{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T11:26:49Z","timestamp":1773660409754,"version":"3.50.1"},"publisher-location":"Berlin, Heidelberg","reference-count":62,"publisher":"Springer Berlin Heidelberg","isbn-type":[{"value":"9783540798842","type":"print"},{"value":"9783540798859","type":"electronic"}],"license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009]]},"DOI":"10.1007\/978-3-540-79885-9_19","type":"book-chapter","created":{"date-parts":[[2008,12,18]],"date-time":"2008-12-18T22:49:14Z","timestamp":1229640554000},"page":"385-402","source":"Crossref","is-referenced-by-count":29,"title":["Design, Synthesis and Assaying of Potential Aquaporin Inhibitors"],"prefix":"10.1007","author":[{"given":"Rose","family":"Haddoub","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"R\u00fctzler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A\u00e9lig","family":"Robin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine L.","family":"Flitsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"19_CR1_19","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1016\/0005-2736(80)90118-2","volume":"597","author":"TM Allen","year":"1980","unstructured":"Allen TM, Cleland LG (1980) Serum-induced leakage of liposome contents. Biochim Biophys Acta 597:418\u2013426","journal-title":"Biochim Biophys Acta"},{"key":"19_CR2_19","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1085\/jgp.58.4.413","volume":"58","author":"CM Armstrong","year":"1971","unstructured":"Armstrong CM (1971) Interaction of tetraethyl ammonium ion derivatives with the potassium channels of giant axons. J Gen Physiol 58:413\u2013437","journal-title":"J Gen Physiol"},{"key":"19_CR3_19","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/S0026-895X(24)26513-5","volume":"57","author":"HL Brooks","year":"2000","unstructured":"Brooks HL, Regan JW, Yool AJ (2000) Inhibition of aquaporin-1 water permeability by tetraethyl ammonium: involvement of the loop E pore region. Mol Pharmacol 57:1021\u20131026","journal-title":"Mol Pharmacol"},{"key":"19_CR4_19","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/0003-2697(88)90412-5","volume":"172","author":"RF Chen","year":"1988","unstructured":"Chen RF, Knutson JR (1988) Mechanism of fluorescence concentration quenching of carboxyflu-orescein in liposomes: energy transfer to nonfluorescent dimers. Anal Biochem 172:61\u201377","journal-title":"Anal Biochem"},{"key":"19_CR5_19","doi-asserted-by":"publisher","first-page":"1507","DOI":"10.1128\/AEM.72.2.1507-1514.2006","volume":"72","author":"MJ Daniels","year":"2006","unstructured":"Daniels MJ, Wood MR, Yeager M (2006) In vivo functional assay of a recombinant aquaporin inPichia pastoris. Appl Environ Microbiol 72:1507\u20131514","journal-title":"Appl Environ Microbiol"},{"key":"19_CR6_19","first-page":"14207","volume":"281","author":"FJ Detmers","year":"2006","unstructured":"Detmers FJ, de Groot BL, Muller EM, Hinton A, Konings IB, Sze M, Flitsch SL, Grubmuller H,Deen PM (2006) Quaternary ammonium compounds as water channel blockers. Specificity,potency, and site of action. J Biol Chem 281:14207\u201314214","journal-title":"Specificity,potency, and site of action. J Biol Chem"},{"key":"19_CR7_19","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.ab.2005.03.033","volume":"342","author":"J Gao","year":"2005","unstructured":"Gao J, Yu H, Song Q, Li X (2005) Establishment of HEK293 cell line expressing green fluorescent protein-aquaporin-1 to determine osmotic water permeability. Anal Biochem 342:53\u201358","journal-title":"Anal Biochem"},{"key":"19_CR8_19","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1016\/j.ab.2006.01.003","volume":"350","author":"J Gao","year":"2006","unstructured":"Gao J, Wang X, Chang Y, Zhang J, Song Q, Yu H, Li X (2006) Acetazolamide inhibits osmotic water permeability by interaction with aquaporin-1. Anal Biochem 350:165\u2013170","journal-title":"Anal Biochem"},{"key":"19_CR9_19","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1016\/0896-6273(95)90252-X","volume":"14","author":"SE Gordon","year":"1995","unstructured":"Gordon SE, Zagotta WN (1995) A Histidine residue associated with the gate of the cyclic nucleotide-activated channels in rod photoreceptors. Neuron 14:177\u2013183","journal-title":"Neuron"},{"key":"19_CR10_19","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.neuroscience.2005.07.027","volume":"136","author":"E Gunnarson","year":"2005","unstructured":"Gunnarson E, Axehult G, Baturina G, Zelenin S, Zelenina M, Aperia A (2005) Lead induces increased water permeability in astrocytes expressing aquaporin 4. Neuroscience 136:105\u2013114","journal-title":"Neuroscience"},{"key":"19_CR11_19","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1023\/A:1016832027325","volume":"12","author":"S Hamann","year":"2002","unstructured":"Hamann S, Kiilgaard JF, Litman T, Alvarez-Leefmans FJ, Winther BR, Zeuthen T (2002) Measurement of cell volume changes by fluorescence self-quenching. J Fluoresc 12:139\u2013145","journal-title":"J Fluoresc"},{"key":"19_CR12_19","doi-asserted-by":"publisher","first-page":"15493","DOI":"10.1074\/jbc.C500028200","volume":"280","author":"M Hara-Chikuma","year":"2005","unstructured":"Hara-Chikuma M, Sohara E, Rai T, Ikawa M, Okabe M, Sasaki S, Uchida S, Verkman AS (2005) Progressive adipocyte hypertrophy in aquaporin-7-deficient mice: adipocyte glycerol permeability as a novel regulator of fat accumulation. J Biol Chem 280:15493\u201315496","journal-title":"J Biol Chem"},{"key":"19_CR13_19","doi-asserted-by":"publisher","first-page":"10993","DOI":"10.1073\/pnas.0503291102","volume":"102","author":"T Hibuse","year":"2005","unstructured":"Hibuse T, Maeda N, Funahashi T, Yamamoto K, Nagasawa A, Mizunoya W, Kishida K, Inoue K, Kuriyama H, Nakamura T, Fushiki T, Kihara S, Shimomura I (2005) Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase. Proc Natl Acad Sci U S A 102:10993\u201310998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"19_CR14_19","doi-asserted-by":"publisher","first-page":"1670","DOI":"10.1016\/j.bmcl.2006.12.010","volume":"17","author":"VJ Huber","year":"2007","unstructured":"Huber VJ, Tsujita M, Yamazaki M, Sakimura K, Nakada T (2007) Identification of arylsulfon-amides as AQP4 inhibitor. Bioorg Med Chem Lett 17:1670\u20131273","journal-title":"Bioorg Med Chem Lett"},{"key":"19_CR15_19","doi-asserted-by":"crossref","unstructured":"Huber VJ, Tsujita M, Nakada T (2008a) Identification of aquaporin 4 inhibitors using in vitro and in silico methods. Bioorg Med Chem. doi 10.1016\/j.bmc.2007.12.038","DOI":"10.1016\/j.bmc.2007.12.040"},{"key":"19_CR16_19","doi-asserted-by":"crossref","unstructured":"Huber VJ, Tsujita M, Kwee IL, Nakada T (2008b) Inhibition of Aquaporin 4 by antiepileptic drugs. Bioorg Med Chem. doi:10.1016\/j.bmc.2007.12.040","DOI":"10.1016\/j.bmc.2007.12.040"},{"key":"19_CR17_19","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/0003-2697(83)90258-0","volume":"134","author":"DA Kendall","year":"1983","unstructured":"Kendall DA, MacDonald RC (1983) Characterization of a fluorescence assay to monitor changes in the aqueous volume of lipid vesicles. Anal Biochem 134:26\u201333","journal-title":"Anal Biochem"},{"key":"19_CR18_19","doi-asserted-by":"publisher","first-page":"1161","DOI":"10.1097\/01.ASN.0000125617.19799.72","volume":"15","author":"JD Klein","year":"2004","unstructured":"Klein JD, Sands JM, Qian L, Wang X, Yang B (2004) Upregulation of urea transporter UT-A2 and water channels AQP2 and AQP3 in mice lacking urea transporter UT-B. J Am Soc Nephrol 15:1161\u20131167","journal-title":"J Am Soc Nephrol"},{"key":"19_CR19_19","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1113\/jphysiol.1990.sp018095","volume":"425","author":"DG Lang","year":"1990","unstructured":"Lang DG, Ritchie AK (1990) Tetraethyl ammonium blockade of apamin-sensitive and insensitive Ca2+activated K+ channels in a pituitary cell line. J Physiol 425:117\u2013132","journal-title":"J Physiol"},{"key":"19_CR20_19","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1073\/pnas.79.3.805","volume":"79","author":"R Latorre","year":"1982","unstructured":"Latorre R, Vergara C, Hidalgo C (1982) Reconstitution in planar lipid bilayers of a Ca2+dependent K+ channel from transverse tubule membranes isolated from rabbit skeletal muscle. Proc Natl Acad Sci U S A 79:805\u2013809","journal-title":"Proc Natl Acad Sci U S A"},{"key":"19_CR21_19","doi-asserted-by":"crossref","first-page":"C612","DOI":"10.1152\/ajpcell.2000.278.3.C612","volume":"278","author":"H Lee","year":"2000","unstructured":"Lee H, Goetzl EJ, An S (2000) Lysophosphatidic acid and sphingosine 1-phosphate stimulate en-dothelial cell wound healing. Am J Physiol Cell Physiol 278:C612\u2013618","journal-title":"Am J Physiol Cell Physiol"},{"key":"19_CR22_19","doi-asserted-by":"publisher","first-page":"4365","DOI":"10.1167\/iovs.06-0335","volume":"47","author":"MH Levin","year":"2006","unstructured":"Levin MH, Verkman AS (2006) Aquaporin-3-dependent cell migration and proliferation during corneal re-epithelialization. Invest Ophthalmol Vis Sci 47:4365\u20134372","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"19_CR23_19","doi-asserted-by":"publisher","first-page":"4296","DOI":"10.1074\/jbc.273.8.4296","volume":"273","author":"T Ma","year":"1998","unstructured":"Ma T, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS (1998) Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels. J Biol Chem 273:4296\u20134299","journal-title":"J Biol Chem"},{"key":"19_CR24_19","doi-asserted-by":"publisher","first-page":"4386","DOI":"10.1073\/pnas.080499597","volume":"97","author":"T Ma","year":"2000","unstructured":"Ma T, Song Y, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS (2000) Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels. Proc Natl Acad Sci U S A 97:4386\u20134391","journal-title":"Proc Natl Acad Sci U S A"},{"key":"19_CR25_19","first-page":"90","volume":"25","author":"B Ma","year":"2004","unstructured":"Ma B, Xiang Y, Mu SM, Li T, Yu HM, Li XJ (2004) Effects of acetazolamide and anordiol on osmotic water permeability in AQP1-cRNA injected Xenopus oocyte. Acta Pharmacol Sin 25: 90\u201397","journal-title":"Acta Pharmacol Sin"},{"key":"19_CR26_19","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/0005-2736(70)90130-6","volume":"211","author":"RI Macey","year":"1970","unstructured":"Macey RI, Farmer REL (1970) Inhibition of water and solute permeability in human red cells. Biochim Biophys Acta 211:104\u2013106","journal-title":"Biochim Biophys Acta"},{"key":"19_CR27_19","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1038\/72256","volume":"6","author":"GT Manley","year":"2000","unstructured":"Manley GT, Fujimura M, Ma T, Noshita N, Filiz F, Bollen AW, Chan P, Verkman AS (2000) Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nat Med 6:159\u2013163","journal-title":"Nat Med"},{"key":"19_CR28_19","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1002\/glia.20524","volume":"55","author":"E McCoy","year":"2007","unstructured":"McCoy E, Sontheimer H (2007) Expression and function of water channels (aquaporins) in migrating malignant astrocytes. Glia 55:1034\u20131043","journal-title":"Glia"},{"key":"19_CR29_19","doi-asserted-by":"publisher","first-page":"32446","DOI":"10.1074\/jbc.273.49.32446","volume":"273","author":"AK Meinild","year":"1998","unstructured":"Meinild AK, Klaerke DA, Zeuthen T (1998) Bidirectional water fluxes and specificity for small hydrophilic molecules in aquaporins 0\u20135. J Biol Chem 273:32446\u201332451","journal-title":"J Biol Chem"},{"key":"19_CR30_19","doi-asserted-by":"publisher","first-page":"6777","DOI":"10.1074\/jbc.275.10.6777","volume":"275","author":"KL \u00e9meth-Cahalan","year":"2000","unstructured":"N\u00e9meth-Cahalan KL, Hall JE (2000) pH and calcium regulate the water permeability of aquaporin 0. J Biol Chem 275:6777\u20136782","journal-title":"J Biol Chem"},{"key":"19_CR31_19","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1523\/JNEUROSCI.17-01-00171.1997","volume":"17","author":"S Nielsen","year":"1997","unstructured":"Nielsen S, Nagelhus EA, Amiry-Moghaddam M, Bourque C, Agre P, Ottersen OP (1997) Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain. J Neurosci 17:171\u2013180","journal-title":"J Neurosci"},{"key":"19_CR32_19","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1016\/S0014-5793(02)03581-0","volume":"531","author":"CM Niemietz","year":"2002","unstructured":"Niemietz CM, Tyerman SD (2002) New potent inhibitors of aquaporins: silver and gold compounds inhibit aquaporins of plant and human origin. FEBS Lett 531:443\u2013447","journal-title":"FEBS Lett"},{"key":"19_CR33_19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/sj.bjp.0707348","volume":"152","author":"M Oheim","year":"2007","unstructured":"Oheim M (2007) High-throughput microscopy must re-invent the microscope rather than speed up its functions. Br J Pharmacol 152:1\u20134","journal-title":"Br J Pharmacol"},{"key":"19_CR34_19","unstructured":"Papadopoulos MC, Saadoun S, Verkman AS (2007) Aquaporins and cell migration. Pflugers Arch Eur J Physiol. doi 10.1007\/s00424-007-0357-5"},{"key":"19_CR35_19","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1007\/s00232-001-0052-y","volume":"183","author":"I Perchenet","year":"2001","unstructured":"Perchenet I, Cl\u00e9ment-Chomienne O (2001) External nickel blocks human Kv1.5 channels stably expressed in CHO cells. J Membr Biol 183:51\u201360","journal-title":"J Membr Biol"},{"key":"19_CR36_19","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1126\/science.256.5055.385","volume":"256","author":"GM Preston","year":"1992","unstructured":"Preston GM, Carroll TP, Guggino WB, Agre P (1992) Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein. Science 256:385\u2013387","journal-title":"Science"},{"key":"19_CR37_19","doi-asserted-by":"publisher","first-page":"2211","DOI":"10.1073\/pnas.0610843104","volume":"104","author":"D Promeneur","year":"2007","unstructured":"Promeneur D, Liu Y, Maciel J, Agre P, King LS, Kumar N (2007) Aquaglyceroporin PbAQP during intraerythrocytic development of the malaria parasite Plasmodium berghei. Proc Natl Acad Sci U S A 104:2211\u20132216","journal-title":"Proc Natl Acad Sci U S A"},{"key":"19_CR38_19","doi-asserted-by":"publisher","first-page":"6037","DOI":"10.1073\/pnas.0511324103","volume":"103","author":"A Rojek","year":"2006","unstructured":"Rojek A, Fuchtbauer EM, Kwon TH, Frokiaer J, Nielsen S (2006) Severe urinary concentrating defect in renal collecting duct-selective AQP2 conditional-knockout mice. Proc Natl Acad Sci U S A 103:6037\u20136042","journal-title":"Proc Natl Acad Sci U S A"},{"key":"19_CR39_19","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1038\/nature03460","volume":"434","author":"S Saadoun","year":"2005","unstructured":"Saadoun S, Papadopoulos MC, Hara-Chikuma M, Verkman AS (2005) Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption. Nature 434:786\u2013792","journal-title":"Nature"},{"key":"19_CR40_19","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/j.jmb.2007.02.070","volume":"368","author":"DF Savage","year":"2007","unstructured":"Savage DF, Stroud RM (2007) Structural basis of aquaporin inhibition by mercury. J Mol Biol 368:607\u2013617","journal-title":"J Mol Biol"},{"key":"19_CR41_19","doi-asserted-by":"crossref","first-page":"6407","DOI":"10.1016\/S0021-9258(18)38133-X","volume":"266","author":"BL Smith","year":"1991","unstructured":"Smith BL, Agre P (1991) Erythrocyte Mr 28,000 transmembrane protein exists as a multisubunit oligomer similar to channel proteins. J Biol Chem 266:6407\u20136415","journal-title":"J Biol Chem"},{"key":"19_CR42_19","unstructured":"Sogaard R, Zeuthen T (2007) Test of blockers of AQP1 water permeability by a high-resolution method no effects of tetraethylammonium ions or acetazolamide. Pflugers Arch Eur J Physiol. doi 10.1007\/s00424-007-0392-2"},{"key":"19_CR43_19","doi-asserted-by":"publisher","first-page":"C426","DOI":"10.1152\/ajpcell.00298.2003","volume":"286","author":"E Solenov","year":"2004","unstructured":"Solenov E, Watanabe H, Manley GT, Verkman AS (2004) Sevenfold-reduced osmotic water permeability in primary astrocyte cultures from AQP-4-deficient mice, measured by a fluorescence quenching method. Am J Physiol Cell Physiol 286:C426\u2013C432","journal-title":"Am J Physiol Cell Physiol"},{"key":"19_CR44_19","doi-asserted-by":"publisher","first-page":"43830","DOI":"10.1074\/jbc.M207221200","volume":"277","author":"JJ Steinle","year":"2002","unstructured":"Steinle JJ, Meininger CJ, Forough R, Wu G, Wu MH, Granger HJ (2002) Eph B4 receptor signaling mediates endothelial cell migration and proliferation via the phosphatidylinositol 3-kinase pathway. J Biol Chem 277:43830\u201343835","journal-title":"J Biol Chem"},{"key":"19_CR45_19","doi-asserted-by":"publisher","first-page":"24737","DOI":"10.1074\/jbc.273.38.24737","volume":"273","author":"H Tsukaguchi","year":"1998","unstructured":"Tsukaguchi H, Shayakul C, Berger UV, Mackenzie B, Devidas S,Guggino WB, van Hoek AN, Hediger MA (1998) Molecular characterization of a broad selectivity neutral solute channel. J Biol Chem 273:24737\u201324743","journal-title":"J Biol Chem"},{"key":"19_CR46_19","first-page":"F685","volume":"277","author":"H Tsukaguchi","year":"1999","unstructured":"Tsukaguchi H, Weremowicz S, Morton CC, Hediger MA (1999) Functional and molecular characterization of the human neutral solute channel aquaporin-9. Am J Physiol 277:F685\u2013F696","journal-title":"Am J Physiol"},{"key":"19_CR47_19","doi-asserted-by":"publisher","first-page":"13131","DOI":"10.1073\/pnas.192457099","volume":"99","author":"Z Vajda","year":"2002","unstructured":"Vajda Z, Pedersen M, Fuchtbauer EM, Wertz K, Stodkilde-Jorgensen H, Sulyok E, Doczi T, Neely JD, Agre P, Frokiaer J, Nielsen S (2002) Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null transgenic mice. Proc Natl Acad Sci U S A 99:13131\u201313136","journal-title":"Proc Natl Acad Sci U S A"},{"key":"19_CR48_19","doi-asserted-by":"crossref","first-page":"18267","DOI":"10.1016\/S0021-9258(19)36953-4","volume":"267","author":"AN Hoek Van","year":"1992","unstructured":"Van Hoek AN, Verkman AS (1992) Functional reconstitution of the isolated erythrocyte water channel CHIP28. J Biol Chem 267:18267\u201318269","journal-title":"J Biol Chem"},{"key":"19_CR49_19","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/0005-2736(90)90296-Z","volume":"1030","author":"AN Hoek Van","year":"1990","unstructured":"Van Hoek AN, De Jong MD, Van Os CH (1990) Effects of dimethylsulfoxide and mercurial sulfhydryl reagents on water and solute permeability of rat kidney brush border membranes. Biochim Biophys Acta- Biomembr 1030:203\u2013210","journal-title":"Biochim Biophys Acta- Biomembr"},{"key":"19_CR50_19","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1007\/s002320001009","volume":"173","author":"AS Verkman","year":"2000","unstructured":"Verkman AS (2000) Water permeability measurement in living cells and complex tissues. J Membr Biol 173:73\u201387","journal-title":"J Membr Biol"},{"key":"19_CR51_19","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1085\/jgp.105.4.507","volume":"105","author":"F Wehner","year":"1995","unstructured":"Wehner F, Sauer H, Kinne RK (1995) Hypertonic stress increases the Na+ conductance of rat hepatocytes in primary culture. J Gen Physiol 105:507\u2013535","journal-title":"J Gen Physiol"},{"key":"19_CR52_19","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1007\/s00424-007-0383-3","volume":"456","author":"B Wu","year":"2007","unstructured":"Wu B, Altmann K, Barzel I, Krehan S, Beitz E (2007) A yeast-based phenotypic screen for aqua-porin inhibitors. Pflugers Arch 456:717\u2013720","journal-title":"Pflugers Arch"},{"key":"19_CR53_19","first-page":"36782","volume":"277","author":"B Yang","year":"2002","unstructured":"Yang B, Verkman AS (2002) Analysis of double knockout mice lacking aquaporin-1 and urea transporter UT-B. Evidence for UT-B-facilitated water transport in erythrocytes. J Biol Chem 277:36782\u201336786","journal-title":"Evidence for UT-B-facilitated water transport in erythrocytes. J Biol Chem"},{"key":"19_CR54_19","doi-asserted-by":"publisher","first-page":"6679","DOI":"10.1016\/j.febslet.2006.11.025","volume":"580","author":"B Yang","year":"2006","unstructured":"Yang B, Kim JK, Verkman AS (2006) Comparative efficacy of HgCl2with candidate aquaporin-1 inhibitors DMSO, gold, TEA+and acetazolamide. FEBS Lett 580:6679\u20136684","journal-title":"FEBS Lett"},{"key":"19_CR55_19","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1038\/46045","volume":"402","author":"M Yasui","year":"1999","unstructured":"Yasui M, Hazam A, Kwon TH, Nielsen S, Guggino WB, Agre P (1999) Rapid gating and anion permeability of an intracellular aquaporin. Nature 402:184\u2013187","journal-title":"Nature"},{"key":"19_CR56_19","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1472-6793-2-4","volume":"2","author":"A Yool","year":"2002","unstructured":"Yool A, Brokl O, Pannabecker T, Dantzler W, Stamer D (2002) TEA block of water flux in AQP1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line. BMC Physiol 2:1\u20138","journal-title":"BMC Physiol"},{"key":"19_CR57_19","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1007\/s002329900059","volume":"151","author":"GW Zamponi","year":"1996","unstructured":"Zamponi GW, Bourinet E, Snutch TP (1996) Nickel block of a family of neuronal calcium channels: subtype- and subunit-dependent action at multiple sites. J Membr Biol 151:77\u201390","journal-title":"J Membr Biol"},{"key":"19_CR58_19","doi-asserted-by":"publisher","first-page":"7436","DOI":"10.1021\/bi00148a002","volume":"31","author":"ML Zeidel","year":"1992","unstructured":"Zeidel ML, Ambudkar SV, Smith BL, Agre P (1992) Reconstitution of functional water channels in liposomes containing purified red cell CHIP28 protein. Biochemistry 31:7436\u20137440","journal-title":"Biochemistry"},{"key":"19_CR59_19","doi-asserted-by":"crossref","first-page":"F309","DOI":"10.1152\/ajprenal.00260.2001","volume":"283","author":"M Zelenina","year":"2002","unstructured":"Zelenina M, Zelenin S, Bondar AA, Brismar H, Aperia A (2002) Water permeability of aquaporin-4 is decreased by protein kinase C and dopamine. Am J Physiol Renal Physiol 283:F309\u2013F318","journal-title":"Am J Physiol Renal Physiol"},{"key":"19_CR60_19","doi-asserted-by":"publisher","first-page":"30037","DOI":"10.1074\/jbc.M302206200","volume":"278","author":"M Zelenina","year":"2003","unstructured":"Zelenina M, Bondar AA, Zelenin S, Aperia A (2003) Nickel and extracellular acidification inhibit the water permeability of human aquaporin-3 in lung epithelial cells. J Biol Chem 278:30037\u2013 30043","journal-title":"J Biol Chem"},{"key":"19_CR61_19","doi-asserted-by":"publisher","first-page":"51939","DOI":"10.1074\/jbc.M407645200","volume":"279","author":"M Zelenina","year":"2004","unstructured":"Zelenina M, Tritto S, Bondar AA, Zelenin S, Aperia A (2004) Copper inhibits the water and glyc-erol permeability of aquaporin-3. J Biol Chem 279:51939\u201351943","journal-title":"J Biol Chem"},{"key":"19_CR62_19","doi-asserted-by":"publisher","first-page":"2938","DOI":"10.1021\/bi00063a002","volume":"32","author":"R Zhang","year":"1993","unstructured":"Zhang R, van Hoek AN, Biwersi J, Verkman AS (1993) A point mutation at cysteine 189 blocks the water permeability of rat kidney water channel CHIP28k. Biochemistry 32:2938\u20132941","journal-title":"Biochemistry"}],"container-title":["Handbook of Experimental Pharmacology","Aquaporins"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-540-79885-9_19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T08:36:35Z","timestamp":1738830995000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-540-79885-9_19"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"ISBN":["9783540798842","9783540798859"],"references-count":62,"URL":"https:\/\/doi.org\/10.1007\/978-3-540-79885-9_19","relation":{},"ISSN":["0171-2004"],"issn-type":[{"value":"0171-2004","type":"print"}],"subject":[],"published":{"date-parts":[[2009]]}}}