{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:55:29Z","timestamp":1777467329224,"version":"3.51.4"},"publisher-location":"Berlin, Heidelberg","reference-count":64,"publisher":"Springer Berlin Heidelberg","isbn-type":[{"value":"9783540136705","type":"print"},{"value":"9783642699283","type":"electronic"}],"license":[{"start":{"date-parts":[[1985,1,1]],"date-time":"1985-01-01T00:00:00Z","timestamp":473385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[1985,1,1]],"date-time":"1985-01-01T00:00:00Z","timestamp":473385600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1985]]},"DOI":"10.1007\/978-3-642-69928-3_5","type":"book-chapter","created":{"date-parts":[[2011,12,6]],"date-time":"2011-12-06T06:37:20Z","timestamp":1323153440000},"page":"43-60","source":"Crossref","is-referenced-by-count":17,"title":["The Role of Receptors in 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Toxicity"],"prefix":"10.1007","author":[{"given":"L.","family":"Dencker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"5_CR1","first-page":"197","volume":"21","author":"R d\u2019Argy","year":"1984","unstructured":"d\u2019Argy R, Hassoun E, Dencker L (1984) Teratogenicity of TCDD and the congener 3,3\u2019,4,4\u2019tetrachloroazoxybenzene in sensitive and nonsensitive mouse strains after reciprocal blastocyst transfer Toxicol Lett 21: 197\u2013202","journal-title":"Teratogenicity of TCDD and the congener 3,3\u2019,4,4\u2019tetrachloroazoxybenzene in sensitive and nonsensitive mouse strains after reciprocal blastocyst transfer Toxicol Lett"},{"key":"5_CR2","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/0041-008X(75)90166-0","volume":"31","author":"PW Beatty","year":"1975","unstructured":"Beatty PW, Lemack KJ, Holscher MA, Neal RA (1975) Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin ( TCDD) on mammalian cells in tissue culture. Toxicol Appl Pharmacol 31: 309\u2013312","journal-title":"Toxicol Appl Pharmacol"},{"key":"5_CR3","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/0006-291X(76)90029-2","volume":"68","author":"P Beatty","year":"1976","unstructured":"Beatty P, Neal RA (1976) Induction of DT-diaphorase by 2,3,7,8-tetrachlorodibenzo p-dioxin ( TCDD ). Biochem Biophys Res Commun 68: 197\u2013204","journal-title":"Biochem Biophys Res Commun"},{"key":"5_CR4","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/0378-4274(82)90276-4","volume":"10","author":"SW Bigelow","year":"1982","unstructured":"Bigelow SW, Nebert DW (1982) The Ah regulatory gene product. Survey of nineteen polycyclic aromatic compounds\u2019 and fifteen benzo(a)pyrene metabolites\u2019 capacity to bind to the cytosolic receptor. Toxicol Lett 10: 109\u2013118","journal-title":"Toxicol Lett"},{"key":"5_CR5","first-page":"3172","volume":"39","author":"JMBD Carlstedt","year":"1979","unstructured":"Carlstedt-Duke JMB (1979) Tissue distribution of the receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat. Cancer Res 39: 3172\u20133176","journal-title":"Cancer Res"},{"key":"5_CR6","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1016\/0378-4274(78)90041-3","volume":"2","author":"JD Carlstedt","year":"1978","unstructured":"Carlstedt-Duke J, Elfstr\u00f6m G, Snochowski M, H\u00f6gberg B, Gustafsson J-A (1978) Detection of the 2,3,7,8-tetrachlorodibenzo-p-dioxin ( TCDD) receptor in rat liver by isoelectric focusing in polyacrylamide gels. Toxicol Lett 2: 365\u2013373","journal-title":"Toxicol Lett"},{"key":"5_CR7","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/0304-4165(81)90386-X","volume":"672","author":"JMBD Carlstedt","year":"1981","unstructured":"Carlstedt-Duke JMB, Harnemo U-B, H\u00f6gberg B, Gustafsson JA (1981) Interaction of hepatic receptor protein for 2,3,7,8-tetrachlorodibenzo-p-dioxin with DNA. Biochim Biophys Acta 672: 131\u2013141","journal-title":"Biochim Biophys Acta"},{"key":"5_CR8","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1007\/BF01685572","volume":"16","author":"KD Courtney","year":"1976","unstructured":"Courtney KD (1976) Mouse teratology studies with chlorodibenzo-p-dioxins. Bull Environ Contam Toxicol 16: 674\u2013681","journal-title":"Bull Environ Contam Toxicol"},{"key":"5_CR9","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1016\/0041-008X(71)90282-1","volume":"20","author":"KD Courtney","year":"1971","unstructured":"Courtney KD, Moore JA (1971) Teratology studies with 2,4,5-trichlorophenoxyacetic acid and 2,3,7,8tetrachlorodibenzo -p-dioxin. Toxicol Appl Pharmacol 20: 396\u2013403","journal-title":"Toxicol Appl Pharmacol"},{"key":"5_CR10","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0026-895X(25)11452-1","volume":"27","author":"L Dencker","year":"1985","unstructured":"Dencker L, Hassoun E, d\u2019Argy R, Alm G (1985) Fetal thymus organ culture as an in vitro model for the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin and its congeners. Mol Pharmacol 27: 133\u2013140","journal-title":"Mol Pharmacol"},{"key":"5_CR11","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1002\/tcm.1770010408","volume":"1","author":"L Dencker","year":"1981","unstructured":"Dencker L, Pratt RM (1981) Association between the presence of the Ah receptor in embryonic murine tissues and sensitivity to TCDD-induced cleft palate. Teratogens Carcinogens Mutagens 1: 399\u2013406","journal-title":"Teratogens Carcinogens Mutagens"},{"key":"5_CR12","doi-asserted-by":"publisher","first-page":"2343","DOI":"10.1016\/0006-2952(78)90142-9","volume":"27","author":"RA Dietrich","year":"1978","unstructured":"Dietrich RA, Bludeau P, Roger M, Schmuck J (1978) Induction of aldehyde dehydrogenases. Biochem Pharmacol 27: 2343\u20132347","journal-title":"Biochem Pharmacol"},{"key":"5_CR13","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1080\/15287397709529578","volume":"3","author":"RE Faith","year":"1977","unstructured":"Faith RE, Moore JA (1977) Impairment of thymus-dependent immune functions by exposure of the developing immune system to 2,3,7,8-tetrachlorodibenzo-p-dioxin ( TCDD ). J Toxicol Environ Health 3: 451\u2013464","journal-title":"J Toxicol Environ Health"},{"key":"5_CR14","doi-asserted-by":"publisher","first-page":"3524","DOI":"10.1073\/pnas.77.6.3524","volume":"77","author":"SM Galloway","year":"1980","unstructured":"Galloway SM, Perry PE, Meneses J, Nebert DW, Pedersen RA (1980) Cultured mouse embryos metabolize benzo(a)pyrene during early gestation. Genetic differences detectable by sister chromatide exchange. Proc Natl Acad Sci USA 77: 3524\u20133528","journal-title":"Proc Natl Acad Sci USA"},{"key":"5_CR15","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/S0026-895X(25)14997-3","volume":"26","author":"TA Gasiewicz","year":"1984","unstructured":"Gasiewicz TA, Rucci G (1984a) Cytosolic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin. Mol Pharmacol 26: 90\u201398","journal-title":"Mol Pharmacol"},{"key":"5_CR16","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/0304-4165(84)90007-2","volume":"798","author":"TA Gasiewicz","year":"1984","unstructured":"Gasiewicz TA, Rucci G (1984b) Examination and rapid analysis of hepatic cytosolic receptors for 2,3,7,8-tetrachlorodibenzo-p-dioxin using gel-permeation high performance liquid chromatography. Biochim Biophys Acta 798: 37\u201345","journal-title":"Biochim Biophys Acta"},{"key":"5_CR17","first-page":"151","volume-title":"Halogenated biphenyls, terphenyls, naphthalenes, dibenzodioxins and related products","author":"JA Goldstein","year":"1980","unstructured":"Goldstein JA (1980) Structure-activity relationships for the biochemical effects and the relationship to toxicity. In: Kimbrough RD (ed) Halogenated biphenyls, terphenyls, naphthalenes, dibenzodioxins and related products. Elsevier\/North-Holland Biomedical Press, Amsterdam, pp 151\u2013190"},{"key":"5_CR18","doi-asserted-by":"crossref","first-page":"9814","DOI":"10.1016\/S0021-9258(19)83589-5","volume":"254","author":"WF Greenlee","year":"1979","unstructured":"Greenlee WF, Poland A (1979) Nuclear uptake of 2,3,7,8-tetrachlorodibenzo-p-dioxin in C57BL\/6J and DBA\/2J mice. J Biol Chem 254: 9814\u20139821","journal-title":"J Biol Chem"},{"key":"5_CR19","doi-asserted-by":"crossref","first-page":"4584","DOI":"10.1016\/S0021-9258(19)69475-5","volume":"9","author":"RR Hannah","year":"1981","unstructured":"Hannah RR, Nebert DW, Eisen HJ (1981) Regulatory gene product of the Ah complex. Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3-methylcholanthrene binding to several moieties in mouse liver cytosol. J Biol Chem 9: 4584\u20134590","journal-title":"J Biol Chem"},{"key":"5_CR20","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/0378-4274(82)90185-0","volume":"12","author":"EM Hassoun","year":"1982","unstructured":"Hassoun EM, Dencker L (1982) TCDD embryotoxicity in the mouse may be enhanced by \/3-naphthoflavone, another ligand of the Ah-receptor. Toxicology Letterl 12: 191\u2013198","journal-title":"Toxicology Letterl"},{"key":"5_CR21","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1080\/15287398409530584","volume":"14","author":"E Hassoun","year":"1984","unstructured":"Hassoun E, d\u2019Argy R, Dencker L (1984a) Teratogenicity of 2,3,7,8-tetrachlorodibenzofuran in the mouse. J Toxicol Environ Health 14: 337\u2013351","journal-title":"J Toxicol Environ Health"},{"key":"5_CR22","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/0378-4274(84)90007-9","volume":"23","author":"E Hassoun","year":"1984","unstructured":"Hassoun E, d\u2019Argy R, Dencker L, Lundin L-G, Borwell P (1984b) Teratogenicity of 2,3,7,8tetrachlorodibenzofuran in BXD recombinant inbred strains. Toxicol Lett 23: 37\u201342","journal-title":"Toxicol Lett"},{"key":"5_CR23","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1007\/BF00316581","volume":"55","author":"E Hassoun","year":"1984","unstructured":"Hassoun E, d\u2019Argy R, Dencker L, Sundstr\u00f6m G (1984c) Teratological studies on the TCDD congener 3,3\u2019,4,4\u2019-tetrachloroazoxybenzene in sensitive and nonsensitive mouse strains: evidence for direct effect on embryonic tissues. Arch Toxicol 55: 20\u201326","journal-title":"Arch Toxicol"},{"key":"5_CR24","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1038\/220702a0","volume":"220","author":"GR Higginbotham","year":"1968","unstructured":"Higginbotham GR, Huang A, Firestone D, Verrett J, Ress J, Campbell AD (1968) Chemical and toxicological evaluations of isolated and synthetic chloro derivatives of dibenzo-p-dioxin. Nature 220: 702\u2013703","journal-title":"Nature"},{"key":"5_CR25","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1016\/0006-291X(80)91446-1","volume":"96","author":"K Ishidate","year":"1980","unstructured":"Ishidate K, Tsurouka M, Nakazawa Y (1980) Induction of choline kinase by polycyclic aromatic hydrocarbon carcinogens in rat liver. Biochem Biophys Res Commun 96: 946\u2013952","journal-title":"Biochem Biophys Res Commun"},{"key":"5_CR26","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/0041-008X(81)90009-0","volume":"61","author":"KG Jones","year":"1981","unstructured":"Jones KG, Cole FM, Sweeney GD (1981) The role of iron in the toxicity of 2,3,7,8-tetrachlorodibenzo-pdioxin ( TCDD ). Toxicol Appl Pharmacol 61: 74\u201388","journal-title":"Toxicol Appl Pharmacol"},{"key":"5_CR27","first-page":"631","volume":"17","author":"KG Jones","year":"1977","unstructured":"Jones KG, Sweeney GD (1977) Association between induction of aryl hydrocarbon hydroxylase and depression of uroporphyrinogen decarboxylase activity. Res Commun Chem Pathol Pharmacol 17: 631\u2013637","journal-title":"Res Commun Chem Pathol Pharmacol"},{"key":"5_CR28","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/0041-008X(80)90379-8","volume":"53","author":"KG Jones","year":"1980","unstructured":"Jones KG, Sweeney GD (1980) Dependence of the porphyrogenic effect of 2,3,7,8-tetrachlorodibenzo-pdioxin upon inheritance of aryl hydrocarbon hydroxylase responsiveness. Toxicol Appl Pharmacol 53: 42\u201349","journal-title":"Toxicol Appl Pharmacol"},{"key":"5_CR29","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1111\/j.1365-3083.1976.tb00304.x","volume":"5","author":"R Juhlin","year":"1976","unstructured":"Juhlin R, Alm GV (1976) Morphologic and antigenic maturation of lymphocytes in the mouse thymus in vitro. Scand J Immunol 5: 497\u2013503","journal-title":"Scand J Immunol"},{"key":"5_CR30","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1159\/000455531","volume":"1","author":"GF Kahl","year":"1980","unstructured":"Kahl GF, Friederici DE, Bigelow SW, Okey AB, Nebert DW (1980) Ontogenetic expression of regulatory and structural gene products associated with the Ah locus. Dev Pharmacol Ther 1: 137\u2013162","journal-title":"Dev Pharmacol Ther"},{"key":"5_CR31","first-page":"425","volume-title":"Extrahepatic Drug Metabolism and Chemical Carcinogenesis. Elsevier Science Publishers BV","author":"SO K\u00e4renlampi","year":"1983","unstructured":"K\u00e4renlampi SO, Legraverend C, Lalley PA, Kozak CA, Nebert DW (1983) Assignment of the Ah locus to mouse chromosome 17. In: Rydstr\u00f6m J, Montelius J, Bengtsson M (eds) Extrahepatic Drug Metabolism and Chemical Carcinogenesis. Elsevier Science Publishers BV pp 425\u2013426"},{"key":"5_CR32","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/0041-008X(80)90163-5","volume":"54","author":"JC Knutson","year":"1980","unstructured":"Knutson JC, Poland A (1980a) 2,3,7,8-Tetrachlorodibenzo p-dioxin: failure to demonstrate toxicity in twenty-three cultured cell types. Toxicol Appl Pharmacol 54: 377\u2013383","journal-title":"Toxicol Appl Pharmacol"},{"key":"5_CR33","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/0092-8674(80)90151-8","volume":"22","author":"JC Knutson","year":"1980","unstructured":"Knutson JC, Poland A (1980b) Keratinization of mouse teratoma cell line XB produced by 2,3,7,8tetrachlorodibenzo p-dioxin: an in vitro model of toxicity. Cell 22: 27\u201336","journal-title":"Cell"},{"key":"5_CR34","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/0092-8674(82)90028-9","volume":"30","author":"JC Knutson","year":"1982","unstructured":"Knutson JC, Poland A (1982) Response of murine epidermis to 2,3,7,8-tetrachlorodibenzo-p-dioxin; interaction of the ah and hr loci. Cell 30: 225\u2013234","journal-title":"Cell"},{"key":"5_CR35","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1016\/0024-3205(74)90324-5","volume":"15","author":"RE Kouri","year":"1974","unstructured":"Kouri RE, Ratrie H, Atlas SA, Niwa A, Nebert DW (1974) Aryl hydrocarbon hydroxylase induction in human lymphocyte cultures by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Life Sci 15: 585\u2013595","journal-title":"Life Sci"},{"key":"5_CR36","doi-asserted-by":"publisher","first-page":"2459","DOI":"10.1016\/0006-2952(82)90054-5","volume":"31","author":"RN Kurl","year":"1982","unstructured":"Kurl RN, Lund J, Poellinger L, Gustafsson J-A, (1982) Differential effect of 2,3,7,8-tetrachlorodibenzop-dioxin on molecular RNA polymerase activity in the rat liver and thymus. Biochem Pharmacol 31: 2459\u20132462","journal-title":"Biochem Pharmacol"},{"key":"5_CR37","doi-asserted-by":"crossref","first-page":"6402","DOI":"10.1016\/S0021-9258(20)65155-9","volume":"257","author":"C Legraverend","year":"1982","unstructured":"Legraverend C, Hannah RR, Eisen HJ, Owens IS, Nebert DW, Hankinson O (1982) Regulatory gene product of the Ah locus. Characterization of receptor mutants among mouse hepatoma clones. J Biol Chem 257: 6402\u20136407","journal-title":"J Biol Chem"},{"key":"5_CR38","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/0041-008X(81)90417-8","volume":"61","author":"TA Marks","year":"1981","unstructured":"Marks TA, Kimmel GL, Staples RE (1981) Influence of symmetrical polychlorinated biphenyl isomers on embryo and fetal development in mice. Toxicol Appl Pharmacol 61: 269\u2013276","journal-title":"Toxicol Appl Pharmacol"},{"key":"5_CR39","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1111\/j.1432-1033.1982.tb06518.x","volume":"123","author":"ME Mason","year":"1982","unstructured":"Mason ME, Okey AB (1982) Cytosolic and nuclear binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin to the Ah receptor in extra-hepatic tissues of rats and mice. Eur J Biochem 123: 209\u2013215","journal-title":"Eur J Biochem"},{"key":"5_CR40","first-page":"109","volume-title":"Halogenated biphenyls, terphenyls, naphthalenes, dibenzodioxins and related compounds","author":"EE Mcconnell","year":"1980","unstructured":"McConnell EE (1980) Acute and chronic toxicity, carcinogenicity, reproduction, teratogenicity and mutagenicity in animals. In: Kimbrough RD (ed) Halogenated biphenyls, terphenyls, naphthalenes, dibenzodioxins and related compounds. Elsevier\/North-Holland Biomedical Press, Amsterdam, pp 109\u2013150"},{"key":"5_CR41","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1146\/annurev.pa.21.040181.002243","volume":"21","author":"DW Nebert","year":"1981","unstructured":"Nebert DW, Eisen HJ, Negishi M, Lang MA, Hjelmeland LM (1981) Genetic mechanisms controlling the induction of polysubstrate monooxygenase (P-450) activities. Ann Rev Pharmacol Toxicol 21: 431\u2013462","journal-title":"Ann Rev Pharmacol Toxicol"},{"key":"5_CR42","doi-asserted-by":"publisher","first-page":"401","DOI":"10.3109\/10409237909105427","volume":"6","author":"DW Nebert","year":"1979","unstructured":"Nebert DW, Jensen NM (1979) The Ah locus: Genetic regulation of the metabolism of carcinogens, drugs and other environmental chemicals by cytochrome P-450-mediated monooxygenases. CRC Crit Rev Biochem 6: 401\u2013437","journal-title":"CRC Crit Rev Biochem"},{"key":"5_CR43","doi-asserted-by":"crossref","first-page":"6836","DOI":"10.1016\/S0021-9258(18)43649-6","volume":"255","author":"DW Nebert","year":"1980","unstructured":"Nebert DW, Jensen N, Perry JW, Oka T (1980) Association between ornithine decarboxylase induction and the Ah locus in mice treated with polycyclic aromatic compounds. J Biol Chem 255: 6836\u20136842","journal-title":"J Biol Chem"},{"key":"5_CR44","doi-asserted-by":"crossref","first-page":"11636","DOI":"10.1016\/S0021-9258(19)86532-8","volume":"254","author":"AB Okey","year":"1979","unstructured":"Okey AB, Bondy GP, Mason ME, Kahl GF, Eisen HJ, Guenthner TM, Nebert DW (1979) Regulatory gene product of the Ah locus: Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation. J Biol Chem 254: 11636\u201311648","journal-title":"J Biol Chem"},{"key":"5_CR45","doi-asserted-by":"crossref","first-page":"11415","DOI":"10.1016\/S0021-9258(19)70307-X","volume":"255","author":"AB Okey","year":"1980","unstructured":"Okey AB, Bondy GP, Mason ME, Nebert DW, Forster-Gibson CJ, Muncan J, Dufresne MJ (1980) Temperature-dependent cytosol-to-nucleus translocation of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in continuous cell culture lines. J Biol Chem 255: 11415\u201311422","journal-title":"J Biol Chem"},{"key":"5_CR46","first-page":"389","volume-title":"Extrahepatic drug metabolism and chemical carcinogenesis","author":"AB Okey","year":"1983","unstructured":"Okey AB, Mason ME, Vella LM (1983) The Ah receptor: species and tissue variation in binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin and carcinogenic aromatic hydrocarbons. In: Rydstr\u00f6m J, Montelius J, Bengtsson M (eds) Extrahepatic drug metabolism and chemical carcinogenesis. Elsevier Scientific Publishers, Amsterdam, pp 389\u2013399"},{"key":"5_CR47","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1016\/S0021-9258(17)40437-6","volume":"252","author":"IS Owens","year":"1977","unstructured":"Owens IS (1977) Genetic regulation of UDP-glucuronosyltransferase induction by polycyclic aromatic compounds in mice. J Biol Chem 252: 2827\u20132833","journal-title":"J Biol Chem"},{"key":"5_CR48","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/S0026-895X(25)14014-5","volume":"9","author":"A Poland","year":"1973","unstructured":"Poland A, Glover E (1973) Chlorinated dibenzo-p-dioxins: potent inducers of S-aminolevulinic acid synthetase and aryl hydrocarbon hydroxylase. II. A study of the structure-activity relationship. Mol Pharmacol 9: 736\u2013747","journal-title":"Mol Pharmacol"},{"key":"5_CR49","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/S0026-895X(25)12455-3","volume":"13","author":"A Poland","year":"1977","unstructured":"Poland A, Glover E (1977) Chlorinated biphenyl induction of aryl hydrocarbon hydroxylase activity: a study of the structure-activity relationship. Mol Pharmacol 13: 924\u2013938","journal-title":"Mol Pharmacol"},{"key":"5_CR50","first-page":"3341","volume":"39","author":"A Poland","year":"1979","unstructured":"Poland A, Glover E (1979) An estimate of the maximum in vivo covalent binding of 2,3,7,8tetrachlorodibenzo -p-dioxin to rat liver protein, ribosomal RNA, and DNA. Cancer Res 39: 3341\u20133344","journal-title":"Cancer Res"},{"key":"5_CR51","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/S0026-895X(25)14074-1","volume":"17","author":"A Poland","year":"1980","unstructured":"Poland A, Glover E (1980) 2,3,7,8-tetrachlorodibenzo p-dioxin: Segregation of toxicity with the Ah-locus. Mol Pharmacol 17: 86\u201394","journal-title":"Mol Pharmacol"},{"key":"5_CR52","doi-asserted-by":"crossref","first-page":"4936","DOI":"10.1016\/S0021-9258(17)33205-2","volume":"251","author":"A Poland","year":"1976","unstructured":"Poland A, Glover E, Kende AS (1976a) Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. J Biol Chem 251: 4936\u20134946","journal-title":"J Biol Chem"},{"key":"5_CR53","doi-asserted-by":"publisher","first-page":"627","DOI":"10.1126\/science.136041","volume":"194","author":"A Poland","year":"1976","unstructured":"Poland A, Glover E, Kende AS, DeCamp M, Giandomenico CM (1976b) 3,4,3\u2019,4\u2019-tetrachloroazoxybenzene and azobenzene: Potent inducers of aryl hydrocarbon hydroxylase. Science 194: 627\u2013630","journal-title":"Science"},{"key":"5_CR54","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1146\/annurev.pa.22.040182.002505","volume":"22","author":"A Poland","year":"1982","unstructured":"Poland A, Knutson JC (1982) 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Ann Rev Pharmacol Toxicol 22: 517\u2013554","journal-title":"Ann Rev Pharmacol Toxicol"},{"key":"5_CR55","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1002\/tcm.1770040505","volume":"4","author":"RM Pratt","year":"1984","unstructured":"Pratt RM, Dencker L, Diewert VM (1984) 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced cleft palate in the mouse: evidence for alterations in palatal shelf fusion. Teratogens Carcinogens Mutagens 4: 427\u2013436","journal-title":"Teratogens Carcinogens Mutagens"},{"key":"5_CR56","first-page":"62A","volume":"21","author":"RM Pratt","year":"1980","unstructured":"Pratt RM, Dencker L, Yoneda T, Diewert VM (1980) Dioxin-induced cleft palate in the mouse. Teratology 21: 62A\u201363A","journal-title":"Teratology"},{"key":"5_CR57","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/0092-8674(75)90183-X","volume":"6","author":"JG Rheinwald","year":"1975","unstructured":"Rheinwald JG, Green H (1975) Formation of a keratinizing epithelium in culture by a cloned cell line derived from a teratoma. Cell 6: 317\u2013330","journal-title":"Cell"},{"key":"5_CR58","volume-title":"Catalog of Teratogenic Agents (3:rd edition)","author":"TH Shepard","year":"1980","unstructured":"Shepard TH (1980) Catalog of Teratogenic Agents (3:rd edition). The Johns Hopkins University Press, Baltimore."},{"key":"5_CR59","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1111\/j.1365-3083.1976.tb03040.x","volume":"5","author":"G Tufveson","year":"1976","unstructured":"Tufveson G, Juhlin R, Steineck G, Alm GV (1976) Role of the thymus in generation of lymphocyte functions. I. Demonstration of lymphocytes reactive to mitogens and allergenic cells in the embryonic mouse thymus in organ culture. Scand J Immunol 5: 901\u2013907","journal-title":"Scand J Immunol"},{"key":"5_CR60","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/0300-483X(80)90007-4","volume":"15","author":"MJ van Logten","year":"1980","unstructured":"van Logten MJ, Gupta BN, McConnell EE, Moore JA (1980) Role of the endocrine system in the action of 2,3,7,8-tetrachlorodibenzo-p-dioxin ( TCDD) on the thymus. Toxicology 15: 135\u2013144","journal-title":"Toxicology"},{"key":"5_CR61","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1016\/S0021-9258(17)43554-X","volume":"259","author":"JP Whitlock","year":"1984","unstructured":"Whitlock JP Jr, Galeazzi DR (1984) 2,3,7,8-Tetrachlorodibenzo-p-dioxin receptors in wild type and variant mouse hepatoma cells. J Biol Chem 259: 980\u2013985","journal-title":"J Biol Chem"},{"key":"5_CR62","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1159\/000231268","volume":"47","author":"JG Vos","year":"1974","unstructured":"Vos JG, Moore JA (1974) Suppression of cellular immunity in rats and mice by maternal treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Int Arch Allergy 47: 777\u2013794","journal-title":"Int Arch Allergy"},{"key":"5_CR63","doi-asserted-by":"publisher","first-page":"67","DOI":"10.3109\/10408447709101342","volume":"5","author":"JG Vos","year":"1977","unstructured":"Vos JG, Moore JA (1977) Immune suppression as related to toxicology. CRC Crit Rev Toxicol 5: 67\u2013101","journal-title":"CRC Crit Rev Toxicol"},{"key":"5_CR64","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/0300-483X(82)90097-X","volume":"23","author":"JG Vos","year":"1982","unstructured":"Vos JG, van Leeuwen FXR, de Jong P (1982) Acnegenic activity of 3-methylcholanthrene and benzo(a)pyrene, and a comparative study with 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rabbit and hairless mouse. Toxicology 23: 187\u2013196","journal-title":"Toxicology"}],"container-title":["Archives of Toxicology","Receptors and Other Targets for Toxic Substances"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-642-69928-3_5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T22:59:06Z","timestamp":1741993146000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-3-642-69928-3_5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985]]},"ISBN":["9783540136705","9783642699283"],"references-count":64,"URL":"https:\/\/doi.org\/10.1007\/978-3-642-69928-3_5","relation":{},"ISSN":["0171-9750"],"issn-type":[{"value":"0171-9750","type":"print"}],"subject":[],"published":{"date-parts":[[1985]]}}}