{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T18:23:25Z","timestamp":1790879005092,"version":"4.1.0"},"publisher-location":"Berlin, Heidelberg","reference-count":52,"publisher":"Springer Berlin Heidelberg","isbn-type":[{"value":"9783642077999","type":"print"},{"value":"9783662057674","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2002]]},"DOI":"10.1007\/978-3-662-05767-4_7","type":"book-chapter","created":{"date-parts":[[2013,1,14]],"date-time":"2013-01-14T06:59:59Z","timestamp":1358146799000},"page":"143-164","source":"Crossref","is-referenced-by-count":30,"title":["Bacillus anthracis Genetics and Virulence Gene Regulation"],"prefix":"10.1007","author":[{"given":"T. M.","family":"Koehler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"7_CR1","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1046\/j.1365-2672.1998.00405.x","volume":"84","author":"L Baillie","year":"1998","unstructured":"Baillie L, Moir A, Manchee R (1998) The expression of the protective antigen of Bacillus anthracis in Bacillus subtilis. J Appl Microbiol 84: 741\u2013746","journal-title":"J Appl Microbiol"},{"key":"7_CR2","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.1128\/IAI.57.8.2295-2300.1989","volume":"57","author":"JM Bartkus","year":"1989","unstructured":"Bartkus JM, Leppla SH (1989) Transcriptional regulation of the protective antigen gene of Bacillus anthracis. Infect Immun 57: 2295\u20132300","journal-title":"Infect Immun"},{"key":"7_CR3","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1128\/JB.162.2.543-550.1985","volume":"162","author":"L Battisti","year":"1985","unstructured":"Battisti L, Green BD, Thorne CB (1985) Mating system for transfer of plasmids among Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis. J Bacteriol 162: 543\u2013550","journal-title":"J Bacteriol"},{"key":"7_CR4","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/0378-1119(89)90335-1","volume":"81","author":"TS Bragg","year":"1989","unstructured":"Bragg TS, Robertson DL (1989) Nucleotide sequence and analysis of the lethal factor gene (lef) from Bacillus anthracis. Gene 81: 45\u201354","journal-title":"Gene"},{"key":"7_CR5","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1111\/j.1365-2958.1994.tb02176.x","volume":"14","author":"DP Brown","year":"1994","unstructured":"Brown DP, Ganova-Raeva L, Green BD, Wilkinson SR, Young M, Youngman P (1994) Characterization of spo0A homologues in diverse Bacillus and Clostridium species identifies a probable DNA-binding domain. Mol Microbiol 14: 411\u2013426","journal-title":"Mol Microbiol"},{"key":"7_CR6","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1111\/j.1574-6968.1992.tb05495.x","volume":"98","author":"A Cataldi","year":"1992","unstructured":"Cataldi A, Fouet A, Mock M (1992) Regulation of pag gene expression in Bacillus anthracis: use of a pag-lacZ transcriptional fusion. FEMS Microbiol Lett 98: 89\u201394","journal-title":"FEMS Microbiol Lett"},{"key":"7_CR7","doi-asserted-by":"crossref","first-page":"2576","DOI":"10.1128\/IAI.65.7.2576-2582.1997","volume":"65","author":"Z Dai","year":"1997","unstructured":"Dai Z, Koehler TM. (1997) Regulation of anthrax toxin activator gene (atxA) expression in Bacillus anthracis: Temperature, not CO2\/bicarbonate, affects AtxA synthesis. Infect Immun 65: 2576\u20132582","journal-title":"Infect Immun"},{"key":"7_CR8","doi-asserted-by":"publisher","first-page":"1171","DOI":"10.1111\/j.1365-2958.1995.tb02340.x","volume":"16","author":"Z Dai","year":"1995","unstructured":"Dai Z, Sirard J-C, Mock M, Koehler TM (1995) The atxA gene product activates transcription of the anthrax toxin genes and is essential for virulence. Mol Microbiol 16: 1171\u20131181","journal-title":"Mol Microbiol"},{"key":"7_CR9","volume-title":"Cell-cell signaling in bacteria","author":"GM Dunny","year":"1999","unstructured":"Dunny GM, Winans SC (1999) Cell-cell signaling in bacteria. Washington, DC: ASM Press"},{"key":"7_CR10","doi-asserted-by":"publisher","first-page":"5036","DOI":"10.1128\/JB.182.18.5036-5045.2000","volume":"182","author":"A Fouet","year":"2000","unstructured":"Fouet A, Namy O, Lambert G (2000) Characterization of the operon encoding the alternative sigma(B) factor from Bacillus anthracis and its role in virulence. J Bacteriol 182: 5036\u20135045","journal-title":"J Bacteriol"},{"key":"7_CR11","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1111\/j.1365-2958.1994.tb00328.x","volume":"11","author":"A Fouet","year":"1994","unstructured":"Fouet A, Sirard JC, Mock M (1994) Bacillus anthracis pXO1 virulence plasmid encodes a type 1 DNA topoisomerase. Mol Microbiol 11: 471\u2013479","journal-title":"Mol Microbiol"},{"key":"7_CR12","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1128\/IAI.49.2.291-297.1985","volume":"49","author":"BD Green","year":"1985","unstructured":"Green BD, Battisti L, Koehler TM, Thorne CB (1985) Demonstration of a capsule plasmid in Bacillus anthracis. Infect Immun 49: 291\u2013297","journal-title":"Infect Immun"},{"key":"7_CR13","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1128\/jb.171.1.104-113.1989","volume":"171","author":"BD Green","year":"1989","unstructured":"Green BD, Battisti L, Thorne CB (1989) Involvement of Tn4430 in transfer of Bacillus anthracis plasmids mediated by Bacillus thuringiensis plasmid pXO12. J Bacteriol 171: 104\u2013113","journal-title":"J Bacteriol"},{"key":"7_CR14","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1046\/j.1365-2958.1999.01485.x","volume":"33","author":"C Guidi-Rontani","year":"1999","unstructured":"Guidi-Rontani C, Pereira Y, Ruffie S, Sirard JC, Weber-Levy M, Mock M (1999a) Identification and characterization of a germination operon on the virulence plasmid pXO1 of Bacillus anthracis. Mol Microbiol 33: 407\u2013414","journal-title":"Mol Microbiol"},{"key":"7_CR15","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1046\/j.1365-2958.1999.01137.x","volume":"31","author":"C Guidi-Rontani","year":"1999","unstructured":"Guidi-Rontani C, Weber-Levy M, Labruyere E, Mock M (1999b) Germination of Bacillus anthracis spores within alveolar macrophages. Mol Microbiol 31: 9\u201317","journal-title":"Mol Microbiol"},{"key":"7_CR16","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1111\/j.1574-6968.1997.tb10242.x","volume":"147","author":"J Guignot","year":"1997","unstructured":"Guignot J, Mock M, Fouet A (1997) AtxA activates the transcription of genes harbored by both Bacillus anthracis virulence plasmids. FEMS Microbiol Lett 147: 203\u2013207","journal-title":"FEMS Microbiol Lett"},{"key":"7_CR17","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1128\/9781555817992.ch21","volume-title":"Bacillus subtilis and its close relatives","author":"JD Helman","year":"2002","unstructured":"Helman JD, Moran CP (2002) RNA polymerase and sigma factors. In: Bacillus subtilis and its close relatives. Sonenshein AL, Hoch JA and Losick R (eds) Washington, DC: ASM Press, pp. 289\u2013312"},{"key":"7_CR18","doi-asserted-by":"crossref","first-page":"3091","DOI":"10.1128\/IAI.65.8.3091-3099.1997","volume":"65","author":"AR Hoffmaster","year":"1997","unstructured":"Hoffmaster AR, Koehler TM (1997) The anthrax toxin activator gene atxA is associated with CO2-enhanced non-toxin gene expression in Bacillus anthracis. Infect Immun 65: 3091\u20133099","journal-title":"Infect Immun"},{"key":"7_CR19","doi-asserted-by":"crossref","first-page":"4485","DOI":"10.1128\/JB.181.15.4485-4492.1999","volume":"181","author":"AR Hoffmaster","year":"1999","unstructured":"Hoffmaster AR, Koehler TM (1999) Autogenous regulation of the Bacillus anthracis pag operon. J Bacteriol 181: 4485\u20134492","journal-title":"J Bacteriol"},{"key":"7_CR20","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1128\/IAI.58.2.303-308.1990","volume":"58","author":"BE Ivins","year":"1990","unstructured":"Iv ins BE, Welkos SL, Knudson GB, Little SF (1990) Immunization against anthrax with aromatic compound-dependent (Aro\u2013) mutants of Bacillus anthracis and with recombinant strains of Bacillus subtilis that produce anthrax protective antigen. Infect Immun 58: 303\u2013308","journal-title":"Infect Immun"},{"key":"7_CR21","first-page":"519","volume-title":"Bacillus anthracis. In: Gram-positive pathogens","author":"TM Koehler","year":"2000","unstructured":"Koehler TM (2000) Bacillus anthracis. In: Gram-positive pathogens. Fischetti VA, Novick RP, Ferretti JJ, Protnoy DA and Rood JI (eds) Washington, DC: ASM Press, pp 519\u2013528"},{"key":"7_CR22","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1128\/jb.176.3.586-595.1994","volume":"176","author":"TM Koehler","year":"1994","unstructured":"Koehler TM, Dai Z, Kaufman-Yarbray M (1994) Regulation of the Bacillus anthracis protective antigen gene: CO2 and a trans-acting element activate transcription from one of two promoters. J Bacteriol 176: 586\u2013595","journal-title":"J Bacteriol"},{"key":"7_CR23","doi-asserted-by":"crossref","first-page":"5271","DOI":"10.1128\/jb.169.11.5271-5278.1987","volume":"169","author":"TM Koehler","year":"1987","unstructured":"Koehler TM, Thorne CB (1987) Bacillus subtilis (natto) plasmid pLS20 mediates interspecies plasmid transfer. J Bacteriol 169: 5271\u20135278","journal-title":"J Bacteriol"},{"key":"7_CR24","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/S0076-6879(88)65019-1","volume":"165","author":"SH Leppla","year":"1988","unstructured":"Leppla SH (1988) Production and purification of anthrax toxin. Methods Enzymol 165: 103\u2013116","journal-title":"Methods Enzymol"},{"key":"7_CR25","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/0076-6879(91)95162-D","volume":"195","author":"SH Leppla","year":"1991","unstructured":"Leppla SH (1991) Purification and characterization of adenylyl cyclase from Bacillus anthracis. Methods Enzymol 195: 153\u2013168","journal-title":"Methods Enzymol"},{"key":"7_CR26","first-page":"371","volume":"2","author":"S Makino","year":"1988","unstructured":"Makino S, Sasakawa C, Uchida I, Terakado N,Yoshikawa M (1988) Cloning and CO2-dependent expression of the genetic region for encapsulation from Bacillus anthracis. Mol Microbiol 2: 371\u2013376","journal-title":"Cloning and CO2-dependent expression of the genetic region for encapsulation from Bacillus anthracis. Mol Microbiol"},{"key":"7_CR27","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1128\/jb.171.2.722-730.1989","volume":"171","author":"S-I Makino","year":"1989","unstructured":"Makino S-I, Uchida I, Terakado N, Sasakawa C, Yoshikawa M (1989) Molecular characterization and protein analysis of the cap region, which is essential for encapsulation in Bacillus anthracis. J Bacteriol 171: 722\u2013730","journal-title":"J Bacteriol"},{"key":"7_CR28","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1016\/0378-1119(94)00647-B","volume":"152","author":"R Marrero","year":"1995","unstructured":"Marrero R, Welkos SL (1995) The transformation frequency of plasmids into Bacillus anthracis is affected by adenine methylation. Gene 152: 75\u201378","journal-title":"Gene"},{"key":"7_CR29","doi-asserted-by":"crossref","first-page":"6619","DOI":"10.1128\/jb.177.22.6619-6624.1995","volume":"177","author":"KS Mciver","year":"1995","unstructured":"McIver KS, Heath AS, Green BD, Scott JR (1995) Specific binding of the activator Mga to promoter sequences of the emm and scpA genes in the group A streptococcus. J Bacteriol 177: 6619\u20136624","journal-title":"J Bacteriol"},{"key":"7_CR30","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1128\/IAI.39.1.371-376.1983","volume":"39","author":"P Mikesell","year":"1983","unstructured":"Mikesell P, Ivins BE, Ristroph JD, Dreier TM (1983) Evidence for plasmid-mediated toxin production in Bacillus anthracis. Infect Immun 39: 371\u2013376","journal-title":"Infect Immun"},{"key":"7_CR31","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/0378-1119(88)90342-3","volume":"64","author":"M Mock","year":"1988","unstructured":"Mock M, Labruyere E, Glaser P, Danchin A, Ullmann A (1988) Cloning and expression of the calmodulin-sensitive Bacillus anthracis adenylate cyclase in Escherichia coli. Gene 64: 277\u2013284","journal-title":"Gene"},{"key":"7_CR32","doi-asserted-by":"crossref","first-page":"6509","DOI":"10.1128\/JB.181.20.6509-6515.1999","volume":"181","author":"RT Okinaka","year":"1999","unstructured":"Okinaka RT, Cloud K, Hampton O, Hoffmaster A, Hill KK, Keim P, Koehler TM, Lamke G, Kumano S, Mahillon J, Manter D, Martinez Y, Ricke D, Svensson R, Jackson PJ (1999) The sequence and organization of pXO1, the large Bacillus anthracis plasmid harboring the anthrax toxin genes. J Bacteriol 181: 6509\u20136515","journal-title":"J Bacteriol"},{"key":"7_CR33","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1128\/jb.179.2.522-529.1997","volume":"179","author":"M O\u2019Reilly","year":"1997","unstructured":"O\u2019Reilly M, Devine KM (1997) Expression of AbrB, a transition state regulator from Bacillus subtilis, is growth phase dependent in a manner resembling that of Fis, the nucleoid binding protein from Escherichia coli. J Bacteriol 179: 522\u2013529","journal-title":"J Bacteriol"},{"key":"7_CR34","doi-asserted-by":"crossref","first-page":"3472","DOI":"10.1128\/IAI.59.10.3472-3477.1991","volume":"59","author":"C Pezard","year":"1991","unstructured":"Pezard C, Berche P, Mock M (1991) Contribution of individual toxin components to virulence of Bacillus anthracis. Infect Immun 59: 3472\u20133477","journal-title":"Infect Immun"},{"key":"7_CR35","first-page":"55","volume":"68","author":"DL Robertson","year":"1990","unstructured":"Robertson DL, Bragg TS, Simpson S, Kaspar R, Xie W, Tippetts MT (1990) Mapping and characterization of Bacillus anthracis plasmids pXO1 and pXO2. Salisbury Med Bull 68 (Spec Suppl): 55\u201358","journal-title":"Salisbury Med Bull"},{"key":"7_CR36","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1016\/0378-1119(88)90501-X","volume":"73","author":"DL Robertson","year":"1988","unstructured":"Robertson DL, Tippetts MT, Leppla SH (1988) Nucleotide sequence of the Bacillus anthracis edema factor gene (cya): a calmodulin-dependent adenylate cyclase. Gene 73: 363\u2013371","journal-title":"Gene"},{"key":"7_CR37","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1128\/JB.184.2.370-380.2002","volume":"184","author":"E Saile","year":"2002","unstructured":"Saile E, Koehler TM (2002) Control of anthrax toxin gene expression by the transition state regulator abrB. J Bacteriol 184: 370\u2013380","journal-title":"J Bacteriol"},{"key":"7_CR38","doi-asserted-by":"crossref","first-page":"5188","DOI":"10.1128\/jb.176.16.5188-5192.1994","volume":"176","author":"J-C Sirard","year":"1994","unstructured":"Sirard J-C, Mock M, Fouet A (1994) The three Bacillus anthracis toxin genes are coordinately regulated by bicarbonate and temperature. J Bacteriol 176:5188\u2013 5192","journal-title":"J Bacteriol"},{"key":"7_CR39","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1016\/0923-2508(96)81069-2","volume":"146","author":"J-C Sirard","year":"1995","unstructured":"Sirard J-C, Mock M, Fouet A (1995) Molecular tools for the study of transcriptional regulation in Bacillus anthracis. Res Microbiol 146: 729\u2013737","journal-title":"Res Microbiol"},{"key":"7_CR40","first-page":"757","volume-title":"Bacillus subtilis and other gram-positive bacteria","author":"MA Strauch","year":"1993","unstructured":"Strauch MA (1993) Abr, a transition state regulator. In: Bacillus subtilis and other gram-positive bacteria. Sonenshein AL, Hoch JA and Losick R (eds) Washington, DC: ASM Press, pp 757\u2013764"},{"key":"7_CR41","doi-asserted-by":"crossref","first-page":"6999","DOI":"10.1128\/jb.177.23.6999-7002.1995","volume":"177","author":"MA Strauch","year":"1995","unstructured":"Strauch MA (1995) Delineation of AbrB-binding sites on the Bacillus subtilis spo0H, kinB, ftsAZ, and pbpE promoters and use of a derived homology to identify a previously unsuspected binding site in the bsuB1 methylase promoter. J Bacteriol 177: 6999\u20137002","journal-title":"J Bacteriol"},{"key":"7_CR42","first-page":"113","volume-title":"Bacillus anthracis. In: Bacillus subtilis and Other Gram-Positive Bacteria: Biochemistry, Physiology, and Molecular Genetics. Sonenshein AL","author":"CB Thorne","year":"1993","unstructured":"Thorne CB (1993) Bacillus anthracis. In: Bacillus subtilis and Other Gram-Positive Bacteria: Biochemistry, Physiology, and Molecular Genetics. Sonenshein AL, Hoch JA and Losick R (eds) Washington, DC: American Society for Microbiology, pp 113\u2013124"},{"key":"7_CR43","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1128\/jb.170.5.2263-2266.1988","volume":"170","author":"MT Tippetts","year":"1988","unstructured":"Tippetts MT, Robertson DL (1988) Molecular cloning and expression of the Bacillus anthracis edema factor toxin gene: a calmodulin-dependent adenylate cyclase. J Bacteriol 170: 2263\u20132266","journal-title":"J Bacteriol"},{"key":"7_CR44","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1016\/0378-1119(91)90546-N","volume":"102","author":"P Trieu-Cuot","year":"1991","unstructured":"Trieu-Cuot P, Carlier C, Poyart-Salmeron C, Courvalin P (1991) Shuttle vectors containing a multiple cloning site and a lacZ alpha gene for conjugal transfer of DNA from Escherichia coli to gram-positive bacteria. Gene 102: 99\u2013104","journal-title":"Gene"},{"key":"7_CR45","first-page":"178","volume":"18","author":"I Uchida","year":"1987","unstructured":"Uchida I, Hashimoto K, Makino S, Sasakawa C,Yoshikawa M, Terakado N (1987) Restriction map of a capsule plasmid of Bacillus anthracis. Plasmid 18: 178\u2013181","journal-title":"Restriction map of a capsule plasmid of Bacillus anthracis. Plasmid"},{"key":"7_CR46","doi-asserted-by":"crossref","first-page":"5329","DOI":"10.1128\/jb.175.17.5329-5338.1993","volume":"175","author":"I Uchida","year":"1993","unstructured":"Uchida I, Hornung JM, Thorne CB, Klimpel KR, and Leppla SH (1993 a) Cloning and characterization of a gene whose product is a trans-activator of anthracis toxin synthesis. J Bacteriol 175: 5329\u20135338","journal-title":"J Bacteriol"},{"key":"7_CR47","doi-asserted-by":"crossref","unstructured":"Uchida I, Makino S,Sasakawa C,Yoshikawa M, Sugimoto C,Terakado N (1993 b) Identification of a novel gene, dep, associated with depolymerization of the capsular polymer in Bacillus anthracis. Mol Microbiol 9: 487\u2013496","DOI":"10.1111\/j.1365-2958.1993.tb01710.x"},{"key":"7_CR48","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1046\/j.1365-2958.1997.3041667.x","volume":"23","author":"I Uchida","year":"1997","unstructured":"Uchida I, Makino S, Sekizaki T, Terakado N (1997) Cross-talk to the genes for Bacillus anthracis capsule synthesis by atxA, the gene encoding the trans-activator of anthrax toxin synthesis. Mol Microbiol 23: 1229\u20131240","journal-title":"Mol Microbiol"},{"key":"7_CR49","first-page":"363","volume":"131","author":"I Uchida","year":"1985","unstructured":"Uchida I, Sekizaki T, Hashimoto K, Terakado N (1985) Association of encapsulation of Bacillus anthracis with a 60 megadalton plasmid. J Gen Microbiol 131: 363\u2013367","journal-title":"J Gen Microbiol"},{"key":"7_CR50","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0378-1119(94)00662-C","volume":"152","author":"NJ Vietri","year":"1995","unstructured":"Vietri NJ, Marrero R, Hoover TA, Welkos SL (1995) Identification and characterization of a trans-activator involved in the regulation of encapsulation by Bacillus anthracis. Gene 152: 1\u20139","journal-title":"Gene"},{"key":"7_CR51","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1016\/0092-8674(83)90402-6","volume":"34","author":"MH Vodkin","year":"1983","unstructured":"Vodkin MH, Leppla SH (1983) Cloning of the protective antigen gene of Bacillus anthracis. Cell 34: 693\u2013697","journal-title":"Cell"},{"key":"7_CR52","doi-asserted-by":"crossref","unstructured":"Welkos SL,Lowe JR, Eden-McCutchan F,Vodkin M,Leppla SH,Schmidt JJ (1988) Sequence and analysis of the DNA encoding protective antigen of Bacillus anthracis. Gene 69: 287\u2013300","DOI":"10.1016\/0378-1119(88)90439-8"}],"container-title":["Current Topics in Microbiology and Immunology","Anthrax"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-662-05767-4_7.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,6]],"date-time":"2021-05-06T11:28:40Z","timestamp":1620300520000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-662-05767-4_7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002]]},"ISBN":["9783642077999","9783662057674"],"references-count":52,"URL":"https:\/\/doi.org\/10.1007\/978-3-662-05767-4_7","relation":{},"ISSN":["0070-217X"],"issn-type":[{"value":"0070-217X","type":"print"}],"subject":[],"published":{"date-parts":[[2002]]}}}