{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T00:15:02Z","timestamp":1743120902806,"version":"3.40.3"},"publisher-location":"Dordrecht","reference-count":35,"publisher":"Springer Netherlands","isbn-type":[{"type":"print","value":"9789401771962"},{"type":"electronic","value":"9789401771979"}],"license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2015]]},"DOI":"10.1007\/978-94-017-7197-9_3","type":"book-chapter","created":{"date-parts":[[2015,7,28]],"date-time":"2015-07-28T08:47:24Z","timestamp":1438073244000},"page":"45-57","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Genetically Modified Mice for Studying TNAP Function"],"prefix":"10.1007","author":[{"given":"Sonoko","family":"Narisawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,7,29]]},"reference":[{"key":"3_CR1","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1002\/jbmr.110","volume":"25","author":"WN Addison","year":"2010","unstructured":"Addison WN, Masica DL, Gray JJ et al (2010) Phosphorylation-dependent inhibition of mineralization by osteopontin ASARM peptides is regulated by PHEX cleavage. J Bone Miner Res 25:695\u2013705","journal-title":"J Bone Miner Res"},{"key":"3_CR2","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1113\/expphysiol.2008.045864","volume":"94","author":"B Aigner","year":"2009","unstructured":"Aigner B, Rathkolb B, Klaften M et al (2009) Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in plasma enzyme activities as novel organ-specific disease models. Exp Physiol 94:412\u2013421","journal-title":"Exp Physiol"},{"key":"3_CR3","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1126\/science.1062960","volume":"294","author":"D Chabas","year":"2001","unstructured":"Chabas D, Baranzini SE, Mitchell D et al (2001) The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science 294:1731\u20131735","journal-title":"Science"},{"key":"3_CR4","doi-asserted-by":"publisher","first-page":"15884","DOI":"10.1073\/pnas.0806089105","volume":"105","author":"H Diao","year":"2008","unstructured":"Diao H, Iwabuchi K, Li L et al (2008) Osteopontin regulates development and function of invariant natural killer T cells. Proc Natl Acad Sci USA 105:15884\u201315889","journal-title":"Proc Natl Acad Sci USA"},{"key":"3_CR5","doi-asserted-by":"publisher","first-page":"2015","DOI":"10.1359\/jbmr.1999.14.12.2015","volume":"14","author":"KN Fedde","year":"1999","unstructured":"Fedde KN, Blair L, Silverstein J et al (1999) Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasia. J Bone Miner Res 14:2015\u20132026","journal-title":"J Bone Miner Res"},{"key":"3_CR6","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1002\/jbmr.1767","volume":"28","author":"BL Foster","year":"2013","unstructured":"Foster BL, Nagatomo KJ, Tso HW et al (2013) Tooth root dentin mineralization defects in a mouse model of hypophosphatasia. J Bone Miner Res 28:271\u2013282","journal-title":"J Bone Miner Res"},{"key":"3_CR7","doi-asserted-by":"publisher","first-page":"1199","DOI":"10.1016\/S0002-9440(10)63208-7","volume":"164","author":"D Harmey","year":"2004","unstructured":"Harmey D, Hessle L, Narisawa S et al (2004) Concerted regulation of inorganic pyrophosphate and osteopontin by Akp2, Enpp1, and Ank: an integrated model of the pathogenesis of mineralization disorders. Am J Pathol 164:1199\u20131209","journal-title":"Am J Pathol"},{"key":"3_CR8","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.1359\/jbmr.060619","volume":"21","author":"D Harmey","year":"2006","unstructured":"Harmey D, Johnson KA, Zelken J et al (2006) Elevated skeletal osteopontin levels contribute to the hypophosphatasia phenotype in Akp2\n                    \u2212\/\u2212\n                   mice. J Bone Miner Res 21:1377\u20131386","journal-title":"J Bone Miner Res"},{"key":"3_CR9","doi-asserted-by":"publisher","first-page":"9445","DOI":"10.1073\/pnas.142063399","volume":"99","author":"L Hessle","year":"2002","unstructured":"Hessle L, Johnson KA, Anderson HC et al (2002) Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization. Proc Natl Acad Sci USA 99:9445\u20139449","journal-title":"Proc Natl Acad Sci USA"},{"key":"3_CR10","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1126\/science.289.5477.265","volume":"289","author":"AM Ho","year":"2000","unstructured":"Ho AM, Johnson MD, Kingsley DM (2000) Role of the mouse ank gene in control of tissue calcification and arthritis. Science 289:265\u2013270","journal-title":"Science"},{"key":"3_CR11","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.1359\/jbmr.070515","volume":"22","author":"TA Hough","year":"2007","unstructured":"Hough TA, Polewski M, Johnson K et al (2007) Novel mouse model of autosomal semidominant adult hypophosphatasia has a splice site mutation in the tissue nonspecific alkaline phosphatase gene Akp2. J Bone Miner Res 22:1397\u20131407","journal-title":"J Bone Miner Res"},{"key":"3_CR12","doi-asserted-by":"publisher","first-page":"20197","DOI":"10.1074\/jbc.M909174199","volume":"275","author":"S Jono","year":"2000","unstructured":"Jono S, Peinado C, Giachelli CM (2000) Phosphorylation of osteopontin is required for inhibition of vascular smooth muscle cell calcification. J Biol Chem 275:20197\u201320203","journal-title":"J Biol Chem"},{"key":"3_CR13","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1016\/j.bone.2012.12.048","volume":"53","author":"CH Linder","year":"2013","unstructured":"Linder CH, Englund UH, Narisawa S et al (2013) Isozyme profile and tissue-origin of alkaline phosphatases in mouse serum. Bone 53:399\u2013408","journal-title":"Bone"},{"key":"3_CR14","doi-asserted-by":"crossref","unstructured":"Lobe CG, Koop KE, Kreppner W et al (1999) Z\/AP, a double reporter for cre-mediated recombination. Dev Biol 208:281\u2013292","DOI":"10.1006\/dbio.1999.9209"},{"key":"3_CR15","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1002\/(SICI)1526-968X(200002)26:2<116::AID-GENE4>3.0.CO;2-X","volume":"26","author":"H Lomeli","year":"2000","unstructured":"Lomeli H, Ramos-Mejia V, Gertsenstein M et al (2000) Targeted insertion of Cre recombinase into the TNAP gene: excision in primordial germ cells. Genesis 26:116\u2013117","journal-title":"Genesis"},{"key":"3_CR16","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1242\/dev.121.5.1487","volume":"121","author":"GR MacGregor","year":"1995","unstructured":"MacGregor GR, Zambrowicz BP, Soriano P (1995) Tissue non-specific alkaline phosphatase is expressed in both embryonic and extraembryonic lineages during mouse embryogenesis but is not required for migration of primordial germ cells. Development 121:1487\u20131496","journal-title":"Development"},{"key":"3_CR17","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1359\/jbmr.071213","volume":"23","author":"JL Millan","year":"2008","unstructured":"Millan JL, Narisawa S, Lemire I et al (2008) Enzyme replacement therapy for murine hypophosphatasia. J Bone Miner Res 23:777\u2013787","journal-title":"J Bone Miner Res"},{"key":"3_CR18","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1101\/gad.1276205","volume":"19","author":"M Murshed","year":"2005","unstructured":"Murshed M, Harmey D, Millan JL et al (2005) Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone. Genes Dev 19:1093\u20131104","journal-title":"Genes Dev"},{"key":"3_CR19","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1002\/(SICI)1097-0177(199703)208:3<432::AID-AJA13>3.0.CO;2-1","volume":"208","author":"S Narisawa","year":"1997","unstructured":"Narisawa S, Frohlander N, Millan JL (1997) Inactivation of two mouse alkaline phosphatase genes and establishment of a model of infantile hypophosphatasia. Dev Dyn 208:432\u2013446","journal-title":"Dev Dyn"},{"key":"3_CR20","doi-asserted-by":"publisher","first-page":"1700","DOI":"10.1359\/jbmr.070714","volume":"22","author":"S Narisawa","year":"2007","unstructured":"Narisawa S, Harmey D, Yadav MC et al (2007) Novel inhibitors of alkaline phosphatase suppress vascular smooth muscle cell calcification. J Bone Miner Res 22:1700\u20131710","journal-title":"J Bone Miner Res"},{"key":"3_CR21","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1002\/aja.1002010306","volume":"201","author":"S Narisawa","year":"1994","unstructured":"Narisawa S, Hasegawa H, Watanabe K et al (1994) Stage-specific expression of alkaline phosphatase during neural development in the mouse. Dev Dyn 201:227\u2013235","journal-title":"Dev Dyn"},{"key":"3_CR22","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1002\/1096-9896(2000)9999:9999<::AID-PATH722>3.0.CO;2-Y","volume":"193","author":"S Narisawa","year":"2001","unstructured":"Narisawa S, Wennberg C, Millan JL (2001) Abnormal vitamin B6 metabolism in alkaline phosphatase knock-out mice causes multiple abnormalities, but not the impaired bone mineralization. J Pathol 193:125\u2013133","journal-title":"J Pathol"},{"key":"3_CR23","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.1002\/jbmr.1901","volume":"28","author":"S Narisawa","year":"2013","unstructured":"Narisawa S, Yadav MC, Millan JL (2013) In vivo overexpression of tissue-nonspecific alkaline phosphatase increases skeletal mineralization and affects the phosphorylation status of osteopontin. J Bone Miner Res 28:1587\u20131598","journal-title":"J Bone Miner Res"},{"key":"3_CR24","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1359\/jbmr.1998.13.7.1101","volume":"13","author":"SR Rittling","year":"1998","unstructured":"Rittling SR, Matsumoto HN, McKee MD et al (1998) Mice lacking osteopontin show normal development and bone structure but display altered osteoclast formation in vitro. J Bone Miner Res 13:1101\u20131111","journal-title":"J Bone Miner Res"},{"key":"3_CR25","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1007\/s00335-012-9397-z","volume":"23","author":"S Sabrautzki","year":"2012","unstructured":"Sabrautzki S, Rubio-Aliaga I, Hans W et al (2012) New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis. Mamm Genome 23:416\u2013430","journal-title":"Mamm Genome"},{"key":"3_CR26","unstructured":"Sali A, Favaloro J, Terkeltaub R et al (1999) Germline deletion of the nucleoside triphosphate pyrophosphohydrolase (NTPPPH) plasma cell glycoprotein (PC-1) produces abnormal calcification of periarticular tissues. In: Vanduffel L, Lemmens R (eds) Ecto-ATPases and related ectonucleotidases: proceedings of the second international workshop on Ecto-ATPases and related ecotonucleotidases, 1st edn. Shaker Publishing B.V., Diepenbeek, pp 267\u2013282"},{"key":"3_CR27","first-page":"85","volume":"43","author":"MJ Skynner","year":"1999","unstructured":"Skynner MJ, Drage DJ, Dean WL et al (1999) Transgenic mice ubiquitously expressing human placental alkaline phosphatase (PLAP): an additional reporter gene for use in tandem with beta-galactosidase. Int J Dev Biol 43:85\u201390","journal-title":"Int J Dev Biol"},{"key":"3_CR28","doi-asserted-by":"crossref","unstructured":"Sheen CR, Kuss P, Narisawa S et al (2015) Pathophysiological role of vascular smooth muscle alkaline phosphatase in medial artery calcification. J Bone Miner Res 30:824\u2013836","DOI":"10.1002\/jbmr.2420"},{"key":"3_CR29","doi-asserted-by":"publisher","first-page":"E686","DOI":"10.1152\/ajpendo.00552.2003","volume":"286","author":"R Vattikuti","year":"2004","unstructured":"Vattikuti R, Towler DA (2004) Osteogenic regulation of vascular calcification: an early perspective. Am J Physiol Endocrinol Metab 286:E686\u2013E696","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"3_CR30","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1038\/ng0995-45","volume":"11","author":"KG Waymire","year":"1995","unstructured":"Waymire KG, Mahuren JD, Jaje JM et al (1995) Mice lacking tissue non-specific alkaline phosphatase die from seizures due to defective metabolism of vitamin B-6. Nat Genet 11:45\u201351","journal-title":"Nat Genet"},{"key":"3_CR31","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1056\/NEJMoa1106173","volume":"366","author":"MP Whyte","year":"2012","unstructured":"Whyte MP, Greenberg CR, Salman NJ et al (2012) Enzyme-replacement therapy in life-threatening hypophosphatasia. N Engl J Med 366:904\u2013913","journal-title":"N Engl J Med"},{"key":"3_CR32","doi-asserted-by":"publisher","first-page":"1722","DOI":"10.1002\/jbmr.1619","volume":"27","author":"MC Yadav","year":"2012","unstructured":"Yadav MC, de Oliveira RC, Foster BL et al (2012) Enzyme replacement prevents enamel defects in hypophosphatasia mice. J Bone Miner Res 27:1722\u20131734","journal-title":"J Bone Miner Res"},{"key":"3_CR33","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1002\/jbmr.195","volume":"26","author":"MC Yadav","year":"2011","unstructured":"Yadav MC, Simao AM, Narisawa S et al (2011) Loss of skeletal mineralization by the simultaneous ablation of PHOSPHO1 and alkaline phosphatase function: a unified model of the mechanisms of initiation of skeletal calcification. J Bone Miner Res 26:286\u2013297","journal-title":"J Bone Miner Res"},{"key":"3_CR34","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1002\/jbmr.201","volume":"26","author":"S Yamamoto","year":"2011","unstructured":"Yamamoto S, Orimo H, Matsumoto T et al (2011) Prolonged survival and phenotypic correction of Akp2\n                    \u2212\/\u2212\n                   hypophosphatasia mice by lentiviral gene therapy. J Bone Miner Res 26:135\u2013142","journal-title":"J Bone Miner Res"},{"key":"3_CR35","doi-asserted-by":"publisher","first-page":"8156","DOI":"10.1073\/pnas.96.14.8156","volume":"96","author":"H Yoshitake","year":"1999","unstructured":"Yoshitake H, Rittling SR, Denhardt DT et al (1999) Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption. Proc Natl Acad Sci USA 96:8156\u20138160","journal-title":"Proc Natl Acad Sci USA"}],"container-title":["Subcellular Biochemistry","Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/978-94-017-7197-9_3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T21:04:38Z","timestamp":1674248678000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/978-94-017-7197-9_3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"ISBN":["9789401771962","9789401771979"],"references-count":35,"URL":"https:\/\/doi.org\/10.1007\/978-94-017-7197-9_3","relation":{},"ISSN":["0306-0225"],"issn-type":[{"type":"print","value":"0306-0225"}],"subject":[],"published":{"date-parts":[[2015]]},"assertion":[{"value":"29 July 2015","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}