\/JNEUROSCI.09-08-02664.1989","volume":"9","author":"DE Grigoriadis","year":"1989","unstructured":"Grigoriadis DE, Wilson AA, Lew R, Sharkey JS, Kuhar MJ (1989) Dopamine transport sites selectively labeled by a novel photoaffinity probe: 125I-DEEP. J Neurosci 9(8):2664\u20132670. https:\/\/doi.org\/10.1523\/JNEUROSCI.09-08-02664.1989. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/2769361","journal-title":"J Neurosci"},{"issue":"2","key":"4_CR43","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1046\/j.1471-4159.2002.01133.x","volume":"83","author":"JM Gulley","year":"2002","unstructured":"Gulley JM, Doolen S, Zahniser NR (2002) Brief, repeated exposure to substrates down-regulates dopamine transporter function in Xenopus oocytes in vitro and rat dorsal striatum in vivo. J Neurochem 83(2):400\u2013411. https:\/\/doi.org\/10.1046\/j.1471-4159.2002.01133.x","journal-title":"J Neurochem"},{"issue":"18","key":"4_CR44","doi-asserted-by":"publisher","first-page":"10055","DOI":"10.1073\/pnas.181344298","volume":"98","author":"H Hastrup","year":"2001","unstructured":"Hastrup H, Karlin A, Javitch JA (2001) Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment. Proc Natl Acad Sci USA 98(18):10055\u201310060. https:\/\/doi.org\/10.1073\/pnas.181344298. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11526230","journal-title":"Proc Natl Acad Sci USA"},{"issue":"19","key":"4_CR45","doi-asserted-by":"publisher","first-page":"7250","DOI":"10.1074\/jbc.RA118.001753","volume":"293","author":"F Herborg","year":"2018","unstructured":"Herborg F, Andreassen TF, Berlin F, Loland CJ, Gether U (2018) Neuropsychiatric disease-associated genetic variants of the dopamine transporter display heterogeneous molecular phenotypes. J Biol Chem 293(19):7250\u20137262. https:\/\/doi.org\/10.1074\/jbc.RA118.001753. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29559554","journal-title":"J Biol Chem"},{"issue":"2","key":"4_CR46","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1002\/(SICI)1096-9861(19971117)388:2<211::AID-CNE3>3.0.CO;2-4","volume":"388","author":"SM Hersch","year":"1997","unstructured":"Hersch SM, Yi H, Heilman CJ, Edwards RH, Levey AI (1997) Subcellular localization and molecular topology of the dopamine transporter in the striatum and substantia nigra. J Comp Neurol 388(2):211\u2013227. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9368838","journal-title":"J Comp Neurol"},{"issue":"7","key":"4_CR47","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1038\/nn1478","volume":"8","author":"KL Holton","year":"2005","unstructured":"Holton KL, Loder MK, Melikian HE (2005) Nonclassical, distinct endocytic signals dictate constitutive and PKC-regulated neurotransmitter transporter internalization. Nat Neurosci 8(7):881\u2013888. https:\/\/doi.org\/10.1038\/nn1478","journal-title":"Nat Neurosci"},{"issue":"42","key":"4_CR48","doi-asserted-by":"publisher","first-page":"32616","DOI":"10.1074\/jbc.M110.150565","volume":"285","author":"WC Hong","year":"2010","unstructured":"Hong WC, Amara SG (2010) Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding. J Biol Chem 285(42):32616\u201332626. https:\/\/doi.org\/10.1074\/jbc.M110.150565. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20688912","journal-title":"J Biol Chem"},{"issue":"8","key":"4_CR49","doi-asserted-by":"publisher","first-page":"2995","DOI":"10.1096\/fj.12-218727","volume":"27","author":"WC Hong","year":"2013","unstructured":"Hong WC, Amara SG (2013) Differential targeting of the dopamine transporter to recycling or degradative pathways during amphetamine- or PKC-regulated endocytosis in dopamine neurons. FASEB J 27(8):2995\u20133007. https:\/\/doi.org\/10.1096\/fj.12-218727. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23612789","journal-title":"FASEB J"},{"issue":"5","key":"4_CR50","doi-asserted-by":"publisher","first-page":"1258","DOI":"10.1111\/j.1471-4159.2007.04522.x","volume":"101","author":"BR Hoover","year":"2007","unstructured":"Hoover BR, Everett CV, Sorkin A, Zahniser NR (2007) Rapid regulation of dopamine transporters by tyrosine kinases in rat neuronal preparations. J Neurochem 101(5):1258\u20131271. https:\/\/doi.org\/10.1111\/j.1471-4159.2007.04522.x. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17419806","journal-title":"J Neurochem"},{"issue":"1","key":"4_CR51","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1152\/physrev.00059.2009","volume":"91","author":"AH Hutagalung","year":"2011","unstructured":"Hutagalung AH, Novick PJ (2011) Role of Rab GTPases in membrane traffic and cell physiology. Physiol Rev 91(1):119\u2013149. https:\/\/doi.org\/10.1152\/physrev.00059.2009","journal-title":"Physiol Rev"},{"issue":"1\u20132","key":"4_CR52","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1016\/0006-8993(90)90797-f","volume":"531","author":"S Izenwasser","year":"1990","unstructured":"Izenwasser S, Cox BM (1990) Daily cocaine treatment produces a persistent reduction of [3H]dopamine uptake in vitro in rat nucleus accumbens but not in striatum. Brain Res 531(1\u20132):338\u2013341. https:\/\/doi.org\/10.1016\/0006-8993(90)90797-f. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/2289133","journal-title":"Brain Res"},{"issue":"12","key":"4_CR53","doi-asserted-by":"publisher","first-page":"9801","DOI":"10.1007\/s11033-020-05993-4","volume":"47","author":"JL Jeger","year":"2020","unstructured":"Jeger JL (2020) Endosomes, lysosomes, and the role of endosomal and lysosomal biogenesis in cancer development. Mol Biol Rep 47(12):9801\u20139810. https:\/\/doi.org\/10.1007\/s11033-020-05993-4","journal-title":"Mol Biol Rep"},{"issue":"52","key":"4_CR54","doi-asserted-by":"publisher","first-page":"54380","DOI":"10.1074\/jbc.M409282200","volume":"279","author":"H Jiang","year":"2004","unstructured":"Jiang H, Jiang Q, Feng J (2004) Parkin increases dopamine uptake by enhancing the cell surface expression of dopamine transporter. J Biol Chem 279(52):54380\u201354386. https:\/\/doi.org\/10.1074\/jbc.M409282200. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15492001","journal-title":"J Biol Chem"},{"issue":"6","key":"4_CR55","doi-asserted-by":"publisher","first-page":"750","DOI":"10.1016\/j.neuropharm.2005.08.018","volume":"49","author":"LA Johnson","year":"2005","unstructured":"Johnson LA, Furman CA, Zhang M, Guptaroy B, Gnegy ME (2005) Rapid delivery of the dopamine transporter to the plasmalemmal membrane upon amphetamine stimulation. Neuropharmacology 49(6):750\u2013758. https:\/\/doi.org\/10.1016\/j.neuropharm.2005.08.018","journal-title":"Neuropharmacology"},{"issue":"2","key":"4_CR56","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2023.102900","volume":"299","author":"PJ Kearney","year":"2023","unstructured":"Kearney PJ, Bolden NC, Kahuno E, Conklin TL, Martin GE, Lubec G, Melikian HE (2023) Presynaptic Gq-coupled receptors drive biphasic dopamine transporter trafficking that modulates dopamine clearance and motor function. J Biol Chem 299(2):102900. https:\/\/doi.org\/10.1016\/j.jbc.2023.102900. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/36640864","journal-title":"J Biol Chem"},{"issue":"3","key":"4_CR57","doi-asserted-by":"publisher","first-page":"E78","DOI":"10.1371\/journal.pbio.0020078","volume":"2","author":"H Khoshbouei","year":"2004","unstructured":"Khoshbouei H, Sen N, Guptaroy B, Johnson L, Lund D, Gnegy ME, Galli A, Javitch JA (2004) N-terminal phosphorylation of the dopamine transporter is required for amphetamine-induced efflux. PLoS Biol 2(3):E78. https:\/\/doi.org\/10.1371\/journal.pbio.0020078","journal-title":"PLoS Biol"},{"key":"4_CR58","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.neuropharm.2014.07.016","volume":"86","author":"B Kivell","year":"2014","unstructured":"Kivell B, Uzelac Z, Sundaramurthy S, Rajamanickam J, Ewald A, Chefer V, Jaligam V, Bolan E, Simonson B, Annamalai B, Mannangatti P, Prisinzano TE, Gomes I, Devi LA, Jayanthi LD, Sitte HH, Ramamoorthy S, Shippenberg TS (2014) Salvinorin A regulates dopamine transporter function via a kappa opioid receptor and ERK1\/2-dependent mechanism. Neuropharmacology 86:228\u2013240. https:\/\/doi.org\/10.1016\/j.neuropharm.2014.07.016. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25107591","journal-title":"Neuropharmacology"},{"issue":"2\u20133","key":"4_CR59","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/s0014-2999(98)00741-9","volume":"361","author":"JM Kokoshka","year":"1998","unstructured":"Kokoshka JM, Vaughan RA, Hanson GR, Fleckenstein AE (1998) Nature of methamphetamine-induced rapid and reversible changes in dopamine transporters. Eur J Pharmacol 361(2\u20133):269\u2013275. https:\/\/doi.org\/10.1016\/s0014-2999(98)00741-9","journal-title":"Eur J Pharmacol"},{"key":"4_CR60","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.neuropharm.2008.07.043","volume":"56(Suppl 1)","author":"GF Koob","year":"2009","unstructured":"Koob GF (2009) Neurobiological substrates for the dark side of compulsivity in addiction. Neuropharmacology 56(Suppl 1):18\u201331. https:\/\/doi.org\/10.1016\/j.neuropharm.2008.07.043. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18725236","journal-title":"Neuropharmacology"},{"issue":"3","key":"4_CR61","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1124\/pr.108.000869","volume":"63","author":"AS Kristensen","year":"2011","unstructured":"Kristensen AS, Andersen J, Jorgensen TN, Sorensen L, Eriksen J, Loland CJ, Stromgaard K, Gether U (2011) SLC6 neurotransmitter transporters: structure, function, and regulation. Pharmacol Rev 63(3):585\u2013640. https:\/\/doi.org\/10.1124\/pr.108.000869. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21752877","journal-title":"Pharmacol Rev"},{"issue":"6","key":"4_CR62","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1096\/fj.00-0334com","volume":"15","author":"FJ Lee","year":"2001","unstructured":"Lee FJ, Liu F, Pristupa ZB, Niznik HB (2001) Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis. FASEB J 15(6):916\u2013926. https:\/\/doi.org\/10.1096\/fj.00-0334com. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11292651","journal-title":"FASEB J"},{"issue":"8","key":"4_CR63","doi-asserted-by":"publisher","first-page":"2127","DOI":"10.1038\/sj.emboj.7601656","volume":"26","author":"FJ Lee","year":"2007","unstructured":"Lee FJ, Pei L, Moszczynska A, Vukusic B, Fletcher PJ, Liu F (2007) Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptor. EMBO J 26(8):2127\u20132136. https:\/\/doi.org\/10.1038\/sj.emboj.7601656. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17380124","journal-title":"EMBO J"},{"issue":"20","key":"4_CR64","doi-asserted-by":"publisher","first-page":"21012","DOI":"10.1074\/jbc.M311972200","volume":"279","author":"LB Li","year":"2004","unstructured":"Li LB, Chen N, Ramamoorthy S, Chi L, Cui XN, Wang LC, Reith ME (2004) The role of N-glycosylation in function and surface trafficking of the human dopamine transporter. J Biol Chem 279(20):21012\u201321020. https:\/\/doi.org\/10.1074\/jbc.M311972200. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15024013","journal-title":"J Biol Chem"},{"issue":"22","key":"4_CR65","doi-asserted-by":"publisher","first-page":"20162","DOI":"10.1074\/jbc.M209584200","volume":"278","author":"Z Lin","year":"2003","unstructured":"Lin Z, Zhang PW, Zhu X, Melgari JM, Huff R, Spieldoch RL, Uhl GR (2003) Phosphatidylinositol 3-kinase, protein kinase C, and MEK1\/2 kinase regulation of dopamine transporters (DAT) require N-terminal DAT phosphoacceptor sites. J Biol Chem 278(22):20162\u201320170. https:\/\/doi.org\/10.1074\/jbc.M209584200. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12660249","journal-title":"J Biol Chem"},{"issue":"2","key":"4_CR66","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1124\/mol.61.2.436","volume":"61","author":"KY Little","year":"2002","unstructured":"Little KY, Elmer LW, Zhong H, Scheys JO, Zhang L (2002) Cocaine induction of dopamine transporter trafficking to the plasma membrane. Mol Pharmacol 61(2):436\u2013445. https:\/\/doi.org\/10.1124\/mol.61.2.436. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11809869","journal-title":"Mol Pharmacol"},{"issue":"1\u20132","key":"4_CR67","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/0006-8993(93)90932-d","volume":"628","author":"KY Little","year":"1993","unstructured":"Little KY, Kirkman JA, Carroll FI, Clark TB, Duncan GE (1993) Cocaine use increases [3H]WIN 35428 binding sites in human striatum. Brain Res 628(1\u20132):17\u201325. https:\/\/doi.org\/10.1016\/0006-8993(93)90932-d. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8313144","journal-title":"Brain Res"},{"issue":"24","key":"4_CR68","doi-asserted-by":"publisher","first-page":"22168","DOI":"10.1074\/jbc.M301845200","volume":"278","author":"MK Loder","year":"2003","unstructured":"Loder MK, Melikian HE (2003) The dopamine transporter constitutively internalizes and recycles in a protein kinase C-regulated manner in stably transfected PC12 cell lines. J Biol Chem 278(24):22168\u201322174. https:\/\/doi.org\/10.1074\/jbc.M301845200","journal-title":"J Biol Chem"},{"issue":"4","key":"4_CR69","doi-asserted-by":"publisher","first-page":"622","DOI":"10.1176\/ajp.2007.164.4.622","volume":"164","author":"D Martinez","year":"2007","unstructured":"Martinez D, Narendran R, Foltin RW, Slifstein M, Hwang DR, Broft A, Huang Y, Cooper TB, Fischman MW, Kleber HD, Laruelle M (2007) Amphetamine-induced dopamine release: markedly blunted in cocaine dependence and predictive of the choice to self-administer cocaine. Am J Psychiatry 164(4):622\u2013629. https:\/\/doi.org\/10.1176\/ajp.2007.164.4.622. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17403976","journal-title":"Am J Psychiatry"},{"issue":"2","key":"4_CR70","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1046\/j.1471-4159.2002.00820.x","volume":"81","author":"DC Mash","year":"2002","unstructured":"Mash DC, Pablo J, Ouyang Q, Hearn WL, Izenwasser S (2002) Dopamine transport function is elevated in cocaine users. J Neurochem 81(2):292\u2013300. https:\/\/doi.org\/10.1046\/j.1471-4159.2002.00820.x. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12064476","journal-title":"J Neurochem"},{"issue":"8","key":"4_CR71","doi-asserted-by":"publisher","first-page":"1455","DOI":"10.1038\/sj.npp.1300687","volume":"30","author":"Y Mateo","year":"2005","unstructured":"Mateo Y, Lack CM, Morgan D, Roberts DC, Jones SR (2005) Reduced dopamine terminal function and insensitivity to cocaine following cocaine binge self-administration and deprivation. Neuropsychopharmacology 30(8):1455\u20131463. https:\/\/doi.org\/10.1038\/sj.npp.1300687. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15702135","journal-title":"Neuropsychopharmacology"},{"issue":"18","key":"4_CR72","doi-asserted-by":"publisher","first-page":"7699","DOI":"10.1523\/JNEUROSCI.19-18-07699.1999","volume":"19","author":"HE Melikian","year":"1999","unstructured":"Melikian HE, Buckley KM (1999) Membrane trafficking regulates the activity of the human dopamine transporter. J Neurosci 19(18):7699\u20137710. https:\/\/doi.org\/10.1523\/JNEUROSCI.19-18-07699.1999. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10479674","journal-title":"J Neurosci"},{"issue":"1","key":"4_CR73","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1091\/mbc.e06-08-0704","volume":"18","author":"M Miranda","year":"2007","unstructured":"Miranda M, Dionne KR, Sorkina T, Sorkin A (2007) Three ubiquitin conjugation sites in the amino terminus of the dopamine transporter mediate protein kinase C-dependent endocytosis of the transporter. Mol Biol Cell 18(1):313\u2013323. https:\/\/doi.org\/10.1091\/mbc.e06-08-0704","journal-title":"Mol Biol Cell"},{"issue":"42","key":"4_CR74","doi-asserted-by":"publisher","first-page":"35617","DOI":"10.1074\/jbc.M506618200","volume":"280","author":"M Miranda","year":"2005","unstructured":"Miranda M, Wu CC, Sorkina T, Korstjens DR, Sorkin A (2005) Enhanced ubiquitylation and accelerated degradation of the dopamine transporter mediated by protein kinase C. J Biol Chem 280(42):35617\u201335624. https:\/\/doi.org\/10.1074\/jbc.M506618200","journal-title":"J Biol Chem"},{"issue":"1","key":"4_CR75","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1074\/jbc.M112.407874","volume":"288","author":"AE Moritz","year":"2013","unstructured":"Moritz AE, Foster JD, Gorentla BK, Mazei-Robison MS, Yang JW, Sitte HH, Blakely RD, Vaughan RA (2013) Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding. J Biol Chem 288(1):20\u201332. https:\/\/doi.org\/10.1074\/jbc.M112.407874. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23161550","journal-title":"J Biol Chem"},{"issue":"48","key":"4_CR76","doi-asserted-by":"publisher","first-page":"29095","DOI":"10.1074\/jbc.M115.667055","volume":"290","author":"AE Moritz","year":"2015","unstructured":"Moritz AE, Rastedt DE, Stanislowski DJ, Shetty M, Smith MA, Vaughan RA, Foster JD (2015) Reciprocal phosphorylation and palmitoylation control Dopamine transporter kinetics. J Biol Chem 290(48):29095\u201329105. https:\/\/doi.org\/10.1074\/jbc.M115.667055","journal-title":"J Biol Chem"},{"issue":"24","key":"4_CR77","doi-asserted-by":"publisher","first-page":"8480","DOI":"10.1523\/JNEUROSCI.23-24-08480.2003","volume":"23","author":"JA Moron","year":"2003","unstructured":"Moron JA, Zakharova I, Ferrer JV, Merrill GA, Hope B, Lafer EM, Lin ZC, Wang JB, Javitch JA, Galli A, Shippenberg TS (2003) Mitogen-activated protein kinase regulates dopamine transporter surface expression and dopamine transport capacity. J Neurosci 23(24):8480\u20138488. https:\/\/doi.org\/10.1523\/JNEUROSCI.23-24-08480.2003. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/13679416","journal-title":"J Neurosci"},{"issue":"7","key":"4_CR78","doi-asserted-by":"publisher","first-page":"2818","DOI":"10.1091\/mbc.e07-09-0980","volume":"19","author":"OV Mortensen","year":"2008","unstructured":"Mortensen OV, Larsen MB, Prasad BM, Amara SG (2008) Genetic complementation screen identifies a mitogen-activated protein kinase phosphatase, MKP3, as a regulator of dopamine transporter trafficking. Mol Biol Cell 19(7):2818\u20132829. https:\/\/doi.org\/10.1091\/mbc.e07-09-0980","journal-title":"Mol Biol Cell"},{"issue":"3","key":"4_CR79","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/s12031-007-0037-0","volume":"32","author":"A Moszczynska","year":"2007","unstructured":"Moszczynska A, Saleh J, Zhang H, Vukusic B, Lee FJ, Liu F (2007) Parkin disrupts the alpha-synuclein\/dopamine transporter interaction: consequences toward dopamine-induced toxicity. J Mol Neurosci 32(3):217\u2013227. https:\/\/doi.org\/10.1007\/s12031-007-0037-0. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17873367","journal-title":"J Mol Neurosci"},{"issue":"3","key":"4_CR80","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1152\/physrev.1997.77.3.759","volume":"77","author":"S Mukherjee","year":"1997","unstructured":"Mukherjee S, Ghosh RN, Maxfield FR (1997) Endocytosis. Physiol Rev 77(3):759\u2013803. https:\/\/doi.org\/10.1152\/physrev.1997.77.3.759. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9234965","journal-title":"Physiol Rev"},{"issue":"39","key":"4_CR81","doi-asserted-by":"publisher","first-page":"13758","DOI":"10.1523\/JNEUROSCI.2649-11.2011","volume":"31","author":"DM Navaroli","year":"2011","unstructured":"Navaroli DM, Stevens ZH, Uzelac Z, Gabriel L, King MJ, Lifshitz LM, Sitte HH, Melikian HE (2011) The plasma membrane-associated GTPase Rin interacts with the dopamine transporter and is required for protein kinase C-regulated dopamine transporter trafficking. J Neurosci 31(39):13758\u201313770. https:\/\/doi.org\/10.1523\/JNEUROSCI.2649-11.2011. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21957239","journal-title":"J Neurosci"},{"issue":"3","key":"4_CR82","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1124\/jpet.109.159897","volume":"331","author":"AM Nelson","year":"2009","unstructured":"Nelson AM, Larson GA, Zahniser NR (2009) Low or high cocaine responding rats differ in striatal extracellular dopamine levels and dopamine transporter number. J Pharmacol Exp Ther 331(3):985\u2013997. https:\/\/doi.org\/10.1124\/jpet.109.159897. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19729579","journal-title":"J Pharmacol Exp Ther"},{"issue":"2","key":"4_CR83","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1523\/JNEUROSCI.16-02-00436.1996","volume":"16","author":"MJ Nirenberg","year":"1996","unstructured":"Nirenberg MJ, Vaughan RA, Uhl GR, Kuhar MJ, Pickel VM (1996) The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons. J Neurosci 16(2):436\u2013447. https:\/\/doi.org\/10.1523\/JNEUROSCI.16-02-00436.1996. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8551328","journal-title":"J Neurosci"},{"key":"4_CR84","doi-asserted-by":"publisher","unstructured":"O\u2019Sullivan MJ, Lindsay AJ (2020) The endosomal recycling pathway-at the crossroads of the cell. Int J Mol Sci 21(17). https:\/\/doi.org\/10.3390\/ijms21176074","DOI":"10.3390\/ijms21176074"},{"issue":"7474","key":"4_CR85","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1038\/nature12533","volume":"503","author":"A Penmatsa","year":"2013","unstructured":"Penmatsa A, Wang KH, Gouaux E (2013) X-ray structure of dopamine transporter elucidates antidepressant mechanism. Nature 503(7474):85\u201390. https:\/\/doi.org\/10.1038\/nature12533. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24037379","journal-title":"Nature"},{"issue":"3","key":"4_CR86","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1016\/S0022-3565(25)38838-5","volume":"269","author":"NS Pilotte","year":"1994","unstructured":"Pilotte NS, Sharpe LG, Kuhar MJ (1994) Withdrawal of repeated intravenous infusions of cocaine persistently reduces binding to dopamine transporters in the nucleus accumbens of Lewis rats. J Pharmacol Exp Ther 269(3):963\u2013969. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7912283","journal-title":"J Pharmacol Exp Ther"},{"issue":"2","key":"4_CR87","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1038\/nrm1313","volume":"5","author":"GJ Praefcke","year":"2004","unstructured":"Praefcke GJ, McMahon HT (2004) The dynamin superfamily: universal membrane tubulation and fission molecules? Nat Rev Mol Cell Biol 5(2):133\u2013147. https:\/\/doi.org\/10.1038\/nrm1313. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15040446","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"2","key":"4_CR88","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1016\/j.neulet.2008.02.021","volume":"435","author":"JJ Qian","year":"2008","unstructured":"Qian JJ, Cheng YB, Yang YP, Mao CJ, Qin ZH, Li K, Liu CF (2008) Differential effects of overexpression of wild-type and mutant human alpha-synuclein on MPP+-induced neurotoxicity in PC12 cells. Neurosci Lett 435(2):142\u2013146. https:\/\/doi.org\/10.1016\/j.neulet.2008.02.021. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18342443","journal-title":"Neurosci Lett"},{"key":"4_CR89","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2021.113267","volume":"408","author":"D Ragu Varman","year":"2021","unstructured":"Ragu Varman D, Subler MA, Windle JJ, Jayanthi LD, Ramamoorthy S (2021) Novelty-induced hyperactivity and suppressed cocaine induced locomotor activation in mice lacking threonine 53 phosphorylation of dopamine transporter. Behav Brain Res 408:113267. https:\/\/doi.org\/10.1016\/j.bbr.2021.113267. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33794225","journal-title":"Behav Brain Res"},{"issue":"5","key":"4_CR90","doi-asserted-by":"publisher","first-page":"1921","DOI":"10.1096\/fj.11-196113","volume":"26","author":"A Rao","year":"2012","unstructured":"Rao A, Richards TL, Simmons D, Zahniser NR, Sorkin A (2012) Epitope-tagged dopamine transporter knock-in mice reveal rapid endocytic trafficking and filopodia targeting of the transporter in dopaminergic axons. FASEB J 26(5):1921\u20131933. https:\/\/doi.org\/10.1096\/fj.11-196113. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22267337","journal-title":"FASEB J"},{"issue":"1","key":"4_CR91","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/j.mcn.2010.08.016","volume":"46","author":"A Rao","year":"2011","unstructured":"Rao A, Simmons D, Sorkin A (2011) Differential subcellular distribution of endosomal compartments and the dopamine transporter in dopaminergic neurons. Mol Cell Neurosci 46(1):148\u2013158. https:\/\/doi.org\/10.1016\/j.mcn.2010.08.016. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20816972","journal-title":"Mol Cell Neurosci"},{"issue":"2","key":"4_CR92","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1038\/s41380-021-01341-5","volume":"27","author":"MEA Reith","year":"2022","unstructured":"Reith MEA, Kortagere S, Wiers CE, Sun H, Kurian MA, Galli A, Volkow ND, Lin Z (2022) The dopamine transporter gene SLC6A3: multidisease risks. Mol Psychiatry 27(2):1031\u20131046. https:\/\/doi.org\/10.1038\/s41380-021-01341-5. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/34650206","journal-title":"Mol Psychiatry"},{"key":"4_CR93","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1038\/ncomms2568","volume":"4","author":"M Rickhag","year":"2013","unstructured":"Rickhag M, Hansen FH, Sorensen G, Strandfelt KN, Andresen B, Gotfryd K, Madsen KL, Vestergaard-Klewe I, Ammendrup-Johnsen I, Eriksen J, Newman AH, Fuchtbauer EM, Gomeza J, Woldbye DP, Wortwein G, Gether U (2013) A C-terminal PDZ domain-binding sequence is required for striatal distribution of the dopamine transporter. Nat Commun 4:1580. https:\/\/doi.org\/10.1038\/ncomms2568. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23481388","journal-title":"Nat Commun"},{"issue":"12","key":"4_CR94","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.1111\/tra.12335","volume":"16","author":"MS Robinson","year":"2015","unstructured":"Robinson MS (2015) Forty years of Clathrin-coated vesicles. Traffic 16(12):1210\u20131238. https:\/\/doi.org\/10.1111\/tra.12335. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26403691","journal-title":"Traffic"},{"issue":"16","key":"4_CR95","doi-asserted-by":"publisher","first-page":"5385","DOI":"10.1523\/jneurosci.6033-11.2012","volume":"32","author":"D Sakrikar","year":"2012","unstructured":"Sakrikar D, Mazei-Robison MS, Mergy MA, Richtand NW, Han Q, Hamilton PJ, Bowton E, Galli A, Veenstra-Vanderweele J, Gill M, Blakely RD (2012) Attention deficit\/hyperactivity disorder-derived coding variation in the dopamine transporter disrupts microdomain targeting and trafficking regulation. J Neurosci 32(16):5385\u20135397. https:\/\/doi.org\/10.1523\/jneurosci.6033-11.2012","journal-title":"J Neurosci"},{"issue":"1","key":"4_CR96","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1124\/jpet.107.130534","volume":"325","author":"DJ Samuvel","year":"2008","unstructured":"Samuvel DJ, Jayanthi LD, Manohar S, Kaliyaperumal K, See RE, Ramamoorthy S (2008) Dysregulation of dopamine transporter trafficking and function after abstinence from cocaine self-administration in rats: evidence for differential regulation in caudate putamen and nucleus accumbens. J Pharmacol Exp Ther 325(1):293\u2013301. https:\/\/doi.org\/10.1124\/jpet.107.130534. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18198344","journal-title":"J Pharmacol Exp Ther"},{"issue":"4","key":"4_CR97","doi-asserted-by":"publisher","first-page":"1413","DOI":"10.1523\/jneurosci.21-04-01413.2001","volume":"21","author":"V Sandoval","year":"2001","unstructured":"Sandoval V, Riddle EL, Ugarte YV, Hanson GR, Fleckenstein AE (2001) Methamphetamine-induced rapid and reversible changes in dopamine transporter function: an in vitro model. J Neurosci 21(4):1413\u20131419. https:\/\/doi.org\/10.1523\/jneurosci.21-04-01413.2001","journal-title":"J Neurosci"},{"issue":"12","key":"4_CR98","doi-asserted-by":"publisher","first-page":"6850","DOI":"10.1073\/pnas.110035297","volume":"97","author":"C Saunders","year":"2000","unstructured":"Saunders C, Ferrer JV, Shi L, Chen J, Merrill G, Lamb ME, Leeb-Lundberg LM, Carvelli L, Javitch JA, Galli A (2000) Amphetamine-induced loss of human dopamine transporter activity: an internalization-dependent and cocaine-sensitive mechanism. Proc Natl Acad Sci USA 97(12):6850\u20136855. https:\/\/doi.org\/10.1073\/pnas.110035297","journal-title":"Proc Natl Acad Sci USA"},{"key":"4_CR99","doi-asserted-by":"publisher","first-page":"9","DOI":"10.3389\/fnsyn.2016.00009","volume":"8","author":"L Schorova","year":"2016","unstructured":"Schorova L, Martin S (2016) Sumoylation in synaptic function and dysfunction. Front Synaptic Neurosci 8:9. https:\/\/doi.org\/10.3389\/fnsyn.2016.00009","journal-title":"Front Synaptic Neurosci"},{"key":"4_CR100","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1146\/annurev.neuro.28.061604.135722","volume":"30","author":"W Schultz","year":"2007","unstructured":"Schultz W (2007) Multiple dopamine functions at different time courses. Annu Rev Neurosci 30:259\u2013288. https:\/\/doi.org\/10.1146\/annurev.neuro.28.061604.135722. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17600522","journal-title":"Annu Rev Neurosci"},{"issue":"1","key":"4_CR101","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/0014-2999(91)90804-y","volume":"203","author":"LG Sharpe","year":"1991","unstructured":"Sharpe LG, Pilotte NS, Mitchell WM, De Souza EB (1991) Withdrawal of repeated cocaine decreases autoradiographic [3H]mazindol-labelling of dopamine transporter in rat nucleus accumbens. Eur J Pharmacol 203(1):141\u2013144. https:\/\/doi.org\/10.1016\/0014-2999(91)90804-y. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/1797552","journal-title":"Eur J Pharmacol"},{"issue":"10","key":"4_CR102","doi-asserted-by":"publisher","first-page":"1757","DOI":"10.1038\/s41386-021-01009-2","volume":"46","author":"JK Shaw","year":"2021","unstructured":"Shaw JK, Pamela Alonso I, Lewandowski SI, Scott MO, O\u2019Connor BM, Aggarwal S, De Biasi M, Mortensen OV, Espana RA (2021) Individual differences in dopamine uptake in the dorsomedial striatum prior to cocaine exposure predict motivation for cocaine in male rats. Neuropsychopharmacology 46(10):1757\u20131767. https:\/\/doi.org\/10.1038\/s41386-021-01009-2. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33953341","journal-title":"Neuropsychopharmacology"},{"key":"4_CR103","doi-asserted-by":"publisher","DOI":"10.1016\/j.crphys.2023.100106","volume":"6","author":"M Shetty","year":"2023","unstructured":"Shetty M, Bolland DE, Morrell J, Grove BD, Foster JD, Vaughan RA (2023) Dopamine transporter membrane mobility is bidirectionally regulated by phosphorylation and palmitoylation. Curr Res Physiol 6:100106. https:\/\/doi.org\/10.1016\/j.crphys.2023.100106. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/38107792","journal-title":"Curr Res Physiol"},{"issue":"2","key":"4_CR104","doi-asserted-by":"publisher","first-page":"1313","DOI":"10.1128\/mcb.19.2.1313","volume":"19","author":"JW Soh","year":"1999","unstructured":"Soh JW, Lee EH, Prywes R, Weinstein IB (1999) Novel roles of specific isoforms of protein kinase C in activation of the c-fos serum response element. Mol Cell Biol 19(2):1313\u20131324. https:\/\/doi.org\/10.1128\/mcb.19.2.1313","journal-title":"Mol Cell Biol"},{"issue":"6","key":"4_CR105","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2021.101361","volume":"297","author":"G Sorensen","year":"2021","unstructured":"Sorensen G, Rickhag M, Leo D, Lycas MD, Ridderstrom PH, Weikop P, Lilja JH, Rifes P, Herborg F, Woldbye D, Wortwein G, Gainetdinov RR, Fink-Jensen A, Gether U (2021) Disruption of the PDZ domain-binding motif of the dopamine transporter uniquely alters nanoscale distribution, dopamine homeostasis, and reward motivation. J Biol Chem 297(6):101361. https:\/\/doi.org\/10.1016\/j.jbc.2021.101361. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/34756883","journal-title":"J Biol Chem"},{"issue":"30","key":"4_CR106","doi-asserted-by":"publisher","first-page":"28274","DOI":"10.1074\/jbc.M210652200","volume":"278","author":"T Sorkina","year":"2003","unstructured":"Sorkina T, Doolen S, Galperin E, Zahniser NR, Sorkin A (2003) Oligomerization of dopamine transporters visualized in living cells by fluorescence resonance energy transfer microscopy. J Biol Chem 278(30):28274\u201328283. https:\/\/doi.org\/10.1074\/jbc.M210652200. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12746456","journal-title":"J Biol Chem"},{"issue":"2","key":"4_CR107","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1111\/j.1600-0854.2005.00259.x","volume":"6","author":"T Sorkina","year":"2005","unstructured":"Sorkina T, Hoover BR, Zahniser NR, Sorkin A (2005) Constitutive and protein kinase C-induced internalization of the dopamine transporter is mediated by a clathrin-dependent mechanism. Traffic 6(2):157\u2013170. https:\/\/doi.org\/10.1111\/j.1600-0854.2005.00259.x","journal-title":"Traffic"},{"key":"4_CR108","doi-asserted-by":"publisher","unstructured":"Sorkina T, Ma S, Larsen MB, Watkins SC, Sorkin A (2018) Small molecule induced oligomerization, clustering and clathrin-independent endocytosis of the dopamine transporter. elife 7. https:\/\/doi.org\/10.7554\/eLife.32293. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29630493","DOI":"10.7554\/eLife.32293"},{"issue":"31","key":"4_CR109","doi-asserted-by":"publisher","first-page":"8195","DOI":"10.1523\/jneurosci.1301-06.2006","volume":"26","author":"T Sorkina","year":"2006","unstructured":"Sorkina T, Miranda M, Dionne KR, Hoover BR, Zahniser NR, Sorkin A (2006) RNA interference screen reveals an essential role of Nedd4-2 in dopamine transporter ubiquitination and endocytosis. J Neurosci 26(31):8195\u20138205. https:\/\/doi.org\/10.1523\/jneurosci.1301-06.2006","journal-title":"J Neurosci"},{"issue":"5","key":"4_CR110","doi-asserted-by":"publisher","first-page":"1361","DOI":"10.1523\/jneurosci.3250-08.2009","volume":"29","author":"T Sorkina","year":"2009","unstructured":"Sorkina T, Richards TL, Rao A, Zahniser NR, Sorkin A (2009) Negative regulation of dopamine transporter endocytosis by membrane-proximal N-terminal residues. J Neurosci 29(5):1361\u20131374. https:\/\/doi.org\/10.1523\/jneurosci.3250-08.2009","journal-title":"J Neurosci"},{"issue":"3","key":"4_CR111","doi-asserted-by":"publisher","first-page":"1678","DOI":"10.1016\/S0022-3565(25)24057-5","volume":"271","author":"JK Staley","year":"1994","unstructured":"Staley JK, Hearn WL, Ruttenber AJ, Wetli CV, Mash DC (1994) High affinity cocaine recognition sites on the dopamine transporter are elevated in fatal cocaine overdose victims. J Pharmacol Exp Ther 271(3):1678\u20131685. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7996484","journal-title":"J Pharmacol Exp Ther"},{"issue":"18","key":"4_CR112","doi-asserted-by":"publisher","first-page":"16482","DOI":"10.1074\/jbc.M111.230037","volume":"286","author":"S Sucic","year":"2011","unstructured":"Sucic S, El-Kasaby A, Kudlacek O, Sarker S, Sitte HH, Marin P, Freissmuth M (2011) The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C. J Biol Chem 286(18):16482\u201316490. https:\/\/doi.org\/10.1074\/jbc.M111.230037. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21454670","journal-title":"J Biol Chem"},{"issue":"2","key":"4_CR113","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1038\/s41386-019-0457-x","volume":"45","author":"CG Sweeney","year":"2020","unstructured":"Sweeney CG, Kearney PJ, Fagan RR, Smith LA, Bolden NC, Zhao-Shea R, Rivera IV, Kolpakova J, Xie J, Gao G, Tapper AR, Martin GE, Melikian HE (2020) Conditional, inducible gene silencing in dopamine neurons reveals a sex-specific role for Rit2 GTPase in acute cocaine response and striatal function. Neuropsychopharmacology 45(2):384\u2013393. https:\/\/doi.org\/10.1038\/s41386-019-0457-x. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31277075","journal-title":"Neuropsychopharmacology"},{"issue":"4","key":"4_CR114","doi-asserted-by":"publisher","first-page":"2731","DOI":"10.1074\/jbc.M201926200","volume":"278","author":"GE Torres","year":"2003","unstructured":"Torres GE, Carneiro A, Seamans K, Fiorentini C, Sweeney A, Yao WD, Caron MG (2003) Oligomerization and trafficking of the human dopamine transporter. Mutational analysis identifies critical domains important for the functional expression of the transporter. J Biol Chem 278(4):2731\u20132739. https:\/\/doi.org\/10.1074\/jbc.M201926200. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12429746","journal-title":"J Biol Chem"},{"issue":"1","key":"4_CR115","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/s0896-6273(01)00267-7","volume":"30","author":"GE Torres","year":"2001","unstructured":"Torres GE, Yao WD, Mohn AR, Quan H, Kim KM, Levey AI, Staudinger J, Caron MG (2001) Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1. Neuron 30(1):121\u2013134. https:\/\/doi.org\/10.1016\/s0896-6273(01)00267-7. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11343649","journal-title":"Neuron"},{"key":"4_CR116","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2021.662216","volume":"15","author":"SM Underhill","year":"2021","unstructured":"Underhill SM, Amara SG (2021) Acetylcholine receptor stimulation activates protein Kinase C mediated internalization of the Dopamine transporter. Front Cell Neurosci 15:662216. https:\/\/doi.org\/10.3389\/fncel.2021.662216. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33897375","journal-title":"Front Cell Neurosci"},{"issue":"4","key":"4_CR117","doi-asserted-by":"publisher","first-page":"1208","DOI":"10.1038\/s41380-019-0469-2","volume":"26","author":"SM Underhill","year":"2021","unstructured":"Underhill SM, Hullihen PD, Chen J, Fenollar-Ferrer C, Rizzo MA, Ingram SL, Amara SG (2021) Amphetamines signal through intracellular TAAR1 receptors coupled to Galpha(13) and Galpha(S) in discrete subcellular domains. Mol Psychiatry 26(4):1208\u20131223. https:\/\/doi.org\/10.1038\/s41380-019-0469-2. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31399635","journal-title":"Mol Psychiatry"},{"issue":"6627","key":"4_CR118","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1038\/386830a0","volume":"386","author":"ND Volkow","year":"1997","unstructured":"Volkow ND, Wang GJ, Fowler JS, Logan J, Gatley SJ, Hitzemann R, Chen AD, Dewey SL, Pappas N (1997) Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects. Nature 386(6627):830\u2013833. https:\/\/doi.org\/10.1038\/386830a0. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9126741","journal-title":"Nature"},{"issue":"3","key":"4_CR119","doi-asserted-by":"publisher","first-page":"835","DOI":"10.1124\/mol.106.026351","volume":"71","author":"Y Wei","year":"2007","unstructured":"Wei Y, Williams JM, Dipace C, Sung U, Javitch JA, Galli A, Saunders C (2007) Dopamine transporter activity mediates amphetamine-induced inhibition of Akt through a Ca2+\/calmodulin-dependent kinase II-dependent mechanism. Mol Pharmacol 71(3):835\u2013842. https:\/\/doi.org\/10.1124\/mol.106.026351. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17164407","journal-title":"Mol Pharmacol"},{"issue":"3","key":"4_CR120","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1016\/s0304-3940(03)00097-1","volume":"340","author":"C Wersinger","year":"2003","unstructured":"Wersinger C, Sidhu A (2003) Attenuation of dopamine transporter activity by alpha-synuclein. Neurosci Lett 340(3):189\u2013192. https:\/\/doi.org\/10.1016\/s0304-3940(03)00097-1. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12672538","journal-title":"Neurosci Lett"},{"issue":"51","key":"4_CR121","doi-asserted-by":"publisher","first-page":"E7138","DOI":"10.1073\/pnas.1511670112","volume":"112","author":"DS Wheeler","year":"2015","unstructured":"Wheeler DS, Underhill SM, Stolz DB, Murdoch GH, Thiels E, Romero G, Amara SG (2015) Amphetamine activates Rho GTPase signaling to mediate dopamine transporter internalization and acute behavioral effects of amphetamine. Proc Natl Acad Sci USA 112(51):E7138\u2013E7147. https:\/\/doi.org\/10.1073\/pnas.1511670112. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26553986","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5 Pt 2","key":"4_CR122","doi-asserted-by":"publisher","first-page":"2966","DOI":"10.1523\/JNEUROSCI.14-05-02966.1994","volume":"14","author":"JM Wilson","year":"1994","unstructured":"Wilson JM, Nobrega JN, Carroll ME, Niznik HB, Shannak K, Lac ST, Pristupa ZB, Dixon LM, Kish SJ (1994) Heterogeneous subregional binding patterns of 3H-WIN 35,428 and 3H-GBR 12,935 are differentially regulated by chronic cocaine self-administration. J Neurosci 14(5 Pt 2):2966\u20132979. https:\/\/doi.org\/10.1523\/JNEUROSCI.14-05-02966.1994. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8182452","journal-title":"J Neurosci"},{"issue":"50","key":"4_CR123","doi-asserted-by":"publisher","first-page":"15480","DOI":"10.1073\/pnas.1512957112","volume":"112","author":"S Wu","year":"2015","unstructured":"Wu S, Bellve KD, Fogarty KE, Melikian HE (2015) Ack1 is a dopamine transporter endocytic brake that rescues a trafficking-dysregulated ADHD coding variant. Proc Natl Acad Sci USA 112(50):15480\u201315485. https:\/\/doi.org\/10.1073\/pnas.1512957112. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26621748","journal-title":"Proc Natl Acad Sci USA"},{"issue":"39","key":"4_CR124","doi-asserted-by":"publisher","first-page":"9438","DOI":"10.1523\/JNEUROSCI.3885-16.2017","volume":"37","author":"S Wu","year":"2017","unstructured":"Wu S, Fagan RR, Uttamapinant C, Lifshitz LM, Fogarty KE, Ting AY, Melikian HE (2017) The Dopamine transporter recycles via a Retromer-dependent Postendocytic mechanism: tracking studies using a novel fluorophore-coupling approach. J Neurosci 37(39):9438\u20139452. https:\/\/doi.org\/10.1523\/JNEUROSCI.3885-16.2017. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28847807","journal-title":"J Neurosci"},{"issue":"12","key":"4_CR125","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.1001\/jamapsychiatry.2022.3541","volume":"79","author":"LN Yatham","year":"2022","unstructured":"Yatham LN, Liddle PF, Gonzalez M, Saraf G, Vafai N, Lam RW, Sossi V (2022) A positron emission tomography study of Dopamine transporter density in patients with bipolar disorder with current Mania and those with recently remitted Mania. JAMA Psychiatry 79(12):1217\u20131224. https:\/\/doi.org\/10.1001\/jamapsychiatry.2022.3541","journal-title":"JAMA Psychiatry"},{"issue":"4","key":"4_CR126","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.semcdb.2009.01.004","volume":"20","author":"NR Zahniser","year":"2009","unstructured":"Zahniser NR, Sorkin A (2009) Trafficking of dopamine transporters in psychostimulant actions. Semin Cell Dev Biol 20(4):411\u2013417. https:\/\/doi.org\/10.1016\/j.semcdb.2009.01.004","journal-title":"Semin Cell Dev Biol"},{"issue":"49","key":"4_CR127","doi-asserted-by":"publisher","first-page":"35842","DOI":"10.1074\/jbc.M611758200","volume":"282","author":"A Zapata","year":"2007","unstructured":"Zapata A, Kivell B, Han Y, Javitch JA, Bolan EA, Kuraguntla D, Jaligam V, Oz M, Jayanthi LD, Samuvel DJ, Ramamoorthy S, Shippenberg TS (2007) Regulation of dopamine transporter function and cell surface expression by D3 dopamine receptors. J Biol Chem 282(49):35842\u201335854. https:\/\/doi.org\/10.1074\/jbc.M611758200. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17923483","journal-title":"J Biol Chem"}],"container-title":["Advances in Neurobiology","Monoamine Transporters"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-031-96364-3_4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T18:00:00Z","timestamp":1776794400000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-031-96364-3_4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025]]},"ISBN":["9783031963636","9783031963643"],"references-count":127,"URL":"https:\/\/doi.org\/10.1007\/978-3-031-96364-3_4","relation":{},"ISSN":["2190-5215","2190-5223"],"issn-type":[{"value":"2190-5215","type":"print"},{"value":"2190-5223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025]]},"assertion":[{"value":"7 October 2025","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}