{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T19:25:10Z","timestamp":1791141910920,"version":"4.1.0"},"publisher-location":"Vienna","reference-count":18,"publisher":"Springer Vienna","isbn-type":[{"value":"9783709172209","type":"print"},{"value":"9783709106518","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003]]},"DOI":"10.1007\/978-3-7091-0651-8_59","type":"book-chapter","created":{"date-parts":[[2011,8,8]],"date-time":"2011-08-08T05:05:36Z","timestamp":1312779936000},"page":"271-275","source":"Crossref","is-referenced-by-count":9,"title":["Antioxidant properties of the vasoactive endocannabinoid, 2-arachidonoyl glycerol (2-AG)"],"prefix":"10.1007","author":[{"given":"R. M.","family":"McCarron","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Shohami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Panikashvili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Golech","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Strasser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Mechoulam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Spatz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"59_CR1","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/0006-8993(95)01492-6","volume":"717","author":"E Beit-Yannai","year":"1996","unstructured":"Beit-Yannai E, Zhang R, Trembovler V, Samuni A, Shohami E (1996) Cerebroprotective effect of stable nitroxide radicals in closed head injury in the rat. Brain Res 717: 22\u201328","journal-title":"Brain Res"},{"key":"59_CR2","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1089\/neu.1996.13.755","volume":"13","author":"Y Chen","year":"1996","unstructured":"Chen Y, Constantini S, Trembovler V, Weinstock M, Shohami EJ (1996) An experimental model of closed head injury in mice: pathophysiology, histopathology, and cognitive deficits. J Neurotrauma 13: 557\u2013568","journal-title":"J Neurotrauma"},{"key":"59_CR3","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1161\/01.RES.87.4.323","volume":"87","author":"Y Chen","year":"2000","unstructured":"Chen Y, McCarron RM, Azzam N, Reutzler C, Lenz FA, Spatz M (2000) Human brain capillary endothelium: 2-Arachidonoglycerol (Endocannabinoid) interacts with Endothelin-1. Circ Res 87: 323\u2013327","journal-title":"Circ Res"},{"key":"59_CR4","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/S0005-2760(98)00042-3","volume":"1392","author":"V Marzo Di","year":"1998","unstructured":"Di Marzo V (1998) Endocannabinoids\u2019 and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance. Biochim Biophys Acta 1392: 153\u2013175","journal-title":"Biochim Biophys Acta"},{"key":"59_CR5","doi-asserted-by":"publisher","first-page":"R5","DOI":"10.1016\/S0014-2999(00)00653-1","volume":"406","author":"R Gallily","year":"2000","unstructured":"Gallily R, Breuer A, Mechoulam R (2000) 2-Arachidonylglycerol, an endogenous cannabinoid, inhibits tumor necrosis factor-alpha production in murine macrophages, and in mice. Eur J Pharmacol 406: R5\u20137","journal-title":"Eur J Pharmacol"},{"key":"59_CR6","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1091\/mbc.12.1.85","volume":"12","author":"M Gonzales","year":"2001","unstructured":"Gonzales M, Weksler B, Tsuruta D, Goldman RD, Yoon KJ, Hopkinson SB, Flitney FW, Jones JCR (2001) Structure and function of a vimentin-associated matrix adhesion in endothelial cells. Mol Biol Cell 12: 85\u2013100","journal-title":"Mol Biol Cell"},{"key":"59_CR7","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1089\/ars.1999.1.2-221","volume":"1","author":"AI Haj-Yehia","year":"1999","unstructured":"Haj-Yehia AI, NassarT, Assaf P, Nassar H, Anggard EE (1999) Effects of the superoxide dismutase-mimic compound TEMPOL on oxidant stress-mediated endothelial dysfunction. Antioxid Redox Signal 1: 221\u2013232","journal-title":"Antioxid Redox Signal"},{"key":"59_CR8","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1089\/neu.2000.17.871","volume":"17","author":"A Lewan","year":"2000","unstructured":"Lewan A, Matz P, Chan PH (2000) Free radical pathway in CNS injury. J Neurotrauma 17: 871\u2013890","journal-title":"J Neurotrauma"},{"key":"59_CR9","doi-asserted-by":"crossref","first-page":"C719","DOI":"10.1152\/ajpcell.2001.280.4.C719","volume":"280","author":"H Lum","year":"2001","unstructured":"Lum H, Roebuck KA (2001) Oxidant stress and endothelial cell dysfunction. Am J Physiol 280: C719\u2013C741","journal-title":"Am J Physiol"},{"key":"59_CR10","doi-asserted-by":"crossref","unstructured":"McCarron RM, Uematsu S, Merkel N, Long D, Bembry J, Spatz M (1990) The role of arachidonic acid and oxygen radicals on cerebromicrovascular endothelial permeability. Acta Neurochir (Wien) [Suppl] 51: 61\u201364","DOI":"10.1007\/978-3-7091-9115-6_21"},{"key":"59_CR11","first-page":"RE5","volume":"129","author":"R Mechoulam","year":"2002","unstructured":"Mechoulam R, Spatz M, Shohami E (2002) Endocannabinoids and neuroprotection. Sci STKE 129: RE5","journal-title":"Sci STKE"},{"key":"59_CR12","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1038\/35097089","volume":"413","author":"D Panikashvili","year":"2001","unstructured":"Panikashvili D, Simeonidou C, Ben-Shabat S, Hanus L, Breuer A, Mechoulam R, Shohami E (2001) An endogenous cannabinoid (2-AG) is neuroprotective after brain injury. Nature 413: 527\u2013531","journal-title":"Nature"},{"key":"59_CR13","doi-asserted-by":"publisher","first-page":"646","DOI":"10.3171\/jns.2000.92.4.0646","volume":"92","author":"R Rak","year":"2000","unstructured":"Rak R, Chao DL, Pluta RM, Mitchell JB, Oldfield EH, Watson JC (2000) Neuroprotection by the stable nitroxide Tempol during reperfusion in a rat model of transient focal ischemia. J Neurosurg 92: 646\u2013651","journal-title":"J Neurosurg"},{"key":"59_CR14","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/S0165-6147(97)01161-9","volume":"19","author":"MD Randall","year":"1998","unstructured":"Randall MD, Kendall DA (1998) Endocannabinoids: a new class of vasoactive substances. Trends Pharmacol Sci 19: 55\u201358","journal-title":"Trends Pharmacol Sci"},{"key":"59_CR15","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1042\/bj2750789","volume":"275","author":"KR Rogers","year":"1991","unstructured":"Rogers KR, Morris CJ, Blake DR (1991) Oxidation of thiol in the vimentin cytoskeleton. Biochem J 275: 789\u2013791","journal-title":"Biochem J"},{"key":"59_CR16","doi-asserted-by":"crossref","first-page":"C231","DOI":"10.1152\/ajpcell.1997.272.1.C231","volume":"272","author":"M Spatz","year":"1997","unstructured":"Spatz M, Kawai N, Merkel N, Bembry J, McCarron RM (1997) Functional properties of cultured endothelial cells derived from large microvessels of human brain. Am J Physiol 272: C231\u2013C239","journal-title":"Am J Physiol"},{"key":"59_CR17","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1006\/bbrc.1998.8187","volume":"243","author":"T Sugiura","year":"1998","unstructured":"Sugiura T, Kodaka T, Nakane S, Kishimoto S, Kondo S, Waku K (1998) Detection of an endogenous cannabimimetic molecule, 2-arachidonoylglycerol, and cannabinoid CB1 receptor mRNA in human vascular cells: is 2-arachidonoylglycerol a possible vasomodulator? Biochem Biophys Res Commun 243: 838\u2013843","journal-title":"Biochem Biophys Res Commun"},{"key":"59_CR18","first-page":"202","volume":"70","author":"Y Yasuma","year":"1997","unstructured":"Yasuma Y, Strasser A, Ruetzel C, McCarron RM, Spatz M (1997) The effect of nitric oxide inhibition on ischemic brain edema. Acta Neurochir (Wien) [Suppl] 70: 202\u2013205","journal-title":"Acta Neurochir (Wien) [Suppl]"}],"container-title":["Brain Edema XII"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-7091-0651-8_59","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,31]],"date-time":"2019-03-31T02:58:59Z","timestamp":1554001139000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-7091-0651-8_59"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003]]},"ISBN":["9783709172209","9783709106518"],"references-count":18,"URL":"https:\/\/doi.org\/10.1007\/978-3-7091-0651-8_59","relation":{},"subject":[],"published":{"date-parts":[[2003]]}}}