{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T01:51:27Z","timestamp":1743126687019,"version":"3.40.3"},"publisher-location":"Berlin, Heidelberg","reference-count":3,"publisher":"Springer Berlin Heidelberg","isbn-type":[{"type":"print","value":"9783540223436"},{"type":"electronic","value":"9783540248552"}],"license":[{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004]]},"DOI":"10.1007\/978-3-540-24855-2_36","type":"book-chapter","created":{"date-parts":[[2010,9,14]],"date-time":"2010-09-14T08:20:59Z","timestamp":1284452459000},"page":"385-386","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Molecular Binding Energy Analysis of HIV-1 Protease Inhibitors Using Genetic Algorithm-Based Partial Least Squares Method"],"prefix":"10.1007","author":[{"given":"Yen-Chih","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinn-Moon","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi-Hung","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng-Yan","family":"Kao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"36_CR1","doi-asserted-by":"publisher","first-page":"2681","DOI":"10.1021\/jm00014a020","volume":"38","author":"A.R. Ortiz","year":"1995","unstructured":"Ortiz, A.R., Pisabarro, M.T., Gago, F., Wade, R.C.: Prediction of Drug Binding Affinities by Comparative Binding Energy Analysis. J. Med. Chem.\u00a038, 2681\u20132691 (1995)","journal-title":"J. Med. Chem."},{"key":"36_CR2","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1002\/(SICI)1521-3838(199907)18:3<262::AID-QSAR262>3.0.CO;2-S","volume":"18","author":"K. Hasegawa","year":"1999","unstructured":"Hasegawa, K., Kimura, T., Funatsu, K.: GA Strategy for Variable Selection in QSAR Studies: Enhancement of Comparative Molecular Binding Energy Analysis by GA-Based PLS Method. Quant. Struct.-Act. Relat.\u00a018, 262\u2013272 (1999)","journal-title":"Quant. Struct.-Act. Relat."},{"key":"36_CR3","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1021\/jm970535b","volume":"41","author":"C. Perez","year":"1998","unstructured":"Perez, C., Pastor, M., Ortiz, A.R., Gago, F.: Comparative Binding Energy Analysis of HIV- 1 Protease Inhibitors: Incorporation of Solvent Effects and Validation as a Powerful Tool in Receptor-Based Drug Design. J. Med. Chem.\u00a041, 836\u2013852 (1998)","journal-title":"J. Med. Chem."}],"container-title":["Lecture Notes in Computer Science","Genetic and Evolutionary Computation \u2013 GECCO 2004"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-540-24855-2_36","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,8]],"date-time":"2023-02-08T23:50:12Z","timestamp":1675900212000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-540-24855-2_36"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004]]},"ISBN":["9783540223436","9783540248552"],"references-count":3,"URL":"https:\/\/doi.org\/10.1007\/978-3-540-24855-2_36","relation":{},"ISSN":["0302-9743","1611-3349"],"issn-type":[{"type":"print","value":"0302-9743"},{"type":"electronic","value":"1611-3349"}],"subject":[],"published":{"date-parts":[[2004]]}}}