{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T11:20:09Z","timestamp":1771586409650,"version":"3.50.1"},"publisher-location":"Cham","reference-count":136,"publisher":"Springer Nature Switzerland","isbn-type":[{"value":"9783032168320","type":"print"},{"value":"9783032168337","type":"electronic"}],"license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026]]},"DOI":"10.1007\/978-3-032-16833-7_19","type":"book-chapter","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T10:36:11Z","timestamp":1771583771000},"page":"463-482","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Golgi Fragmentation as a Potential Link Between SARS-CoV-2 Infection and Alzheimer\u2019s Disease: Mechanisms and Implications for Neurodegeneration in Long COVID"],"prefix":"10.1007","author":[{"given":"Yanzhuang","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sam","family":"Gandy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,2,21]]},"reference":[{"key":"19_CR1","doi-asserted-by":"publisher","first-page":"340","DOI":"10.3389\/fnins.2015.00340","volume":"9","author":"G Joshi","year":"2015","unstructured":"Joshi G, Bekier ME 2nd, Wang Y (2015) Golgi fragmentation in Alzheimer\u2019s disease. Front Neurosci 9:340. https:\/\/doi.org\/10.3389\/fnins.2015.00340","journal-title":"Front Neurosci"},{"issue":"13","key":"19_CR2","doi-asserted-by":"publisher","first-page":"E1230","DOI":"10.1073\/pnas.1320192111","volume":"111","author":"G Joshi","year":"2014","unstructured":"Joshi G, Chi Y, Huang Z, Wang Y (2014) Abeta-induced Golgi fragmentation in Alzheimer\u2019s disease enhances Abeta production. Proc Natl Acad Sci USA 111(13):E1230\u2013E1239. https:\/\/doi.org\/10.1073\/pnas.1320192111","journal-title":"Proc Natl Acad Sci USA"},{"issue":"3","key":"19_CR3","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1002\/bies.201400116","volume":"37","author":"G Joshi","year":"2015","unstructured":"Joshi G, Wang Y (2015) Golgi defects enhance APP amyloidogenic processing in Alzheimer\u2019s disease. Bioessays 37(3):240\u2013247. https:\/\/doi.org\/10.1002\/bies.201400116","journal-title":"Bioessays"},{"issue":"5\u20136","key":"19_CR4","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1007\/s004180050257","volume":"109","author":"NK Gonatas","year":"1998","unstructured":"Gonatas NK, Gonatas JO, Stieber A (1998) The involvement of the Golgi apparatus in the pathogenesis of amyotrophic lateral sclerosis, Alzheimer\u2019s disease, and ricin intoxication. Histochem Cell Biol 109(5\u20136):591\u2013600. https:\/\/doi.org\/10.1007\/s004180050257","journal-title":"Histochem Cell Biol"},{"issue":"6","key":"19_CR5","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1016\/j.chom.2020.11.003","volume":"28","author":"M Cortese","year":"2020","unstructured":"Cortese M, Lee JY, Cerikan B, Neufeldt CJ, Oorschot VMJ, Kohrer S et al (2020) Integrative imaging reveals SARS-CoV-2-induced reshaping of subcellular morphologies. Cell Host Microbe 28(6):853\u201366 e5. https:\/\/doi.org\/10.1016\/j.chom.2020.11.003","journal-title":"Cell Host Microbe"},{"issue":"1","key":"19_CR6","doi-asserted-by":"publisher","first-page":"eabl4895","DOI":"10.1126\/sciadv.abl4895","volume":"8","author":"KM Scherer","year":"2022","unstructured":"Scherer KM, Mascheroni L, Carnell GW, Wunderlich LCS, Makarchuk S, Brockhoff M et al (2022) SARS-CoV-2 nucleocapsid protein adheres to replication organelles before viral assembly at the Golgi\/ERGIC and lysosome-mediated egress. Sci Adv 8(1):eabl4895. https:\/\/doi.org\/10.1126\/sciadv.abl4895","journal-title":"Sci Adv"},{"key":"19_CR7","doi-asserted-by":"publisher","unstructured":"Zhang J, Kennedy A, de Melo Jorge DM, Xing L, Reid W, Bui S et al (2025) SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion. PLoS Pathog 21(6):e1013295. https:\/\/doi.org\/10.1371\/journal.ppat.1013295","DOI":"10.1371\/journal.ppat.1013295"},{"key":"19_CR8","doi-asserted-by":"publisher","unstructured":"Toader C, Eva L, Covache-Busuioc RA, Costin HP, Glavan LA, Corlatescu AD et al (2023) Unraveling the multifaceted role of the Golgi apparatus: insights into neuronal plasticity, development, neurogenesis, Alzheimer\u2019s disease, and SARS-CoV-2 interactions. Brain Sci 13(10). https:\/\/doi.org\/10.3390\/brainsci13101363","DOI":"10.3390\/brainsci13101363"},{"key":"19_CR9","doi-asserted-by":"publisher","unstructured":"Reiken S, Sittenfeld L, Dridi H, Liu Y, Liu X, Marks AR (2022) Alzheimer\u2019s-like signaling in brains of COVID-19 patients. Alzheimers Dement. https:\/\/doi.org\/10.1002\/alz.12558","DOI":"10.1002\/alz.12558"},{"key":"19_CR10","doi-asserted-by":"publisher","unstructured":"Rhodes CH, Priemer DS, Karlovich E, Perl DP, Goldman JE (2022) \u03b2-amyloid deposits in young COVID patients. SSRN Electronic Journal. https:\/\/doi.org\/10.2139\/SSRN.4003213","DOI":"10.2139\/SSRN.4003213"},{"issue":"22","key":"19_CR11","doi-asserted-by":"publisher","first-page":"4851","DOI":"10.1016\/j.cell.2023.09.013","volume":"186","author":"AC Wong","year":"2023","unstructured":"Wong AC, Devason AS, Umana IC, Cox TO, Dohnalova L, Litichevskiy L et al (2023) Serotonin reduction in post-acute sequelae of viral infection. Cell 186(22):4851\u201367 e20. https:\/\/doi.org\/10.1016\/j.cell.2023.09.013","journal-title":"Cell"},{"key":"19_CR12","doi-asserted-by":"publisher","first-page":"1147549","DOI":"10.3389\/fimmu.2023.1147549","volume":"14","author":"AAR Antar","year":"2023","unstructured":"Antar AAR, Yu T, Demko ZO, Hu C, Tornheim JA, Blair PW et al (2023) Long COVID brain fog and muscle pain are associated with longer time to clearance of SARS-CoV-2 RNA from the upper respiratory tract during acute infection. Front Immunol 14:1147549. https:\/\/doi.org\/10.3389\/fimmu.2023.1147549","journal-title":"Front Immunol"},{"issue":"11","key":"19_CR13","doi-asserted-by":"publisher","first-page":"2406","DOI":"10.1038\/s41591-022-02001-z","volume":"28","author":"E Xu","year":"2022","unstructured":"Xu E, Xie Y, Al-Aly Z (2022) Long-term neurologic outcomes of COVID-19. Nat Med 28(11):2406\u20132415. https:\/\/doi.org\/10.1038\/s41591-022-02001-z","journal-title":"Nat Med"},{"issue":"5","key":"19_CR14","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1038\/nri2971","volume":"11","author":"DB McGavern","year":"2011","unstructured":"McGavern DB, Kang SS (2011) Illuminating viral infections in the nervous system. Nat Rev Immunol 11(5):318\u2013329. https:\/\/doi.org\/10.1038\/nri2971","journal-title":"Nat Rev Immunol"},{"issue":"7","key":"19_CR15","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1016\/j.addr.2011.11.002","volume":"64","author":"JJ Lochhead","year":"2012","unstructured":"Lochhead JJ, Thorne RG (2012) Intranasal delivery of biologics to the central nervous system. Adv Drug Deliv Rev 64(7):614\u2013628. https:\/\/doi.org\/10.1016\/j.addr.2011.11.002","journal-title":"Adv Drug Deliv Rev"},{"key":"19_CR16","doi-asserted-by":"publisher","first-page":"8562805","DOI":"10.1155\/2016\/8562805","volume":"2016","author":"T Dahm","year":"2016","unstructured":"Dahm T, Rudolph H, Schwerk C, Schroten H, Tenenbaum T (2016) Neuroinvasion and inflammation in viral central nervous system infections. Mediat Inflamm 2016:8562805. https:\/\/doi.org\/10.1155\/2016\/8562805","journal-title":"Mediat Inflamm"},{"issue":"7","key":"19_CR17","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1021\/acschemneuro.0c00122","volume":"11","author":"AM Baig","year":"2020","unstructured":"Baig AM, Khaleeq A, Ali U, Syeda H (2020) Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host-virus interaction, and proposed neurotropic mechanisms. ACS Chem Neurosci 11(7):995\u2013998. https:\/\/doi.org\/10.1021\/acschemneuro.0c00122","journal-title":"ACS Chem Neurosci"},{"issue":"10","key":"19_CR18","doi-asserted-by":"publisher","first-page":"1379","DOI":"10.1021\/acschemneuro.0c00217","volume":"11","author":"S Gandhi","year":"2020","unstructured":"Gandhi S, Srivastava AK, Ray U, Tripathi PP (2020) Is the collapse of the respiratory center in the brain responsible for respiratory breakdown in COVID-19 patients? ACS Chem Neurosci 11(10):1379\u20131381","journal-title":"ACS Chem Neurosci"},{"issue":"1\u20132","key":"19_CR19","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.virusres.2007.06.016","volume":"130","author":"M Desforges","year":"2007","unstructured":"Desforges M, Miletti TC, Gagnon M, Talbot PJ (2007) Activation of human monocytes after infection by human coronavirus 229E. Virus Res 130(1\u20132):228\u2013240. https:\/\/doi.org\/10.1016\/j.virusres.2007.06.016","journal-title":"Virus Res"},{"issue":"2","key":"19_CR20","doi-asserted-by":"publisher","first-page":"168","DOI":"10.3390\/v11020168","volume":"11","author":"AA Stegelmeier","year":"2019","unstructured":"Stegelmeier AA, van Vloten JP, Mould RC, Klafuric EM, Minott JA, Wootton SK et al (2019) Myeloid cells during viral infections and inflammation. Viruses 11(2):168. https:\/\/doi.org\/10.3390\/v11020168","journal-title":"Viruses"},{"key":"19_CR21","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.569333","volume":"11","author":"H Rebholz","year":"2020","unstructured":"Rebholz H, Braun RJ, Ladage D, Knoll W, Kleber C, Hassel AW (2020) Loss of olfactory function-early indicator for Covid-19, other viral infections and neurodegenerative disorders. Front Neurol 11:569333. https:\/\/doi.org\/10.3389\/fneur.2020.569333","journal-title":"Front Neurol"},{"issue":"50","key":"19_CR22","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2111011118","volume":"118","author":"J Chen","year":"2021","unstructured":"Chen J, Fan J, Chen Z, Zhang M, Peng H, Liu J et al (2021) Nonmuscle myosin heavy chain IIA facilitates SARS-CoV-2 infection in human pulmonary cells. Proc Natl Acad Sci USA 118(50):e2111011118. https:\/\/doi.org\/10.1073\/pnas.2111011118","journal-title":"Proc Natl Acad Sci USA"},{"key":"19_CR23","doi-asserted-by":"publisher","unstructured":"Gao C, Zeng J, Jia N, Stavenhagen K, Matsumoto Y, Zhang H et al (2020) SARS-CoV-2 spike protein interacts with multiple innate immune receptors. bioRxiv: The Preprint Server for Biology. https:\/\/doi.org\/10.1101\/2020.07.29.227462","DOI":"10.1101\/2020.07.29.227462"},{"issue":"7","key":"19_CR24","doi-asserted-by":"publisher","first-page":"1156","DOI":"10.1021\/acscentsci.0c01537","volume":"7","author":"R Amraei","year":"2021","unstructured":"Amraei R, Yin W, Napoleon MA, Suder EL, Berrigan J, Zhao Q et al (2021) CD209L\/L-SIGN and CD209\/DC-SIGN act as receptors for SARS-CoV-2. ACS Cent Sci 7(7):1156\u20131165. https:\/\/doi.org\/10.1021\/acscentsci.0c01537","journal-title":"ACS Cent Sci"},{"issue":"6","key":"19_CR25","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1038\/s41422-022-00654-6","volume":"32","author":"Y Gu","year":"2022","unstructured":"Gu Y, Cao J, Zhang X, Gao H, Wang Y, Wang J et al (2022) Author Correction: Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2. Cell Res 32(6):600. https:\/\/doi.org\/10.1038\/s41422-022-00654-6","journal-title":"Cell Res"},{"issue":"2","key":"19_CR26","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.stem.2023.12.012","volume":"31","author":"L Yang","year":"2024","unstructured":"Yang L, Kim TW, Han Y, Nair MS, Harschnitz O, Zhu J et al (2024) SARS-CoV-2 infection causes dopaminergic neuron senescence. Cell Stem Cell 31(2):196\u2013211 e6. https:\/\/doi.org\/10.1016\/j.stem.2023.12.012","journal-title":"Cell Stem Cell"},{"issue":"5","key":"19_CR27","doi-asserted-by":"publisher","first-page":"2379","DOI":"10.1007\/s12035-020-02236-2","volume":"58","author":"M Dolatshahi","year":"2021","unstructured":"Dolatshahi M, Sabahi M, Aarabi MH (2021) Pathophysiological clues to how the emergent SARS-CoV-2 can potentially increase the susceptibility to neurodegeneration. Mol Neurobiol 58(5):2379\u20132394","journal-title":"Mol Neurobiol"},{"issue":"4","key":"19_CR28","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/j.nrl.2020.04.002","volume":"35","author":"PJ Serrano-Castro","year":"2020","unstructured":"Serrano-Castro PJ, Estivill-Torrus G, Cabezudo-Garcia P, Reyes-Bueno JA, Ciano Petersen N, Aguilar-Castillo MJ et al (2020) Impact of SARS-CoV-2 infection on neurodegenerative and neuropsychiatric diseases: a delayed pandemic? Neurologia (Engl Ed) 35(4):245\u2013251. https:\/\/doi.org\/10.1016\/j.nrl.2020.04.002","journal-title":"Neurologia (Engl Ed)"},{"issue":"5","key":"19_CR29","doi-asserted-by":"publisher","first-page":"716","DOI":"10.1002\/mds.28084","volume":"35","author":"A Lippi","year":"2020","unstructured":"Lippi A, Domingues R, Setz C, Outeiro TF, Krisko A (2020) SARS-CoV-2: at the crossroad between aging and neurodegeneration. Mov Disord 35(5):716","journal-title":"Mov Disord"},{"key":"19_CR30","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.bbrc.2021.03.100","volume":"554","author":"D Idrees","year":"2021","unstructured":"Idrees D, Kumar V (2021) SARS-CoV-2 spike protein interactions with amyloidogenic proteins: potential clues to neurodegeneration. Biochem Biophys Res Commun 554:94\u201398. https:\/\/doi.org\/10.1016\/j.bbrc.2021.03.100","journal-title":"Biochem Biophys Res Commun"},{"issue":"7","key":"19_CR31","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1002\/mds.28179","volume":"35","author":"U Gomez-Pinedo","year":"2020","unstructured":"Gomez-Pinedo U, Matias-Guiu J, Sanclemente-Alaman I, Moreno-Jimenez L, Montero-Escribano P, Matias-Guiu JA (2020) SARS-CoV-2 as a potential trigger of neurodegenerative diseases. Mov Disord 35(7):1104","journal-title":"Mov Disord"},{"issue":"1","key":"19_CR32","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1186\/s13024-022-00568-2","volume":"17","author":"Y Wang","year":"2022","unstructured":"Wang Y, Gandy S (2022) The Golgi apparatus: Site for convergence of COVID-19 brain fog and Alzheimer\u2019s disease? Mol Neurodegener 17(1):67. https:\/\/doi.org\/10.1186\/s13024-022-00568-2","journal-title":"Mol Neurodegener"},{"issue":"7816","key":"19_CR33","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1038\/s41586-020-2286-9","volume":"583","author":"DE Gordon","year":"2020","unstructured":"Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM et al (2020) A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature 583(7816):459\u2013468. https:\/\/doi.org\/10.1038\/s41586-020-2286-9","journal-title":"Nature"},{"key":"19_CR34","doi-asserted-by":"publisher","unstructured":"Oudshoorn D, Rijs K, Limpens R, Groen K, Koster AJ, Snijder EJ et al (2017) Expression and cleavage of middle east respiratory syndrome coronavirus nsp3\u20134 polyprotein induce the formation of double-membrane vesicles that mimic those associated with coronaviral rna replication. MBio 8(6). https:\/\/doi.org\/10.1128\/mBio.01658-17","DOI":"10.1128\/mBio.01658-17"},{"issue":"7915","key":"19_CR35","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1038\/s41586-022-04835-6","volume":"606","author":"S Ricciardi","year":"2022","unstructured":"Ricciardi S, Guarino AM, Giaquinto L, Polishchuk EV, Santoro M, Di Tullio G et al (2022) The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle. Nature 606(7915):761\u2013768. https:\/\/doi.org\/10.1038\/s41586-022-04835-6","journal-title":"Nature"},{"issue":"4","key":"19_CR36","doi-asserted-by":"publisher","first-page":"2003","DOI":"10.1021\/acs.analchem.0c03173","volume":"93","author":"M Sanda","year":"2021","unstructured":"Sanda M, Morrison L, Goldman R (2021) N- and O-glycosylation of the SARS-CoV-2 spike protein. Anal Chem 93(4):2003\u20132009. https:\/\/doi.org\/10.1021\/acs.analchem.0c03173","journal-title":"Anal Chem"},{"issue":"10","key":"19_CR37","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1038\/s41422-021-00545-2","volume":"31","author":"W Tian","year":"2021","unstructured":"Tian W, Li D, Zhang N, Bai G, Yuan K, Xiao H et al (2021) O-glycosylation pattern of the SARS-CoV-2 spike protein reveals an \u201cO-Follow-N\u201d rule. Cell Res 31(10):1123\u20131125. https:\/\/doi.org\/10.1038\/s41422-021-00545-2","journal-title":"Cell Res"},{"key":"19_CR38","doi-asserted-by":"publisher","unstructured":"Eymieux S, Uzbekov R, Rouille Y, Blanchard E, Hourioux C, Dubuisson J et al (2021) Secretory vesicles are the principal means of SARS-CoV-2 egress. Cells 10(8). https:\/\/doi.org\/10.3390\/cells10082047","DOI":"10.3390\/cells10082047"},{"issue":"6","key":"19_CR39","doi-asserted-by":"publisher","first-page":"1520","DOI":"10.1016\/j.cell.2020.10.039","volume":"183","author":"S Ghosh","year":"2020","unstructured":"Ghosh S, Dellibovi-Ragheb TA, Kerviel A, Pak E, Qiu Q, Fisher M et al (2020) beta-coronaviruses use lysosomes for egress instead of the biosynthetic secretory pathway. Cell 183(6):1520\u201335 e14. https:\/\/doi.org\/10.1016\/j.cell.2020.10.039","journal-title":"Cell"},{"key":"19_CR40","doi-asserted-by":"publisher","unstructured":"Hackstadt T, Chiramel AI, Hoyt FH, Williamson BN, Dooley CA, Beare PA et al (2021) Disruption of the Golgi apparatus and contribution of the endoplasmic reticulum to the SARS-CoV-2 replication complex. Viruses 13(9). https:\/\/doi.org\/10.3390\/v13091798","DOI":"10.3390\/v13091798"},{"key":"19_CR41","doi-asserted-by":"publisher","unstructured":"Matczuk AK, Zhang M, Veit M, Ugorski M (2022) Expression of the heterotrimeric GP2\/GP3\/GP4 spike of an arterivirus in mammalian cells. Viruses 14(4). https:\/\/doi.org\/10.3390\/v14040749","DOI":"10.3390\/v14040749"},{"issue":"2","key":"19_CR42","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.1128\/jvi.77.2.1368-1381.2003","volume":"77","author":"IJ Salanueva","year":"2003","unstructured":"Salanueva IJ, Novoa RR, Cabezas P, Lopez-Iglesias C, Carrascosa JL, Elliott RM et al (2003) Polymorphism and structural maturation of bunyamwera virus in Golgi and post-Golgi compartments. J Virol 77(2):1368\u20131381. https:\/\/doi.org\/10.1128\/jvi.77.2.1368-1381.2003","journal-title":"J Virol"},{"issue":"7","key":"19_CR43","doi-asserted-by":"publisher","first-page":"4525","DOI":"10.1128\/JVI.66.7.4525-4531.1992","volume":"66","author":"R Ronnholm","year":"1992","unstructured":"Ronnholm R (1992) Localization to the Golgi complex of Uukuniemi virus glycoproteins G1 and G2 expressed from cloned cDNAs. J Virol 66(7):4525\u20134531. https:\/\/doi.org\/10.1128\/JVI.66.7.4525-4531.1992","journal-title":"J Virol"},{"key":"19_CR44","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.563607","volume":"8","author":"P Lucin","year":"2020","unstructured":"Lucin P, Jug Vucko N, Karleusa L, Mahmutefendic Lucin H, Blagojevic Zagorac G, Lisnic B et al (2020) Cytomegalovirus generates assembly compartment in the early phase of infection by perturbation of host-cell factors recruitment at the early endosome\/endosomal recycling compartment\/trans-Golgi interface. Front Cell Dev Biol 8:563607. https:\/\/doi.org\/10.3389\/fcell.2020.563607","journal-title":"Front Cell Dev Biol"},{"issue":"3","key":"19_CR45","doi-asserted-by":"publisher","first-page":"663","DOI":"10.1128\/MMBR.00018-16","volume":"80","author":"TJ Gardner","year":"2016","unstructured":"Gardner TJ, Tortorella D (2016) Virion glycoprotein-mediated immune evasion by human cytomegalovirus: a sticky virus makes a slick getaway. Microbiol Mol Biol Rev 80(3):663\u2013677. https:\/\/doi.org\/10.1128\/MMBR.00018-16","journal-title":"Microbiol Mol Biol Rev"},{"issue":"6","key":"19_CR46","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1586\/14789450.2014.971116","volume":"11","author":"PM Jean Beltran","year":"2014","unstructured":"Jean Beltran PM, Cristea IM (2014) The life cycle and pathogenesis of human cytomegalovirus infection: lessons from proteomics. Expert Rev Proteomics 11(6):697\u2013711. https:\/\/doi.org\/10.1586\/14789450.2014.971116","journal-title":"Expert Rev Proteomics"},{"issue":"1","key":"19_CR47","doi-asserted-by":"publisher","first-page":"23489","DOI":"10.1038\/s41598-021-02929-1","volume":"11","author":"M Viettri","year":"2021","unstructured":"Viettri M, Zambrano JL, Rosales R, Caraballo GI, Gutierrez-Escolano AL, Ludert JE (2021) Flavivirus infections induce a Golgi stress response in vertebrate and mosquito cells. Sci Rep 11(1):23489. https:\/\/doi.org\/10.1038\/s41598-021-02929-1","journal-title":"Sci Rep"},{"issue":"17","key":"19_CR48","doi-asserted-by":"publisher","first-page":"E3462","DOI":"10.1073\/pnas.1616683114","volume":"114","author":"MD Hansen","year":"2017","unstructured":"Hansen MD, Johnsen IB, Stiberg KA, Sherstova T, Wakita T, Richard GM et al (2017) Hepatitis C virus triggers Golgi fragmentation and autophagy through the immunity-related GTPase M. Proc Natl Acad Sci USA 114(17):E3462\u2013E3E71. https:\/\/doi.org\/10.1073\/pnas.1616683114","journal-title":"Proc Natl Acad Sci USA"},{"issue":"2","key":"19_CR49","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/0042-6822(82)90092-7","volume":"119","author":"ME Dubois-Dalcq","year":"1982","unstructured":"Dubois-Dalcq ME, Doller EW, Haspel MV, Holmes KV (1982) Cell tropism and expression of mouse hepatitis viruses (MHV) in mouse spinal cord cultures. Virology 119(2):317\u2013331. https:\/\/doi.org\/10.1016\/0042-6822(82)90092-7","journal-title":"Virology"},{"key":"19_CR50","doi-asserted-by":"publisher","first-page":"139","DOI":"10.3389\/fcell.2019.00139","volume":"7","author":"JM Young","year":"2019","unstructured":"Young JM, Zine El Abidine A, Gomez-Martinez RA, Ozbun MA (2019) The known and potential intersections of Rab-GTPases in human papillomavirus infections. Front Cell Dev Biol 7:139. https:\/\/doi.org\/10.3389\/fcell.2019.00139","journal-title":"Front Cell Dev Biol"},{"issue":"2","key":"19_CR51","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.00054-22","volume":"13","author":"K King","year":"2022","unstructured":"King K, Larsen BB, Gryseels S, Richet C, Kraberger S, Jackson R et al (2022) Coevolutionary analysis implicates toll-like receptor 9 in papillomavirus restriction. MBio 13(2):e0005422. https:\/\/doi.org\/10.1128\/mbio.00054-22","journal-title":"MBio"},{"issue":"6","key":"19_CR52","doi-asserted-by":"publisher","first-page":"4679","DOI":"10.1128\/JVI.71.6.4679-4693.1997","volume":"71","author":"IV Sandoval","year":"1997","unstructured":"Sandoval IV, Carrasco L (1997) Poliovirus infection and expression of the poliovirus protein 2B provoke the disassembly of the Golgi complex, the organelle target for the antipoliovirus drug Ro-090179. J Virol 71(6):4679\u20134693. https:\/\/doi.org\/10.1128\/JVI.71.6.4679-4693.1997","journal-title":"J Virol"},{"issue":"2","key":"19_CR53","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.virol.2010.08.012","volume":"407","author":"CA Quiner","year":"2010","unstructured":"Quiner CA, Jackson WT (2010) Fragmentation of the Golgi apparatus provides replication membranes for human rhinovirus 1A. Virology 407(2):185\u2013195. https:\/\/doi.org\/10.1016\/j.virol.2010.08.012","journal-title":"Virology"},{"issue":"6","key":"19_CR54","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1111\/j.1600-0854.2010.01055.x","volume":"11","author":"D Tang","year":"2010","unstructured":"Tang D, Yuan H, Wang Y (2010) The role of GRASP65 in Golgi cisternal stacking and cell cycle progression. Traffic 11(6):827\u2013842. https:\/\/doi.org\/10.1111\/j.1600-0854.2010.01055.x","journal-title":"Traffic"},{"issue":"21","key":"19_CR55","doi-asserted-by":"publisher","first-page":"2833","DOI":"10.1091\/mbc.E17-02-0112","volume":"28","author":"ME Bekier 2nd","year":"2017","unstructured":"Bekier ME 2nd, Wang L, Li J, Huang H, Tang D, Zhang X et al (2017) Knockout of the Golgi stacking proteins GRASP55 and GRASP65 impairs Golgi structure and function. Mol Biol Cell 28(21):2833\u20132842. https:\/\/doi.org\/10.1091\/mbc.E17-02-0112","journal-title":"Mol Biol Cell"},{"issue":"2","key":"19_CR56","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/s0092-8674(00)80407-9","volume":"91","author":"FA Barr","year":"1997","unstructured":"Barr FA, Puype M, Vandekerckhove J, Warren G (1997) GRASP65, a protein involved in the stacking of Golgi cisternae. Cell 91(2):253\u2013262. https:\/\/doi.org\/10.1016\/s0092-8674(00)80407-9","journal-title":"Cell"},{"issue":"18","key":"19_CR57","doi-asserted-by":"publisher","first-page":"4949","DOI":"10.1093\/emboj\/18.18.4949","volume":"18","author":"J Shorter","year":"1999","unstructured":"Shorter J, Watson R, Giannakou ME, Clarke M, Warren G, Barr FA (1999) GRASP55, a second mammalian GRASP protein involved in the stacking of Golgi cisternae in a cell-free system. EMBO J 18(18):4949\u20134960. https:\/\/doi.org\/10.1093\/emboj\/18.18.4949","journal-title":"EMBO J"},{"issue":"13","key":"19_CR58","doi-asserted-by":"publisher","first-page":"3279","DOI":"10.1093\/emboj\/cdg317","volume":"22","author":"Y Wang","year":"2003","unstructured":"Wang Y, Seemann J, Pypaert M, Shorter J, Warren G (2003) A direct role for GRASP65 as a mitotically regulated Golgi stacking factor. EMBO J 22(13):3279\u20133290. https:\/\/doi.org\/10.1093\/emboj\/cdg317","journal-title":"EMBO J"},{"issue":"6","key":"19_CR59","doi-asserted-by":"publisher","first-page":"4921","DOI":"10.1074\/jbc.M412407200","volume":"280","author":"Y Wang","year":"2005","unstructured":"Wang Y, Satoh A, Warren G (2005) Mapping the functional domains of the Golgi stacking factor GRASP65. J Biol Chem 280(6):4921\u20134928. https:\/\/doi.org\/10.1074\/jbc.M412407200","journal-title":"J Biol Chem"},{"issue":"2","key":"19_CR60","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1083\/jcb.200907132","volume":"188","author":"Y Xiang","year":"2010","unstructured":"Xiang Y, Wang Y (2010) GRASP55 and GRASP65 play complementary and essential roles in Golgi cisternal stacking. J Cell Biol 188(2):237\u2013251. https:\/\/doi.org\/10.1083\/jcb.200907132","journal-title":"J Cell Biol"},{"issue":"2","key":"19_CR61","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0001647","volume":"3","author":"Y Wang","year":"2008","unstructured":"Wang Y, Wei JH, Bisel B, Tang D, Seemann J (2008) Golgi cisternal unstacking stimulates COPI vesicle budding and protein transport. PLoS One 3(2):e1647. https:\/\/doi.org\/10.1371\/journal.pone.0001647","journal-title":"PLoS One"},{"key":"19_CR62","doi-asserted-by":"publisher","first-page":"1659","DOI":"10.1038\/ncomms2669","volume":"4","author":"Y Xiang","year":"2013","unstructured":"Xiang Y, Zhang X, Nix DB, Katoh T, Aoki K, Tiemeyer M et al (2013) Regulation of protein glycosylation and sorting by the Golgi matrix proteins GRASP55\/65. Nat Commun 4:1659. https:\/\/doi.org\/10.1038\/ncomms2669","journal-title":"Nat Commun"},{"issue":"5","key":"19_CR63","doi-asserted-by":"publisher","first-page":"1849","DOI":"10.1073\/pnas.1323895111","volume":"111","author":"I Lee","year":"2014","unstructured":"Lee I, Tiwari N, Dunlop MH, Graham M, Liu X, Rothman JE (2014) Membrane adhesion dictates Golgi stacking and cisternal morphology. Proc Natl Acad Sci USA 111(5):1849\u20131854. https:\/\/doi.org\/10.1073\/pnas.1323895111","journal-title":"Proc Natl Acad Sci USA"},{"issue":"16","key":"19_CR64","doi-asserted-by":"publisher","first-page":"3183","DOI":"10.1016\/j.jmb.2016.02.030","volume":"428","author":"X Zhang","year":"2016","unstructured":"Zhang X, Wang Y (2016) Glycosylation quality control by the Golgi structure. J Mol Biol 428(16):3183\u20133193. https:\/\/doi.org\/10.1016\/j.jmb.2016.02.030","journal-title":"J Mol Biol"},{"issue":"4","key":"19_CR65","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1007\/s00018-022-04223-3","volume":"79","author":"E Ahat","year":"2022","unstructured":"Ahat E, Song Y, Xia K, Reid W, Li J, Bui S et al (2022) GRASP depletion-mediated Golgi fragmentation impairs glycosaminoglycan synthesis, sulfation, and secretion. Cell Mol Life Sci 79(4):199. https:\/\/doi.org\/10.1007\/s00018-022-04223-3","journal-title":"Cell Mol Life Sci"},{"issue":"4","key":"19_CR66","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.1016\/j.cell.2020.09.033","volume":"183","author":"TM Clausen","year":"2020","unstructured":"Clausen TM, Sandoval DR, Spliid CB, Pihl J, Perrett HR, Painter CD et al (2020) SARS-CoV-2 infection depends on cellular heparan sulfate and ACE2. Cell 183(4):1043\u201357 e15. https:\/\/doi.org\/10.1016\/j.cell.2020.09.033","journal-title":"Cell"},{"key":"19_CR67","doi-asserted-by":"publisher","first-page":"84","DOI":"10.3389\/fcell.2015.00084","volume":"3","author":"X Zhang","year":"2015","unstructured":"Zhang X, Wang Y (2015) GRASPs in Golgi structure and function. Front Cell Dev Biol 3:84. https:\/\/doi.org\/10.3389\/fcell.2015.00084","journal-title":"Front Cell Dev Biol"},{"issue":"12","key":"19_CR68","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1016\/j.tibs.2020.08.001","volume":"45","author":"X Zhang","year":"2020","unstructured":"Zhang X, Wang Y (2020) Nonredundant roles of GRASP55 and GRASP65 in the Golgi apparatus and beyond. Trends Biochem Sci 45(12):1065\u20131079. https:\/\/doi.org\/10.1016\/j.tibs.2020.08.001","journal-title":"Trends Biochem Sci"},{"issue":"4","key":"19_CR69","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.1073\/pnas.1220978110","volume":"110","author":"DA Thayer","year":"2013","unstructured":"Thayer DA, Jan YN, Jan LY (2013) Increased neuronal activity fragments the Golgi complex. Proc Natl Acad Sci USA 110(4):1482\u20131487. https:\/\/doi.org\/10.1073\/pnas.1220978110","journal-title":"Proc Natl Acad Sci USA"},{"key":"19_CR70","doi-asserted-by":"publisher","first-page":"1386149","DOI":"10.3389\/fcell.2024.1386149","volume":"12","author":"SR Akaaboune","year":"2024","unstructured":"Akaaboune SR, Wang Y (2024) Golgi defect as a major contributor to lysosomal dysfunction. Front Cell Dev Biol 12:1386149. https:\/\/doi.org\/10.3389\/fcell.2024.1386149","journal-title":"Front Cell Dev Biol"},{"key":"19_CR71","doi-asserted-by":"publisher","unstructured":"Akaaboune SR, Javed A, Bui S, Wierenga A, Wang Y (2025) GRASP55 regulates sorting and maturation of the lysosomal enzyme beta-hexosaminidase A. Mol Biol Cell:mbcE24100452. https:\/\/doi.org\/10.1091\/mbc.E24-10-0452","DOI":"10.1091\/mbc.E24-10-0452"},{"issue":"6","key":"19_CR72","doi-asserted-by":"publisher","first-page":"1052","DOI":"10.1016\/j.cell.2022.01.024","volume":"185","author":"M Zazhytska","year":"2022","unstructured":"Zazhytska M, Kodra A, Hoagland DA, Frere J, Fullard JF, Shayya H et al (2022) Non-cell-autonomous disruption of nuclear architecture as a potential cause of COVID-19-induced anosmia. Cell 185(6):1052\u201364 e12. https:\/\/doi.org\/10.1016\/j.cell.2022.01.024","journal-title":"Cell"},{"issue":"6","key":"19_CR73","doi-asserted-by":"publisher","first-page":"766","DOI":"10.1091\/mbc.E18-07-0462","volume":"30","author":"E Ahat","year":"2019","unstructured":"Ahat E, Xiang Y, Zhang X, Bekier ME 2nd, Wang Y (2019) GRASP depletion-mediated Golgi destruction decreases cell adhesion and migration via the reduction of alpha5beta1 integrin. Mol Biol Cell 30(6):766\u2013777. https:\/\/doi.org\/10.1091\/mbc.E18-07-0462","journal-title":"Mol Biol Cell"},{"issue":"2","key":"19_CR74","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1089\/rej.2011.1289","volume":"15","author":"G Accardi","year":"2012","unstructured":"Accardi G, Caruso C, Colonna-Romano G, Camarda C, Monastero R, Candore G (2012) Can Alzheimer disease be a form of type 3 diabetes? Rejuvenation Res 15(2):217\u2013221. https:\/\/doi.org\/10.1089\/rej.2011.1289","journal-title":"Rejuvenation Res"},{"issue":"3","key":"19_CR75","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1038\/nrneurol.2017.185","volume":"14","author":"SE Arnold","year":"2018","unstructured":"Arnold SE, Arvanitakis Z, Macauley-Rambach SL, Koenig AM, Wang HY, Ahima RS et al (2018) Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums. Nat Rev Neurol 14(3):168\u2013181. https:\/\/doi.org\/10.1038\/nrneurol.2017.185","journal-title":"Nat Rev Neurol"},{"key":"19_CR76","doi-asserted-by":"publisher","unstructured":"Franco KS, Bronson D (2005) Diabetes mellitus and Alzheimer disease. Arch Neurol 62(2):330; author reply \u22121. https:\/\/doi.org\/10.1001\/archneur.62.2.330-a","DOI":"10.1001\/archneur.62.2.330-a"},{"issue":"3","key":"19_CR77","doi-asserted-by":"publisher","first-page":"533","DOI":"10.2174\/18715273113126660167","volume":"13","author":"M Rasool","year":"2014","unstructured":"Rasool M, Malik A, Qazi AM, Sheikh IA, Manan A, Shaheen S et al (2014) Current view from Alzheimer disease to type 2 diabetes mellitus. CNS Neurol Disord Drug Targets 13(3):533\u2013542. https:\/\/doi.org\/10.2174\/18715273113126660167","journal-title":"CNS Neurol Disord Drug Targets"},{"issue":"29","key":"19_CR78","doi-asserted-by":"publisher","first-page":"30133","DOI":"10.1074\/jbc.M403773200","volume":"279","author":"NE Zachara","year":"2004","unstructured":"Zachara NE, O\u2019Donnell N, Cheung WD, Mercer JJ, Marth JD, Hart GW (2004) Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells. J Biol Chem 279(29):30133\u201330142. https:\/\/doi.org\/10.1074\/jbc.M403773200","journal-title":"J Biol Chem"},{"issue":"1","key":"19_CR79","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.neurobiolaging.2012.03.001","volume":"34","author":"C Kim","year":"2013","unstructured":"Kim C, Nam DW, Park SY, Song H, Hong HS, Boo JH et al (2013) O-linked beta-N-acetylglucosaminidase inhibitor attenuates beta-amyloid plaque and rescues memory impairment. Neurobiol Aging 34(1):275\u2013285. https:\/\/doi.org\/10.1016\/j.neurobiolaging.2012.03.001","journal-title":"Neurobiol Aging"},{"issue":"4","key":"19_CR80","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1038\/nchembio.797","volume":"8","author":"SA Yuzwa","year":"2012","unstructured":"Yuzwa SA, Shan X, Macauley MS, Clark T, Skorobogatko Y, Vosseller K et al (2012) Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation. Nat Chem Biol 8(4):393\u2013399. https:\/\/doi.org\/10.1038\/nchembio.797","journal-title":"Nat Chem Biol"},{"issue":"8","key":"19_CR81","doi-asserted-by":"publisher","first-page":"1736","DOI":"10.1016\/j.jmb.2014.01.004","volume":"426","author":"SA Yuzwa","year":"2014","unstructured":"Yuzwa SA, Cheung AH, Okon M, McIntosh LP, Vocadlo DJ (2014) O-GlcNAc modification of tau directly inhibits its aggregation without perturbing the conformational properties of tau monomers. J Mol Biol 426(8):1736\u20131752. https:\/\/doi.org\/10.1016\/j.jmb.2014.01.004","journal-title":"J Mol Biol"},{"key":"19_CR82","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/1750-1326-9-42","volume":"9","author":"SA Yuzwa","year":"2014","unstructured":"Yuzwa SA, Shan X, Jones BA, Zhao G, Woodward ML, Li X et al (2014) Pharmacological inhibition of O-GlcNAcase (OGA) prevents cognitive decline and amyloid plaque formation in bigenic tau\/APP mutant mice. Mol Neurodegener 9:42. https:\/\/doi.org\/10.1186\/1750-1326-9-42","journal-title":"Mol Neurodegener"},{"issue":"10","key":"19_CR83","doi-asserted-by":"publisher","first-page":"1787","DOI":"10.1080\/15548627.2019.1596480","volume":"15","author":"X Zhang","year":"2019","unstructured":"Zhang X, Wang L, Ireland SC, Ahat E, Li J, Bekier ME 2nd et al (2019) GORASP2\/GRASP55 collaborates with the PtdIns3K UVRAG complex to facilitate autophagosome-lysosome fusion. Autophagy 15(10):1787\u20131800. https:\/\/doi.org\/10.1080\/15548627.2019.1596480","journal-title":"Autophagy"},{"issue":"2","key":"19_CR84","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/j.devcel.2018.03.023","volume":"45","author":"X Zhang","year":"2018","unstructured":"Zhang X, Wang L, Lak B, Li J, Jokitalo E, Wang Y (2018) GRASP55 senses glucose deprivation through O-GlcNAcylation to promote autophagosome-lysosome fusion. Dev Cell 45(2):245\u201361 e6. https:\/\/doi.org\/10.1016\/j.devcel.2018.03.023","journal-title":"Dev Cell"},{"issue":"4","key":"19_CR85","doi-asserted-by":"publisher","DOI":"10.1080\/23723556.2018.1494948","volume":"5","author":"X Zhang","year":"2018","unstructured":"Zhang X, Wang Y (2018) GRASP55 facilitates autophagosome maturation under glucose deprivation. Mol Cell Oncol 5(4):e1494948. https:\/\/doi.org\/10.1080\/23723556.2018.1494948","journal-title":"Mol Cell Oncol"},{"issue":"9","key":"19_CR86","doi-asserted-by":"publisher","first-page":"1649","DOI":"10.1080\/15548627.2018.1491214","volume":"14","author":"X Zhang","year":"2018","unstructured":"Zhang X, Wang Y (2018) The Golgi stacking protein GORASP2\/GRASP55 serves as an energy sensor to promote autophagosome maturation under glucose starvation. Autophagy 14(9):1649\u20131651. https:\/\/doi.org\/10.1080\/15548627.2018.1491214","journal-title":"Autophagy"},{"issue":"7","key":"19_CR87","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1038\/ncb1426","volume":"8","author":"C Liang","year":"2006","unstructured":"Liang C, Feng P, Ku B, Dotan I, Canaani D, Oh BH et al (2006) Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG. Nat Cell Biol 8(7):688\u2013699. https:\/\/doi.org\/10.1038\/ncb1426","journal-title":"Nat Cell Biol"},{"issue":"8","key":"19_CR88","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2022.102219","volume":"298","author":"E Ahat","year":"2022","unstructured":"Ahat E, Bui S, Zhang J, da Veiga Leprevost F, Sharkey L, Reid W et al (2022) GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin. J Biol Chem 298(8):102219. https:\/\/doi.org\/10.1016\/j.jbc.2022.102219","journal-title":"J Biol Chem"},{"issue":"33","key":"19_CR89","doi-asserted-by":"publisher","first-page":"E3138","DOI":"10.1073\/pnas.1301440110","volume":"110","author":"BB Holmes","year":"2013","unstructured":"Holmes BB, DeVos SL, Kfoury N, Li M, Jacks R, Yanamandra K et al (2013) Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds. Proc Natl Acad Sci USA 110(33):E3138\u2013E3147. https:\/\/doi.org\/10.1073\/pnas.1301440110","journal-title":"Proc Natl Acad Sci USA"},{"issue":"5","key":"19_CR90","doi-asserted-by":"publisher","first-page":"1818","DOI":"10.1002\/anie.201913029","volume":"59","author":"J Zhao","year":"2020","unstructured":"Zhao J, Zhu Y, Song X, Xiao Y, Su G, Liu X et al (2020) 3-O-sulfation of heparan sulfate enhances tau interaction and cellular uptake. Angew Chem Int Ed Engl 59(5):1818\u20131827. https:\/\/doi.org\/10.1002\/anie.201913029","journal-title":"Angew Chem Int Ed Engl"},{"issue":"1","key":"19_CR91","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1186\/s13195-021-00850-3","volume":"13","author":"Y Zhou","year":"2021","unstructured":"Zhou Y, Xu J, Hou Y, Leverenz JB, Kallianpur A, Mehra R et al (2021) Network medicine links SARS-CoV-2\/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment. Alzheimer\u2019s Res Ther 13(1):110. https:\/\/doi.org\/10.1186\/s13195-021-00850-3","journal-title":"Alzheimer\u2019s Res Ther"},{"issue":"6","key":"19_CR92","doi-asserted-by":"publisher","first-page":"2485","DOI":"10.1007\/s00018-020-03711-8","volume":"78","author":"E Michiels","year":"2021","unstructured":"Michiels E, Rousseau F, Schymkowitz J (2021) Mechanisms and therapeutic potential of interactions between human amyloids and viruses. Cell Mol Life Sci 78(6):2485\u20132501","journal-title":"Cell Mol Life Sci"},{"issue":"1","key":"19_CR93","doi-asserted-by":"publisher","first-page":"5739","DOI":"10.1038\/s41467-021-25855-2","volume":"12","author":"S Liu","year":"2021","unstructured":"Liu S, Hossinger A, Heumuller SE, Hornberger A, Buravlova O, Konstantoulea K et al (2021) Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions. Nat Commun 12(1):5739. https:\/\/doi.org\/10.1038\/s41467-021-25855-2","journal-title":"Nat Commun"},{"issue":"1","key":"19_CR94","doi-asserted-by":"publisher","first-page":"10109","DOI":"10.1038\/s41598-021-89586-6","volume":"11","author":"H Hara","year":"2021","unstructured":"Hara H, Chida J, Uchiyama K, Pasiana AD, Takahashi E, Kido H et al (2021) Neurotropic influenza A virus infection causes prion protein misfolding into infectious prions in neuroblastoma cells. Sci Rep 11(1):10109. https:\/\/doi.org\/10.1038\/s41598-021-89586-6","journal-title":"Sci Rep"},{"issue":"11","key":"19_CR95","doi-asserted-by":"publisher","first-page":"1141","DOI":"10.1093\/jnen\/nlaa109","volume":"79","author":"DM Asher","year":"2020","unstructured":"Asher DM, Belay E, Bigio E, Brandner S, Brubaker SA, Caughey B et al (2020) Risk of transmissibility from neurodegenerative disease-associated proteins: experimental knowns and unknowns. J Neuropathol Exp Neurol 79(11):1141\u20131146. https:\/\/doi.org\/10.1093\/jnen\/nlaa109","journal-title":"J Neuropathol Exp Neurol"},{"issue":"20","key":"19_CR96","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2020106230","volume":"39","author":"A Ramani","year":"2020","unstructured":"Ramani A, Muller L, Ostermann PN, Gabriel E, Abida-Islam P, Muller-Schiffmann A et al (2020) SARS-CoV-2 targets neurons of 3D human brain organoids. EMBO J 39(20):e106230. https:\/\/doi.org\/10.15252\/embj.2020106230","journal-title":"EMBO J"},{"issue":"1","key":"19_CR97","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1021\/acschemneuro.1c00666","volume":"13","author":"SA Semerdzhiev","year":"2022","unstructured":"Semerdzhiev SA, Fakhree MAA, Segers-Nolten I, Blum C, Claessens M (2022) Interactions between SARS-CoV-2 N-protein and alpha-synuclein accelerate amyloid formation. ACS Chem Neurosci 13(1):143\u2013150. https:\/\/doi.org\/10.1021\/acschemneuro.1c00666","journal-title":"ACS Chem Neurosci"},{"issue":"8","key":"19_CR98","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1007\/s13238-022-00905-7","volume":"13","author":"Y Li","year":"2022","unstructured":"Li Y, Lu S, Gu J, Xia W, Zhang S, Zhang S et al (2022) SARS-CoV-2 impairs the disassembly of stress granules and promotes ALS-associated amyloid aggregation. Protein Cell 13(8):602\u2013614. https:\/\/doi.org\/10.1007\/s13238-022-00905-7","journal-title":"Protein Cell"},{"issue":"1","key":"19_CR99","doi-asserted-by":"publisher","first-page":"3387","DOI":"10.1038\/s41467-022-30932-1","volume":"13","author":"M Charnley","year":"2022","unstructured":"Charnley M, Islam S, Bindra GK, Engwirda J, Ratcliffe J, Zhou J et al (2022) Neurotoxic amyloidogenic peptides in the proteome of SARS-COV2: potential implications for neurological symptoms in COVID-19. Nat Commun 13(1):3387. https:\/\/doi.org\/10.1038\/s41467-022-30932-1","journal-title":"Nat Commun"},{"issue":"1","key":"19_CR100","doi-asserted-by":"publisher","first-page":"1567","DOI":"10.1038\/s41598-018-38146-6","volume":"9","author":"AM van Ziel","year":"2019","unstructured":"van Ziel AM, Largo-Barrientos P, Wolzak K, Verhage M, Scheper W (2019) Unconventional secretion factor GRASP55 is increased by pharmacological unfolded protein response inducers in neurons. Sci Rep 9(1):1567. https:\/\/doi.org\/10.1038\/s41598-018-38146-6","journal-title":"Sci Rep"},{"issue":"1","key":"19_CR101","doi-asserted-by":"publisher","first-page":"3942","DOI":"10.1038\/s41467-020-17405-z","volume":"11","author":"ND Beckmann","year":"2020","unstructured":"Beckmann ND, Lin WJ, Wang M, Cohain AT, Charney AW, Wang P et al (2020) Multiscale causal networks identify VGF as a key regulator of Alzheimer\u2019s disease. Nat Commun 11(1):3942. https:\/\/doi.org\/10.1038\/s41467-020-17405-z","journal-title":"Nat Commun"},{"key":"19_CR102","doi-asserted-by":"publisher","unstructured":"Shen WB, Logue J, Yang P, Baracco L, Elahi M, Reece EA et al (2022) SARS-CoV-2 invades cognitive centers of the brain and induces Alzheimer\u2019s-like neuropathology. bioRxiv: The Preprint Server for Biology. https:\/\/doi.org\/10.1101\/2022.01.31.478476","DOI":"10.1101\/2022.01.31.478476"},{"issue":"7734","key":"19_CR103","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1038\/s41586-018-0761-3","volume":"564","author":"J Chen","year":"2018","unstructured":"Chen J, Chen ZJ (2018) PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation. Nature 564(7734):71\u201376. https:\/\/doi.org\/10.1038\/s41586-018-0761-3","journal-title":"Nature"},{"issue":"5","key":"19_CR104","doi-asserted-by":"publisher","first-page":"363","DOI":"10.3892\/etm.2022.11290","volume":"23","author":"V Efstathiou","year":"2022","unstructured":"Efstathiou V, Stefanou MI, Demetriou M, Siafakas N, Makris M, Tsivgoulis G et al (2022) Long COVID and neuropsychiatric manifestations (Review). Exp Ther Med 23(5):363. https:\/\/doi.org\/10.3892\/etm.2022.11290","journal-title":"Exp Ther Med"},{"issue":"7","key":"19_CR105","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1001\/jamapsychiatry.2022.1067","volume":"79","author":"AK Clift","year":"2022","unstructured":"Clift AK, Ranger TA, Patone M, Coupland CAC, Hatch R, Thomas K et al (2022) Neuropsychiatric ramifications of severe COVID-19 and other severe acute respiratory infections. JAMA Psychiatry 79(7):690\u2013698. https:\/\/doi.org\/10.1001\/jamapsychiatry.2022.1067","journal-title":"JAMA Psychiatry"},{"key":"19_CR106","doi-asserted-by":"publisher","unstructured":"Frontera JA, Simon NM (2022) Bridging knowledge gaps in the diagnosis and management of neuropsychiatric sequelae of COVID-19. JAMA Psychiatry. https:\/\/doi.org\/10.1001\/jamapsychiatry.2022.1616","DOI":"10.1001\/jamapsychiatry.2022.1616"},{"key":"19_CR107","doi-asserted-by":"publisher","unstructured":"Frere JJ, Serafini RA, Pryce KD, Zazhytska M, Oishi K, Golynker I et al (2022) SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations post recovery. Sci Transl Med:eabq3059. https:\/\/doi.org\/10.1126\/scitranslmed.abq3059","DOI":"10.1126\/scitranslmed.abq3059"},{"key":"19_CR108","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.730088","volume":"12","author":"L Francistiova","year":"2021","unstructured":"Francistiova L, Klepe A, Curley G, Gulya K, Dinnyes A, Filkor K (2021) Cellular and molecular effects of SARS-CoV-2 linking lung infection to the brain. Front Immunol 12:730088. https:\/\/doi.org\/10.3389\/fimmu.2021.730088","journal-title":"Front Immunol"},{"issue":"7","key":"19_CR109","doi-asserted-by":"publisher","first-page":"2555","DOI":"10.1093\/brain\/awac151","volume":"145","author":"MH Lee","year":"2022","unstructured":"Lee MH, Perl DP, Steiner J, Pasternack N, Li W, Maric D et al (2022) Neurovascular injury with complement activation and inflammation in COVID-19. Brain 145(7):2555\u20132568. https:\/\/doi.org\/10.1093\/brain\/awac151","journal-title":"Brain"},{"issue":"9","key":"19_CR110","doi-asserted-by":"publisher","first-page":"1764","DOI":"10.1111\/ene.14277","volume":"27","author":"S Natoli","year":"2020","unstructured":"Natoli S, Oliveira V, Calabresi P, Maia LF, Pisani A (2020) Does SARS-Cov-2 invade the brain? Translational lessons from animal models. Eur J Neurol 27(9):1764\u20131773. https:\/\/doi.org\/10.1111\/ene.14277","journal-title":"Eur J Neurol"},{"key":"19_CR111","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2021.674123","volume":"15","author":"K Bilinska","year":"2021","unstructured":"Bilinska K, von Bartheld CS, Butowt R (2021) Expression of the ACE2 virus entry protein in the nervus terminalis reveals the potential for an alternative route to brain infection in COVID-19. Front Cell Neurosci 15:674123. https:\/\/doi.org\/10.3389\/fncel.2021.674123","journal-title":"Front Cell Neurosci"},{"issue":"1","key":"19_CR112","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s13024-022-00529-9","volume":"17","author":"R Butowt","year":"2022","unstructured":"Butowt R, von Bartheld CS (2022) The route of SARS-CoV-2 to brain infection: have we been barking up the wrong tree? Mol Neurodegener 17(1):20. https:\/\/doi.org\/10.1186\/s13024-022-00529-9","journal-title":"Mol Neurodegener"},{"issue":"2","key":"19_CR113","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1038\/s41593-020-00758-5","volume":"24","author":"J Meinhardt","year":"2021","unstructured":"Meinhardt J, Radke J, Dittmayer C, Franz J, Thomas C, Mothes R et al (2021) Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19. Nat Neurosci 24(2):168\u2013175. https:\/\/doi.org\/10.1038\/s41593-020-00758-5","journal-title":"Nat Neurosci"},{"issue":"7907","key":"19_CR114","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1038\/s41586-022-04569-5","volume":"604","author":"G Douaud","year":"2022","unstructured":"Douaud G, Lee S, Alfaro-Almagro F, Arthofer C, Wang C, McCarthy P et al (2022) SARS-CoV-2 is associated with changes in brain structure in UK Biobank. Nature 604(7907):697\u2013707. https:\/\/doi.org\/10.1038\/s41586-022-04569-5","journal-title":"Nature"},{"issue":"1","key":"19_CR115","doi-asserted-by":"publisher","first-page":"1745","DOI":"10.1038\/s41467-022-29440-z","volume":"13","author":"I Rutkai","year":"2022","unstructured":"Rutkai I, Mayer MG, Hellmers LM, Ning B, Huang Z, Monjure CJ et al (2022) Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates. Nat Commun 13(1):1745. https:\/\/doi.org\/10.1038\/s41467-022-29440-z","journal-title":"Nat Commun"},{"issue":"6","key":"19_CR116","doi-asserted-by":"publisher","first-page":"1685","DOI":"10.1111\/ene.15307","volume":"29","author":"V Rass","year":"2022","unstructured":"Rass V, Beer R, Schiefecker AJ, Lindner A, Kofler M, Ianosi BA et al (2022) Neurological outcomes 1 year after COVID-19 diagnosis: a prospective longitudinal cohort study. Eur J Neurol 29(6):1685\u20131696. https:\/\/doi.org\/10.1111\/ene.15307","journal-title":"Eur J Neurol"},{"issue":"2","key":"19_CR117","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1002\/acn3.51498","volume":"9","author":"AC Apple","year":"2022","unstructured":"Apple AC, Oddi A, Peluso MJ, Asken BM, Henrich TJ, Kelly JD et al (2022) Risk factors and abnormal cerebrospinal fluid associate with cognitive symptoms after mild COVID-19. Ann Clin Transl Neurol 9(2):221\u2013226. https:\/\/doi.org\/10.1002\/acn3.51498","journal-title":"Ann Clin Transl Neurol"},{"issue":"7862","key":"19_CR118","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1038\/s41586-021-03553-9","volume":"594","author":"Z Al-Aly","year":"2021","unstructured":"Al-Aly Z, Xie Y, Bowe B (2021) High-dimensional characterization of post-acute sequelae of COVID-19. Nature 594(7862):259\u2013264. https:\/\/doi.org\/10.1038\/s41586-021-03553-9","journal-title":"Nature"},{"key":"19_CR119","doi-asserted-by":"publisher","DOI":"10.1136\/bmj-2021-068993","volume":"376","author":"Y Xie","year":"2022","unstructured":"Xie Y, Xu E, Al-Aly Z (2022) Risks of mental health outcomes in people with covid-19: cohort study. BMJ 376:e068993. https:\/\/doi.org\/10.1136\/bmj-2021-068993","journal-title":"BMJ"},{"issue":"2","key":"19_CR120","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1007\/s12028-021-01359-1","volume":"36","author":"L Gurin","year":"2022","unstructured":"Gurin L, Evangelist M, Laverty P, Hanley K, Corcoran J, Herbsman J et al (2022) Early neurorehabilitation and recovery from disorders of consciousness after severe COVID-19. Neurocrit Care 36(2):357\u2013371. https:\/\/doi.org\/10.1007\/s12028-021-01359-1","journal-title":"Neurocrit Care"},{"issue":"10343","key":"19_CR121","doi-asserted-by":"publisher","first-page":"2263","DOI":"10.1016\/S0140-6736(22)00941-2","volume":"399","author":"M Antonelli","year":"2022","unstructured":"Antonelli M, Capdevila Pujol J, Spector T, Ourselin S, Steves C (2022) Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2. Lancet 399(10343):2263\u20132264","journal-title":"Lancet"},{"issue":"14","key":"19_CR122","doi-asserted-by":"publisher","first-page":"2452","DOI":"10.1016\/j.cell.2022.06.008","volume":"185","author":"A Fernandez-Castaneda","year":"2022","unstructured":"Fernandez-Castaneda A, Lu P, Geraghty AC, Song E, Lee MH, Wood J et al (2022) Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation. Cell 185(14):2452\u201368 e16. https:\/\/doi.org\/10.1016\/j.cell.2022.06.008","journal-title":"Cell"},{"issue":"14","key":"19_CR123","doi-asserted-by":"publisher","first-page":"2391","DOI":"10.1016\/j.cell.2022.06.020","volume":"185","author":"J Kao","year":"2022","unstructured":"Kao J, Frankland PW (2022) COVID fog demystified. Cell 185(14):2391\u20132393. https:\/\/doi.org\/10.1016\/j.cell.2022.06.020","journal-title":"Cell"},{"issue":"6","key":"19_CR124","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1001\/jamaneurol.2022.0154","volume":"79","author":"CY Ho","year":"2022","unstructured":"Ho CY, Salimian M, Hegert J, O\u2019Brien J, Choi SG, Ames H et al (2022) Postmortem assessment of olfactory tissue degeneration and microvasculopathy in patients with COVID-19. JAMA Neurol 79(6):544\u2013553. https:\/\/doi.org\/10.1001\/jamaneurol.2022.0154","journal-title":"JAMA Neurol"},{"issue":"14","key":"19_CR125","doi-asserted-by":"publisher","first-page":"3771","DOI":"10.1021\/acs.jpcb.8b00139","volume":"122","author":"M Vahed","year":"2018","unstructured":"Vahed M, Neya S, Matsuzaki K, Hoshino T (2018) Analysis of physicochemical interaction of Abeta(40) with a GM1 ganglioside-containing lipid membrane. J Phys Chem B 122(14):3771\u20133781. https:\/\/doi.org\/10.1021\/acs.jpcb.8b00139","journal-title":"J Phys Chem B"},{"issue":"10","key":"19_CR126","doi-asserted-by":"publisher","first-page":"1062","DOI":"10.1038\/nm1095-1062","volume":"1","author":"K Yanagisawa","year":"1995","unstructured":"Yanagisawa K, Odaka A, Suzuki N, Ihara Y (1995) GM1 ganglioside-bound amyloid beta-protein (A beta): a possible form of preamyloid in Alzheimer\u2019s disease. Nat Med 1(10):1062\u20131066. https:\/\/doi.org\/10.1038\/nm1095-1062","journal-title":"Nat Med"},{"issue":"1","key":"19_CR127","doi-asserted-by":"publisher","first-page":"14232","DOI":"10.1038\/s41598-021-93857-7","volume":"11","author":"AH Janneh","year":"2021","unstructured":"Janneh AH, Kassir MF, Dwyer CJ, Chakraborty P, Pierce JS, Flume PA et al (2021) Alterations of lipid metabolism provide serologic biomarkers for the detection of asymptomatic versus symptomatic COVID-19 patients. Sci Rep 11(1):14232. https:\/\/doi.org\/10.1038\/s41598-021-93857-7","journal-title":"Sci Rep"},{"key":"19_CR128","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.neuropharm.2018.07.007","volume":"139","author":"J Wen","year":"2018","unstructured":"Wen J, Maxwell RR, Wolf AJ, Spira M, Gulinello ME, Cole PD (2018) Methotrexate causes persistent deficits in memory and executive function in a juvenile animal model. Neuropharmacology 139:76\u201384. https:\/\/doi.org\/10.1016\/j.neuropharm.2018.07.007","journal-title":"Neuropharmacology"},{"key":"19_CR129","doi-asserted-by":"publisher","unstructured":"Kozminski P, Halik PK, Chesori R, Gniazdowska E (2020) Overview of dual-acting drug methotrexate in different neurological diseases, autoimmune pathologies and cancers. Int J Mol Sci 21(10). https:\/\/doi.org\/10.3390\/ijms21103483","DOI":"10.3390\/ijms21103483"},{"key":"19_CR130","doi-asserted-by":"publisher","unstructured":"Alper HE, Tuly RA, Seil K, Brite J (2020) Post-9\/11 mental health comorbidity predicts self-reported confusion or memory loss in world trade center health registry enrollees. Int J Environ Res Public Health 17(19). https:\/\/doi.org\/10.3390\/ijerph17197330","DOI":"10.3390\/ijerph17197330"},{"issue":"1","key":"19_CR131","doi-asserted-by":"publisher","DOI":"10.1002\/dad2.12154","volume":"13","author":"PF Kuan","year":"2021","unstructured":"Kuan PF, Clouston S, Yang X, Che C, Gandy S, Kotov R et al (2021) Single-cell transcriptomics analysis of mild cognitive impairment in World Trade Center disaster responders. Alzheimers Dement (Amst) 13(1):e12154. https:\/\/doi.org\/10.1002\/dad2.12154","journal-title":"Alzheimers Dement (Amst)"},{"key":"19_CR132","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.dadm.2016.08.001","volume":"4","author":"SA Clouston","year":"2016","unstructured":"Clouston SA, Kotov R, Pietrzak RH, Luft BJ, Gonzalez A, Richards M et al (2016) Cognitive impairment among World Trade Center responders: long-term implications of re-experiencing the 9\/11 terrorist attacks. Alzheimers Dement (Amst) 4:67\u201375. https:\/\/doi.org\/10.1016\/j.dadm.2016.08.001","journal-title":"Alzheimers Dement (Amst)"},{"issue":"2","key":"19_CR133","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1038\/s41582-021-00576-8","volume":"18","author":"SAP Clouston","year":"2022","unstructured":"Clouston SAP, Hall CB, Kritikos M, Bennett DA, DeKosky S, Edwards J et al (2022) Cognitive impairment and World Trade Centre-related exposures. Nat Rev Neurol 18(2):103\u2013116. https:\/\/doi.org\/10.1038\/s41582-021-00576-8","journal-title":"Nat Rev Neurol"},{"key":"19_CR134","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n156","volume":"372","author":"SF Ackley","year":"2021","unstructured":"Ackley SF, Zimmerman SC, Brenowitz WD, Tchetgen Tchetgen EJ, Gold AL, Manly JJ et al (2021) Effect of reductions in amyloid levels on cognitive change in randomized trials: instrumental variable meta-analysis. BMJ 372:n156. https:\/\/doi.org\/10.1136\/bmj.n156","journal-title":"BMJ"},{"issue":"2","key":"19_CR135","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1002\/ana.22052","volume":"68","author":"S Gandy","year":"2010","unstructured":"Gandy S, Simon AJ, Steele JW, Lublin AL, Lah JJ, Walker LC et al (2010) Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers. Ann Neurol 68(2):220\u2013230. https:\/\/doi.org\/10.1002\/ana.22052","journal-title":"Ann Neurol"},{"issue":"12","key":"19_CR136","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1016\/j.tibs.2020.08.001","volume":"45","author":"X Zhang","year":"2020","unstructured":"Zhang X, Wang Y (2020) Non-redundant roles of GRASP55 and GRASP65 in the Golgi apparatus and beyond. Trends Biochem Sci 45(12):1065\u20131079","journal-title":"Trends Biochem Sci"}],"container-title":["Subcellular Biochemistry","The Golgi Network, Volume II"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-032-16833-7_19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T10:36:13Z","timestamp":1771583773000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-032-16833-7_19"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"ISBN":["9783032168320","9783032168337"],"references-count":136,"URL":"https:\/\/doi.org\/10.1007\/978-3-032-16833-7_19","relation":{},"ISSN":["0306-0225","2542-8810"],"issn-type":[{"value":"0306-0225","type":"print"},{"value":"2542-8810","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"21 February 2026","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}