{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T11:24:52Z","timestamp":1766748292249,"version":"3.41.0"},"publisher-location":"Cham","reference-count":26,"publisher":"Springer International Publishing","isbn-type":[{"type":"print","value":"9783319447773"},{"type":"electronic","value":"9783319447780"}],"license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016]]},"DOI":"10.1007\/978-3-319-44778-0_30","type":"book-chapter","created":{"date-parts":[[2016,8,12]],"date-time":"2016-08-12T15:20:33Z","timestamp":1471015233000},"page":"256-263","source":"Crossref","is-referenced-by-count":2,"title":["Realizing Medium Spiny Neurons with a Simple Neuron Model"],"prefix":"10.1007","author":[{"given":"Sami Utku","family":"\u00c7elikok","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neslihan Serap","family":"\u015eeng\u00f6r","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,8,13]]},"reference":[{"key":"30_CR1","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.1162\/jocn.2006.18.12.1973","volume":"18","author":"R Cools","year":"2006","unstructured":"Cools, R., Ivry, R.B., D\u2019Esposito, M.: The human striatum is necessary for responding to changes in stimulus relevance. J. Cogn. Neurosci. 18, 1973\u20131983 (2006)","journal-title":"J. Cogn. Neurosci."},{"key":"30_CR2","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1002\/1531-8257(200009)15:5<762::AID-MDS1002>3.0.CO;2-2","volume":"15","author":"A Gillies","year":"2000","unstructured":"Gillies, A., Arbuthnott, G.W.: Computational models of the basal ganglia. Mov. Disord. 15, 762\u2013770 (2000)","journal-title":"Mov. Disord."},{"key":"30_CR3","first-page":"53","volume":"67","author":"A Nieoullon","year":"2002","unstructured":"Nieoullon, A.: Dopamine and the regulation of cognition and attention. Neurobiology 67, 53\u201383 (2002)","journal-title":"Neurobiology"},{"key":"30_CR4","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1152\/jn.1992.68.3.945","volume":"68","author":"P Apicella","year":"1992","unstructured":"Apicella, P., et al.: Neuronal activity in monkey striatum related to the expectation of predictable environmental events. J. Neurophysiol. 68, 945\u2013960 (1992)","journal-title":"J. Neurophysiol."},{"key":"30_CR5","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S1471-1931(00)00019-7","volume":"23","author":"CR Gerfen","year":"2000","unstructured":"Gerfen, C.R.: Molecular effects of dopamine on striatal projection pathways. Trends Neurosci. 23, 64\u201370 (2000)","journal-title":"Trends Neurosci."},{"key":"30_CR6","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0920-9964(01)00400-5","volume":"59","author":"MS Keshavan","year":"2003","unstructured":"Keshavan, M.S., et al.: Psychosis proneness and ADHD in young relatives of schizophrenia patients. Schizophr. Res. 59, 85\u201392 (2003)","journal-title":"Schizophr. Res."},{"key":"30_CR7","doi-asserted-by":"crossref","unstructured":"Weiner, I., Joel, D.: Dopamine in schizophrenia: dysfunctional processing in basal ganglia-thalamocortical split circuits. In: Handbook of Experimental Pharmacology: Dopamine in the CNS, vol. 154, pp. 417\u2013471 (2002)","DOI":"10.1007\/978-3-662-06765-9_13"},{"key":"30_CR8","doi-asserted-by":"crossref","first-page":"e1001011","DOI":"10.3389\/neuro.10.026.2009","volume":"3","author":"MD Humphries","year":"2009","unstructured":"Humphries, M.D., et al.: Capturing dopaminergic modulation and bimodal membrane behaviour of striatal medium spiny neurons in accurate, reduced models. Front. Comput. Neurosci 3, e1001011 (2009)","journal-title":"Front. Comput. Neurosci"},{"key":"30_CR9","doi-asserted-by":"crossref","first-page":"3731","DOI":"10.1152\/jn.00335.2007","volume":"98","author":"JT Moyer","year":"2007","unstructured":"Moyer, J.T., Wolf, J.A., Finkel, L.H.: Effects of dopaminergic modulation on the integrative properties of the ventral striatal medium spiny neuron. J. Neurophysiol. 98, 3731\u20133748 (2007)","journal-title":"J. Neurophysiol."},{"key":"30_CR10","unstructured":"Gruber, A.J., Solla, S.A., Houk, J.C.: Dopamine induced bistability enhances signal processing in spiny neurons. In: Advances in Neural Information Processing Systems, vol. 15, pp. 165\u2013172. MIT Press, Cambridge (2003)"},{"key":"30_CR11","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.bbr.2008.12.036","volume":"200","author":"M Guthrie","year":"2009","unstructured":"Guthrie, M., Myers, C.E., Gluck, M.A.: A neurocomputational model of tonic and phasic dopamine in action selection: a comparison with cognitive deficits in Parkinson\u2019s disease. Behav. Brain Res. 200, 48\u201359 (2009)","journal-title":"Behav. Brain Res."},{"key":"30_CR12","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1037\/0735-7044.120.3.497","volume":"120","author":"MJ Frank","year":"2006","unstructured":"Frank, M.J., O\u2019Reilly, R.C.: A mechanistic account of striatal dopamine function in human cognition: psychopharmacological studies with cabergoline and haloperidol. Behav. Neurosci. 120, 497\u2013517 (2006)","journal-title":"Behav. Neurosci."},{"key":"30_CR13","doi-asserted-by":"crossref","unstructured":"Navarro-Lopez, E.M., Celikok, U., Sengor, N.S.: Hybrid Systems Neuroscience. In: El Hady, A. (ed.) Closed-Loop Neuroscience. Academic Press (2016, in press)","DOI":"10.1016\/B978-0-12-802452-2.00009-3"},{"key":"30_CR14","first-page":"236","volume":"76","author":"G Deco","year":"2005","unstructured":"Deco, G., Rolls, E.T.: Attention, short-term memory, and action selection: a unifying theory. Neurobiology 76, 236\u2013256 (2005)","journal-title":"Neurobiology"},{"key":"30_CR15","doi-asserted-by":"crossref","first-page":"10814","DOI":"10.1523\/JNEUROSCI.2660-08.2008","volume":"28","author":"TS Gertler","year":"2008","unstructured":"Gertler, T.S., Chan, C.S., Surmeier, D.J.: Dichotomous anatomical properties of adult striatal medium spiny neurons. J. Neurosci. 28, 10814\u201310824 (2008)","journal-title":"J. Neurosci."},{"key":"30_CR16","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1146\/annurev.neuro.23.1.185","volume":"23","author":"SM Nicola","year":"2000","unstructured":"Nicola, S.M., Surmeier, J., Malenka, R.C.: Dopaminergic modulation of neuronal excitability in the striatum and nucleus accumbens. Annu. Rev. Neurosci. 23, 185\u2013215 (2000)","journal-title":"Annu. Rev. Neurosci."},{"key":"30_CR17","doi-asserted-by":"crossref","first-page":"4449","DOI":"10.1523\/JNEUROSCI.15-06-04449.1995","volume":"15","author":"ES Nisenbaum","year":"1995","unstructured":"Nisenbaum, E.S., Wilson, C.J.: Potassium currents responsible for inward and outward rectification in rat neostriatal spiny projection neurons. J. neurosci. 15, 4449\u20134463 (1995)","journal-title":"J. neurosci."},{"key":"30_CR18","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0026-895X(25)08511-6","volume":"47","author":"CW Lin","year":"1995","unstructured":"Lin, C.W., et al.: Characterization of cloned human dopamine D $$_{1}$$ receptor-mediated calcium release in 293 cells. Mol. Pharmacol. 47, 131\u2013139 (1995)","journal-title":"Mol. Pharmacol."},{"key":"30_CR19","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1111\/j.1476-5381.1994.tb13138.x","volume":"112","author":"GR Seabrook","year":"1994","unstructured":"Seabrook, G.R., et al.: Pharmacology of high-threshold calcium currents in GH $$_{4}$$ C $$_{1}$$ pituitary cells and their regulation by activation of human D $$_{2}$$ and D $$_{4}$$ dopamine receptors. Br. J. Pharmacol. 112, 728\u2013734 (1994)","journal-title":"Br. J. Pharmacol."},{"key":"30_CR20","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1523\/JNEUROSCI.16-07-02397.1996","volume":"16","author":"CJ Wilson","year":"1996","unstructured":"Wilson, C.J., Kawaguchi, Y.: The origins of two-state spontaneous membrane potential fluctuations of neostriatal spiny neurons. J. Neurosci. 16, 2397\u20132410 (1996)","journal-title":"J. Neurosci."},{"key":"30_CR21","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/PL00007984","volume":"84","author":"K Gurney","year":"2001","unstructured":"Gurney, K., Prescott, T.J., Redgrave, P.: A computational model of action selection in the basal ganglia. I. A new functional anatomy. Biol. Cybern. 84, 401\u2013410 (2001)","journal-title":"Biol. Cybern."},{"key":"30_CR22","doi-asserted-by":"crossref","first-page":"9080","DOI":"10.1523\/JNEUROSCI.2220-05.2005","volume":"25","author":"JA Wolf","year":"2005","unstructured":"Wolf, J.A., et al.: NMDA\/AMPA ratio impacts state transitions and entrainment to oscillations in a computational model of the nucleus accumbens medium spiny projection neuron. J. Neurosci. 25, 9080\u20139095 (2005)","journal-title":"J. Neurosci."},{"key":"30_CR23","unstructured":"Elibol, R., Sengor, N.S.: A computational model investigating the role of dopamine on synchronization of striatal medium spiny neurons. In: Medicine Technology Congress, pp. 147\u2013150 (2014)"},{"key":"30_CR24","volume-title":"Dynamical Systems in Neuroscience","author":"EM Izhikevich","year":"2007","unstructured":"Izhikevich, E.M.: Dynamical Systems in Neuroscience. MIT Press, Cambridge (2007)"},{"key":"30_CR25","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1469-7793.2000.t01-1-00345.x","volume":"527","author":"S Mahon","year":"2000","unstructured":"Mahon, S., et al.: Intrinsic properties of rat striatal output neurones and time-dependent facilitation of cortical inputs in vivo. J. Physiol. 527, 345\u2013354 (2000)","journal-title":"J. Physiol."},{"key":"30_CR26","unstructured":"Celikok, U., Navarro-Lopez, E.M., Sengor, N.S.: A Computational Model Describing the Interplay of Basal Ganglia and Subcortical Background Oscillations during Working Memory Processes. arXiv preprint, arXiv:1601.07740 (2016)"}],"container-title":["Lecture Notes in Computer Science","Artificial Neural Networks and Machine Learning \u2013 ICANN 2016"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-319-44778-0_30","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,4]],"date-time":"2025-06-04T17:43:55Z","timestamp":1749059035000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-319-44778-0_30"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"ISBN":["9783319447773","9783319447780"],"references-count":26,"URL":"https:\/\/doi.org\/10.1007\/978-3-319-44778-0_30","relation":{},"ISSN":["0302-9743","1611-3349"],"issn-type":[{"type":"print","value":"0302-9743"},{"type":"electronic","value":"1611-3349"}],"subject":[],"published":{"date-parts":[[2016]]}}}