{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T01:03:04Z","timestamp":1725843784348},"publisher-location":"Cham","reference-count":12,"publisher":"Springer International Publishing","isbn-type":[{"type":"print","value":"9783319273396"},{"type":"electronic","value":"9783319273402"}],"license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015]]},"DOI":"10.1007\/978-3-319-27340-2_38","type":"book-chapter","created":{"date-parts":[[2015,12,16]],"date-time":"2015-12-16T13:40:44Z","timestamp":1450273244000},"page":"302-309","source":"Crossref","is-referenced-by-count":1,"title":["Classification of the States of Human Adaptive Immune Systems by Analyzing Immunoglobulin and T Cell Receptors Using ImmunExplorer"],"prefix":"10.1007","author":[{"given":"Susanne","family":"Schaller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Weinberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ra\u00fal","family":"Jim\u00e9nez-Heredia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Danzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan M.","family":"Winkler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,12,17]]},"reference":[{"key":"38_CR1","doi-asserted-by":"crossref","unstructured":"Reis-Filho, J.S., others: Next-generation sequencing. 11 (2009) S12","DOI":"10.1186\/bcr2431"},{"key":"38_CR2","first-page":"26","volume":"8","author":"E Alamyar","year":"2012","unstructured":"Alamyar, E., Giudicelli, V., Li, S., Duroux, P., Lefranc, M.P.: IMGT\/HighV-QUEST: the IMGT web portal for immunoglobulin (IG) or antibody and t cell receptor (TR) analysis from NGS high throughput and deep sequencing. Immunome research 8, 26 (2012)","journal-title":"Immunome research"},{"key":"38_CR3","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1038\/ncomms3333","volume":"4","author":"S Li","year":"2013","unstructured":"Li, S., Lefranc, M.P., Miles, J.J., Alamyar, E., Giudicelli, V., Duroux, P., Freeman, J.D., Corbin, V.D.A., Scheerlinck, J.P., Frohman, M.A., Cameron, P.U., Plebanski, M., Loveland, B., Burrows, S.R., Papenfuss, A.T., Gowans, E.J.: IMGT\/HighV QUEST paradigm for t cell receptor IMGT clonotype diversity and next generation repertoire immunoprofiling. Nature Communications 4, 2333 (2013)","journal-title":"Nature Communications"},{"key":"38_CR4","series-title":"Methods in Molecular Biology (Clifton, N.J.)","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1007\/978-1-61779-842-9_32","volume-title":"Immunogenetics","author":"E Alamyar","year":"2012","unstructured":"Alamyar, E., Duroux, P., Lefranc, M.P., Giudicelli, V.: IMGT() tools for the nucleotide analysis of immunoglobulin (IG) and t cell receptor (TR) v-(d)-j repertoires, polymorphisms, and IG mutations: IMGT\/v-QUEST and IMGT\/HighV-QUEST for NGS. In: Christiansen, F.T., Tait, B.D. (eds.) Immunogenetics. Methods in Molecular Biology (Clifton, N.J.), vol. 882, pp. 569\u2013604. Springer, Heidelberg (2012)"},{"key":"38_CR5","doi-asserted-by":"crossref","unstructured":"Giudicelli, V., Chaume, D., Lefranc, M.P.: IMGT\/GENE-DB: a comprehensive database for human and mouse immunoglobulin and t cell receptor genes. Nucleic Acids Research (33) D256\u2013D261","DOI":"10.1093\/nar\/gki010"},{"key":"38_CR6","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1136\/mp.55.2.98","volume":"55","author":"TC Diss","year":"2002","unstructured":"Diss, T.C., Liu, H.X., Du, M.Q., Isaacson, P.G.: Improvements to b cell clonality analysis using PCR amplification of immunoglobulin light chain genes. Molecular Pathology 55, 98\u2013101 (2002)","journal-title":"Molecular Pathology"},{"key":"38_CR7","unstructured":"Schaller, S., Weinberger, J., Danzer, M., Gabriel, C., Oberbauer, R., Winkler, S.M.: Mathematical modeling of the diversity in human b- and t-cell receptors using machine learning. In: Proceedings of the 26th European Modeling and Simulation Symposium. (2014)"},{"key":"38_CR8","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1007\/BF01876146","volume":"1","author":"HP Schwefel","year":"1984","unstructured":"Schwefel, H.P.: Evolution strategies: A family of non-linear optimization techniques based on imitating some principles of organic evolution. Annals of Operations Research 1, 165\u2013167 (1984)","journal-title":"Annals of Operations Research"},{"key":"38_CR9","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1023\/A:1010933404324","volume":"45","author":"L Breiman","year":"2001","unstructured":"Breiman, L.: Random forests. Machine Learning 45, 5\u201332 (2001)","journal-title":"Machine Learning"},{"key":"38_CR10","unstructured":"Haykin, S.: Neural Networks. A Comprehensive Foundation. Prentice-Hall, Upper Saddle River NJ (1999)"},{"key":"38_CR11","unstructured":"Koza, J.R.: Genetic Programming: On the Programming of Computers by Means of Natural Selection. The MIT Press (1992)"},{"key":"38_CR12","series-title":"Topics in Intelligent Engineering and Informatics","first-page":"193","volume-title":"Advanced Methods and Applications in Computational Intelligence","author":"S Wagner","year":"2013","unstructured":"Wagner, S., Kronberger, G., Beham, A., Kommenda, M., Scheibenpflug, A., Pitzer, E., Vonolfen, S., Kofler, M., Winkler, S., Dorfer, V., Affenzeller, M.: Architecture and Design of the HeuristicLab Optimization Environment. In: Klempous, R., Nikodem, J., Jacak, W., Chaczko, Z. (eds.) Advanced Methods and Applications in Computational Intelligence. TIEI, vol. 6, pp. 193\u2013258. Springer, Heidelberg (2013)"}],"container-title":["Lecture Notes in Computer Science","Computer Aided Systems Theory \u2013 EUROCAST 2015"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-319-27340-2_38","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,31]],"date-time":"2019-05-31T20:23:27Z","timestamp":1559334207000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-319-27340-2_38"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"ISBN":["9783319273396","9783319273402"],"references-count":12,"URL":"https:\/\/doi.org\/10.1007\/978-3-319-27340-2_38","relation":{},"ISSN":["0302-9743","1611-3349"],"issn-type":[{"type":"print","value":"0302-9743"},{"type":"electronic","value":"1611-3349"}],"subject":[],"published":{"date-parts":[[2015]]}}}