{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T22:19:38Z","timestamp":1791065978999,"version":"4.1.0"},"publisher-location":"Berlin, Heidelberg","reference-count":28,"publisher":"Springer Berlin Heidelberg","isbn-type":[{"value":"9783642645600","type":"print"},{"value":"9783642608018","type":"electronic"}],"license":[{"start":{"date-parts":[[1997,1,1]],"date-time":"1997-01-01T00:00:00Z","timestamp":852076800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1997]]},"DOI":"10.1007\/978-3-642-60801-8_7","type":"book-chapter","created":{"date-parts":[[2011,9,10]],"date-time":"2011-09-10T16:29:58Z","timestamp":1315672198000},"page":"73-80","source":"Crossref","is-referenced-by-count":9,"title":["Murine and Human 3\u2032 IgH Regulatory Sequences"],"prefix":"10.1007","author":[{"given":"B. K.","family":"Birshtein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Saleque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. S.","family":"Michaelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. D.","family":"Little","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"7_CR1","first-page":"315","volume-title":"Fundamental Immunology","author":"EE Max","year":"1993","unstructured":"Max EE (1993) Immunoglobulins: Molecular Genetics. ImPaul WE (ed) Fundamental Immunology. Raven Press, N. Y., pp315\u2013383"},{"key":"7_CR2","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1038\/344165a0","volume":"344","author":"S Pettersson","year":"1990","unstructured":"Pettersson S, Cook GP, Br\u00fcggemann M, Williams GT and Neuberger MS (1990) A second B cell-specific enhancer 3\u2032 of the immunoglobulin heavy-chain locus. Nature 344:165\u2013168","journal-title":"Nature"},{"key":"7_CR3","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1093\/nar\/19.4.933","volume":"19","author":"R Lieberson","year":"1991","unstructured":"Lieberson R, Giannini SL, Birshtein BK and Eckhardt LA (1991) An enhancer at the 3\u2032 end of the mouse immunoglobulin heavy chain locus. Nucl Acids Res 19:933\u2013937","journal-title":"Nucl Acids Res"},{"key":"7_CR4","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1128\/MCB.13.3.1547","volume":"13","author":"P Matthias","year":"1993","unstructured":"Matthias P and Baltimore D (1993) The immunoglobulin heavy chain locus contains another B-cell specific 3\u2032 enhancer close to the a constant region. Mol Cell Biol 13:1547\u20131553","journal-title":"Mol Cell Biol"},{"key":"7_CR5","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1093\/nar\/23.6.975","volume":"23","author":"JS Michaelson","year":"1995","unstructured":"Michaelson JS, Giannini SL and Birshtein BK (1995) Identification of 3\u2032\u03b1-hs4, a novel Ig heavy chain enhancer element regulated at multiple stages of B cell differentiation. Nucl Acids Res 23:975\u2013981","journal-title":"Nucl Acids Res"},{"key":"7_CR6","doi-asserted-by":"publisher","first-page":"2212","DOI":"10.1101\/gad.8.18.2212","volume":"8","author":"L Madisen","year":"1994","unstructured":"Madisen L and Groudine M (1994) Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt\u2019s lymphoma cells. Genes Dev 8:2212\u20132226","journal-title":"Genes Dev"},{"key":"7_CR7","doi-asserted-by":"crossref","first-page":"1772","DOI":"10.4049\/jimmunol.150.5.1772","volume":"150","author":"SL Giannini","year":"1993","unstructured":"Giannini SL, Singh M, Calvo C-F, Ding G and Birshtein BK (1993) DNA regions flanking the mouse Ig 3\u2032\u03b1 enhancer are differentially methylated and DNAse I hypersensitive during B cell differentiation. J Immunol 150:1772\u20131780","journal-title":"J Immunol"},{"key":"7_CR8","volume-title":"Dyad symmetry within the 3\u2032 IgH regulatory region includes two virtually identical enhancers (C\u03b13\u2032E and hs3)","author":"S Saleque","year":"1997","unstructured":"Saleque S, Singh M, Little RD, Giannini SL, Michaelson JS and Birshtein BK (1997) Dyad symmetry within the 3\u2032 IgH regulatory region includes two virtually identical enhancers (C\u03b13\u2032E and hs3). J Immunol, Accepted in principle"},{"key":"7_CR9","doi-asserted-by":"crossref","first-page":"2828","DOI":"10.4049\/jimmunol.156.8.2828","volume":"156","author":"JS Michaelson","year":"1996","unstructured":"Michaelson JS, Singh M, Snapper CM, Sha WC, Baltimore D and Birshtein BK (1996) Regulation of 3\u2032 IgH enhancers by a common set of factors, including \u03baB binding proteins. J Immunol 156:2828\u20132839","journal-title":"J Immunol"},{"key":"7_CR10","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1016\/0092-8674(94)90079-5","volume":"79","author":"P Urb\u00e1nek","year":"1994","unstructured":"Urb\u00e1nek P, Wang Z-Q, Fetka I, Wagner EF and Busslinger M (1994) Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5\/BSAP. Cell 79:901\u2013912","journal-title":"Cell"},{"key":"7_CR11","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.4049\/jimmunol.156.7.2349","volume":"156","author":"JS Michaelson","year":"1996","unstructured":"Michaelson JS, Singh M and Birshtein BK (1996) B cell lineage-specific activator protein (BSAP): a player at multiple stages of B cell development. J Immunol 156:2349\u20132351","journal-title":"J Immunol"},{"key":"7_CR12","doi-asserted-by":"publisher","first-page":"1499","DOI":"10.1002\/eji.1830210625","volume":"21","author":"P Dariavach","year":"1991","unstructured":"Dariavach P, Williams GT, Campbell K, Pettersson S and Neuberger MS (1991) The mouse IgH 3\u2032-enhancer. Eur J Immunol 21:1499\u20131504","journal-title":"Eur J Immunol"},{"key":"7_CR13","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.4049\/jimmunol.146.4.1353","volume":"146","author":"C-F Calvo","year":"1991","unstructured":"Calvo C-F, Giannini SL, Martinez N and Birshtein BK (1991) DNA sequences 3\u2032 of the IgH chain cluster rearrange in mouse B cell lines. J Immunol 146:1353\u20131360","journal-title":"J Immunol"},{"key":"7_CR14","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1038\/ng0996-15","volume":"14","author":"C Chaveau","year":"1996","unstructured":"Chaveau C and Cogn\u00e9 M (1996) Palindromic structure of the IgH 3\u2032 locus control region. Nature Genet 14:15\u201316","journal-title":"Nature Genet"},{"key":"7_CR15","doi-asserted-by":"publisher","first-page":"4401","DOI":"10.1093\/nar\/20.17.4401","volume":"20","author":"PA Grant","year":"1992","unstructured":"Grant PA, Arulampalam V, \u00c4hrlund-Richter L and Pettersson S (1992) Identification of etslike lymphoid specific elements within the immunoglobulin heavy chain 3\u2032 enhancer. Nucl Acids Res 20:4401\u20134408","journal-title":"Nucl Acids Res"},{"key":"7_CR16","doi-asserted-by":"crossref","first-page":"730","DOI":"10.4049\/jimmunol.153.2.730","volume":"153","author":"MF Neurath","year":"1994","unstructured":"Neurath MF, Strober W and Wakatsuki Y (1994) The murine Ig 3\u2032\u03b1 enhancer is a target site with repressor function for the B cell lineage-specific transcription factor BSAP (NF-HB, S\u03b1 -BP). J Immunol 153:730\u2013742","journal-title":"J Immunol"},{"key":"7_CR17","doi-asserted-by":"crossref","first-page":"3611","DOI":"10.1128\/MCB.13.6.3611","volume":"13","author":"M Singh","year":"1993","unstructured":"Singh M and Birshtein BK (1993) NF-HB (BSAP) is a repressor of the murine immunoglobulin 3\u2032\u03b1 enhancer at early stages of B-cell differentiation. Mol Cell Biol 13:3611\u20133622","journal-title":"Mol Cell Biol"},{"key":"7_CR18","doi-asserted-by":"publisher","first-page":"1671","DOI":"10.1002\/eji.1830240732","volume":"24","author":"M Arulampalam","year":"1994","unstructured":"Arulampalam M, Grant PA, Samuelsson A, Lendahl U and Pettersson S (1994) Lipopolysaccharide-dependent transactivation of the temporally regulated immunoglobulin heavy chain 3\u2032 enhancer. Eur J Immunol 24:1671\u20131677","journal-title":"Eur J Immunol"},{"key":"7_CR19","doi-asserted-by":"publisher","first-page":"4392","DOI":"10.1073\/pnas.93.9.4392","volume":"93","author":"M Singh","year":"1996","unstructured":"Singh M and Birshtein BK (1996) Concerted repression of an immunoglobulin heavy chain 3\u2032\u03b1 enhancer, 3\u2032\u03b1 E(hsl,2). Proc Natl Acad Sci USA 93:4392\u20134397","journal-title":"Proc Natl Acad Sci USA"},{"key":"7_CR20","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1128\/MCB.6.6.1903","volume":"6","author":"PD Gregor","year":"1986","unstructured":"Gregor PD and Morrison SL (1986) Myeloma mutant with a novel 3\u2032 flanking region: loss of normal sequence and insertion of repetitive elements leads to decreased transcription but normal processing of the alpha heavy-chain gene products. Mol Cell Biol 6:1903\u20131916","journal-title":"Mol Cell Biol"},{"key":"7_CR21","doi-asserted-by":"crossref","first-page":"6229","DOI":"10.1002\/j.1460-2075.1995.tb00313.x","volume":"14","author":"R Lieberson","year":"1995","unstructured":"Lieberson R, Ong J, Shi X and Eckhardt LA (1995) Transcription of an immunoglobulin \u03b32a gene ceases upon deletion of an enhancer region over 70 kilobases away. EMBO J 14:6229\u20136238","journal-title":"EMBO J"},{"key":"7_CR22","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1016\/0092-8674(94)90057-4","volume":"77","author":"M Cogn\u00e9","year":"1994","unstructured":"Cogn\u00e9 M, Lansford R, Bottaro A, Zhang J, Gorman J, Young F, Cheng H-L and Alt FW (1994) A class switch control region at the 3\u2032 end of the immunoglobulin heavy chain locus. Cell 77:737\u2013747","journal-title":"Cell"},{"key":"7_CR23","doi-asserted-by":"publisher","first-page":"2203","DOI":"10.1101\/gad.9.18.2203","volume":"9","author":"S Fiering","year":"1995","unstructured":"Fiering S, Epner E, Robinson K, Zhuang Y, Telling A, Hu M, Martin DI, Enver T, Ley TJ and Groudine M (1995) Targeted deletion of 5\u2032HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus. Genes Dev 9:2203\u20132213","journal-title":"Genes Dev"},{"key":"7_CR24","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1093\/intimm\/8.1.115","volume":"8","author":"C Chen","year":"1996","unstructured":"Chen C and Birshtein BK (1996) A region of 20 bp repeats lies 3\u2032 of human Ig Cal and Co2 genes. Int Immunol 8:115\u2013122","journal-title":"Int Immunol"},{"key":"7_CR25","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/0378-1119(95)00677-X","volume":"166","author":"G Gualandi","year":"1995","unstructured":"Gualandi G, Frezza D, Scotto d\u2019Abusco A, Bianchi E, Gargano S, Giorgi S, Fruscalzo A and Calef E (1995) Integration of a Epstein-Barr virus episome into the gene encoding immunoglobulin heavy-chain alpha 1 in a lymphoblastoid cell line. Gene 166:221\u2013226","journal-title":"Gene"},{"key":"7_CR26","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1006\/geno.1996.0338","volume":"35","author":"HK Kang","year":"1996","unstructured":"Kang HK and Cox DW (1996) Tandem repeats 3\u2032 of the IgHA genes in the human immunoglobulin heavy chain gene cluster. Genomics 35:189\u2013195","journal-title":"Genomics"},{"key":"7_CR27","doi-asserted-by":"crossref","first-page":"5677","DOI":"10.1128\/JVI.66.9.5677-5681.1992","volume":"66","author":"G Gualandi","year":"1992","unstructured":"Gualandi G, Santolini E and Calef E (1992) Epstein-Barr virus DNA recombines via latent origin of replication with the human genome in the lymphoblastoid cell line RGN1. J Virol 66:5677\u20135681","journal-title":"J Virol"},{"key":"7_CR28","doi-asserted-by":"crossref","unstructured":"Bergsagel PL, Chesi M, Nardini E, Brents LA, Kirby SL and Kuehl WM (1997) Promiscuous translocations into IgH switch regions in multiple myeloma. Proc Natl Acad Sci, in press","DOI":"10.1073\/pnas.93.24.13931"}],"container-title":["Current Topics in Microbiology and Immunology","C-Myc in B-Cell Neoplasia"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-642-60801-8_7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,11]],"date-time":"2024-04-11T08:33:46Z","timestamp":1712824426000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-642-60801-8_7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997]]},"ISBN":["9783642645600","9783642608018"],"references-count":28,"URL":"https:\/\/doi.org\/10.1007\/978-3-642-60801-8_7","relation":{},"ISSN":["0070-217X","2196-9965"],"issn-type":[{"value":"0070-217X","type":"print"},{"value":"2196-9965","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997]]}}}