{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T18:03:52Z","timestamp":1771092232681,"version":"3.50.1"},"publisher-location":"Cham","reference-count":27,"publisher":"Springer Nature Switzerland","isbn-type":[{"value":"9783032033932","type":"print"},{"value":"9783032033949","type":"electronic"}],"license":[{"start":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T00:00:00Z","timestamp":1763510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T00:00:00Z","timestamp":1763510400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026]]},"DOI":"10.1007\/978-3-032-03394-9_48","type":"book-chapter","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T13:29:05Z","timestamp":1763472545000},"page":"501-506","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long-Term Health Outcomes of Children Born After In Vitro Fertilization (IVF): A Narrative Review"],"prefix":"10.1007","author":[{"given":"Anastasia-Evanthia","family":"Kouklamani-Giannouli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelia","family":"Pratsoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodoros N.","family":"Sergentanis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Artemis K.","family":"Tsitsika","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,11,19]]},"reference":[{"issue":"1","key":"48_CR1","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1001\/jama.2013.7222","volume":"310","author":"A Iliadou","year":"2013","unstructured":"Iliadou A, Nygren K-G, Sandin S et al (2013) Autism and mental retardation among offspring born after in vitro fertilization. JAMA 310(1):75\u201384","journal-title":"JAMA"},{"key":"48_CR2","doi-asserted-by":"publisher","first-page":"100355","DOI":"10.1016\/j.ssmph.2019.100355","volume":"7","author":"A Barbusciaa","year":"2019","unstructured":"Barbusciaa A, Myrskyl\u00e4a M, Goisisa A (2019) The psychosocial health of children born after medically assisted reproduction: evidence from the UK millennium cohort study. SSM \u2013 Population Health 7:100355","journal-title":"SSM \u2013 Population Health"},{"issue":"2","key":"48_CR3","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1080\/03009734.2020.1729904","volume":"125","author":"C Bergha","year":"2020","unstructured":"Bergha C, Wennerholma U-B (2020) Long-term health of children conceived after assisted reproductive technology. Ups J Med Sci 125(2):152\u2013157","journal-title":"Ups J Med Sci"},{"key":"48_CR4","doi-asserted-by":"publisher","unstructured":"Berntsen S, S\u00f6derstr\u00f6m-Anttila V, Wennerholm U-B, Laivuori H, Loft A, Oldereid NB et al (2019) The health of children conceived by ART: 'the chicken or the egg? 25(2):137\u2013158. https:\/\/doi.org\/10.1093\/humupd\/dmz001","DOI":"10.1093\/humupd\/dmz001"},{"issue":"1","key":"48_CR5","doi-asserted-by":"crossref","first-page":"15","DOI":"10.31083\/j.jin2301015","volume":"23","author":"A Cavero-Ibiricu","year":"2024","unstructured":"Cavero-Ibiricu A, Canelas-Fernandez J, Gomez-Acebo I, Alonso-Molero J, Mart\u00ednez-Jimenez D, Llorca J, Cabero-Perez MJ, Dierssen-Sotos T (2024) Association between assisted reproductive technology and cerebral palsy: a meta-analysis. J Inte Neurosci 23(1):15","journal-title":"J Inte Neurosci"},{"key":"48_CR6","volume-title":"Understanding long-term outcome from the patients\u2019 perspective: a mixed methods naturalistic study on inpatient psychotherapy","author":"M De Smet","year":"2018","unstructured":"Melissa De Smet, Reitske Maganck. Understanding long-term outcome from the patients\u2019 perspective: a mixed methods naturalistic study on inpatient psychotherapy. 2018"},{"key":"48_CR7","unstructured":"EUROSTAT (2024) Fertility statistics. https:\/\/ec.europa.eu\/eurostat\/statistics-explained\/index.php?title=Fertility_statistics"},{"key":"48_CR8","doi-asserted-by":"publisher","unstructured":"Graham ME, Jelin A, Hoon AH Jr, Floet AMW, Levey E, Graham EM (2023) Assisted reproductive technology: Short- and long-term outcomes. 65(1):38\u201349. https:\/\/doi.org\/10.1111\/dmcn.15332","DOI":"10.1111\/dmcn.15332"},{"key":"48_CR9","volume-title":"Cardiovascular and metabolic profiles of offspring conceived by assisted reproductive technologies: a systematic review and meta-analysis","author":"X-Y Guo","year":"2017","unstructured":"Xiao-Yan Guo, Xin-Mei Liu, Li Jin, Ting-Ting Wang, Kamran Ullah, Jian-Zhong Sheng et al. Cardiovascular and metabolic profiles of offspring conceived by assisted reproductive technologies: a systematic review and meta-analysis, 2017. (pubmed)"},{"issue":"3","key":"48_CR10","doi-asserted-by":"publisher","first-page":"244","DOI":"10.1093\/humupd\/dmt002","volume":"19","author":"R Hart","year":"2013","unstructured":"Hart R, Norman RJ (2013) The longer-term health outcomes for children born as a result of IVF treatment. Part II\u2013mental health and development outcomes. Hum Reprod Update 19(3):244\u2013250","journal-title":"Hum Reprod Update"},{"key":"48_CR11","doi-asserted-by":"publisher","first-page":"1045762","DOI":"10.3389\/frph.2022.1045762","volume":"4","author":"RJ Hart","year":"2022","unstructured":"Hart RJ, Wijs LA (2022) The longer-term effects of IVF on offspring from childhood to adolescence. Front Reprod Health 4:1045762","journal-title":"Front Reprod Health"},{"issue":"11","key":"48_CR12","doi-asserted-by":"publisher","first-page":"2193","DOI":"10.1093\/humrep\/dez202","volume":"34","author":"KR Heineman","year":"2019","unstructured":"Heineman KR, Kuiper DB, van Gemert SLB, Heineman MJ, Hadders-Algra M (2019) Cognitive and behavioural outcome of children born after IVF at age 9 years. Hum Reprod 34(11):2193\u20132200","journal-title":"Hum Reprod"},{"issue":"1","key":"48_CR13","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1001\/archpediatrics.2008.507","volume":"163","author":"D Hvidtj\u00f8rn","year":"2009","unstructured":"Hvidtj\u00f8rn D, Schieve L, Schendel D et al (2009) Cerebral palsy, autism Spectrum disorders, and developmental delay in children born after assisted conception; a systematic review and meta-analysis. Arch Pediatr Adolesc Med 163(1):72\u201383","journal-title":"Arch Pediatr Adolesc Med"},{"key":"48_CR14","doi-asserted-by":"publisher","first-page":"497e502","DOI":"10.1136\/jech.2009.093823","volume":"65","author":"D Hvidtj\u00f8rn","year":"2011","unstructured":"Hvidtj\u00f8rn D, Grove J, Schendel D, Schieve LA, Sv\u00e6rke C, Ernst E, Thorsen P (2011) Risk of autism spectrum disorders in children born after assisted conception: a population-based follow-up study. J Epidemiol Community Health 65:497e502","journal-title":"J Epidemiol Community Health"},{"key":"48_CR15","volume-title":"Assisted reproductive technology (ART) techniques","author":"M Jain","year":"2024","unstructured":"Jain M, Singh M (2024) Assisted reproductive technology (ART) techniques. StatPearls Publishing LLC"},{"key":"48_CR16","unstructured":"National Cancer Institute (NIH) (n.d.) Available from: https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/long-term-side-effect"},{"issue":"7","key":"48_CR17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0272064","volume":"17","author":"B Penova-VeselinovicI","year":"2022","unstructured":"Penova-VeselinovicI B, Wijs LA, Yovich JL, Burton P, Hart RJ (2022) Cohort profile: the growing up healthy study (GUHS)\u2014a prospective and observational cohort study investigating the long-term health outcomes of offspring conceived after assisted reproductive technologies. PLoS One 17(7):e0272064","journal-title":"PLoS One"},{"issue":"3","key":"48_CR18","doi-asserted-by":"publisher","first-page":"Pt. 1","DOI":"10.1016\/j.fertnstert.2023.04.022","volume":"120","author":"A Pinborg","year":"2023","unstructured":"Pinborg A, Wennerholm U-B, Bergh C (2023) Long-term outcomes for children conceived by assisted reproductive technology. Fertil Steril 120(3):Pt. 1","journal-title":"Fertil Steril"},{"key":"48_CR19","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2020.105021","volume":"144","author":"N Shachor","year":"2020","unstructured":"Shachor N, Wainstock T, Sheiner E, Harlev A (2020) Fertility treatments and gastrointestinal morbidity of the offspring. Early Hum Dev 144:105021","journal-title":"Early Hum Dev"},{"key":"48_CR20","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.jpeds.2018.08.070","volume":"204","author":"SR Shiloh","year":"2019","unstructured":"Shiloh SR, Sheiner E, Wainstock T, Walfisch A, Segal I, Landau D et al (2019) Long-term cardiovascular morbidity in children born following fertility treatment. J Pediatr 204:84\u201388.e2","journal-title":"J Pediatr"},{"issue":"4","key":"48_CR21","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1093\/humrep\/dey394","volume":"34","author":"M Spaan","year":"2019","unstructured":"Spaan M, van den Belt-Dusebout AW, van den Heuvel-Eibrink MM, Hauptmann M, Lambalk CB, Burger CW et al (2019) Risk of cancer in children and young adults conceived by assisted reproductive technology. Hum Reprod 34(4):740\u2013750","journal-title":"Hum Reprod"},{"key":"48_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.earlhumdev.2020.105132","volume":"148","author":"N Steiner","year":"2020","unstructured":"Steiner N, Wainstock T, Sheiner E, Walfisch A, Segal I, Haim A et al (2020) Long-term endocrine disorders in children born from pregnancies conceived following fertility treatments. Early Hum Dev 148:105132","journal-title":"Early Hum Dev"},{"issue":"11","key":"48_CR23","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.43954","volume":"6","author":"MP Velez","year":"2023","unstructured":"Velez MP, Dayan N, Shellenberger J, Pudwell J, Kapoor D, Vigod SN, Ray JG (2023) Infertility and risk of autism Spectrum disorder in children. JAMA Netw Open 6(11):e2343954","journal-title":"JAMA Netw Open"},{"key":"48_CR24","volume":"144","author":"LA Wijs","year":"2020","unstructured":"Wijs LA, Doherty DA, Keelan JA, Panicker V, Burton P, Yovich JL et al (2020) Offspring conceived through ART have normal thyroid function in adolescence and as young adults. Early Hum Dev 144:105021","journal-title":"Early Hum Dev"},{"issue":"8","key":"48_CR25","doi-asserted-by":"publisher","first-page":"1880","DOI":"10.1093\/humrep\/deac122","volume":"37","author":"LA Wijs","year":"2022","unstructured":"Wijs LA, Doherty DA, Keelan JA, Burton P, Yovich JL, Beilin L et al (2022a) Comparison of the cardiometabolic profiles of adolescents conceived through ART with those of a non-ART cohort. Hum Reprod 37(8):1880\u20131895","journal-title":"Hum Reprod"},{"issue":"6","key":"48_CR26","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1016\/j.rbmo.2022.07.007","volume":"45","author":"LA Wijs","year":"2022","unstructured":"Wijs LA, Doherty DA, Keelan JA, Sly PD, Holt PG, Hart RJ (2022b) Asthma and allergies in a cohort of adolescents conceived with ART. Reprod Biomed Online 45(6):1255\u20131265","journal-title":"Reprod Biomed Online"},{"issue":"1","key":"48_CR27","first-page":"15","volume":"23","author":"Z Zeng","year":"2024","unstructured":"Zeng Z, Wang Z, Pengfei Y, Wang Y, Pei Y, Dai Y, Liu Y, Yang Y (2024) The association between assisted reproductive technologies and neurodevelopmental disorders in offspring: an overview of current evidence. Journal of integrated. Neuroscience 23(1):15","journal-title":"Neuroscience"}],"container-title":["Advances in Experimental Medicine and Biology","GeNeDIS 2024"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-032-03394-9_48","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T17:21:26Z","timestamp":1771089686000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-032-03394-9_48"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,19]]},"ISBN":["9783032033932","9783032033949"],"references-count":27,"URL":"https:\/\/doi.org\/10.1007\/978-3-032-03394-9_48","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,19]]},"assertion":[{"value":"19 November 2025","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}},{"value":"GeNeDIS","order":1,"name":"conference_acronym","label":"Conference Acronym","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"International\u00a0Genomics, Neuroscience, Therapeutics and Data\u00a0Innovation\u00a0Summit","order":2,"name":"conference_name","label":"Conference Name","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Athens","order":3,"name":"conference_city","label":"Conference City","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Greece","order":4,"name":"conference_country","label":"Conference Country","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"2024","order":5,"name":"conference_year","label":"Conference Year","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"17 October 2024","order":7,"name":"conference_start_date","label":"Conference Start Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"20 October 2024","order":8,"name":"conference_end_date","label":"Conference End Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"genedis-12024","order":10,"name":"conference_id","label":"Conference ID","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"https:\/\/easychair.org\/cfp\/GeNeDis2024","order":11,"name":"conference_url","label":"Conference URL","group":{"name":"ConferenceInfo","label":"Conference Information"}}]}}