{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T09:12:36Z","timestamp":1762161156808,"version":"3.40.3"},"publisher-location":"Cham","reference-count":28,"publisher":"Springer International Publishing","isbn-type":[{"type":"print","value":"9783319171203"},{"type":"electronic","value":"9783319171210"}],"license":[{"start":{"date-parts":[[2015,10,2]],"date-time":"2015-10-02T00:00:00Z","timestamp":1443744000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016]]},"DOI":"10.1007\/978-3-319-17121-0_61","type":"book-chapter","created":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T12:47:47Z","timestamp":1443703667000},"page":"455-461","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Histone Deacetylase: Therapeutic Targets in Retinal Degeneration"],"prefix":"10.1007","author":[{"given":"Conor","family":"Daly","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Breand\u00e1n N.","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,10,2]]},"reference":[{"key":"61_CR1","doi-asserted-by":"publisher","first-page":"1328","DOI":"10.1101\/gr.116012.110","volume":"21","author":"H Aanes","year":"2011","unstructured":"Aanes H, Winata CL, Lin CH et\u00a0al (2011) Zebrafish mRNA sequencing deciphers novelties in transcriptome dynamics during maternal to zygotic transition. Genome Res 21:1328\u20131338","journal-title":"Genome Res"},{"key":"61_CR2","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.brainres.2006.10.031","volume":"1129","author":"S Azadi","year":"2007","unstructured":"Azadi S, Johnson LE, Paquet-Durand F et\u00a0al (2007) CNTF+ BDNF treatment and neuroprotective pathways in the rd1 mouse retina. Brain Res 1129:116\u2013129","journal-title":"Brain Res"},{"key":"61_CR3","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1136\/bjophthalmol-2013-303084","volume":"97","author":"S Bhalla","year":"2013","unstructured":"Bhalla S, Joshi D, Bhullar S et\u00a0al (2013) Long-term follow-up for efficacy and safety of treatment of retinitis pigmentosa with valproic acid. Br J Ophthalmol 97:895\u2013899","journal-title":"Br J Ophthalmol"},{"key":"61_CR4","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1126\/science.1175371","volume":"325","author":"C Choudhary","year":"2009","unstructured":"Choudhary C, Kuman C, Gnad F et\u00a0al (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325:834\u2013840","journal-title":"Science"},{"key":"61_CR5","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1136\/bjo.2009.175356","volume":"95","author":"CM Clemson","year":"2011","unstructured":"Clemson CM, Tzekov R, Krebs M et\u00a0al (2011) Therapeutic potential of valproic acid for retinitis pigmentosa. Br J Ophthalmol 95:89\u201393","journal-title":"Br J Ophthalmol"},{"key":"61_CR6","doi-asserted-by":"publisher","first-page":"2067","DOI":"10.1101\/gr.137901.112","volume":"22","author":"JE Collins","year":"2012","unstructured":"Collins JE, White S, Searle SM et\u00a0al (2012) Incorporating RNA-seq data into the zebrafish Ensembl genebuild. Genome Res 22:2067\u20132078","journal-title":"Genome Res"},{"key":"61_CR7","doi-asserted-by":"publisher","first-page":"3639","DOI":"10.1167\/iovs.09-4538","volume":"51","author":"CE Crosson","year":"2010","unstructured":"Crosson CE, Mani SK, Husain S et\u00a0al (2010) Inhibition of histone deacetylase protects the retina from ischemic injury. Invest Ophthalmol Vis Sci 51:3639\u20133645","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"61_CR8","doi-asserted-by":"publisher","first-page":"2983","DOI":"10.1242\/dev.01166","volume":"131","author":"VT Cunliffe","year":"2004","unstructured":"Cunliffe VT (2004) Histone deacetylase 1 is required to repress Notch target gene expression during zebrafish neurogenesis and to maintain the production of motoneurones in response to hedgehog signalling. Development 131:2983\u20132995","journal-title":"Development"},{"issue":"11","key":"61_CR9","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1002\/dvdy.24173","volume":"243","author":"Miki Dozawa","year":"2014","unstructured":"Dozawa M, Kono H, Sato Y et\u00a0al (2014) Valproic acid, a histone deacetylase inhibitor, regulates cell proliferation in the adult zebrafish optic tectum. Dev Dyn 243(11):1401\u20131415","journal-title":"Developmental Dynamics"},{"key":"61_CR10","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1006\/dbio.1996.0335","volume":"180","author":"SS Easter","year":"1996","unstructured":"Easter SS, Nicola GN (1996) The development of vision in the zebrafish (Danio rerio). Dev Biol 180:646\u2013663","journal-title":"Dev Biol"},{"key":"61_CR11","doi-asserted-by":"publisher","first-page":"e85408","DOI":"10.1371\/journal.pone.0085408","volume":"8","author":"S Genini","year":"2013","unstructured":"Genini S, Beltran WA, Aguirre GD (2013) Up-regulation of tumor necrosis factor superfamily genes in early phases of photoreceptor degeneration. PLoS One 8:e85408","journal-title":"PLoS One"},{"key":"61_CR12","doi-asserted-by":"publisher","first-page":"2929","DOI":"10.1167\/iovs.03-1184","volume":"45","author":"A Hackam","year":"2004","unstructured":"Hackam A, Strom R, Liu D et\u00a0al (2004) Identification of gene expression changes associated with the progression of retinal degeneration in the rd1 mouse. Invest Opthalmol Vis Sci 45:2929\u20132942","journal-title":"Invest Opthalmol Vis Sci"},{"key":"61_CR13","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1111\/cpr.12081","volume":"47","author":"Y He","year":"2014","unstructured":"He Y, Wu J, Mei H et\u00a0al (2014) Histone deacetylase activity is required for embryonic posterior lateral line development. Cell Prolif 47:91\u2013104","journal-title":"Cell Prolif"},{"key":"61_CR14","doi-asserted-by":"publisher","first-page":"7436","DOI":"10.1074\/jbc.M808999200","volume":"284","author":"VD Kekatpure","year":"2009","unstructured":"Kekatpure VD, Dannenberg AJ, Subbaramaiah K (2009) HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling. J Biol Chem 284:7436\u20137445","journal-title":"J Biol Chem"},{"key":"61_CR15","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/aja.1002030302","volume":"203","author":"CB Kimmel","year":"1995","unstructured":"Kimmel CB, Ballard WW, Kimmel SR et\u00a0al (1995) Stages of embryonic development of the zebrafish. Dev Dyn 203:253\u2013310","journal-title":"Dev Dyn"},{"key":"61_CR16","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/j.neuropharm.2013.07.015","volume":"75","author":"I Koppel","year":"2013","unstructured":"Koppel I, Timmusk T (2013) Differential regulation of Bdnf expression in cortical neurons by class-selective histone deacetylase inhibitors. Neuropharm 75:106\u2013115","journal-title":"Neuropharm"},{"key":"61_CR18","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1002\/dvdy.20168","volume":"231","author":"R Pillai","year":"2004","unstructured":"Pillai R, Coverdale LE, Dubey G et\u00a0al (2004) Histone deacetylase 1 (HDAC-1) required for the normal formation of craniofacial cartilage and pectoral fins of the zebrafish. Dev Dyn 231:647\u2013654","journal-title":"Dev Dyn"},{"key":"61_CR19","doi-asserted-by":"publisher","first-page":"e488","DOI":"10.1038\/cddis.2013.12","volume":"4","author":"A Sahaboglu","year":"2013","unstructured":"Sahaboglu A, Paquet-Durand O, Dietter J et\u00a0al (2013) Retinitis pigmentosa: rapid neurodegeneration is governed by slow cell death mechanisms. Cell Death Dis 4:e488","journal-title":"Cell Death Dis"},{"key":"61_CR20","doi-asserted-by":"publisher","first-page":"e24","DOI":"10.1038\/cddis.2010.4","volume":"1","author":"J Sancho-Pelluz","year":"2010","unstructured":"Sancho-Pelluz J, Alavi MV, Sahaboglu A et\u00a0al (2010) Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse. Cell Death Dis 1:e24","journal-title":"Cell Death Dis"},{"key":"61_CR21","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1136\/bjo.2010.198176","volume":"95","author":"MA Sandberg","year":"2011","unstructured":"Sandberg MA, Rosner B, Weigel-DiFranco C et\u00a0al (2011) Lack of scientific rationale for use of valproic acid for retinitis pigmentosa. Br J Ophthalmol 95:744","journal-title":"Br J Ophthalmol"},{"key":"61_CR22","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.molcel.2006.12.008","volume":"25","author":"BT Scroggins","year":"2007","unstructured":"Scroggins BT, Robzyk K, Wang D et\u00a0al (2007) An acetylation site in the middle domain of Hsp90 regulates chaperone function. Mol Cell 25:151\u2013159","journal-title":"Mol Cell"},{"key":"61_CR23","doi-asserted-by":"publisher","first-page":"1154","DOI":"10.1136\/bjophthalmol-2012-301950","volume":"96","author":"RA Sisk","year":"2012","unstructured":"Sisk RA (2012) Valproic acid treatment may be harmful in non-dominant forms of retinitis pigmentosa. Br J Ophthalmol 96:1154\u20131155","journal-title":"Br J Ophthalmol"},{"key":"61_CR24","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1002\/dvdy.20427","volume":"233","author":"JA Stadler","year":"2005","unstructured":"Stadler JA, Shkumatava A, Norton WH et\u00a0al (2005) Histone deacetylase 1 is required for cell cycle exit and differentiation in the zebrafish retina. Dev Dyn 233:883\u2013889","journal-title":"Dev Dyn"},{"doi-asserted-by":"crossref","unstructured":"van Schooneveld, MJ et al (2011) The conclusions of Clemson et al concerning valproic acid are premature. Br J Ophthalmol 95(1):153-154","key":"61_CR100","DOI":"10.1136\/bjo.2010.194373"},{"key":"61_CR25","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1016\/j.neuroscience.2008.08.006","volume":"156","author":"XR Wen","year":"2008","unstructured":"Wen XR, Li C, Zong Y et\u00a0al (2008) Dual inhibitory roles of geldanamycin on the c-Jun NH2-terminal kinase 3 signal pathway through suppressing the expression of mixed-lineage kinase 3 and attenuating the activation of apoptosis signal-regulating kinase 1 via facilitating the activation of Akt in ischemic brain injury. Neuroscience 156:483\u2013497","journal-title":"Neuroscience"},{"key":"61_CR26","doi-asserted-by":"publisher","first-page":"3027","DOI":"10.1242\/dev.01881","volume":"132","author":"M Yamaguchi","year":"2005","unstructured":"Yamaguchi M, Tonou-Fujimori N, Komori A et\u00a0al (2005). Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways. Development 132:3027\u20133043","journal-title":"Development"},{"key":"61_CR27","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1038\/nrm2346","volume":"9","author":"XJ Yang","year":"2008","unstructured":"Yang XJ, Seto E (2008) The Rpd3\/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men. Nat Rev Mol Cell Biol 9:206\u2013218","journal-title":"Nat Rev Mol Cell Biol"},{"key":"61_CR28","doi-asserted-by":"publisher","first-page":"e52177","DOI":"10.1371\/journal.pone.0052177","volume":"7","author":"J Yin","year":"2012","unstructured":"Yin J, Shine L, Raycroft F et\u00a0al (2012) Inhibition of the pim1 oncogene results in diminished visual function. PLoS One 7:e52177","journal-title":"PLoS One"}],"container-title":["Advances in Experimental Medicine and Biology","Retinal Degenerative Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-319-17121-0_61","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,15]],"date-time":"2023-02-15T16:22:48Z","timestamp":1676478168000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-319-17121-0_61"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,2]]},"ISBN":["9783319171203","9783319171210"],"references-count":28,"URL":"https:\/\/doi.org\/10.1007\/978-3-319-17121-0_61","relation":{},"ISSN":["0065-2598","2214-8019"],"issn-type":[{"type":"print","value":"0065-2598"},{"type":"electronic","value":"2214-8019"}],"subject":[],"published":{"date-parts":[[2015,10,2]]},"assertion":[{"value":"2 October 2015","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}