{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T04:56:58Z","timestamp":1789880218245,"version":"4.0.1"},"publisher-location":"Cham","reference-count":17,"publisher":"Springer International Publishing","isbn-type":[{"value":"9783319283814","type":"print"},{"value":"9783319283838","type":"electronic"}],"license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016]]},"DOI":"10.1007\/978-3-319-28383-8_9","type":"book-chapter","created":{"date-parts":[[2016,9,20]],"date-time":"2016-09-20T09:03:55Z","timestamp":1474362235000},"page":"153-171","source":"Crossref","is-referenced-by-count":10,"title":["Role of Plant Polyphenols in Alzheimer\u2019s Disease"],"prefix":"10.1007","author":[{"given":"Arokiasamy Justin","family":"Thenmozhi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thamilarasan","family":"Manivasagam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Musthafa Mohamed","family":"Essa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,9,21]]},"reference":[{"key":"9_CR1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.5114\/fn.2013.37702","volume":"51","author":"RA Armstrong","year":"2013","unstructured":"Armstrong RA. What causes Alzheimer\u2019s disease? Folia Neuropathol. 2013;51:169\u201388.","journal-title":"Folia Neuropathol"},{"key":"9_CR2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12017-009-8104-z","volume":"12","author":"VW Chow","year":"2010","unstructured":"Chow VW, Mattson MP, Wong PC, Gleichmann M. An overview of APP processing enzymes and products. Neuromolecular Med. 2010;12:1\u201312.","journal-title":"Neuromolecular Med"},{"key":"9_CR3","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.abb.2010.05.003","volume":"501","author":"S Chung","year":"2010","unstructured":"Chung S, Yao H, Caito S, Hwang JW, Arunachalam G, Rahman I. Regulation of SIRT1 in cellular functions: role of polyphenols. Arch Biochem Biophys. 2010;501:79\u201390.","journal-title":"Arch Biochem Biophys"},{"key":"9_CR4","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.arr.2012.01.006","volume":"11","author":"A Ebrahimi","year":"2012","unstructured":"Ebrahimi A, Schluesener H. Natural polyphenols against neurodegenerative disorders: potentials and pitfalls. Ageing Res Rev. 2012;11:329\u201345.","journal-title":"Ageing Res Rev"},{"key":"9_CR5","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/s00439-011-1119-1","volume":"131","author":"MA Gama Sosa","year":"2012","unstructured":"Gama Sosa MA, De Gasperi R, Elder GA. Modeling human neurodegenerative diseases in transgenic systems. Hum Genet. 2012;131:535\u201363.","journal-title":"Hum Genet"},{"key":"9_CR6","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1007\/s11064-015-1525-1","volume":"40","author":"A Justin Thenmozhi","year":"2015","unstructured":"Justin Thenmozhi A, Raja TR, Janakiraman U, Manivasagam T. Neuroprotective effect of hesperidin on aluminium chloride induced Alzheimer\u2019s disease in Wistar rats. Neurochem Res. 2015;40:767\u201376.","journal-title":"Neurochem Res"},{"key":"9_CR7","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.pharep.2014.09.004","volume":"67","author":"A Kumar","year":"2015","unstructured":"Kumar A, Singh A, Ekavali. A review on Alzheimer\u2019s disease pathophysiology and its management: an update. Pharmacol Rep. 2015;67:195\u2013203.","journal-title":"Pharmacol Rep"},{"key":"9_CR8","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/j.arr.2011.03.002","volume":"10","author":"AV Maltsev","year":"2011","unstructured":"Maltsev AV, Bystryak S, Galzitskaya OV. The role of \u03b2-amyloid peptide in neurodegenerative diseases. Ageing Res Rev. 2011;10:440\u201352.","journal-title":"Ageing Res Rev"},{"key":"9_CR9","doi-asserted-by":"crossref","first-page":"69","DOI":"10.2174\/157015910790909520","volume":"8","author":"F Massoud","year":"2010","unstructured":"Massoud F, Gauthier S. Update on the pharmacological treatment of Alzheimer\u2019s disease. Curr Neuropharmacol. 2010;8:69\u201380.","journal-title":"Curr Neuropharmacol"},{"key":"9_CR10","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s00401-014-1371-2","volume":"129","author":"RM Nisbet","year":"2015","unstructured":"Nisbet RM, Polanco JC, Ittner LM, Gotz J. Tau aggregation and its interplay with amyloid-\u03b2. Acta Neuropathol. 2015;129:207\u201320.","journal-title":"Acta Neuropathol"},{"key":"9_CR11","first-page":"216","volume":"6","author":"ZM Qian","year":"2014","unstructured":"Qian ZM, Ke Y. Huperzine A: is it an effective disease-modifying drug for Alzheimer\u2019s disease? Front Aging Neurosci. 2014;6:216.","journal-title":"Front Aging Neurosci"},{"key":"9_CR12","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.ejphar.2006.06.025","volume":"545","author":"C Ramassamy","year":"2006","unstructured":"Ramassamy C. Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: a review of their intracellular targets. Eur J Pharmacol. 2006;545:51\u201364.","journal-title":"Eur J Pharmacol"},{"key":"9_CR012","doi-asserted-by":"crossref","unstructured":"Roskams AJ, Connor JR. Aluminum access to the brain: a role for transferrin and its receptors. Proc Natl Acad Sci USA 1990;87:9024\u20139027.","DOI":"10.1073\/pnas.87.22.9024"},{"key":"9_CR13","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1146\/annurev.nutr.22.111401.144957","volume":"22","author":"JA Ross","year":"2002","unstructured":"Ross JA, Kasum CM. Dietary flavonoids: bioavailability, metabolic effects, and safety. Annu Rev Nutr. 2002;22:19\u201334.","journal-title":"Annu Rev Nutr"},{"key":"9_CR14","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.ccr.2014.03.026","volume":"284","author":"M Rowinska-Zyrek","year":"2015","unstructured":"Rowinska-Zyrek M, Salerno M, Kozlowski H. Neurodegenerative diseases - understanding their molecular bases and progress in the development of potential treatments. Coord Chem Rev. 2015;284:298\u2013312.","journal-title":"Coord Chem Rev"},{"key":"9_CR120","doi-asserted-by":"crossref","unstructured":"Shimmyo Y, Kihara T, Akaike A, Niidome T, Sugimoto H. Epigallocatechin-3- gallate and curcumin suppress amyloid beta-induced beta-site APP cleaving enzyme-1 upregulation. Neuroreport 2008; 19:1329\u20131333.","DOI":"10.1097\/WNR.0b013e32830b8ae1"},{"key":"9_CR15","unstructured":"WHO dementia report (2006). World Health Organization."}],"updated-by":[{"DOI":"10.1007\/978-3-319-28383-8_24","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T00:00:00Z","timestamp":1479254400000}}],"container-title":["Advances in Neurobiology","The Benefits of Natural Products for Neurodegenerative Diseases"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-319-28383-8_9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T19:14:39Z","timestamp":1498331679000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-319-28383-8_9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"ISBN":["9783319283814","9783319283838"],"references-count":17,"URL":"https:\/\/doi.org\/10.1007\/978-3-319-28383-8_9","relation":{"erratum":[{"id-type":"doi","id":"10.1007\/978-3-319-28383-8_24","asserted-by":"object"}]},"ISSN":["2190-5215","2190-5223"],"issn-type":[{"value":"2190-5215","type":"print"},{"value":"2190-5223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}