{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T10:08:57Z","timestamp":1790762937307,"version":"4.1.0"},"publisher-location":"Cham","reference-count":102,"publisher":"Springer International Publishing","isbn-type":[{"value":"9783319601885","type":"print"},{"value":"9783319601892","type":"electronic"}],"license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017]]},"DOI":"10.1007\/978-3-319-60189-2_13","type":"book-chapter","created":{"date-parts":[[2017,9,11]],"date-time":"2017-09-11T13:52:18Z","timestamp":1505137938000},"page":"267-286","source":"Crossref","is-referenced-by-count":60,"title":["Methylmercury-Induced Neurotoxicity: Focus on Pro-oxidative Events and Related Consequences"],"prefix":"10.1007","author":[{"given":"Marcelo","family":"Farina","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Aschner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,9,10]]},"reference":[{"key":"13_CR1","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/j.etap.2016.02.001","volume":"42","author":"IA Adedara","year":"2016","unstructured":"Adedara IA, Rosemberg DB, Souza DO, Farombi EO, Aschner M, Rocha JB. Neuroprotection of luteolin against methylmercury-induced toxicity in lobster cockroach Nauphoeta cinerea. Environ Toxicol Pharmacol. 2016;42:243\u201351. doi: 10.1016\/j.etap.2016.02.001 .","journal-title":"Environ Toxicol Pharmacol"},{"issue":"1","key":"13_CR2","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/S0006-8993(01)02375-7","volume":"902","author":"JW Allen","year":"2001","unstructured":"Allen JW, Mutkus LA, Aschner M. Methylmercury-mediated inhibition of 3H-D-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase. Brain Res. 2001;902(1):92\u2013100.","journal-title":"Brain Res"},{"issue":"4","key":"13_CR3","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/j.1600-0773.1993.tb01563.x","volume":"73","author":"HR Andersen","year":"1993","unstructured":"Andersen HR, Andersen O. Effects of dietary alpha-tocopherol and beta-carotene on lipid peroxidation induced by methyl mercuric chloride in mice. Pharmacol Toxicol. 1993;73(4):192\u2013201.","journal-title":"Pharmacol Toxicol"},{"issue":"12","key":"13_CR4","doi-asserted-by":"publisher","first-page":"4880","DOI":"10.3390\/molecules14124880","volume":"14","author":"H Araie","year":"2009","unstructured":"Araie H, Shiraiwa Y. Selenium utilization strategy by microalgae. Molecules. 2009;14(12):4880\u201391. doi: 10.3390\/molecules14124880 .","journal-title":"Molecules"},{"issue":"1","key":"13_CR5","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0006-8993(88)90581-1","volume":"462","author":"M Aschner","year":"1988","unstructured":"Aschner M, Clarkson TW. Uptake of methylmercury in the rat brain: effects of amino acids. Brain Res. 1988;462(1):31\u20139.","journal-title":"Brain Res"},{"issue":"2\u20133","key":"13_CR6","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0197-0186(00)00023-1","volume":"37","author":"M Aschner","year":"2000","unstructured":"Aschner M, Yao CP, Allen JW, Tan KH. Methylmercury alters glutamate transport in astrocytes. Neurochem Int. 2000;37(2\u20133):199\u2013206.","journal-title":"Neurochem Int"},{"issue":"3","key":"13_CR7","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1590\/S0100-879X2007000300001","volume":"40","author":"M Aschner","year":"2007","unstructured":"Aschner M, Syversen T, Souza DO, Rocha JB, Farina M. Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity. Braz J Med Biol Res. 2007;40(3):285\u201391.","journal-title":"Braz J Med Biol Res"},{"issue":"3","key":"13_CR8","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1046\/j.1525-1373.1999.d01-141.x","volume":"222","author":"AE Aust","year":"1999","unstructured":"Aust AE, Eveleigh JF. Mechanisms of DNA oxidation. Proc Soc Exp Biol Med. 1999;222(3):246\u201352.","journal-title":"Proc Soc Exp Biol Med"},{"issue":"4096","key":"13_CR9","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1126\/science.181.4096.230","volume":"181","author":"F Bakir","year":"1973","unstructured":"Bakir F, Damluji SF, Amin-Zaki L, Murtadha M, Khalidi A, al-Rawi NY, Tikriti S, Dahahir HI, Clarkson TW, Smith JC, Doherty RA. Methylmercury poisoning in Iraq. Science. 1973;181(4096):230\u201341.","journal-title":"Science"},{"issue":"3","key":"13_CR10","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/j.cbpc.2010.01.001","volume":"151","author":"N Basu","year":"2010","unstructured":"Basu N, Scheuhammer AM, Rouvinen-Watt K, Evans RD, Trudeau VL, Chan LH. In vitro and whole animal evidence that methylmercury disrupts GABAergic systems in discrete brain regions in captive mink. Comp Biochem Physiol C Toxicol Pharmacol. 2010;151(3):379\u201385. doi: 10.1016\/j.cbpc.2010.01.001 .","journal-title":"Comp Biochem Physiol C Toxicol Pharmacol"},{"issue":"5","key":"13_CR11","doi-asserted-by":"publisher","first-page":"703","DOI":"10.1002\/jnr.10419","volume":"70","author":"S Belletti","year":"2002","unstructured":"Belletti S, Orlandini G, Vettori MV, Mutti A, Uggeri J, Scandroglio R, Alinovi R, Gatti R. Time course assessment of methylmercury effects on C6 glioma cells: submicromolar concentrations induce oxidative DNA damage and apoptosis. J Neurosci Res. 2002;70(5):703\u201311. doi: 10.1002\/jnr.10419 .","journal-title":"J Neurosci Res"},{"issue":"2","key":"13_CR12","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.taap.2010.12.005","volume":"251","author":"V Branco","year":"2011","unstructured":"Branco V, Can\u00e1rio J, Holmgren A, Carvalho C. Inhibition of the thioredoxin system in the brain and liver of zebraseabreams exposed to waterborne methylmercury. Toxicol Appl Pharmacol. 2011;251(2):95\u2013103. doi: 10.1016\/j.taap.2010.12.005 .","journal-title":"Toxicol Appl Pharmacol"},{"issue":"4","key":"13_CR13","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1016\/j.freeradbiomed.2011.12.002","volume":"52","author":"V Branco","year":"2012","unstructured":"Branco V, Can\u00e1rio J, Lu J, Holmgren A, Carvalho C. Mercury and selenium interaction in vivo: effects on thioredoxin reductase and glutathione peroxidase. Free Radic Biol Med. 2012;52(4):781\u201393. doi: 10.1016\/j.freeradbiomed.2011.12.002 .","journal-title":"Free Radic Biol Med"},{"key":"13_CR14","doi-asserted-by":"publisher","unstructured":"Bridges K, Venables B, Roberts A. Effects of dietary methylmercury on the dopaminergic system of adult fathead minnows and their offspring. Environ Toxicol Chem. 2016; doi: 10.1002\/etc.3630 .","DOI":"10.1002\/etc.3630"},{"issue":"10\u201311","key":"13_CR15","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1515\/BC.2006.166","volume":"387","author":"R Brigelius-Flohe","year":"2006","unstructured":"Brigelius-Flohe R. Glutathione peroxidases and redox-regulated transcription factors. Biol Chem. 2006;387(10\u201311):1329\u201335. doi: 10.1515\/BC.2006.166 .","journal-title":"Biol Chem"},{"issue":"4","key":"13_CR16","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1111\/j.1471-4159.1989.tb07419.x","volume":"53","author":"N Brookes","year":"1989","unstructured":"Brookes N, Kristt DA. Inhibition of amino acid transport and protein synthesis by HgCl2 and methylmercury in astrocytes: selectivity and reversibility. J Neurochem. 1989;53(4):1228\u201337.","journal-title":"J Neurochem"},{"issue":"3","key":"13_CR17","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/j.tox.2007.07.009","volume":"239","author":"MC Carvalho","year":"2007","unstructured":"Carvalho MC, Franco JL, Ghizoni H, Kobus K, Nazari EM, Rocha JB, Nogueira CW, Dafre AL, Muller YM, Farina M. Effects of 2,3-dimercapto-1-propanesulfonic acid (DMPS) on methylmercury-induced locomotor deficits and cerebellar toxicity in mice. Toxicology. 2007;239(3):195\u2013203. doi: 10.1016\/j.tox.2007.07.009 .","journal-title":"Toxicology"},{"issue":"18","key":"13_CR18","doi-asserted-by":"publisher","first-page":"1279","DOI":"10.1080\/15287390801989036","volume":"71","author":"CM Carvalho","year":"2008","unstructured":"Carvalho CM, Matos AI, Mateus ML, Santos AP, Batoreu MC. High-fish consumption and risk prevention: assessment of exposure to methylmercury in Portugal. J Toxicol Environ Health A. 2008;71(18):1279\u201388. doi: 10.1080\/15287390801989036 .","journal-title":"J Toxicol Environ Health A"},{"issue":"Suppl 1","key":"13_CR19","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1289\/ehp.02110s111","volume":"110","author":"TW Clarkson","year":"2002","unstructured":"Clarkson TW. The three modern faces of mercury. Environ Health Perspect. 2002;110(Suppl 1):11\u201323.","journal-title":"Environ Health Perspect"},{"issue":"18","key":"13_CR20","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1056\/NEJMra022471","volume":"349","author":"TW Clarkson","year":"2003","unstructured":"Clarkson TW, Magos L, Myers GJ. The toxicology of mercury--current exposures and clinical manifestations. N Engl J Med. 2003;349(18):1731\u20137. doi: 10.1056\/NEJMra022471 .","journal-title":"N Engl J Med"},{"issue":"2","key":"13_CR21","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1128\/AEM.50.2.498-502.1985","volume":"50","author":"GC Compeau","year":"1985","unstructured":"Compeau GC, Bartha R. Sulfate-reducing bacteria: principal methylators of mercury in anoxic estuarine sediment. Appl Environ Microbiol. 1985;50(2):498\u2013502.","journal-title":"Appl Environ Microbiol"},{"issue":"5","key":"13_CR22","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1007\/s00210-003-0716-5","volume":"367","author":"E Dare","year":"2003","unstructured":"Dare E, Fetissov S, Hokfelt T, Hall H, Ogren SO, Ceccatelli S. Effects of prenatal exposure to methylmercury on dopamine-mediated locomotor activity and dopamine D2 receptor binding. Naunyn Schmiedeberg\u2019s Arch Pharmacol. 2003;367(5):500\u20138. doi: 10.1007\/s00210-003-0716-5 .","journal-title":"Naunyn Schmiedeberg\u2019s Arch Pharmacol"},{"issue":"1","key":"13_CR23","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3109\/10715769209061085","volume":"17","author":"VM Darley-Usmar","year":"1992","unstructured":"Darley-Usmar VM, Hogg N, O\u2019Leary VJ, Wilson MT, Moncada S. The simultaneous generation of superoxide and nitric oxide can initiate lipid peroxidation in human low density lipoprotein. Free Radic Res Commun. 1992;17(1):9\u201320.","journal-title":"Free Radic Res Commun"},{"issue":"6","key":"13_CR24","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1002\/ana.410350608","volume":"35","author":"LE Davis","year":"1994","unstructured":"Davis LE, Kornfeld M, Mooney HS, Fiedler KJ, Haaland KY, Orrison WW, Cernichiari E, Clarkson TW. Methylmercury poisoning: long-term clinical, radiological, toxicological, and pathological studies of an affected family. Ann Neurol. 1994;35(6):680\u20138. doi: 10.1002\/ana.410350608 .","journal-title":"Ann Neurol"},{"issue":"1","key":"13_CR26","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/j.etap.2004.07.004","volume":"19","author":"MO Dietrich","year":"2005","unstructured":"Dietrich MO, Mantese CE, Anjos GD, Souza DO, Farina M. Motor impairment induced by oral exposure to methylmercury in adult mice. Environ Toxicol Pharmacol. 2005;19(1):169\u201375. doi: 10.1016\/j.etap.2004.07.004 .","journal-title":"Environ Toxicol Pharmacol"},{"key":"13_CR27","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1016\/j.chemosphere.2014.06.045","volume":"139","author":"JG Dorea","year":"2015","unstructured":"Dorea JG. The neurological effects of prenatal and postnatal exposure to mercury need to include ethylmercury. Chemosphere. 2015;139:667\u20138. doi: 10.1016\/j.chemosphere.2014.06.045 .","journal-title":"Chemosphere"},{"issue":"9\u201310","key":"13_CR28","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.1089\/ars.2005.7.1223","volume":"7","author":"R Dringen","year":"2005","unstructured":"Dringen R. Oxidative and antioxidative potential of brain microglial cells. Antioxid Redox Signal. 2005;7(9\u201310):1223\u201333. doi: 10.1089\/ars.2005.7.1223 .","journal-title":"Antioxid Redox Signal"},{"issue":"13","key":"13_CR29","doi-asserted-by":"crossref","first-page":"9746","DOI":"10.1016\/S0021-9258(17)36946-6","volume":"269","author":"WJ Dutczak","year":"1994","unstructured":"Dutczak WJ, Ballatori N. Transport of the glutathione-methylmercury complex across liver canalicular membranes on reduced glutathione carriers. J Biol Chem. 1994;269(13):9746\u201351.","journal-title":"J Biol Chem"},{"issue":"1\u20132","key":"13_CR30","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.jns.2007.06.036","volume":"262","author":"S Ekino","year":"2007","unstructured":"Ekino S, Susa M, Ninomiya T, Imamura K, Kitamura T. Minamata disease revisited: an update on the acute and chronic manifestations of methyl mercury poisoning. J Neurol Sci. 2007;262(1\u20132):131\u201344. doi: 10.1016\/j.jns.2007.06.036 .","journal-title":"J Neurol Sci"},{"issue":"2","key":"13_CR31","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/BF02889124","volume":"23","author":"K Eto","year":"1977","unstructured":"Eto K, Takeuchi T. Pathological changes of human sural nerves in Minamata disease (methylmercury poisoning). Light and electron microscopic studies. Virchows Arch B Cell Pathol. 1977;23(2):109\u201328.","journal-title":"Virchows Arch B Cell Pathol"},{"issue":"1","key":"13_CR33","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1093\/toxsci\/kfg058","volume":"73","author":"M Farina","year":"2003","unstructured":"Farina M, Dahm KC, Schwalm FD, Brusque AM, Frizzo ME, Zeni G, Souza DO, Rocha JB. Methylmercury increases glutamate release from brain synaptosomes and glutamate uptake by cortical slices from suckling rat pups: modulatory effect of ebselen. Toxicol Sci. 2003a;73(1):135\u201340. doi: 10.1093\/toxsci\/kfg058 .","journal-title":"Toxicol Sci"},{"issue":"3","key":"13_CR32","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0378-4274(03)00242-X","volume":"144","author":"M Farina","year":"2003","unstructured":"Farina M, Frizzo ME, Soares FA, Schwalm FD, Dietrich MO, Zeni G, Rocha JB, Souza DO. Ebselen protects against methylmercury-induced inhibition of glutamate uptake by cortical slices from adult mice. Toxicol Lett. 2003b;144(3):351\u20137.","journal-title":"Toxicol Lett"},{"issue":"11","key":"13_CR34","doi-asserted-by":"publisher","first-page":"1503","DOI":"10.1211\/jpp.57.11.0017","volume":"57","author":"M Farina","year":"2005","unstructured":"Farina M, Franco JL, Ribas CM, Meotti FC, Missau FC, Pizzolatti MG, Dafre AL, Santos AR. Protective effects of Polygala paniculata extract against methylmercury-induced neurotoxicity in mice. J Pharm Pharmacol. 2005;57(11):1503\u20138. doi: 10.1211\/jpp.57.11.0017 .","journal-title":"J Pharm Pharmacol"},{"issue":"2","key":"13_CR35","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1093\/toxsci\/kfp219","volume":"112","author":"M Farina","year":"2009","unstructured":"Farina M, Campos F, Vendrell I, Berenguer J, Barzi M, Pons S, Sunol C. Probucol increases glutathione peroxidase-1 activity and displays long-lasting protection against methylmercury toxicity in cerebellar granule cells. Toxicol Sci. 2009;112(2):416\u201326. doi: 10.1093\/toxsci\/kfp219 .","journal-title":"Toxicol Sci"},{"issue":"3","key":"13_CR36","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1016\/j.taap.2011.05.001","volume":"256","author":"M Farina","year":"2011","unstructured":"Farina M, Aschner M, Rocha JB. Oxidative stress in MeHg-induced neurotoxicity. Toxicol Appl Pharmacol. 2011a;256(3):405\u201317. doi: 10.1016\/j.taap.2011.05.001 .","journal-title":"Toxicol Appl Pharmacol"},{"issue":"15\u201316","key":"13_CR37","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1016\/j.lfs.2011.05.019","volume":"89","author":"M Farina","year":"2011","unstructured":"Farina M, Rocha JB, Aschner M. Mechanisms of methylmercury-induced neurotoxicity: evidence from experimental studies. Life Sci. 2011b;89(15\u201316):555\u201363. doi: 10.1016\/j.lfs.2011.05.019 .","journal-title":"Life Sci"},{"key":"13_CR38","doi-asserted-by":"publisher","unstructured":"Feng S, Xu Z, Wang F, Yang T, Liu W, Deng Y, Xu B. Sulforaphane prevents methylmercury-induced oxidative damage and Excitotoxicity through activation of the Nrf2-ARE pathway. Mol Neurobiol. 2016; doi: 10.1007\/s12035-015-9643-y .","DOI":"10.1007\/s12035-015-9643-y"},{"issue":"1","key":"13_CR39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1471-4159.1984.tb09689.x","volume":"42","author":"F Fonnum","year":"1984","unstructured":"Fonnum F. Glutamate: a neurotransmitter in mammalian brain. J Neurochem. 1984;42(1):1\u201311.","journal-title":"J Neurochem"},{"issue":"1","key":"13_CR40","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.envres.2006.02.003","volume":"102","author":"JL Franco","year":"2006","unstructured":"Franco JL, Teixeira A, Meotti FC, Ribas CM, Stringari J, Garcia Pomblum SC, Moro AM, Bohrer D, Bairros AV, Dafre AL, Santos AR, Farina M. Cerebellar thiol status and motor deficit after lactational exposure to methylmercury. Environ Res. 2006;102(1):22\u20138. doi: 10.1016\/j.envres.2006.02.003 .","journal-title":"Environ Res"},{"issue":"12","key":"13_CR41","doi-asserted-by":"publisher","first-page":"1919","DOI":"10.1021\/tx7002323","volume":"20","author":"JL Franco","year":"2007","unstructured":"Franco JL, Braga HC, Stringari J, Missau FC, Posser T, Mendes BG, Leal RB, Santos AR, Dafre AL, Pizzolatti MG, Farina M. Mercurial-induced hydrogen peroxide generation in mouse brain mitochondria: protective effects of quercetin. Chem Res Toxicol. 2007;20(12):1919\u201326. doi: 10.1021\/tx7002323 .","journal-title":"Chem Res Toxicol"},{"issue":"4","key":"13_CR42","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1016\/j.freeradbiomed.2009.05.013","volume":"47","author":"JL Franco","year":"2009","unstructured":"Franco JL, Posser T, Dunkley PR, Dickson PW, Mattos JJ, Martins R, Bainy AC, Marques MR, Dafre AL, Farina M. Methylmercury neurotoxicity is associated with inhibition of the antioxidant enzyme glutathione peroxidase. Free Radic Biol Med. 2009;47(4):449\u201357. doi: 10.1016\/j.freeradbiomed.2009.05.013 .","journal-title":"Free Radic Biol Med"},{"issue":"2","key":"13_CR43","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0006-8993(96)00781-0","volume":"738","author":"AJ Freitas","year":"1996","unstructured":"Freitas AJ, Rocha JB, Wolosker H, Souza DO. Effects of Hg2+ and CH3Hg+ on Ca2+ fluxes in rat brain microsomes. Brain Res. 1996;738(2):257\u201364.","journal-title":"Brain Res"},{"issue":"5","key":"13_CR44","doi-asserted-by":"publisher","first-page":"454","DOI":"10.1016\/j.neuro.2010.05.012","volume":"31","author":"V Glaser","year":"2010","unstructured":"Glaser V, Leipnitz G, Straliotto MR, Oliveira J, dos Santos VV, Wannmacher CM, de Bem AF, Rocha JB, Farina M, Latini A. Oxidative stress-mediated inhibition of brain creatine kinase activity by methylmercury. Neurotoxicology. 2010a;31(5):454\u201360. doi: 10.1016\/j.neuro.2010.05.012 .","journal-title":"Neurotoxicology"},{"issue":"7","key":"13_CR45","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1016\/j.ijdevneu.2010.07.225","volume":"28","author":"V Glaser","year":"2010","unstructured":"Glaser V, Nazari EM, Muller YM, Feksa L, Wannmacher CM, Rocha JB, de Bem AF, Farina M, Latini A. Effects of inorganic selenium administration in methylmercury-induced neurotoxicity in mouse cerebral cortex. Int J Dev Neurosci. 2010b;28(7):631\u20137. doi: 10.1016\/j.ijdevneu.2010.07.225 .","journal-title":"Int J Dev Neurosci"},{"issue":"1\u20132","key":"13_CR46","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11010-013-1870-9","volume":"390","author":"V Glaser","year":"2014","unstructured":"Glaser V, Martins Rde P, Vieira AJ, Oliveira Ede M, Straliotto MR, Mukdsi JH, Torres AI, de Bem AF, Farina M, da Rocha JB, De Paul AL, Latini A. Diphenyl diselenide administration enhances cortical mitochondrial number and activity by increasing hemeoxygenase type 1 content in a methylmercury-induced neurotoxicity mouse model. Mol Cell Biochem. 2014;390(1\u20132):1\u20138. doi: 10.1007\/s11010-013-1870-9 .","journal-title":"Mol Cell Biochem"},{"issue":"3","key":"13_CR001","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1016\/S1474-4422(13)70278-3","volume":"13","author":"P Grandjean","year":"2014","unstructured":"Grandjean P, Landrigan PJ. Neurobehavioural effects of developmental toxicity. Lancet Neurol. 2014;13(3):330\u20138. doi: 10.1016\/S1474-4422(13)70278-3 .","journal-title":"Lancet Neurol"},{"issue":"6","key":"13_CR47","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0892-0362(97)00097-4","volume":"19","author":"P Grandjean","year":"1997","unstructured":"Grandjean P, Weihe P, White RF, Debes F, Araki S, Yokoyama K, Murata K, Sorensen N, Dahl R, Jorgensen PJ. Cognitive deficit in 7-year-old children with prenatal exposure to methylmercury. Neurotoxicol Teratol. 1997;19(6):417\u201328.","journal-title":"Neurotoxicol Teratol"},{"key":"13_CR49","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1039\/BK9781847551771-00365","volume":"7","author":"H Hintelmann","year":"2010","unstructured":"Hintelmann H. Organomercurials. Their formation and pathways in the environment. Met Ions Life Sci. 2010;7:365\u2013401. doi: 10.1039\/BK9781847551771-00365 .","journal-title":"Met Ions Life Sci"},{"issue":"1","key":"13_CR50","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/BF00286572","volume":"57","author":"K Hirayama","year":"1985","unstructured":"Hirayama K, Inouye M, Fujisaki T. Alteration of putative amino acid levels and morphological findings in neural tissues of methylmercury-intoxicated mice. Arch Toxicol. 1985;57(1):35\u201340.","journal-title":"Arch Toxicol"},{"key":"13_CR002","doi-asserted-by":"crossref","unstructured":"Ho T-L. Hard and soft acids and bases principle in organic chemistry. 1st edn. Academic. 1977. eBook ISBN: 9780323140966. Published Date: 28th January 1977.","DOI":"10.1016\/B978-0-12-350050-2.50005-0"},{"key":"13_CR51","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.neuro.2016.04.009","volume":"54","author":"DJ Hoffman","year":"2016","unstructured":"Hoffman DJ, Newland MC. A microstructural analysis distinguishes motor and motivational influences over voluntary running in animals chronically exposed to methylmercury and nimodipine. Neurotoxicology. 2016;54:127\u201339. doi: 10.1016\/j.neuro.2016.04.009 .","journal-title":"Neurotoxicology"},{"issue":"5","key":"13_CR52","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1007\/s002040050279","volume":"70","author":"Y Kajiwara","year":"1996","unstructured":"Kajiwara Y, Yasutake A, Adachi T, Hirayama K. Methylmercury transport across the placenta via neutral amino acid carrier. Arch Toxicol. 1996;70(5):310\u20134.","journal-title":"Arch Toxicol"},{"issue":"2","key":"13_CR53","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1093\/toxsci\/kfm224","volume":"100","author":"P Kaur","year":"2007","unstructured":"Kaur P, Schulz K, Aschner M, Syversen T. Role of docosahexaenoic acid in modulating methylmercury-induced neurotoxicity. Toxicol Sci. 2007;100(2):423\u201332. doi: 10.1093\/toxsci\/kfm224 .","journal-title":"Toxicol Sci"},{"issue":"6","key":"13_CR54","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1016\/j.neuro.2008.06.004","volume":"29","author":"P Kaur","year":"2008","unstructured":"Kaur P, Heggland I, Aschner M, Syversen T. Docosahexaenoic acid may act as a neuroprotector for methylmercury-induced neurotoxicity in primary neural cell cultures. Neurotoxicology. 2008;29(6):978\u201387. doi: 10.1016\/j.neuro.2008.06.004 .","journal-title":"Neurotoxicology"},{"key":"13_CR55","doi-asserted-by":"publisher","first-page":"721987","DOI":"10.1155\/2011\/721987","volume":"2011","author":"P Kaur","year":"2011","unstructured":"Kaur P, Aschner M, Syversen T. Biochemical factors modulating cellular neurotoxicity of methylmercury. J Toxicol. 2011;2011:721987. doi: 10.1155\/2011\/721987 .","journal-title":"J Toxicol"},{"issue":"10","key":"13_CR56","doi-asserted-by":"crossref","first-page":"A304","DOI":"10.1289\/ehp.121-A304","volume":"121","author":"R Kessler","year":"2013","unstructured":"Kessler R. The Minamata convention on mercury: a first step toward protecting future generations. Environ Health Perspect. 2013;121(10):A304\u20139.","journal-title":"Environ Health Perspect"},{"issue":"1","key":"13_CR57","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1203\/01.PDR.0000065736.69214.20","volume":"54","author":"JY Khan","year":"2003","unstructured":"Khan JY, Black SM. Developmental changes in murine brain antioxidant enzymes. Pediatr Res. 2003;54(1):77\u201382. doi: 10.1203\/01.PDR.0000065736.69214.20 .","journal-title":"Pediatr Res"},{"issue":"1\u20133","key":"13_CR58","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0304-4165(01)00236-7","volume":"1569","author":"JY Kim","year":"2002","unstructured":"Kim JY, Park HS, Kang SI, Choi EJ, Kim IY. Redox regulation of cytosolic glycerol-3-phosphate dehydrogenase: Cys(102) is the target of the redox control and essential for the catalytic activity. Biochim Biophys Acta. 2002;1569(1\u20133):67\u201374.","journal-title":"Biochim Biophys Acta"},{"issue":"2","key":"13_CR59","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1002\/jat.2550070208","volume":"7","author":"MP Kung","year":"1987","unstructured":"Kung MP, Kostyniak P, Olson J, Malone M, Roth JA. Studies of the in vitro effect of methylmercury chloride on rat brain neurotransmitter enzymes. J Appl Toxicol. 1987;7(2):119\u201321.","journal-title":"J Appl Toxicol"},{"issue":"6437","key":"13_CR60","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1038\/364535a0","volume":"364","author":"M Lafon-Cazal","year":"1993","unstructured":"Lafon-Cazal M, Pietri S, Culcasi M, Bockaert J. NMDA-dependent superoxide production and neurotoxicity. Nature. 1993;364(6437):535\u20137. doi: 10.1038\/364535a0 .","journal-title":"Nature"},{"issue":"11","key":"13_CR61","doi-asserted-by":"publisher","first-page":"1424","DOI":"10.1016\/j.bbagen.2009.05.014","volume":"1790","author":"AV Lobanov","year":"2009","unstructured":"Lobanov AV, Hatfield DL, Gladyshev VN. Eukaryotic selenoproteins and selenoproteomes. Biochim Biophys Acta. 2009;1790(11):1424\u20138. doi: 10.1016\/j.bbagen.2009.05.014 .","journal-title":"Biochim Biophys Acta"},{"issue":"3","key":"13_CR62","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1046\/j.1471-4159.2001.00589.x","volume":"79","author":"PR Lockman","year":"2001","unstructured":"Lockman PR, Roder KE, Allen DD. Inhibition of the rat blood-brain barrier choline transporter by manganese chloride. J Neurochem. 2001;79(3):588\u201394.","journal-title":"J Neurochem"},{"issue":"2","key":"13_CR63","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1093\/toxsci\/kfl066","volume":"94","author":"RM LoPachin","year":"2006","unstructured":"LoPachin RM, Barber DS. Synaptic cysteine sulfhydryl groups as targets of electrophilic neurotoxicants. Toxicol Sci. 2006;94(2):240\u201355. doi: 10.1093\/toxsci\/kfl066 .","journal-title":"Toxicol Sci"},{"issue":"2","key":"13_CR64","doi-asserted-by":"publisher","first-page":"195","DOI":"10.3109\/10715762.2015.1094184","volume":"50","author":"RM LoPachin","year":"2016","unstructured":"LoPachin RM, Gavin T. Reactions of electrophiles with nucleophilic thiolate sites: relevance to pathophysiological mechanisms and remediation. Free Radic Res. 2016;50(2):195\u2013205. doi: 10.3109\/10715762.2015.1094184 .","journal-title":"Free Radic Res"},{"issue":"2","key":"13_CR65","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1074\/jbc.R800045200","volume":"284","author":"J Lu","year":"2009","unstructured":"Lu J, Holmgren A. Selenoproteins. J Biol Chem. 2009;284(2):723\u20137. doi: 10.1074\/jbc.R800045200 .","journal-title":"J Biol Chem"},{"issue":"22","key":"13_CR66","doi-asserted-by":"crossref","first-page":"6056","DOI":"10.1016\/S0021-9258(18)63505-7","volume":"244","author":"JM McCord","year":"1969","unstructured":"McCord JM, Fridovich I. The utility of superoxide dismutase in studying free radical reactions. I. Radicals generated by the interaction of sulfite, dimethyl sulfoxide, and oxygen. J Biol Chem. 1969;244(22):6056\u201363.","journal-title":"J Biol Chem"},{"issue":"3","key":"13_CR68","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1016\/S0022-3565(25)24557-8","volume":"272","author":"EM Mokrzan","year":"1995","unstructured":"Mokrzan EM, Kerper LE, Ballatori N, Clarkson TW. Methylmercury-thiol uptake into cultured brain capillary endothelial cells on amino acid system L. J Pharmacol Exp Ther. 1995;272(3):1277\u201384.","journal-title":"J Pharmacol Exp Ther"},{"issue":"1\u20133","key":"13_CR69","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/j.tox.2007.05.012","volume":"237","author":"K Mori","year":"2007","unstructured":"Mori K, Yoshida K, Nakagawa Y, Hoshikawa S, Ozaki H, Ito S, Watanabe C. Methylmercury inhibition of type II 5\u2032-deiodinase activity resulting in a decrease in growth hormone production in GH3 cells. Toxicology. 2007;237(1\u20133):203\u20139. doi: 10.1016\/j.tox.2007.05.012 .","journal-title":"Toxicology"},{"issue":"2","key":"13_CR70","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/j.jpeds.2003.10.059","volume":"144","author":"K Murata","year":"2004","unstructured":"Murata K, Weihe P, Budtz-Jorgensen E, Jorgensen PJ, Grandjean P. Delayed brainstem auditory evoked potential latencies in 14-year-old children exposed to methylmercury. J Pediatr. 2004;144(2):177\u201383. doi: 10.1016\/j.jpeds.2003.10.059 .","journal-title":"J Pediatr"},{"issue":"5","key":"13_CR71","doi-asserted-by":"publisher","first-page":"810","DOI":"10.1002\/glia.21153","volume":"59","author":"M Ni","year":"2011","unstructured":"Ni M, Li X, Yin Z, Sidoryk-Wegrzynowicz M, Jiang H, Farina M, Rocha JB, Syversen T, Aschner M. Comparative study on the response of rat primary astrocytes and microglia to methylmercury toxicity. Glia. 2011;59(5):810\u201320. doi: 10.1002\/glia.21153 .","journal-title":"Glia"},{"issue":"4","key":"13_CR72","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1016\/j.ntt.2005.03.008","volume":"27","author":"T Ninomiya","year":"2005","unstructured":"Ninomiya T, Imamura K, Kuwahata M, Kindaichi M, Susa M, Ekino S. Reappraisal of somatosensory disorders in methylmercury poisoning. Neurotoxicol Teratol. 2005;27(4):643\u201353. doi: 10.1016\/j.ntt.2005.03.008 .","journal-title":"Neurotoxicol Teratol"},{"issue":"2","key":"13_CR73","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0165-3806(85)90219-6","volume":"353","author":"JR O\u2019Kusky","year":"1985","unstructured":"O\u2019Kusky JR, McGeer EG. Methylmercury poisoning of the developing nervous system in the rat: decreased activity of glutamic acid decarboxylase in cerebral cortex and neostriatum. Brain Res. 1985;353(2):299\u2013306.","journal-title":"Brain Res"},{"issue":"13","key":"13_CR74","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1016\/0006-2952(74)90199-3","volume":"23","author":"M Osawa","year":"1974","unstructured":"Osawa M, Magos L. The chemical form of the methylmercury complex in the bile of the rat. Biochem Pharmacol. 1974;23(13):1903\u20135.","journal-title":"Biochem Pharmacol"},{"key":"13_CR75","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.freeradbiomed.2014.07.019","volume":"75","author":"S Penglase","year":"2014","unstructured":"Penglase S, Hamre K, Ellingsen S. Selenium prevents downregulation of antioxidant selenoprotein genes by methylmercury. Free Radic Biol Med. 2014;75:95\u2013104. doi: 10.1016\/j.freeradbiomed.2014.07.019 .","journal-title":"Free Radic Biol Med"},{"issue":"3-4","key":"13_CR003","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/S0891-5849(00)00313-0","volume":"29","author":"G Powis","year":"2000","unstructured":"Powis G, Mustacich D, Coon A. The role of the redox protein thioredoxin in cell growth and cancer. Free Radic Biol Med. 2000;29(3-4):312\u201322.","journal-title":"Free Radic Biol Med"},{"issue":"2","key":"13_CR77","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0006-3061(00)80237-9","volume":"8","author":"DL Rabenstein","year":"1978","unstructured":"Rabenstein DL, Evans CA. The mobility of methylmercury in biological systems. Bioinorg Chem. 1978;8(2):107\u2013101,104.","journal-title":"Bioinorg Chem"},{"issue":"2","key":"13_CR78","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/0003-9861(91)90224-7","volume":"288","author":"R Radi","year":"1991","unstructured":"Radi R, Beckman JS, Bush KM, Freeman BA. Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. Arch Biochem Biophys. 1991;288(2):481\u20137.","journal-title":"Arch Biochem Biophys"},{"issue":"4","key":"13_CR79","first-page":"214","volume":"5","author":"T Rahola","year":"1973","unstructured":"Rahola T, Hattula T, Korolainen A, Miettinen JK. Elimination of free and protein-bound ionic mercury (20Hg2+) in man. Ann Clin Res. 1973;5(4):214\u20139.","journal-title":"Ann Clin Res"},{"issue":"5","key":"13_CR80","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1139\/y87-127","volume":"65","author":"JN Reynolds","year":"1987","unstructured":"Reynolds JN, Racz WJ. Effects of methylmercury on the spontaneous and potassium-evoked release of endogenous amino acids from mouse cerebellar slices. Can J Physiol Pharmacol. 1987;65(5):791\u20138.","journal-title":"Can J Physiol Pharmacol"},{"issue":"3","key":"13_CR81","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/0041-008X(75)90274-4","volume":"31","author":"RJ Richardson","year":"1975","unstructured":"Richardson RJ, Murphy SD. Effect of glutathione depletion on tissue deposition of methylmercury in rats. Toxicol Appl Pharmacol. 1975;31(3):505\u201319.","journal-title":"Toxicol Appl Pharmacol"},{"issue":"3","key":"13_CR82","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1016\/j.jchemneu.2008.01.003","volume":"35","author":"E Roda","year":"2008","unstructured":"Roda E, Coccini T, Acerbi D, Castoldi A, Bernocchi G, Manzo L. Cerebellum cholinergic muscarinic receptor (subtype-2 and -3) and cytoarchitecture after developmental exposure to methylmercury: an immunohistochemical study in rat. J Chem Neuroanat. 2008;35(3):285\u201394. doi: 10.1016\/j.jchemneu.2008.01.003 .","journal-title":"J Chem Neuroanat"},{"issue":"1","key":"13_CR85","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1016\/j.taap.2011.01.010","volume":"252","author":"DH Roos","year":"2011","unstructured":"Roos DH, Puntel RL, Farina M, Aschner M, Bohrer D, Rocha JB, de Vargas Barbosa NB. Modulation of methylmercury uptake by methionine: prevention of mitochondrial dysfunction in rat liver slices by a mimicry mechanism. Toxicol Appl Pharmacol. 2011;252(1):28\u201335. doi: 10.1016\/j.taap.2011.01.010 .","journal-title":"Toxicol Appl Pharmacol"},{"issue":"5","key":"13_CR86","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/0891-5849(89)90034-8","volume":"7","author":"ER Rosenblum","year":"1989","unstructured":"Rosenblum ER, Gavaler JS, Van Thiel DH. Lipid peroxidation: a mechanism for alcohol-induced testicular injury. Free Radic Biol Med. 1989;7(5):569\u201377.","journal-title":"Free Radic Biol Med"},{"issue":"3","key":"13_CR87","doi-asserted-by":"publisher","first-page":"476","DOI":"10.1016\/j.neuro.2012.03.004","volume":"33","author":"T Rush","year":"2012","unstructured":"Rush T, Liu X, Nowakowski AB, Petering DH, Lobner D. Glutathione-mediated neuroprotection against methylmercury neurotoxicity in cortical culture is dependent on MRP1. Neurotoxicology. 2012;33(3):476\u201381. doi: 10.1016\/j.neuro.2012.03.004 .","journal-title":"Neurotoxicology"},{"issue":"3","key":"13_CR88","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1600-0773.1996.tb00203.x","volume":"78","author":"M Sakamoto","year":"1996","unstructured":"Sakamoto M, Ikegami N, Nakano A. Protective effects of Ca2+ channel blockers against methyl mercury toxicity. Pharmacol Toxicol. 1996;78(3):193\u20139.","journal-title":"Pharmacol Toxicol"},{"issue":"5","key":"13_CR89","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.4049\/jimmunol.156.5.1973","volume":"156","author":"T Seres","year":"1996","unstructured":"Seres T, Ravichandran V, Moriguchi T, Rokutan K, Thomas JA, Johnston RB Jr. Protein S-thiolation and dethiolation during the respiratory burst in human monocytes. A reversible post-translational modification with potential for buffering the effects of oxidant stress. J Immunol. 1996;156(5):1973\u201380.","journal-title":"J Immunol"},{"issue":"1\u20132","key":"13_CR90","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.molbrainres.2005.02.006","volume":"137","author":"G Shanker","year":"2005","unstructured":"Shanker G, Syversen T, Aschner JL, Aschner M. Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes. Brain Res Mol Brain Res. 2005;137(1\u20132):11\u201322. doi: 10.1016\/j.molbrainres.2005.02.006 .","journal-title":"Brain Res Mol Brain Res"},{"key":"13_CR91","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.bbr.2016.07.049","volume":"315","author":"AN Shen","year":"2016","unstructured":"Shen AN, Cummings C, Hoffman D, Pope D, Arnold M, Newland MC. Aging, motor function, and sensitivity to calcium channel blockers: an investigation using chronic methylmercury exposure. Behav Brain Res. 2016;315:103\u201314. doi: 10.1016\/j.bbr.2016.07.049 .","journal-title":"Behav Brain Res"},{"issue":"12","key":"13_CR92","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1023\/A:1026175825871","volume":"28","author":"FA Soares","year":"2003","unstructured":"Soares FA, Farina M, Santos FW, Souza D, Rocha JB, Nogueira CW. Interaction between metals and chelating agents affects glutamate binding on brain synaptic membranes. Neurochem Res. 2003;28(12):1859\u201365.","journal-title":"Neurochem Res"},{"issue":"1","key":"13_CR93","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.taap.2007.10.010","volume":"227","author":"J Stringari","year":"2008","unstructured":"Stringari J, Nunes AK, Franco JL, Bohrer D, Garcia SC, Dafre AL, Milatovic D, Souza DO, Rocha JB, Aschner M, Farina M. Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain. Toxicol Appl Pharmacol. 2008;227(1):147\u201354. doi: 10.1016\/j.taap.2007.10.010 .","journal-title":"Toxicol Appl Pharmacol"},{"issue":"1","key":"13_CR94","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/BF02307267","volume":"66","author":"I Suda","year":"1992","unstructured":"Suda I, Takahashi H. Degradation of methyl and ethyl mercury into inorganic mercury by other reactive oxygen species besides hydroxyl radical. Arch Toxicol. 1992;66(1):34\u20139.","journal-title":"Arch Toxicol"},{"issue":"2","key":"13_CR95","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1093\/toxsci\/kfr134","volume":"122","author":"PT Theunissen","year":"2011","unstructured":"Theunissen PT, Pennings JL, Robinson JF, Claessen SM, Kleinjans JC, Piersma AH. Time-response evaluation by transcriptomics of methylmercury effects on neural differentiation of murine embryonic stem cells. Toxicol Sci. 2011;122(2):437\u201347. doi: 10.1093\/toxsci\/kfr134 .","journal-title":"Toxicol Sci"},{"issue":"4","key":"13_CR96","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1007\/s00204-015-1528-3","volume":"90","author":"F Usuki","year":"2016","unstructured":"Usuki F, Fujimura M. Decreased plasma thiol antioxidant barrier and selenoproteins as potential biomarkers for ongoing methylmercury intoxication and an individual protective capacity. Arch Toxicol. 2016;90(4):917\u201326. doi: 10.1007\/s00204-015-1528-3 .","journal-title":"Arch Toxicol"},{"issue":"8","key":"13_CR97","doi-asserted-by":"publisher","first-page":"6641","DOI":"10.1074\/jbc.M110.168872","volume":"286","author":"F Usuki","year":"2011","unstructured":"Usuki F, Yamashita A, Fujimura M. Post-transcriptional defects of antioxidant selenoenzymes cause oxidative stress under methylmercury exposure. J Biol Chem. 2011;286(8):6641\u20139. doi: 10.1074\/jbc.M110.168872 .","journal-title":"J Biol Chem"},{"issue":"2","key":"13_CR98","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/0041-008X(80)90428-7","volume":"53","author":"R Burg Von","year":"1980","unstructured":"Von Burg R, Northington FK, Shamoo A. Methylmercury inhibition of rat brain muscarinic receptors. Toxicol Appl Pharmacol. 1980;53(2):285\u201392.","journal-title":"Toxicol Appl Pharmacol"},{"issue":"6","key":"13_CR99","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1007\/s10534-010-9367-4","volume":"23","author":"C Wagner","year":"2010","unstructured":"Wagner C, Sudati JH, Nogueira CW, Rocha JB. In vivo and in vitro inhibition of mice thioredoxin reductase by methylmercury. Biometals. 2010;23(6):1171\u20137. doi: 10.1007\/s10534-010-9367-4 .","journal-title":"Biometals"},{"issue":"1","key":"13_CR101","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0892-0362(98)00036-1","volume":"21","author":"C Watanabe","year":"1999","unstructured":"Watanabe C, Yin K, Kasanuma Y, Satoh H. In utero exposure to methylmercury and se deficiency converge on the neurobehavioral outcome in mice. Neurotoxicol Teratol. 1999;21(1):83\u20138.","journal-title":"Neurotoxicol Teratol"},{"issue":"4","key":"13_CR102","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/j.neuro.2011.12.004","volume":"33","author":"U Wormser","year":"2012","unstructured":"Wormser U, Brodsky B, Milatovic D, Finkelstein Y, Farina M, Rocha JB, Aschner M. Protective effect of a novel peptide against methylmercury-induced toxicity in rat primary astrocytes. Neurotoxicology. 2012;33(4):763\u20138. doi: 10.1016\/j.neuro.2011.12.004 .","journal-title":"Neurotoxicology"},{"issue":"1","key":"13_CR103","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.brainres.2006.10.070","volume":"1131","author":"Z Yin","year":"2007","unstructured":"Yin Z, Milatovic D, Aschner JL, Syversen T, Rocha JB, Souza DO, Sidoryk M, Albrecht J, Aschner M. Methylmercury induces oxidative injury, alterations in permeability and glutamine transport in cultured astrocytes. Brain Res. 2007;1131(1):1\u201310. doi: 10.1016\/j.brainres.2006.10.070 .","journal-title":"Brain Res"},{"issue":"4","key":"13_CR104","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1111\/j.1471-4159.2008.05683.x","volume":"107","author":"Z Yin","year":"2008","unstructured":"Yin Z, Jiang H, Syversen T, Rocha JB, Farina M, Aschner M. The methylmercury-L-cysteine conjugate is a substrate for the L-type large neutral amino acid transporter. J Neurochem. 2008;107(4):1083\u201390. doi: 10.1111\/j.1471-4159.2008.05683.x .","journal-title":"J Neurochem"},{"issue":"1","key":"13_CR106","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.tox.2012.07.013","volume":"302","author":"AP Zemolin","year":"2012","unstructured":"Zemolin AP, Meinerz DF, de Paula MT, Mariano DO, Rocha JB, Pereira AB, Posser T, Franco JL. Evidences for a role of glutathione peroxidase 4 (GPx4) in methylmercury induced neurotoxicity in vivo. Toxicology. 2012;302(1):60\u20137. doi: 10.1016\/j.tox.2012.07.013 .","journal-title":"Toxicology"},{"issue":"2","key":"13_CR107","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1093\/toxsci\/kfr054","volume":"121","author":"B Zimmer","year":"2011","unstructured":"Zimmer B, Schildknecht S, Kuegler PB, Tanavde V, Kadereit S, Leist M. Sensitivity of dopaminergic neuron differentiation from stem cells to chronic low-dose methylmercury exposure. Toxicol Sci. 2011;121(2):357\u201367. doi: 10.1093\/toxsci\/kfr054 .","journal-title":"Toxicol Sci"}],"container-title":["Advances in Neurobiology","Neurotoxicity of Metals"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-319-60189-2_13","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T17:38:18Z","timestamp":1750873098000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-319-60189-2_13"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"ISBN":["9783319601885","9783319601892"],"references-count":102,"URL":"https:\/\/doi.org\/10.1007\/978-3-319-60189-2_13","relation":{},"ISSN":["2190-5215","2190-5223"],"issn-type":[{"value":"2190-5215","type":"print"},{"value":"2190-5223","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}