{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T18:45:37Z","timestamp":1772822737303,"version":"3.50.1"},"publisher-location":"Cham","reference-count":22,"publisher":"Springer Nature Switzerland","isbn-type":[{"value":"9783032168474","type":"print"},{"value":"9783032168481","type":"electronic"}],"license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026]]},"DOI":"10.1007\/978-3-032-16848-1_4","type":"book-chapter","created":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T13:07:59Z","timestamp":1772802479000},"page":"48-62","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["An Efficient Feature Extraction Method for\u00a0Identifying Signatures of\u00a0Viral Genomic Variants"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-1040-4642","authenticated-orcid":false,"given":"Felipe Bueno","family":"de Souza","sequence":"first","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0698-6360","authenticated-orcid":false,"given":"Matheus Henrique","family":"Pimenta-Zanon","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7530-682X","authenticated-orcid":false,"given":"Dora","family":"Henriques","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9663-8399","authenticated-orcid":false,"given":"M. Alice","family":"Pinto","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2431-8665","authenticated-orcid":false,"given":"Carlos","family":"Balsa","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1344-8264","authenticated-orcid":false,"given":"Jos\u00e9","family":"Rufino","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8786-3313","authenticated-orcid":false,"given":"Fabricio Martins","family":"Lopes","sequence":"additional","affiliation":[]}],"member":"297","published-online":{"date-parts":[[2026,4,1]]},"reference":[{"issue":"18","key":"4_CR1","doi-asserted-by":"publisher","first-page":"2834","DOI":"10.1093\/bioinformatics\/btab203","volume":"37","author":"TL Bailey","year":"2021","unstructured":"Bailey, T.L.: Streme: accurate and versatile sequence motif discovery. Bioinformatics 37(18), 2834\u20132840 (2021)","journal-title":"Bioinformatics"},{"key":"4_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1471-2105-11-179","volume":"11","author":"TL Bailey","year":"2010","unstructured":"Bailey, T.L., Bod\u00e9n, M., Whitington, T., Machanick, P.: The value of position-specific priors in motif discovery using meme. BMC Bioinf. 11, 1\u201314 (2010)","journal-title":"BMC Bioinf."},{"issue":"W1","key":"4_CR3","doi-asserted-by":"publisher","first-page":"W39","DOI":"10.1093\/nar\/gkv416","volume":"43","author":"TL Bailey","year":"2015","unstructured":"Bailey, T.L., Johnson, J., Grant, C.E., Noble, W.S.: The meme suite. Nucleic Acids Res. 43(W1), W39\u2013W49 (2015)","journal-title":"Nucleic Acids Res."},{"issue":"11","key":"4_CR4","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1089\/cmb.2017.0042","volume":"24","author":"GA Barros-Carvalho","year":"2017","unstructured":"Barros-Carvalho, G.A., Van Sluys, M.A., Lopes, F.M.: An efficient approach to explore and discriminate anomalous regions in bacterial genomes based on maximum entropy. J. Comput. Biol. 24(11), 1125\u20131133 (2017)","journal-title":"J. Comput. Biol."},{"issue":"1","key":"4_CR5","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1137\/141000671","volume":"59","author":"J Bezanson","year":"2017","unstructured":"Bezanson, J., Edelman, A., Karpinski, S., Shah, V.B.: Julia: a fresh approach to numerical computing. SIAM Rev. 59(1), 65\u201398 (2017)","journal-title":"SIAM Rev."},{"key":"4_CR6","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1007\/978-3-030-65775-8_18","volume-title":"Advances in Bioinformatics and Computational Biology","author":"MM Breve","year":"2020","unstructured":"Breve, M.M., Lopes, F.M.: A simplified complex network-based approach to mrna and ncrna transcript classification. In: Setubal, J.C., Silva, W.M. (eds.) Advances in Bioinformatics and Computational Biology, pp. 192\u2013203. Springer International Publishing, Cham (2020)"},{"key":"4_CR7","unstructured":"Breve, M.M., Pimenta-Zanon, M.H., Lopes, F.M.: Basinetentropy: an alignment-free method for classification of biological sequences through complex networks and entropy maximization (2022)"},{"issue":"4","key":"4_CR8","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1038\/nrg2323","volume":"9","author":"S Duffy","year":"2008","unstructured":"Duffy, S., Shackelton, L.A., Holmes, E.C.: Rates of evolutionary change in viruses: patterns and determinants. Nat. Rev. Genet. 9(4), 267\u2013276 (2008)","journal-title":"Nat. Rev. Genet."},{"issue":"D1","key":"4_CR9","doi-asserted-by":"publisher","first-page":"D701","DOI":"10.1093\/nar\/gkad958","volume":"52","author":"Y Feng","year":"2024","unstructured":"Feng, Y., Yi, J., Yang, L., Wang, Y., Wen, J., Zhao, W., Kim, P., Zhou, X.: Cov2var, a function annotation database of sars-cov-2 genetic variation. Nucleic Acids Res. 52(D1), D701\u2013D713 (2024)","journal-title":"Nucleic Acids Res."},{"issue":"6","key":"4_CR10","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1038\/nrg.2016.49","volume":"17","author":"S Goodwin","year":"2016","unstructured":"Goodwin, S., McPherson, J.D., McCombie, W.R.: Coming of age: ten years of next-generation sequencing technologies. Nat. Rev. Genet. 17(6), 333\u2013351 (2016)","journal-title":"Nat. Rev. Genet."},{"issue":"3","key":"4_CR11","doi-asserted-by":"publisher","first-page":"1829","DOI":"10.1109\/TCBB.2022.3218588","volume":"20","author":"MR de Holanda Maia","year":"2022","unstructured":"de Holanda Maia, M.R., Plastino, A., Freitas, A., de Magalhaes, J.P.: Interpretable ensembles of classifiers for uncertain data with bioinformatics applications. IEEE\/ACM Trans. Comput. Biol. Bioinf. 20(3), 1829\u20131841 (2022)","journal-title":"IEEE\/ACM Trans. Comput. Biol. Bioinf."},{"key":"4_CR12","doi-asserted-by":"publisher","first-page":"1516","DOI":"10.1016\/j.procs.2023.01.130","volume":"218","author":"N Iqbal","year":"2023","unstructured":"Iqbal, N., Kumar, P.: From data science to bioscience: emerging era of bioinformatics applications, tools and challenges. Procedia Comput. Sci. 218, 1516\u20131528 (2023)","journal-title":"Procedia Comput. Sci."},{"key":"4_CR13","unstructured":"Kaplan, D.: Bayesian Statistics for the Social Sciences. Guilford Publications (2023)"},{"key":"4_CR14","doi-asserted-by":"publisher","unstructured":"Karim, M.R., et al.: Explainable AI for bioinformatics: methods, tools and applications. Briefings Bioinf. 24(5), bbad236 (2023). https:\/\/doi.org\/10.1093\/bib\/bbad236","DOI":"10.1093\/bib\/bbad236"},{"issue":"1","key":"4_CR15","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1186\/s12859-024-05917-0","volume":"25","author":"S Khan","year":"2024","unstructured":"Khan, S., AlQahtani, S.A., Noor, S., Ahmad, N.: Pssm-sumo: deep learning based intelligent model for prediction of sumoylation sites using discriminative features. BMC Bioinf. 25(1), 284 (2024)","journal-title":"BMC Bioinf."},{"key":"4_CR16","unstructured":"Koutroumbas, K., Theodoridis, S.: Pattern Recognition. Academic Press (2008)"},{"issue":"6","key":"4_CR17","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1089\/cmb.2018.0239","volume":"26","author":"D Lebatteux","year":"2019","unstructured":"Lebatteux, D., Remita, A.M., Diallo, A.B.: Toward an alignment-free method for feature extraction and accurate classification of viral sequences. J. Comput. Biol. 26(6), 519\u2013535 (2019)","journal-title":"J. Comput. Biol."},{"issue":"1","key":"4_CR18","doi-asserted-by":"publisher","first-page":"e0296627","DOI":"10.1371\/journal.pone.0296627","volume":"19","author":"D Lebatteux","year":"2024","unstructured":"Lebatteux, D., Soudeyns, H., Boucoiran, I., Gantt, S., Diallo, A.B.: Machine learning-based approach kevolve efficiently identifies sars-cov-2 variant-specific genomic signatures. PLoS ONE 19(1), e0296627 (2024)","journal-title":"PLoS ONE"},{"issue":"1","key":"4_CR19","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1186\/s12859-025-06037-z","volume":"26","author":"MH Pimenta-Zanon","year":"2025","unstructured":"Pimenta-Zanon, M.H., Kashiwabara, A.Y., Vanzela, A.L.L., Lopes, F.M.: Gramep: an alignment-free method based on the maximum entropy principle for identifying snps. BMC Bioinf. 26(1), 66 (2025)","journal-title":"BMC Bioinf."},{"issue":"1","key":"4_CR20","doi-asserted-by":"publisher","first-page":"3","DOI":"10.2166\/hydro.2008.015","volume":"10","author":"DP Solomatine","year":"2008","unstructured":"Solomatine, D.P., Ostfeld, A.: Data-driven modelling: some past experiences and new approaches. J. Hydroinf. 10(1), 3\u201322 (2008)","journal-title":"J. Hydroinf."},{"key":"4_CR21","doi-asserted-by":"crossref","unstructured":"Villase\u00f1or-Altamirano, A.B., Balderas-Mart\u00ednez, Y.I., Medina-Rivera, A.: Review of gene expression using microarray and rna-seq. In: Rigor and Reproducibility in Genetics and Genomics, pp. 159\u2013187. Elsevier (2024)","DOI":"10.1016\/B978-0-12-817218-6.00008-5"},{"key":"4_CR22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13059-017-1319-7","volume":"18","author":"A Zielezinski","year":"2017","unstructured":"Zielezinski, A., Vinga, S., Almeida, J., Karlowski, W.M.: Alignment-free sequence comparison: benefits, applications, and tools. Genome Biol. 18, 1\u201317 (2017)","journal-title":"Genome Biol."}],"container-title":["Communications in Computer and Information Science","Advanced Research in Technologies, Information, Innovation and Sustainability"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-032-16848-1_4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T13:08:00Z","timestamp":1772802480000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-032-16848-1_4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"ISBN":["9783032168474","9783032168481"],"references-count":22,"URL":"https:\/\/doi.org\/10.1007\/978-3-032-16848-1_4","relation":{},"ISSN":["1865-0929","1865-0937"],"issn-type":[{"value":"1865-0929","type":"print"},{"value":"1865-0937","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"1 April 2026","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}},{"value":"ARTIIS","order":1,"name":"conference_acronym","label":"Conference Acronym","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"International Conference on Advanced Research in Technologies, Information, Innovation and Sustainability","order":2,"name":"conference_name","label":"Conference Name","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Cartagena de Indias","order":3,"name":"conference_city","label":"Conference City","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"Colombia","order":4,"name":"conference_country","label":"Conference Country","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"2025","order":5,"name":"conference_year","label":"Conference Year","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"21 October 2025","order":7,"name":"conference_start_date","label":"Conference Start Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"23 October 2025","order":8,"name":"conference_end_date","label":"Conference End Date","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"5","order":9,"name":"conference_number","label":"Conference Number","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"artiis2025","order":10,"name":"conference_id","label":"Conference ID","group":{"name":"ConferenceInfo","label":"Conference Information"}},{"value":"https:\/\/artiis.org","order":11,"name":"conference_url","label":"Conference URL","group":{"name":"ConferenceInfo","label":"Conference Information"}}]}}