{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T19:24:48Z","timestamp":1791055488181,"version":"4.1.0"},"publisher-location":"Dordrecht","reference-count":32,"publisher":"Springer Netherlands","isbn-type":[{"value":"9789048122585","type":"print"},{"value":"9789048122592","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009]]},"DOI":"10.1007\/978-90-481-2259-2_36","type":"book-chapter","created":{"date-parts":[[2009,4,20]],"date-time":"2009-04-20T08:18:50Z","timestamp":1240215530000},"page":"319-328","source":"Crossref","is-referenced-by-count":15,"title":["Effects of Intermittent Hypoxia on Blood Gases Plasma Catecholamine and Blood Pressure"],"prefix":"10.1007","author":[{"given":"M.C.","family":"Gonz\u00e1lez-Mart\u00edn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Vega-Agapito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Prieto-Lloret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.T.","family":"Agapito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Casta\u00f1eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Gonzalez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"36_CR1","doi-asserted-by":"publisher","first-page":"H434","DOI":"10.1152\/ajpheart.91477.2007","volume":"295","author":"KJ. Allahdadi","year":"2008","unstructured":"Allahdadi KJ, Cherng TW, Pai H, Silva AQ, Walker BR, Nelin LD, Kanagy NL. 2008. Endothelin type A receptor antagonist normalizes blood pressure in rats exposed to eucapnic intermittent hypoxia. Am J Physiol Heart Circ Physiol. 295:H434\u201340.","journal-title":"Am J Physiol Heart Circ Physiol."},{"key":"36_CR2","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1097\/00063198-200211000-00003","volume":"8","author":"CD. Boethel","year":"2002","unstructured":"Boethel CD. 2002. Sleep and the endocrine system: new associations to old diseases. Curr Opin Pulm Med. 8:502\u20135.","journal-title":"Curr Opin Pulm Med."},{"key":"36_CR3","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1177\/1099800403257088","volume":"5","author":"ER. Chasens","year":"2003","unstructured":"Chasens ER, Weaver TE, Umlauf MG. 2003. Insulin resistance and obstructive sleep apnea: is increased sympathetic stimulation the link? Biol Res Nurs. 5:87\u201396.","journal-title":"Biol Res Nurs."},{"key":"36_CR4","doi-asserted-by":"publisher","first-page":"454","DOI":"10.2169\/internalmedicine.36.454","volume":"36","author":"K. Chin","year":"1997","unstructured":"Chin K, Hirai M, Kuriyama T, Fukui M, Kuno K, Sagawa Y, Ohi M. 1997. Changes in the arterial PCO2 during a single night\u2019s sleep in patients with obstructive sleep apnea. Intern Med. 36:454\u201360.","journal-title":"Intern Med."},{"key":"36_CR5","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1093\/sleep\/19.suppl_10.160","volume":"19","author":"JA. Dempsey","year":"1996","unstructured":"Dempsey JA, Smith CA, Harms CA, Chow C, Saupe KW. 1996. Sleep-induced breathing instability. University of Wisconsin-Madison Sleep and respiration Research Group. Sleep. 19:236\u201347.","journal-title":"Sleep."},{"key":"36_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1172\/JCI119119","volume":"99","author":"JA. Dempsey","year":"1997","unstructured":"Dempsey JA. 1997. Sleep apnea causes daytime hypertension. J Clin Invest. 99:1\u20132.","journal-title":"J Clin Invest."},{"key":"36_CR7","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1016\/S0030-6665(02)00178-0","volume":"36","author":"DW. Eisele","year":"2003","unstructured":"Eisele DW, Schwartz AR, Smith PL. 2003. Tongue neuromuscular and direct hypoglossal nerve stimulation for obstructive sleep apnea. Otolaryngol Clin North Am. 36:501\u201310.","journal-title":"Otolaryngol Clin North Am."},{"key":"36_CR8","doi-asserted-by":"crossref","unstructured":"Fletcher EC, Lesske J, Behm R, Miller III, CC, Staus H, Unger T. 1992. Carotid chemoreceptors, systemic blood pressure and chronic episodic hypoxia mimicking sleep apnea. J. Appl. Physiol. 72:1978\u20131984.","DOI":"10.1152\/jappl.1992.72.5.1978"},{"key":"36_CR9","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1113\/jphysiol.2005.091462","volume":"567","author":"GE. Foster","year":"2005","unstructured":"Foster GE, McKenzie DC, Milsom WK, Sheel AW. 2005. Effects of two protocols of intermittent hypoxia on human ventilatory, cardiovascular and cerebral responses to hypoxia. J Physiol Sep 1;567:689\u201399.","journal-title":"J Physiol"},{"key":"36_CR10","doi-asserted-by":"crossref","first-page":"R1977","DOI":"10.1152\/ajpregu.00622.2006","volume":"292","author":"Q. Fu","year":"2007","unstructured":"Fu Q, Townsend NE, Shiller SM, Martini ER, Okazaki K, Shibata S, Truijens MJ, Rodr\u00edguez FA, Gore CJ, Stray-Gundersen J, Levine BD. 2007. Intermittent hypobaric hypoxia exposure does not cause sustained alterations in autonomic control of blood pressure in young athletes. Am J Physiol Regul Integr Comp Physiol. 292:R1977\u201384.","journal-title":"Am J Physiol Regul Integr Comp Physiol."},{"key":"36_CR11","doi-asserted-by":"crossref","first-page":"2656","DOI":"10.1152\/jappl.1994.76.6.2656","volume":"76","author":"EB. Gauda","year":"1994","unstructured":"Gauda EB, Carroll TP, Schwartz AR, Smith PL, Fitzgerald RS. 1994. Mechano- and chemoreceptor modulation of respiratory muscles in response to upper airway negative pressure. J Appl Physiol. 76:2656\u201362.","journal-title":"J Appl Physiol."},{"key":"36_CR12","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1124\/jpet.103.049270","volume":"305","author":"DS. Goldstein","year":"2003","unstructured":"Goldstein DS, Eisenhofer G, Kopin IJ. 2003. Sources and significance of plasma levels of catechols and their metabolites in humans. J Pharmacol Exp Ther. 305:800\u201311.","journal-title":"J Pharmacol Exp Ther."},{"key":"36_CR13","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1152\/physrev.1994.74.4.829","volume":"74","author":"C. Gonzalez","year":"1994","unstructured":"Gonzalez C, Almaraz L, Obeso A, Rigual R. 1994. Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol Rev.74:829\u201398.","journal-title":"Physiol Rev."},{"key":"36_CR14","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.1161\/01.HYP.0000175477.33816.f3","volume":"46","author":"C. Hinojosa-Laborde","year":"2005","unstructured":"Hinojosa-Laborde C, Mifflin SW. 2005. Sex differences in blood pressure response to intermittent hypoxia in rats. Hypertension. 46:1016\u201321.","journal-title":"Hypertension."},{"key":"36_CR15","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1161\/01.HYP.37.2.511","volume":"37","author":"NL. Kanagy","year":"2001","unstructured":"Kanagy NL, Walker BR, Nelin LD. 2001 Role of endothelin in intermittent hypoxia-induced hypertension. Hypertension.37:511\u20135","journal-title":"Hypertension."},{"key":"36_CR16","first-page":"91","volume":"13","author":"L. Kubin","year":"1998","unstructured":"Kubin L, Davies RO, Pack AI. 1998. Control of upper airway motoneurons during REM Sleep. News Physiol Sci. Apr;13:91\u201397.","journal-title":"News Physiol Sci."},{"key":"36_CR17","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1113\/jphysiol.2006.112524","volume":"575","author":"GK. Kumar","year":"2006","unstructured":"Kumar GK, Rai V, Sharma SD, Ramakrishnan DP, Peng YJ, Souvannakitti D, Prabhakar NR. 2006. Chronic intermittent hypoxia induces hypoxia-evoked catecholamine efflux in adult rat adrenal medulla via oxidative stress. J Physiol. 575:229\u201339.","journal-title":"J Physiol."},{"key":"36_CR18","doi-asserted-by":"publisher","first-page":"1974","DOI":"10.1152\/japplphysiol.01051.2005","volume":"100","author":"CJ. Lai","year":"2006","unstructured":"Lai CJ, Yang CC, Hsu YY, Lin YN, Kuo TB. 2006. Enhanced sympathetic outflow and decreased baroreflex sensitivity are associated with intermittent hypoxia-induced systemic hypertension in conscious rats. J Appl Physiol. 100:1974\u201382.","journal-title":"J Appl Physiol."},{"issue":"9","key":"36_CR19","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1016\/S0735-1097(03)00184-0","volume":"41","author":"JD. Lattimore","year":"2003","unstructured":"Lattimore JD, Celermajer DS, Wilcox I. 2003. Obstructive sleep apnea and cardiovascular disease. J Am Coll Cardiol. 41(9):1429\u201337.","journal-title":"J Am Coll Cardiol."},{"key":"36_CR20","doi-asserted-by":"publisher","first-page":"H997","DOI":"10.1152\/ajpheart.01124.2006","volume":"293","author":"M. Lin","year":"2007","unstructured":"Lin M, Liu R, Gozal D, Wead WB, Chapleau MW, Wurster R, Cheng ZJ. 2007. Chronic intermittent hypoxia impairs baroreflex control of heart rate but enhances heart rate responses to vagal efferent stimulation in anesthetized mice. Am J Physiol Heart Circ Physiol. 293:H997\u20131006.","journal-title":"Am J Physiol Heart Circ Physiol."},{"issue":"26","key":"36_CR21","doi-asserted-by":"publisher","first-page":"2123","DOI":"10.1016\/0024-3205(93)90727-K","volume":"52","author":"KJ. Morrison","year":"1993","unstructured":"Morrison KJ, Gao Y, Vanhoutte PM. 1993. Beta-adrenoceptors and the epithelial layer in airways . Life Sci. 52(26):2123\u201330.","journal-title":". Life Sci."},{"key":"36_CR22","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/0034-5687(93)90066-J","volume":"93","author":"Y. Oku","year":"1993","unstructured":"Oku Y, Bruce EN, Richmonds CR, Hudgel DW. 1993. The carotid body in the motorneuron response to protriptyline. Respir Physiol. 93:41\u20139.","journal-title":"Respir Physiol."},{"key":"36_CR23","doi-asserted-by":"publisher","first-page":"10073","DOI":"10.1073\/pnas.1734109100","volume":"100","author":"YJ. Peng","year":"2003","unstructured":"Peng YJ, Overholt JL, Kline D, Kumar GK, Prabhakar NR. 2003. Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneas. Proc Natl Acad Sci USA. 100:10073\u20138.","journal-title":"Proc Natl Acad Sci USA."},{"key":"36_CR24","doi-asserted-by":"publisher","first-page":"1236","DOI":"10.1152\/japplphysiol.00820.2003","volume":"96","author":"YJ. Peng","year":"2004","unstructured":"Peng YJ, Prabhakar NR. 2004. Effect of two paradigms of chronic intermittent hypoxia on carotid body sensory activity. J Appl Physiol. 96:1236\u201342.","journal-title":"J Appl Physiol."},{"key":"36_CR25","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1111\/j.1440-1681.2005.04209.x","volume":"32","author":"NR. Prabhakar","year":"2005","unstructured":"Prabhakar NR, Peng YJ, Jacono FJ, Kumar GK, Dick TE. 2005. Cardiovascular alterations by chronic intermittent hypoxia: importance of carotid body chemoreflexes. Clin Exp Pharmacol Physiol. 32, 447\u2013449.","journal-title":"Clin Exp Pharmacol Physiol."},{"key":"36_CR26","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/S0378-4347(99)00213-3","volume":"730","author":"MA. Raggi","year":"1999","unstructured":"Raggi MA, Sabbioni C, Casamenti G, Gerra G, Calonghi N, Masotti L. 1999. Determination of catecholamines in human plasma by high-performance liquid chromatography with electrochemical detection. J Chromatogr B Biomed Sci Appl. 730:201\u201311.","journal-title":"J Chromatogr B Biomed Sci Appl."},{"key":"36_CR27","doi-asserted-by":"publisher","first-page":"2440","DOI":"10.1152\/japplphysiol.00772.2005","volume":"99","author":"CM. Ryan","year":"2005","unstructured":"Ryan CM, Bradley TD. 2005. Pathogenesis of obstructive sleep apnea . J Appl Physiol. 99:2440\u201350.","journal-title":"J Appl Physiol"},{"key":"36_CR28","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/S0034-5687(00)00126-2","volume":"121","author":"AL. Sica","year":"2000","unstructured":"Sica AL, Greenberg HE, Ruggiero DA, Scharf SM. 2000. Chronic-intermittent hypoxia: a model of sympathetic activation in the rat. Respir Physiol. 121:173\u201384.","journal-title":"Respir Physiol."},{"key":"36_CR29","doi-asserted-by":"publisher","first-page":"H2971","DOI":"10.1152\/ajpheart.00219.2007","volume":"293","author":"CM. Troncoso Brindeiro","year":"2007","unstructured":"Troncoso Brindeiro CM, da Silva AQ, Allahdadi KJ, Youngblood V, Kanagy NL. 2007. Reactive oxygen species contribute to sleep apnea-induced hypertension in rats. Am J Physiol Heart Circ Physiol. 293:H2971\u20136.","journal-title":"Am J Physiol Heart Circ Physiol."},{"key":"36_CR30","first-page":"2073","volume-title":"The Lung: Scientific Foundations","author":"E. Lunteren Van","year":"1997","unstructured":"Van Lunteren E. 1997. Upper airway effects on breathing. In The Lung: Scientific Foundations, Crystal RG, West JB, Weibel ER, Barnes PJ, eds. Philadelphia, Lippincott-Raven. pp.2073\u20132084."},{"key":"36_CR31","doi-asserted-by":"publisher","first-page":"2034","DOI":"10.1056\/NEJMoa043104","volume":"353","author":"HK. Yaggi","year":"2005","unstructured":"Yaggi HK, Concato J, Kernan WN, Lichtman JH, Brass LM, Mohsenin V. 2005. Obstructive sleep apnea as a risk factor for stroke and death. N Engl J Med. 353:2034\u201341.","journal-title":"N Engl J Med."},{"key":"36_CR32","doi-asserted-by":"publisher","first-page":"3253","DOI":"10.1113\/jphysiol.2008.154187","volume":"586","author":"DB. Zoccal","year":"2008","unstructured":"Zoccal DB, Simms AE, Bonagamba LG, Braga VA, Pickering AE, Paton JF, Machado BH. 2008. Increased sympathetic outflow in juvenile rats submitted to chronic intermittent hypoxia correlates with enhanced expiratory activity. J Physiol. 586:3253\u201365.","journal-title":"J Physiol."}],"container-title":["Advances in Experimental Medicine and Biology","Arterial Chemoreceptors"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-90-481-2259-2_36.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T06:52:39Z","timestamp":1606287159000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-90-481-2259-2_36"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"ISBN":["9789048122585","9789048122592"],"references-count":32,"URL":"https:\/\/doi.org\/10.1007\/978-90-481-2259-2_36","relation":{},"ISSN":["0065-2598"],"issn-type":[{"value":"0065-2598","type":"print"}],"subject":[],"published":{"date-parts":[[2009]]}}}