{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T23:41:09Z","timestamp":1759189269745},"publisher-location":"Berlin, Heidelberg","reference-count":19,"publisher":"Springer Berlin Heidelberg","isbn-type":[{"type":"print","value":"9783540727170"},{"type":"electronic","value":"9783540727187"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008]]},"DOI":"10.1007\/978-3-540-72718-7_8","type":"book-chapter","created":{"date-parts":[[2008,7,14]],"date-time":"2008-07-14T16:46:47Z","timestamp":1216054007000},"page":"167-175","source":"Crossref","is-referenced-by-count":13,"title":["Contrast Agents: X-ray Contrast Agents and Molecular Imaging \u2013 A Contradiction?"],"prefix":"10.1007","author":[{"given":"Ulrich","family":"Speck","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"8_CR1_Ref","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1055\/s-0029-1226625","volume":"93","author":"W B \u00f6rner","year":"1960","unstructured":"B \u00f6rner W, Moll E, Schneider P, Stucke K (1960) Zur Problematik der Thorotrastsch \u00e4den. Klinische und radiologische Untersuchungen zum Verhalten von Thorium und seiner Zerfallsprodukte im Organismus. Rofo 93:287-297","journal-title":"Rofo"},{"volume-title":"Textbook of contrast media","year":"1999","unstructured":"Dawson P, Cosgrove DO, Grainger RG (eds) (1999) Textbook of contrast media. Isis Medical Media, Oxford","key":"8_CR2_Ref"},{"key":"8_CR3_Ref","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1002\/j.1552-4604.1978.tb01558.x","volume":"18","author":"LT Difazio","year":"1978","unstructured":"Difazio LT, Singhvi SM, Heald AF, McKinstry DN, Brosman SA, Gillenwater JY, Willard DA (1978) Pharmacokinetics of iodamide in normal subjects and in patients with renal impairment. J Clin Pharmacol 18:35-41","journal-title":"J Clin Pharmacol"},{"key":"8_CR4_Ref","first-page":"31","volume-title":"Contrast media in practice","author":"W Krause","year":"1998","unstructured":"Krause W, Schuhmann-Gampieri G (1998) Pharmacokinetics of contrast media. In: Dawson P, Clauss W (eds) Contrast media in practice. Springer, Berlin Heidelberg New York, pp 31-39"},{"issue":"(Suppl 1)","key":"8_CR5_Ref","doi-asserted-by":"publisher","first-page":"S6","DOI":"10.1016\/S1076-6332(98)80044-5","volume":"5","author":"P Leander","year":"1998","unstructured":"Leander P, H \u00f6glund P, Kloster Y (1998) New liposomal liver-specific contrast agent for CT: first human phase I clinical trial assessing efficacy and safety. Acad Radiol 5(Suppl 1):S6-S8","journal-title":"Acad Radiol"},{"key":"8_CR6_Ref","doi-asserted-by":"publisher","first-page":"1670","DOI":"10.1002\/jps.2600661204","volume":"66","author":"SK Lin","year":"1977","unstructured":"Lin SK, Moss AA, Riegelman S (1977) Iodipamide kinetics: Capacity-limited biliary excretion with simultaneous pseudo-first-order renal excretion. J Pharm Sci 66:1670-1674","journal-title":"J Pharm Sci"},{"key":"8_CR7_Ref","doi-asserted-by":"publisher","first-page":"293","DOI":"10.2307\/3579941","volume":"151","author":"U Martling","year":"1999","unstructured":"Martling U, Mattsson A, Travis LB, Holm LE, Hall P (1999) Mortality after long-term exposure to radioactive Thorotrast: a forty-year follow-up survey in Sweden. Radiat Res 151:293-299","journal-title":"Radiat Res"},{"unstructured":"Contrast Agents: X-ray Contrast Agents and Molecular Imaging - A Contradiction?175","key":"8_CR8_Ref"},{"key":"8_CR9_Ref","first-page":"892","volume":"41","author":"O Mitsutomo","year":"1930","unstructured":"Mitsutomo O (1930) Klinische Anwendung der \u201cLienographie\u201d, einer neuen Methode zur r \u00f6ntgenologischen Darstellung von Milz und Leber. Rofo 41:892-898","journal-title":"Rofo"},{"key":"8_CR10_Ref","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1007\/978-3-642-68584-2_75","volume-title":"Contrast media in radiology Appraisal and prospects","author":"W M\u00fctzel","year":"1982","unstructured":"M\u00fctzel W, Wegener OH, Souchon R, Weinmann H-J (1982) Water-soluble contrast agents for com-puted tomography of the liver: experimental studies in dog. In: Amiel M, Moreau JF (eds) Contrast media in radiology Appraisal and prospects. Springer, Berlin Heidelberg New York, pp 320-323"},{"issue":"Suppl","key":"8_CR11_Ref","doi-asserted-by":"crossref","first-page":"6H","DOI":"10.1016\/S0002-9149(00)01094-8","volume":"86","author":"JL Orford","year":"2000","unstructured":"Orford JL, Selwyn AP, Ganz P, Popma JJ, Rogers C (2000) The comparative pathobiology of atherosclerosis and restenosis. Am J Cardiol 86(Suppl):6H-11H","journal-title":"Am J Cardiol"},{"key":"8_CR12_Ref","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1097\/00004424-199407000-00005","volume":"29","author":"U Schmiedl","year":"1994","unstructured":"Schmiedl U, Schmoll K, Horn J, Speck U, Freeny P (1994) Imaging of exocrine pancreatic function investigation of the biovailability of weak organic acids as potential pancreatic contrast agents for computed tomography. Invest Radiol 29:689-694","journal-title":"Invest Radiol"},{"key":"8_CR13_Ref","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1148\/radiology.202.2.9015065","volume":"2002","author":"SA Schmitz","year":"1997","unstructured":"Schmitz SA, H \u00e4berle JH, Balzer T, Shamsi K, Boese-Landgraf J, Wolf K-J (1997) Detection of focal liver lesions: CT of the hepatobiliary system with gadoxetic acid disodium, or Gd-EOB-DTPA. Radiology 2002:399-405","journal-title":"Radiology"},{"key":"8_CR14_Ref","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1148\/radiol.2363051160","volume":"236","author":"M Thakur","year":"2005","unstructured":"Thakur M, Lentle BC (2005) Report of a summit on molecular imaging. Radiology 236:753-755","journal-title":"Radiology"},{"key":"8_CR15_Ref","first-page":"307","volume":"8","author":"K Urich","year":"1991","unstructured":"Urich K, Speck U (1991) Biliary excretion of contrast media. Progr Pharmacol Clin Pharmacol 8:307-322","journal-title":"Progr Pharmacol Clin Pharmacol"},{"key":"8_CR16_Ref","volume-title":"Successes and failures in the development of contrast media","author":"K Urich","year":"1995","unstructured":"Urich K (1995) Successes and failures in the development of contrast media. Blackwell, Berlin"},{"key":"8_CR17_Ref","first-page":"6449","volume":"49","author":"P Vaupel","year":"1989","unstructured":"Vaupel P, Kallinowski F, Okunieff P (1989) Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Research 49:6449-6465","journal-title":"Cancer Research"},{"key":"8_CR18_Ref","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1097\/00004424-198101000-00008","volume":"16","author":"MR Violante","year":"1981","unstructured":"Violante MR, Mare K, Fischer HW (1981) Biodistribution of a particulate hepatolienographic CT contrast agent: A study of iodipamide ethyl ester in the rat. Invest Radiol 16:40-45","journal-title":"Invest Radiol"},{"key":"8_CR19_Ref","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1148\/radiology.216.3.r00se43865","volume":"216","author":"JP Weichert","year":"2000","unstructured":"Weichert JP, Lee FT, Chosy SG, Longino MA, Kuhlman JE, Helsey DE, Leverson GE (2000) Com-bined hepatocyte-selective and blood-pool contrast agents for the CT detection of experimental liver tumors in rabbits. Radiology 216:865-871","journal-title":"Radiology"}],"container-title":["Handbook of Experimental Pharmacology","Molecular Imaging I"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-540-72718-7_8.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T05:46:50Z","timestamp":1619502410000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-540-72718-7_8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"ISBN":["9783540727170","9783540727187"],"references-count":19,"URL":"https:\/\/doi.org\/10.1007\/978-3-540-72718-7_8","relation":{},"ISSN":["0171-2004"],"issn-type":[{"type":"print","value":"0171-2004"}],"subject":[],"published":{"date-parts":[[2008]]}}}