{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T03:20:34Z","timestamp":1769224834186,"version":"3.49.0"},"publisher-location":"Cham","reference-count":23,"publisher":"Springer Nature Switzerland","isbn-type":[{"value":"9783032103888","type":"print"},{"value":"9783032103895","type":"electronic"}],"license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026]]},"DOI":"10.1007\/978-3-032-10389-5_24","type":"book-chapter","created":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T21:04:14Z","timestamp":1769202254000},"page":"203-209","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Unravelling the Connection Between Reduced Mobility and Mild Cognitive Impairment in Chronic Pain Patients Through Cluster Analysis"],"prefix":"10.1007","author":[{"given":"Masamichi","family":"Moriya","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Kitahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Karako","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaoru","family":"Sakatani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,24]]},"reference":[{"issue":"2","key":"24_CR1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0192623","volume":"13","author":"E B\u00e4ckryd","year":"2018","unstructured":"B\u00e4ckryd E, Persson EB, Larsson AI et al (2018) Chronic pain patients can be classified into four groups: clustering-based discriminant analysis of psychometric data from 4665 patients referred to a multidisciplinary pain centre (a SQRP study). PLoS One 13(2):e0192623","journal-title":"PLoS One"},{"issue":"3","key":"24_CR2","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1038\/ijo.2017.231","volume":"42","author":"WA Banks","year":"2018","unstructured":"Banks WA, Farr SA, Salameh TS et al (2018) Triglycerides cross the blood-brain barrier and induce central leptin and insulin receptor resistance. Int J Obes 42(3):391\u2013397","journal-title":"Int J Obes"},{"issue":"1","key":"24_CR3","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-019-1608-z","volume":"16","author":"S Cao","year":"2019","unstructured":"Cao S, Fisher DW, Yu T et al (2019) The link between chronic pain and Alzheimer's disease. Review. J Neuroinflammation 16(1):204","journal-title":"J Neuroinflammation"},{"issue":"1","key":"24_CR4","doi-asserted-by":"publisher","DOI":"10.1186\/s12929-020-00658-7","volume":"27","author":"PS Chen","year":"2020","unstructured":"Chen PS, Chiu WT, Hsu PL et al (2020) Pathophysiological implications of hypoxia in human diseases. J Biomed Sci 27(1):63","journal-title":"J Biomed Sci"},{"issue":"5","key":"24_CR5","doi-asserted-by":"publisher","first-page":"2628","DOI":"10.1210\/en.2007-1722","volume":"149","author":"SA Farr","year":"2008","unstructured":"Farr SA, Yamada KA, Butterfield DA et al (2008) Obesity and hypertriglyceridemia produce cognitive impairment. Endocrinology 149(5):2628\u20132636","journal-title":"Endocrinology"},{"key":"24_CR6","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2023.101955","volume":"88","author":"Y Guo","year":"2023","unstructured":"Guo Y, Guan T, Shafiq K et al (2023) Mitochondrial dysfunction in aging. Ageing Res Rev 88:101955","journal-title":"Ageing Res Rev"},{"issue":"6","key":"24_CR7","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1016\/j.cmet.2005.05.001","volume":"1","author":"RD Guzy","year":"2005","unstructured":"Guzy RD, Hoyos B, Robin E et al (2005) Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing. Cell Metab 1(6):401\u2013408","journal-title":"Cell Metab"},{"issue":"3","key":"24_CR8","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1097\/AJP.0000000000000536","volume":"34","author":"DM Higgins","year":"2018","unstructured":"Higgins DM, Martin AM, Baker DG et al (2018) The relationship between chronic pain and neurocognitive function: a systematic review. Clin J Pain 34(3):262\u2013275","journal-title":"Clin J Pain"},{"issue":"6","key":"24_CR9","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1212\/WNL.0b013e31829e701d","volume":"81","author":"CH Hong","year":"2013","unstructured":"Hong CH, Falvey C, Harris TB et al (2013) Anemia and risk of dementia in older adults: findings from the Health ABC study. Neurology 81(6):528\u2013533","journal-title":"Neurology"},{"issue":"10","key":"24_CR10","doi-asserted-by":"publisher","first-page":"4343","DOI":"10.1038\/s41380-022-01655-y","volume":"27","author":"SY Huang","year":"2022","unstructured":"Huang SY, Li YZ, Zhang YR et al (2022) Sleep, physical activity, sedentary behavior, and risk of incident dementia: a prospective cohort study of 431,924 UK biobank participants. Mol Psychiatry 27(10):4343\u20134354","journal-title":"Mol Psychiatry"},{"key":"24_CR11","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1007\/978-3-030-34461-0_13","volume":"1232","author":"Y Komuro","year":"2020","unstructured":"Komuro Y, Oyama K, Hu L et al (2020) Relationship between cognitive dysfunction and systemic metabolic disorders in elderly: dementia might be a systematic disease. Adv Exp Med Biol 1232:91\u201397","journal-title":"Adv Exp Med Biol"},{"issue":"5","key":"24_CR12","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1159\/000114761","volume":"14","author":"NT Mathew","year":"1976","unstructured":"Mathew NT, Meyer JS, Achari AN et al (1976) Hyperlipidemic neuropathy and dementia. Eur Neurol 14(5):370\u2013382","journal-title":"Eur Neurol"},{"key":"24_CR13","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2024.1344190","volume":"15","author":"M Moriya","year":"2024","unstructured":"Moriya M, Hu L, Sakatani K et al (2024) Estimation of cognitive impairment in chronic pain patients and characteristics of estimated mild cognitive impairment. Front Neurol 15:1344190","journal-title":"Front Neurol"},{"issue":"5","key":"24_CR14","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1016\/j.tics.2021.01.001","volume":"25","author":"CE Phelps","year":"2021","unstructured":"Phelps CE, Navratilova E, Porreca F (2021) Cognition in the chronic pain experience: preclinical insights. Trends Cogn Sci 25(5):365\u2013376","journal-title":"Trends Cogn Sci"},{"issue":"10","key":"24_CR15","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1001\/jama.2023.15231","volume":"330","author":"DA Raichlen","year":"2023","unstructured":"Raichlen DA, Aslan DH, Sayre MK et al (2023) Sedentary behavior and incident dementia among older adults. JAMA 330(10):934\u2013940","journal-title":"JAMA"},{"issue":"2","key":"24_CR16","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1097\/j.pain.0000000000002047","volume":"162","author":"I Rouch","year":"2021","unstructured":"Rouch I, Edjolo A, Laurent B et al (2021) Association between chronic pain and long-term cognitive decline in a population-based cohort of elderly participants. Pain 162(2):552\u2013560","journal-title":"Pain"},{"issue":"11","key":"24_CR17","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.588140","volume":"14","author":"K Sakatani","year":"2020","unstructured":"Sakatani K, Oyama K, Hu L (2020) Deep learning-based screening test for cognitive impairment using basic blood test data for health examination. Front Neurol 14(11):588140","journal-title":"Front Neurol"},{"issue":"1","key":"24_CR18","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.ynpai.2017.04.003","volume":"17","author":"E Senba","year":"2017","unstructured":"Senba E, Kami K (2017) A new aspect of chronic pain as a lifestyle-related disease. Neurobiol Pain 17(1):6\u201315","journal-title":"Neurobiol Pain"},{"issue":"12","key":"24_CR19","doi-asserted-by":"publisher","first-page":"2302","DOI":"10.1038\/s41380-018-0209-z","volume":"23","author":"M Tajerian","year":"2018","unstructured":"Tajerian M, Hung V, Nguyen H et al (2018) The hippocampal extracellular matrix regulates pain and memory after injury. Mol Psychiatry 23(12):2302\u20132313","journal-title":"Mol Psychiatry"},{"issue":"3","key":"24_CR20","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/S0304-3959(99)00242-0","volume":"85","author":"JWS Vlaeyen","year":"2000","unstructured":"Vlaeyen JWS, Linton SJ (2000) Fear-avoidance and its consequences in chronic musculoskeletal pain: a state of the art. Pain 85(3):317\u2013332","journal-title":"Pain"},{"issue":"1","key":"24_CR21","doi-asserted-by":"publisher","first-page":"125","DOI":"10.3233\/JAD-230483","volume":"96","author":"J Wang","year":"2023","unstructured":"Wang J, Wang C, Li X et al (2023) Association of Anemia with cognitive function and dementia among older adults: the role of inflammation. J Alzheimer's Dis 96(1):125\u2013134","journal-title":"J Alzheimer's Dis"},{"issue":"8","key":"24_CR22","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1001\/jamainternmed.2017.1622","volume":"177","author":"EL Whitlock","year":"2017","unstructured":"Whitlock EL, Diaz-Ramirez LG, Glymour MM et al (2017) Association between persistent pain and memory decline and dementia in a longitudinal cohort of elders. JAMA Intern Med 177(8):1146\u20131153","journal-title":"JAMA Intern Med"},{"key":"24_CR23","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1016\/j.jad.2022.07.008","volume":"314","author":"YR Zhang","year":"2022","unstructured":"Zhang YR, Xu W, Zhang W et al (2022) Modifiable risk factors for incident dementia and cognitive impairment: an umbrella review of evidence. J Affect Disord 314:160\u2013167","journal-title":"J Affect Disord"}],"container-title":["Advances in Experimental Medicine and Biology","Oxygen Transport to Tissue XLVI"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-032-10389-5_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T22:02:44Z","timestamp":1769205764000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-032-10389-5_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"ISBN":["9783032103888","9783032103895"],"references-count":23,"URL":"https:\/\/doi.org\/10.1007\/978-3-032-10389-5_24","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"value":"0065-2598","type":"print"},{"value":"2214-8019","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"24 January 2026","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}},{"value":"ISOTT","order":1,"name":"conference_acronym","label":"Conference Acronym","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"International Society on Oxygen Transport to Tissue","order":2,"name":"conference_name","label":"Conference Name","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Socorro","order":3,"name":"conference_city","label":"Conference City","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Mexico","order":4,"name":"conference_country","label":"Conference Country","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"2024","order":5,"name":"conference_year","label":"Conference Year","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"9 June 2024","order":7,"name":"conference_start_date","label":"Conference Start Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"14 June 2024","order":8,"name":"conference_end_date","label":"Conference End Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"isott2024","order":10,"name":"conference_id","label":"Conference ID","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"https:\/\/www.isott2024.com\/","order":11,"name":"conference_url","label":"Conference URL","group":{"name":"ConferenceInfo","label":"Conference Information"}}]}}