{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,26]],"date-time":"2025-03-26T01:55:24Z","timestamp":1742954124458,"version":"3.40.3"},"publisher-location":"Cham","reference-count":31,"publisher":"Springer International Publishing","isbn-type":[{"type":"print","value":"9783319081229"},{"type":"electronic","value":"9783319081236"}],"license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014]]},"DOI":"10.1007\/978-3-319-08123-6_6","type":"book-chapter","created":{"date-parts":[[2014,7,7]],"date-time":"2014-07-07T13:08:12Z","timestamp":1404738492000},"page":"67-79","source":"Crossref","is-referenced-by-count":0,"title":["Simulating Cancer Growth Using Cellular Automata to Detect Combination Drug Targets"],"prefix":"10.1007","author":[{"given":"Jenna","family":"Butler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frances","family":"Mackay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin","family":"Denniston","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Daley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"issue":"12","key":"6_CR1","first-page":"34","volume":"4","author":"R. Abbott","year":"2006","unstructured":"Abbott, R., Forrest, S., Pienta, K.: Simulating the hallmarks of cancer. Artificial Life\u00a04(12), 34\u2013617 (2006)","journal-title":"Artificial Life"},{"issue":"3","key":"6_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1051\/mmnp:2007001","volume":"2","author":"A.R.A. Anderson","year":"2008","unstructured":"Anderson, A.R.A., Rejniak, K.A., Gerlee, P., Quaranta, V.: Modelling of Cancer Growth, Evolution and Invasion: Bridging Scales and Models. Mathematical Modelling of Natural Phenomena\u00a02(3), 1\u201329 (2008), http:\/\/www.mmnp-journal.org\/10.1051\/mmnp:2007001","journal-title":"Mathematical Modelling of Natural Phenomena"},{"issue":"3","key":"6_CR3","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1038\/nrc2329","volume":"8","author":"A.R.A. Anderson","year":"2008","unstructured":"Anderson, A.R.A., Quaranta, V.: Integrative mathematical oncology. Nature Reviews Cancer\u00a08(3), 227\u2013234 (2008), http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18273038","journal-title":"Nature Reviews Cancer"},{"issue":"5","key":"6_CR4","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1016\/j.cell.2006.09.042","volume":"127","author":"A.R.A. Anderson","year":"2006","unstructured":"Anderson, A.R.A., Weaver, A.M., Cummings, P.T., Quaranta, V.: Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment. Cell\u00a0127(5), 905\u2013915 (2006), http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17129778","journal-title":"Cell"},{"issue":"1","key":"6_CR5","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.mbs.2010.10.005","volume":"229","author":"D. Basanta","year":"2011","unstructured":"Basanta, D., Ribba, B., Watkin, E., You, B., Deutsch, A.: Computational analysis of the influence of the microenvironment on carcinogenesis. Mathematical Biosciences\u00a0229(1), 22\u201329 (2011), http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0025556410001616","journal-title":"Mathematical Biosciences"},{"issue":"13","key":"6_CR6","doi-asserted-by":"publisher","first-page":"4527","DOI":"10.1158\/1078-0432.CCR-04-0194","volume":"10","author":"L. Bello","year":"2004","unstructured":"Bello, L., Lucini, V., Costa, F., Pluderi, M., Giussani, C., Acerbi, F., Carrabba, G., Pannacci, M., Caronzolo, D., Grosso, S., et al.: Combinatorial administration of molecules that simultaneously inhibit angiogenesis and invasion leads to increased therapeutic efficacy in mouse models of malignant glioma. Clinical Cancer Research\u00a010(13), 4527\u20134537 (2004)","journal-title":"Clinical Cancer Research"},{"key":"6_CR7","unstructured":"Bellomo, N., De Angelis, E.: Selected topics in cancer modeling: genesis, evolution, immune competition, and therapy. Springer (2008)"},{"key":"6_CR8","unstructured":"Bentley, K., Bates, P., Gerhardt, H.: Artificial life as cancer research: Embodied agent modelling of blood vessel growth in tumours. In: Proceedings of Artifical Life XI (2008)"},{"issue":"3","key":"6_CR9","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1016\/j.ccr.2009.01.021","volume":"15","author":"J.M.L. Ebos","year":"2009","unstructured":"Ebos, J.M.L., Lee, C.R., Cruz-Munoz, W., Bjarnason, G.A., Christensen, J.G., Kerbel, R.S.: Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis. Cancer Cell\u00a015(3), 232\u2013239 (2009), http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19249681","journal-title":"Cancer Cell"},{"issue":"4","key":"6_CR10","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1016\/j.jtbi.2007.01.027","volume":"246","author":"P. Gerlee","year":"2007","unstructured":"Gerlee, P., Anderson, A.R.A.: An evolutionary hybrid cellular automaton model of solid tumour growth. Journal of Theoretical Biology\u00a0246(4), 583\u2013603 (2007)","journal-title":"Journal of Theoretical Biology"},{"key":"6_CR11","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/j.jtbi.2007.10.038","volume":"250","author":"P. Gerlee","year":"2008","unstructured":"Gerlee, P., Anderson, A.R.A.: A hybrid cellular automaton model of clonal evolution in cancer: The emergence of the glycolytic phenotype. Journal of Theoretical Biology\u00a0250, 705\u2013722 (2008)","journal-title":"Journal of Theoretical Biology"},{"issue":"1","key":"6_CR12","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.jtbi.2009.03.005","volume":"259","author":"P. Gerlee","year":"2009","unstructured":"Gerlee, P., Anderson, A.R.A.: Evolution of cell motility in an individual-based model of tumour growth. Journal of Theoretical Biology\u00a0259(1), 67\u201383 (2009)","journal-title":"Journal of Theoretical Biology"},{"key":"6_CR13","doi-asserted-by":"crossref","unstructured":"Gevertz, J.L., Gillies, G.T., Torquato, S.: Simulating tumor growth in confined heterogeneous environments. Physical Biology\u00a05(3) (2008), http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18824788","DOI":"10.1088\/1478-3975\/5\/3\/036010"},{"issue":"1","key":"6_CR14","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/S0092-8674(00)81683-9","volume":"100","author":"D. Hanahan","year":"2000","unstructured":"Hanahan, D., Weinberg, R.: The hallmarks of cancer. Cell\u00a0100(1), 57\u201370 (2000)","journal-title":"Cell"},{"issue":"5","key":"6_CR15","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1016\/j.cell.2011.02.013","volume":"144","author":"D. Hanahan","year":"2011","unstructured":"Hanahan, D., Weinberg, R.: Hallmarks of cancer: the next generation. Cell\u00a0144(5), 646\u2013674 (2011)","journal-title":"Cell"},{"issue":"12","key":"6_CR16","first-page":"2272","volume":"29","author":"E. Henderson","year":"1969","unstructured":"Henderson, E., Samaha, R.: Evidence that drugs in multiple combinations have materially advanced the treatment of human malignancies. Cancer Research\u00a029(12), 2272\u20132280 (1969)","journal-title":"Cancer Research"},{"issue":"2","key":"6_CR17","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/j.jtbi.2010.02.027","volume":"264","author":"Y. Hirata","year":"2010","unstructured":"Hirata, Y., Bruchovsky, N., Aihara, K.: Development of a mathematical model that predicts the outcome of hormone therapy for prostate cancer. Journal of Theoretical Biology\u00a0264(2), 517\u2013527 (2010), http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20176032","journal-title":"Journal of Theoretical Biology"},{"issue":"2","key":"6_CR18","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1002\/jcp.22766","volume":"227","author":"Y. Kam","year":"2012","unstructured":"Kam, Y., Rejniak, K.A., Anderson, A.R.A.: Cellular modeling of cancer invasion: integration of in silico and in vitro approaches. Journal of Cellular Physiology\u00a0227(2), 431\u2013438 (2012), http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21465465","journal-title":"Journal of Cellular Physiology"},{"issue":"1879","key":"6_CR19","doi-asserted-by":"publisher","first-page":"3301","DOI":"10.1098\/rsta.2008.0092","volume":"366","author":"B.A. Lloyd","year":"2008","unstructured":"Lloyd, B.A., Szczerba, D., Rudin, M., Sz\u00e9kely, G.: A computational framework for modelling solid tumour growth. Philosophical transactions, Series A, Mathematical, physical, and engineering sciences\u00a0366(1879), 3301\u20133318 (2008), http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18593664","journal-title":"Philosophical transactions, Series A, Mathematical, physical, and engineering sciences"},{"key":"6_CR20","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.jtbi.2012.02.002","volume":"301","author":"P. Macklin","year":"2011","unstructured":"Macklin, P., Edgerton, M.E., Thompson, A., Cristini, V.: Patient-calibrated agent-based modelling of ductal carcinoma in situ (DCIS) I: Model formulation and analysis. Journal of Theoretical Biology\u00a0301, 122\u2013140 (2011)","journal-title":"Journal of Theoretical Biology"},{"key":"6_CR21","doi-asserted-by":"crossref","unstructured":"Maley, C.C., Forrest, S.: Modelling the role of neutral and selective mutations in cancer. In: Artificial Life VII: Proceedings of the Seventh International Conference on Artificial Life, pp. 395\u2013404 (2000)","DOI":"10.7551\/mitpress\/1432.003.0056"},{"issue":"5-6","key":"6_CR22","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1016\/j.mcm.2007.02.034","volume":"47","author":"I. Ramis-Conde","year":"2008","unstructured":"Ramis-Conde, I., Chaplain, M.A.J., Anderson, A.R.: Mathematical modelling of cancer cell invasion of tissue. Mathematical and Computer Modelling\u00a047(5-6), 533\u2013545 (2008), http:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0895717707001823","journal-title":"Mathematical and Computer Modelling"},{"issue":"1","key":"6_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/imammb\/dqr029","volume":"29","author":"K.A. Rejniak","year":"2012","unstructured":"Rejniak, K.A., Anderson, A.R.A.: State of the art in computational modelling of cancer. Mathematical Medicine and Biology\u00a029(1), 1\u20132 (2012), http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22200587","journal-title":"Mathematical Medicine and Biology"},{"issue":"1","key":"6_CR24","first-page":"115","volume":"3","author":"K.A. Rejniak","year":"2011","unstructured":"Rejniak, K.A., Anderson, A.R.: Hybrid models of tumor growth. Wiley Interdisciplinary Reviews: Systems Biology and Medicine\u00a03(1), 115\u2013125 (2011)","journal-title":"Wiley Interdisciplinary Reviews: Systems Biology and Medicine"},{"key":"6_CR25","series-title":"Lecture Notes in Computer Science","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1007\/978-3-540-30479-1_46","volume-title":"Cellular Automata","author":"B. Ribba","year":"2004","unstructured":"Ribba, B., Alarc\u00f3n, T., Marron, K., Maini, P.K., Agur, Z.: The use of hybrid cellular automaton models for improving cancer therapy. In: Sloot, P.M.A., Chopard, B., Hoekstra, A.G. (eds.) ACRI 2004. LNCS, vol.\u00a03305, pp. 444\u2013453. Springer, Heidelberg (2004)"},{"key":"6_CR26","series-title":"Lecture Notes in Computer Science","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1007\/978-3-642-32937-1_49","volume-title":"Parallel Problem Solving from Nature - PPSN XII","author":"J. Santos","year":"2012","unstructured":"Santos, J., Monteagudo, \u00c1.: Study of cancer hallmarks relevance using a cellular automaton tumor growth model. In: Coello, C.A.C., Cutello, V., Deb, K., Forrest, S., Nicosia, G., Pavone, M. (eds.) PPSN 2012, Part I. LNCS, vol.\u00a07491, pp. 489\u2013499. Springer, Heidelberg (2012)"},{"issue":"1","key":"6_CR27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S1072-7515(99)00075-7","volume":"189","author":"S. Sener","year":"1999","unstructured":"Sener, S., Fremgen, A., Menck, H., Winchester, D.: Pancreatic cancer: A report of treatment and survival trends for 100,313 patients diagnosed from 1985\u20131995, using the national cancer database. Journal of the American College of Surgeons\u00a0189(1), 1\u20137 (1999)","journal-title":"Journal of the American College of Surgeons"},{"key":"6_CR28","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1002\/cnm.2539","volume":"29","author":"S. Shrestha","year":"2013","unstructured":"Shrestha, S., Joldes, G.R., Wittek, A., Miller, K.: Cellular automata coupled with steady-state nutrient solution permit simulation of large-scale growth of tumours. International Journal for Numerical Methods in Biomedical Engineering\u00a029, 542\u2013559 (2013)","journal-title":"International Journal for Numerical Methods in Biomedical Engineering"},{"key":"6_CR29","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/j.jtbi.2004.07.006","volume":"231","author":"S. Spencer","year":"2004","unstructured":"Spencer, S., Berryman, M., Garcia, J., Abbott, D.: An ordinary differential equation model for the multistep transformation to cancer. Journal of Theoretical Biology\u00a0231, 515\u2013524 (2004)","journal-title":"Journal of Theoretical Biology"},{"key":"6_CR30","unstructured":"StatCan: Leading causes of death, by sex. Statistics Canada (2009)"},{"issue":"1","key":"6_CR31","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1186\/1471-2105-13-218","volume":"13","author":"X. Sun","year":"2012","unstructured":"Sun, X., Zhang, L., Tan, H., Bao, J., Strouthos, C., Zhou, X.: Multi-scale agent-based brain cancer modeling and prediction of TKI treatment response: Incorporating EGFR signaling pathway and angiogenesis. BMC Bioinformatics\u00a013(1), 218 (2012), http:\/\/www.biomedcentral.com\/1471-2105\/13\/218","journal-title":"BMC Bioinformatics"}],"container-title":["Lecture Notes in Computer Science","Unconventional Computation and Natural Computation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-319-08123-6_6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T05:51:55Z","timestamp":1716961915000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-319-08123-6_6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"ISBN":["9783319081229","9783319081236"],"references-count":31,"URL":"https:\/\/doi.org\/10.1007\/978-3-319-08123-6_6","relation":{},"ISSN":["0302-9743","1611-3349"],"issn-type":[{"type":"print","value":"0302-9743"},{"type":"electronic","value":"1611-3349"}],"subject":[],"published":{"date-parts":[[2014]]}}}