{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T09:22:06Z","timestamp":1789809726294,"version":"4.0.1"},"publisher-location":"Dordrecht","reference-count":21,"publisher":"Springer Netherlands","isbn-type":[{"value":"9789048122585","type":"print"},{"value":"9789048122592","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009]]},"DOI":"10.1007\/978-90-481-2259-2_38","type":"book-chapter","created":{"date-parts":[[2009,4,20]],"date-time":"2009-04-20T08:18:50Z","timestamp":1240215530000},"page":"337-344","source":"Crossref","is-referenced-by-count":8,"title":["Ventilatory Drive Is Enhanced in Male and Female Rats Following Chronic Intermittent Hypoxia"],"prefix":"10.1007","author":[{"given":"D.","family":"Edge","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.R.","family":"Skelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Bradford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.D.","family":"O\u2019Halloran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"38_CR1","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/S1569-9048(03)00086-7","volume":"136","author":"M. Behan","year":"2003","unstructured":"Behan, M., Zabka, A.G., Thomas, C.F., Mitchell, G.S. 2003, Sex steroid hormones and the neural control of breathing, Respir Physiol Neurobiol 136: 249\u201363.","journal-title":"Respir Physiol Neurobiol"},{"key":"38_CR2","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.resp.2005.04.001","volume":"147","author":"A. Bradford","year":"2005","unstructured":"Bradford, A., McGuire, M., O\u2019Halloran, K.D. 2005, Does episodic hypoxia affect upper airway dilator muscle function? Implications for the pathophysiology of obstructive sleep apnoea, Respir Physiol Neurobiol 147: 223\u201334.","journal-title":"Respir Physiol Neurobiol"},{"key":"38_CR3","doi-asserted-by":"publisher","first-page":"458","DOI":"10.1007\/978-0-387-73693-8_80","volume":"605","author":"M. Dunleavy","year":"2008","unstructured":"Dunleavy, M., Bradford, A., O\u2019Halloran, K.D. 2008, Oxidative stress impairs upper airway muscle endurance in an animal model of sleep-disordered breathing, Adv Exp Med Biol 605: 458\u201362.","journal-title":"Adv Exp Med Biol"},{"key":"38_CR4","doi-asserted-by":"crossref","first-page":"R1356","DOI":"10.1152\/ajpregu.00884.2007","volume":"294","author":"C. Julien","year":"2008","unstructured":"Julien, C., Bairam, A., Joseph, V. 2008, Chronic intermittent hypoxia reduces ventilatory long-term facilitation and enhances apnea frequency in newborn rats, Am J Physiol Regul Integr Comp Physiol 294: R1356\u201366.","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"38_CR5","doi-asserted-by":"publisher","first-page":"1942","DOI":"10.1152\/japplphysiol.00735.2007","volume":"103","author":"K. Katayama","year":"2007","unstructured":"Katayama, K., Smith, C.A., Henderson, K.S., Dempsey, J.A. 2007, Chronic intermittent hypoxia increases the CO2 reserve in sleeping dogs, J Appl Physiol 103: 1942\u20139.","journal-title":"J Appl Physiol"},{"key":"38_CR6","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1152\/japplphysiol.00044.2003","volume":"95","author":"M. McGuire","year":"2003","unstructured":"McGuire, M., Zhang, Y., White, D.P., Ling, L. 2003, Chronic intermittent hypoxia enhances ventilatory long-term facilitation in awake rats, J Appl Physiol 95: 1499\u2013508.","journal-title":"J Appl Physiol"},{"key":"38_CR7","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1378\/chest.122.1.269","volume":"122","author":"K.D. O\u2019Halloran","year":"2002","unstructured":"O\u2019Halloran, K.D., McGuire, M., O\u2019Hare, T., Bradford, A. 2002, Chronic intermittent asphyxia impairs rat upper airway muscle responses to acute hypoxia and asphyxia, Chest 122: 269\u201375.","journal-title":"Chest"},{"key":"38_CR8","unstructured":"O\u2019Halloran, K.D., McGuire M, Bradford, A. 2007, Respiratory plasticity following chronic intermittent hypercapnic hypoxia in conscious rats. In Proceedings of the Joint Meeting of the Slovak Physiological Society, the Physiological Society and the Federation of European Physiological Societies, ed. V Strbak, Medimond S. r. l., Italy, pp.99\u2013103."},{"key":"38_CR9","doi-asserted-by":"publisher","first-page":"1287","DOI":"10.1152\/japplphysiol.00644.2007","volume":"104","author":"A. Pawar","year":"2008","unstructured":"Pawar, A., Peng, Y.J., Jacono, F.J., Prabhakar, N.R. 2008, Comparative analysis of neonatal and adult rat carotid body responses to chronic intermittent hypoxia, J Appl Physiol 104: 1287\u201394.","journal-title":"J Appl Physiol"},{"key":"38_CR10","doi-asserted-by":"publisher","first-page":"10073","DOI":"10.1073\/pnas.1734109100","volume":"100","author":"Y.J. Peng","year":"2003","unstructured":"Peng, Y.J., Overholt, J.L., Kline, D., Kumar, G.K., Prabhakar, N.R. 2003, Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneas, Proc Natl Acad Sci USA 100: 10073\u20138.","journal-title":"Proc Natl Acad Sci USA"},{"key":"38_CR11","doi-asserted-by":"publisher","first-page":"2020","DOI":"10.1152\/japplphysiol.00876.2003","volume":"97","author":"Y.J. Peng","year":"2004","unstructured":"Peng, Y.J., Rennison, J., Prabhakar, N.R. 2004, Intermittent hypoxia augments carotid body and ventilatory response to hypoxia in neonatal rat pups, J Appl Physiol 97: 2020\u20135.","journal-title":"J Appl Physiol"},{"key":"38_CR12","doi-asserted-by":"crossref","first-page":"R372","DOI":"10.1152\/ajpregu.00038.2007","volume":"293","author":"A.D. Ray","year":"2007","unstructured":"Ray, A.D., Magalang, U.J., Michlin, C.P., Ogasa, T., Krasney, J.A., Gosselin, L.E., Farkas, G.A. 2007, Intermittent hypoxia reduces upper airway stability in lean but not obese Zucker rats, Am J Physiol Regul Integr Comp Physiol 293: R372\u20138.","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"38_CR13","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1113\/jphysiol.2004.072033","volume":"560","author":"S. Rey","year":"2004","unstructured":"Rey, S., Del Rio, R., Alcayaga, J., Iturriaga, R. 2004, Chronic intermittent hypoxia enhances cat chemosensory and ventilatory responses to hypoxia, J Physiol 560: 577\u201386.","journal-title":"J Physiol"},{"key":"38_CR14","doi-asserted-by":"crossref","first-page":"R369","DOI":"10.1152\/ajpregu.00128.2004","volume":"287","author":"S.R. Reeves","year":"2004","unstructured":"Reeves, S.R., Gozal, D. 2004, Platelet-activating factor receptor modulates respiratory adaptation to long-term intermittent hypoxia in mice, Am J Physiol Regul Integr Comp Physiol 287: R369\u201374.","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"38_CR15","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.resp.2005.03.018","volume":"150","author":"S.R. Reeves","year":"2006","unstructured":"Reeves S.R., Gozal, D. 2006, Changes in ventilatory adaptations associated with long-term intermittent hypoxia across the age spectrum in the rat, Respir Physiol Neurobiol 150:135\u201343.","journal-title":"Respir Physiol Neurobiol"},{"key":"38_CR16","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1152\/japplphysiol.00759.2002","volume":"95","author":"S.R. Reeves","year":"2003","unstructured":"Reeves S.R., Gozal E., Guo S.Z., Sachleben, L.R. Jr, Brittian K.R., Lipton A.J., Gozal D. 2003, Effect of long-term intermittent and sustained hypoxia on hypoxic ventilatory and metabolic responses in the adult rat. J Appl Physiol. 95: 1767\u201374.","journal-title":"J Appl Physiol."},{"key":"38_CR17","doi-asserted-by":"crossref","unstructured":"Reeves, S.R., Guo, S.Z., Brittain K.R., Row, B.W., Gozal, D. 2006a, Anatomical changes in selected cardio-respiratory brainstem nuclei following early post-natal chronic intermittent hypoxia, Neurosci Lett 402: 233\u20137.","DOI":"10.1016\/j.neulet.2006.04.013"},{"key":"38_CR18","doi-asserted-by":"crossref","unstructured":"Reeves, S.R., Mitchell, G.S., Gozal, D. 2006b, Early postnatal chronic intermittent hypoxia modifies hypoxic respiratory responses and long-term phrenic facilitation in adult rats, Am J Physiol Regul Integr Comp Physiol 290: R1664\u201371.","DOI":"10.1152\/ajpregu.00851.2005"},{"key":"38_CR19","unstructured":"Skelly, J.R., Bradford A., O\u2019Halloran, K.D. 2008, Tempol, a SOD-mimetic, improves muscle function in a rat model of sleep apnoea, Proc Physiol Soc, in press."},{"key":"38_CR20","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1164\/rccm.200403-261OC","volume":"170","author":"S.C. Veasey","year":"2004","unstructured":"Veasey, S.C., Zhan, G., Fenik, P., Pratico, D. 2004, Long-term intermittent hypoxia: reduced excitatory hypoglossal nerve output, Am J Respir Crit Care Med 170: 665\u201372.","journal-title":"Am J Respir Crit Care Med"},{"key":"38_CR21","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1152\/jappl.2001.90.3.1065","volume":"90","author":"K.A. Waters","year":"2001","unstructured":"Waters, K.A. and Tinworth, K.D. 2001, Depression of ventilatory responses after daily, cyclic hypercapnic hypoxia in piglets, J Appl Physiol 90: 1065\u201373.","journal-title":"J Appl Physiol"}],"container-title":["Advances in Experimental Medicine and Biology","Arterial Chemoreceptors"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/978-90-481-2259-2_38.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T06:52:40Z","timestamp":1606287160000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/978-90-481-2259-2_38"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009]]},"ISBN":["9789048122585","9789048122592"],"references-count":21,"URL":"https:\/\/doi.org\/10.1007\/978-90-481-2259-2_38","relation":{},"ISSN":["0065-2598"],"issn-type":[{"value":"0065-2598","type":"print"}],"subject":[],"published":{"date-parts":[[2009]]}}}