{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T03:10:52Z","timestamp":1743045052710,"version":"3.40.3"},"publisher-location":"Berlin, Heidelberg","reference-count":60,"publisher":"Springer Berlin Heidelberg","isbn-type":[{"type":"print","value":"9783642160363"},{"type":"electronic","value":"9783642160370"}],"license":[{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2012,9,1]],"date-time":"2012-09-01T00:00:00Z","timestamp":1346457600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013]]},"DOI":"10.1007\/978-3-642-16037-0_10","type":"book-chapter","created":{"date-parts":[[2012,8,31]],"date-time":"2012-08-31T08:27:24Z","timestamp":1346401644000},"page":"145-164","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Transplantation for Hepatocellular Carcinoma: The North American Experience"],"prefix":"10.1007","author":[{"given":"Truman Mark","family":"Earl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William C.","family":"Chapman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,9,1]]},"reference":[{"key":"10_CR1","first-page":"659","volume":"117","author":"TE Starzl","year":"1963","unstructured":"Starzl TE, Marchioro TL, Vonkaulla KN, Hermann G, Brittain RS, Waddell WR (1963) Homotransplantation of the liver in humans. Surg Gynecol Obstet 117:659\u2013676","journal-title":"Surg Gynecol Obstet"},{"issue":"1","key":"10_CR2","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1007\/BF01656377","volume":"6","author":"S Iwatsuki","year":"1982","unstructured":"Iwatsuki S, Klintmalm GB, Starzl TE (1982) Total hepatectomy and liver replacement (orthotopic liver transplantation) for primary hepatic malignancy. World J Surg 6(1):81\u201385","journal-title":"World J Surg"},{"issue":"1 suppl","key":"10_CR3","doi-asserted-by":"publisher","first-page":"56S","DOI":"10.1002\/hep.1840040716","volume":"4","author":"R Pichlmayr","year":"1984","unstructured":"Pichlmayr R, Brolsch C, Wonigeit K, Neuhaus P, Siegismund S, Schmidt FW, Burdelski M (1984) Experiences with liver transplantation in Hannover. Hepatology 4(1 suppl):56S\u201360S","journal-title":"Hepatology"},{"issue":"4","key":"10_CR4","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1097\/00000658-198510000-00001","volume":"202","author":"S Iwatsuki","year":"1985","unstructured":"Iwatsuki S, Gordon RD, Shaw BW Jr, Starzl TE (1985) Role of liver transplantation in cancer therapy. Ann Surg 202(4):401\u2013407","journal-title":"Ann Surg"},{"issue":"5630","key":"10_CR5","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1136\/bmj.4.5630.535","volume":"4","author":"RY Calne","year":"1968","unstructured":"Calne RY, Williams R (1968) Liver transplantation in man. I. Observations on technique and organization in five cases. Br Med J 4(5630):535\u2013540","journal-title":"Br Med J"},{"issue":"5630","key":"10_CR6","first-page":"541","volume":"4","author":"RY Calne","year":"1968","unstructured":"Calne RY, Williams R, Dawson JL, Ansell ID, Evans DB, Flute PT, Herbertson PM, Joysey V, Keates GH, Knill-Jones RP, Mason SA, Millard PR, Pena JR, Pentlow BD, Salaman JR, Sells RA, Cullum PA (1968) Liver transplantation in man. II. A report of two orthotopic liver transplants in adult recipients. Br Med J 4(5630):541\u2013546","journal-title":"Br Med J"},{"issue":"4","key":"10_CR7","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1097\/00000658-198804000-00002","volume":"207","author":"JG O\u2019Grady","year":"1988","unstructured":"O\u2019Grady JG, Polson RJ, Rolles K, Calne RY, Williams R (1988) Liver transplantation for malignant disease. Results in 93 consecutive patients. Ann Surg 207(4):373\u2013379","journal-title":"Ann Surg"},{"issue":"4","key":"10_CR8","first-page":"726","volume":"110","author":"I Penn","year":"1991","unstructured":"Penn I (1991) Hepatic transplantation for primary and metastatic cancers of the liver. Surgery 110(4):726\u2013734 (discussion 734\u2013725)","journal-title":"Surgery"},{"issue":"10","key":"10_CR9","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1001\/archsurg.1990.01410220045007","volume":"125","author":"KM Olthoff","year":"1990","unstructured":"Olthoff KM, Millis JM, Rosove MH, Goldstein LI, Ramming KP, Busuttil RW (1990) Is liver transplantation justified for the treatment of hepatic malignancies. Arch Surg 125(10):1261\u20131266 (discussion 1266\u20131268)","journal-title":"Arch Surg"},{"issue":"11","key":"10_CR10","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1056\/NEJM199603143341104","volume":"334","author":"V Mazzaferro","year":"1996","unstructured":"Mazzaferro V, Regalia E, Doci R, Andreola S, Pulvirenti A, Bozzetti F, Montalto F, Ammatuna M, Morabito A, Gennari L (1996) Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 334(11):693\u2013699","journal-title":"N Engl J Med"},{"issue":"4","key":"10_CR11","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1097\/00000658-199810000-00005","volume":"228","author":"GB Klintmalm","year":"1998","unstructured":"Klintmalm GB (1998) Liver transplantation for hepatocellular carcinoma: a registry report of the impact of tumor characteristics on outcome. Ann Surg 228(4):479\u2013490","journal-title":"Ann Surg"},{"issue":"3","key":"10_CR12","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1097\/00000658-199109000-00005","volume":"214","author":"S Iwatsuki","year":"1991","unstructured":"Iwatsuki S, Starzl TE, Sheahan DG, Yokoyama I, Demetris AJ, Todo S, Tzakis AG, Van Thiel DH, Carr B, Selby R et al (1991) Hepatic resection versus transplantation for hepatocellular carcinoma. Ann Surg 214(3):221\u2013228 (discussion 228\u2013229)","journal-title":"Ann Surg"},{"issue":"2","key":"10_CR13","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/bjs.1800820239","volume":"82","author":"KC Tan","year":"1995","unstructured":"Tan KC, Rela M, Ryder SD, Rizzi PM, Karani J, Portmann B, Heaton ND, Howard ER, Williams R (1995) Experience of orthotopic liver transplantation and hepatic resection for hepatocellular carcinoma of less than 8\u00a0cm in patients with cirrhosis. Br J Surg 82(2):253\u2013256","journal-title":"Br J Surg"},{"issue":"2","key":"10_CR14","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1097\/00000658-199308000-00005","volume":"218","author":"H Bismuth","year":"1993","unstructured":"Bismuth H, Chiche L, Adam R, Castaing D, Diamond T, Dennison A (1993) Liver resection versus transplantation for hepatocellular carcinoma in cirrhotic patients. Ann Surg 218(2):145\u2013151","journal-title":"Ann Surg"},{"issue":"7","key":"10_CR15","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1002\/lt.20140","volume":"10","author":"K Shetty","year":"2004","unstructured":"Shetty K, Timmins K, Brensinger C, Furth EE, Rattan S, Sun W, Rosen M, Soulen M, Shaked A, Reddy KR, Olthoff KM (2004) Liver transplantation for hepatocellular carcinoma validation of present selection criteria in predicting outcome. Liver Transpl 10(7):911\u2013918","journal-title":"Liver Transpl"},{"issue":"6","key":"10_CR16","doi-asserted-by":"publisher","first-page":"1572","DOI":"10.1002\/hep.510270616","volume":"27","author":"JM Llovet","year":"1998","unstructured":"Llovet JM, Bruix J, Fuster J, Castells A, Garcia-Valdecasas JC, Grande L, Franca A, Bru C, Navasa M, Ayuso MC, Sole M, Real MI, Vilana R, Rimola A, Visa J, Rodes J (1998) Liver transplantation for small hepatocellular carcinoma: the tumor-node-metastasis classification does not have prognostic power. Hepatology 27(6):1572\u20131577","journal-title":"Hepatology"},{"issue":"23","key":"10_CR17","doi-asserted-by":"publisher","first-page":"4329","DOI":"10.1200\/JCO.2003.11.137","volume":"21","author":"HY Yoo","year":"2003","unstructured":"Yoo HY, Patt CH, Geschwind JF, Thuluvath PJ (2003) The outcome of liver transplantation in patients with hepatocellular carcinoma in the United States between 1988 and 2001: 5-year survival has improved significantly with time. J Clin Oncol 21(23):4329\u20134335","journal-title":"J Clin Oncol"},{"issue":"5 suppl 1","key":"10_CR18","doi-asserted-by":"publisher","first-page":"S261","DOI":"10.1053\/j.gastro.2004.09.040","volume":"127","author":"RH Wiesner","year":"2004","unstructured":"Wiesner RH, Freeman RB, Mulligan DC (2004) Liver transplantation for hepatocellular cancer: the impact of the MELD allocation policy. Gastroenterology 127(5 suppl 1):S261\u2013S267","journal-title":"Gastroenterology"},{"issue":"10","key":"10_CR19","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1053\/jlts.2002.34923","volume":"8","author":"FY Yao","year":"2002","unstructured":"Yao FY, Bass NM, Nikolai B, Davern TJ, Kerlan R, Wu V, Ascher NL, Roberts JP (2002) Liver transplantation for hepatocellular carcinoma: analysis of survival according to the intention-to-treat principle and dropout from the waiting list. Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc 8(10):873\u2013883","journal-title":"Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc"},{"issue":"6","key":"10_CR20","doi-asserted-by":"publisher","first-page":"1434","DOI":"10.1002\/hep.510300629","volume":"30","author":"JM Llovet","year":"1999","unstructured":"Llovet JM, Fuster J, Bruix J (1999) Intention-to-treat analysis of surgical treatment for early hepatocellular carcinoma: resection versus transplantation. Hepatology 30(6):1434\u20131440","journal-title":"Hepatology"},{"issue":"5","key":"10_CR21","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1053\/jlts.2000.9744","volume":"6","author":"RB Freeman Jr","year":"2000","unstructured":"Freeman RB Jr, Edwards EB (2000) Liver transplant waiting time does not correlate with waiting list mortality: implications for liver allocation policy. Liver Transpl 6(5):543\u2013552","journal-title":"Liver Transpl"},{"issue":"202","key":"10_CR22","first-page":"56650","volume":"64","author":"Organ procurement and transplantation network. Health resources and services administration, HHS. Final rule","year":"1999","unstructured":"Organ procurement and transplantation network. Health resources and services administration, HHS. Final rule (1999). Fed Regist 64(202):56650\u201356661","journal-title":"Fed Regist"},{"issue":"4","key":"10_CR23","doi-asserted-by":"publisher","first-page":"864","DOI":"10.1053\/he.2000.5852","volume":"31","author":"M Malinchoc","year":"2000","unstructured":"Malinchoc M, Kamath PS, Gordon FD, Peine CJ, Rank J, ter Borg PC (2000) A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts. Hepatology 31(4):864\u2013871","journal-title":"Hepatology"},{"issue":"7","key":"10_CR24","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1053\/jlts.2001.25879","volume":"7","author":"RH Wiesner","year":"2001","unstructured":"Wiesner RH, McDiarmid SV, Kamath PS, Edwards EB, Malinchoc M, Kremers WK, Krom RA, Kim WR (2001) MELD and PELD: application of survival models to liver allocation. Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc 7(7):567\u2013580","journal-title":"Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc"},{"issue":"1","key":"10_CR25","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1053\/gast.2003.50016","volume":"124","author":"R Wiesner","year":"2003","unstructured":"Wiesner R, Edwards E, Freeman R, Harper A, Kim R, Kamath P, Kremers W, Lake J, Howard T, Merion RM, Wolfe RA, Krom R (2003) Model for end-stage liver disease (MELD) and allocation of donor livers. Gastroenterology 124(1):91\u201396","journal-title":"Gastroenterology"},{"issue":"10 suppl 2","key":"10_CR26","doi-asserted-by":"publisher","first-page":"A6","DOI":"10.1002\/lt.20247","volume":"10","author":"KM Olthoff","year":"2004","unstructured":"Olthoff KM, Brown RS Jr, Delmonico FL, Freeman RB, McDiarmid SV, Merion RM, Millis JM, Roberts JP, Shaked A, Wiesner RH, Lucey MR (2004) Summary report of a national conference: evolving concepts in liver allocation in the MELD and PELD era, December 8, 2003, Washington, DC, USA. Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc 10(10 suppl 2):A6\u2013A22","journal-title":"Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc"},{"issue":"1","key":"10_CR27","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1002\/lt.20012","volume":"10","author":"P Sharma","year":"2004","unstructured":"Sharma P, Balan V, Hernandez JL, Harper AM, Edwards EB, Rodriguez-Luna H, Byrne T, Vargas HE, Mulligan D, Rakela J, Wiesner RH (2004) Liver transplantation for hepatocellular carcinoma: the MELD impact. Liver Transplant: Off Publ Am Assoc Study of Liver Dis Int Liver Transplant Soc 10(1):36\u201341","journal-title":"Liver Transplant: Off Publ Am Assoc Study of Liver Dis Int Liver Transplant Soc"},{"issue":"1","key":"10_CR28","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1002\/lt.20024","volume":"10","author":"RB Freeman","year":"2004","unstructured":"Freeman RB, Wiesner RH, Edwards E, Harper A, Merion R, Wolfe R (2004) Results of the first year of the new liver allocation plan. Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc 10(1):7\u201315","journal-title":"Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc"},{"issue":"8","key":"10_CR29","doi-asserted-by":"publisher","first-page":"1957","DOI":"10.1111\/j.1600-6143.2006.01411.x","volume":"6","author":"P Sharma","year":"2006","unstructured":"Sharma P, Harper AM, Hernandez JL, Heffron T, Mulligan DC, Wiesner RH, Balan V (2006) Reduced priority MELD score for hepatocellular carcinoma does not adversely impact candidate survival awaiting liver transplantation. Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg 6(8):1957\u20131962","journal-title":"Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg"},{"issue":"3","key":"10_CR30","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1097\/SLA.0b013e318148c704","volume":"246","author":"JP Duffy","year":"2007","unstructured":"Duffy JP, Vardanian A, Benjamin E, Watson M, Farmer DG, Ghobrial RM, Lipshutz G, Yersiz H, Lu DS, Lassman C, Tong MJ, Hiatt JR, Busuttil RW (2007) Liver transplantation criteria for hepatocellular carcinoma should be expanded: a 22-year experience with 467\u00a0patients at UCLA. Ann Surg 246(3):502\u2013509 (discussion 509\u2013511)","journal-title":"Ann Surg"},{"issue":"5","key":"10_CR31","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1007\/s00534-009-0163-x","volume":"17","author":"N Onaca","year":"2010","unstructured":"Onaca N, Klintmalm GB (2010) Liver transplantation for hepatocellular carcinoma: the Baylor experience. J Hepatobiliary Pancreat Sci 17(5):559\u2013566","journal-title":"J Hepatobiliary Pancreat Sci"},{"issue":"5","key":"10_CR32","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1053\/jhep.2001.23311","volume":"33","author":"FP Sarasin","year":"2001","unstructured":"Sarasin FP, Majno PE, Llovet JM, Bruix J, Mentha G, Hadengue A (2001) Living donor liver transplantation for early hepatocellular carcinoma: a life-expectancy and cost-effectiveness perspective. Hepatology 33(5):1073\u20131079","journal-title":"Hepatology"},{"issue":"8","key":"10_CR33","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1002\/lt.21778","volume":"15","author":"SJ Pelletier","year":"2009","unstructured":"Pelletier SJ, Fu S, Thyagarajan V, Romero-Marrero C, Batheja MJ, Punch JD, Magee JC, Lok AS, Fontana RJ, Marrero JA (2009) An intention-to-treat analysis of liver transplantation for hepatocellular carcinoma using organ procurement transplant network data. Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc 15(8):859\u2013868","journal-title":"Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc"},{"issue":"3","key":"10_CR34","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1002\/lt.20099","volume":"10","author":"YK Maddala","year":"2004","unstructured":"Maddala YK, Stadheim L, Andrews JC, Burgart LJ, Rosen CB, Kremers WK, Gores G (2004) Drop-out rates of patients with hepatocellular cancer listed for liver transplantation: outcome with chemoembolization. Liver Transplant: Off Publ Am Assoc Study of Liver Dis Int Liver Transplant Soc 10(3):449\u2013455","journal-title":"Liver Transplant: Off Publ Am Assoc Study of Liver Dis Int Liver Transplant Soc"},{"issue":"5","key":"10_CR35","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1097\/01.sla.0000143301.56154.95","volume":"240","author":"V Mazzaferro","year":"2004","unstructured":"Mazzaferro V, Battiston C, Perrone S, Pulvirenti A, Regalia E, Romito R, Sarli D, Schiavo M, Garbagnati F, Marchiano A, Spreafico C, Camerini T, Mariani L, Miceli R, Andreola S (2004) Radiofrequency ablation of small hepatocellular carcinoma in cirrhotic patients awaiting liver transplantation: a prospective study. Ann Surg 240(5):900\u2013909","journal-title":"Ann Surg"},{"issue":"9319","key":"10_CR36","doi-asserted-by":"publisher","first-page":"1734","DOI":"10.1016\/S0140-6736(02)08649-X","volume":"359","author":"JM Llovet","year":"2002","unstructured":"Llovet JM, Real MI, Montana X, Planas R, Coll S, Aponte J, Ayuso C, Sala M, Muchart J, Sola R, Rodes J, Bruix J (2002) Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial. Lancet 359(9319):1734\u20131739","journal-title":"Lancet"},{"issue":"2","key":"10_CR37","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1053\/jhep.2003.50047","volume":"37","author":"JM Llovet","year":"2003","unstructured":"Llovet JM, Bruix J (2003) Systematic review of randomized trials for unresectable hepatocellular carcinoma: chemoembolization improves survival. Hepatology 37(2):429\u2013442","journal-title":"Hepatology"},{"issue":"5","key":"10_CR38","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.1053\/jhep.2002.33156","volume":"35","author":"CM Lo","year":"2002","unstructured":"Lo CM, Ngan H, Tso WK, Liu CL, Lam CM, Poon RT, Fan ST, Wong J (2002) Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma. Hepatology 35(5):1164\u20131171","journal-title":"Hepatology"},{"issue":"4 pt 1","key":"10_CR39","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1111\/j.1600-6143.2005.00750.x","volume":"5","author":"FY Yao","year":"2005","unstructured":"Yao FY, Kinkhabwala M, LaBerge JM, Bass NM, Brown R Jr, Kerlan R, Venook A, Ascher NL, Emond JC, Roberts JP (2005) The impact of pre-operative loco-regional therapy on outcome after liver transplantation for hepatocellular carcinoma. Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg 5(4 pt 1):795\u2013804","journal-title":"Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg"},{"issue":"4","key":"10_CR40","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/j.jamcollsurg.2006.06.016","volume":"203","author":"A Bharat","year":"2006","unstructured":"Bharat A, Brown DB, Crippin JS, Gould JE, Lowell JA, Shenoy S, Desai NM, Chapman WC (2006) Pre-liver transplantation locoregional adjuvant therapy for hepatocellular carcinoma as a strategy to improve longterm survival. J Am Coll Surg 203(4):411\u2013420","journal-title":"J Am Coll Surg"},{"issue":"6","key":"10_CR41","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1097\/01.sla.0000098621.74851.65","volume":"238","author":"J Belghiti","year":"2003","unstructured":"Belghiti J, Cortes A, Abdalla EK, Regimbeau JM, Prakash K, Durand F, Sommacale D, Dondero F, Lesurtel M, Sauvanet A, Farges O, Kianmanesh R (2003) Resection prior to liver transplantation for hepatocellular carcinoma. Ann Surg 238(6):885\u2013892 (discussion 892\u2013883)","journal-title":"Ann Surg"},{"issue":"4","key":"10_CR42","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1097\/01.sla.0000090449.87109.44","volume":"238","author":"R Adam","year":"2003","unstructured":"Adam R, Azoulay D, Castaing D, Eshkenazy R, Pascal G, Hashizume K, Samuel D, Bismuth H (2003) Liver resection as a bridge to transplantation for hepatocellular carcinoma on cirrhosis: a reasonable strategy. Ann Surg 238(4):508\u2013518 (discussion 518\u2013509)","journal-title":"Ann Surg"},{"issue":"3","key":"10_CR43","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1111\/j.1600-6143.2009.02984.x","volume":"10","author":"A Cucchetti","year":"2010","unstructured":"Cucchetti A, Vitale A, Gaudio MD, Ravaioli M, Ercolani G, Cescon M, Zanello M, Morelli MC, Cillo U, Grazi GL, Pinna AD (2010) Harm and benefits of primary liver resection and salvage transplantation for hepatocellular carcinoma. Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg 10(3):619\u2013627","journal-title":"Am J Transplant: Off J Am Soc Transplant Am Soc Transplant Surg"},{"issue":"4","key":"10_CR44","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1097\/00000658-200204000-00012","volume":"235","author":"S Roayaie","year":"2002","unstructured":"Roayaie S, Frischer JS, Emre SH, Fishbein TM, Sheiner PA, Sung M, Miller CM, Schwartz ME (2002) Long-term results with multimodal adjuvant therapy and liver transplantation for the treatment of hepatocellular carcinomas larger than 5\u00a0cm. Ann Surg 235(4):533\u2013539","journal-title":"Ann Surg"},{"issue":"10","key":"10_CR45","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1002\/lt.20237","volume":"10","author":"NM Kneteman","year":"2004","unstructured":"Kneteman NM, Oberholzer J, Saghier MA, Meeberg GA, Blitz M, Ma MM, Wong WW, Gutfreund K, Mason AL, Jewell LD, Shapiro AM, Bain VG, Bigam DL (2004) Sirolimus-based immunosuppression for liver transplantation in the presence of extended criteria for hepatocellular carcinoma. Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc 10(10):1301\u20131311","journal-title":"Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc"},{"issue":"3","key":"10_CR46","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1002\/lt.21095","volume":"13","author":"N Onaca","year":"2007","unstructured":"Onaca N, Davis GL, Goldstein RM, Jennings LW, Klintmalm GB (2007) Expanded criteria for liver transplantation in patients with hepatocellular carcinoma: a report from the International Registry of Hepatic Tumors in Liver Transplantation. Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc 13(3):391\u2013399","journal-title":"Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc"},{"issue":"6","key":"10_CR47","doi-asserted-by":"publisher","first-page":"1394","DOI":"10.1053\/jhep.2001.24563","volume":"33","author":"FY Yao","year":"2001","unstructured":"Yao FY, Ferrell L, Bass NM, Watson JJ, Bacchetti P, Venook A, Ascher NL, Roberts JP (2001) Liver transplantation for hepatocellular carcinoma: expansion of the tumor size limits does not adversely impact survival. Hepatology 33(6):1394\u20131403","journal-title":"Hepatology"},{"issue":"6","key":"10_CR48","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1097\/00000658-199712000-00006","volume":"226","author":"PE Majno","year":"1997","unstructured":"Majno PE, Adam R, Bismuth H, Castaing D, Ariche A, Krissat J, Perrin H, Azoulay D (1997) Influence of preoperative transarterial lipiodol chemoembolization on resection and transplantation for hepatocellular carcinoma in patients with cirrhosis. Ann Surg 226(6):688\u2013701 (discussion 701\u2013683)","journal-title":"Ann Surg"},{"issue":"4","key":"10_CR49","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1097\/SLA.0b013e31818a07d4","volume":"248","author":"WC Chapman","year":"2008","unstructured":"Chapman WC, Majella Doyle MB, Stuart JE, Vachharajani N, Crippin JS, Anderson CD, Lowell JA, Shenoy S, Darcy MD, Brown DB (2008) Outcomes of neoadjuvant transarterial chemoembolization to downstage hepatocellular carcinoma before liver transplantation. Ann Surg 248(4):617\u2013625","journal-title":"Ann Surg"},{"issue":"3","key":"10_CR50","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1002\/hep.22412","volume":"48","author":"FY Yao","year":"2008","unstructured":"Yao FY, Kerlan RK Jr, Hirose R, Davern TJ 3rd, Bass NM, Feng S, Peters M, Terrault N, Freise CE, Ascher NL, Roberts JP (2008) Excellent outcome following down-staging of hepatocellular carcinoma prior to liver transplantation: an intention-to-treat analysis. Hepatology 48(3):819\u2013827","journal-title":"Hepatology"},{"issue":"5","key":"10_CR51","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1097\/00007890-200109150-00021","volume":"72","author":"SJ Cheng","year":"2001","unstructured":"Cheng SJ, Pratt DS, Freeman RB Jr, Kaplan MM, Wong JB (2001) Living-donor versus cadaveric liver transplantation for non-resectable small hepatocellular carcinoma and compensated cirrhosis: a decision analysis. Transplantation 72(5):861\u2013868","journal-title":"Transplantation"},{"issue":"5 suppl 1","key":"10_CR52","doi-asserted-by":"publisher","first-page":"S277","DOI":"10.1053\/j.gastro.2004.09.042","volume":"127","author":"L Kulik","year":"2004","unstructured":"Kulik L, Abecassis M (2004) Living donor liver transplantation for hepatocellular carcinoma. Gastroenterology 127(5 suppl 1):S277\u2013S282","journal-title":"Gastroenterology"},{"doi-asserted-by":"crossref","unstructured":"Berg CL, Merion RM, Shearon TH, Olthoff KM, Brown RS Jr, Baker TB, Everson GT, Hong JC, Terrault N, Hayashi PH, Fisher RA, Everhart JE (2011) Liver transplant recipient survival benefit with living donation in the MELD allocation era. Hepatology","key":"10_CR53","DOI":"10.1002\/hep.24494"},{"issue":"5","key":"10_CR54","doi-asserted-by":"publisher","first-page":"857","DOI":"10.1097\/SLA.0b013e3181896278","volume":"248","author":"M Vivarelli","year":"2008","unstructured":"Vivarelli M, Cucchetti A, La Barba G, Ravaioli M, Del Gaudio M, Lauro A, Grazi GL, Pinna AD (2008) Liver transplantation for hepatocellular carcinoma under calcineurin inhibitors: reassessment of risk factors for tumor recurrence. Ann Surg 248(5):857\u2013862","journal-title":"Ann Surg"},{"issue":"2","key":"10_CR55","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1038\/nm0202-128","volume":"8","author":"M Guba","year":"2002","unstructured":"Guba M, von Breitenbuch P, Steinbauer M, Koehl G, Flegel S, Hornung M, Bruns CJ, Zuelke C, Farkas S, Anthuber M, Jauch KW, Geissler EK (2002) Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor. Nat Med 8(2):128\u2013135","journal-title":"Nat Med"},{"issue":"10","key":"10_CR56","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.3748\/wjg.v11.i10.1420","volume":"11","author":"G Schumacher","year":"2005","unstructured":"Schumacher G, Oidtmann M, Rueggeberg A, Jacob D, Jonas S, Langrehr JM, Neuhaus R, Bahra M, Neuhaus P (2005) Sirolimus inhibits growth of human hepatoma cells alone or combined with tacrolimus, while tacrolimus promotes cell growth. World J Gastroenterol: WJG 11(10):1420\u20131425","journal-title":"World J Gastroenterol: WJG"},{"issue":"16","key":"10_CR57","doi-asserted-by":"publisher","first-page":"5124","DOI":"10.1158\/1078-0432.CCR-07-4774","volume":"14","author":"Z Wang","year":"2008","unstructured":"Wang Z, Zhou J, Fan J, Qiu SJ, Yu Y, Huang XW, Tang ZY (2008) Effect of rapamycin alone and in combination with sorafenib in an orthotopic model of human hepatocellular carcinoma. Clin Cancer Res: Off J Am Assoc Cancer Res 14(16):5124\u20135130","journal-title":"Clin Cancer Res: Off J Am Assoc Cancer Res"},{"issue":"9","key":"10_CR58","doi-asserted-by":"publisher","first-page":"1162","DOI":"10.1097\/01.tp.0000262607.95372.e0","volume":"83","author":"C Toso","year":"2007","unstructured":"Toso C, Meeberg GA, Bigam DL, Oberholzer J, Shapiro AM, Gutfreund K, Ma MM, Mason AL, Wong WW, Bain VG, Kneteman NM (2007) De novo sirolimus-based immunosuppression after liver transplantation for hepatocellular carcinoma: long-term outcomes and side effects. Transplantation 83(9):1162\u20131168","journal-title":"Transplantation"},{"issue":"5","key":"10_CR59","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1053\/jlts.2003.50079","volume":"9","author":"JC Dunkelberg","year":"2003","unstructured":"Dunkelberg JC, Trotter JF, Wachs M, Bak T, Kugelmas M, Steinberg T, Everson GT, Kam I (2003) Sirolimus as primary immunosuppression in liver transplantation is not associated with hepatic artery or wound complications. Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc 9(5):463\u2013468","journal-title":"Liver Transplant: Off Publ Am Assoc Study Liver Dis Int Liver Transplant Soc"},{"issue":"4","key":"10_CR60","doi-asserted-by":"publisher","first-page":"1237","DOI":"10.1002\/hep.23437","volume":"51","author":"C Toso","year":"2010","unstructured":"Toso C, Merani S, Bigam DL, Shapiro AM, Kneteman NM (2010) Sirolimus-based immunosuppression is associated with increased survival after liver transplantation for hepatocellular carcinoma. Hepatology 51(4):1237\u20131243","journal-title":"Hepatology"}],"container-title":["Recent Results in Cancer Research","Multidisciplinary Treatment of Hepatocellular Carcinoma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-642-16037-0_10","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T01:04:42Z","timestamp":1675213482000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-642-16037-0_10"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,1]]},"ISBN":["9783642160363","9783642160370"],"references-count":60,"URL":"https:\/\/doi.org\/10.1007\/978-3-642-16037-0_10","relation":{},"ISSN":["0080-0015"],"issn-type":[{"type":"print","value":"0080-0015"}],"subject":[],"published":{"date-parts":[[2012,9,1]]},"assertion":[{"value":"1 September 2012","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}