{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,8]],"date-time":"2024-09-08T12:05:35Z","timestamp":1725797135559},"publisher-location":"Vienna","reference-count":22,"publisher":"Springer Vienna","isbn-type":[{"type":"print","value":"9783211835296"},{"type":"electronic","value":"9783709163085"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000]]},"DOI":"10.1007\/978-3-7091-6308-5_15","type":"book-chapter","created":{"date-parts":[[2014,7,14]],"date-time":"2014-07-14T22:30:14Z","timestamp":1405377014000},"page":"161-171","source":"Crossref","is-referenced-by-count":5,"title":["Putting prions into focus: application of single molecule detection to the diagnosis of prion diseases"],"prefix":"10.1007","author":[{"given":"A.","family":"Giese","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Bieschke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Eigen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. A.","family":"Kretzschmar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"15_CR1","doi-asserted-by":"crossref","first-page":"7859","DOI":"10.1128\/JVI.68.12.7859-7868.1994","volume":"68","author":"RA Bessen","year":"1994","unstructured":"Bessen RA, Marsh RF (1994) Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy. J Virol 68: 7859\u20137868","journal-title":"J Virol"},{"key":"15_CR2","doi-asserted-by":"publisher","first-page":"5468","DOI":"10.1073\/pnas.97.10.5468","volume":"97","author":"J Bieschke","year":"2000","unstructured":"Bieschke J, Giese A, Schulz-Schaeffef W, Zerr I, Poser S, Eigen M, Kretzschmar HA (2000) Ultra-sensitive detection of pathological prion protein aggregates by dual-color scanning for intensely fluorescent targets. Proc Natl Acad Sci USA 97: 5468\u20135473","journal-title":"Proc Natl Acad Sci USA"},{"key":"15_CR3","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1002\/ana.410350504","volume":"35","author":"P Brown","year":"1994","unstructured":"Brown P, Gibbs CJ Jr, Rodgers-Johnson P, Asher DM, Sulima MP, Bacote A, Goldfarb LG, Gajdusek DC (1994) Human spongiform encephalopathy: the National Institutes of Health series of 300 cases of experimentally transmitted disease. Ann Neurol 35: 513\u2013529","journal-title":"Ann Neurol"},{"key":"15_CR4","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1038\/39057","volume":"389","author":"ME Bruce","year":"1997","unstructured":"Bruce ME, Will RG, Ironside JW, McConnell I, Drummond P, Suttie A, McCardle L, Chree A, Hope J, Birkett C, Cousens S, Fraser H, Bostock CJ (1997) Transmissions to mice indicate that new variant CJD is caused by the BSE agent. Nature 389: 498\u2013501","journal-title":"Nature"},{"key":"15_CR5","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1016\/1074-5521(95)90087-X","volume":"2","author":"B Caughey","year":"1995","unstructured":"Caughey B, Kocisko DA, Raymond GJ, Lansbury PT Jr (1995) Aggregates of scrapie-associated prion prptein induce the cell-free conversion of protease-sensitive prion protein to the protease-resistant state. Chem Biol 2: 807\u2013817","journal-title":"Chem Biol"},{"key":"15_CR6","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1016\/S0006-3495(99)76912-2","volume":"77","author":"Y Chen","year":"1999","unstructured":"Chen Y, Muller JD, So PT, Gratton E (1999) The photon counting histogram in fluorescence fluctuation spectroscopy. Biophys J 77: 553\u2013567","journal-title":"Biophys J"},{"key":"15_CR7","doi-asserted-by":"publisher","first-page":"5740","DOI":"10.1073\/pnas.91.13.5740","volume":"91","author":"M Eigen","year":"1994","unstructured":"Eigen M, Rigler R (1994) Sorting single molecules: application to diagnostics and evolutionary biotechnology. Proc Natl Acad Sci USA 91: 5740\u20135747","journal-title":"Proc Natl Acad Sci USA"},{"key":"15_CR8","doi-asserted-by":"publisher","first-page":"l","DOI":"10.1016\/S0301-4622(96)02250-8","volume":"63","author":"M Eigen","year":"1996","unstructured":"Eigen M (1996) Prionics or the kinetic basis of prion diseases. Biophys Chem 63: Al\u201318","journal-title":"Biophys Chem"},{"key":"15_CR9","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.1016\/S0140-6736(05)60744-1","volume":"352","author":"AC Ghani","year":"1998","unstructured":"Ghani AC, Ferguson NM, Donnelly CA, Hagenaars TJ, Anderson RM (1998) Estimation of the number of people incubating variant CJD. Lancet 352: 1353\u20131354","journal-title":"Lancet"},{"key":"15_CR10","doi-asserted-by":"crossref","first-page":"3688","DOI":"10.1128\/JVI.61.12.3688-3693.1987","volume":"61","author":"RJ Kascsak","year":"1987","unstructured":"Kascsak RJ, Rubenstein R, Merz PA, Tonna-DeMasi M, Fersko R, Carp RI, Wisniewski HM, Diringer H (1987) Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins. J Virol 61: 3688\u20133693","journal-title":"J Virol"},{"key":"15_CR11","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1007\/BF03401656","volume":"2","author":"S Krasemann","year":"1996","unstructured":"Krasemann S, Groschup MH, Harmeyer S, Hunsmann G, Bodemer W (1996) Generation of monoclonal antibodies against human prion proteins in PrP0\/0 mice. Mol Med 2: 725\u2013734","journal-title":"Mol Med"},{"key":"15_CR12","doi-asserted-by":"crossref","first-page":"4O6","DOI":"10.1007\/BF03402129","volume":"5","author":"T Kuczius","year":"1999","unstructured":"Kuczius T, Groschup MH (1999) Differences in proteinase K resistance and neuronal deposition of abnormal prion proteins characterize bovine spongiform encephalopathy (BSE) and scrapie strains. Mol Med 5: 4O6\u2013418","journal-title":"Mol Med"},{"key":"15_CR13","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/S0301-4622(99)00016-2","volume":"77","author":"J Masel","year":"1999","unstructured":"Masel J, Jansen VA, Nowak MA (1999) Quantifying the kinetic parameters of prion replication. Biophys Chem 77: 139\u2013152","journal-title":"Biophys Chem"},{"key":"15_CR14","doi-asserted-by":"publisher","first-page":"2310","DOI":"10.1073\/pnas.83.8.2310","volume":"83","author":"RK Meyer","year":"1986","unstructured":"Meyer RK, McKinley MP, Bowman KA, Braunfeld MB, Barry RA, Prusiner SB (1986) Separation and properties of cellular and scrapie prion proteins. Proc Natl Acad Sci USA 83: 2310\u20132314","journal-title":"Proc Natl Acad Sci USA"},{"key":"15_CR15","doi-asserted-by":"publisher","first-page":"10962","DOI":"10.1073\/pnas.90.23.10962","volume":"90","author":"K-M Pan","year":"1993","unstructured":"Pan K-M, Baldwin M, Nguyen J, Gasset M, Serban A, Groth D, Mehlhorn I, Huang Z, Fletterick RJ, Cohen FE, Prusiner SB (1993) Conversion of \u03b1-helices into \u00df-sheets features in the formation of the scrapie prion proteins. Proc Natl Acad Sci USA 90: 10962\u201310966","journal-title":"Proc Natl Acad Sci USA"},{"key":"15_CR16","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1038\/nm0798-832","volume":"4","author":"M Pitschke","year":"1998","unstructured":"Pitschke M, Prior R, Haupt M, Riesner D (1998) Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer\u2019s patients by fluorescence correlation spectroscopy. Nature Med 4: 832\u2013834","journal-title":"Nature Med"},{"key":"15_CR17","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/0092-8674(83)90168-X","volume":"35","author":"SB Prusiner","year":"1983","unstructured":"Prusiner SB, McKinley MP, Bowman KA, Bolton DC, Bendheim PE, Groth DF, Glenner GG (1983) Scrapie prions aggregate to form amyloid-like birefringent rods. Cell 35: 349\u2013358","journal-title":"Cell"},{"key":"15_CR18","doi-asserted-by":"publisher","first-page":"13363","DOI":"10.1073\/pnas.95.23.13363","volume":"95","author":"SB Prusiner","year":"1998","unstructured":"Prusiner SB (1998) Prions. Proc Natl Acad Sci USA 95: 13363\u201313383","journal-title":"Proc Natl Acad Sci USA"},{"key":"15_CR19","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1007\/BF00185777","volume":"22","author":"R Rigler","year":"1993","unstructured":"Rigler R, Mets \u00dc, Widengren J, Kask P (1993) Fluorescence correlation spectroscopy with high count rate and low background: analysis of translational diffusion. Eur Biophys J 22: 169\u2013173","journal-title":"Eur Biophys J"},{"key":"15_CR20","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/S0301-4622(97)00061-6","volume":"66","author":"P Schw\u00fcle","year":"1997","unstructured":"Schw\u00fcle P, Bieschke J, Oehlenschl\u00e4ger F (1997) Kinetic investigations by fluorescence correlation spectroscopy: the analytical and diagnostic potential of diffusion studies. Biophys Chem 66: 211\u2013228","journal-title":"Biophys Chem"},{"key":"15_CR21","doi-asserted-by":"publisher","first-page":"1878","DOI":"10.1016\/S0006-3495(97)78833-7","volume":"72","author":"P Schw\u00fcle","year":"1997","unstructured":"Schw\u00fcle P, Meyer-Almes FJ, Rigler R (1997) Dual-color fluorescence cross-correlation spectroscopy for multicomponent diffusional analysis in solution. Biophys J 72: 1878\u20131886","journal-title":"Biophys J"},{"key":"15_CR22","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1016\/S0140-6736(96)91412-9","volume":"347","author":"RG Will","year":"1996","unstructured":"Will RG, Ironside JW, Zeidler M, Cousens SN, Estibeiro K, Alperovitch A, Poser S, Pocchiari M, Hofman A, Smith PG (1996) A new variant of Creutzfeldt-Jakob disease in the UK. Lancet 347: 921\u2013925","journal-title":"Lancet"}],"container-title":["Prion Diseases"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-3-7091-6308-5_15","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,22]],"date-time":"2020-08-22T07:56:30Z","timestamp":1598082990000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-3-7091-6308-5_15"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000]]},"ISBN":["9783211835296","9783709163085"],"references-count":22,"URL":"https:\/\/doi.org\/10.1007\/978-3-7091-6308-5_15","relation":{},"subject":[],"published":{"date-parts":[[2000]]}}}