{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T19:13:08Z","timestamp":1771009988560,"version":"3.50.1"},"publisher-location":"Berlin, Heidelberg","reference-count":62,"publisher":"Springer Berlin Heidelberg","isbn-type":[{"value":"9783540225669","type":"print"},{"value":"9783540278627","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004]]},"DOI":"10.1007\/978-3-540-27862-7_2","type":"book-chapter","created":{"date-parts":[[2010,9,7]],"date-time":"2010-09-07T03:26:24Z","timestamp":1283829984000},"page":"24-54","source":"Crossref","is-referenced-by-count":20,"title":["On\u00a0the\u00a0Nested\u00a0Hierarchical\u00a0Organization\u00a0of\u00a0CNS: Basic Characteristics of Neuronal Molecular Networks"],"prefix":"10.1007","author":[{"given":"Luigi Francesco","family":"Agnati","sequence":"first","affiliation":[]},{"given":"Letizia","family":"Santarossa","sequence":"additional","affiliation":[]},{"given":"Susanna","family":"Genedani","sequence":"additional","affiliation":[]},{"given":"Enric I.","family":"Canela","sequence":"additional","affiliation":[]},{"given":"Giuseppina","family":"Leo","sequence":"additional","affiliation":[]},{"given":"Rafael","family":"Franco","sequence":"additional","affiliation":[]},{"given":"Amina","family":"Woods","sequence":"additional","affiliation":[]},{"given":"Carmen","family":"Lluis","sequence":"additional","affiliation":[]},{"given":"Sergi","family":"Ferr\u00e9","sequence":"additional","affiliation":[]},{"given":"Kjell","family":"Fuxe","sequence":"additional","affiliation":[]}],"member":"297","reference":[{"key":"2_CR1","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1038\/nature01254","volume":"420","author":"H. Kitano","year":"2002","unstructured":"Kitano, H.: Computational Systems Biology. Nature\u00a0420, 206\u2013210 (2002)","journal-title":"Nature"},{"key":"2_CR2","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1093\/oxfordjournals.molbev.a003957","volume":"18","author":"S. Wuchy","year":"2001","unstructured":"Wuchy, S.: Scale-free behaviour in Protein Domain Networks. Mol. Biol. Evol.\u00a018, 1694\u20131702 (2001)","journal-title":"Mol. Biol. Evol."},{"key":"2_CR3","first-page":"599","volume":"299","author":"A.L. Barbasi","year":"2001","unstructured":"Barbasi, A.L., Ravasz, E., Vicsek, T.: Deterministic scale-free networks. Phys. Acta\u00a0299, 599\u2013604 (2001)","journal-title":"Phys. Acta"},{"key":"2_CR4","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1126\/science.286.5439.509","volume":"286","author":"A.L. Barbasi","year":"1999","unstructured":"Barbasi, A.L., Albert, R.: Emergence of Scaling Networks. Science\u00a0286, 509\u2013512 (1999)","journal-title":"Science"},{"key":"2_CR5","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1038\/30918","volume":"393","author":"D.J. Watts","year":"1998","unstructured":"Watts, D.J., Strogatz, S.H.: Collective dynamics of \u201csmall\u2013world\u201d networks. Nature\u00a0393, 440\u2013442 (1998)","journal-title":"Nature"},{"key":"2_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s00294-002-0285-z","volume":"41","author":"H. Kitano","year":"2002","unstructured":"Kitano, H.: Looking beyond the details: a rise in system-oriented approaches in genetics and molecular biology. Curr. Genet.\u00a041, 1\u201310 (2002)","journal-title":"Curr. Genet."},{"key":"2_CR7","first-page":"58","volume-title":"New Research Strategies in Biological Psychiatry","author":"L.F. Agnati","year":"1984","unstructured":"Agnati, L.F., Fuxe, K., Battistini, N., Zini, I., Benfenati, F., Merlo Pich, E., Farabegoli, C., Zoli, M., Andersson, K., Harfstrand, A.: Multiple transmission lines in central synapses and their interactions. In: Kemali, D., et al. (eds.) New Research Strategies in Biological Psychiatry, pp. 58\u201371. John Libbey, London (1984)"},{"key":"2_CR8","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/0197-0186(90)90008-H","volume":"16","author":"L.F. Agnati","year":"1990","unstructured":"Agnati, L.F., Zoli, M., Merlo Pich, E., Benfenati, F., Fuxe, K.: Aspects of neural plasticity in the central nervous system. VII. Theoretical aspects of brain communication and computation. Neurochem. Int.\u00a016, 479\u2013500 (1990)","journal-title":"Neurochem. Int."},{"key":"2_CR9","doi-asserted-by":"publisher","first-page":"2538","DOI":"10.1073\/pnas.012582499","volume":"99","author":"J.M. Carlson","year":"2002","unstructured":"Carlson, J.M., Doyle, J.: Complexity and robustness. Proc. Natl. Acad. Sci. USA\u00a099, 2538\u20132545 (2002)","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2_CR10","doi-asserted-by":"publisher","first-page":"1664","DOI":"10.1126\/science.1069981","volume":"295","author":"M.E. Csete","year":"2002","unstructured":"Csete, M.E., Doyle, J.C.: Reverse Engineering of Biological Complexity. Science\u00a0295, 1664\u20131669 (2002)","journal-title":"Science"},{"key":"2_CR11","doi-asserted-by":"crossref","unstructured":"Bacon, F.: Instauratio Magna. In: Collier, P.F. & Son (eds.) Famous Prefaces, vol.\u00a039, The Harvard Classics, New York (1909-1914)","DOI":"10.1017\/CBO9781139149549.006"},{"key":"2_CR12","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1007\/BF01120304","volume":"4","author":"L.F. Agnati","year":"1984","unstructured":"Agnati, L.F., Fuxe, K.: New concepts on the structure of the neuronal networks: the miniaturization and hierarchical organization of the central nervous system. Biosci. Rep.\u00a04, 93\u201398 (1984)","journal-title":"Biosci. Rep."},{"key":"2_CR13","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/S0079-6123(00)25003-6","volume":"125","author":"L.F. Agnati","year":"2000","unstructured":"Agnati, L.F., Fuxe, K.: Volume transmission as a key feature of information handling in the central nervous system possible new interpretative value of the Turing\u2019s B-type machine. Progr. Brain Res.\u00a0125, 3\u201319 (2000)","journal-title":"Progr. Brain Res."},{"key":"2_CR14","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/0006-8993(95)00026-M","volume":"676","author":"L.F. Agnati","year":"1995","unstructured":"Agnati, L.F., Tinner, B., Staines, W.A., V\u00e4\u00e4n\u00e4en, K., Fuxe, K.: On the cellular localization and distribution of carbonic anhydrase II immunoreactivity in the rat brain. Brain Res.\u00a0676, 10\u201324 (1995)","journal-title":"Brain Res."},{"key":"2_CR15","first-page":"299","volume":"13","author":"P. Goldman-Rakic","year":"1975","unstructured":"Goldman-Rakic, P.: Local Circuit Neurons. Neurosci. Res. Prog. Bull.\u00a013, 299\u2013313 (1975)","journal-title":"Neurosci. Res. Prog. Bull."},{"key":"2_CR16","first-page":"224","volume":"59","author":"L.F. Agnati","year":"1981","unstructured":"Agnati, L.F., Fuxe, K., Ferri, M., Benfenati, F., \u00d6gren, S.O.: A new hypothesis on memory. A possible role of local circuits in the formation of the memory trace. Med. Biol.\u00a059, 224\u2013229 (1981)","journal-title":"Med. Biol."},{"key":"2_CR17","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1124\/pr.55.3.2","volume":"55","author":"L.F. Agnati","year":"2003","unstructured":"Agnati, L.F., Ferr\u00e9, S., Lluis, C., Franco, R., Fuxe, K.: Molecular Mechanisms and Therapeutical Implications of Intramembrane Receptor \/ Receptor Interactions among Heptahelical Receptors with Examples from the Striopallidal GABA neurons. Pharmacol. Rev.\u00a055, 509\u2013550 (2003)","journal-title":"Pharmacol. Rev."},{"key":"2_CR18","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1126\/science.180598","volume":"193","author":"F.O. Schmitt","year":"1976","unstructured":"Schmitt, F.O., Dev, P., Smith, B.H.: Electrotonic processing of information by brain cells. Science\u00a0193, 114\u2013120 (1976)","journal-title":"Science"},{"key":"2_CR19","first-page":"1","volume-title":"Systems Neuroscience","author":"J. Metzler","year":"1977","unstructured":"Metzler, J.: Mental Transformations: A top-Down Analysis. In: Metzler, J. (ed.) Systems Neuroscience, pp. 1\u201324. Academic Press, New York (1977)"},{"key":"2_CR20","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1146\/annurev.ne.08.030185.002101","volume":"8","author":"M.M. Poo","year":"1985","unstructured":"Poo, M.M.: Mobility and localization of proteins in excitable membranes. Annu. Rev. Neurosci.\u00a08, 369\u2013406 (1985)","journal-title":"Annu. Rev. Neurosci."},{"key":"2_CR21","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/978-1-4615-0705-5_9","volume-title":"From Synapses to Rules","author":"L.F. Agnati","year":"2002","unstructured":"Agnati, L.F., Santarossa, L.M., Benfenati, F., Ferri, M., Morpurgo, A., Apolloni, B., Fuxe, K.: Molecular basis of learning and memory: modelling based on receptor mosaics. In: Apolloni, B., Kurfess, F. (eds.) From Synapses to Rules, pp. 165\u2013196. Kluwer Academic\/Plenum Publishers, New York (2002)"},{"key":"2_CR22","doi-asserted-by":"publisher","first-page":"5031","DOI":"10.1073\/pnas.97.10.5031","volume":"97","author":"D.A. Lauffenburger","year":"2000","unstructured":"Lauffenburger, D.A.: Cell signalling pathways as control modules: Complexity for simplicity? Proc. Natl. Acad. Sci. USA\u00a097, 5031\u20135033 (2000)","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2_CR23","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1016\/S0165-6147(03)00232-3","volume":"24","author":"C. Bergson","year":"2003","unstructured":"Bergson, C., Levenson, R., Goldman-Rakic, P.S., Lidow, M.S.: Dopamine-receptorinteracting proteins: the Ca2+ connection in dopamine signaling. Trends Pharmacol. Sci.\u00a024, 486\u2013492 (2003)","journal-title":"Trends Pharmacol. Sci."},{"key":"2_CR24","volume-title":"Biochemistry and Molecular Biology","year":"2002","unstructured":"Elliott, W.H., Elliott, D.C. (eds.): Biochemistry and Molecular Biology. Oxford University Press, Oxford (2002)"},{"key":"2_CR25","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1111\/j.1748-1716.1986.tb07967.x","volume":"128","author":"L.F. Agnati","year":"1986","unstructured":"Agnati, L.F., Fuxe, K., Zoli, M., Zini, I., Toffano, G., Ferraguti, F.: A correlation analysis of the regional distribution of central enkephalin and endorphin immunoreactive terminals and of opiate receptors in adult and old male rats. Acta Physiol. Scand.\u00a0128, 201\u2013207 (1986)","journal-title":"Acta Physiol. Scand."},{"key":"2_CR26","series-title":"Advances in Neuroscience","first-page":"1","volume-title":"Volume Transmission in the Brain. Novel Mechanisms for Neural Transmission","author":"K. Fuxe","year":"1991","unstructured":"Fuxe, K., Agnati, L.F.: Two principal modes of electrochemical communication in the brain: volume versus wiring transmission. In: Fuxe, K., Agnati, L.F. (eds.) Volume Transmission in the Brain. Novel Mechanisms for Neural Transmission. Advances in Neuroscience, vol.\u00a01, pp. 1\u20139. Raven Press, New York (1991)"},{"key":"2_CR27","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/S0968-0004(01)02003-5","volume":"27","author":"A.S. Verkman","year":"2002","unstructured":"Verkman, A.S.: Solute and macromolecule diffusion in cellular aqueous compartment. Trends Biol. Sci.\u00a027, 27\u201333 (2002)","journal-title":"Trends Biol. Sci."},{"key":"2_CR28","volume-title":"Protein Structure and Function","author":"G.A. Petsko","year":"2004","unstructured":"Petsko, G.A., Ringe, D.: Protein Structure and Function. Sinauer Associates, Inc. Publisher, Sunderland (2004)"},{"key":"2_CR29","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1126\/science.284.5411.92","volume":"284","author":"G. Weng","year":"1999","unstructured":"Weng, G., Bhalla, U.S., Iyengar, R.: Complexity in Biological Signalling Systems. Science\u00a0284, 92\u201396 (1999)","journal-title":"Science"},{"key":"2_CR30","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1126\/science.1076979","volume":"299","author":"S.H. Park","year":"2003","unstructured":"Park, S.H., Zarrinpar, A., Lim, W.A.: Rewiring MAP Kinase Pathways Using Alternative Scaffold Assembly Mechanisms. Science\u00a0299, 1061\u20131064 (2003)","journal-title":"Science"},{"key":"2_CR31","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1038\/373573a0","volume":"373","author":"T. Pawson","year":"1995","unstructured":"Pawson, T.: Protein modules and signalling networks. Nature\u00a0373, 573\u2013580 (1995)","journal-title":"Nature"},{"key":"2_CR32","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1038\/35094577","volume":"2","author":"K.L. Pierce","year":"2001","unstructured":"Pierce, K.L., Lefkowitz, R.J.: Classical and new roles of beta-arrestins in the regulation of G-protein-coupled receptors. Nat. Rev. Neurosci.\u00a02, 727\u2013733 (2001)","journal-title":"Nat. Rev. Neurosci."},{"key":"2_CR33","first-page":"195","volume":"65","author":"L.F. Agnati","year":"2003","unstructured":"Agnati, L.F., Franzen, O., Ferr\u00e9, S., Leo, G., Franco, R., Fuxe, K.: Possibile role of intramembrane receptor-receptor interactions in memory and learning via formation of long-lived heteromeric complexes: focus on motor learning in the basal ganglia. J. Neural. Transm.\u00a065, 195\u2013222 (2003)","journal-title":"J. Neural. Transm."},{"key":"2_CR34","first-page":"2075","volume":"278","author":"T. Pawson","year":"1997","unstructured":"Pawson, T., Scott, J.D.: Signaling Through Scaffold, Anchoring, and Adaptor. Proteins Science\u00a0278, 2075\u20132080 (1997)","journal-title":"Proteins Science"},{"key":"2_CR35","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1016\/S0962-8924(01)02154-7","volume":"11","author":"T. Pawson","year":"2001","unstructured":"Pawson, T., Gish, G.D., Nash, P.: SH2 domains, interaction modules and cellular wiring Trend Cell Biol. Trend Cell Biol.\u00a011, 504\u2013511 (2001)","journal-title":"Trend Cell Biol."},{"key":"2_CR36","doi-asserted-by":"crossref","first-page":"E133","DOI":"10.1038\/35017152","volume":"2","author":"R.J. Lefkowitz","year":"2000","unstructured":"Lefkowitz, R.J.: The superfamily of heptahelical receptors. Nat. Cell Biol.\u00a02, E133\u2013E136 (2000)","journal-title":"Nat. Cell Biol"},{"key":"2_CR37","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/S0165-0173(97)00057-X","volume":"26","author":"P. Greengard","year":"1998","unstructured":"Greengard, P., Nairn, A.C., Girault, J.A., Ouimet, C.C., Snyder, G.L., Fisone, G., Allen, P.B., Fienberg, A., Nishi, A.: The DARPP-32\/protein phosphatase-1 cascade: a model for signal integration. Brain Res. Rew.\u00a026, 274\u2013284 (1998)","journal-title":"Brain Res. Rew."},{"key":"2_CR38","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/S0092-8674(00)81688-8","volume":"100","author":"T. Hunter","year":"2000","unstructured":"Hunter, T.: Signalling - 2000 and beyond. Cell\u00a0100, 113\u2013127 (2000)","journal-title":"Cell"},{"key":"2_CR39","first-page":"182","volume":"58","author":"L.F. Agnati","year":"1980","unstructured":"Agnati, L.F., Fuxe, K., Zini, I., Lenzi, P., H\u00f6kfelt, T.: Aspects on receptor regulation and isoreceptor identification. Med. Biol.\u00a058, 182\u2013187 (1980)","journal-title":"Med. Biol."},{"key":"2_CR40","series-title":"A New Intramembrane Integrative Mechanism","first-page":"14","volume-title":"Receptor-Receptor Interactions","author":"K. Fuxe","year":"1987","unstructured":"Fuxe, K., Agnati, L.F.: Opening address. In: Fuxe, K., Agnati, L.F. (eds.) Receptor-Receptor Interactions. A New Intramembrane Integrative Mechanism, pp. 14\u201318. MacMillan, London (1987)"},{"key":"2_CR41","first-page":"183","volume":"60","author":"L.F. Agnati","year":"1982","unstructured":"Agnati, L.F., Fuxe, K., Zoli, M., Rondanini, C., \u00d6gren, S.O.: New vistas on synaptic plasticity: the receptor mosaic hypothesis of the engram. Med. Biol.\u00a060, 183\u2013190 (1982)","journal-title":"Med. Biol."},{"key":"2_CR42","doi-asserted-by":"publisher","first-page":"3007","DOI":"10.1021\/bi952415g","volume":"35","author":"R. Franco","year":"1996","unstructured":"Franco, R., Casado, V., Ciruela, F., Mallol, J., Lluis, C., Canela, E.I.: The clusterarranged cooperative model: a model that accounts for the kinetics of binding to A1 adenosine receptors. Biochemistry\u00a035, 3007\u20133015 (1996)","journal-title":"Biochemistry"},{"key":"2_CR43","doi-asserted-by":"publisher","first-page":"238","DOI":"10.1016\/S0968-0004(03)00065-3","volume":"28","author":"R. Franco","year":"2003","unstructured":"Franco, R., Canals, M., Marcellino, D., Ferr\u00e9, S., Agnati, L.F., Mallol, J., Casado, V., Ciruela, F., Fuxe, K., Lluis, C., Canela, E.I.: Regulation of heptaspanningmembrane- receptor function by dimerization and clustering. Trends Biochem. Sci.\u00a028, 238\u2013243 (2003)","journal-title":"Trends Biochem. Sci."},{"key":"2_CR44","volume-title":"Oxford Dictionary of Biochemistry and Molecular Biology","year":"1997","unstructured":"Smith, A.D. (ed.): Oxford Dictionary of Biochemistry and Molecular Biology. Oxford University Press, Oxford (1997)"},{"key":"2_CR45","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.lfs.2003.09.028","volume":"74","author":"S.P. Lee","year":"2003","unstructured":"Lee, S.P., O\u2019Dowd, B.F., George, S.R.: Homo- and hetero-oligomerization of G protein-coupled receptors. Life Sci.\u00a074, 173\u2013180 (2003)","journal-title":"Life Sci."},{"key":"2_CR46","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/S0014-5793(03)00453-8","volume":"546","author":"J. Bockaert","year":"2003","unstructured":"Bockaert, J., Marin, P., Dumuis, A., Fagni, L.: The \u2018magic tail\u2019 of G protein-coupled receptors: an anchorage for functional protein networks. FEBS Lett.\u00a0546, 65\u201372 (2003)","journal-title":"FEBS Lett."},{"key":"2_CR47","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1016\/S0165-6147(00)01801-0","volume":"22","author":"G. Milligan","year":"2001","unstructured":"Milligan, G., White, J.H.: Protein-Protein interactions at G-protein-coupled receptors. Trends Phramacol. Sci.\u00a022, 513\u2013518 (2001)","journal-title":"Trends Phramacol. Sci."},{"key":"2_CR48","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1016\/j.tips.2003.09.001","volume":"24","author":"M. Morfis","year":"2003","unstructured":"Morfis, M., Christopoulos, A., Sexton, P.M.: RAMPs: 5 years on, where to now? Trends Phramacol. Sci.\u00a024, 596\u2013601 (2003)","journal-title":"Trends Phramacol. Sci."},{"key":"2_CR49","first-page":"1","volume":"53","author":"S.S.G. Ferguson","year":"2001","unstructured":"Ferguson, S.S.G.: Evolving Concepts in G Protein-Coupled Receptor Endocytosis: The Role in Receptor Desensitisation and Signalling. Pharmacol. Rev.\u00a053, 1\u201324 (2001)","journal-title":"Pharmacol. Rev."},{"key":"2_CR50","first-page":"123","volume":"22","author":"A.D. Howard","year":"2001","unstructured":"Howard, A.D., McAllister, G., Feighner, S.D., Liu, Q., Nargund, R.P., Van der Ploeg, L.H., Patchett, A.A.: Orphan G-protein-coupled receptors and natural ligand discovery. Trends Phramacol. Sci.\u00a022, 123\u2013140 (2001)","journal-title":"Trends Phramacol. Sci."},{"key":"2_CR51","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1098\/rstb.1952.0012","volume":"237","author":"A.M. Turing","year":"1952","unstructured":"Turing, A.M.: The chemical basis of morphogenesis. Philos. Trans. R. Soc. Lond. B\u00a0237, 37\u201372 (1952)","journal-title":"Philos. Trans. R. Soc. Lond. B"},{"key":"2_CR52","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1016\/S0955-0674(99)00085-X","volume":"12","author":"A.S. Edwards","year":"2000","unstructured":"Edwards, A.S., Scott, J.D.: A-kinase anchoring proteins: protein kinase A and beyond. Curr. Op. Cell Biol.\u00a012, 217\u2013221 (2000)","journal-title":"Curr. Op. Cell Biol."},{"key":"2_CR53","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/S0960-9822(00)00419-X","volume":"10","author":"I.D.C. Fraser","year":"2000","unstructured":"Fraser, I.D.C., Cong, M., Kim, J., Rollins, E.N., Daaka, Y., Lefkowitz, R.J., Scott, J.D.: Assembly of an A kinase-anchoring protein-beta(2)-adrenergic receptor complex facilitates receptor phosphorylation and signalling. Curr. Biol.\u00a010, 409\u2013412 (2000)","journal-title":"Curr. Biol."},{"key":"2_CR54","doi-asserted-by":"crossref","first-page":"8315","DOI":"10.1523\/JNEUROSCI.21-21-08315.2001","volume":"21","author":"S.G. Grant","year":"2001","unstructured":"Grant, S.G., Blackstock, W.P.J.: Proteomics in neuroscience: from protein to network. J. Neurosci.\u00a021, 8315\u20138318 (2001)","journal-title":"J. Neurosci."},{"key":"2_CR55","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1097\/00001756-199412300-00004","volume":"6","author":"L.F. Agnati","year":"1994","unstructured":"Agnati, L.F., Cortelli, P., Biagini, G., Bjelke, B., Fuxe, K.: Different classes of volume transmission signals exist in the central nervous system and are affected by metabolic signals, temperature gradients and pressure waves. Neuroreport\u00a06, 9\u201312 (1994)","journal-title":"Neuroreport"},{"key":"2_CR56","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/S0006-8993(98)00498-3","volume":"804","author":"T. Ikezu","year":"1998","unstructured":"Ikezu, T., Ueda, H., Trapp, B.D., Nishiyama, K., Sha, J.F., Volonte, D., Galbiati, F., Byrd, A.L., Bassell, G., Serizawa, H., Lane, W.S., Lisanti, M.P., Okamoto, T.: Affinity-purification and characterization of caveolins from the brain: differential expression of caveolin-1, -2, and -3 in brain endothelial and astroglial cell types. Brain Res.\u00a0804, 177\u2013192 (1998)","journal-title":"Brain Res."},{"key":"2_CR57","first-page":"177","volume-title":"The World of the Cell","year":"2000","unstructured":"Becker, W.M., Kleinsmith, L.J., Hardin, J. (eds.): The World of the Cell, p. 177. The Benjamin, San Francisco (2000)"},{"key":"2_CR58","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/S0166-2236(02)00040-1","volume":"26","author":"G.E. Hardingham","year":"2003","unstructured":"Hardingham, G.E., Bading, H.: The Yin and Yang of NMDA receptor signaling. Trends Neurosci.\u00a026, 81\u201389 (2003)","journal-title":"Trends Neurosci."},{"key":"2_CR59","doi-asserted-by":"publisher","first-page":"698","DOI":"10.1016\/S0092-8674(02)00657-8","volume":"108","author":"A. Barco","year":"2002","unstructured":"Barco, A., Alarcon, J.M., Kandel, E.R.: Expression of Constitutively Active CREB Protein Facilitates the Late Phase of Long-Term Potentiation by Enhancing Synaptic Capture. Cell\u00a0108, 698\u2013703 (2002)","journal-title":"Cell"},{"key":"2_CR60","doi-asserted-by":"publisher","first-page":"13763","DOI":"10.1073\/pnas.231499798","volume":"98","author":"G. Edelman","year":"2001","unstructured":"Edelman, G., Gally, J.A.: Degeneracy and complexity in biological systems. Proc. Natl. Acad. Sci. USA\u00a098, 13763\u201313768 (2001)","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2_CR61","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1126\/science.283.5400.381","volume":"283","author":"U.S. Bhalla","year":"1999","unstructured":"Bhalla, U.S., Iyengar, R.: Emergent Properties of Networks of Biological Signalling Pathways. Science\u00a0283, 381\u2013387 (1999)","journal-title":"Science"},{"key":"2_CR62","unstructured":"von Newmann, J. (ed.): The Computer and the Brain. New Haven CT, Yale University Press (1959)"}],"container-title":["Lecture Notes in Computer Science","Computational Neuroscience: Cortical Dynamics"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-540-27862-7_2.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T03:31:35Z","timestamp":1620012695000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-540-27862-7_2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004]]},"ISBN":["9783540225669","9783540278627"],"references-count":62,"URL":"https:\/\/doi.org\/10.1007\/978-3-540-27862-7_2","relation":{},"ISSN":["0302-9743","1611-3349"],"issn-type":[{"value":"0302-9743","type":"print"},{"value":"1611-3349","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004]]}}}