{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T05:20:54Z","timestamp":1781932854531,"version":"3.54.5"},"publisher-location":"Berlin, Heidelberg","reference-count":55,"publisher":"Springer Berlin Heidelberg","isbn-type":[{"value":"9783540312024","type":"print"},{"value":"9783540312031","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008]]},"DOI":"10.1007\/978-3-540-31203-1_15","type":"book-chapter","created":{"date-parts":[[2009,4,16]],"date-time":"2009-04-16T17:24:30Z","timestamp":1239902670000},"page":"193-202","source":"Crossref","is-referenced-by-count":16,"title":["Cancer of Unknown Primary"],"prefix":"10.1007","author":[{"given":"L. S.","family":"Freudenberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. J.","family":"Rosenbaum-Krumme","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Bockisch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Eberhardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Frilling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"15_CR1","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1148\/radiology.210.1.r99ja48177","volume":"210","author":"O.S. Assar","year":"1999","unstructured":"AAssar OS, Fischbein NJ, Caputo GR, Kaplan MJ, Price DC, Singer MI, Dillon WP, Hawkins RA (1999) Meta-static head and neck cancer: role and usefulness of FDG PET in locating occult primary tumors. Radiology 210:177\u2013181","journal-title":"Radiology"},{"key":"15_CR2","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1200\/JCO.1994.12.6.1272","volume":"12","author":"J.L. Abbruzzese","year":"1994","unstructured":"Abbruzzese JL, Abbruzzese MC, Hess KR, Raber MN, Lenzi R, Frost P (1994) Unknown primary carcinoma: natural history and prognostic factors in 657 consecutive patients. J Clin Oncol 12:1272\u20131280","journal-title":"J Clin Oncol"},{"key":"15_CR3","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1007\/s002590050293","volume":"25","author":"S. Adams","year":"1998","unstructured":"Adams S, Baum RP, Stuckensen T, Bitter K, H\u00f6r G (1998) Prospective comparison of 18F-FDG PET with conventional imaging modalities (CT, MRI, US) in lymph node staging of head and neck cancer. Eur J Nucl Med 25:1255\u20131260","journal-title":"Eur J Nucl Med"},{"key":"15_CR4","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1097\/00006231-200310000-00008","volume":"24","author":"J.L. Alberini","year":"2003","unstructured":"Alberini JL, Belhocine T, Hustinx R, Daenen F, Rigo P (2003) Whole-body positron emission tomography using fluorodeoxyglucose in patients with metastases of unknown primary tumours (CUP syndrome). Nucl Med Commun 24:1081\u20131086","journal-title":"Nucl Med Commun"},{"key":"15_CR5","first-page":"1339","volume":"43","author":"G. Antoch","year":"2002","unstructured":"Antoch G, Freudenberg LS, Egelhof T, Stattaus J, Jentzen W, Debatin JF, Bockisch A (2002) Focal tracer uptake: a potential artifact in contrast-enhanced dual-modality PET\/CT scans. J Nucl Med 43:1339\u20131342","journal-title":"J Nucl Med"},{"key":"15_CR6","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1148\/radiol.2303021287","volume":"230","author":"G. Antoch","year":"2004","unstructured":"Antoch G, Kuehl H, Kanja J, Lauenstein TC, Schneemann H, Hauth E, Jentzen W, Beyer T, Goehde SC, Debatin JF (2004a) Dual-modality PET\/CT scanning with negative oral contrast agent to avoid artifacts: introduction and evaluation. Radiology 230:879\u2013885","journal-title":"Radiology"},{"key":"15_CR7","doi-asserted-by":"publisher","first-page":"3199","DOI":"10.1001\/jama.290.24.3199","volume":"290","author":"G. Antoch","year":"2003","unstructured":"Antoch G, Vogt FM, Freudenberg LS, Nazaradeh F, Goehde SC, Barkhausen J, Dahmen G, Bockisch A, Debatin JF, Ruehm SG (2003) Whole-body dual-modality PET\/ CT and whole-body MRI for tumor staging in oncology. JAMA 290:3199\u20133206","journal-title":"JAMA"},{"key":"15_CR8","doi-asserted-by":"publisher","first-page":"4357","DOI":"10.1200\/JCO.2004.08.120","volume":"22","author":"G. Antoch","year":"2004","unstructured":"Antoch G, Saoudi N, Kuehl H, Dahmen G, Mueller SP, Beyer T, Bockisch A, Debatin JF, Freudenberg LS (2004b) Accuracy of whole-body dual-modality fluorine-18-2-fluoro-2-deoxy-D-glucose positron emission tomography and computed tomography (FDG-PET\/CT) for tumor staging in solid tumors: comparison with CT and PET. J Clin Oncol 22:4357\u20134368","journal-title":"J Clin Oncol"},{"key":"15_CR9","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1007\/s00259-002-1097-6","volume":"30","author":"T. Beyer","year":"2003","unstructured":"Beyer T, Antoch G, Blodgett T, Freudenberg LF, Akhurst T, Mueller S (2003) Dual-modality PET\/CT imaging: the effect of respiratory motion on combined image quality in clinical oncology. Eur J Nucl Med Mol Imaging 30:588\u2013596","journal-title":"Eur J Nucl Med Mol Imaging"},{"issue":"Suppl1","key":"15_CR10","first-page":"25S","volume":"45","author":"T. Beyer","year":"2004","unstructured":"Beyer T, Antoch G, Muller S, Egelhof T, Freudenberg LS, Debatin J, Bockisch A (2004) Acquisition protocol considerations for combined PET\/CT imaging. J Nucl Med 45 [Suppl 1]:25S\u201335S","journal-title":"J Nucl Med"},{"key":"15_CR11","first-page":"429","volume":"46","author":"B. T","year":"2005","unstructured":"Beyer T, Antoch G, Bockisch A, Stattaus J (2005a) Optimized intravenous contrast administration for diagnostic whole-body 18F-FDG PET\/CT. J Nucl Med 46:429\u2013435","journal-title":"J Nucl Med"},{"key":"15_CR12","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1007\/s00259-005-1879-8","volume":"32","author":"T. Beyer","year":"2005","unstructured":"Beyer T, Rosenbaum S, Veit P, Stattaus J, Muller SP, Difilippo FP, Schoder H, Mawlawi O, Roberts F, Bockisch A, Kuhl H (2005b) Respiration artifacts in whole-body (18)F-FDG PET\/CT studies with combined PET\/CT tomographs employing spiral CT technology with 1 to 16 detector rows. Eur J Nucl Med Mol Imaging 32:1429\u20131439","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"15_CR13","first-page":"816","volume":"41","author":"K.H. Bohuslavizki","year":"2000","unstructured":"Bohuslavizki KH, Klutmann S, Kroger S, Sonnemann U, Buchert R, Werner JA, Mester J, Clausen M (2000) FDG PET detection of unknown primary tumors. J Nucl Med 41:816\u2013822","journal-title":"J Nucl Med"},{"key":"15_CR14","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1016\/S0901-5027(05)80829-X","volume":"26","author":"J.W. Braams","year":"1997","unstructured":"Braams JW, Pruim J, Kole AC, Nikkeis PG, Vaalburg W, Vermey A, Roodenburg JL (1997) Detection of unknown primary head and neck tumors by positron emission tomography. Int J Oral Maxillofac Surg 26:112\u2013115","journal-title":"Int J Oral Maxillofac Surg"},{"key":"15_CR15","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1055\/s-0038-1623918","volume":"43","author":"U. Buell","year":"2004","unstructured":"Buell U, Wieres FJ, Schneider W, Reinartz P (2004) 18FDG-PET in 733 consecutive patients with or without side-by-side CT evaluation: Analysis of 921 lesions. Nuklearmedizin 43:210\u2013216","journal-title":"Nuklearmedizin"},{"key":"15_CR16","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1007\/s00259-002-1055-3","volume":"30","author":"C. Cohade","year":"2003","unstructured":"Cohade C, Osman M, Marshall LN, Wahl RN (2003) PET-CT: accuracy of PET and CT spatial registration of lung lesions. Eur J Nucl Med Mol Imaging 30: 721\u2013726","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"15_CR17","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/0305-7372(94)90024-8","volume":"20","author":"G. Daugaard","year":"1994","unstructured":"Daugaard G (1994) Unknown primary tumours. Cancer Treatment Rev 20:119\u2013147","journal-title":"Cancer Treatment Rev"},{"key":"15_CR18","first-page":"1301","volume":"44","author":"R.C. Delgado-Bolton","year":"2003","unstructured":"Delgado-Bolton RC, Fernandez-Perez C, Gonzalez-Mate A, Carreras JL (2003) Meta-analysis of the performance of 18F-FDG PET in primary tumor detection in unknown primary tumors. J Nucl Med 44:1301\u20131314","journal-title":"J Nucl Med"},{"key":"15_CR19","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1001\/archotol.126.12.1457","volume":"126","author":"E. Martino Di","year":"2000","unstructured":"Di Martino E, Nowak B, Hassan HA, Hausmann R, Adam G, Buell U, Westhofen M (2000) Diagnosis and staging of head and neck cancer. Arch Otolaryngol Head Neck Surg 126:1457\u20131461","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"15_CR20","first-page":"441","volume":"37","author":"H. Engel","year":"1996","unstructured":"Engel H, Steinert H, Buck A, Berthold T, Huch Boni RA, von Schulthess GK (1996) Whole-body PET: physiologic and artifactual fluoro-deoxyglucose accumulations. J Nucl Med 37: 441\u2013446","journal-title":"J Nucl Med"},{"key":"15_CR21","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1159\/000084632","volume":"14","author":"L.S. Freudenberg","year":"2005","unstructured":"Freudenberg LS, Fischer M, Antoch G, Jentzen W, Gutzeit A, Rosenbaum SJ, Bockisch A, Egelhof T (2005) Dual modality of 18F-fluorodeoxyglucose-positron emission tomography\/computed tomography in patients with cervical carcinoma of unknown primary. Med PrincPract 14:155\u2013160","journal-title":"Med PrincPract"},{"key":"15_CR22","first-page":"1","volume":"42","author":"S.S. Gambhir","year":"2001","unstructured":"Gambhir SS, Czernin J, Schwimmer J, Silverman DH, Coleman RE, Phelps ME (2001) A tabulated summary of the FDG PET literature. J Nucl Med 42 [5 Suppl]:1\u201393","journal-title":"J Nucl Med"},{"key":"15_CR23","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1007\/s00259-001-0721-1","volume":"29","author":"G.W. Goerres","year":"2002","unstructured":"Goerres GW, Hany TF, Kamel E, von Schulthess GK, Buck A (2002a) Head and neck imaging with PET and PET\/CT: artefacts from dental metallic implants. Eur J Nucl Med 29:367\u2013370","journal-title":"Eur J Nucl Med"},{"key":"15_CR24","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1007\/s00259-001-0710-4","volume":"29","author":"G.W. Goerres","year":"2002","unstructured":"Goerres GW, Kamel E, Heidelberg TN, Schwitter MR, Burger C, von Schulthess GK (2002b) PET\/CT image co-registration in the thorax: influence of respiration. Eur J Nucl Med Mol Imaging 29:351\u2013360","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"15_CR25","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1007\/s00330-002-1720-8","volume":"13","author":"G.W. Goerres","year":"2003","unstructured":"Goerres GW, Burger C, Schwitter MR, Heidelberg TN, Seifert B, von Schulthess GK (2003) PET\/CT of the abdomen: optimizing the patient breathing pattern. Eur Radiol 13:734\u2013739","journal-title":"Eur Radiol"},{"key":"15_CR26","doi-asserted-by":"publisher","DOI":"10.1007\/b97251","volume-title":"AJCC cancer staging manual","author":"L. Greene","year":"2002","unstructured":"Greene L (2002) AJCC cancer staging manual. Springer, New York"},{"key":"15_CR27","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1002\/(SICI)1097-0142(19990701)86:1<114::AID-CNCR16>3.0.CO;2-E","volume":"86","author":"K.M. Greven","year":"1999","unstructured":"Greven KM, Keyes JW Jr, Williams DW III, McGuirt WF, Joyce WT III (1999) Occult primary tumors of the head and neck: lack of benefit from positron emission tomography imaging with 2-[F-18]fluoro-2-deoxy-D-glucose. Cancer 86:114\u2013118","journal-title":"Cancer"},{"key":"15_CR28","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1097\/00005537-199906000-00007","volume":"109","author":"M.M. Hanasono","year":"1999","unstructured":"Hanasono MM, Kunda LD, Segall GM, Ku GH, Terris DJ (1999) Uses and limitations of FDG positron emission tomography in patients with head and neck cancer. Laryngoscope 109:880\u2013885","journal-title":"Laryngoscope"},{"key":"15_CR29","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1053\/snuc.2003.127309","volume":"33","author":"B.F. Hutton","year":"2003","unstructured":"Hutton BF, Braun M (2003) Software for image registration: algorithms, accuracy, efficacy. Sem Nucl Med 33:180\u2013192","journal-title":"Sem Nucl Med"},{"key":"15_CR30","doi-asserted-by":"publisher","first-page":"2009","DOI":"10.1097\/00005537-200211000-00018","volume":"112","author":"J. Johansen","year":"2002","unstructured":"Johansen J, Eigtved A, Buchwald C, Theilgaard SA, Hansen HS (2002) Implication of 18F-fluoro-2-deoxy-Dglucose positron emission tomography on management of carcinoma of unknown primary in the head and neck: a Danish cohort study. Laryngoscope 112:2009\u20132014","journal-title":"Laryngoscope"},{"key":"15_CR31","first-page":"267","volume":"38","author":"W.H. Knapp","year":"1999","unstructured":"Knapp WH (1999) Leitlinie zur Tumordarstellung mit (F-18)-Fluordeoxyglukose (FDG). Nuklearmedizin 38:267\u2013269","journal-title":"Nuklearmedizin"},{"key":"15_CR32","doi-asserted-by":"publisher","first-page":"1160","DOI":"10.1002\/(SICI)1097-0142(19980315)82:6<1160::AID-CNCR22>3.0.CO;2-3","volume":"82","author":"A.C. Kole","year":"1998","unstructured":"Kole AC, Nieweg OE, Pruim J, Hoekstra HJ, Koops HS, Roodenburg JL, Vaalburg W, Vermey A (1998) Detection of unknown occult primary tumors using positron emission tomography. Cancer 82:1160\u20131166","journal-title":"Cancer"},{"key":"15_CR33","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1097\/00006231-200512000-00003","volume":"26","author":"H. Kolesnikov-Gauthier","year":"2005","unstructured":"Kolesnikov-Gauthier H, Levy E, Merlet P, Kirova J, Syrota A, Carpentier P, Meignan M, Piedbois P (2005) FDG PET in patients with cancer of an unknown primary. Nucl Med Commun 26:1059\u20131066","journal-title":"Nucl Med Commun"},{"key":"15_CR34","doi-asserted-by":"publisher","first-page":"1076","DOI":"10.1016\/S0959-8049(99)00077-5","volume":"35","author":"U. Lassen","year":"1999","unstructured":"Lassen U, Daugaard G, Eigtved A, Damgaard K, Friberg L (1999) 18F-FDG whole body positron emission tomography (PET) in patients with unknown primary tumours (UPT). Eur J Cancer 35:1076\u20131082","journal-title":"Eur J Cancer"},{"key":"15_CR35","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1148\/radiol.2331030777","volume":"233","author":"T.C. Lauenstein","year":"2004","unstructured":"Lauenstein TC, Goehde SC, Herborn CU, Goyen M, Oberhoff C, Debatin JF, Ruehm SG, Barkhausen J (2004) Whole-body MR imaging: evaluation of patients for metastases. Radiology 233:139\u2013148","journal-title":"Radiology"},{"key":"15_CR36","first-page":"1","volume":"34","author":"P. Lindholm","year":"1993","unstructured":"Lindholm P, Minn H, Leskinen-Kallio S, Bergman J, Ruotsalainen U, Joensuu H (1993) Influence of the blood glucose concentration on FDG uptake in cancer-a PET study. J Nucl Med 34:1\u20136","journal-title":"J Nucl Med"},{"key":"15_CR37","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/S1095-0397(00)00053-4","volume":"3","author":"M. Lonneux","year":"2000","unstructured":"Lonneux M, Reffad AM (2000) Metastases from unknown primary tumor: PET-FDG as initial diagnostic procedure? Clin Positron Imaging 3:137\u2013141","journal-title":"Clin Positron Imaging"},{"key":"15_CR38","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1089\/108497803321269322","volume":"18","author":"P. Mantaka","year":"2003","unstructured":"Mantaka P, Baum RP, Hertel A, Adams S, Niessen A, Sengupta S, Hor G (2003) PET with 2-[F-18]-fluoro-2-deoxy-D-glucose (FDG) in patients with cancer of unknown primary (CUP): influence on patients\u2019 diagnostic and therapeutic management. Cancer Biother Radiopharm 18:47\u201358","journal-title":"Cancer Biother Radiopharm"},{"key":"15_CR39","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1007\/s00259-004-1734-3","volume":"32","author":"C. Nanni","year":"2005","unstructured":"Nanni C, Rubello D, Castellucci P, Farsad M, Franchi R, Toso S, Barile C, Rampin L, Nibale O, Fanti S (2005) Role of 18F-FDG PET-CT imaging for the detection of an unknown primary tumour: preliminary results in 21 patients. Eur J Nucl Med Mol Imaging 32:589\u2013592","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"15_CR40","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/S0360-3016(01)01462-6","volume":"50","author":"C. Nieder","year":"2001","unstructured":"Nieder C, Gregoire V, Ang KK (2001) Cervical lymph node metastases from occult squamous cell carcinoma: cut down a tree to get an apple? Int J Radiat Oncol Biol Phys 50:727\u2013733","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"15_CR41","doi-asserted-by":"publisher","first-page":"1578","DOI":"10.1097\/00005537-199810000-00029","volume":"108","author":"P. Paulus","year":"1998","unstructured":"Paulus P, Sambon A, Vivegnis D, Hustinx R, Moreau P, Collignon J, Deneufbourg JM, Rigo P (1998) 18FDG-PET for the assessment of primary head and neck tumors: clinical, computed tomography, and histopathological correlation in 38 patients. Laryngoscope 108:1578\u20131583","journal-title":"Laryngoscope"},{"key":"15_CR42","first-page":"15","volume":"50","author":"E. Pelosi","year":"2006","unstructured":"Pelosi E, Pennone M, Deandreis D, Douroukas A, Mancini M, Bisi G (2006) Role of whole body positron emission tomography\/computed tomography scan with 18F-fluorodeoxyglucose in patients with biopsy proven tumor metastases from unknown primary site. Q J Nucl Med Mol Imaging 50:15\u201322","journal-title":"Q J Nucl Med Mol Imaging"},{"key":"15_CR43","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1007\/PL00002363","volume":"177","author":"D. Rades","year":"2001","unstructured":"Rades D, Kuhnel G, Wildfang I, Borner AR, Knapp W, Karstens JH (2001a) The value of positron emission tomography (PET) in the treatment of patients with cancer of unknown primary (CUP). Strahlenther Onkol 177:525\u2013529","journal-title":"Strahlenther Onkol"},{"key":"15_CR44","doi-asserted-by":"publisher","first-page":"1605","DOI":"10.1023\/A:1013107732572","volume":"12","author":"D. Rades","year":"2001","unstructured":"Rades D, Kuhnel G, Wildfang I, Borner AR, Schmoll HJ, Knapp W (2001b) Localised disease in cancer of unknown primary (CUP): the value of positron emission tomography (PET) for individual therapeutic management. Ann Oncol 12:1605\u20131609","journal-title":"Ann Oncol"},{"key":"15_CR45","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.1007\/s00259-002-0819-0","volume":"29","author":"G. Regelink","year":"2002","unstructured":"Regelink G, Brouwer J, de Bree R, Pruim J, van der Laan BF, Vaalburg W, Hoekstra OS, Comans EF, Vissink A, Leemans CR, Roodenburg JL (2002) Detection of unknown primary tumors and distant metastases in patients with cervical metastases: value of FDG-PET versus conventional modalities. Eur J Nucl Med Mol Imaging 29:1024\u20131030","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"15_CR46","doi-asserted-by":"publisher","first-page":"1456","DOI":"10.1007\/s00259-004-1593-y","volume":"31","author":"P. Reinartz","year":"2004","unstructured":"Reinartz P, Wieres FJ, Schneider W, Schur A, Buell U (2004) Side-by-side reading of PET and CT scans in oncology: which patients might profit from integrated PET\/CT? Eur J Nucl Med Mol Imaging 31:1456\u20131461","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"15_CR47","doi-asserted-by":"publisher","first-page":"1707","DOI":"10.1007\/s002590100626","volume":"28","author":"S.N. Reske","year":"2001","unstructured":"Reske SN, Kotzerke J (2001) FDG-PET for clinical use. Results of the 3rd German Interdisciplinary Consensus Conference, \u00abOnko-PET III\u00bb, 21 July and 19 September 2000. Eur J Nucl Med 28:1707\u20131723","journal-title":"Eur J Nucl Med"},{"key":"15_CR48","first-page":"214","volume":"5","author":"A.A. Safa","year":"1999","unstructured":"Safa AA, Tran LM, Rege S, Brown CV, Mandelkern MA, Wang MB, Sadeghi A, Juillard G (1999) The role of positron emission tomography in occult primary head and neck cancers. Cancer J Sci Am 5:214\u2013218","journal-title":"Cancer J Sci Am"},{"key":"15_CR49","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.1007\/s003300050579","volume":"8","author":"C. Schiepers","year":"1998","unstructured":"Schiepers C, H\u00f6h CK (1998) Positron emission tomography as a diagnostic tool in oncology. Eur Radiol 8:1481\u20131494","journal-title":"Eur Radiol"},{"key":"15_CR50","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1055\/s-2005-870509","volume":"85","author":"K. Schneider","year":"2006","unstructured":"Schneider K, Aschoff P, Bihl H, Hagen R (2006a) The integrated PET\/CT: technological advance in diagnostics of head and neck recurrences and CUP? Laryngorhinootologie 85:179\u2013183","journal-title":"Laryngorhinootologie"},{"key":"15_CR51","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1055\/s-2006-925297","volume":"85","author":"K. Schneider","year":"2006","unstructured":"Schneider K, Hrasky A, Aschoff P, Bihl H, Hagen R (2006b) Significance of PET and integrated PET\/CT in the diagnostics of occult primary tumors. Laryngorhinootologie. 85:819\u2013823","journal-title":"Laryngorhinootologie"},{"key":"15_CR52","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1007\/s11307-005-4114-x","volume":"7","author":"C.L. Scott","year":"2005","unstructured":"Scott CL, Kudaba I, Stewart JM, Hicks RJ, Rischin D (2005) The utility of 2-deoxy-2-[F-18]fluoro-D-glucose positron emission tomography in the investigation of patients with disseminated carcinoma of unknown primary origin. Mol Imaging Biol 7:236\u2013243","journal-title":"Mol Imaging Biol"},{"key":"15_CR53","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/S0959-8049(01)00378-1","volume":"38","author":"A.J. Wouw Van de","year":"2002","unstructured":"Van de Wouw AJ, Janssen-Heijnen ML, Coebergh JW, Hillen HF (2002) Epidemiology of unknown primary tumors: incidence and population-based survival of 1285 patients in Southeast Netherlands, 1984-1992. Eur J Cancer 38:409\u2013413","journal-title":"Eur J Cancer"},{"key":"15_CR54","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1093\/annonc\/mdg068","volume":"14","author":"A.J. Wouw Van de","year":"2003","unstructured":"Van de Wouw AJ, Jansen RL, Speel EJ, Hillen HF (2003) The unknown biology of the unknown primary tumour: a literature review. Ann Oncol 14:191\u2013196","journal-title":"Ann Oncol"},{"key":"15_CR55","unstructured":"Warburg O, Wind F, Neglers E (1930) On the metabolism of tumors in the body. Constable, London, pp 254\u2013270"}],"container-title":["Recent Results in Cancer Research","PET in Oncology"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-540-31203-1_15.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T03:37:49Z","timestamp":1620013069000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-540-31203-1_15"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"ISBN":["9783540312024","9783540312031"],"references-count":55,"URL":"https:\/\/doi.org\/10.1007\/978-3-540-31203-1_15","relation":{},"ISSN":["0080-0015"],"issn-type":[{"value":"0080-0015","type":"print"}],"subject":[],"published":{"date-parts":[[2008]]}}}