{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T07:05:03Z","timestamp":1779433503034,"version":"3.53.1"},"publisher-location":"Cham","reference-count":280,"publisher":"Springer Nature Switzerland","isbn-type":[{"value":"9783031968822","type":"print"},{"value":"9783031968839","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026]]},"DOI":"10.1007\/978-3-031-96883-9_2","type":"book-chapter","created":{"date-parts":[[2025,11,9]],"date-time":"2025-11-09T16:12:47Z","timestamp":1762704767000},"page":"33-60","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comprehensive Approaches to Protein Detection and Analysis in Mycobacterium tuberculosis"],"prefix":"10.1007","author":[{"given":"Parissa","family":"Farnia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali Akbar","family":"Velayati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jalaledin","family":"Ghanavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poopak","family":"Farnia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,11,10]]},"reference":[{"key":"2_CR1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jctube.2024.100458","volume":"36","author":"S Abbasnia","year":"2024","unstructured":"Abbasnia S, Hashem Asnaashari AM, Sharebiani H, Soleimanpour S, Mosavat A, Rezaee SA (2024) Mycobacterium tuberculosis and host interactions in the manifestation of tuberculosis. J Clin Tubercul Other Mycobacter Dis 36:100458","journal-title":"J Clin Tubercul Other Mycobacter Dis"},{"key":"2_CR1036","doi-asserted-by":"crossref","unstructured":"Adeniji SE, Adalumo OB, Ekoja FO (2020) Anti-tubercular modelling, molecular docking simulation and insight toward computational design of novel compounds as potent antagonist against DNA gyrase receptor. Med Microecol 5:100020","DOI":"10.1016\/j.medmic.2020.100020"},{"key":"2_CR1033","doi-asserted-by":"crossref","unstructured":"Ahmad A, Rukmana A, Khairinisa MA, Pitaloka DAE, Agus R, Ladju RB et al (2025) Comprehensive review on the application of bio-immunoinformatics in the development of highly effective new candidate vaccines against tuberculosis. Karbala Int J Mod Sci 11(2):2. https:\/\/doi.org\/10.33640\/2405-609X.3399","DOI":"10.33640\/2405-609X.3399"},{"issue":"6","key":"2_CR3","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1080\/17460441.2017.1322579","volume":"12","author":"ATS Albanaz","year":"2017","unstructured":"Albanaz ATS, Rodrigues CHM, Pires DEV, Ascher DB (2017) Combating mutations in genetic disease and drug resistance: understanding molecular mechanisms to guide drug design. Expert Opin Drug Discov 12(6):553\u2013563","journal-title":"Expert Opin Drug Discov"},{"issue":"5","key":"2_CR4","doi-asserted-by":"publisher","first-page":"1180","DOI":"10.1074\/mcp.M112.018846","volume":"12","author":"J Albrethsen","year":"2013","unstructured":"Albrethsen J, Agner J, Piersma SR, H\u00f8jrup P, Pham TV, Weldingh K, Jimenez CR, Andersen P, Rosenkrands I (2013) Proteomic profiling of Mycobacterium tuberculosis identifies nutrient-starvation-responsive toxin-antitoxin systems. Mol Cell Proteomics 12(5):1180\u20131191","journal-title":"Mol Cell Proteomics"},{"key":"2_CR5","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1385\/1-59259-076-4:391","volume":"40","author":"AA Al-Tubuly","year":"2000","unstructured":"Al-Tubuly AA (2000) SDS-PAGE and Western blotting. Methods Mol Med 40:391\u2013405","journal-title":"Methods Mol Med"},{"issue":"10","key":"2_CR6","first-page":"933","volume":"12","author":"F Amalia","year":"2022","unstructured":"Amalia F, Syamsunarno MRAA, Triatin RD, Fatimah SN, Chaidir L, Achmad TH (2022) The role of amino acids in tuberculosis infection: a literature review. Meta 12(10):933","journal-title":"Meta"},{"key":"2_CR7","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1186\/s43556-024-00243-6","volume":"6","author":"Y An","year":"2025","unstructured":"An Y, Ni R, Zhuang L, Yang L, Ye Z, Li L, Parkkila S, Aspatwar A, Gong W (2025) Tuberculosis vaccines and therapeutic drug: challenges and future directions. Mol Biomed 6:4","journal-title":"Mol Biomed"},{"key":"2_CR8","first-page":"307","volume-title":"Tuberculosis: pathogenesis, protection, and control","author":"\u00c5B Andersen","year":"1994","unstructured":"Andersen \u00c5B, Brennan P (1994) Proteins and antigens of Mycobacterium tuberculosis. In: Bloom BR (ed) Tuberculosis: pathogenesis, protection, and control. ASM Press, pp 307\u2013332"},{"issue":"8","key":"2_CR9","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1038\/nrmicro1211","volume":"3","author":"P Andersen","year":"2005","unstructured":"Andersen P, Doherty TM (2005) The success and failure of BCG\u2014implications for a novel tuberculosis vaccine. Nat Rev Microbiol 3(8):656\u2013662","journal-title":"Nat Rev Microbiol"},{"issue":"2","key":"2_CR10","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1042\/bj0910222","volume":"91","author":"P Andrews","year":"1964","unstructured":"Andrews P (1964) Estimation of the molecular weights of proteins by Sephadex gel-filtration. Biochem J 91(2):222\u2013233","journal-title":"Biochem J"},{"key":"2_CR1003","doi-asserted-by":"crossref","unstructured":"Andrew SM, Titus JA, Zumstein L (2001) Dialysis and concentration of protein solutions. Curr Protoc Cell Biol. Appendix 3: Appendix 3C. https:\/\/doi.org\/10.1002\/0471143030.cba03cs04. PMID:18228285","DOI":"10.1002\/0471143030.cba03cs04"},{"key":"2_CR1004","doi-asserted-by":"crossref","unstructured":"Andrew SM, Titus JA, Zumstein L (2002) Dialysis and concentration of protein solutions. Curr Protoc Toxicol. Appendix 3:A.3H.1-5. https:\/\/doi.org\/10.1002\/0471140856.txa03hs10. PMID:20976673","DOI":"10.1002\/0471140856.txa03hs10"},{"issue":"1","key":"2_CR11","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.pep.2009.07.017","volume":"68","author":"M Aoki","year":"2009","unstructured":"Aoki M, Matsuda T, Tomo Y, Miyata Y, Inoue M, Kigawa T, Yokoyama S (2009) Automated system for high-throughput protein production using the dialysis cell-free method. Protein Expr Purif 68(1):128\u2013136","journal-title":"Protein Expr Purif"},{"key":"2_CR12","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.9643","volume":"8","author":"CL Ara\u00fajo","year":"2020","unstructured":"Ara\u00fajo CL, Blanco I, Souza L, Tiwari S, Pereira LC, Ghosh P, Azevedo V, Silva A, Folador A (2020) In silico functional prediction of hypothetical proteins from the core genome of Corynebacterium pseudotuberculosis biovar ovis. PeerJ 8:e9643","journal-title":"PeerJ"},{"issue":"5","key":"2_CR13","doi-asserted-by":"publisher","first-page":"1850","DOI":"10.1086\/315448","volume":"181","author":"SM Arend","year":"2000","unstructured":"Arend SM, Andersen P, van Meijgaarden KE, Skj\u00f8t RLV, Subronto YW, van Dissel JT, Ottenhoff THM (2000) Detection of active tuberculosis infection by T cell responses to early-secreted antigenic target 6-kDa protein and culture filtrate protein 10. J Infect Dis 181(5):1850\u20131854","journal-title":"J Infect Dis"},{"key":"2_CR14","doi-asserted-by":"publisher","first-page":"4742","DOI":"10.1038\/s41598-022-08359-x","volume":"12","author":"JMC Ar\u00e9valo","year":"2022","unstructured":"Ar\u00e9valo JMC, Amorim JC (2022) Virtual screening, optimization and molecular dynamics analyses highlighting a pyrrolo[1,2-a]quinazoline derivative as a potential inhibitor of DNA gyrase B of Mycobacterium tuberculosis. Sci Rep 12:4742","journal-title":"Sci Rep"},{"key":"2_CR1024","doi-asserted-by":"crossref","unstructured":"Asare P, Otchere ID, Bedeley E, Brites D, Loiseau C, Baddoo NA et al (2020) Whole genome sequencing and spatial analysis identifies recent tuberculosis transmission hotspots in Ghana. Front Med (Lausanne) 7:161. https:\/\/doi.org\/10.3389\/fmed.2020.00161. PMID:32509791; PMCID:PMC7248928","DOI":"10.3389\/fmed.2020.00161"},{"issue":"1","key":"2_CR15","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1186\/s12879-024-10224-3","volume":"24","author":"S Ayalew","year":"2024","unstructured":"Ayalew S, Wegayehu T, Wondale B, Tarekegn A, Tessema B, Admasu F, Piantadosi A, Sahi M, Gebresilase TT, Fredolini C, Mihret A (2024) Candidate serum protein biomarkers for active pulmonary tuberculosis diagnosis in tuberculosis endemic settings. BMC Infect Dis 24(1):1329","journal-title":"BMC Infect Dis"},{"issue":"7","key":"2_CR16","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1080\/23744235.2022.2047777","volume":"54","author":"F Bach","year":"2022","unstructured":"Bach F, Wejse C, Storgaard M, Patsche CB (2022) Is body height a prognostic marker for outcome of tuberculosis treatment? Infect Dis 54(7):538\u2013541","journal-title":"Infect Dis"},{"key":"2_CR17","volume-title":"Column chromatography","author":"O Bahadir","year":"2013","unstructured":"Bahadir O (2013) Ion-exchange chromatography and its applications. In: Martin MA (ed) Column chromatography. InTech"},{"key":"2_CR18","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1038\/msb.2008.63","volume":"4","author":"G Bal\u00e1zsi","year":"2008","unstructured":"Bal\u00e1zsi G, Heath AP, Shi L, Gennaro ML (2008) The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest. Mol Syst Biol 4:225","journal-title":"Mol Syst Biol"},{"issue":"4","key":"2_CR19","doi-asserted-by":"publisher","first-page":"417","DOI":"10.3390\/biology14040417","volume":"14","author":"O Barazani","year":"2025","unstructured":"Barazani O, Erdos T, Chowdhury R, Kaur G, Venketaraman V (2025) New advances in the development and design of Mycobacterium tuberculosis vaccines: construction and validation of multi-epitope vaccines for tuberculosis prevention. Biology 14(4):417","journal-title":"Biology"},{"issue":"4 Pt 1","key":"2_CR20","first-page":"394","volume":"123","author":"JA Bass","year":"1981","unstructured":"Bass JA, Serio RA (1981) The use of repeat skin tests to eliminate the booster phenomenon in serial tuberculin testing. Am Rev Respir Dis 123(4 Pt 1):394\u2013396","journal-title":"Am Rev Respir Dis"},{"key":"2_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2023.464208","volume":"1705","author":"J Beck","year":"2023","unstructured":"Beck J, Hochdaninger G, Carta G, Hahn R (2023) Resin structure impacts two-component protein adsorption and separation in anion exchange chromatography. J Chromatogr A 1705:464208","journal-title":"J Chromatogr A"},{"issue":"1","key":"2_CR23","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1021\/pr2007939","volume":"11","author":"C Bell","year":"2012","unstructured":"Bell C, Smith GT, Sweredoski MJ, Hess S (2012) Characterization of the Mycobacterium tuberculosis proteome by liquid chromatography mass spectrometry-based proteomics techniques: A comprehensive resource for tuberculosis research. J Proteome Res 11(1):119\u2013130","journal-title":"J Proteome Res"},{"issue":"2","key":"2_CR24","doi-asserted-by":"publisher","first-page":"581","DOI":"10.1128\/IAI.67.2.581-588.1999","volume":"67","author":"SI Bentley-Hibbert","year":"1999","unstructured":"Bentley-Hibbert SI, Quan X, Newman T, Huygen K, Godfrey HP (1999) Pathophysiology of antigen 85 in patients with active tuberculosis: antigen 85 circulates as complexes with fibronectin and immunoglobulin G. Infect Immun 67(2):581\u2013588","journal-title":"Infect Immun"},{"key":"2_CR25","doi-asserted-by":"publisher","first-page":"1120370","DOI":"10.3389\/fbinf.2023.1120370","volume":"3","author":"LMF Bertoline","year":"2023","unstructured":"Bertoline LMF, Lima AN, Krieger JE, Teixeira SK (2023) Before and after AlphaFold2: An overview of protein structure prediction. Frontiers in Bioinformatics 3:1120370","journal-title":"Frontiers in Bioinformatics"},{"key":"2_CR26","doi-asserted-by":"publisher","first-page":"3133","DOI":"10.1021\/acs.biochem.5b00114","volume":"54","author":"E Binshtein","year":"2015","unstructured":"Binshtein E, Ohi MD (2015) Cryo-electron microscopy and the amazing race to atomic resolution. Biochemistry 54:3133","journal-title":"Biochemistry"},{"key":"2_CR27","unstructured":"Bishi LY, Vedithi SC, Blundell TL, Mugumbate GC (2019) Computational deorphaning of Mycobacterium tuberculosis targets. In IntechOpen"},{"issue":"10","key":"2_CR28","doi-asserted-by":"publisher","first-page":"3977","DOI":"10.1007\/s00253-017-8291-8","volume":"101","author":"KM Bocian-Ostrzycka","year":"2017","unstructured":"Bocian-Ostrzycka KM, Grzeszczuk MJ, Bana\u015b AM, Jagusztyn-Krynicka EK (2017) Bacterial thiol oxidoreductases\u2014from basic research to new antibacterial strategies. Appl Microbiol Biotechnol 101(10):3977\u20133989","journal-title":"Appl Microbiol Biotechnol"},{"issue":"17","key":"2_CR29","doi-asserted-by":"publisher","first-page":"4579","DOI":"10.1016\/j.cell.2021.06.033","volume":"184","author":"B Bosch","year":"2021","unstructured":"Bosch B, DeJesus MA, Poulton NC, Zhang W, Engelhart CA, Zaveri A, Lavalette S, Ruecker N, Trujillo C, Wallach JB, Li S, Ehrt S, Chait BT, Schnappinger D, Rock JM (2021) Genome-wide gene expression tuning reveals diverse vulnerabilities of Mycobacterium tuberculosis. Cell 184(17):4579\u20134592.e24","journal-title":"Cell"},{"key":"2_CR30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2024.124039","volume":"1236","author":"M Briki","year":"2024","unstructured":"Briki M, Murisier A, Guidi M, Seydoux C, Buclin T, Marzolini C, Girardin FR, Thoma Y, Carrara S, Choong E, Decosterd LA (2024) Liquid chromatography coupled to tandem mass spectrometry (LC-MS\/MS) methods for the therapeutic drug monitoring of cytotoxic anticancer drugs: An update. J Chromatogr B 1236:124039","journal-title":"J Chromatogr B"},{"issue":"13","key":"2_CR31","doi-asserted-by":"publisher","first-page":"5596","DOI":"10.1073\/pnas.0700869104","volume":"104","author":"R Brosch","year":"2007","unstructured":"Brosch R, Gordon SV, Garnier T, Eiglmeier K, Frigui W, Valenti P, Dos Santos S, Duthoy S, Lacroix C, Garcia-Pelayo C, Inwald JK, Golby P, Garcia JN, Hewinson RG, Behr MA, Quail MA, Churcher C, Barrell BG, Parkhill J, Cole ST (2007) Genome plasticity of BCG and impact on vaccine efficacy. Proc Natl Acad Sci 104(13):5596\u20135601","journal-title":"Proc Natl Acad Sci"},{"issue":"1","key":"2_CR32","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/0003-2697(88)90555-6","volume":"174","author":"EG Brown","year":"1988","unstructured":"Brown EG (1988) Mixed anionic detergent\/aliphatic alcohol-polyacrylamide gel electrophoresis alters the separation of proteins relative to conventional sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Anal Biochem 174(1):337\u2013348","journal-title":"Anal Biochem"},{"key":"2_CR1019","doi-asserted-by":"crossref","unstructured":"Calder\u00f3n-Celis F, Cid-Barrio L, Encinar JR, Sanz-Medel A, Calvete JJ (2017) Absolute venomics: absolute quantification of intact venom proteins through elemental mass spectrometry. J Proteome 164:33\u201342","DOI":"10.1016\/j.jprot.2017.06.001"},{"issue":"1","key":"2_CR34","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1042\/BA20090358","volume":"57","author":"Z Cao","year":"2010","unstructured":"Cao Z, Feng Y, Wei H, Fang M, Hu X, Yu Y, Wang L, Wan M (2010) Purification of clinical-grade recombinant HSP65-MUC1 fusion protein. Biotechnol Appl Biochem 57(1):9\u201315","journal-title":"Biotechnol Appl Biochem"},{"key":"2_CR35","doi-asserted-by":"crossref","unstructured":"Cao T, Lyu L, Jia H, Wang J, Du F, Pan L, Li Z, Xing A, Xiao J, Ma Y, Zhang Z (2019) A two-way proteome microarray strategy to identify novel Mycobacterium tuberculosis-human interactors. Front Cell Infect Microbiol 9:65. https:\/\/doi.org\/10.3389\/fcimb.2019.00065. PMID:30984625; PMCID:PMC6448480","DOI":"10.3389\/fcimb.2019.00065"},{"key":"2_CR36","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.760468","volume":"12","author":"C Carranza","year":"2021","unstructured":"Carranza C, Herrera MT, Guzm\u00e1n-Beltr\u00e1n S, Salgado-Cant\u00fa MG, Salido-Guadarrama I, Santiago E, Ch\u00e1vez-Gal\u00e1n L, Guti\u00e9rrez-Gonz\u00e1lez LH, Gonz\u00e1lez Y (2021) A dual marker for monitoring MDR-TB treatment: host-derived miRNAs and M. tuberculosis-derived RNA sequences in serum. Front Immunol 12:760468","journal-title":"Front Immunol"},{"key":"2_CR37","doi-asserted-by":"publisher","first-page":"158","DOI":"10.3389\/fcimb.2018.00158","volume":"8","author":"Q Chai","year":"2018","unstructured":"Chai Q, Zhang Y, Liu CH (2018) Mycobacterium tuberculosis: an adaptable pathogen associated with multiple human diseases. Front Cell Infect Microbiol 8:158","journal-title":"Front Cell Infect Microbiol"},{"key":"2_CR38","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1038\/s41423-020-0502-z","volume":"17","author":"Q Chai","year":"2020","unstructured":"Chai Q, Wang L, Liu CH, Ge B (2020) New insights into the evasion of host innate immunity by Mycobacterium tuberculosis. Cell Mol Immunol 17:901\u2013913","journal-title":"Cell Mol Immunol"},{"issue":"1","key":"2_CR39","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1186\/s43141-023-00613-7","volume":"21","author":"V Chakma","year":"2023","unstructured":"Chakma V, Barman DN, Das SC, Hossain A, Momin MB, Tasneem M, Gupta SD (2023) In silico analysis of a novel hypothetical protein (YP_498675.1) from Staphylococcus aureus unravels the protein of tryptophan synthase beta superfamily (try-synth-beta_II). J Genet Eng Biotechnol 21(1):135","journal-title":"J Genet Eng Biotechnol"},{"issue":"1","key":"2_CR40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.cpan.2024.11.001","volume":"21","author":"J Chen","year":"2024","unstructured":"Chen J, Lin A, Luo P (2024) Advancing pharmaceutical research: A comprehensive review of cutting-edge tools and technologies. Curr Pharm Anal 21(1):1\u201319","journal-title":"Curr Pharm Anal"},{"key":"2_CR1039","doi-asserted-by":"crossref","unstructured":"Chen Y, Zhang X, Liang J, Jiang Q, Peierdun M, Xu P, Takiff HE, Gao Q (2025) Advantages of updated WHO mutation catalog combined with existing whole-genome sequencing-based approaches for mycobacterium tuberculosis resistance prediction. Genome Med 17:31. https:\/\/doi.org\/10.1186\/s13073-025-01458-0","DOI":"10.1186\/s13073-025-01458-0"},{"key":"2_CR41","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1016\/j.cell.2015.03.050","volume":"161","author":"Y Cheng","year":"2015","unstructured":"Cheng Y, Grigorieff N, Penczek PA, Walz T (2015) A primer to single-particle cryo-electron microscopy. Cell. 23;161(3):438-449 161:438","journal-title":"Cell"},{"key":"2_CR42","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1186\/1471-2164-15-308","volume":"15","author":"EN Chernyaeva","year":"2014","unstructured":"Chernyaeva EN, Shulgina MV, Rotkevich MS, Dobrynin PV, Simonov SA, Shitikov EA, Ischenko DS, Karpova IY, Kostryukova ES, Ilina EN, Govorun VM, Zhuravlev VY, Manicheva OA, Yablonsky PK, Isaeva YD, Nosova EY, Mokrousov IV, Vyazovaya AA, Narvskaya OV, Lapidus AL, O\u2019Brien SJ (2014) Genome-wide Mycobacterium tuberculosis variation (GMTV) database: A new tool for integrating sequence variations and epidemiology. BMC Genomics 15:308","journal-title":"BMC Genomics"},{"issue":"2","key":"2_CR43","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.tube.2010.11.009","volume":"91","author":"N Chim","year":"2011","unstructured":"Chim N, Habel JE, Johnston JM, Krieger I, Miallau L, Sankaranarayanan R, Morse RP, Bruning J, Swanson S, Kim H, Kim CY, Li H, Bulloch EM, Payne RJ, Manos-Turvey A, Hung LW, Baker EN, Lott JS, James MN, Terwilliger TC, Eisenberg DS, Sacchettini JC, Goulding CW (2011) The TB structural genomics consortium: A decade of progress. Tuberculosis 91(2):155\u2013172","journal-title":"Tuberculosis"},{"key":"2_CR44","doi-asserted-by":"publisher","first-page":"6267","DOI":"10.1038\/ncomms7267","volume":"6","author":"E Choudhary","year":"2015","unstructured":"Choudhary E, Thakur P, Pareek M, Agarwal N (2015) Gene silencing by CRISPR interference in mycobacteria. Nat Commun 6:6267","journal-title":"Nat Commun"},{"key":"2_CR45","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1186\/s13073-019-0660-8","volume":"11","author":"KA Cohen","year":"2019","unstructured":"Cohen KA, Manson AL, Desjardins CA, Abeel T, Earl AM (2019) Deciphering drug resistance in Mycobacterium tuberculosis using whole-genome sequencing: Progress, promise, and challenges. Genome Med 11:45","journal-title":"Genome Med"},{"key":"2_CR1008","doi-asserted-by":"crossref","unstructured":"Collazos J, Mart\u00ednez E, Mayo J (1999) Evolution of serum beta2-microglobulin concentrations during treatment of tuberculosis patients. Scand J Infect Dis 31(3):265\u2013267. https:\/\/doi.org\/10.1080\/00365549950163554. PMID:10482055","DOI":"10.1080\/00365549950163554"},{"issue":"1","key":"2_CR47","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1136\/jnnp.25.1.79","volume":"25","author":"J Colover","year":"1962","unstructured":"Colover J, Kremer M, Lovelace RE, Silver JR (1962) Effect of intrathecal purified protein derivative of tuberculin in multiple sclerosis. J Neurol Neurosurg Psychiatry 25(1):79\u201385","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2_CR48","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/978-1-4939-6412-3_2","volume":"1485","author":"PM Cummins","year":"2017","unstructured":"Cummins PM, O\u2019Connor BF, \u00d3\u2019F\u00e1g\u00e1in C (2017a) Gel-filtration chromatography. Methods Mol Biol 1485:15\u201325","journal-title":"Methods Mol Biol"},{"key":"2_CR49","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1007\/978-1-4939-6412-3_11","volume":"1485","author":"PM Cummins","year":"2017","unstructured":"Cummins PM, Rochfort KD, O\u2019Connor BF (2017b) Ion-exchange chromatography: basic principles and application. Methods Mol Biol 1485:209\u2013223","journal-title":"Methods Mol Biol"},{"key":"2_CR50","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1007\/978-1-4939-6412-3_18","volume":"1485","author":"PM Cummins","year":"2017","unstructured":"Cummins PM, Rochfort KD, O\u2019Connor BF (2017c) Hydrophobic interaction chromatography. Methods Mol Biol 1485:355\u2013363","journal-title":"Methods Mol Biol"},{"issue":"1","key":"2_CR51","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.tube.2009.12.002","volume":"90","author":"J Day","year":"2010","unstructured":"Day J, Schlesinger L, Friedman A (2010) Tuberculosis research: going forward with a powerful \"translational systems biology\" approach. Tuberculosis 90(1):1\u20138","journal-title":"Tuberculosis"},{"key":"2_CR1034","doi-asserted-by":"crossref","unstructured":"de Azevedo WF Jr (2011) Protein targets for development of drugs against mycobacterium tuberculosis. Curr Med Chem 18(9):1255\u20131257. https:\/\/doi.org\/10.2174\/092986711795029564. PMID:21366537","DOI":"10.2174\/092986711795029564"},{"issue":"Pt 7","key":"2_CR52","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1099\/00221287-146-7-1513","volume":"146","author":"J De Bruyn","year":"2000","unstructured":"De Bruyn J, Soetaert K, Buyssens P, Calonne I, De Coene JL, Gallet X, Brasseur R, Wattiez R, Falmagne P, Montrozier H, Lan\u00e9elle MA, Daff\u00e9 M (2000) Evidence for specific and non-covalent binding of lipids to natural and recombinant Mycobacterium bovis BCG hsp60 proteins, and to the Escherichia coli homologue GroEL. Microbiology 146(Pt 7):1513\u20131524","journal-title":"Microbiology"},{"key":"2_CR53","doi-asserted-by":"publisher","first-page":"922","DOI":"10.3389\/fgene.2019.00922","volume":"10","author":"W Deelder","year":"2019","unstructured":"Deelder W, Christakoudi S, Phelan J, Benavente ED, Campino S, McNerney R, Palla L, Clark TG (2019) Machine learning predicts accurately Mycobacterium tuberculosis drug resistance from whole genome sequencing data. Front Genet 10:922","journal-title":"Front Genet"},{"issue":"Suppl 2","key":"2_CR54","first-page":"S2","volume":"27","author":"R Dell\u2019Aquila","year":"2007","unstructured":"Dell\u2019Aquila R, Rodighiero MP, Ronco C (2007) Advances in the technology of automated, tidal, and continuous flow peritoneal dialysis. Perit Dial Int 27(Suppl 2):S2\u2013S6","journal-title":"Perit Dial Int"},{"issue":"6","key":"2_CR55","doi-asserted-by":"publisher","first-page":"2317","DOI":"10.1016\/j.celrep.2014.11.023","volume":"9","author":"J Deng","year":"2014","unstructured":"Deng J, Bi L, Zhou L, Guo SJ, Fleming J, Jiang HW, Zhou Y, Gu J, Zhong Q, Wang ZX, Liu Z, Deng RP, Gao J, Chen T, Li W, Wang JF, Wang X, Li H, Ge F, Zhu G, Zhang HN, Gu J, Wu FL, Zhang Z, Wang D, Hang H, Li Y, Cheng L, He X, Tao SC, Zhang XE (2014) Mycobacterium tuberculosis proteome microarray for global studies of protein function and immunogenicity. Cell Rep 9(6):2317\u20132329","journal-title":"Cell Rep"},{"issue":"2","key":"2_CR56","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1006\/prep.2001.1569","volume":"24","author":"KR Devi","year":"2002","unstructured":"Devi KR, Kumar KS, Ramalingam B, Alamelu R (2002) Purification and characterization of three immunodominant proteins (38, 30, and 16 kDa) of Mycobacterium tuberculosis. Protein Expr Purif 24(2):188\u2013195","journal-title":"Protein Expr Purif"},{"key":"2_CR1031","doi-asserted-by":"crossref","unstructured":"Devlin KL, Leach DT, Stratton KG, Lamichhane G, Lin VS, Beatty KE (2025) Proteomic characterization of mycobacterium tuberculosis subjected to carbon starvation. mSystems 10(5). e0153024, https:\/\/doi.org\/10.1128\/msystems.01530-24. PMID:40231840; PMCID:PMC12090744","DOI":"10.1128\/msystems.01530-24"},{"issue":"3","key":"2_CR57","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/S0092-1157(77)80004-8","volume":"5","author":"R Dobbelaer","year":"1977","unstructured":"Dobbelaer R, Knops J, Meulepas E, Uydebrouck M (1977) Standardization of a PPD preparation in Guinea-pigs and in man. J Biol Stand 5(3):187\u2013195","journal-title":"J Biol Stand"},{"issue":"8","key":"2_CR58","doi-asserted-by":"publisher","first-page":"2846","DOI":"10.1128\/iai.63.8.2846-2853.1995","volume":"63","author":"KM Dobos","year":"1995","unstructured":"Dobos KM, Swiderek K, Khoo KH, Brennan PJ, Belisle JT (1995) Evidence for glycosylation sites on the 45-kilodalton glycoprotein of Mycobacterium tuberculosis. Infect Immun 63(8):2846\u20132853","journal-title":"Infect Immun"},{"issue":"1","key":"2_CR60","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.micres.2010.01.005","volume":"166","author":"J Dresler","year":"2011","unstructured":"Dresler J, Klimentova J, Stulik J (2011) Bacterial protein complexes investigation using blue native PAGE. Microbiol Res 166(1):47\u201362","journal-title":"Microbiol Res"},{"issue":"10","key":"2_CR61","doi-asserted-by":"publisher","first-page":"1576","DOI":"10.1002\/pmic.201100523","volume":"12","author":"WH Dunham","year":"2012","unstructured":"Dunham WH, Mullin M, Gingras AC (2012) Affinity-purification coupled to mass spectrometry: basic principles and strategies. Proteomics 12(10):1576\u20131590","journal-title":"Proteomics"},{"key":"2_CR62","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/B978-0-12-420119-4.00007-0","volume":"541","author":"KC Duong-Ly","year":"2014","unstructured":"Duong-Ly KC, Gabelli SB (2014) Salting out of proteins using ammonium sulfate precipitation. Methods Enzymol 541:85\u201394","journal-title":"Methods Enzymol"},{"key":"2_CR63","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.tube.2017.01.005","volume":"103","author":"S Ekins","year":"2017","unstructured":"Ekins S, Godbole AA, K\u00e9ri G, Orfi L, Pato J, Bhat RS, Verma R, Bradley EK, Nagaraja V (2017) Machine learning and docking models for Mycobacterium tuberculosis topoisomerase I. Tuberculosis 103:52\u201360","journal-title":"Tuberculosis"},{"key":"2_CR1037","doi-asserted-by":"crossref","unstructured":"Elsaman T, Mohamed MA, Mohamed MS, Eltayib EM, Abdalla AE (2025) Microbial-based natural products as potential inhibitors targeting DNA gyrase B of mycobacterium tuberculosis: an in silico study. Front Chem 13:1524607. https:\/\/doi.org\/10.3389\/fchem.2025.1524607. PMID:39917046; PMCID:PMC11798933","DOI":"10.3389\/fchem.2025.1524607"},{"key":"2_CR1014","doi-asserted-by":"crossref","unstructured":"Esposito C, Cantisani M, D\u2019Auria G, Falcigno L, Pedone E, Galdiero S, Berisio R (2012) Mapping key interactions in the dimerization process of HBHA from mycobacterium tuberculosis: insights into bacterial agglutination. FEBS Lett 586(6):659\u2013667. https:\/\/doi.org\/10.1016\/j.febslet.2012.01.047. PMID:22306117","DOI":"10.1016\/j.febslet.2012.01.047"},{"key":"2_CR64","doi-asserted-by":"crossref","unstructured":"Eswar N, Webb B, Marti-Renom MA, Madhusudhan MS, Eramian D, Shen MY, Pieper U, Sali A (2006) Comparative protein structure modeling using Modeller. Curr Protoc Bioinform. Chapter 5:unit 5.6","DOI":"10.1002\/0471250953.bi0506s15"},{"issue":"11\u201312","key":"2_CR65","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1002\/ansa.202200058","volume":"3","author":"RE Ewonde","year":"2022","unstructured":"Ewonde RE, Lingg N, E\u00dfer D, Eeltink S (2022) A protocol for setting-up robust hydrophobic interaction chromatography targeting the analysis of intact proteins and monoclonal antibodies. Analytical Science Advances 3(11\u201312):304\u2013312","journal-title":"Analytical Science Advances"},{"issue":"11","key":"2_CR66","doi-asserted-by":"publisher","first-page":"2399","DOI":"10.1080\/07391102.2015.1117397","volume":"34","author":"Z Fakhar","year":"2016","unstructured":"Fakhar Z, Naiker S, Alves CN, Govender T, Maguire GE, Lameira J, Lamichhane G, Kruger HG, Honarparvar B (2016) A comparative modeling and molecular docking study on Mycobacterium tuberculosis targets involved in peptidoglycan biosynthesis. J Biomol Struct Dyn 34(11):2399\u20132417","journal-title":"J Biomol Struct Dyn"},{"issue":"24","key":"2_CR67","first-page":"4296","volume":"11","author":"S Falvo","year":"2011","unstructured":"Falvo S, Di Carli M, Desiderio A, Benvenuto E, Moglia A, America T, Lanteri S, Acquadro A (2011) 2-D DIGE analysis of UV-C radiation-responsive proteins in globe artichoke leaves. Proteomics 11(24):4296\u20134309","journal-title":"Proteomics"},{"key":"2_CR68","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/S0021-9673(01)91654-1","volume":"317","author":"JL Fausnaugh","year":"1984","unstructured":"Fausnaugh JL, Kennedy LA, Regnier FE (1984) Comparison of hydrophobic-interaction and reversed-phase chromatography of proteins. J Chromatogr A 317:141\u2013155","journal-title":"J Chromatogr A"},{"key":"2_CR69","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.jpba.2016.04.004","volume":"130","author":"S Fekete","year":"2016","unstructured":"Fekete S, Veuthey JL, Beck A, Guillarme D (2016) Hydrophobic interaction chromatography for the characterization of monoclonal antibodies and related products. J Pharm Biomed Anal 130:3\u201318","journal-title":"J Pharm Biomed Anal"},{"key":"2_CR70","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1186\/1471-2105-15-107","volume":"15","author":"JP Flandrois","year":"2014","unstructured":"Flandrois JP, Lina G, Dumitrescu O (2014) MUBII-TB-DB: A database of mutations associated with antibiotic resistance in Mycobacterium tuberculosis. BMC Bioinform 15:107","journal-title":"BMC Bioinform"},{"issue":"2","key":"2_CR71","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2021.100990","volume":"297","author":"N Fleck","year":"2021","unstructured":"Fleck N, Grundner C (2021) A Cas12a-based CRISPR interference system for multigene regulation in mycobacteria. J Biol Chem 297(2):100990","journal-title":"J Biol Chem"},{"issue":"6","key":"2_CR72","doi-asserted-by":"publisher","first-page":"2926","DOI":"10.1128\/IAI.70.6.2926-2932.2002","volume":"70","author":"DC Flyer","year":"2002","unstructured":"Flyer DC, Ramakrishna V, Miller C, Myers H, McDaniel M, Root K, Flournoy C, Engelhard VH, Canaday DH, Marto JA, Ross MM (2002) Identification by mass spectrometry of CD8+-T-cell Mycobacterium tuberculosis epitopes within the Rv0341 gene product. Infect Immun 70(6):2926\u20132932","journal-title":"Infect Immun"},{"key":"2_CR73","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1038\/nprot.2017.004","volume":"12","author":"J Frank","year":"2017","unstructured":"Frank J (2017) Advances in the field of single-particle cryo-electron microscopy over the last decade. Nat Protoc 12:209\u2013212","journal-title":"Nat Protoc"},{"issue":"9","key":"2_CR74","doi-asserted-by":"publisher","first-page":"3789","DOI":"10.1021\/pr800233r","volume":"7","author":"C Fu","year":"2008","unstructured":"Fu C, Hu J, Liu T, Ago T, Sadoshima J, Li H (2008) Quantitative analysis of redox-sensitive proteome with DIGE and ICAT. J Proteome Res 7(9):3789\u20133802","journal-title":"J Proteome Res"},{"issue":"1","key":"2_CR75","doi-asserted-by":"publisher","first-page":"8.4.1\u20138.4.37","DOI":"10.1002\/0471142735.im0804s75","volume":"75","author":"SR Gallagher","year":"2006","unstructured":"Gallagher SR (2006) One-dimensional SDS gel electrophoresis of proteins. Curr Protoc Immunol 75(1):8.4.1\u20138.4.37","journal-title":"Curr Protoc Immunol"},{"issue":"1","key":"2_CR76","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1038\/sj.icb.7100117","volume":"86","author":"N Ganguly","year":"2008","unstructured":"Ganguly N, Giang PH, Gupta C, Basu SK, Siddiqui I, Salunke DM, Sharma P (2008) Mycobacterium tuberculosis secretory proteins CFP-10, ESAT-6 and the CFP10:ESAT6 complex inhibit lipopolysaccharide-induced NF-\u03baB transactivation by downregulation of reactive oxidative species (ROS) production. Immunol Cell Biol 86(1):98\u2013106","journal-title":"Immunol Cell Biol"},{"key":"2_CR77","volume-title":"Mass spectrometer","author":"E Garg","year":"2024","unstructured":"Garg E, Zubair M (2024) Mass spectrometer. StatPearls Publishing, In StatPearls. Retrieved from https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK574559\/"},{"issue":"1","key":"2_CR78","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1128\/CVI.00208-09","volume":"17","author":"S Gaseitsiwe","year":"2010","unstructured":"Gaseitsiwe S, Valentini D, Mahdavifar S, Reilly M, Ehrnst A, Maeurer M (2010) Peptide microarray-based identification of Mycobacterium tuberculosis epitope binding to HLA-DRB10101, DRB11501, and DRB10401. Clin Vaccine Immunol 17(1):168\u2013175","journal-title":"Clin Vaccine Immunol"},{"issue":"3","key":"2_CR79","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1111\/j.1574-6976.2012.00331.x","volume":"36","author":"M Gengenbacher","year":"2012","unstructured":"Gengenbacher M, Kaufmann SH (2012) Mycobacterium tuberculosis: success through dormancy. FEMS Microbiol Rev 36(3):514\u2013532","journal-title":"FEMS Microbiol Rev"},{"issue":"2\u20133","key":"2_CR80","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1007\/s12026-011-8229-7","volume":"50","author":"HP Gideon","year":"2011","unstructured":"Gideon HP, Flynn JL (2011) Latent tuberculosis: what the host \u201csees\u201d? Immunol Res 50(2\u20133):202\u2013212","journal-title":"Immunol Res"},{"key":"2_CR1017","doi-asserted-by":"crossref","unstructured":"Gnanasekaran P, Pappu HR (2023) Affinity purification-mass spectrometry (AP-MS) and co-immunoprecipitation (co-IP) technique to study protein-protein interactions. Methods Mol Biol 2690:81\u201385. https:\/\/doi.org\/10.1007\/978-1-0716-3327-4_7. PMID:37450138","DOI":"10.1007\/978-1-0716-3327-4_7"},{"issue":"2","key":"2_CR81","doi-asserted-by":"publisher","first-page":"6568","DOI":"10.4081\/idr.2016.6568","volume":"8","author":"D Goletti","year":"2016","unstructured":"Goletti D, Petruccioli E, Joosten SA, Ottenhoff TH (2016) Tuberculosis biomarkers: from diagnosis to protection. Infect Dis Reports 8(2):6568","journal-title":"Infect Dis Reports"},{"issue":"5","key":"2_CR82","doi-asserted-by":"publisher","first-page":"bbac256","DOI":"10.1093\/bib\/bbac256","volume":"23","author":"PJ G\u00f3mez-Gonz\u00e1lez","year":"2022","unstructured":"G\u00f3mez-Gonz\u00e1lez PJ, Campino S, Phelan JE, Clark TG (2022) Portable sequencing of Mycobacterium tuberculosis for clinical and epidemiological applications. Brief Bioinform 23(5):bbac256","journal-title":"Brief Bioinform"},{"issue":"3\u20134","key":"2_CR83","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1159\/000169116","volume":"17","author":"CW Gottschalk","year":"1997","unstructured":"Gottschalk CW, Fellner SK (1997) (1997). History of the science of dialysis. Am J Nephrol 17(3\u20134):289\u2013298","journal-title":"Am J Nephrol"},{"issue":"1","key":"2_CR84","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/S0021-9673(01)85930-6","volume":"28","author":"KA Granath","year":"1967","unstructured":"Granath KA, Kvist BE (1967) Molecular weight distribution analysis by gel chromatography on Sephadex. J Chromatogr A 28(1):69\u201381","journal-title":"J Chromatogr A"},{"issue":"5","key":"2_CR85","first-page":"845","volume":"19","author":"J Guld","year":"1958","unstructured":"Guld J, Bentzon MW, Bleiker MA, Griep WA, Magnusson M, Waaler H (1958) Standardization of a new batch of purified tuberculin (PPD) intended for international use. Bull World Health Organ 19(5):845\u2013951","journal-title":"Bull World Health Organ"},{"key":"2_CR1010","doi-asserted-by":"crossref","unstructured":"Guttman A, Nolan J (1994) Comparison of the separation of proteins by sodium dodecyl sulfate-slab gel electrophoresis and capillary sodium dodecyl sulfate-gel electrophoresis. Anal Biochem 221(2):285\u2013289","DOI":"10.1006\/abio.1994.1413"},{"key":"2_CR1015","doi-asserted-by":"crossref","unstructured":"Gygi SP, Aebersold R (2000) Mass spectrometry and proteomics. Curr Opin Chem Biol 4(5):489\u2013494. https:\/\/doi.org\/10.1016\/s1367-5931(00)00121-6. PMID:11006534","DOI":"10.1016\/S1367-5931(00)00121-6"},{"key":"2_CR86","doi-asserted-by":"crossref","unstructured":"Hagel L (2001) Gel-filtration chromatography. Current protocols in protein science, chapter 8, unit 8.3","DOI":"10.1038\/npg.els.0002676"},{"issue":"5","key":"2_CR87","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1097\/00043764-199905000-00007","volume":"41","author":"KM Hallak","year":"1999","unstructured":"Hallak KM, Schenk M, Neale AV (1999) Evaluation of the two-step tuberculin skin test in health care workers at an inner-city medical center. J Occup Environ Med 41(5):393\u2013396","journal-title":"J Occup Environ Med"},{"issue":"3","key":"2_CR88","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1002\/mrm.1910130319","volume":"13","author":"D Hoffman","year":"1990","unstructured":"Hoffman D, Venters R, Franks S, Spicer L (1990) Use of gel filtration in the preparation of biological fluids for magnetic resonance spectroscopy. Magn Reson Med 13(3):507\u2013513","journal-title":"Magn Reson Med"},{"issue":"9","key":"2_CR89","first-page":"461","volume":"92","author":"G Horner","year":"1965","unstructured":"Horner G, Elliott GB (1965) An immuno-electrophoretic apparatus: studies in tuberculosis. Can Med Assoc J 92(9):461\u2013464","journal-title":"Can Med Assoc J"},{"issue":"2","key":"2_CR90","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1111\/j.1365-2958.2012.08206.x","volume":"86","author":"EN Houben","year":"2012","unstructured":"Houben EN, Bestebroer J, Ummels R, Wilson L, Piersma SR, Jim\u00e9nez CR, Ottenhoff TH, Luirink J, Bitter W (2012) Composition of the type VII secretion system membrane complex. Mol Microbiol 86(2):472\u2013484","journal-title":"Mol Microbiol"},{"issue":"8","key":"2_CR91","first-page":"1707","volume":"1843","author":"EN Houben","year":"2014","unstructured":"Houben EN, Korotkov KV, Bitter W (2014) Take five\u2014type VII secretion systems of Mycobacteria. Biochimica et Biophysica Acta (BBA) \u2013 molecular. Cell Res 1843(8):1707\u20131716","journal-title":"Cell Res"},{"key":"2_CR1029","doi-asserted-by":"crossref","unstructured":"Hudock TA, Foreman TW, Bandyopadhyay N, Gautam US, Veatch AV, DN LB et al (2017) Hypoxia sensing and persistence genes are expressed during the intragranulomatous survival of mycobacterium tuberculosis. Am J Respir Cell Mol Biol 56(5):637\u2013647. https:\/\/doi.org\/10.1165\/rcmb.2016-0239OC. PMID:28135421; PMCID:PMC5449490","DOI":"10.1165\/rcmb.2016-0239OC"},{"issue":"6","key":"2_CR92","doi-asserted-by":"publisher","first-page":"968","DOI":"10.1093\/clinids\/17.6.968","volume":"17","author":"RE Huebner","year":"1993","unstructured":"Huebner RE, Schein MF, Bass JB Jr (1993) The tuberculin skin test. Clin Infect Dis 17(6):968\u2013975","journal-title":"Clin Infect Dis"},{"key":"2_CR93","doi-asserted-by":"publisher","first-page":"321","DOI":"10.3389\/fimmu.2014.00321","volume":"5","author":"K Huygen","year":"2014","unstructured":"Huygen K (2014) The immunodominant T-cell epitopes of the mycolyl-transferases of the antigen 85 complex of Mycobacterium tuberculosis. Front Immunol 5:321","journal-title":"Front Immunol"},{"key":"2_CR94","doi-asserted-by":"publisher","first-page":"5487","DOI":"10.1038\/s41598-020-62368-2","volume":"10","author":"S Jamal","year":"2020","unstructured":"Jamal S, Khubaib M, Gangwar R, Grover S, Grover A, Hasnain SE (2020) Artificial intelligence and machine learning based prediction of resistant and susceptible mutations in Mycobacterium tuberculosis. Sci Rep 10:5487","journal-title":"Sci Rep"},{"key":"2_CR95","doi-asserted-by":"publisher","DOI":"10.1002\/9780470939932","volume-title":"Protein purification: principles, high resolution methods, and applications","author":"JC Janson","year":"2011","unstructured":"Janson JC (2011) Protein purification: principles, high resolution methods, and applications, 3rd edn. Wiley","edition":"3"},{"issue":"2","key":"2_CR96","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/j.chroma.2003.10.029","volume":"1023","author":"L Jiang","year":"2004","unstructured":"Jiang L, He L, Fountoulakis M (2004) Comparison of protein precipitation methods for sample preparation prior to proteomic analysis. J Chromatogr A 1023(2):317\u2013320","journal-title":"J Chromatogr A"},{"key":"2_CR97","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/S0076-6879(09)63022-6","volume":"463","author":"A Jungbauer","year":"2009","unstructured":"Jungbauer A, Hahn R (2009) Ion-exchange chromatography. Methods Enzymol 463:349\u2013371","journal-title":"Methods Enzymol"},{"key":"2_CR98","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.bbrc.2022.06.021","volume":"619","author":"A Kaushik","year":"2022","unstructured":"Kaushik A, Bandyopadhyay S, Porwal C, Srinivasan A, Rukmangadachar LA, Hariprasad G, Kola S, Kataria J, Singh UB (2022) 2D-DIGE based urinary proteomics and functional enrichment studies to reveal novel Mycobacterium tuberculosis and human protein biomarker candidates for pulmonary tuberculosis. Biochem Biophys Res Commun 619:15\u201321","journal-title":"Biochem Biophys Res Commun"},{"issue":"12","key":"2_CR99","doi-asserted-by":"publisher","first-page":"M111.011627","DOI":"10.1074\/mcp.M111.011627","volume":"10","author":"DS Kelkar","year":"2011","unstructured":"Kelkar DS, Kumar D, Kumar P, Balakrishnan L, Muthusamy B, Yadav AK, Shrivastava P, Marimuthu A, Anand S, Sundaram H, Kingsbury R, Harsha HC, Nair B, Prasad TS, Chauhan DS, Katoch K, Katoch VM, Kumar P, Chaerkady R, Ramachandran S, Dash D, Pandey A (2011) Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry. Mol Cell Proteomics 10(12):M111.011627","journal-title":"Mol Cell Proteomics"},{"issue":"12","key":"2_CR100","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1016\/j.tim.2004.10.005","volume":"12","author":"SL Kendall","year":"2004","unstructured":"Kendall SL, Rison SCG, Movahedzadeh F, Frita R, Stoker NG (2004) What do microarrays really tell us about Mycobacterium tuberculosis? Trends Microbiol 12(12):537\u2013544","journal-title":"Trends Microbiol"},{"key":"2_CR101","unstructured":"Kennedy RM (2001) Hydrophobic-interaction chromatography. Current protocols in protein science, Chapter 8, unit 8.4"},{"issue":"3","key":"2_CR102","first-page":"L412","volume":"322","author":"B Kestler","year":"2022","unstructured":"Kestler B, Tyler SK (2022) Latent tuberculosis testing through the ages: the search for a sleeping killer. Am J Phys Lung Cell Mol Phys 322(3):L412\u2013L419","journal-title":"Am J Phys Lung Cell Mol Phys"},{"key":"2_CR1012","doi-asserted-by":"crossref","unstructured":"Khan N, Mironov G, Berezovski MV (2016) Direct detection of endogenous microRNAs and their post-transcriptional modifications in cancer serum by capillary electrophoresis-mass spectrometry. Anal Bioanal Chem 408:2891\u20132899","DOI":"10.1007\/s00216-015-9277-y"},{"issue":"2","key":"2_CR103","first-page":"273","volume":"13","author":"M Khosrobeygi","year":"2021","unstructured":"Khosrobeygi M, Mosavari N, Salehi M, Mojgani N, Akbari M (2021) Isolation and purification of low molecular weight proteins from culture filtrate of Mycobacterium tuberculosis strain C. Iranian J Microbiol 13(2):273\u2013282","journal-title":"Iranian J Microbiol"},{"issue":"12","key":"2_CR104","doi-asserted-by":"publisher","first-page":"pdb.rot102228","DOI":"10.1101\/pdb.prot102228","volume":"2021","author":"CL Kielkopf","year":"2021","unstructured":"Kielkopf CL, Bauer W, Urbatsch IL (2021) Sodium dodecyl sulfate\u2013polyacrylamide gel electrophoresis of proteins. Cold Spring Harb Protoc 2021(12):pdb.rot102228","journal-title":"Cold Spring Harb Protoc"},{"issue":"2","key":"2_CR105","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1111\/apm.1964.60.2.241","volume":"60","author":"HK Kim","year":"1964","unstructured":"Kim HK, Magnusson M, Bentzon MW (1964) Tuberculin production: 4. Specificity of tuberculin of Mycobacterium tuberculosis and M. bovis (BCG strain). Acta Pathol Microbiol Scand 60(2):241\u2013251","journal-title":"Acta Pathol Microbiol Scand"},{"issue":"1","key":"2_CR106","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.ymeth.2011.07.010","volume":"55","author":"Y Kim","year":"2011","unstructured":"Kim Y, Babnigg G, Jedrzejczak R, Eschenfeldt WH, Li H, Maltseva N, Hatzos-Skintges C, Gu M, Makowska-Grzyska M, Wu R, An H, Chhor G, Joachimiak A (2011) High-throughput protein purification and quality assessment for crystallization. Methods 55(1):12\u201328","journal-title":"Methods"},{"key":"2_CR107","doi-asserted-by":"publisher","first-page":"3708","DOI":"10.1016\/j.csbj.2021.06.034","volume":"19","author":"ADH Kingdon","year":"2021","unstructured":"Kingdon ADH, Alderwick LJ (2021) Structure-based in silico approaches for drug discovery against Mycobacterium tuberculosis. Comput Struct Biotechnol J 19:3708\u20133719","journal-title":"Comput Struct Biotechnol J"},{"key":"2_CR1002","unstructured":"Koch R (1882) Die Aetiologie der Tuberkulose. Berl Klin Wochenschr 19:221\u2013230"},{"issue":"19","key":"2_CR108","doi-asserted-by":"publisher","DOI":"10.1172\/JCI173156","volume":"133","author":"BN Koleske","year":"2023","unstructured":"Koleske BN, Jacobs WR Jr, Bishai WR (2023) The Mycobacterium tuberculosis genome at 25 years: lessons and lingering questions. J Clin Invest 133(19):e173156","journal-title":"J Clin Invest"},{"key":"2_CR109","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2019.115731","volume":"122","author":"S K\u00f6nig","year":"2020","unstructured":"K\u00f6nig S (2020) Differential vs. comparative gel electrophoresis: new technology drives standardisation and quantification in protein two-dimensional gel electrophoresis. TrAC Trends Anal Chem 122:115731","journal-title":"TrAC Trends Anal Chem"},{"issue":"5","key":"2_CR110","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2020.165690","volume":"1866","author":"T Kowalczyk","year":"2020","unstructured":"Kowalczyk T, Ciborowski M, Kisluk J, Kretowski A, Barbas C (2020) Mass spectrometry based proteomics and metabolomics in personalized oncology. Biochim Biophys Acta (BBA) Mol Basis Dis 1866(5):165690","journal-title":"Biochim Biophys Acta (BBA) Mol Basis Dis"},{"issue":"11","key":"2_CR111","doi-asserted-by":"publisher","first-page":"e113","DOI":"10.1086\/425916","volume":"1","author":"A Kraut","year":"2004","unstructured":"Kraut A, Coodin M, Plessis R, McLean D (2004) Predictors of positive tuberculin skin test (TST) results after 2-step TST among health care workers in Manitoba, Canada. Clin Infect Dis 1(11):e113","journal-title":"Clin Infect Dis"},{"issue":"4","key":"2_CR112","doi-asserted-by":"publisher","first-page":"276","DOI":"10.5808\/GI.2014.12.4.276","volume":"12","author":"S Kumar","year":"2014","unstructured":"Kumar S, Jena L (2014) Understanding rifampicin resistance in tuberculosis through a computational approach. Genom Inform 12(4):276\u2013282","journal-title":"Genom Inform"},{"key":"2_CR113","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1007\/978-981-16-4987-5_8","volume-title":"Textbook on cloning, expression and purification of recombinant proteins","author":"R Kummari","year":"2022","unstructured":"Kummari R, Bose K (2022) Gel filtration chromatography. In: Textbook on cloning, expression and purification of recombinant proteins. Springer Nature, pp 199\u2013219"},{"issue":"4","key":"2_CR114","first-page":"335","volume":"11","author":"S Kunnath-Velayudhan","year":"2013","unstructured":"Kunnath-Velayudhan S, Porcelli SA (2013) Recent advances in defining the immunoproteome of Mycobacterium tuberculosis. Front Immunol 11(4):335","journal-title":"Front Immunol"},{"issue":"33","key":"2_CR115","doi-asserted-by":"publisher","first-page":"14703","DOI":"10.1073\/pnas.1009080107","volume":"107","author":"S Kunnath-Velayudhan","year":"2010","unstructured":"Kunnath-Velayudhan S, Salamon H, Wang HY, Davidow AL, Molina DM, Huynh VT, Cirillo DM, Michel G, Talbot EA, Perkins MD, Felgner PL, Liang X, Gennaro ML (2010) Dynamic antibody responses to the Mycobacterium tuberculosis proteome. Proc Natl Acad Sci 107(33):14703\u201314708","journal-title":"Proc Natl Acad Sci"},{"issue":"5","key":"2_CR116","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1093\/infdis\/jis421","volume":"206","author":"S Kunnath-Velayudhan","year":"2012","unstructured":"Kunnath-Velayudhan S, Davidow AL, Wang HY, Molina DM, Huynh VT, Salamon H, Pine R, Michel G, Perkins MD, Xiaowu L, Felgner PL, Flynn JL, Catanzaro A, Gennaro ML (2012) Proteome-scale antibody responses and outcome of Mycobacterium tuberculosis infection in nonhuman primates and in tuberculosis patients. J Infect Dis 206(5):697\u2013705","journal-title":"J Infect Dis"},{"issue":"13","key":"2_CR117","doi-asserted-by":"publisher","DOI":"10.1172\/JCI167762","volume":"133","author":"R Lai","year":"2023","unstructured":"Lai R, Gong DN, Williams T, Ogunsola AF, Cavallo K, Lindestam Arlehamn CS, Acolatse S, Beamer GL, Ferris MT, Sassetti CM, Lauffenburger DA, Behar SM (2023) Host genetic background is a barrier to broadly effective vaccine-mediated protection against tuberculosis. J Clin Invest 133(13):e167762","journal-title":"J Clin Invest"},{"issue":"1","key":"2_CR118","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1093\/bmb\/ldp039","volume":"93","author":"A Lalvani","year":"2010","unstructured":"Lalvani A, Pareek M (2010) A 100 year update on diagnosis of tuberculosis infection. Br Med Bull 93(1):69\u201384","journal-title":"Br Med Bull"},{"key":"2_CR119","first-page":"393","volume":"29","author":"S Landi","year":"1975","unstructured":"Landi S, Held HR, Gupta KC (1975) The multi-facets of tuberculin standardization. Dev Biol Stand 29:393\u2013411","journal-title":"Dev Biol Stand"},{"key":"2_CR1022","doi-asserted-by":"crossref","unstructured":"Lee K, O\u2019Reilly FJ (2023) Cross-linking mass spectrometry for mapping protein complex topologies in situ. Essays Biochem 67(2):215\u2013228","DOI":"10.1042\/EBC20220168"},{"issue":"4","key":"2_CR120","doi-asserted-by":"publisher","first-page":"211","DOI":"10.4167\/jbv.2006.36.4.211","volume":"36","author":"J Lee","year":"2006","unstructured":"Lee J, Paik TH, Yoo YC, Lee J, Shin A, Song CH, Jo EK, Park JK (2006) Purification of native Ag85 complex, 38-kDa and MTB12 protein antigens from the culture filtrate of Mycobacterium tuberculosis. J Bacteriol Virol 36(4):211\u2013218","journal-title":"J Bacteriol Virol"},{"issue":"12","key":"2_CR121","first-page":"288","volume":"9","author":"D Lee","year":"2024","unstructured":"Lee D, Islam MA, Natarajan S, Dudekula DB, Chung H, Park J, Oh B (2024) Identification of anti-tuberculosis drugs targeting DNA gyrase A and serine\/threonine protein kinase PknB: A machine learning-assisted drug-repurposing approach. Trop Med Infect Dis 9(12):288","journal-title":"Trop Med Infect Dis"},{"issue":"4","key":"2_CR122","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.hlife.2024.11.003","volume":"3","author":"Z Lei","year":"2025","unstructured":"Lei Z, Wang J, Liu CH (2025) Developing next-generation tuberculosis vaccines based on pathogen\u2013host interactions: towards a holistic perspective. hLife 3(4):164\u2013171","journal-title":"hLife"},{"issue":"2\u20134","key":"2_CR123","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.vetmic.2014.11.009","volume":"175","author":"FL Leite","year":"2015","unstructured":"Leite FL, Reinhardt TA, Bannantine JP, Stabel JR (2015) Envelope protein complexes of Mycobacterium avium subsp. paratuberculosis and their antigenicity. Vet Microbiol 175(2\u20134):275\u2013285","journal-title":"Vet Microbiol"},{"key":"2_CR1028","doi-asserted-by":"crossref","unstructured":"Li KK, Qu DH, Zhang HN, Chen FY, Xu L, Wang MY et al (2020) Global discovery of the PstP interactions using M. tuberculosis proteome microarray and revealing novel connections with EthR. J Proteome 215:103650. https:\/\/doi.org\/10.1016\/j.jprot.2020.103650","DOI":"10.1016\/j.jprot.2020.103650"},{"key":"2_CR124","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/156241","volume":"2015","author":"L Liljeroos","year":"2015","unstructured":"Liljeroos L, Malito E, Ferlenghi I, Bottomley MJ (2015) Structural and computational biology in the Design of Immunogenic Vaccine Antigens. J Immunol Res 2015:156241","journal-title":"J Immunol Res"},{"issue":"7","key":"2_CR125","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1038\/10890","volume":"17","author":"AJ Link","year":"1999","unstructured":"Link AJ, Eng J, Schieltz DM, Carmack E, Mize GJ, Morris DR, Garvik BM, Yates JR (1999) Direct analysis of protein complexes using mass spectrometry. Nat Biotechnol 17(7):676\u2013682","journal-title":"Nat Biotechnol"},{"key":"2_CR1021","doi-asserted-by":"crossref","unstructured":"Liu X, Salokas K, Weldatsadik RG, Gawriyski L, Varjosalo M (2020) Combined proximity labeling and affinity purificationmass spectrometry workflow for mapping and visualizing protein interaction networks. Nat Protoc 15(10):3182\u20133211. https:\/\/doi.org\/10.1038\/s41596-020-0365-x.","DOI":"10.1038\/s41596-020-0365-x"},{"issue":"6","key":"2_CR126","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1111\/jam.13323","volume":"121","author":"Y L\u00f3pez-Hern\u00e1ndez","year":"2016","unstructured":"L\u00f3pez-Hern\u00e1ndez Y, Pati\u00f1o-Rodr\u00edguez O, Garc\u00eda-Orta ST, Pinos-Rodr\u00edguez JM (2016) Mass spectrometry applied to the identification of Mycobacterium tuberculosis and biomarker discovery. J Appl Microbiol 121(6):1485\u20131497","journal-title":"J Appl Microbiol"},{"issue":"11","key":"2_CR127","first-page":"672","volume":"23","author":"X Lu","year":"2000","unstructured":"Lu X, Zhang X, Zhang Y (2000) Production, characterization and purification of monoclonal antibodies against antigens of Mycobacterium tuberculosis H37Rv strain. Zhonghua Jie He He Hu Xi Za Zhi 23(11):672\u2013675","journal-title":"Zhonghua Jie He He Hu Xi Za Zhi"},{"key":"2_CR128","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1007\/978-1-0716-1460-0_3","volume":"2314","author":"M Lucas","year":"2021","unstructured":"Lucas M, Ryan JM, Watkins J, Early K, Kruh-Garcia NA, Mehaffy C, Dobos KM (2021) Extraction and separation of Mycobacterial proteins. Methods Mol Biol 2314:77\u2013107","journal-title":"Methods Mol Biol"},{"issue":"10","key":"2_CR129","doi-asserted-by":"publisher","first-page":"2297","DOI":"10.1002\/eji.1830211002","volume":"21","author":"AR Lussow","year":"1991","unstructured":"Lussow AR, Barrios C, van Embden J, Van der Zee R, Verdini AS, Pessi A, Louis JA, Lambert PH, Del Giudice G (1991) Mycobacterial heat-shock proteins as carrier molecules. Eur J Immunol 21(10):2297\u20132302","journal-title":"Eur J Immunol"},{"issue":"1","key":"2_CR130","doi-asserted-by":"publisher","first-page":"13118","DOI":"10.1038\/s41598-025-96867-x","volume":"15","author":"D Magdalena","year":"2025","unstructured":"Magdalena D, Karol M, Bart\u0142omiej S, Konrad K (2025) Detection and accurate identification of Mycobacterium species by flow injection tandem mass spectrometry (FIA-MS\/MS) analysis of mycolic acids. Sci Rep 15(1):13118","journal-title":"Sci Rep"},{"issue":"10","key":"2_CR131","doi-asserted-by":"publisher","first-page":"1702","DOI":"10.1002\/pmic.200600853","volume":"7","author":"H M\u00e5len","year":"2007","unstructured":"M\u00e5len H, Berven FS, Fladmark KE, Wiker HG (2007) Comprehensive analysis of exported proteins from Mycobacterium tuberculosis H37Rv. Proteomics 7(10):1702\u20131718","journal-title":"Proteomics"},{"key":"2_CR132","doi-asserted-by":"crossref","unstructured":"M\u00e5len H, Pathak S, S\u00f8fteland T, de Souza GA, Wiker HG (2010) Definition of novel cell envelope associated proteins in triton X-114 extracts of Mycobacterium tuberculosis H37Rv. BMC Microbiol 29(10):132","DOI":"10.1186\/1471-2180-10-132"},{"key":"2_CR133","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2180-11-18","volume":"11","author":"H M\u00e5len","year":"2011","unstructured":"M\u00e5len H, De Souza GA, Pathak S, S\u00f8fteland T, Wiker HG (2011) Comparison of membrane proteins of Mycobacterium tuberculosis H37Rv and H37Ra strains. BMC Microbiol 11:1","journal-title":"BMC Microbiol"},{"issue":"3","key":"2_CR134","first-page":"E241","volume":"59","author":"M Martini","year":"2018","unstructured":"Martini M, Besozzi G, Barberis I (2018) The never-ending story of the fight against tuberculosis: from Koch\u2019s bacillus to global control programs. J Prev Med Hyg 59(3):E241\u2013E247","journal-title":"J Prev Med Hyg"},{"issue":"11","key":"2_CR135","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1016\/j.tim.2021.04.010","volume":"29","author":"RL Mayer","year":"2021","unstructured":"Mayer RL, Impens F (2021) Immunopeptidomics for next-generation bacterial vaccine development. Trends Microbiol 29(11):1034\u20131045","journal-title":"Trends Microbiol"},{"issue":"1","key":"2_CR136","doi-asserted-by":"publisher","first-page":"17","DOI":"10.4321\/S1575-06202009000100004","volume":"11","author":"JS Mazana","year":"2009","unstructured":"Mazana JS (2009) La tuberculosis y sus ep\u00f3nimos: Charles Mantoux (1877\u20131947). Revista Espa\u00f1ola de Sanidad Penitenciaria 11(1):17\u201323","journal-title":"Revista Espa\u00f1ola de Sanidad Penitenciaria"},{"issue":"3","key":"2_CR137","doi-asserted-by":"publisher","first-page":"190","DOI":"10.7326\/0003-4819-120-3-199402010-00003","volume":"120","author":"R Menzies","year":"1994","unstructured":"Menzies R, Vissandjee B, Rocher I, Germain Y (1994) The booster effect in two-step tuberculin testing among young adults in Montreal. Ann Intern Med 120(3):190\u2013198","journal-title":"Ann Intern Med"},{"issue":"3","key":"2_CR138","doi-asserted-by":"publisher","DOI":"10.1088\/1478-3975\/8\/3\/035003","volume":"8","author":"B M\u00e9sz\u00e1ros","year":"2011","unstructured":"M\u00e9sz\u00e1ros B, Simon I, Doszt\u00e1nyi Z (2011a) The expanding view of protein-protein interactions: complexes involving intrinsically disordered proteins. Phys Biol 8(3):035003","journal-title":"Phys Biol"},{"issue":"7","key":"2_CR139","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1002118","volume":"7","author":"B M\u00e9sz\u00e1ros","year":"2011","unstructured":"M\u00e9sz\u00e1ros B, T\u00f3th J, V\u00e9rtessy BG, Doszt\u00e1nyi Z, Simon I (2011b) Proteins with complex architecture as potential targets for drug design: a case study of Mycobacterium tuberculosis. PLoS Comput Biol 7(7):e1002118","journal-title":"PLoS Comput Biol"},{"key":"2_CR140","doi-asserted-by":"publisher","first-page":"237","DOI":"10.3389\/fgene.2015.00237","volume":"6","author":"K Meyer","year":"2015","unstructured":"Meyer K, Selbach M (2015) Quantitative affinity purification mass spectrometry: A versatile technology to study protein-protein interactions. Front Genet 6:237","journal-title":"Front Genet"},{"key":"2_CR141","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1007\/978-1-61779-821-4_24","volume":"869","author":"JS Minden","year":"2012","unstructured":"Minden JS (2012) Two-dimensional difference gel electrophoresis. Methods Mol Biol 869:287\u2013304","journal-title":"Methods Mol Biol"},{"key":"2_CR1018","doi-asserted-by":"crossref","unstructured":"Mirza SP (2012) Quantitative mass spectrometry-based approaches in cardiovascular research. Circ Cardiovasc Genet 5(4):477","DOI":"10.1161\/CIRCGENETICS.110.957753"},{"issue":"23","key":"2_CR142","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.25122","volume":"38","author":"N Mohammadnabi","year":"2024","unstructured":"Mohammadnabi N, Shamseddin J, Emadi M, Bodaghi AB, Varseh M, Shariati A, Rezaei M, Dastranj M, Farahani A (2024) Mycobacterium tuberculosis: the mechanism of pathogenicity, immune responses, and diagnostic challenges. J Clin Lab Anal 38(23):e25122","journal-title":"J Clin Lab Anal"},{"issue":"2","key":"2_CR143","first-page":"59","volume":"12","author":"N Mojgani","year":"2020","unstructured":"Mojgani N, Babaie M, Shakibamehr N, Mohammad Taheri M, Mosavari N, Ghaempanah A, Soleymani BK (2020) Purification and biological analysis of specific antigens (ESAT6\/CFP10) from Mycobacterium tuberculosis. Iran J Vet Sci Technol 12(2):59\u201367","journal-title":"Iran J Vet Sci Technol"},{"key":"2_CR144","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadva.2025.100149","volume":"7","author":"Y Montoya","year":"2025","unstructured":"Montoya Y, Deckerman P, Guler MO (2025) Protein recognition methods for diagnostics and therapy. BBA Adv 7:100149","journal-title":"BBA Adv"},{"issue":"11","key":"2_CR145","doi-asserted-by":"publisher","first-page":"2539","DOI":"10.1038\/nprot.2014.164","volume":"9","author":"JH Morris","year":"2014","unstructured":"Morris JH, Knudsen GM, Verschueren E, Johnson JR, Cimermancic P, Greninger AL, Pico AR (2014) Affinity purification-mass spectrometry and network analysis to understand protein-protein interactions. Nat Protoc 9(11):2539\u20132554","journal-title":"Nat Protoc"},{"issue":"4","key":"2_CR146","first-page":"439","volume":"75","author":"N Mosavari","year":"2021","unstructured":"Mosavari N, Karimi A, Tadayon K, Shahhosseini G, Zavaran Hosseini A, Babaie M (2021) Evaluation of heating and irradiation methods for production of purified protein derivative (PPD) of Mycobacterium tuberculosis. Arch Razi Institute 75(4):439\u2013449","journal-title":"Arch Razi Institute"},{"key":"2_CR147","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2021.643849","volume":"8","author":"G Mugumbate","year":"2021","unstructured":"Mugumbate G, Nyathi B, Zindoga A, Munyuki G (2021) Application of computational methods in understanding mutations in Mycobacterium tuberculosis drug resistance. Front Mol Biosci 8:643849","journal-title":"Front Mol Biosci"},{"issue":"7","key":"2_CR148","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1186\/1471-2334-7-84","volume":"26","author":"DJ Murphy","year":"2007","unstructured":"Murphy DJ, Brown JR (2007) Identification of gene targets against dormant phase Mycobacterium tuberculosis infections. BMC Infect Dis 26(7):84","journal-title":"BMC Infect Dis"},{"key":"2_CR149","first-page":"3060","volume":"55","author":"PJ Murphy","year":"2011","unstructured":"Murphy PJ, Stone OJ, Anderson ME (2011) Automated hydrophobic interaction chromatography column selection for use in protein purification. J Vis Exp 55:3060","journal-title":"J Vis Exp"},{"issue":"6","key":"2_CR150","doi-asserted-by":"publisher","DOI":"10.1002\/jms.4664","volume":"56","author":"KK Murray","year":"2021","unstructured":"Murray KK (2021) Lasers for matrix-assisted laser desorption ionization. J Mass Spectrom 56(6):e4664","journal-title":"J Mass Spectrom"},{"issue":"1","key":"2_CR151","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1128\/iai.59.1.372-382.1991","volume":"59","author":"S Nagai","year":"1991","unstructured":"Nagai S, Wiker HG, Harboe M, Kinomoto M (1991) Isolation and partial characterization of major protein antigens in the culture fluid of Mycobacterium tuberculosis. Infect Immun 59(1):372\u2013382","journal-title":"Infect Immun"},{"key":"2_CR1001","doi-asserted-by":"crossref","unstructured":"Nahid P, Pai M, Hopewell PC (2006) Advances in the diagnosis and treatment of tuberculosis. Proc Am Thorac Soc 3(1):103\u2013110. https:\/\/doi.org\/10.1513\/pats.200511-119JH. PMID:16493157; PMCID:PMC2658675","DOI":"10.1513\/pats.200511-119JH"},{"issue":"1","key":"2_CR152","doi-asserted-by":"publisher","first-page":"2","DOI":"10.4103\/2229-5178.93479","volume":"3","author":"S Nayak","year":"2012","unstructured":"Nayak S, Acharjya B (2012) Mantoux test and its interpretation. Indian Dermatol Online J 3(1):2\u20136","journal-title":"Indian Dermatol Online J"},{"issue":"8","key":"2_CR153","doi-asserted-by":"publisher","first-page":"2411","DOI":"10.3390\/molecules27082411","volume":"27","author":"AN Neagu","year":"2022","unstructured":"Neagu AN, Jayathirtha M, Baxter E, Donnelly M, Petre BA, Darie CC (2022) Applications of tandem mass spectrometry (MS\/MS) in protein analysis for biomedical research. Molecules 27(8):2411","journal-title":"Molecules"},{"key":"2_CR154","doi-asserted-by":"publisher","first-page":"565","DOI":"10.2116\/analsci.16.565","volume":"16","author":"PN Nesterenko","year":"2000","unstructured":"Nesterenko PN, Haddad PR (2000) Zwitterionic ion-exchangers in liquid chromatography. Anal Sci 16:565\u2013574. https:\/\/doi.org\/10.2116\/analsci.16.565","journal-title":"Anal Sci"},{"issue":"3","key":"2_CR155","first-page":"763","volume":"9","author":"TL Nguyen","year":"2024","unstructured":"Nguyen TL, Kim H (2024) Integrating immunoinformatics and computational epitope prediction for a vaccine candidate against respiratory syncytial virus. Infect Dis Model 9(3):763\u2013774","journal-title":"Infect Dis Model"},{"key":"2_CR156","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2020.116053","volume":"132","author":"Y Niu","year":"2020","unstructured":"Niu Y, Liu J, Yang R, Zhang J, Shao B (2020) Atmospheric pressure chemical ionization source as an advantageous technique for gas chromatography-tandem mass spectrometry. TrAC Trends Anal Chem 132:116053","journal-title":"TrAC Trends Anal Chem"},{"key":"2_CR157","doi-asserted-by":"publisher","DOI":"10.1016\/j.insi.2025.100012","volume":"1","author":"TA Nyijime","year":"2025","unstructured":"Nyijime TA, Shallangwa GA, Uzairu A, Umar AB, Ibrahim MT, Madkhali HA, Hamadi A, Barnawi J, Abdalla M, Ahmed AU (2025) Computational design, pharmacokinetics, molecular docking and molecular dynamic simulation of novel anti-tubercular inhibitors. In Silico Res Biomed 1:100012","journal-title":"In Silico Res Biomed"},{"key":"2_CR1006","doi-asserted-by":"crossref","unstructured":"O\u2019Connor BF, Cummins PM (2017) Hydrophobic interaction chromatography. Methods Mol Biol 1485:355\u2013363. https:\/\/doi.org\/10.1007\/978-1-4939-6412-3_18. PMID:27730562","DOI":"10.1007\/978-1-4939-6412-3_18"},{"issue":"10","key":"2_CR158","doi-asserted-by":"publisher","first-page":"1591","DOI":"10.1002\/pmic.201100509","volume":"12","author":"M Oeffinger","year":"2012","unstructured":"Oeffinger M (2012) Two steps forward\u2014one step back: advances in affinity purification mass spectrometry of macromolecular complexes. Proteomics 12(10):1591\u20131608","journal-title":"Proteomics"},{"key":"2_CR1007","doi-asserted-by":"crossref","unstructured":"\u00d3\u2019F\u00e1g\u00e1in C, Cummins PM, O\u2019Connor BF (2017) Gel-filtration chromatography. Methods Mol Biol 1485:15\u201325. https:\/\/doi.org\/10.1007\/978-1-4939-6412-3_2. PMID:27730546; PMCID:PMC7121854","DOI":"10.1007\/978-1-4939-6412-3_2"},{"issue":"9","key":"2_CR159","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1080\/14760584.2020.1825950","volume":"19","author":"D Ortega-Tirado","year":"2020","unstructured":"Ortega-Tirado D, Arvizu-Flores AA, Velazquez C, Garibay-Escobar A (2020) The role of immunoinformatics in the development of T-cell peptide-based vaccines against Mycobacterium tuberculosis. Expert Rev Vaccines 19(9):831\u2013841","journal-title":"Expert Rev Vaccines"},{"issue":"14","key":"2_CR160","doi-asserted-by":"publisher","first-page":"4146","DOI":"10.1111\/febs.16369","volume":"289","author":"R Pal","year":"2022","unstructured":"Pal R, Bisht MK, Mukhopadhyay S (2022) Secretory proteins of Mycobacterium tuberculosis and their roles in modulation of host immune responses: focus on therapeutic targets. FEBS J 289(14):4146\u20134171","journal-title":"FEBS J"},{"issue":"3","key":"2_CR161","doi-asserted-by":"publisher","first-page":"279","DOI":"10.3390\/diagnostics15030279","volume":"15","author":"G Paredes-Gutierrez","year":"2025","unstructured":"Paredes-Gutierrez G, Perea-Jacobo R, Acosta-Mesa HG, Mezura-Montes E, Morales Reyes JL, Zenteno-Cuevas R, Guerrero-Chevannier M\u00c1, Mu\u00f1iz-Salazar R, Flores DL (2025) Predicting drug resistance in Mycobacterium tuberculosis: A machine learning approach to genomic mutation analysis. Diagnostics 15(3):279","journal-title":"Diagnostics"},{"key":"2_CR162","volume-title":"Mycobacterium tuberculosis protocols","year":"2008","unstructured":"Parish T, Stoker NG (eds) (2008) Mycobacterium tuberculosis protocols. Springer"},{"key":"2_CR163","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1039\/a808477g","volume":"36","author":"JM Patil","year":"1999","unstructured":"Patil JM, Okada T (1999) Anion-modulated switching of retention properties of a zwitterionic stationary phase. Anal Commun 36:9\u201311","journal-title":"Anal Commun"},{"key":"2_CR164","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1186\/s12916-016-0575-9","volume":"14","author":"J Phelan","year":"2016","unstructured":"Phelan J, Coll F, McNerney R, Ascher DB, Pires DE, Furnham N, Coeck N, Hill-Cawthorne GA, Nair MB, Mallard K, Ramsay A, Campino S, Hibberd ML, Pain A, Rigouts L, Clark TG (2016) Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance. BMC Med 14:31","journal-title":"BMC Med"},{"key":"2_CR165","doi-asserted-by":"crossref","unstructured":"Phillips AT (1995) Desalting, concentration, and buffer exchange by dialysis and ultrafiltration. In: Current protocols in protein science. First published December 1995","DOI":"10.1002\/0471140864.ps0404s02"},{"key":"2_CR167","doi-asserted-by":"publisher","first-page":"19848","DOI":"10.1038\/srep19848","volume":"6","author":"DEV Pires","year":"2016","unstructured":"Pires DEV, Chen J, Blundell TL, Ascher DB (2016) In silico functional dissection of saturation mutagenesis: interpreting the relationship between phenotypes and changes in protein stability, interactions and activity. Sci Rep 6:19848","journal-title":"Sci Rep"},{"issue":"5","key":"2_CR168","doi-asserted-by":"publisher","first-page":"403","DOI":"10.5588\/ijtld.21.0055","volume":"25","author":"NR Pollock","year":"2021","unstructured":"Pollock NR, MacIntyre AT, Blauwkamp TA, Blair L, Ho C, Calderon R, Franke MF (2021) Detection of Mycobacterium tuberculosis cell-free DNA to diagnose TB in pediatric and adult patients. Int J Tuberc Lung Dis 25(5):403","journal-title":"Int J Tuberc Lung Dis"},{"issue":"4676","key":"2_CR169","doi-asserted-by":"publisher","first-page":"1657","DOI":"10.1038\/1831657a0","volume":"183","author":"J Porath","year":"1959","unstructured":"Porath J, Flodin P (1959) Gel filtration: A method for desalting and group separation. Nature 183(4676):1657\u20131659","journal-title":"Nature"},{"key":"2_CR170","doi-asserted-by":"publisher","first-page":"427","DOI":"10.3389\/fmicb.2016.00427","volume":"7","author":"MG Potgieter","year":"2016","unstructured":"Potgieter MG, Nakedi KC, Ambler JM, Nel AJ, Garnett S, Soares NC, Mulder N, Blackburn JM (2016) Proteogenomic analysis of Mycobacterium smegmatis using high resolution mass spectrometry. Front Microbiol 7:427","journal-title":"Front Microbiol"},{"key":"2_CR171","doi-asserted-by":"publisher","first-page":"1142656","DOI":"10.3389\/fmolb.2023.1142656","volume":"10","author":"CP Ptak","year":"2023","unstructured":"Ptak CP, Hsieh CL, Garnett JA, Rappuoli R, Lin YP (2023) Editorial: intersection of biophysical and structural approaches in vaccine design. Front Mol Biosci 10:1142656","journal-title":"Front Mol Biosci"},{"issue":"3","key":"2_CR172","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1046\/j.1365-2958.2002.03237.x","volume":"46","author":"AS Pym","year":"2002","unstructured":"Pym AS, Brodin P, Brosch R, Huerre M, Cole ST (2002) Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti. Mol Microbiol 46(3):709\u2013717","journal-title":"Mol Microbiol"},{"issue":"10","key":"2_CR173","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0276085","volume":"17","author":"MA Rahman","year":"2022","unstructured":"Rahman MA, Heme UH, Parvez MAK (2022) In silico functional annotation of hypothetical proteins from the bacillus paralicheniformis strain Bac84 reveals proteins with biotechnological potentials and adaptational functions to extreme environments. PLoS One 17(10):e0276085","journal-title":"PLoS One"},{"issue":"Suppl 2","key":"2_CR174","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1002\/pmic.200600553","volume":"6","author":"V Reisinger","year":"2006","unstructured":"Reisinger V, Eichacker LA (2006) Analysis of membrane protein complexes by blue native PAGE. Proteomics 6(Suppl 2):6\u201315","journal-title":"Proteomics"},{"key":"2_CR175","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1007\/978-1-60327-064-9_33","volume":"424","author":"V Reisinger","year":"2008","unstructured":"Reisinger V, Eichacker LA (2008) Isolation of membrane protein complexes by blue native electrophoresis. Methods Mol Biol 424:423\u2013431","journal-title":"Methods Mol Biol"},{"issue":"5","key":"2_CR176","first-page":"16","volume":"20","author":"F Reyes","year":"2013","unstructured":"Reyes F, Otero O, Camacho F, Sarmiento ME, Acosta A, Guill\u00e9n G (2013) Purification of an IgA monoclonal antibody specific for the Acr protein of Mycobacterium tuberculosis by immunoaffinity chromatography. Malaysian J Med Sci 20(5):16\u201322","journal-title":"Malaysian J Med Sci"},{"key":"2_CR177","doi-asserted-by":"publisher","first-page":"16274","DOI":"10.1038\/nmicrobiol.2016.274","volume":"2","author":"JM Rock","year":"2017","unstructured":"Rock JM, Hopkins FF, Chavez A, Diallo M, Chase MR, Gerrick ER, Pritchard JR, Church GM, Rubin EJ, Sassetti CM, Schnappinger D, Fortune SM (2017) Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform. Nat Microbiol 2:16274","journal-title":"Nat Microbiol"},{"issue":"11","key":"2_CR178","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1007\/BF02602749","volume":"10","author":"DN Rose","year":"1995","unstructured":"Rose DN, Schechter CB, Adler JJ (1995) Interpretation of the tuberculin skin test. J Gen Intern Med 10(11):635\u2013642","journal-title":"J Gen Intern Med"},{"issue":"5","key":"2_CR179","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1002\/(SICI)1522-2683(20000301)21:5<935::AID-ELPS935>3.0.CO;2-P","volume":"21","author":"I Rosenkrands","year":"2000","unstructured":"Rosenkrands I, Weldingh K, Jacobsen S, Hansen CV, Florio W, Gianetri I, Andersen P (2000) Mapping and identification of Mycobacterium tuberculosis proteins by two-dimensional gel electrophoresis, microsequencing and immunodetection. Electrophoresis 21(5):935\u2013948","journal-title":"Electrophoresis"},{"key":"2_CR1038","doi-asserted-by":"crossref","unstructured":"Rusic D, Kumric M, Seselja Perisin A, Leskur D, Bukic J, Modun D et al (2024) Tackling the antimicrobial resistance \u201cpandemic\u201d with machine learning tools: a summary of available evidence. Microorganisms 12(5):842","DOI":"10.3390\/microorganisms12050842"},{"key":"2_CR180","doi-asserted-by":"crossref","unstructured":"Ryan JM, Dobos KM, Kruh-Garcia NA (2022) Mycobacterium tuberculosis extracellular vesicle enrichment through size exclusion chromatography. J Vis Exp 183","DOI":"10.3791\/63895-v"},{"key":"2_CR181","doi-asserted-by":"crossref","unstructured":"Safarian S, Opel-Reading HK, Wu D, Mehdipour AR, Hards K, Harold LK, Radloff M, Stewart I, Welsch S, Hummer G, Cook GM, Krause KL, Michel H (2021) The cryo-EM structure of the bd oxidase from M. Tuberculosis reveals a unique structural framework and enables rational drug design to combat TB. Nature Commun 12:5236","DOI":"10.1038\/s41467-021-25537-z"},{"issue":"2","key":"2_CR182","doi-asserted-by":"publisher","DOI":"10.5808\/gi.23001","volume":"21","author":"AS Saikat","year":"2023","unstructured":"Saikat AS (2023) Computational approaches for molecular characterization and structure-based functional elucidation of a hypothetical protein from Mycobacterium tuberculosis. Genom Informat 21(2):e25","journal-title":"Genom Informat"},{"key":"2_CR183","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.aca.2017.02.023","volume":"965","author":"M Sajid","year":"2017","unstructured":"Sajid M (2017) Porous membrane protected micro-solid-phase extraction: A review of features, advancements and applications. Anal Chim Acta 965:36\u201353","journal-title":"Anal Chim Acta"},{"issue":"10","key":"2_CR184","volume":"9","author":"Z Sajid","year":"2024","unstructured":"Sajid Z, Akhtar T, Ahmad K, Haroon M (2024) Molecular docking simulation and ADMET\/pharmacokinetic screening of newly designed 2-(2-(aryl)-4-oxo-4,5-dihydrothiazol-5-yl)acetohydrazides as potential antitubercular agents. Chemist Select 9(10):e202400000","journal-title":"Chemist Select"},{"issue":"2","key":"2_CR185","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000002","volume":"6","author":"A Sandgren","year":"2009","unstructured":"Sandgren A, Strong M, Muthukrishnan P, Weiner BK, Church GM, Murray MB (2009) Tuberculosis drug resistance mutation database. PLoS Med 6(2):e2","journal-title":"PLoS Med"},{"key":"2_CR186","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/312709","volume":"2013","author":"M Saraswat","year":"2013","unstructured":"Saraswat M, Musante L, Ravid\u00e1 A, Shortt B, Byrne B, Holthofer H (2013) Preparative purification of recombinant proteins: current status and future trends. Biomed Res Int 2013:312709","journal-title":"Biomed Res Int"},{"key":"2_CR187","first-page":"120","volume":"5","author":"E Saridakis","year":"2022","unstructured":"Saridakis E, Vishwakarma R, Lai-Kee-Him J, Martin K, Simon I, Cohen-Gonsaud M, Coste F, Bron P, Margeat E, Boudvillain M (2022) Cryo-EM structure of transcription termination factor Rho from Mycobacterium tuberculosis reveals bicyclomycin resistance mechanism. Communicat Biol 5:120","journal-title":"Communicat Biol"},{"issue":"1","key":"2_CR188","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1074\/mcp.M300074-MCP200","volume":"3","author":"F Schmidt","year":"2004","unstructured":"Schmidt F, Donahoe S, Hagens K, Mattow J, Schaible UE, Kaufmann SH, Aebersold R, Jungblut PR (2004) Complementary analysis of the Mycobacterium tuberculosis proteome by two-dimensional electrophoresis and isotope-coded affinity tag technology. Mol Cell Proteomics 3(1):24\u201342","journal-title":"Mol Cell Proteomics"},{"issue":"9","key":"2_CR189","doi-asserted-by":"publisher","first-page":"2095","DOI":"10.3390\/polym12092095","volume":"12","author":"T Schuett","year":"2020","unstructured":"Schuett T, Kimmig J, Zechel S, Schubert US (2020) Automated polymer purification using dialysis. Polymers 12(9):2095","journal-title":"Polymers"},{"key":"2_CR1011","doi-asserted-by":"crossref","unstructured":"Schuhmacher M, Glocker MO, Wunderlin M, Przybylski M (1996) Direct isolation of proteins from sodium dodecyl sulfatepolyacrylamide gel electrophoresis and analysis by electrospray-ionization mass spectrometry. Electrophoresis 17(5):848\u2013854","DOI":"10.1002\/elps.1150170506"},{"key":"2_CR190","volume-title":"Protein purification: principles and practice","author":"RK Scopes","year":"1993","unstructured":"Scopes RK (1993) Protein purification: principles and practice, 3rd edn. Springer Science & Business Media","edition":"3"},{"issue":"4","key":"2_CR191","first-page":"225","volume":"44","author":"KS Senthil Kumar","year":"2002","unstructured":"Senthil Kumar KS, Uma Devi KR, Alamelu R (2002) Isolation and evaluation of diagnostic value of two major secreted proteins of Mycobacterium tuberculosis. Indian J Chest Dis Allied Sci 44(4):225\u2013232","journal-title":"Indian J Chest Dis Allied Sci"},{"issue":"4","key":"2_CR192","doi-asserted-by":"publisher","first-page":"2006","DOI":"10.1021\/acs.jproteome.4c01040","volume":"24","author":"LR Serrano","year":"2025","unstructured":"Serrano LR, Pelin A, Arrey TN, Damoc NE, Richards AL, Zhou Y, Lancaster NM, Peters-Clarke TM, Pashkova A, Jang GM, Eckhardt M, Quarmby ST, Zeller M, Hermanson D, Stewart H, Hock C, Makarov A, Zabrouskov V, Krogan NJ, Coon JJ, Swaney DL (2025) Affinity purification mass spectrometry on the Orbitrap\u2013Astral mass spectrometer enables high-throughput protein\u2013protein interaction mapping. J Proteome Res 24(4):2006\u20132016","journal-title":"J Proteome Res"},{"key":"2_CR1005","unstructured":"Shaik A (2020) Ion exchange chromatography, 1st edn. Springer, Singapore"},{"key":"2_CR193","doi-asserted-by":"publisher","DOI":"10.1016\/j.jctube.2021.100256","volume":"24","author":"GA Shallangwa","year":"2021","unstructured":"Shallangwa GA, Adeniji SE (2021) Binding profile of protein\u2013ligand inhibitor complex and structure based design of new potent compounds via computer-aided virtual screening. J Clin Tubercul Other Mycobacter Dis 24:100256","journal-title":"J Clin Tubercul Other Mycobacter Dis"},{"issue":"6","key":"2_CR194","doi-asserted-by":"publisher","first-page":"1752","DOI":"10.1016\/j.ekir.2024.03.010","volume":"9","author":"S Sharma","year":"2024","unstructured":"Sharma S, Shamy OE, Wilmington A, Keller B, Aslam N, Tran H, Rutherford P, Uribarri J (2024) Performance evaluation of an automated peritoneal dialysis solution generation system in patients using automated peritoneal dialysis. Kidney Intl Reports 9(6):1752\u20131757","journal-title":"Kidney Intl Reports"},{"issue":"8","key":"2_CR195","doi-asserted-by":"publisher","first-page":"2053","DOI":"10.1007\/s00216-018-0899-8","volume":"410","author":"PS Shen","year":"2018","unstructured":"Shen PS (2018) The 2017 Nobel prize in chemistry: Cryo-EM comes of age. Anal Bioanal Chem 410(8):2053\u20132057","journal-title":"Anal Bioanal Chem"},{"key":"2_CR196","doi-asserted-by":"publisher","first-page":"2423","DOI":"10.1016\/j.csbj.2021.04.034","volume":"19","author":"P Singh","year":"2021","unstructured":"Singh P, Jamal S, Ahmed F, Saqib N, Mehra S, Ali W, Roy D, Ehtesham NZ, Hasnain SE (2021) Computational modeling and bioinformatic analyses of functional mutations in drug target genes in Mycobacterium tuberculosis. Comput Struct Biotechnol J 19:2423\u20132446","journal-title":"Comput Struct Biotechnol J"},{"issue":"1","key":"2_CR197","doi-asserted-by":"publisher","first-page":"26116","DOI":"10.1038\/s41598-024-77442-2","volume":"14","author":"N Singpanomchai","year":"2024","unstructured":"Singpanomchai N, Ratthawongjirakul P (2024) The CRISPR-dCas9 interference system suppresses inhA gene expression in Mycobacterium smegmatis. Sci Rep 14(1):26116","journal-title":"Sci Rep"},{"key":"2_CR198","unstructured":"Sirri N, Guyeux C, Sola C (2021) Advanced machine learning for predicting drug resistance in clinical isolates of Mycobacterium tuberculosis complex World Conference on Complex Systems, 2021"},{"key":"2_CR1032","doi-asserted-by":"crossref","unstructured":"\u015aled\u017a P, Caflisch A (2018) Protein structure-based drug design: from docking to molecular dynamics. Curr Opin Struct Biol 48:93\u2013102. https:\/\/doi.org\/10.1016\/j.sbi.2017.10.010. PMID:29149726","DOI":"10.1016\/j.sbi.2017.10.010"},{"issue":"4","key":"2_CR199","first-page":"1116","volume":"17","author":"HA Sober","year":"1958","unstructured":"Sober HA, Peterson EA (1958) Protein chromatography on ion exchange cellulose. Fed Proc 17(4):1116\u20131126","journal-title":"Fed Proc"},{"issue":"2","key":"2_CR200","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.mimet.2009.01.023","volume":"77","author":"SH Song","year":"2009","unstructured":"Song SH, Park KU, Lee JH, Kim EC, Kim JQ, Song J (2009) Electrospray ionization-tandem mass spectrometry analysis of the mycolic acid profiles for the identification of common clinical isolates of mycobacterial species. J Microbiol Methods 77(2):165\u2013177","journal-title":"J Microbiol Methods"},{"issue":"4 Suppl 1","key":"2_CR201","doi-asserted-by":"publisher","first-page":"S277","DOI":"10.1074\/mcp.M116.065953","volume":"16","author":"L Song","year":"2017","unstructured":"Song L, Wallstrom G, Yu X, Hopper M, Van Duine J, Steel J, Park J, Wiktor P, Kahn P, Brunner A, Wilson D, Jenny-Avital ER, Qiu J, Labaer J, Magee DM, Achkar JM (2017) Identification of antibody targets for tuberculosis serology using high-density nucleic acid programmable protein arrays. Mol Cell Proteomics 16(4 Suppl 1):S277\u2013S289","journal-title":"Mol Cell Proteomics"},{"issue":"5","key":"2_CR202","doi-asserted-by":"publisher","first-page":"1710","DOI":"10.1128\/iai.63.5.1710-1717.1995","volume":"63","author":"AL S\u00f8rensen","year":"1995","unstructured":"S\u00f8rensen AL, Nagai S, Houen G, Andersen P, Andersen AB (1995) Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis. Infect Immun 63(5):1710\u20131717","journal-title":"Infect Immun"},{"key":"2_CR203","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2023.125022","volume":"243","author":"S Sreelatha","year":"2023","unstructured":"Sreelatha S, Nagarajan U, Natarajan S (2023) Protein targets in Mycobacterium tuberculosis and their inhibitors for therapeutic implications: A narrative review. Int J Biol Macromol 243:125022","journal-title":"Int J Biol Macromol"},{"issue":"1\u20132","key":"2_CR204","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/S0021-9673(00)00999-7","volume":"908","author":"A Staby","year":"2001","unstructured":"Staby A, Jensen RH, Bensch M, Hubbuch J, D\u00fcnweber DL, Krarup J, Nielsen J, Lund M, Kidal S, Hansen TB, Jensen IH (2001) Comparison of chromatographic ion-exchange resins: II. More strong anion-exchange resins. J Chromatogr A 908(1\u20132):149\u2013161","journal-title":"J Chromatogr A"},{"issue":"1","key":"2_CR205","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.chroma.2004.11.094","volume":"1069","author":"A Staby","year":"2005","unstructured":"Staby A, Jensen IH, Sand MB, Hansen RG, Jacobsen JH, Andersen LA, Gerstenberg M, Bruus UK, Krarup J, Nielsen J, Lund M, Kidal S, Hansen TB (2005) Comparison of chromatographic ion-exchange resins: IV. Strong and weak cation-exchange resins and heparin resins. J Chromatogr A 1069(1):65\u201377","journal-title":"J Chromatogr A"},{"issue":"1\u20132","key":"2_CR206","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.chroma.2007.06.048","volume":"1164","author":"A Staby","year":"2007","unstructured":"Staby A, Jensen IH, Sand MB, Hansen RG, Jacobsen JH, Andersen LA, Gerstenberg M, Bruus UK, Krarup J, Nielsen J, Lund M, Kidal S, Hansen TB (2007) Comparison of chromatographic ion-exchange resins: VI. Weak anion-exchange resins. J Chromatogr A 1164(1\u20132):82\u201394","journal-title":"J Chromatogr A"},{"issue":"3","key":"2_CR207","doi-asserted-by":"publisher","first-page":"e00354","DOI":"10.1128\/mSphere.00354-19","volume":"4","author":"CE Stamm","year":"2019","unstructured":"Stamm CE, Pasko BL, Chaisavaneeyakorn S, Franco LH, Nair VR, Weigele BA, Alto NM, Shiloh MU (2019) Screening Mycobacterium tuberculosis secreted proteins identifies Mpt64 as a eukaryotic membrane-binding bacterial effector. mSphere 4(3):e00354\u2013e00319","journal-title":"mSphere"},{"issue":"12","key":"2_CR208","doi-asserted-by":"publisher","first-page":"3704","DOI":"10.1002\/pmic.200401048","volume":"4","author":"T Stasyk","year":"2004","unstructured":"Stasyk T, Huber LA (2004) Zooming in: fractionation strategies in proteomics. Proteomics 4(12):3704\u20133716","journal-title":"Proteomics"},{"key":"2_CR1026","doi-asserted-by":"crossref","unstructured":"Stoevesandt O, Taussig MJ, He M (2009) Protein microarrays: high-throughput tools for proteomics. Expert Rev Proteomics 6(2):145\u2013157. https:\/\/doi.org\/10.1586\/epr.09.2. PMID:19385942; PMCID:PMC7105755","DOI":"10.1586\/epr.09.2"},{"key":"2_CR209","doi-asserted-by":"publisher","first-page":"12685","DOI":"10.1038\/s41598-023-39436-4","volume":"13","author":"DNS Suameitria Dewi","year":"2023","unstructured":"Suameitria Dewi DNS, Mertaniasih NM, Soedarsono, Hagino K, Yamazaki T, Ozeki Y, Artama WT, Kobayashi H, Inouchi E, Yoshida Y, Ishikawa S, Shaban AK, Tateishi Y, Nishiyama A, Ato M, Matsumoto S (2023) Antibodies against native proteins of Mycobacterium tuberculosis can detect pulmonary tuberculosis patients. Sci Rep 13:12685","journal-title":"Sci Rep"},{"issue":"7","key":"2_CR210","doi-asserted-by":"publisher","first-page":"4448","DOI":"10.21037\/jtd-21-913","volume":"13","author":"B Sun","year":"2021","unstructured":"Sun B, Sun Y (2021) Diagnostic performance of DNA microarray for detecting rifampicin and isoniazid resistance in Mycobacterium tuberculosis. J Thorac Dis 13(7):4448\u20134454","journal-title":"J Thorac Dis"},{"key":"2_CR211","doi-asserted-by":"publisher","first-page":"16064","DOI":"10.1038\/ncomms16064","volume":"8","author":"S Sun","year":"2017","unstructured":"Sun S, Li L, Yang F, Wang X, Fan F, Yang M, Chen C, Li X, Wang HW, Sui SF (2017) Cryo-EM structures of the ATP-bound Vps4E233Q hexamer and its complex with Vta1 at near-atomic resolution. Nat Commun 8:16064","journal-title":"Nat Commun"},{"key":"2_CR212","doi-asserted-by":"crossref","unstructured":"Sun MR, Xing JY, Li XT, Fang R, Zhang Y, Li ZL, Song NN (2025) Recent advances in research on Mycobacterium tuberculosis virulence factors and their role in pathogenesis. J Microbiol Immunol Infect","DOI":"10.1016\/j.jmii.2025.03.017"},{"issue":"7","key":"2_CR213","doi-asserted-by":"publisher","first-page":"2101","DOI":"10.1021\/ac069383v","volume":"78","author":"F Svec","year":"2006","unstructured":"Svec F, Huber CG (2006 Apr 1) (2006). Monolithic materials: promises, challenges, achievements. Anal Chem 78(7):2101\u20132107","journal-title":"Anal Chem"},{"issue":"6","key":"2_CR214","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1074\/mcp.R120.001936","volume":"19","author":"GD Syu","year":"2020","unstructured":"Syu GD, Dunn J, Zhu H (2020) Developments and applications of functional protein microarrays. Mol Cell Proteomics 19(6):916\u2013927","journal-title":"Mol Cell Proteomics"},{"key":"2_CR1023","doi-asserted-by":"crossref","unstructured":"Szewczyk R, Kowalski K, Janiszewska-Drobinska B, Druszczy\u0144ska M (2013) Rapid method for mycobacterium tuberculosis identification using electrospray ionization tandem mass spectrometry analysis of mycolic acids. Diagn Microbiol Infect Dis 76(3):298\u2013305. https:\/\/doi.org\/10.1016\/j.diagmicrobio.2013.03.025","DOI":"10.1016\/j.diagmicrobio.2013.03.025"},{"issue":"2","key":"2_CR215","doi-asserted-by":"publisher","DOI":"10.1002\/smmd.70007","volume":"4","author":"N Temur","year":"2025","unstructured":"Temur N, Eren EE, Celik I, Y\u0131ld\u0131z IE, Nisari M, Unal IS, Celik C, Ildiz N, Ocsoy I (2025) The recent development in the diagnosis of Mycobacterium tuberculosis. Smart Med 4(2):e70007","journal-title":"Smart Med"},{"key":"2_CR3001","doi-asserted-by":"crossref","unstructured":"Thakur KG, Praveena T, Gopal B (2010) Structural and biochemical bases for the redox sensitivity of Mycobacterium tuberculosis RslA. J Mol Biol 397(5):1199-208. https:\/\/doi.org\/10.1016\/j.jmb.2010.02.026. Epub 2010 Feb 22. PMID: 20184899; PMCID: PMC2877774","DOI":"10.1016\/j.jmb.2010.02.026"},{"issue":"4","key":"2_CR216","first-page":"587","volume":"119","author":"NJ Thompson","year":"1979","unstructured":"Thompson NJ, Glassroth JL, Snider DE Jr, Farer LS (1979) The booster phenomenon in serial tuberculin testing. Am Rev Respir Dis 119(4):587\u2013597","journal-title":"Am Rev Respir Dis"},{"issue":"1","key":"2_CR217","doi-asserted-by":"publisher","first-page":"10","DOI":"10.14712\/fb2014060010010","volume":"60","author":"D Tiwari","year":"2014","unstructured":"Tiwari D, Tiwari RP, Chandra R, Bisen PS, Haque S (2014) Efficient ELISA for diagnosis of active tuberculosis employing a cocktail of secretory proteins of Mycobacterium tuberculosis. Folia Biol 60(1):10\u201320","journal-title":"Folia Biol"},{"key":"2_CR218","doi-asserted-by":"crossref","unstructured":"Trauger SA, Webb W, Siuzdak G (2002) Peptide and protein analysis with mass spectrometry. J Spectrosc 16:15\u201328","DOI":"10.1155\/2002\/320152"},{"issue":"1","key":"2_CR219","first-page":"28","volume":"4","author":"PQ Truong","year":"2014","unstructured":"Truong PQ, Hammer E, Salazar MG, Ha DT, Huong NL, Hieu DM, Hoa NT, Thuy PT, Volker U (2014) 2D DIGE proteomic analysis of multidrug resistant and susceptible clinical Mycobacterium tuberculosis isolates. J Integrat Omics 4(1):28\u201336","journal-title":"J Integrat Omics"},{"issue":"1","key":"2_CR220","doi-asserted-by":"publisher","first-page":"113","DOI":"10.4103\/bbrj.bbrj_39_25","volume":"9","author":"L Udhayabanu","year":"2025","unstructured":"Udhayabanu L, Sridharan KS, Antony T (2025) Pitfalls in using matrix-assisted laser desorption ionization-time of flight mass spectrometry for the identification of Mycobacterium. Biomed Biotechnol Res J (BBRJ) 9(1):113\u2013117","journal-title":"Biomed Biotechnol Res J (BBRJ)"},{"key":"2_CR1020","doi-asserted-by":"crossref","unstructured":"van Bentum M, Selbach M (2021) An introduction to advanced targeted acquisition methods. Mol Cell Proteomics 20:100165","DOI":"10.1016\/j.mcpro.2021.100165"},{"issue":"4","key":"2_CR221","doi-asserted-by":"publisher","first-page":"410","DOI":"10.4103\/ijmy.ijmy_212_24","volume":"13","author":"AA Velayati","year":"2024","unstructured":"Velayati AA, Mitaria S, Farnia P, Farnia P, Ghanavi J, Maleknia M, Murase Y, Hoffner S (2024) Exploring the genetic landscape of Mycobacterium tuberculosis: unlocking the differences between latent and active tuberculosis. Intl J Mycobacteriol 13(4):410\u2013419","journal-title":"Intl J Mycobacteriol"},{"key":"2_CR1035","doi-asserted-by":"crossref","unstructured":"Vieira TF, Martins FG, Moreira JP, Barbosa T, Sousa SF (2021) In silico identification of possible inhibitors for protein kinase B (PknB) of mycobacterium tuberculosis. Molecules 26(20):6162","DOI":"10.3390\/molecules26206162"},{"issue":"3","key":"2_CR222","doi-asserted-by":"publisher","first-page":"1351","DOI":"10.1038\/nprot.2006.234","volume":"1","author":"S Viswanathan","year":"2006","unstructured":"Viswanathan S, Unl\u00fc M, Minden JS (2006) Two-dimensional difference gel electrophoresis. Nat Protoc 1(3):1351\u20131358","journal-title":"Nat Protoc"},{"issue":"1","key":"2_CR223","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4103\/0250-474X.102537","volume":"74","author":"VK Vyas","year":"2012","unstructured":"Vyas VK, Ukawala RD, Ghate M, Chintha C (2012) Homology modeling a fast tool for drug discovery: current perspectives. Indian J Pharm Sci 74(1):1\u201317","journal-title":"Indian J Pharm Sci"},{"issue":"1","key":"2_CR224","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1084\/jem.33.1.119","volume":"33","author":"AB Wadsworth","year":"1921","unstructured":"Wadsworth AB, Maltaner F (1921 Jan 1) (1921). Purification and concentration of antigens for complement fixation by methods of dialysis, adsorption, and extraction. J Exp Med 33(1):119\u2013123","journal-title":"J Exp Med"},{"key":"2_CR225","first-page":"359","volume":"9","author":"NW Wang","year":"1990","unstructured":"Wang NW (1990) Ion exchange in purification. Bioprocess Technol 9:359\u2013400","journal-title":"Bioprocess Technol"},{"issue":"8","key":"2_CR226","doi-asserted-by":"publisher","first-page":"1118","DOI":"10.1101\/gr.3994105","volume":"15","author":"R Wang","year":"2005","unstructured":"Wang R, Prince JT, Marcotte EM (2005) Mass spectrometry of the M. Smegmatis proteome: protein expression levels correlate with function, operons, and codon bias. Genome Res 15(8):1118\u20131126","journal-title":"Genome Res"},{"key":"2_CR228","doi-asserted-by":"publisher","first-page":"15615","DOI":"10.1038\/srep15615","volume":"5","author":"C Wang","year":"2015","unstructured":"Wang C, Wei LL, Shi LY, Pan ZF, Yu XM, Li TY, Liu CM, Ping ZP, Jiang TT, Chen ZL, Mao LG, Li ZJ, Li JC (2015) Screening and identification of five serum proteins as novel potential biomarkers for cured pulmonary tuberculosis. Sci Rep 5:15615","journal-title":"Sci Rep"},{"issue":"37","key":"2_CR229","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2403421121","volume":"121","author":"Y Wang","year":"2024","unstructured":"Wang Y, Gao S, Wu F, Gong Y, Mu N, Wei C, Wu C, Wang J, Yan N, Yang H, Zhang Y, Liu J, Wang Z, Yang X, Lam SM, Shui G, Li S, Da L, Guddat LW, Rao Z, Zhang L (2024) Cryo-EM structures of a mycobacterial ABC transporter that mediates rifampicin resistance. Proc Natl Acad Sci 121(37):e2403421121","journal-title":"Proc Natl Acad Sci"},{"issue":"8","key":"2_CR230","doi-asserted-by":"publisher","first-page":"3492","DOI":"10.1128\/IAI.66.8.3492-3500.1998","volume":"66","author":"K Weldingh","year":"1998","unstructured":"Weldingh K, Rosenkrands I, Jacobsen S, Rasmussen PB, Elhay MJ, Andersen P (1998) Two-dimensional electrophoresis for analysis of Mycobacterium tuberculosis culture filtrate and purification and characterization of six novel proteins. Infect Immun 66(8):3492\u20133500","journal-title":"Infect Immun"},{"key":"2_CR3002","doi-asserted-by":"crossref","unstructured":"Weldingh K, Hansen A, Jacobsen S, Andersen P (2000) High resolution electroelution of polyacrylamide gels for the purification of single proteins from mycobacterium tuberculosis culture filtrate. Scand J Immunol 51(1):79\u201386","DOI":"10.1046\/j.1365-3083.2000.00655.x"},{"key":"2_CR231","first-page":"531","volume":"112","author":"MR Wilkins","year":"1999","unstructured":"Wilkins MR, Gasteiger E, Bairoch A, Sanchez JC, Williams KL, Appel RD, Hochstrasser DF (1999) Protein identification and analysis tools in the ExPASy server. Methods Mol Biol 112:531\u2013552","journal-title":"Methods Mol Biol"},{"key":"2_CR232","first-page":"A.3F.1\u2013A.3F.8","volume":"13","author":"P Wingfield","year":"2001","unstructured":"Wingfield P (2001) Protein precipitation using ammonium sulfate. Curr Protoc Protein Sci 13:A.3F.1\u2013A.3F.8","journal-title":"Curr Protoc Protein Sci"},{"key":"2_CR1027","doi-asserted-by":"crossref","unstructured":"Wolf-Yadlin A, Sevecka M, MacBeath G (2009) Dissecting protein function and signaling using protein microarrays. Curr Opin Chem Biol 13(4):398\u2013405. https:\/\/doi.org\/10.1016\/j.cbpa.2009.06.027. PMID:19660979; PMCID:PMC2811369","DOI":"10.1016\/j.cbpa.2009.06.027"},{"key":"2_CR234","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1007\/978-1-0716-1460-0_16","volume":"2314","author":"AI Wong","year":"2021","unstructured":"Wong AI, Rock JM (2021) CRISPR interference (CRISPRi) for targeted gene silencing in Mycobacteria. Methods Mol Biol 2314:343\u2013364","journal-title":"Methods Mol Biol"},{"issue":"1","key":"2_CR235","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1128\/IAI.67.1.327-336.1999","volume":"67","author":"DK Wong","year":"1999","unstructured":"Wong DK, Lee BY, Horwitz MA, Gibson BW (1999) Identification of fur, aconitase, and other proteins expressed by Mycobacterium tuberculosis under conditions of low and high concentrations of iron by combined two-dimensional gel electrophoresis and mass spectrometry. Infect Immun 67(1):327\u2013336","journal-title":"Infect Immun"},{"issue":"8","key":"2_CR236","doi-asserted-by":"publisher","first-page":"1491","DOI":"10.1074\/mcp.M116.065771","volume":"16","author":"FL Wu","year":"2017","unstructured":"Wu FL, Liu Y, Jiang HW, Luan YZ, Zhang HN, He X, Xu ZW, Hou JL, Ji LY, Xie Z, Czajkowsky DM, Yan W, Deng JY, Bi LJ, Zhang XE, Tao SC (2017) The Ser\/Thr protein kinase protein-protein interaction map of M. Tuberculosis. Mol Cell Proteomics 16(8):1491\u20131506","journal-title":"Mol Cell Proteomics"},{"key":"2_CR237","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s12953-024-00235-y","volume":"22","author":"YL Wu","year":"2024","unstructured":"Wu YL, Li YT, Liu GB, Wu JL, Liu XR, Gao XX, Huang QD, Liang J, Ouyang JY, Ding YR, Wu JY, Lu YB, Gao YC, Cai XZ, Zhang JA (2024) LC\u2013MS-based quantitation of proteomic changes induced by Norcantharidin in MTB-treated macrophages. Proteome Sci 22:13","journal-title":"Proteome Sci"},{"key":"2_CR238","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1038\/s41392-023-01589-z","volume":"8","author":"X Xie","year":"2023","unstructured":"Xie X, Yu T, Li X, Zhang N, Foster LJ, Peng C, Huang W, He G (2023) Recent advances in targeting the \"undruggable\" proteins: from drug discovery to clinical trials. Signal Transduct Target Ther 8:335","journal-title":"Signal Transduct Target Ther"},{"issue":"47","key":"2_CR239","doi-asserted-by":"publisher","first-page":"eadd5907","DOI":"10.1126\/sciadv.add5907","volume":"8","author":"MY Yan","year":"2022","unstructured":"Yan MY, Zheng D, Li SS, Ding XY, Wang CL, Guo XP, Zhan L, Jin Q, Yang J, Sun YC (2022) Application of combined CRISPR screening for genetic and chemical-genetic interaction profiling in Mycobacterium tuberculosis. Sci Adv 8(47):eadd5907","journal-title":"Sci Adv"},{"key":"2_CR240","doi-asserted-by":"publisher","first-page":"5413903","DOI":"10.1155\/2016\/5413903","volume":"2016","author":"H Yang","year":"2016","unstructured":"Yang H, Tang H, Chen XX, Zhang CJ, Zhu PP, Ding H, Chen W, Lin H (2016) Identification of secretory proteins in Mycobacterium tuberculosis using pseudo amino acid composition. Biomed Res Int 2016:5413903","journal-title":"Biomed Res Int"},{"issue":"5","key":"2_CR241","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.353","volume":"4","author":"J Yang","year":"2023","unstructured":"Yang J, Zhang L, Qiao W, Luo Y (2023) Mycobacterium tuberculosis: pathogenesis and therapeutic targets. MedComm 4(5):e353","journal-title":"MedComm"},{"issue":"3","key":"2_CR242","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellin.2024.100163","volume":"3","author":"Y Yang","year":"2024","unstructured":"Yang Y, Chen YZ, Xia T (2024) Optimizing antigen selection for the development of tuberculosis vaccines. Cell Insight 3(3):100163","journal-title":"Cell Insight"},{"issue":"3","key":"2_CR243","first-page":"223","volume":"2","author":"MK Yazdi","year":"2018","unstructured":"Yazdi MK, Beheshtnejad AH, Hedayatpour A, Sharifi-Yazdi S, Mehrani F (2018) Comparative study of Mycobacterium tuberculosis and Mycobacterium bovis protein profiles. J Surgery Med 2(3):223\u2013227","journal-title":"J Surgery Med"},{"key":"2_CR244","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.550760","volume":"11","author":"SA Yimer","year":"2020","unstructured":"Yimer SA, Kalayou S, Homberset H, Birhanu AG, Riaz T, Zegeye ED, Lutter T, Abebe M, Holm-Hansen C, Aseffa A, T\u00f8njum T (2020) Lineage-specific proteomic signatures in the Mycobacterium tuberculosis complex reveal differential abundance of proteins involved in virulence, DNA repair, CRISPR-Cas, bioenergetics and lipid metabolism. Front Microbiol 11:550760","journal-title":"Front Microbiol"},{"key":"2_CR245","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.chroma.2012.07.004","volume":"1253","author":"LL Yu","year":"2012","unstructured":"Yu LL, Sun Y (2012) Trace adsorption of positively charged proteins onto Sepharose FF and Sepharose FF-based anion exchangers. J Chromatogr A 1253:105\u2013109","journal-title":"J Chromatogr A"},{"issue":"3","key":"2_CR246","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1021\/ac00099a020","volume":"67","author":"KS Yun","year":"1995","unstructured":"Yun KS, Zhu C, Parcher JF (1995) (1995). Theoretical relationships between the void volume, mobile phase volume, retention volume, adsorption, and Gibbs free energy in chromatographic processes. Anal Chem 67(3):613\u2013619","journal-title":"Anal Chem"},{"key":"2_CR247","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1038\/s44259-025-00107-1","volume":"3","author":"R Zein-Eddine","year":"2025","unstructured":"Zein-Eddine R, Le Meur A, Skouloubris S, Jelsbak L, Refr\u00e9gier G, Myllykallio H (2025) Genome wide analyses reveal the role of mutator phenotypes in Mycobacterium tuberculosis drug resistance emergence. NPJ Antimicrobial Resist 3:35","journal-title":"NPJ Antimicrobial Resist"},{"issue":"11","key":"2_CR248","doi-asserted-by":"publisher","first-page":"1276","DOI":"10.5588\/ijtld.15.0389","volume":"19","author":"Y Zhang","year":"2015","unstructured":"Zhang Y, Yew WW (2015) Mechanisms of drug resistance in Mycobacterium tuberculosis: update 2015. Int J Tuberc Lung Dis 19(11):1276\u20131289","journal-title":"Int J Tuberc Lung Dis"},{"key":"2_CR1025","doi-asserted-by":"crossref","unstructured":"Zhang W, Li Z, Sun Y, Cui P, Liang J, Xing Q et al (2022) Cryo-EM structure of mycobacterium tuberculosis 50S ribosomal subunit bound with clarithromycin reveals dynamic and specific interactions with macrolides. Emerg Microbes Infect 11(1):293\u2013305. https:\/\/doi.org\/10.1080\/22221751.2021.2022439. PMID:34935599; PMCID:PMC8786254","DOI":"10.1080\/22221751.2021.2022439"},{"key":"2_CR249","doi-asserted-by":"publisher","first-page":"1449844","DOI":"10.3389\/fmicb.2024.1449844","volume":"15","author":"X Zhang","year":"2024","unstructured":"Zhang X, Zhang D, Zhang X, Zhang X (2024) Artificial intelligence applications in the diagnosis and treatment of bacterial infections. Front Microbiol 15:1449844","journal-title":"Front Microbiol"},{"key":"2_CR250","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1186\/1471-2164-12-40","volume":"12","author":"J Zheng","year":"2011","unstructured":"Zheng J et al (2011) Combing blue native polyacrylamide gel electrophoresis with liquid chromatography tandem mass spectrometry as an effective strategy for analyzing potential membrane protein complexes of Mycobacterium bovis bacillus Calmette-Gu\u00e9rin. BMC Genomics 12:40","journal-title":"BMC Genomics"},{"issue":"1","key":"2_CR251","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.419","volume":"5","author":"L Zhuang","year":"2024","unstructured":"Zhuang L, Yang L, Li L, Ye Z, Gong W (2024) Mycobacterium tuberculosis: immune response, biomarkers, and therapeutic intervention. MedComm 5(1):e419","journal-title":"MedComm"}],"container-title":["Advances in Experimental Medicine and Biology","Proteins in Mycobacterium Tuberculosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-031-96883-9_2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T06:09:27Z","timestamp":1779430167000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-031-96883-9_2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,10]]},"ISBN":["9783031968822","9783031968839"],"references-count":280,"URL":"https:\/\/doi.org\/10.1007\/978-3-031-96883-9_2","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,10]]},"assertion":[{"value":"10 November 2025","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}