{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T22:54:22Z","timestamp":1791327262409,"version":"4.3.1"},"publisher-location":"Cham","reference-count":112,"publisher":"Springer International Publishing","isbn-type":[{"value":"9783319411705","type":"print"},{"value":"9783319411712","type":"electronic"}],"license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016]]},"DOI":"10.1007\/978-3-319-41171-2_7","type":"book-chapter","created":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T11:11:21Z","timestamp":1469531481000},"page":"133-160","source":"Crossref","is-referenced-by-count":16,"title":["Listeria monocytogenes and the Inflammasome: From Cytosolic Bacteriolysis to Tumor Immunotherapy"],"prefix":"10.1007","author":[{"given":"Erin","family":"Theisen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John-Demian","family":"Sauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,7,27]]},"reference":[{"key":"7_CR1","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.immuni.2012.05.001","volume":"37","author":"A Akhter","year":"2012","unstructured":"Akhter A, Caution K, Abu Khweek A et al (2012) Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization. Immunity 37:35\u201347. doi: 10.1016\/j.immuni.2012.05.001","journal-title":"Immunity"},{"key":"7_CR2","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1038\/nature11250","volume":"488","author":"PK Anand","year":"2012","unstructured":"Anand PK, Malireddi RKS, Lukens JR et al (2012) NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens. Nature 488:389\u2013393. doi: 10.1038\/nature11250","journal-title":"Nature"},{"key":"7_CR3","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1084\/jem.20040976","volume":"200","author":"V Auerbuch","year":"2004","unstructured":"Auerbuch V, Brockstedt DG, Meyer-Morse N et al (2004) Mice lacking the type I interferon receptor are resistant to Listeria monocytogenes. J Exp Med 200:527\u2013533. doi: 10.1084\/jem.20040976","journal-title":"J Exp Med"},{"key":"7_CR4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000568","author":"KS Bahjat","year":"2009","unstructured":"Bahjat KS, Meyer-Morse N, Lemmens EE et al (2009) Suppression of cell-mediated immunity following recognition of phagosome-confined bacteria. PLoS Pathog. doi: 10.1371\/journal.ppat.1000568","journal-title":"PLoS Pathog"},{"key":"7_CR5","doi-asserted-by":"publisher","first-page":"3235","DOI":"10.1093\/emboj\/19.13.3235","volume":"19","author":"CR Beuz\u00f3n","year":"2000","unstructured":"Beuz\u00f3n CR, M\u00e9resse S, Unsworth KE et al (2000) Salmonella maintains the integrity of its intracellular vacuole through the action of SifA. EMBO J 19:3235\u20133249. doi: 10.1093\/emboj\/19.13.3235","journal-title":"EMBO J"},{"key":"7_CR6","doi-asserted-by":"publisher","first-page":"516","DOI":"10.4049\/jimmunol.1200064","volume":"189","author":"A Biswas","year":"2012","unstructured":"Biswas A, Meissner TB, Kawai T, Kobayashi KS (2012) Cutting edge: impaired MHC class I expression in mice deficient for Nlrc5\/class I transactivator. J Immunol 189:516\u2013520. doi: 10.4049\/jimmunol.1200064","journal-title":"J Immunol"},{"key":"7_CR7","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1073\/pnas.0609672104","volume":"104","author":"IG Boneca","year":"2007","unstructured":"Boneca IG, Dussurget O, Cabanes D et al (2007) A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system. Proc Natl Acad Sci USA 104:997\u20131002. doi: 10.1073\/pnas.0609672104","journal-title":"Proc Natl Acad Sci USA"},{"key":"7_CR8","doi-asserted-by":"publisher","first-page":"5508","DOI":"10.4049\/jimmunol.1202121","volume":"189","author":"L Bossaller","year":"2012","unstructured":"Bossaller L, Chiang P-I, Schmidt-Lauber C et al (2012) Cutting edge: FAS (CD95) mediates noncanonical IL-1\u03b2 and IL-18 maturation via caspase-8 in an RIP3-independent manner. J Immunol 189:5508\u20135512. doi: 10.4049\/jimmunol.1202121","journal-title":"J Immunol"},{"key":"7_CR9","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1016\/j.chom.2010.04.009","volume":"7","author":"IE Brodsky","year":"2010","unstructured":"Brodsky IE, Palm NW, Sadanand S et al (2010) A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system. Cell Host Microbe 7:376\u2013387. doi: 10.1016\/j.chom.2010.04.009","journal-title":"Cell Host Microbe"},{"key":"7_CR10","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1016\/j.chom.2010.11.007","volume":"8","author":"P Broz","year":"2010","unstructured":"Broz P, von Moltke J, Jones JW et al (2010) Differential requirement for caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing. Cell Host Microbe 8:471\u2013483. doi: 10.1016\/j.chom.2010.11.007","journal-title":"Cell Host Microbe"},{"key":"7_CR001","doi-asserted-by":"publisher","unstructured":"Burke TP, Loukitcheva A, Zemansky J, et al (2014) Listeria monocytogenes is resistant to lysozyme through the regulation, not the acquisition, of cell wall-modifying enzymes. J Bacteriol 196:3756\u20133767. doi: 10.1128\/JB.02053-14","DOI":"10.1128\/JB.02053-14"},{"key":"7_CR11","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1084\/jem.173.3.751","volume":"173","author":"A Camilli","year":"1991","unstructured":"Camilli A, Goldfine H, Portnoy DA (1991) Listeria monocytogenes mutants lacking phosphatidylinositol-specific phospholipase C are avirulent. J Exp Med 173:751\u2013754","journal-title":"J Exp Med"},{"key":"7_CR12","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1084\/jem.20060045","volume":"203","author":"JA Carrero","year":"2006","unstructured":"Carrero JA, Calderon B, Unanue ER (2006) Lymphocytes are detrimental during the early innate immune response against Listeria monocytogenes. J Exp Med 203:933\u2013940. doi: 10.1084\/jem.20060045","journal-title":"J Exp Med"},{"key":"7_CR13","doi-asserted-by":"publisher","first-page":"7187","DOI":"10.4049\/jimmunol.1100412","volume":"186","author":"GY Chen","year":"2011","unstructured":"Chen GY, Liu M, Wang F et al (2011) A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. J Immunol 186:7187\u20137194. doi: 10.4049\/jimmunol.1100412","journal-title":"J Immunol"},{"key":"7_CR14","doi-asserted-by":"publisher","first-page":"3481","DOI":"10.1073\/pnas.1121286109","volume":"109","author":"EA Creasey","year":"2012","unstructured":"Creasey EA, Isberg RR (2012) The protein SdhA maintains the integrity of the Legionella-containing vacuole. Proc Natl Acad Sci USA 109:3481\u20133486. doi: 10.1073\/pnas.1121286109","journal-title":"Proc Natl Acad Sci USA"},{"key":"7_CR15","doi-asserted-by":"publisher","first-page":"1333","DOI":"10.4049\/jimmunol.1003111","volume":"186","author":"BK Davis","year":"2011","unstructured":"Davis BK, Roberts RA, Huang MT et al (2011) Cutting edge: NLRC5-dependent activation of the inflammasome. J Immunol 186:1333\u20131337. doi: 10.4049\/jimmunol.1003111","journal-title":"J Immunol"},{"key":"7_CR16","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1038\/sj.onc.1201206","volume":"15","author":"KL DeYoung","year":"1997","unstructured":"DeYoung KL, Ray ME, Su YA et al (1997) Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma. Oncogene 15:453\u2013457. doi: 10.1038\/sj.onc.1201206","journal-title":"Oncogene"},{"key":"7_CR17","doi-asserted-by":"publisher","first-page":"1711","DOI":"10.4049\/jimmunol.1000105","volume":"185","author":"A Dunne","year":"2010","unstructured":"Dunne A, Ross PJ, Pospisilova E et al (2010) Inflammasome activation by adenylate cyclase toxin directs Th17 responses and protection against Bordetella pertussis. J Immunol 185:1711\u20131719. doi: 10.4049\/jimmunol.1000105","journal-title":"J Immunol"},{"key":"7_CR18","doi-asserted-by":"publisher","first-page":"745","DOI":"10.1016\/j.cell.2011.04.022","volume":"145","author":"E Elinav","year":"2011","unstructured":"Elinav E, Strowig T, Kau AL et al (2011) NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 145:745\u2013757. doi: 10.1016\/j.cell.2011.04.022","journal-title":"Cell"},{"key":"7_CR19","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1038\/nature07710","volume":"458","author":"T Fernandes-Alnemri","year":"2009","unstructured":"Fernandes-Alnemri T, Yu J-W, Datta P et al (2009) AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 458:509\u2013513. doi: 10.1038\/nature07710","journal-title":"Nature"},{"key":"7_CR20","doi-asserted-by":"publisher","first-page":"3995","DOI":"10.4049\/jimmunol.1301681","volume":"191","author":"T Fernandes-Alnemri","year":"2013","unstructured":"Fernandes-Alnemri T, Kang S, Anderson C et al (2013) Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome. J Immunol 191:3995\u20133999. doi: 10.4049\/jimmunol.1301681","journal-title":"J Immunol"},{"key":"7_CR21","doi-asserted-by":"publisher","first-page":"150","DOI":"10.4315\/0362-028X.JFP-13-150","volume":"77","author":"V Ferreira","year":"2014","unstructured":"Ferreira V, Wiedmann M, Teixeira P, Stasiewicz MJ (2014) Listeria monocytogenes persistence in food-associated environments: epidemiology, strain characteristics, and implications for public health. J Food Prot 77:150\u2013170. doi: 10.4315\/0362-028X.JFP-13-150","journal-title":"J Food Prot"},{"key":"7_CR22","doi-asserted-by":"publisher","first-page":"18810","DOI":"10.1074\/jbc.M610762200","volume":"282","author":"L Franchi","year":"2007","unstructured":"Franchi L, Kanneganti T-D, Dubyak GR, N\u00fa\u00f1ez G (2007) Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria. J Biol Chem 282:18810\u201318818. doi: 10.1074\/jbc.M610762200","journal-title":"J Biol Chem"},{"key":"7_CR23","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1006\/mpat.1995.0032","volume":"18","author":"CG Gahan","year":"1995","unstructured":"Gahan CG, Collins JK (1995) Non-dystrophic 129 REJ mice are susceptible to i.p. infection with Listeria monocytogenes despite an ability to recruit inflammatory neutrophils to the peritoneal cavity. Microb Pathog 18:355\u2013364. doi: 10.1006\/mpat.1995.0032","journal-title":"Microb Pathog"},{"key":"7_CR24","doi-asserted-by":"publisher","first-page":"6193","DOI":"10.1073\/pnas.1117490109","volume":"109","author":"J Ge","year":"2012","unstructured":"Ge J, Gong Y-N, Xu Y, Shao F (2012) Preventing bacterial DNA release and absent in melanoma 2 inflammasome activation by a Legionella effector functioning in membrane trafficking. Proc Natl Acad Sci USA 109:6193\u20136198. doi: 10.1073\/pnas.1117490109","journal-title":"Proc Natl Acad Sci USA"},{"key":"7_CR25","doi-asserted-by":"crossref","first-page":"3364","DOI":"10.4049\/jimmunol.159.7.3364","volume":"159","author":"MB Glaccum","year":"1997","unstructured":"Glaccum MB, Stocking KL, Charrier K et al (1997) Phenotypic and functional characterization of mice that lack the type I receptor for IL-1. J Immunol 159:3364\u20133371","journal-title":"J Immunol"},{"key":"7_CR26","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1083\/jcb.200201081","volume":"156","author":"IJ Glomski","year":"2002","unstructured":"Glomski IJ, Gedde MM, Tsang AW et al (2002) The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells. J Cell Biol 156:1029\u20131038. doi: 10.1083\/jcb.200201081","journal-title":"J Cell Biol"},{"key":"7_CR27","doi-asserted-by":"publisher","first-page":"6754","DOI":"10.1128\/IAI.71.12.6754-6765.2003","volume":"71","author":"IJ Glomski","year":"2003","unstructured":"Glomski IJ, Decatur AL, Portnoy DA (2003) Listeria monocytogenes mutants that fail to compartmentalize Listerolysin O activity are cytotoxic, avirulent, and unable to evade host extracellular defenses. Infect Immun 71:6754\u20136765. doi: 10.1128\/IAI.71.12.6754-6765.2003","journal-title":"Infect Immun"},{"key":"7_CR28","doi-asserted-by":"publisher","first-page":"12221","DOI":"10.1073\/pnas.211106398","volume":"98","author":"M Goetz","year":"2001","unstructured":"Goetz M, Bubert A, Wang G et al (2001) Microinjection and growth of bacteria in the cytosol of mammalian host cells. Proc Natl Acad Sci USA 98:12221\u201312226. doi: 10.1073\/pnas.211106398","journal-title":"Proc Natl Acad Sci USA"},{"key":"7_CR29","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1093\/intimm\/4.12.1413","volume":"4","author":"PL Goossens","year":"1992","unstructured":"Goossens PL, Milon G (1992) Induction of protective CD8+ T lymphocytes by an attenuated Listeria monocytogenes actA mutant. Int Immunol 4:1413\u20131418","journal-title":"Int Immunol"},{"key":"7_CR30","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1038\/ni.2222","volume":"13","author":"SI Gringhuis","year":"2012","unstructured":"Gringhuis SI, Kaptein TM, Wevers BA et al (2012) Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1\u03b2 via a noncanonical caspase-8 inflammasome. Nat Immunol 13:246\u2013254. doi: 10.1038\/ni.2222","journal-title":"Nat Immunol"},{"key":"7_CR31","doi-asserted-by":"publisher","first-page":"2839","DOI":"10.1128\/IAI.01243-10","volume":"79","author":"MA Hamon","year":"2011","unstructured":"Hamon MA, Cossart P (2011) K+ efflux is required for histone H3 dephosphorylation by Listeria monocytogenes listeriolysin O and other pore-forming toxins. Infect Immun 79:2839\u20132846. doi: 10.1128\/IAI.01243-10","journal-title":"Infect Immun"},{"key":"7_CR32","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1016\/j.tim.2012.04.006","volume":"20","author":"MA Hamon","year":"2012","unstructured":"Hamon MA, Ribet D, Stavru F, Cossart P (2012) Listeriolysin O: the Swiss army knife of Listeria. Trends Microbiol 20:360\u2013368. doi: 10.1016\/j.tim.2012.04.006","journal-title":"Trends Microbiol"},{"key":"7_CR33","doi-asserted-by":"crossref","first-page":"7859","DOI":"10.4049\/jimmunol.180.12.7859","volume":"180","author":"H Hara","year":"2008","unstructured":"Hara H, Tsuchiya K, Nomura T et al (2008) Dependency of caspase-1 activation induced in macrophages by Listeria monocytogenes on cytolysin, listeriolysin O, after evasion from phagosome into the cytoplasm. J Immunol 180:7859\u20137868","journal-title":"J Immunol"},{"key":"7_CR34","doi-asserted-by":"publisher","first-page":"1894","DOI":"10.1128\/IAI.01315-08","volume":"77","author":"JS Haring","year":"2009","unstructured":"Haring JS, Harty JT (2009) Interleukin-18-related genes are induced during the contraction phase but do not play major roles in regulating the dynamics or function of the T-cell response to Listeria monocytogenes infection. Infect Immun 77:1894\u20131903. doi: 10.1128\/IAI.01315-08","journal-title":"Infect Immun"},{"key":"7_CR35","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1038\/nature07725","volume":"458","author":"V Hornung","year":"2009","unstructured":"Hornung V, Ablasser A, Charrel-Dennis M et al (2009) AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 458:514\u2013518. doi: 10.1038\/nature07725","journal-title":"Nature"},{"issue":"Pt 1","key":"7_CR36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1101\/SQB.1989.054.01.003","volume":"54","author":"CA Janeway","year":"1989","unstructured":"Janeway CA (1989) Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb Symp Quant Biol 54(Pt 1):1\u201313","journal-title":"Cold Spring Harb Symp Quant Biol"},{"key":"7_CR37","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1111\/j.1365-2958.2009.06874.x","volume":"74","author":"HD Kamp","year":"2009","unstructured":"Kamp HD, Higgins DE (2009) Transcriptional and post-transcriptional regulation of the GmaR antirepressor governs temperature-dependent control of flagellar motility in Listeria monocytogenes. Mol Microbiol 74:421\u2013435. doi: 10.1111\/j.1365-2958.2009.06874.x","journal-title":"Mol Microbiol"},{"key":"7_CR38","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1038\/nature04517","volume":"440","author":"T-D Kanneganti","year":"2006","unstructured":"Kanneganti T-D, Oz\u00f6ren N, Body-Malapel M et al (2006) Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin\/Nalp3. Nature 440:233\u2013236. doi: 10.1038\/nature04517","journal-title":"Nature"},{"key":"7_CR39","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1038\/nature10558","volume":"479","author":"N Kayagaki","year":"2011","unstructured":"Kayagaki N, Warming S, Lamkanfi M et al (2011) Non-canonical inflammasome activation targets caspase-11. Nature 479:117\u2013121. doi: 10.1038\/nature10558","journal-title":"Nature"},{"key":"7_CR40","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1038\/nature15541","volume":"526","author":"N Kayagaki","year":"2015","unstructured":"Kayagaki N, Stowe IB, Lee BL et al (2015) Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. Nature 526:666\u2013671. doi: 10.1038\/nature15541","journal-title":"Nature"},{"key":"7_CR41","doi-asserted-by":"publisher","first-page":"1545","DOI":"10.1002\/eji.201040425","volume":"40","author":"S Kim","year":"2010","unstructured":"Kim S, Bauernfeind F, Ablasser A et al (2010) Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome. Eur J Immunol 40:1545\u20131551. doi: 10.1002\/eji.201040425","journal-title":"Eur J Immunol"},{"key":"7_CR42","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/0092-8674(92)90188-I","volume":"68","author":"C Kocks","year":"1992","unstructured":"Kocks C, Gouin E, Tabouret M et al (1992) L. monocytogenes-induced actin assembly requires the actA gene product, a surface protein. Cell 68:521\u2013531","journal-title":"Cell"},{"key":"7_CR43","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1038\/nature10394","volume":"477","author":"EM Kofoed","year":"2011","unstructured":"Kofoed EM, Vance RE (2011) Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature 477:592\u2013595. doi: 10.1038\/nature10394","journal-title":"Nature"},{"key":"7_CR44","doi-asserted-by":"publisher","first-page":"815","DOI":"10.4049\/jimmunol.1403100","volume":"195","author":"J Kortmann","year":"2015","unstructured":"Kortmann J, Brubaker SW, Monack DM (2015) Cutting edge: inflammasome activation in primary human macrophages is dependent on flagellin. J Immunol 195:815\u2013819. doi: 10.4049\/jimmunol.1403100","journal-title":"J Immunol"},{"key":"7_CR45","doi-asserted-by":"crossref","first-page":"2452","DOI":"10.4049\/jimmunol.159.5.2452","volume":"159","author":"M Labow","year":"1997","unstructured":"Labow M, Shuster D, Zetterstrom M et al (1997) Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice. J Immunol 159:2452\u20132461","journal-title":"J Immunol"},{"key":"7_CR46","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1038\/nri3452","volume":"13","author":"E Latz","year":"2013","unstructured":"Latz E, Xiao TS, Stutz A (2013) Activation and regulation of the inflammasomes. Nat Rev Immunol 13:397\u2013411. doi: 10.1038\/nri3452","journal-title":"Nat Rev Immunol"},{"key":"7_CR47","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1053\/j.seminoncol.2012.02.008","volume":"39","author":"DT Le","year":"2012","unstructured":"Le DT, Dubensky TW, Brockstedt DG (2012) Clinical development of Listeria monocytogenes-based immunotherapies. Semin Oncol 39:311\u2013322. doi: 10.1053\/j.seminoncol.2012.02.008","journal-title":"Semin Oncol"},{"key":"7_CR48","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.1200\/JCO.2014.57.4244","volume":"33","author":"DT Le","year":"2015","unstructured":"Le DT, Wang-Gillam A, Picozzi V et al (2015) Safety and survival with GVAX pancreas prime and Listeria monocytogenes-expressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer. J Clin Oncol 33:1325\u20131333. doi: 10.1200\/JCO.2014.57.4244","journal-title":"J Clin Oncol"},{"key":"7_CR49","doi-asserted-by":"publisher","first-page":"e6","DOI":"10.1371\/journal.ppat.0040006","volume":"4","author":"JH Leber","year":"2008","unstructured":"Leber JH, Crimmins GT, Raghavan S et al (2008) Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen. PLoS Pathog 4:e6. doi: 10.1371\/journal.ppat.0040006","journal-title":"PLoS Pathog"},{"key":"7_CR50","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1073\/pnas.1320294111","volume":"111","author":"K-M Lin","year":"2014","unstructured":"Lin K-M, Hu W, Troutman TD et al (2014) IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation. Proc Natl Acad Sci USA 111:775\u2013780. doi: 10.1073\/pnas.1320294111","journal-title":"Proc Natl Acad Sci USA"},{"key":"7_CR51","doi-asserted-by":"publisher","first-page":"3881","DOI":"10.1128\/IAI.01651-07","volume":"76","author":"M Lochner","year":"2008","unstructured":"Lochner M, Kastenm\u00fcller K, Neuenhahn M et al (2008) Decreased susceptibility of mice to infection with Listeria monocytogenes in the absence of interleukin-18. Infect Immun 76:3881\u20133890. doi: 10.1128\/IAI.01651-07","journal-title":"Infect Immun"},{"key":"7_CR52","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1038\/nature04515","volume":"440","author":"S Mariathasan","year":"2006","unstructured":"Mariathasan S, Weiss DS, Newton K et al (2006) Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440:228\u2013232. doi: 10.1038\/nature04515","journal-title":"Nature"},{"key":"7_CR53","doi-asserted-by":"publisher","first-page":"13794","DOI":"10.1073\/pnas.1008684107","volume":"107","author":"TB Meissner","year":"2010","unstructured":"Meissner TB, Li A, Biswas A et al (2010) NLR family member NLRC5 is a transcriptional regulator of MHC class I genes. Proc Natl Acad Sci USA 107:13794\u201313799. doi: 10.1073\/pnas.1008684107","journal-title":"Proc Natl Acad Sci USA"},{"key":"7_CR54","doi-asserted-by":"publisher","first-page":"922","DOI":"10.4049\/jimmunol.0901346","volume":"184","author":"K Meixenberger","year":"2010","unstructured":"Meixenberger K, Pache F, Eitel J et al (2010) Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3. J Immunol 184:922\u2013930. doi: 10.4049\/jimmunol.0901346","journal-title":"J Immunol"},{"key":"7_CR55","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1111\/j.1365-2958.1991.tb02118.x","volume":"5","author":"J Mengaud","year":"1991","unstructured":"Mengaud J, Braun-Breton C, Cossart P (1991) Identification of phosphatidylinositol-specific phospholipase C activity in Listeria monocytogenes: a novel type of virulence factor? Mol Microbiol 5:367\u2013372","journal-title":"Mol Microbiol"},{"key":"7_CR56","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/S0092-8674(00)81070-3","volume":"84","author":"J Mengaud","year":"1996","unstructured":"Mengaud J, Ohayon H, Gounon P et al (1996) E-cadherin is the receptor for internalin, a surface protein required for entry of L. monocytogenes into epithelial cells. Cell 84:923\u2013932","journal-title":"Cell"},{"key":"7_CR57","doi-asserted-by":"crossref","first-page":"6833","DOI":"10.4049\/jimmunol.165.12.6833","volume":"165","author":"R Mercado","year":"2000","unstructured":"Mercado R, Vijh S, Allen SE et al (2000) Early programming of T cell populations responding to bacterial infection. J Immunol 165:6833\u20136839","journal-title":"J Immunol"},{"key":"7_CR58","doi-asserted-by":"publisher","first-page":"1136","DOI":"10.1038\/ni.1960","volume":"11","author":"EA Miao","year":"2010","unstructured":"Miao EA, Leaf IA, Treuting PM et al (2010a) Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria. Nat Immunol 11:1136\u20131142. doi: 10.1038\/ni.1960","journal-title":"Nat Immunol"},{"key":"7_CR59","doi-asserted-by":"publisher","first-page":"3076","DOI":"10.1073\/pnas.0913087107","volume":"107","author":"EA Miao","year":"2010","unstructured":"Miao EA, Mao DP, Yudkovsky N et al (2010b) Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc Natl Acad Sci USA 107:3076\u20133080. doi: 10.1073\/pnas.0913087107","journal-title":"Proc Natl Acad Sci USA"},{"key":"7_CR60","doi-asserted-by":"publisher","first-page":"7984","DOI":"10.4049\/jimmunol.0901336","volume":"183","author":"LA Mielke","year":"2009","unstructured":"Mielke LA, Elkins KL, Wei L et al (2009) Tumor progression locus 2 (Map3k8) is critical for host defense against Listeria monocytogenes and IL-1 beta production. J Immunol 183:7984\u20137993. doi: 10.4049\/jimmunol.0901336","journal-title":"J Immunol"},{"key":"7_CR61","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1084\/jem.194.3.343","volume":"194","author":"M Neighbors","year":"2001","unstructured":"Neighbors M, Xu X, Barrat FJ et al (2001) A critical role for interleukin 18 in primary and memory effector responses to Listeria monocytogenes that extends beyond its effects on interferon production. J Exp Med 194:343\u2013354","journal-title":"J Exp Med"},{"key":"7_CR62","doi-asserted-by":"publisher","first-page":"9601","DOI":"10.1073\/pnas.1100981108","volume":"108","author":"S Normand","year":"2011","unstructured":"Normand S, Delanoye-Crespin A, Bressenot A et al (2011) Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury. Proc Natl Acad Sci USA 108:9601\u20139606. doi: 10.1073\/pnas.1100981108","journal-title":"Proc Natl Acad Sci USA"},{"key":"7_CR63","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1084\/jem.20040712","volume":"200","author":"RM O\u2019Connell","year":"2004","unstructured":"O\u2019Connell RM, Saha SK, Vaidya SA et al (2004) Type I interferon production enhances susceptibility to Listeria monocytogenes infection. J Exp Med 200:437\u2013445. doi: 10.1084\/jem.20040712","journal-title":"J Exp Med"},{"key":"7_CR64","doi-asserted-by":"publisher","first-page":"13861","DOI":"10.1073\/pnas.202476699","volume":"99","author":"M O\u2019Riordan","year":"2002","unstructured":"O\u2019Riordan M, Yi CH, Gonzales R et al (2002) Innate recognition of bacteria by a macrophage cytosolic surveillance pathway. Proc Natl Acad Sci 99:13861\u201313866. doi: 10.1073\/pnas.202476699","journal-title":"Proc Natl Acad Sci"},{"key":"7_CR65","doi-asserted-by":"crossref","first-page":"484","DOI":"10.4049\/jimmunol.176.1.484","volume":"176","author":"B Opitz","year":"2006","unstructured":"Opitz B, P\u00fcschel A, Beermann W et al (2006) Listeria monocytogenes activated p38 MAPK and induced IL-8 secretion in a nucleotide-binding oligomerization domain 1-dependent manner in endothelial cells. J Immunol 176:484\u2013490","journal-title":"J Immunol"},{"key":"7_CR66","doi-asserted-by":"crossref","first-page":"4337","DOI":"10.4049\/jimmunol.176.7.4337","volume":"176","author":"N Oz\u00f6ren","year":"2006","unstructured":"Oz\u00f6ren N, Masumoto J, Franchi L et al (2006) Distinct roles of TLR2 and the adaptor ASC in IL-1beta\/IL-18 secretion in response to Listeria monocytogenes. J Immunol 176:4337\u20134342","journal-title":"J Immunol"},{"key":"7_CR67","doi-asserted-by":"publisher","first-page":"2171","DOI":"10.1099\/00221287-134-8-2171","volume":"134","author":"M Peel","year":"1988","unstructured":"Peel M, Donachie W, Shaw A (1988) Temperature-dependent expression of flagella of Listeria monocytogenes studied by electron microscopy, SDS-PAGE and western blotting. J Gen Microbiol 134:2171\u20132178. doi: 10.1099\/00221287-134-8-2171","journal-title":"J Gen Microbiol"},{"key":"7_CR68","doi-asserted-by":"publisher","first-page":"1586","DOI":"10.1111\/j.1462-5822.2011.01643.x","volume":"13","author":"K Peng","year":"2011","unstructured":"Peng K, Broz P, Jones J et al (2011) Elevated AIM2-mediated pyroptosis triggered by hypercytotoxic Francisella mutant strains is attributed to increased intracellular bacteriolysis. Cell Microbiol 13:1586\u20131600. doi: 10.1111\/j.1462-5822.2011.01643.x","journal-title":"Cell Microbiol"},{"key":"7_CR69","doi-asserted-by":"publisher","first-page":"1979","DOI":"10.1128\/IAI.01096-09","volume":"78","author":"N Personnic","year":"2010","unstructured":"Personnic N, Bruck S, Nahori M-A et al (2010) The stress-induced virulence protein InlH controls interleukin-6 production during murine listeriosis. Infect Immun 78:1979\u20131989. doi: 10.1128\/IAI.01096-09","journal-title":"Infect Immun"},{"key":"7_CR70","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1084\/jem.167.4.1459","volume":"167","author":"DA Portnoy","year":"1988","unstructured":"Portnoy DA, Jacks PS, Hinrichs DJ (1988) Role of hemolysin for the intracellular growth of Listeria monocytogenes. J Exp Med 167:1459\u20131471","journal-title":"J Exp Med"},{"key":"7_CR71","doi-asserted-by":"publisher","first-page":"3596","DOI":"10.1128\/IAI.00077-11","volume":"79","author":"CS Rae","year":"2011","unstructured":"Rae CS, Geissler A, Adamson PC, Portnoy DA (2011) Mutations of the Listeria monocytogenes peptidoglycan N-deacetylase and O-acetylase result in enhanced lysozyme sensitivity, bacteriolysis, and hyperinduction of innate immune pathways. Infect Immun 79:3596\u20133606. doi: 10.1128\/IAI.00077-11","journal-title":"Infect Immun"},{"key":"7_CR72","doi-asserted-by":"publisher","first-page":"20459","DOI":"10.1073\/pnas.1010337107","volume":"107","author":"M Ritter","year":"2010","unstructured":"Ritter M, Gross O, Kays S et al (2010) Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses. Proc Natl Acad Sci USA 107:20459\u201320464. doi: 10.1073\/pnas.1010337107","journal-title":"Proc Natl Acad Sci USA"},{"key":"7_CR73","doi-asserted-by":"publisher","first-page":"e75911","DOI":"10.1371\/journal.pone.0075911","volume":"8","author":"OS Sakhon","year":"2013","unstructured":"Sakhon OS, Victor KA, Choy A et al (2013) NSD1 mitigates caspase-1 activation by listeriolysin O in macrophages. PLoS ONE 8:e75911. doi: 10.1371\/journal.pone.0075911","journal-title":"PLoS ONE"},{"key":"7_CR74","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1016\/j.chom.2010.04.004","volume":"7","author":"J-D Sauer","year":"2010","unstructured":"Sauer J-D, Witte CE, Zemansky J et al (2010) Listeria monocytogenes triggers AIM2-mediated pyroptosis upon infrequent bacteriolysis in the macrophage cytosol. Cell Host Microbe 7:412\u2013419. doi: 10.1016\/j.chom.2010.04.004","journal-title":"Cell Host Microbe"},{"key":"7_CR75","doi-asserted-by":"publisher","first-page":"12419","DOI":"10.1073\/pnas.1019041108","volume":"108","author":"J-D Sauer","year":"2011","unstructured":"Sauer J-D, Pereyre S, Archer KA et al (2011a) Listeria monocytogenes engineered to activate the Nlrc4 inflammasome are severely attenuated and are poor inducers of protective immunity. Proc Natl Acad Sci USA 108:12419\u201312424. doi: 10.1073\/pnas.1019041108","journal-title":"Proc Natl Acad Sci USA"},{"key":"7_CR76","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1128\/IAI.00999-10","volume":"79","author":"J-D Sauer","year":"2011","unstructured":"Sauer J-D, Sotelo-Troha K, von Moltke J et al (2011b) The N-ethyl-N-nitrosourea-induced Goldenticket mouse mutant reveals an essential function of Sting in the in vivo interferon response to Listeria monocytogenes and cyclic dinucleotides. Infect Immun 79:688\u2013694. doi: 10.1128\/IAI.00999-10","journal-title":"Infect Immun"},{"key":"7_CR77","doi-asserted-by":"publisher","first-page":"e45186","DOI":"10.1371\/journal.pone.0045186","volume":"7","author":"RL Schmidt","year":"2012","unstructured":"Schmidt RL, Lenz LL (2012) Distinct licensing of IL-18 and IL-1\u03b2 secretion in response to NLRP3 inflammasome activation. PLoS ONE 7:e45186. doi: 10.1371\/journal.pone.0045186","journal-title":"PLoS ONE"},{"key":"7_CR78","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1111\/j.1365-2958.2006.05286.x","volume":"61","author":"P Schnupf","year":"2006","unstructured":"Schnupf P, Hofmann J, Norseen J et al (2006a) Regulated translation of listeriolysin O controls virulence of Listeria monocytogenes. Mol Microbiol 61:999\u20131012. doi: 10.1111\/j.1365-2958.2006.05286.x","journal-title":"Mol Microbiol"},{"key":"7_CR79","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1111\/j.1462-5822.2005.00631.x","volume":"8","author":"P Schnupf","year":"2006","unstructured":"Schnupf P, Portnoy DA, Decatur AL (2006b) Phosphorylation, ubiquitination and degradation of listeriolysin O in mammalian cells: role of the PEST-like sequence. Cell Microbiol 8:353\u2013364. doi: 10.1111\/j.1462-5822.2005.00631.x","journal-title":"Cell Microbiol"},{"key":"7_CR80","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.1111\/j.1365-2958.2005.04780.x","volume":"57","author":"A Shen","year":"2005","unstructured":"Shen A, Higgins DE (2005) The 5\u2019 untranslated region-mediated enhancement of intracellular listeriolysin O production is required for Listeria monocytogenes pathogenicity. Mol Microbiol 57:1460\u20131473. doi: 10.1111\/j.1365-2958.2005.04780.x","journal-title":"Mol Microbiol"},{"key":"7_CR81","doi-asserted-by":"publisher","first-page":"e30","DOI":"10.1371\/journal.ppat.0020030","volume":"2","author":"A Shen","year":"2006","unstructured":"Shen A, Higgins DE (2006) The MogR transcriptional repressor regulates nonhierarchal expression of flagellar motility genes and virulence in Listeria monocytogenes. PLoS Pathog 2:e30. doi: 10.1371\/journal.ppat.0020030","journal-title":"PLoS Pathog"},{"key":"7_CR82","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/S0092-8674(00)00141-0","volume":"103","author":"Y Shen","year":"2000","unstructured":"Shen Y, Naujokas M, Park M, Ireton K (2000) InlB-dependent internalization of Listeria is mediated by the met receptor tyrosine kinase. Cell 103:501\u2013510. doi: 10.1016\/S0092-8674(00)00141-0","journal-title":"Cell"},{"key":"7_CR83","doi-asserted-by":"publisher","first-page":"3283","DOI":"10.1101\/gad.1492606","volume":"20","author":"A Shen","year":"2006","unstructured":"Shen A, Kamp HD, Grundling A, Higgins DE (2006) A bifunctional O-GlcNAc transferase governs flagellar motility through anti-repression. Genes Dev 20:3283\u20133295. doi: 10.1101\/gad.1492606","journal-title":"Genes Dev"},{"key":"7_CR84","doi-asserted-by":"publisher","first-page":"5293","DOI":"10.4049\/jimmunol.1101721","volume":"187","author":"C Shi","year":"2011","unstructured":"Shi C, Hohl TM, Leiner I et al (2011) Ly6G+ neutrophils are dispensable for defense against systemic Listeria monocytogenes infection. J Immunol 187:5293\u20135298. doi: 10.4049\/jimmunol.1101721","journal-title":"J Immunol"},{"key":"7_CR85","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1038\/nature15514","volume":"526","author":"J Shi","year":"2015","unstructured":"Shi J, Zhao Y, Wang K et al (2015) Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature 526:660\u2013665. doi: 10.1038\/nature15514","journal-title":"Nature"},{"key":"7_CR86","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1086\/381206","volume":"189","author":"J Slaghuis","year":"2004","unstructured":"Slaghuis J, Goetz M, Engelbrecht F, Goebel W (2004) Inefficient replication of Listeria innocua in the cytosol of mammalian cells. J Infect Dis 189:393\u2013401. doi: 10.1086\/381206","journal-title":"J Infect Dis"},{"key":"7_CR87","doi-asserted-by":"crossref","first-page":"6568","DOI":"10.4049\/jimmunol.167.11.6568","volume":"167","author":"S Sugawara","year":"2001","unstructured":"Sugawara S, Uehara A, Nochi T et al (2001) Neutrophil proteinase 3-mediated induction of bioactive IL-18 secretion by human oral epithelial cells. J Immunol 167:6568\u20136575","journal-title":"J Immunol"},{"key":"7_CR88","doi-asserted-by":"publisher","first-page":"3235","DOI":"10.1084\/jem.20071239","volume":"204","author":"FS Sutterwala","year":"2007","unstructured":"Sutterwala FS, Mijares LA, Li L et al (2007) Immune recognition of Pseudomonas aeruginosa mediated by the IPAF\/NLRC4 inflammasome. J Exp Med 204:3235\u20133245. doi: 10.1084\/jem.20071239","journal-title":"J Exp Med"},{"key":"7_CR89","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1016\/j.micinf.2007.05.011","volume":"9","author":"B Swaminathan","year":"2007","unstructured":"Swaminathan B, Gerner-Smidt P (2007) The epidemiology of human listeriosis. Microbes Infect 9:1236\u20131243. doi: 10.1016\/j.micinf.2007.05.011","journal-title":"Microbes Infect"},{"key":"7_CR90","doi-asserted-by":"crossref","first-page":"978","DOI":"10.4049\/jimmunol.163.2.978","volume":"163","author":"JA Thomas","year":"1999","unstructured":"Thomas JA, Allen JL, Tsen M et al (1999) Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase. J Immunol 163:978\u2013984","journal-title":"J Immunol"},{"key":"7_CR91","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.4049\/jimmunol.1001058","volume":"185","author":"K Tsuchiya","year":"2010","unstructured":"Tsuchiya K, Hara H, Kawamura I et al (2010) Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes. J Immunol 185:1186\u20131195. doi: 10.4049\/jimmunol.1001058","journal-title":"J Immunol"},{"key":"7_CR92","doi-asserted-by":"publisher","first-page":"3696","DOI":"10.1002\/eji.201444673","volume":"44","author":"K Tsuchiya","year":"2014","unstructured":"Tsuchiya K, Hara H, Fang R et al (2014) The adaptor ASC exacerbates lethal Listeria monocytogenes infection by mediating IL-18 production in an inflammasome-dependent and -independent manner. Eur J Immunol 44:3696\u20133707. doi: 10.1002\/eji.201444673","journal-title":"Eur J Immunol"},{"key":"7_CR93","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1093\/intimm\/dxh041","volume":"16","author":"NM Tsuji","year":"2004","unstructured":"Tsuji NM, Tsutsui H, Seki E et al (2004) Roles of caspase-1 in Listeria infection in mice. Int Immunol 16:335\u2013343","journal-title":"Int Immunol"},{"key":"7_CR94","doi-asserted-by":"publisher","first-page":"4245","DOI":"10.4049\/jimmunol.1203059","volume":"190","author":"R Uchiyama","year":"2013","unstructured":"Uchiyama R, Yonehara S, Tsutsui H (2013) Fas-mediated inflammatory response in Listeria monocytogenes infection. J Immunol (Baltimore, Md 1950) 190:4245\u20134254. doi: 10.4049\/jimmunol.1203059","journal-title":"J Immunol (Baltimore, Md 1950)"},{"key":"7_CR95","doi-asserted-by":"publisher","first-page":"2260","DOI":"10.1002\/eji.201041226","volume":"41","author":"FL Veerdonk van de","year":"2011","unstructured":"van de Veerdonk FL, Joosten LAB, Shaw PJ et al (2011) The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis. Eur J Immunol 41:2260\u20132268. doi: 10.1002\/eji.201041226","journal-title":"Eur J Immunol"},{"key":"7_CR96","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1089\/hum.2009.022","volume":"21","author":"JP Pijkeren van","year":"2010","unstructured":"van Pijkeren JP, Morrissey D, Monk IR et al (2010) A novel Listeria monocytogenes-based DNA delivery system for cancer gene therapy. Hum Gene Ther 21:405\u2013416. doi: 10.1089\/hum.2009.022","journal-title":"Hum Gene Ther"},{"key":"7_CR97","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1128\/IAI.60.1.219-230.1992","volume":"60","author":"JA Vazquez-Boland","year":"1992","unstructured":"Vazquez-Boland JA, Kocks C, Dramsi S et al (1992) Nucleotide sequence of the lecithinase operon of Listeria monocytogenes and possible role of lecithinase in cell-to-cell spread. Infect Immun 60:219\u2013230","journal-title":"Infect Immun"},{"key":"7_CR98","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12536","author":"WJB Vincent","year":"2015","unstructured":"Vincent WJB, Freisinger CM, Lam P-Y et al (2015) Macrophages are required for inflammasome-dependent host defense in vivo. Cell Microbiol. doi: 10.1111\/cmi.12536","journal-title":"Cell Microbiol"},{"key":"7_CR99","doi-asserted-by":"publisher","first-page":"e1001326","DOI":"10.1371\/journal.ppat.1001326","volume":"7","author":"JC Waite","year":"2011","unstructured":"Waite JC, Leiner I, Lauer P et al (2011) Dynamic imaging of the effector immune response to listeria infection in vivo. PLoS Pathog 7:e1001326. doi: 10.1371\/journal.ppat.1001326","journal-title":"PLoS Pathog"},{"key":"7_CR100","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/S0092-8674(00)80943-5","volume":"92","author":"S Wang","year":"1998","unstructured":"Wang S, Miura M, Jung YK et al (1998) Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. Cell 92:501\u2013509","journal-title":"Cell"},{"key":"7_CR101","doi-asserted-by":"crossref","first-page":"7558","DOI":"10.4049\/jimmunol.180.11.7558","volume":"180","author":"SE Warren","year":"2008","unstructured":"Warren SE, Mao DP, Rodriguez AE et al (2008) Multiple Nod-like receptors activate caspase 1 during Listeria monocytogenes infection. J Immunol 180:7558\u20137564","journal-title":"J Immunol"},{"key":"7_CR102","doi-asserted-by":"publisher","first-page":"818","DOI":"10.4049\/jimmunol.1000724","volume":"185","author":"SE Warren","year":"2010","unstructured":"Warren SE, Armstrong A, Hamilton MK et al (2010) Cutting edge: cytosolic bacterial DNA activates the inflammasome via Aim2. J Immunol 185:818\u2013821. doi: 10.4049\/jimmunol.1000724","journal-title":"J Immunol"},{"key":"7_CR103","doi-asserted-by":"publisher","first-page":"1934","DOI":"10.1002\/eji.201041214","volume":"41","author":"SE Warren","year":"2011","unstructured":"Warren SE, Duong H, Mao DP et al (2011) Generation of a Listeria vaccine strain by enhanced caspase-1 activation. Eur J Immunol 41:1934\u20131940. doi: 10.1002\/eji.201041214","journal-title":"Eur J Immunol"},{"key":"7_CR104","doi-asserted-by":"publisher","first-page":"e83191","DOI":"10.1371\/journal.pone.0083191","volume":"8","author":"CR Williams","year":"2013","unstructured":"Williams CR, Dustin ML, Sauer J-D (2013) Inflammasome-mediated inhibition of Listeria monocytogenes-stimulated immunity is independent of myelomonocytic function. PLoS ONE 8:e83191. doi: 10.1371\/journal.pone.0083191","journal-title":"PLoS ONE"},{"key":"7_CR105","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/B978-0-12-394590-7.00002-6","volume":"113","author":"CE Witte","year":"2012","unstructured":"Witte CE, Archer KA, Rae CS et al (2012) Innate immune pathways triggered by Listeria monocytogenes and their role in the induction of cell-mediated immunity. Adv Immunol 113:135\u2013156. doi: 10.1016\/B978-0-12-394590-7.00002-6","journal-title":"Adv Immunol"},{"issue":"328","key":"7_CR106","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1126\/science.1189801","volume":"80","author":"JJ Woodward","year":"2010","unstructured":"Woodward JJ, Iavarone AT, Portnoy DA (2010) c-di-AMP secreted by intracellular Listeria monocytogenes activates a host type I interferon response. Science 80(328):1703\u20131705","journal-title":"Science"},{"key":"7_CR107","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1007\/s10875-010-9425-2","volume":"30","author":"J Wu","year":"2010","unstructured":"Wu J, Fernandes-Alnemri T, Alnemri ES (2010) Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in Caspase-1 activation by Listeria monocytogenes. J Clin Immunol 30:693\u2013702. doi: 10.1007\/s10875-010-9425-2","journal-title":"J Clin Immunol"},{"key":"7_CR108","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1038\/cr.2012.56","volume":"22","author":"Y Yao","year":"2012","unstructured":"Yao Y, Wang Y, Chen F et al (2012) NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogens. Cell Res 22:836\u2013847. doi: 10.1038\/cr.2012.56","journal-title":"Cell Res"},{"key":"7_CR109","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1038\/nature10510","volume":"477","author":"Y Zhao","year":"2011","unstructured":"Zhao Y, Yang J, Shi J et al (2011) The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 477:596\u2013600. doi: 10.1038\/nature10510","journal-title":"Nature"},{"key":"7_CR110","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/1074-7613(95)90154-X","volume":"3","author":"H Zheng","year":"1995","unstructured":"Zheng H, Fletcher D, Kozak W et al (1995) Resistance to fever induction and impaired acute-phase response in interleukin-1\u03b2-deficient mice. Immunity 3:9\u201319. doi: 10.1016\/1074-7613(95)90154-X","journal-title":"Immunity"},{"key":"7_CR111","doi-asserted-by":"publisher","first-page":"1526","DOI":"10.1128\/IAI.01195-10","volume":"79","author":"T Zou","year":"2011","unstructured":"Zou T, Garifulin O, Berland R, Boyartchuk VL (2011) Listeria monocytogenes infection induces prosurvival metabolic signaling in macrophages. Infect Immun 79:1526\u20131535. doi: 10.1128\/IAI.01195-10","journal-title":"Infect Immun"}],"container-title":["Current Topics in Microbiology and Immunology","Inflammasome Signaling and Bacterial Infections"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-319-41171-2_7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T10:08:22Z","timestamp":1692439702000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-319-41171-2_7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"ISBN":["9783319411705","9783319411712"],"references-count":112,"URL":"https:\/\/doi.org\/10.1007\/978-3-319-41171-2_7","relation":{},"ISSN":["0070-217X","2196-9965"],"issn-type":[{"value":"0070-217X","type":"print"},{"value":"2196-9965","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}